Overview

My research interests range from studies involving paediatric hip, lower limbs, feet, trauma and bone tumours. I am specifically interested in advancing research around paediatric bone health and mobility. In addition to looking at the clinical outcomes, I am also interested in looking at the outcomes reported directly by the patients or caregivers of patients, specifically their quality of life. By studying these outcomes, I am aiming to look at the effectiveness of treatments I use in clinic and to explore ways to improve the quality of life of my patients. I also collaborate with biomechanical engineers to generate computerised models of the hip in order to imitate different deformities around the hip joint.

Publications

Danish Linguistic Validation and Cultural Adaptation of the LIMB-Q Kids
Children
Christopher Emil Jønsson and Lotte Poulsen and Jan Duedal Rölfing and Harpreet Chhina and Anthony Cooper and Jens Ahm Sørensen
DOI: 10.3390/children10071107
06/2023

Early Investigation and Bracing in DDH Impacts Maternal Wellbeing and Breastfeeding
Journal of Pediatric Orthopaedics
Hoffer, A. and Chhina, H. and Mulpuri, K. and Cooper, A.P.
DOI: 10.1097/BPO.0000000000002274
2023

LIMB-Q Kids—German Translation and Cultural Adaptation
Children
Bjoern Vogt and Jana Fresen and Georg Gosheger and Harpreet Chhina and Carolin Sophie Brune and Gregor Toporowski and Adrien Frommer and Andrea Laufer and Anthony Cooper and Robert Rödl and Jan Duedal Rölfing
DOI: 10.3390/children9091405
09/2022

Establishing content validity of LIMB-Q Kids: a new patient-reported outcome measure for lower limb deformities
Quality of Life Research
Harpreet Chhina and Anne Klassen and David Bade and Jacek Kopec and Anthony Cooper
DOI: 10.1007/s11136-022-03140-z
09/2022

Efficacy and Safety of "sleeper Plate" in Temporary Hemiepiphysiodesis and the Observation of "tethering"
Journal of Pediatric Orthopaedics
Gerges, M. and Messner, J. and Lim, B. and Chhina, H. and Cooper, A.
DOI: 10.1097/BPO.0000000000002184
2022

Late Ankle Reconstruction in a Child with Remote Traumatic Medial Malleolus Loss: Clinical and Radiographic Outcomes
Strategies in Trauma and Limb Reconstruction
Ponton, E. and Bakkai, A. and Courtemanche, D.J. and Cooper, A.P.
DOI: 10.5005/jp-journals-10080-1552
2022

Efficacy and Safety of "Sleeper Plate" in Temporary Hemiepiphysiodesis and the Observation of "Tethering"
Journal of Pediatric Orthopaedics
Messner, J. and Cooper, A.
DOI: 10.1097/BPO.0000000000002257
2022

Human complete NFAT1 deficiency causes a triad of joint contractures, osteochondromas, and B-cell malignancy
Blood
Sharma, M. and Fu, M.P. and Lu, H.Y. and Sharma, A.A. and Modi, B.P. and Michalski, C. and Lin, S. and Dalmann, J. and Salman, A. and Del Bel, K.L. and Waqas, M. and Terry, J. and Setiadi, A. and Lavoie, P.M. and Wasserman, W.W. and Mwenifumbo, J. and Kobor, M.S. and Lee, A.F. and Kuchenbauer, F. and Lehman, A. and Cheng, S. and Cooper, A. and Patel, M.S. and Turvey, S.E.
DOI: 10.1182/blood.2022015674
2022

Human germline biallelic complete NFAT1 deficiency causes the triad of progressive joint contractures, osteochondromas, and susceptibility to B cell malignancy
medRxiv
Sharma, M. and Fu, M.P. and Lu, H.Y. and Sharma, A.A. and Modi, B.P. and Michalski, C. and Lin, S. and Dalmann, J. and Salman, A. and Del Bel, K.L. and Waqas, M. and Terry, J. and Setiadi, A. and Lavoie, P.M. and Wasserman, W.W. and Mwenifumbo, J. and Kobor, M.S. and Lee, A.F. and Lehman, A. and Cheng, S. and Cooper, A. and Patel, M.S. and Turvey, S.E.
DOI: 10.1101/2022.01.30.22269378
2022

Paediatric elbow fractures and public play spaces: adherence to standards for children’s playground equipment and surfacing
BMJ Paediatrics Open
Jennifer Smith and Harpreet Chhina and Pardeep Sidhu and Mariana Brussoni and Ian Pike and Anthony Cooper
DOI: 10.1136/bmjpo-2021-001125
11/2021

What matters to children with lower limb deformities: an international qualitative study guiding the development of a new patient-reported outcome measure.
Journal of patient-reported outcomes
DOI: 10.1186/s41687-021-00299-w
PubMed: 33792793
04/2021

Clinical outcomes in pediatric tibial lengthening and deformity correction: a comparison of the Taylor Spatial Frame with the Orthex Hexapod System.
Journal of children's orthopaedics
DOI: 10.1302/1863-2548.15.200165
PubMed: 34040657
04/2021

Inter-rater and Intra-rater Reliability in the Radiographic Diagnosis of Growth Arrest in Paediatric Physeal Fractures
Indian Journal of Orthopaedics
Banting, N. and Schaeffer, E.K. and Bone, J. and Habib, E. and Hooper, N. and Reilly, C.W. and Cooper, A. and Mulpuri, K.
DOI: 10.1007/s43465-020-00327-9
2021

Correction of genu recurvatum deformity using a hexapod frame: A case series and review of the literature
Strategies in Trauma and Limb Reconstruction
Johnson, L. and McCammon, J. and Cooper, A.
DOI: 10.5005/JP-JOURNALS-10080-1528
2021

Survey of the impact of COVID-19 on pediatric orthopaedic surgeons globally
Journal of Pediatric Orthopaedics
Gibbard, M. and Ponton, E. and Sidhu, B.V. and Farrell, S. and Bone, J.N. and Wu, L.A. and Schaeffer, E. and Cooper, A. and Aroojis, A. and Mulpuri, K.
DOI: 10.1097/BPO.0000000000001887
2021

3-D Ultrasound Imaging Reliability of Measuring Dysplasia Metrics in Infants
Ultrasound in Medicine and Biology
Quader, N. and Hodgson, A.J. and Mulpuri, K. and Cooper, A. and Garbi, R.
DOI: 10.1016/j.ultrasmedbio.2020.08.008
2021

Is the modified Gartland classification system important in deciding the need for operative management of supracondylar humerus fractures?
Journal of children's orthopaedics
Teo TL and Schaeffer EK and Habib E and El-Hawary R and Larouche P and Shore B and Aarvold A and Carsen S and Reilly C and Mulpuri K
DOI: 10.1302/1863-2548.14.200093
PubMed: 33343744
12/2020

Methodological Challenges in Investigating Supracondylar Fractures of the Humerus From a Child’s Viewpoint: Evolution of Study Protocol
JMIR Research Protocols
Brittany Tara Lim and Harpreet Chhina and Ian Pike and Mariana Brussoni and Anthony Cooper
DOI: 10.2196/21816
11/2020

Dynamic deformation of the femoral head occurs on weightbearing in Legg-Calves-Perthes disease
Bone & Joint Open
Alexander Aarvold and Ryan Lohre and Harpreet Chhina and Kishore Mulpuri and Anthony Cooper
DOI: 10.1302/2046-3758.17.bjo-2020-0030.r1
07/2020

Dynamic deformation of the femoral head occurs on weightbearing in Legg-Calves-Perthes disease: a translational pilot study.
Bone & joint open
Aarvold A and Lohre R and Chhina H and Mulpuri K and Cooper A
DOI: 10.1302/2633-1462.17.bjo-2020-0030.r1
PubMed: 33215126
07/2020

Methodological Challenges in Investigating Supracondylar Fractures of the Humerus From a Child’s Viewpoint: Evolution of Study Protocol (Preprint)
Brittany Tara Lim and Harpreet Chhina and Ian Pike and Mariana Brussoni and Anthony Cooper
DOI: 10.2196/preprints.21816
06/2020

Modernization of bone age assessment: comparing the accuracy and reliability of an artificial intelligence algorithm and shorthand bone age to Greulich and Pyle
Skeletal Radiology
Gerges, M. and Eng, H. and Chhina, H. and Cooper, A.
DOI: 10.1007/s00256-020-03429-5
2020

Dynamic deformation of the femoral head occurs on weightbearing in Legg-Calves-Perthes disease a translational pilot study
Bone and Joint Open
Aarvold, A. and Lohre, R. and Chhina, H. and Mulpuri, K. and Cooper, A.
DOI: 10.1302/2633-1462.17.BJO-2020-0030.R1
2020

What matters to children with lower limb deformities; an international qualitative study informing the development of LIMB-Q Kids
Quality of Life Research
10/2019

International multiphase mixed methods study protocol to develop a patient-reported outcome instrument for children and adolescents with lower limb deformities.
BMJ open
Chhina H and Klassen A and Kopec JA and Oliffe J and Cooper A
DOI: 10.1136/bmjopen-2018-027079
PubMed: 31061048
05/2019

Support, information, and integration of genetics for children with congenital lower limb deficiencies in British Columbia, Canada
Paediatrics and Child Health (Canada)
Campbell, T. and Chen, C.-Y. and Chhina, H. and Chahal, R. and Cooper, A. and Elliott, A.M.
DOI: 10.1093/pch/pxz001
2019

Automated dynamic 3D ultrasound assessment of developmental dysplasia of the infant Hip
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Paserin, O. and Mulpuri, K. and Cooper, A. and Hodgson, A.J. and Garbi, R.
DOI: 10.1007/978-3-030-11166-3_12
2019

Assessing the reliability of the modified gartland classification system for extension-type supracondylar humerus fractures
Journal of Children's Orthopaedics
Teo, T.L. and Schaeffer, E.K. and Habib, E. and Cherukupalli, A. and Cooper, A.P. and Aroojis, A. and Sankar, W.N. and Upasani, V.V. and Carsen, S. and Mulpuri, K. and Reilly, C.
DOI: 10.1302/1863-2548.13.190005
2019

Real Time RNN Based 3D Ultrasound Scan Adequacy for Developmental Dysplasia of the Hip
Medical Image Computing and Computer Assisted Intervention – MICCAI 2018
Olivia Paserin and Kishore Mulpuri and Anthony Cooper and Antony J. Hodgson and Rafeef Garbi
DOI: 10.1007/978-3-030-00928-1_42
09/2018

Do Immediate Postoperative Radiographs Change Patient Management After Fracture Fixation? A Systematic Review
Journal of Orthopaedic Trauma
Tammie Teo and Emily Schaeffer and Anthony Cooper and Kishore Mulpuri
DOI: 10.1097/bot.0000000000001152
05/2018

Southwick angle measurements and SCFE slip severity classifications are affected by frog-lateral positioning.
Skeletal radiology
DOI: 10.1007/s00256-017-2761-z
PubMed: 28840319
01/2018

Do Immediate Postoperative Radiographs Change Patient Management after Fracture Fixation? A Systematic Review
Journal of Orthopaedic Trauma
Teo, T. and Schaeffer, E. and Cooper, A. and Mulpuri, K.
DOI: 10.1097/BOT.0000000000001152
2018

Inter- and Intra-observer reliability of the pixel value ratio, Ru Li's and Donnan's classifications of regenerate quality in pediatric limb lengthening
Journal of Limb Lengthening & Reconstruction
DOI: 10.4103/jllr.jllr_11_17
2018

Comparison of self-reports and parent proxy-reports on the quality of life and function of children with lower limb deformities
Quality of Life Research
10/2017

Qualitative Insights to Health Related Quality Of Life among US and Canadian based Children with Lower Limb Deformities
Quality of Life Research
10/2017

Relationships Between Severity of Deformity and Impingement in Slipped Capital Femoral Epiphysis.
Journal of pediatric orthopedics
DOI: 10.1097/bpo.0000000000000641
PubMed: 26356312
06/2017

Quality of life of children with lower limb deformities: A systematic review of patient-reported outcomes and development of a preliminary conceptual framework
Journal of Limb Lengthening & Reconstruction
Anthony Cooper and Harpreet Chhina and Anne Klassen and Jacek Kopec and Sujin Park and Cadi Fortes
DOI: 10.4103/jllr.jllr_33_16
2017

Automatic Near Real-Time Evaluation of 3D Ultrasound Scan Adequacy for Developmental Dysplasia of the Hip
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Paserin, O. and Mulpuri, K. and Cooper, A. and Hodgson, A.J. and Abugharbieh, R.
DOI: 10.1007/978-3-319-67543-5_12
2017

Relationships between Severity of Deformity and Impingement in Slipped Capital Femoral Epiphysis
Journal of Pediatric Orthopaedics
Jones, C.E. and Cooper, A.P. and Doucette, J. and Buchan, L.L. and Wilson, D.R. and Mulpuri, K. and D'Entremont, A.G.
DOI: 10.1097/BPO.0000000000000641
2017

A 3D femoral head coverage metric for enhanced reliability in diagnosing hip dysplasia
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Quader, N. and Hodgson, A.J. and Mulpuri, K. and Cooper, A. and Abugharbieh, R.
DOI: 10.1007/978-3-319-66182-7_12
2017

Quantifying Dynamic Assessment of Developmental Dysplasia of the Hip
Journal of Bone and Joint Surgery
DOI: 10.29007/zh41
2017

Automatic evaluation of scan adequacy and dysplasia metrics in 2D ultrasound images of the neonatal hip
The Bone & Joint Journal
12/2016

Evidence-Based Treatment for Congenital Femoral Deficiency
Paediatric Orthopaedics
Anthony Cooper and James A. Fernandes
DOI: 10.1007/978-3-319-41142-2_7
11/2016

Development of a patient-reported outcome instrument to measure quality of life of children with lower limb deformities: preliminary results
Quality of Life Research
10/2016

Standing weight bearing MRI for evaluation of Legg-Calvé-Perthes disease: a pilot study
Journal of Bone and Joint Surgery
09/2016

A Reliable Automatic 2D Measurement for Developmental Dysplasia of the Hip
Journal of Bone and Joint Surgery
04/2016

Arthroscopic treatment of femoroacetabular impingement following slipped capital femoral epiphysis.
The bone & joint journal
DOI: 10.1302/0301-620x.98b1.35831
PubMed: 26733511
01/2016

Lower limb deficiency syndromes
Orthopaedics and Trauma
Anthony Cooper and James A. Fernandes
DOI: 10.1016/j.mporth.2016.09.007
2016

Arthroscopic treatment of femoroacetabular impingement following slipped capital femoral epiphysis
Bone and Joint Journal
Basheer, S.Z. and Cooper, A.P. and Maheshwari, R. and Balakumar, B. and Madan, S.
DOI: 10.1302/0301-620X.98B1.35831
2016

Towards reliable automatic characterization of neonatal hip dysplasia from 3D ultrasound images
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Quader, N. and Hodgson, A. and Mulpuri, K. and Cooper, A. and Abugharbieh, R.
DOI: 10.1007/978-3-319-46720-7_70
2016

Management of displaced supracondylar fractures of the humerus using lateral versus cross k wires: a prospective randomised trial
Journal of Bone and Joint Surgery
2016

What clinimetric evidence exists for using hip-specific patient-reported outcome measures in pediatric hip impingement?
Clinical Orthopaedics and Related Research
DOI: 10.1007/s11999-014-4027-6
PubMed: 25367111
04/2015

Correction of Genu Recurvatum Deformity Using a Hexapod Frame: A Case Series and Review of the Literature
Journal of Contemporary Dental Practice
Johnson, L. and McCammon, J. and Cooper, A.
DOI: 10.5005/jp-journals-10080-1528
2015

The Multiplier Method for Predicting Limb Length Discrepancy in Patients with Vascular Anomalies in the Lower Limb
Journal of Limb Lengthening and Reconstruction
2015

A novel method for assessing postoperative femoral head reduction in developmental dysplasia of the hip.
Journal of children's orthopaedics
DOI: 10.1007/s11832-014-0600-5
PubMed: 24993902
08/2014

Evidence-based management of developmental dysplasia of the hip.
The Orthopedic clinics of North America
DOI: 10.1016/j.ocl.2014.03.005
PubMed: 24975762
07/2014

The contralateral foot in children with unilateral clubfoot, is the unaffected side normal?
Gait & posture
DOI: 10.1016/j.gaitpost.2014.05.004
PubMed: 25001577
07/2014

The oblique plane deformity in slipped capital femoral epiphysis.
Journal of children's orthopaedics
DOI: 10.1007/s11832-014-0559-2
PubMed: 24554127
03/2014

Foot disorders in childhood
Surgery (Oxford)
Anthony Cooper and Stanley Jones
DOI: 10.1016/j.mpsur.2013.11.004
01/2014

Foot and Ankle
Postgraduate Paediatric Orthopaedics
Anthony Cooper and Stan Jones
DOI: 10.1007/9781107415065
2014

Rotator cuff tears
Surgery (Oxford)
Anthony Cooper and Amjid Ali
DOI: 10.1016/j.mpsur.2013.01.017
04/2013

The treatment of severe slipped capital femoral epiphysis via the Ganz surgical dislocation and anatomical reduction: a prospective study.
The bone & joint journal
DOI: 10.1302/0301-620x.95b3.30113
PubMed: 23450032
03/2013

Outcomes of hip arthroscopy. A prospective analysis and comparison between patients under 25 and over 25 years of age.
British journal of sports medicine
DOI: 10.1136/bjsports-2012-091028
PubMed: 22797420
03/2013

The treatment of severe slipped capital femoral epiphysis via the Ganz surgical dislocation and anatomical reduction: A prospective study
Journal of Bone and Joint Surgery - Series B
Madan, S.S. and Cooper, A.P. and Davies, A.G. and Fernandes, J.A.
DOI: 10.1302/0301-620X.95B3
2013

Redislocation and the computerised tomography evaluation of developmental dysplasia of the hip
Journal of Bone and Joint Surgery
2012

Service Evaluation of Work Performed by Non-Consultant-Grade Doctors at Night
The Bulletin of the Royal College of Surgeons of England
K Hassan and L McGrath and K Thomas and L Henderson and S Thangiaraj and A Kocheta and B Wilson and S Royston and A Cooper
DOI: 10.1308/147363510x514154
07/2010

Routine intra-operative microbiological samples in direct exchanges of total hip replacements. A retrospective analysis of 100 consecutive cases with minimum 1 year follow up
Journal of Bone and Joint Surgery
2010

Voriconazole-impregnated beads in the treatment of candidal prosthetic joint infection
Clinical Microbiology and Infection
04/2009

A rare example of pseudodislocation of the acromioclavicular joint in a 12 year old boy
Journal of Orthopaedics
2008

The foot and ankle
Postgraduate Paediatric Orthopaedics
Anthony Cooper and Stan Jones
DOI: 10.1017/cbo9781107415065.008

Research

Preventative Multimodal Analgesia for Children Undergoing Lower Limb Reconstruction with External Fixators: A Prospective Study of Postoperative Pain
Objective: To assess the peri-operative analgesia regimen that has been previously developed for children undergoing limb reconstruction surgery at BC Children’s Hospital, during the acute and long-term post-operative recovery phase. This study is being conducted in collaboration with the Department of Anesthesiology, Pharmacology & Therapeutics.

Multicentre Pin Site Infection Study
Objective: To measure and document pin site infection rate and pin site care across Canada, US and UK through a multi-centre pin site infection database. This study involving ten surgeons (BCCH being the primary site) across various sites will provide important information for limb lengthening and reconstruction services across the world, as well as parents/primary caregivers of children in external fixation devices (EFDs). By identifying the factors contributing to pin site infections, this study will take another step towards improving clinical care for children in EFDs.

Health-related Quality of Life in Children with Lower Limb Deficiency
Objectives: a) To develop and validate a patient-reported quality of life tool for children with lower limb deficiency; b) To establish the baseline health-related quality of life in these children using the newly developed tool; c) To investigate the quality of life of caregivers of children with lower limb deficiency.

Grants

Title

Development of a Patient Reported Quality of Life Questionnaire for Children with Lower Limb Deformities Funding Agency

Canadian Orthopaedic Research Legacy (CORL) Year

2017-2019

Title

Evaluating the Accuracy of the Paley Multiplier Method for Predicting Limb Length Discrepancy in Populations with Vascular Anomalies Funding Agency

UBC Plastic Surgery Academic Grant Year

2016-2017

Title

Paediatric Limb Reconstruction Funding Agency

CFRI Investigator Grant Award Program (IGAP) Year

2016-2021

Honours & Awards

Getty Plate for best academic project 2011 (Runner up)

Investigator Grant Award, CFRI, 2016

Limb Lengthening and Reconstruction Society Traveling Fellowship, 2016

Research Group Members

Taqdir Ali, Postdoctoral Fellow
Yumi Chang, Admin Coordinator, Academic Coordinator
Harpreet Chhina, Research Associate
Sophie Davidson, Research Assistant
Emily Dunnion
Tara Gholamian, Research Assistant
Mina Han, Research Assistant
Brittany Lim, Research Asisstant
Tuguldur Lkhagva, Research Assistant
Aidan Loh, Research Assistant
Maitri Panchal
Ryanne Uy, Research Assistant