- Overview
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Dr. Deyell is a pediatric oncologist/hematologist and clinician investigator at BC Children’s Hospital and Research Institute. She is a co-leader of the BC Pediatric Precision OncoGenomics study (PedsPOG) and of the Clinical Node for the national PRecision Oncology For Young peopLE (PROFYLE) program. She leads the Developmental Therapeutics program in pediatric oncology/hematology in BC, and participates in the national C17 DVL network.
- Publications
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Whole Abdominal Radiotherapy Is Tolerable and Effective in Children and Young Adults With Intra-Abdominal Sarcoma: A Canadian Sarcoma Research and Clinical Collaboration (CanSaRCC) Study
Pediatric Blood & Cancer
Rebecca J. Deyell and Hagit Peretz Soroka and Delaney Sharp and Caroline Ruus and Jeffrey N. Bone and Mai-Kim Gervais and Audrey Roux and Xiaolan Feng and Natalie Logie and Nicolas Prudhomme and Caroline Holloway and Abha A. Gupta and Derek S. Tsang
DOI: 10.1002/pbc.31768
08/2025Osteosarcoma in an Adolescent With Germline DYNC1H1-Related Disorder: A Novel Association With Whole Genome and Transcriptome Tumour Analysis
Pediatric Blood & Cancer
Cameron J. Grisdale and Rachel V. Silverberg and Bilal M. Marwa and Trevor J. Loback and Alysa A. Poulin and Kaveer K. Chatoorgoon and Saima Alvi and Shahrad R. Rassekh and Rebecca J. Deyell and Paul R. D'Alessandro
DOI: 10.1002/pbc.31592
05/2025Data from Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez-Ramirez and Ayse B. Ercan and Lucie Stengs and Jiil Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.c.6678040.v3
09/2024Suppl Figure S1 from Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez-Ramirez and Ayse B. Ercan and Lucie Stengs and Jiil Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.27031396.v1
09/2024Trial protocol 1 from Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez-Ramirez and Ayse B. Ercan and Lucie Stengs and Jiil Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.27031387
09/2024Supplementary Table S1 from Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez-Ramirez and Ayse B. Ercan and Lucie Stengs and Jiil Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.27031390.v1
09/2024Suppl Table S2 from Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez-Ramirez and Ayse B. Ercan and Lucie Stengs and Jiil Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.27031393
09/2024Access to innovative therapies in pediatric oncology: Report of the nationwide experience in Canada
Cancer Medicine
Judd, S. and Revon-Riviere, G. and Grover, S.A. and Deyell, R.J. and Vanan, M.I. and Lewis, V.A. and Pecheux, L. and Zorzi, A.P. and Goudie, C. and Santiago, R. and Tran, T.H. and Abbott, L.S. and Brossard, J. and Moorehead, P. and Alvi, S. and Portwine, C. and Denburg, A. and Whitlock, J.A. and Cohen-Gogo, S. and Morgenstern, D.A.
DOI: 10.1002/cam4.7033
2024Whole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers
Nature Communications
Deyell, R.J. and Shen, Y. and Titmuss, E. and Dixon, K. and Williamson, L.M. and Pleasance, E. and Nelson, J.M.T. and Abbasi, S. and Krzywinski, M. and Armstrong, L. and Bonakdar, M. and Ch?ng, C. and Chuah, E. and Dunham, C. and Fok, A. and Jones, M. and Lee, A.F. and Ma, Y. and Moore, R.A. and Mungall, A.J. and Mungall, K.L. and Rogers, P.C. and Schrader, K.A. and Virani, A. and Wee, K. and Young, S.S. and Zhao, Y. and Jones, S.J.M. and Laskin, J. and Marra, M.A. and Rassekh, S.R.
DOI: 10.1038/s41467-024-48363-5
2024Proteomics and personalized patient-derived xenograft models identify treatment opportunities for a progressive malignancy within a clinically actionable timeframe and change care
medRxiv
Barnabas, G.D. and Bhat, T.A. and Goebeler, V. and Leclair, P. and Azzam, N. and Melong, N. and Anderson, C. and Gom, A. and An, S. and Ergin, E.K. and Shen, Y. and Mungall, A.J. and Mungall, K.L. and Maxwell, C.A. and Reid, G.S.D. and Hirst, M. and Jones, S. and Chan, J.A. and Senger, D.L. and Berman, J.N. and Parker, S.J. and Bush, J.W. and Strahlendorf, C. and Deyell, R.J. and Lim, C.J. and Lange, P.F.
DOI: 10.1101/2024.07.04.24309923
2024Effect of distance to tertiary centre on enrolment of paediatric patients with relapsed or refractory cancer on early phase clinical trials in British Columbia
Paediatrics and Child Health (Canada)
D'Alessandro, P.R. and Bone, J.N. and Davis, J.F. and Potts, J.E. and Deyell, R.J.
DOI: 10.1093/pch/pxad044
2024Data from Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez Ramirez and Ayse B. Ercan and Lucie Stengs and Jill Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.c.6678040.v2
12/2023Suppl Figure S1 from Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez Ramirez and Ayse B. Ercan and Lucie Stengs and Jill Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.23284771.v1
06/2023Trial protocol 1 from Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez Ramirez and Ayse B. Ercan and Lucie Stengs and Jill Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.23284759
06/2023Supplementary Table S1 from Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez Ramirez and Ayse B. Ercan and Lucie Stengs and Jill Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.23284762.v1
06/2023Suppl Table S2 from Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency
Anirban Das and Uri Tabori and Lauren C. Sambira Nahum and Natalie B. Collins and Rebecca Deyell and Rina Dvir and Cecile Faure-Conter and Timothy E. Hassall and Jane E. Minturn and Melissa Edwards and Elissa Brookes and Vanessa Bianchi and Adrian Levine and Simone C. Stone and Sumedha Sudhaman and Santiago Sanchez Ramirez and Ayse B. Ercan and Lucie Stengs and Jill Chung and Logine Negm and Gad Getz and Yosef E. Maruvka and Birgit Ertl-Wagner and Pamela S. Ohashi and Trevor Pugh and Cynthia Hawkins and Eric Bouffet and Daniel A. Morgenstern
DOI: 10.1158/1078-0432.23284768.v1
06/2023Immunohistochemical Study of Histone Protein 3 Modification in Pediatric Osteosarcoma Identifies Reduced H3K27me3 as a Marker of Poor Treatment Response
medRxiv
Kondratowski, S. and Cohen, D. and Deyell, R.J. and Sandhu, A. and Bush, J.W.
DOI: 10.1101/2023.09.13.23295510
2023Prediction of whole body composition utilizing cross-sectional abdominal imaging in pediatrics
European Journal of Clinical Nutrition
Deyell, R.J. and Desai, S. and Gallivan, A. and Lim, A. and Sawyer, M.B. and Heymsfield, S.B. and Shen, W. and Baracos, V.E.
DOI: 10.1038/s41430-023-01272-0
2023Human ASXL1 Deficiency Causes Epigenetic Dysfunction, Combined Immunodeficiency and EBV–Associated Hodgkin Lymphoma
medRxiv
Fu, M.P. and Sharma, M. and Merrill, S.M. and Yousefi, P. and Tan, R. and Modi, B.P. and Bel, K.D. and Deyell, R.J. and Rozmus, J. and Rehmus, W. and Hildebrand, K.J. and James, E. and Blanchard-Rohner, G. and Lin, S. and Shopsowitz, K.E. and Setiadi, A. and Terry, J. and Lee, A.F. and Drögemöller, B.I. and Matthews, A. and Tarailo-Graovac, M. and Sauvé, L. and Mitchell, H. and Prendiville, J.S. and MacIsaac, J.L. and Dever, K. and Lin, D.T.S. and Meijer, M. and Ross, C.J.D. and Dobson, S.R.M. and Vercauteren, S.M. and Wasserman, W.W. and van Karnebeek, C.D.M. and McKinnon, M.L. and Kobor, M.S. and Turvey, S.E. and Biggs, C.M.
DOI: 10.1101/2023.12.20.23300096
2023Ensuring access to innovative therapies for children, adolescents, and young adults across Canada: The single patient study experience
Paediatrics and Child Health (Canada)
Revon-Riviere, G. and Young, L.C. and Stephenson, E.A. and Brodeur-Robb, K. and Cohen-Gogo, S. and Deyell, R. and Lacaze-Masmonteil, T. and Palmer, A. and Parekh, R.S. and Whitlock, J.A. and Morgenstern, D.A.
DOI: 10.1093/pch/pxac122
2023Brentuximab vedotin after autologous transplantation in pediatric patients with relapsed/refractory Hodgkin lymphoma
Blood Advances
Forlenza, C.J. and Rosenzweig, J. and Mauguen, A. and Buhtoiarov, I. and Cuglievan, B. and Dave, H. and Deyell, R.J. and Flerlage, J.E. and Franklin, A.K. and Krajewski, J. and Leger, K.J. and Marks, L.J. and Norris, R.E. and Pacheco, M. and Willen, F. and Yan, A.P. and Harker-Murray, P.D. and Giulino-Roth, L.
DOI: 10.1182/bloodadvances.2022009323
2023Performance of the eHealth decision support tool, MIPOGG, for recognising children with Li-Fraumeni, DICER1, Constitutional mismatch repair deficiency and Gorlin syndromes
Journal of Medical Genetics
Hebert, R. and Cullinan, N. and Armstrong, L. and Blood, K.A. and Brossard, J. and Brunga, L. and Cacciotti, C. and Caswell, K. and Cellot, S. and Coltin, H. and Deyell, R.J. and Felton, K. and Fernandez, C.V. and Fleming, A.J. and Gibson, P. and Hammad, R. and Jabado, N. and Johnston, D.L. and Lafay-Cousin, L. and Larouche, V. and Leblanc-Desrochers, C. and Michaeli, O. and Perrier, R. and Pike, M. and Say, J. and Schiller, I. and Toupin, A.-K. and Vairy, S. and Van Engelen, K. and Waespe, N. and Villani, A. and Foulkes, W.D. and Malkin, D. and Reichman, L. and Goudie, C.
DOI: 10.1136/jmg-2023-109376
2023Whole genome transcriptome analysis in a case of a neonatal soft tissue sarcoma with YWHAE:NUTM2B fusion
Pediatric Blood and Cancer
Locke, A. and Terry, J. and Shen, Y. and Courtemanche, D. and Rosenbaum, D.G. and Rassekh, S.R. and Deyell, R.J. and Cheng, S.
DOI: 10.1002/pbc.30310
2023Parents’ expectations, preferences, and recall of germline findings in a childhood cancer precision medicine trial
Cancer
McGill, B.C. and Wakefield, C.E. and Tucker, K.M. and Daly, R.A. and Donoghoe, M.W. and Vetsch, J. and Warby, M. and Fuentes-Bolanos, N.A. and Barlow-Stewart, K. and Kirk, J. and Courtney, E. and O?Brien, T.A. and Marshall, G.M. and Pinese, M. and Cowley, M.J. and Tyrrell, V. and Deyell, R.J. and Ziegler, D.S. and Hetherington, K.
DOI: 10.1002/cncr.34917
2023Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency
Clinical cancer research : an official journal of the American Association for Cancer Research
Das, A. and Tabori, U. and Sambira Nahum, L.C. and Collins, N.B. and Deyell, R. and Dvir, R. and Faure-Conter, C. and Hassall, T.E. and Minturn, J.E. and Edwards, M. and Brookes, E. and Bianchi, V. and Levine, A. and Stone, S.C. and Sudhaman, S. and Sanchez Ramirez, S. and Ercan, A.B. and Stengs, L. and Chung, J. and Negm, L. and Getz, G. and Maruvka, Y.E. and Ertl-Wagner, B. and Ohashi, P.S. and Pugh, T. and Hawkins, C. and Bouffet, E. and Morgenstern, D.A.
DOI: 10.1158/1078-0432.CCR-23-0411
2023Diagnostic and treatment intervals are not associated with survival in rhabdomyosarcoma: A Cancer in Young People in Canada study
Pediatric Blood & Cancer
Sapna Oberoi and Pascal Lambert and Abha A. Gupta and Rebecca J. Deyell and Lillian Sung and Geoffrey D. E. Cuvelier
DOI: 10.1002/pbc.29306
01/2022Catecholamines in neuroblastoma: Driver of hypertension, or solely a marker of disease?
Cancer Reports
Harding, M. and Deyell, R.J. and Blydt-Hansen, T.
DOI: 10.1002/cnr2.1569
2022Quality of Life (QoL) of Children and Adolescents Participating in a Precision Medicine Trial for High-Risk Childhood Cancer
Cancers
Hetherington, K. and Wakefield, C.E. and Kunalan, K.P.K. and Donoghoe, M.W. and McGill, B.C. and Fardell, J.E. and Daly, R. and Deyell, R.J. and Ziegler, D.S.
DOI: 10.3390/cancers14215310
2022Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors: A C17 Canadian Phase I Clinical Trial
Cancers
Manji, A. and Samson, Y. and Deyell, R.J. and Johnston, D.L. and Lewis, V.A. and Zorzi, A.P. and Berman, J.N. and Brodeur-Robb, K. and Morrison, E. and Kee, L. and Kumar, S. and Baruchel, S. and Whitlock, J.A. and Morgenstern, D.A.
DOI: 10.3390/cancers14122985
2022Residual meta-iodobenzyl guanidine (MIBG) positivity following therapy for metastatic neuroblastoma: Patient characteristics, imaging, and outcome
Pediatric Blood & Cancer
Nida Usmani and Rebecca J. Deyell and Carol Portwine and Margarida Simao Rafael and Paul C. Moorehead and Amer Shammas and Reza Vali and Mateo Farfan and Thuvaraha Vanniyasingam and Daniel A. Morgenstern and Meredith S. Irwin
DOI: 10.1002/pbc.29289
12/2021Crizotinib response in a neuroblastoma patient with a constitutional mosaic anaplastic lymphoma kinase I1170N-activating mutation
Pediatric Blood & Cancer
Melissa Harvey and Meredith S. Irwin and Linlea Armstrong and Kim Seath and Sean Young and Sharon Gershony and Rebecca J. Deyell
DOI: 10.1002/pbc.28916
06/2021Canadian consensus on TRK-inhibitor therapy for NTRK fusion-positive sarcoma
International Journal of Cancer
Simmons, C. and Deyell, R.J. and MacNeill, A.J. and Vera-Badillo, F.E. and Smrke, A. and Abdul Razak, A.R. and Banerji, S. and McLeod, D. and Noujaim, J.
DOI: 10.1002/ijc.33723
2021Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury
npj Precision Oncology
Williamson, L.M. and Rive, C.M. and Di Francesco, D. and Titmuss, E. and Chun, H.-J.E. and Brown, S.D. and Milne, K. and Pleasance, E. and Lee, A.F. and Yip, S. and Rosenbaum, D.G. and Hasselblatt, M. and Johann, P.D. and Kool, M. and Harvey, M. and Dix, D. and Renouf, D.J. and Holt, R.A. and Nelson, B.H. and Hirst, M. and Jones, S.J.M. and Laskin, J. and Rassekh, S.R. and Deyell, R.J. and Marra, M.A.
DOI: 10.1038/s41698-021-00238-4
2021Life-Threatening Intratumoral Hemorrhage in an Infant with Hepatoblastoma Successfully Treated with Hepatic Arterial Embolization
Journal of Vascular and Interventional Radiology
Ronsley, R. and Cardarelli-Leite, L. and Burrill, J. and Deyell, R.J. and Heran, M.K.S.
DOI: 10.1016/j.jvir.2021.04.007
2021Precocious puberty: A red flag for malignancy in childhood
British Columbia Medical Journal
D?alessandro, P.R. and Hamilton, J. and Khatchadourian, K. and Lunaczek-Motyka, E. and Schultz, K.R. and Metzger, D. and Deyell, R.J.
2021Canadian consensus for biomarker testing and treatment of TRK fusion cancer in pediatric patients
Current Oncology
Perreault, S. and Chami, R. and Deyell, R.J. and Demellawy, D.E. and Ellezam, B. and Jabado, N. and Morgenstern, D.A. and Narendran, A. and Sorensen, P.H.B. and Wasserman, J.D. and Yip, S.
DOI: 10.3390/curroncol28010038
2021Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes
JAMA Oncology
Goudie, C. and Witkowski, L. and Cullinan, N. and Reichman, L. and Schiller, I. and Tachdjian, M. and Armstrong, L. and Blood, K.A. and Brossard, J. and Brunga, L. and Cacciotti, C. and Caswell, K. and Cellot, S. and Clark, M.E. and Clinton, C. and Coltin, H. and Felton, K. and Fernandez, C.V. and Fleming, A.J. and Fuentes-Bolanos, N. and Gibson, P. and Grant, R. and Hammad, R. and Harrison, L.W. and Irwin, M.S. and Johnston, D.L. and Kane, S. and Lafay-Cousin, L. and Lara-Corrales, I. and Larouche, V. and Mathews, N. and Meyn, M.S. and Michaeli, O. and Perrier, R. and Pike, M. and Punnett, A. and Ramaswamy, V. and Say, J. and Somers, G. and Tabori, U. and Thibodeau, M.L. and Toupin, A.-K. and Tucker, K.M. and Van Engelen, K. and Vairy, S. and Waespe, N. and Warby, M. and Wasserman, J.D. and Whitlock, J.A. and Sinnett, D. and Jabado, N. and Nathan, P.C. and Shlien, A. and Kamihara, J. and Deyell, R.J. and Ziegler, D.S. and Nichols, K.E. and Dendukuri, N. and Malkin, D. and Villani, A. and Foulkes, W.D.
DOI: 10.1001/jamaoncol.2021.4536
2021NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling
Clinical Case Reports
Britton, H.M. and Levine, A.B. and Shen, Y. and Mungall, K. and Serrano, J. and Snuderl, M. and Pleasance, E. and Jones, S.J.M. and Laskin, J. and Marra, M.A. and Rassekh, S.R. and Deyell, R. and Yip, S. and Cheng, S. and Dunham, C.
DOI: 10.1002/ccr3.3804
2021Parent Perspectives on Information-seeking, Trustworthiness, and Decision-making in High-risk Neuroblastoma.
Journal of pediatric hematology/oncology
Brown K and Benjaminy S and Illes J and Deyell RJ
DOI: 10.1097/mph.0000000000002022
PubMed: 33273412
12/2020Evaluating the quantity, quality and size distribution of cell-free DNA by multiplex droplet digital PCR.
Scientific reports
Alcaide M and Cheung M and Hillman J and Rassekh SR and Deyell RJ and Batist G and Karsan A and Wyatt AW and Johnson N and Scott DW and Morin RD
DOI: 10.1038/s41598-020-69432-x
PubMed: 32724107
07/2020Establishing a Framework for the Clinical Translation of Germline Findings in Precision Oncology.
JNCI cancer spectrum
Dixon K and Young S and Shen Y and Thibodeau ML and Fok A and Pleasance E and Zhao E and Jones M and Aubert G and Armstrong L and Virani A and Regier D and Gelmon K and Renouf D and Chia S and Schrader KA
DOI: 10.1093/jncics/pkaa045
PubMed: 33134827
05/2020Ifosfamide, gemcitabine, and vinorelbine is an effective salvage regimen with excellent stem cell mobilization in relapsed or refractory pediatric Hodgkin lymphoma
Pediatric Blood and Cancer
Marr, K. and Ronsley, R. and Nadel, H. and Douglas, K. and Gershony, S. and Strahlendorf, C. and Davis, J.H. and Deyell, R.J.
DOI: 10.1002/pbc.28167
2020The Utility of PET/CT in Guiding Radiotherapy Reduction for Children with Hodgkin Lymphoma Treated with ABVD
Journal of Pediatric Hematology/Oncology
Ingley, K.M. and Nadel, H.R. and Potts, J.E. and Wilson, D.C. and Eftekhari, A. and Deyell, R.J.
DOI: 10.1097/MPH.0000000000001534
2020ALK-Positive Lung Adenocarcinoma Arising in an Adolescent Treated for Relapsed Neuroblastoma
Journal of Thoracic Oncology
Alwelaie, Y. and Deyell, R.J. and Nadel, H.R. and Tucker, T. and Laskin, J. and Rassekh, S.R. and Zhou, C. and English, J.C. and Lee, A.F.
DOI: 10.1016/j.jtho.2019.02.010
2019Therapeutic implication of genomic landscape of adult metastatic sarcoma
JCO Precision Oncology
Feng, X. and Pleasance, E. and Zhao, E.Y. and Ng, T. and Grewal, J.K. and Mohammad, N. and Taylor, S.K. and Simmons, C. and Srikanthan, A. and Rod Rassekh, S. and Deyell, R. and Rauw, J. and Knowling, M. and Khoo, K. and Lee, U. and Noonan, K. and Hart, J. and Petter Tonseth, R. and Shen, Y. and Titmuss, E. and Jones, M. and Bonakdar, M. and Reisle, C. and Taylor, G.A. and Chan, S. and Mungall, K. and Chuah, E. and Zhao, Y. and Mungall, A. and Moore, R. and Lim, H. and Renouf, D.J. and Gelmon, K. and Yip, S. and Jones, S.J.M. and Marra, M. and Laskin, J.
DOI: 10.1200/PO.18.00325
2019Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer
JAMA network open
Vaske, O.M. and Bjork, I. and Salama, S.R. and Beale, H. and Tayi Shah, A. and Sanders, L. and Pfeil, J. and Lam, D.L. and Learned, K. and Durbin, A. and Kephart, E.T. and Currie, R. and Newton, Y. and Swatloski, T. and McColl, D. and Vivian, J. and Zhu, J. and Lee, A.G. and Leung, S.G. and Spillinger, A. and Liu, H.-Y. and Liang, W.S. and Byron, S.A. and Berens, M.E. and Resnick, A.C. and Lacayo, N. and Spunt, S.L. and Rangaswami, A. and Huynh, V. and Torno, L. and Plant, A. and Kirov, I. and Zabokrtsky, K.B. and Rassekh, S.R. and Deyell, R.J. and Laskin, J. and Marra, M.A. and Sender, L.S. and Mueller, S. and Sweet-Cordero, E.A. and Goldstein, T.C. and Haussler, D.
DOI: 10.1001/jamanetworkopen.2019.13968
2019Phase I dose-finding study for melatonin in pediatric oncology patients with relapsed solid tumors
Pediatric Blood and Cancer
Johnston, D.L. and Zupanec, S. and Nicksy, D. and Morgenstern, D. and Narendran, A. and Deyell, R.J. and Samson, Y. and Wu, B. and Baruchel, S.
DOI: 10.1002/pbc.27676
2019Phase I study of vinblastine and temsirolimus in pediatric patients with recurrent or refractory solid tumors: Canadian Cancer Trials Group Study IND.218
Pediatric Blood and Cancer
Deyell, R.J. and Wu, B. and Rassekh, S.R. and Tu, D. and Samson, Y. and Fleming, A. and Bouffet, E. and Sun, X. and Powers, J. and Seymour, L. and Baruchel, S. and Morgenstern, D.A.
DOI: 10.1002/pbc.27540
2019Pediatric oncology and stem cell transplant patients with healthcare-associated Clostridium difficile infection were already colonized on admission
Pediatric Blood and Cancer
Al-Rawahi, G.N. and Al-Najjar, A. and McDonald, R. and Deyell, R.J. and Golding, G.R. and Brant, R. and Tilley, P. and Thomas, E. and Rassekh, S.R. and O'Gorman, A. and Wong, P. and Turnham, L. and Dobson, S.
DOI: 10.1002/pbc.27604
2019Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies.
JNCI cancer spectrum
Lorentzian A and Biegel JA and Ostrow DG and Rolf N and Liu CC and Rassekh SR and Deyell RJ and Triche T and Schultz KR and Rozmus J and Reid GSD and Lim CJ and Lange PF and Maxwell CA
DOI: 10.1093/jncics/pky079
PubMed: 30976750
10/2018Comparative RNA-Sequencing Analysis Benefits a Pediatric Patient With Relapsed Cancer.
JCO precision oncology
Newton Y and Rassekh SR and Deyell RJ and Shen Y and Jones MR and Dunham C and Yip S and Leelakumari S and Zhu J and McColl D and Swatloski T and Salama SR and Ng T and Hendson G and Lee AF and Morozova O
04/2018Comparative RNA-sequencing analysis benefits a pediatric patient with relapsed cancer
JCO Precision Oncology
Newton, Y. and Rassekh, S.R. and Deyell, R.J. and Shen, Y. and Jones, M.R. and Dunham, C. and Yip, S. and Leelakumari, S. and Zhu, J. and McColl, D. and Swatloski, T. and Salama, S.R. and Ng, T. and Hendson, G. and Lee, A.F. and Ma, Y. and Moore, R. and Mungall, A.J. and Haussler, D. and Stuart, J.M. and Jantzen, C. and Laskin, J. and Jones, S.J.M. and Marra, M.A. and Morozova, O.
DOI: 10.1200/PO.17.00198
2018Developing liposomal nanomedicines for treatment of patients with neuroblastoma
Lipid Nanocarriers for Drug Targeting
Gilabert-Oriol, R. and Chernov, L. and Deyell, R.J. and Bally, M.B.
DOI: 10.1016/B978-0-12-813687-4.00009-8
2018Application of genomics to identify therapeutic targets in recurrent pediatric papillary thyroid carcinoma
Cold Spring Harbor Molecular Case Studies
Ronsley, R. and Rod Rassekh, S. and Shen, Y. and Lee, A.F. and Jantzen, C. and Halparin, J. and Albert, C. and Hawkins, D.S. and Amed, S. and Rothstein, R. and Mungall, A.J. and Dix, D. and Blair, G. and Nadel, H. and Jones, S.J.M. and Laskin, J. and Marra, M.A. and Deyell, R.J.
DOI: 10.1101/mcs.a002568
2018ABVD chemotherapy with reduced radiation therapy rates in children, adolescents and young adults with all stages of Hodgkin lymphoma.
Annals of Oncology
DOI: 10.1093/annonc/mdx005
PubMed: 28327925
04/2017Nivolumab in the Treatment of Refractory Pediatric Hodgkin Lymphoma
Journal of Pediatric Hematology/Oncology
Foran, A.E. and Nadel, H.R. and Lee, A.F. and Savage, K.J. and Deyell, R.J.
DOI: 10.1097/MPH.0000000000000703
2017Optimization of liposomal topotecan for use in treating neuroblastoma
Cancer Medicine
Chernov, L. and Deyell, R.J. and Anantha, M. and Dos Santos, N. and Gilabert-Oriol, R. and Bally, M.B.
DOI: 10.1002/cam4.1083
2017Targeted error-suppressed quantification of circulating tumor DNA using semi-degenerate barcoded adapters and biotinylated baits
Scientific Reports
Alcaide, M. and Yu, S. and Davidson, J. and Albuquerque, M. and Bushell, K. and Fornika, D. and Arthur, S. and Grande, B.M. and McNamara, S. and Tertre, M.C.D. and Batist, G. and Huntsman, D.G. and Cavallone, L. and Aguilar, A. and Basik, M. and Johnson, N.A. and Deyell, R.J. and Rassekh, S.R. and Morin, R.D.
DOI: 10.1038/s41598-017-10269-2
2017ETV6-NTRK3 is Expressed in a Subset of ALK-Negative Inflammatory Myofibroblastic Tumors
American Journal of Surgical Pathology
Alassiri, A.H. and Ali, R.H. and Shen, Y. and Lum, A. and Strahlendorf, C. and Deyell, R. and Rassekh, R. and Sorensen, P.H. and Laskin, J. and Marra, M. and Yip, S. and Lee, C.-H. and Ng, T.L.
DOI: 10.1097/PAS.0000000000000677
2016Lessons learned from the application of whole-genome analysis to the treatment of patients with advanced cancers.
Cold Spring Harbor Molecular Case Studies
DOI: 10.1101/mcs.a000570
PubMed: 27148575
10/2015Molecular oncology of neuroblastoma
Molecular Oncology: Causes of Cancer and Targets for Treatment
Batra, V. and Deyell, R.J. and Maris, J.M.
DOI: 10.1017/CBO9781139046947.060
2015Dexmedetomidine and hydromorphone: A novel pain management strategy for the oncology ward setting during anti-GD2 immunotherapy for high-risk neuroblastoma in children
Pediatric Blood and Cancer
Görges, M. and West, N. and Deyell, R. and Winton, P. and Cheung, W. and Lauder, G.
DOI: 10.1002/pbc.25197
2015Antidepressant use among survivors of childhood, adolescent, and young adult cancer: Letter to the editor response
Pediatric Blood and Cancer
Deyell, R.J. and Lorenzi, M. and Spinelli, J.J. and Mcbride, M.L.
DOI: 10.1002/pbc.24885
2014Neuroblastoma in older children, adolescents and young adults: A report from the International Neuroblastoma Risk Group project
Pediatric Blood and Cancer
Mossé, Y.P. and Deyell, R.J. and Berthold, F. and Nagakawara, A. and Ambros, P.F. and Monclair, T. and Cohn, S.L. and Pearson, A.D. and London, W.B. and Matthay, K.K.
DOI: 10.1002/pbc.24777
2014Paroxysmal nocturnal haemoglobinuria phenotype cells and leucocyte subset telomere length in childhood acquired aplastic anaemia
British Journal of Haematology
Tutelman, P.R. and Aubert, G. and Milner, R.A. and Dalal, B.I. and Schultz, K.R. and Deyell, R.J.
DOI: 10.1111/bjh.12656
2014Antidepressant use among survivors of childhood, adolescent and young adult cancer: A report of the childhood, adolescent and young adult cancer survivor (CAYACS) research program
Pediatric Blood and Cancer
Deyell, R.J. and Lorenzi, M. and Ma, S. and Rassekh, S.R. and Collet, J.-P. and Spinelli, J.J. and Mcbride, M.L.
DOI: 10.1002/pbc.24446
2013Immunosuppressive therapy without hematopoietic growth factor exposure in pediatric acquired aplastic anemia
Pediatric Hematology and Oncology
Deyell, R.J. and Shereck, E.B. and Milner, R.A. and Schultz, K.R.
DOI: 10.3109/08880018.2011.568043
2011Advances in the understanding of constitutional and somatic genomic alterations in neuroblastoma
Cancer Genetics
Deyell, R.J. and Attiyeh, E.F.
DOI: 10.1016/j.cancergen.2011.03.001
2011Costs and consequences of immunosuppressive therapy in children with aplastic anemia
Haematologica
Shereck, E.B. and Deyell, R.J. and Kurre, P.
DOI: 10.3324/haematol.2011.044917
2011Low oxygen saturation by pulse oximetry may be associated with a low oxygen affinity hemoglobin variant, hemoglobin Titusville
Journal of Pediatric Hematology/Oncology
Deyell, R. and Jackson, S. and Spier, S. and Le, D. and Poon, M.-C.
DOI: 10.1097/01.mph.0000200685.33291.0a
2006 - Research
-
Grants
Clinician Investigator Program, University of British Columbia, 2009-2011
Honours & AwardsJohn Snow Prize, Epidemiologic methods, University of British Columbia, November 2010
Laura MacRae Subspecialty Resident Award, BC Children’s Hospital, 2010
Research Group MembersChandan Harikrishna, Clinical Research Associate
Hina Johnstone, Research and Facilitation, Research and Facilitation, Clinical Research Coordinator
Saatvik Kurup, INSPIRE PROGRAM TRAINEE
Caitlin Mungall, Staff Member
Caroline Ruus, CRA
Lauren Ung, Student
OPTIMISE trial seeks to personalize cancer treatment for children with high-risk tumours
Dr. Rebecca Deyell will be leading the OPTIMISE trial — short for Optimal Precision Therapies to CustoMISE Care in Childhood and Adolescent Cancer — at BC Children's Hospital. The trial is designed to match children, adolescents and young adults with high-risk cancers to targeted therapies based on the genetic makeup of their tumours.
