Overview

As a pediatric electrophysiologist, my research focuses on the rhythm of the heart. Disturbances in the rhythm of the heart, or arrhythmias, can occur in otherwise healthy children or in children with heart disease. My research aims to improve the outcome of children who have arrhythmias.

Many potentially lethal conditions affecting the heart rhythm are inherited and I work on heritable conditions causing arrhythmias. This research involves collaborations with clinician and basic scientists from all over the world to improve our understanding of inherited heart rhythm disorders.

Publications

RYR2-ryanodinopathies: from calcium overload to calcium deficiency
Europace
Christian Steinberg and Thomas M Roston and Christian van der Werf and Shubhayan Sanatani and S R Wayne Chen and Arthur A M Wilde and Andrew D Krahn
DOI: 10.1093/europace/euad156
06/2023

Identification and in-silico characterization of splice-site variants from a large cardiogenetic national registry
European Journal of Human Genetics
DOI: 10.1038/s41431-022-01193-9
2023

Increased Ca2+Transient Underlies RyR2-Related Left Ventricular Noncompaction
Circulation Research
DOI: 10.1161/CIRCRESAHA.123.322504
2023

Patterns of Electrocardiographic Abnormalities in Children with Hypertrophic Cardiomyopathy
Pediatric Cardiology
DOI: 10.1007/s00246-023-03252-4
2023

The safety of sports in children with inherited arrhythmia substrates
Frontiers in Pediatrics
DOI: 10.3389/fped.2023.1151286
2023

Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C+/- During Development
bioRxiv
DOI: 10.1101/2023.06.06.542948
2023

The Prevalence and Characteristics of Arrhythmic Mitral Valve Prolapse in Patients With Unexplained Cardiac Arrest
JACC: Clinical Electrophysiology
DOI: 10.1016/j.jacep.2023.08.017
2023

Transseptal puncture during catheter ablation associated with higher radiation exposure
Cardiology in the young
DOI: 10.1017/S1047951122001676
2023

Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation
bioRxiv
DOI: 10.1101/2023.03.02.530843
2023

The 2023 Canadian Cardiovascular Society Clinical Practice Update on Management of the Patient With a Prolonged QT Interval
Canadian Journal of Cardiology
DOI: 10.1016/j.cjca.2023.06.011
2023

Calcium Release Deficiency Syndrome: A New Inherited Arrhythmia Syndrome
Cardiac Electrophysiology Clinics
DOI: 10.1016/j.ccep.2023.05.003
2023

Management of Inherited Arrhythmia Syndromes: A HiRO Consensus Handbook on Process of Care
CJC Open
DOI: 10.1016/j.cjco.2023.02.006
2023

The Association Between Congenital Heart Disease and Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
Pediatric Cardiology
DOI: 10.1007/s00246-023-03146-5
2023

Advancing the science of management of arrhythmic disease in children and adult congenital heart disease patients within the last 25 years
Europace
DOI: 10.1093/europace/euad155
2023

Incremental value of the signal-averaged ECG for diagnosing arrhythmogenic cardiomyopathy
Heart Rhythm
Pearman, C.M. and Lee, D. and Davies, B. and Khan, H. and Tadros, R. and Cadrin-Tourigny, J. and Roberts, J.D. and Sanatani, S. and Simpson, C. and Angaran, P. and Hansom, S. and Ilhan, E. and Seifer, C. and Green, M. and Gardner, M. and Talajic, M. and Laksman, Z. and Healey, J.S. and Krahn, A.D.
DOI: 10.1016/j.hrthm.2022.10.005
2023

High Prevalence of Neurodevelopmental Disorders in Pediatric Long QT Syndrome: A Single Centre Experience
Shubhayan Sanatani and Avani Lamba and Dania Kallas and Sophia Gu and Sanjana Singh and Sonia Franciosi
DOI: 10.22541/au.166917247.72370129/v1
11/2022

Importance of genetic testing in unexplained cardiac arrest
European Heart Journal
Steffany Grondin and Brianna Davies and Julia Cadrin-Tourigny and Christian Steinberg and Christopher C Cheung and Paloma Jorda and Jeffrey S Healey and Martin S Green and Shubhayan Sanatani and Wael Alqarawi and Paul Angaran and Laura Arbour and Pavel Antiperovitch and Habib Khan and Richard Leather and Peter G Guerra and Lena Rivard and Christopher S Simpson and Martin Gardner and Ciorsti MacIntyre and Colette Seifer and Anne Fournier and Jacqueline Joza and Michael H Gollob and Guillaume Lettre and Mario Talajic and Zachary W Laksman and Jason D Roberts and Andrew D Krahn and Rafik Tadros
DOI: 10.1093/eurheartj/ehac145
08/2022

An International Multicenter Cohort Study on ß-Blockers for the Treatment of Symptomatic Children With Catecholaminergic Polymorphic Ventricular Tachycardia
Circulation
Peltenburg, P.J. and Kallas, D. and Bos, J.M. and Lieve, K.V.V. and Franciosi, S. and Roston, T.M. and Denjoy, I. and Sorensen, K.B. and Ohno, S. and Roses-Noguer, F. and Aiba, T. and Maltret, A. and Lapage, M.J. and Atallah, J. and Giudicessi, J.R. and Clur, S.-A.B. and Blom, N.A. and Tanck, M. and Extramiana, F. and Kato, K. and Barc, J. and Borggrefe, M. and Behr, E.R. and Sarquella-Brugada, G. and Tfelt-Hansen, J. and Zorio, E. and Swan, H. and Kammeraad, J.A.E. and Krahn, A.D. and Davis, A. and Sacher, F. and Schwartz, P.J. and Roberts, J.D. and Skinner, J.R. and Van Den Berg, M.P. and Kannankeril, P.J. and Drago, F. and Robyns, T. and Haugaa, K. and Tavacova, T. and Semsarian, C. and Till, J. and Probst, V. and Brugada, R. and Shimizu, W. and Horie, M. and Leenhardt, A. and Ackerman, M.J. and Sanatani, S. and Van Der Werf, C. and Wilde, A.A.M.
DOI: 10.1161/CIRCULATIONAHA.121.056018
2022

Faintly tired: a systematic review of fatigue in patients with orthostatic syncope
Clinical Autonomic Research
Wu, R.E.Y. and Khan, F.M. and Hockin, B.C.D. and Lobban, T.C.A. and Sanatani, S. and Claydon, V.E.
DOI: 10.1007/s10286-022-00868-z
2022

Anticoagulation management and risk of thromboembolism in healthy youth with atrial fibrillation: Data from a multi-institutional PACES collaborative registry
Heart Rhythm
El Assaad, I. and Hammond, B.H. and Aziz, P.F. and Janson, C. and Sherwin, E.D. and Stephenson, E.A. and Johnsrude, C.L. and Niu, M. and Shetty, I. and Lawrence, D. and McCanta, A.C. and Balaji, S. and Sanatani, S. and Fish, F. and Webster, G.
DOI: 10.1016/j.hrthm.2022.07.018
2022

Pediatric and adult Out-of-Hospital cardiac arrest incidence within and near public schools in British Columbia: Missed opportunities for Systematic AED deployment strategies
Resuscitation
Liang, L.D. and Leung, K.H.B. and Chan, T.C.Y. and Deakin, J. and Heidet, M. and Meckler, G. and Scheuermeyer, F. and Sanatani, S. and Christenson, J. and Grunau, B.
DOI: 10.1016/j.resuscitation.2022.09.020
2022

Sex Differences and Utility of Treadmill Testing in Long-QT Syndrome
Journal of the American Heart Association
Yee, L.A. and Han, H.-C. and Davies, B. and Pearman, C.M. and Laksman, Z.W.M. and Roberts, J.D. and Steinberg, C. and Tadros, R. and Cadrin-Tourigny, J. and Simpson, C.S. and Gardner, M. and Macintyre, C. and Arbour, L. and Leather, R. and Fournier, A. and Green, M.S. and Kimber, S. and Angaran, P. and Sanatani, S. and Joza, J. and Khan, H. and Healey, J.S. and Atallah, J. and Seifer, C. and Krahn, A.D.
DOI: 10.1161/JAHA.121.025108
2022

A dangerous dance: Recurrent cardiac crises in TANGO2-deficiency disorder
Heart Rhythm
Roston, T.M. and Sanatani, S.
DOI: 10.1016/j.hrthm.2022.05.030
2022

A Global Look to the Future of Pediatric Electrophysiology
JACC: Clinical Electrophysiology
Cohen, M.I. and Dubin, A.M. and Webster, G. and Bar-Cohen, Y. and Motonaga, K.S. and Kriebel, T. and Sanatani, S. and Rosenthal, E. and Moltedo, J. and Yoshimoto, J. and Davis, A. and Van Hare, G.F. and Etheridge, S.P.
DOI: 10.1016/j.jacep.2022.09.015
2022

Life-threatening cardiac arrhythmia and sudden death during electronic gaming: An international case series and systematic review
Heart Rhythm
Lawley, C.M. and Tester, M. and Sanatani, S. and Prendiville, T. and Beach, C.M. and Vinocur, J.M. and Horie, M. and Uhm, J.-S. and Khongphatthanayothin, A. and Ayers, M.D. and Starling, L. and Yoshida, Y. and Shah, M.J. and Skinner, J.R. and Turner, C.
DOI: 10.1016/j.hrthm.2022.08.003
2022

Familial Recurrence Patterns in Congenitally Corrected Transposition of the Great Arteries: An International Study
Circulation: Genomic and Precision Medicine
Tortigue, M. and Nield, L.E. and Karakachoff, M. and McLeod, C.J. and Belli, E. and Babu-Narayan, S.V. and Prigent, S. and Boet, A. and Conway, M. and Elder, R.W. and Ladouceur, M. and Khairy, P. and Kowalik, E. and Kalfa, D.M. and Barron, D.J. and Mussa, S. and Hiippala, A. and Temple, J. and Abadir, S. and Le Gloan, L. and Lachaud, M. and Sanatani, S. and Thambo, J.-B. and Gronier, C.G. and Amedro, P. and Vaksmann, G. and Charbonneau, A. and Koutbi, L. and Ovaert, C. and Houeijeh, A. and Combes, N. and Maury, P. and Duthoit, G. and Hiel, B. and Erickson, C.C. and Bonnet, C. and Van Hare, G.F. and Dina, C. and Karsenty, C. and Fournier, E. and Le Bloa, M. and Pass, R.H. and Liberman, L. and Happonen, J.-M. and Perry, J.C. and Romefort, B. and Benbrik, N. and Hauet, Q. and Fraisse, A. and Gatzoulis, M.A. and Abrams, D.J. and Dubin, A.M. and Ho, S.Y. and Redon, R. and Bacha, E.A. and Schott, J.-J. and Baruteau, A.-E.
DOI: 10.1161/CIRCGEN.121.003464
2022

One family's clinical odyssey from evolving phenotypic and genotypic knowledge of catecholaminergic polymorphic ventricular tachycardia and long QT syndrome
HeartRhythm Case Reports
Johnsrude, C.L. and Roberts, J.D. and Roston, T.M. and Russell, B. and Franciosi, S. and Sanatani, S.
DOI: 10.1016/j.hrcr.2022.07.006
2022

Correction to: Faintly tired: a systematic review of fatigue in patients with orthostatic syncope (Clinical Autonomic Research, (2022), 32, 3, (185-203), 10.1007/s10286-022-00868-z)
Clinical Autonomic Research
Wu, R.E.Y. and Khan, F.M. and Hockin, B.C.D. and Lobban, T.C.A. and Sanatani, S. and Claydon, V.E.
DOI: 10.1007/s10286-022-00886-x
2022

Return of Results Policies for Genomic Research: Current Practices and the Hearts in Rhythm Organization (HiRO) Approach
Canadian Journal of Cardiology
Comber, D.A. and Davies, B. and Roberts, J.D. and Tadros, R. and Green, M.S. and Healey, J.S. and Simpson, C.S. and Sanatani, S. and Steinberg, C. and MacIntyre, C. and Angaran, P. and Duff, H. and Hamilton, R. and Arbour, L. and Leather, R. and Seifer, C. and Fournier, A. and Atallah, J. and Kimber, S. and Makanjee, B. and Alqarawi, W. and Cadrin-Tourigny, J. and Joza, J. and Gibbs, K. and Robb, L. and Zahavich, L. and Gardner, M. and Talajic, M. and Virani, A. and Krahn, A.D. and Lehman, A. and Laksman, Z.W.M.
DOI: 10.1016/j.cjca.2021.10.006
2022

A Population-Based Study of Unexplained/Lone Atrial Fibrillation: Temporal Trends, Management, and Outcomes
CJC Open
Roston, T.M. and Islam, S. and Hawkins, N.M. and Laksman, Z.W. and Sanatani, S. and Krahn, A.D. and Sandhu, R. and Kaul, P.
DOI: 10.1016/j.cjco.2021.09.006
2022

Electrocardiogram in pediatric syncope
Pediatric Emergency Care
Manouzi, A. and Sanatani, S. and Doan, Q.
DOI: 10.1097/PEC.0000000000002469
2022

When Adenosine Does Not Work: Apparent and Real Adenosine-Resistant Tachycardia
Pediatric emergency care
Shortland, J. and Saravu Vijayashankar, S. and Sanatani, S.
DOI: 10.1097/PEC.0000000000002701
2022

Clinical and Functional Characterization of Ryanodine Receptor 2 Variants Implicated in Calcium-Release Deficiency Syndrome
JAMA Cardiology
Roston, T.M. and Wei, J. and Guo, W. and Li, Y. and Zhong, X. and Wang, R. and Estillore, J.P. and Peltenburg, P.J. and Noguer, F.R.I. and Till, J. and Eckhardt, L.L. and Orland, K.M. and Hamilton, R. and Lapage, M.J. and Krahn, A.D. and Tadros, R. and Vinocur, J.M. and Kallas, D. and Franciosi, S. and Roberts, J.D. and Wilde, A.A.M. and Jensen, H.K. and Sanatani, S. and Chen, S.R.W.
DOI: 10.1001/jamacardio.2021.4458
2022

A pharmacogenomic investigation of the cardiac safety profile of ondansetron in children and pregnant women
Biomedicine and Pharmacotherapy
Drögemöller, B.I. and Wright, G.E.B. and Trueman, J. and Shaw, K. and Staub, M. and Chaudhry, S. and Miao, F. and Higginson, M. and Groeneweg, G.S.S. and Brown, J. and Magee, L.A. and Whyte, S.D. and West, N. and Brodie, S.M. and Jong, G.?. and Israels, S. and Berger, H. and Ito, S. and Rassekh, S.R. and Sanatani, S. and Ross, C.J.D. and Carleton, B.C.
DOI: 10.1016/j.biopha.2022.112684
2022

Human RyR2 (Ryanodine Receptor 2) Loss-of-Function Mutations
Circulation: Arrhythmia and Electrophysiology
Yanhui Li and Jinhong Wei and Wenting Guo and Bo Sun and John Paul Estillore and Ruiwu Wang and Ayhan Yoruk and Thomas M. Roston and Shubhayan Sanatani and Arthur A.M. Wilde and Michael H. Gollob and Jason D. Roberts and Zian H. Tseng and Henrik K. Jensen and S.R. Wayne Chen
DOI: 10.1161/CIRCEP.121.010013
09/2021

Variant Reinterpretation in Survivors of Cardiac Arrest With Preserved Ejection Fraction (the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry) by Clinicians and Clinical Commercial Laboratories
Circulation: Genomic and Precision Medicine
Brianna Davies and Kirsten Bartels and Julie Hathaway and Fang Xu and Jason D. Roberts and Rafik Tadros and Martin S. Green and Jeffrey S. Healey and Christopher S. Simpson and Shubhayan Sanatani and Christian Steinberg and Martin Gardner and Paul Angaran and Mario Talajic and Robert Hamilton and Laura Arbour and Colette Seifer and Anne Fournier and Jacqueline Joza and Andrew D. Krahn and Anna Lehman and Zachary W.M. Laksman
DOI: 10.1161/CIRCGEN.120.003235
06/2021

Intermediate-coupled premature ventricular complexes and ventricular tachycardia during exercise recovery
HeartRhythm Case Reports
Christopher O.Y. Li and Sonia Franciosi and Marc W. Deyell and Shubhayan Sanatani
DOI: 10.1016/j.hrcr.2020.11.001
02/2021

Potential overdiagnosis of long QT syndrome using exercise stress and QT stand testing in children and adolescents with a low probability of disease
Journal of Cardiovascular Electrophysiology
Thomas M. Roston and Astrid M. De Souza and Hilary V. Romans and Sonia Franciosi and Kathryn R. Armstrong and Shubhayan Sanatani
DOI: 10.1111/jce.14865
02/2021

Evaluation of conventional troponin I testing for the detection of myocardial dysfunction in children
Paediatrics and Child Health (Canada)
Mcgovern, E. and Voss, C. and Hemphill, N.M. and Sanatani, S. and Barakauskas, V. and Harris, K.C.
DOI: 10.1093/pch/pxaa011
2021

Paediatric supraventricular tachycardia patients potentially more at risk of developing psychological difficulties compared to healthy peers
Acta Paediatrica, International Journal of Paediatrics
Tester, M.A. and Riehm, K.E. and Perry, F. and Franciosi, S. and Escudero, C.A. and Maghrabi, K. and Sneddon, P. and Sanatani, S.
DOI: 10.1111/apa.15556
2021

Burst Exercise Testing Can Unmask Arrhythmias in Patients With Incompletely Penetrant Catecholaminergic Polymorphic Ventricular Tachycardia
JACC: Clinical Electrophysiology
Roston, T.M. and Kallas, D. and Davies, B. and Franciosi, S. and De Souza, A.M. and Laksman, Z.W. and Sanatani, S. and Krahn, A.D.
DOI: 10.1016/j.jacep.2021.02.013
2021

Evaluation of age at symptom onset, proband status, and sex as predictors of disease severity in pediatric catecholaminergic polymorphic ventricular tachycardia
Heart Rhythm
Kallas, D. and Roston, T.M. and Franciosi, S. and Brett, L. and Lieve, K.V.V. and Kwok, S.-Y. and Kannankeril, P.J. and Krahn, A.D. and LaPage, M.J. and Etheridge, S. and Hill, A. and Johnsrude, C. and Perry, J. and Knight, L. and Fischbach, P. and Balaji, S. and Tisma-Dupanovic, S. and Law, I. and Atallah, J. and Backhoff, D. and Kamp, A. and Kubus, P. and Kean, A. and Aziz, P.F. and Kovach, J. and Lau, Y. and Kron, J. and Clur, S.-A. and Sarquella-Brugada, G. and Wilde, A.A.M. and Sanatani, S.
DOI: 10.1016/j.hrthm.2021.07.061
2021

Short-coupled ventricular fibrillation represents a distinct phenotype among latent causes of unexplained cardiac arrest: A report from the CASPER registry
European Heart Journal
Steinberg, C. and Davies, B. and Mellor, G. and Tadros, R. and Laksman, Z.W. and Roberts, J.D. and Green, M. and Alqarawi, W. and Angaran, P. and Healey, J. and Sanatani, S. and Leather, R. and Seifer, C. and Fournier, A. and Duff, H. and Gardner, M. and McIntyre, C. and Hamilton, R. and Simpson, C.S. and Krahn, A.D.
DOI: 10.1093/eurheartj/ehab275
2021

Management and outcomes of atrial fibrillation in 241 healthy children and young adults: Revisiting “lone” atrial fibrillation—A multi-institutional PACES collaborative study
Heart Rhythm
El Assaad, I. and Hammond, B.H. and Kost, L.D. and Worley, S. and Janson, C.M. and Sherwin, E.D. and Stephenson, E.A. and Johnsrude, C.L. and Niu, M. and Shetty, I. and Lawrence, D. and McCanta, A.C. and Balaji, S. and Sanatani, S. and Fish, F. and Webster, G. and Aziz, P.F.
DOI: 10.1016/j.hrthm.2021.07.066
2021

Potential Role of Life Stress in Unexplained Sudden Cardiac Arrest
CJC Open
Chang Liu, M. and Tester, M.A. and Franciosi, S. and Krahn, A.D. and Gardner, M.J. and Roberts, J.D. and Sanatani, S.
DOI: 10.1016/j.cjco.2020.10.016
2021

Pediatric catecholaminergic polymorphic ventricular tachycardia: A translational perspective for the clinician-scientist
International Journal of Molecular Sciences
Kallas, D. and Lamba, A. and Roston, T.M. and Arslanova, A. and Franciosi, S. and Tibbits, G.F. and Sanatani, S.
DOI: 10.3390/ijms22179293
2021

Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia
Current Protocols
Arslanova, A. and Shafaattalab, S. and Ye, K. and Asghari, P. and Lin, L. and Kim, B. and Roston, T.M. and Hove-Madsen, L. and Van Petegem, F. and Sanatani, S. and Moore, E. and Lynn, F. and S?ndergaard, M. and Luo, Y. and Chen, S.R.W. and Tibbits, G.F.
DOI: 10.1002/cpz1.320
2021

Hyperthyroidism With Atrial Fibrillation in Children: A Case Report and Review of the Literature
Frontiers in Endocrinology
Subramonian, D. and Wu, Y.J. and Amed, S. and Sanatani, S.
DOI: 10.3389/fendo.2021.689497
2021

At-home determination of 24-h urine sodium excretion: Validation of chloride test strips and multiple spot samples
Autonomic Neuroscience: Basic and Clinical
Heeney, N.D. and Lee, R.H. and Hockin, B.C.D. and Clarke, D.C. and Sanatani, S. and Armstrong, K. and Sedlak, T. and Claydon, V.E.
DOI: 10.1016/j.autneu.2021.102797
2021

When the blood pressure misleads you: A diagnostic conundrum in an unusual case of coarctation
Congenital Heart Disease
Kapravelou, E. and Issa, H. and Culham, G. and Hosking, M. and Gandhi, S.K. and Sanatani, S.
DOI: 10.32604/CHD.2021.016548
2021

Cardiac ryanodine receptor calcium release deficiency syndrome
Science Translational Medicine
Sun, B. and Yao, J. and Ni, M. and Wei, J. and Zhong, X. and Guo, W. and Zhang, L. and Wang, R. and Belke, D. and Chen, Y.-X. and Lieve, K.V.V. and Broendberg, A.K. and Roston, T.M. and Blankoff, I. and Kammeraad, J.A. and Von Alvensleben, J.C. and Lazarte, J. and Vallmitjana, A. and Bohne, L.J. and Rose, R.A. and Benitez, R. and Hove-Madsen, L. and Napolitano, C. and Hegele, R.A. and Fill, M. and Sanatani, S. and Wilde, A.A.M. and Roberts, J.D. and Priori, S.G. and Jensen, H.K. and Chen, S.R.W.
DOI: 10.1126/scitranslmed.aba7287
2021

To play or not to play? sports participation and shared decision-making in athletes with inherited heart rhythm disorders
British Journal of Sports Medicine
Christopher OY Li and Thomas M Roston and Claire MacEwing and Shubhayan Sanatani
DOI: 10.1136/bjsports-2019-101236
10/2020

Genotype Predicts Outcomes in Fetuses and Neonates With Severe Congenital Long QT Syndrome.
JACC. Clinical electrophysiology
Moore JP and Gallotti RG and Shannon KM and Bos JM and Sadeghi E and Strasburger JF and Wakai RT and Horigome H and Clur SA and Hill AC and Shah MJ and Behere S and Sarquella-Brugada G and Ackerman MJ
DOI: 10.1016/j.jacep.2020.06.001
PubMed: 33213816
08/2020

An International Multi-Center Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2- Catecholaminergic Polymorphic Ventricular Tachycardia.
Circulation
Ng K and Titus EW and Lieve KV and Roston TM and Mazzanti A and Deiter FH and Denjoy I and Ingles J and Till J and Robyns T and Connors SP and Steinberg C and Abrams DJ and Pang B and Roberts JD
DOI: 10.1161/circulationaha.120.045723
PubMed: 32693635
07/2020

Loss of ventricular preexcitation during noninvasive testing does not exclude high-risk accessory pathways: A multicenter study of WPW in children.
Heart rhythm
Escudero CA and Ceresnak SR and Collins KK and Pass RH and Aziz PF and Blaufox AD and Ortega MC and Cannon BC and Cohen M and Dechert BE and Dubin AM and Motonaga KS and Epstein MR and Janson C
DOI: 10.1016/j.hrthm.2020.05.035
PubMed: 32497761
06/2020

The Hearts in Rhythm Organization: A Canadian National Cardiogenetics Network.
CJC open
Davies B and Roberts JD and Tadros R and Green MS and Healey JS and Simpson CS and Sanatani S and Steinberg C and MacIntyre C and Angaran P and Duff H and Hamilton R and Arbour L and Krahn AD
DOI: 10.1016/j.cjco.2020.05.006
PubMed: 33305225
05/2020

Accelerated Idioventricular Rhythm in Inflammatory Bowel Disease: When the Gut Takes Charge
CJC open
Vijayashankar S and Barker C and Sanatani S
05/2020

Cardiac arrest in a mother and daughter and the identification of a novel RYR2 variant, predisposing to low penetrant catecholaminergic polymorphic ventricular tachycardia in a four-generation Canadian family
Molecular Genetics & Genomic Medicine
Matthew Tung and Filip Van Petegem and Samantha Lauson and Ashley Collier and Kathy Hodgkinson and Bridget Fernandez and Sean Connors and Rick Leather and Shubhayan Sanatani and Laura Arbour
DOI: 10.1002/mgg3.1151
04/2020

Difficulties with invasive risk stratification performed under anesthesia in pediatric Wolff-Parkinson-White Syndrome
Heart Rhythm
Mark H. Shwayder and Carolina A. Escudero and Susan P. Etheridge and Brynn E. Dechert and Ian H. Law and Andrew D. Blaufox and James C. Perry and Anne M. Dubin and Shubhayan Sanatani and Kathryn K. Collins
DOI: 10.1016/j.hrthm.2019.09.011
02/2020

Initially unexplained cardiac arrest in children and adolescents: A national experience from the Canadian Pediatric Heart Rhythm Network.
Heart rhythm
Cunningham T and Roston TM and Franciosi S and Liu MC and Atallah J and Escudero CA and Udupa S and Roberts JD and Dhillon S and Dallaire F and Fournier A and Fatah M and Hamilton R and Sanatani S
DOI: 10.1016/j.hrthm.2020.01.030
PubMed: 32036023
02/2020

Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia.
Circulation. Arrhythmia and electrophysiology
Lieve KVV and Dusi V and van der Werf C and Bos JM and Lane CM and Stokke MK and Roston TM and Djupsjöbacka A and Wada Y and Denjoy I and Bundgaard H and Noguer FRI and Semsarian C and Wilde AAM
DOI: 10.1161/circep.119.007471
PubMed: 32063070
02/2020

Accelerated Idioventricular Rhythm in Inflammatory Bowel Disease: When the Gut Takes Charge
CJC Open
Vijayashankar, S.S. and Barker, C. and Sanatani, S.
DOI: 10.1016/j.cjco.2020.04.013
2020

Heart Rate Recovery after Exercise Is Associated with Arrhythmic Events in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia
Circulation: Arrhythmia and Electrophysiology
Lieve, K.V.V. and Dusi, V. and Van Der Werf, C. and Bos, J.M. and Lane, C.M. and Stokke, M.K. and Roston, T.M. and Djupsjöbacka, A. and Wada, Y. and Denjoy, I. and Bundgaard, H. and Noguer, F.R.I. and Semsarian, C. and Robyns, T. and Hofman, N. and Tanck, M.W. and Van Den Berg, M.P. and Kammeraad, J.A.E. and Krahn, A.D. and Clur, S.-A.B. and Sacher, F. and Till, J. and Skinner, J.R. and Tfelt-Hansen, J. and Probst, V. and Leenhardt, A. and Horie, M. and Swan, H. and Roberts, J.D. and Sanatani, S. and Haugaa, K.H. and Schwartz, P.J. and Ackerman, M.J. and Wilde, A.A.M.
DOI: 10.1161/CIRCEP.119.007471
2020

The merits of the ICD for inherited heart rhythm disorders: A critical re-appraisal
Trends in Cardiovascular Medicine
Roston, T.M. and Krahn, A.D. and Ong, K. and Sanatani, S.
DOI: 10.1016/j.tcm.2019.10.004
2020

Reversible cardiac dysfunction associated with physiologic high-rate dual-chamber pacing in an infant with acquired complete atrioventricular heart block
HeartRhythm Case Reports
Rathgeber, S.L. and Sanatani, G.E. and Sanatani, S.
DOI: 10.1016/j.hrcr.2019.11.001
2020

An International Multicenter Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2-Catecholaminergic Polymorphic Ventricular Tachycardia
Circulation
Ng, K. and Titus, E.W. and Lieve, K.V. and Roston, T.M. and Mazzanti, A. and Deiter, F.H. and Denjoy, I. and Ingles, J. and Till, J. and Robyns, T. and Connors, S.P. and Steinberg, C. and Abrams, D.J. and Pang, B. and Scheinman, M.M. and Bos, J.M. and Duffett, S.A. and Van Der Werf, C. and Maltret, A. and Green, M.S. and Rutberg, J. and Balaji, S. and Cadrin-Tourigny, J. and Orland, K.M. and Knight, L.M. and Brateng, C. and Wu, J. and Tang, A.S. and Skanes, A.C. and Manlucu, J. and Healey, J.S. and January, C.T. and Krahn, A.D. and Collins, K.K. and Maginot, K.R. and Fischbach, P. and Etheridge, S.P. and Eckhardt, L.L. and Hamilton, R.M. and Ackerman, M.J. and Noguer, F.R.I. and Semsarian, C. and Jura, N. and Leenhardt, A. and Gollob, M.H. and Priori, S.G. and Sanatani, S. and Wilde, A.A.M. and Deo, R.C. and Roberts, J.D.
DOI: 10.1161/CIRCULATIONAHA.120.045723
2020

The relative incidence of cardiogenic and septic shock in neonates
Paediatrics and Child Health (Canada)
Chan, K.H. and Sanatani, S. and Potts, J.E. and Harris, K.C.
DOI: 10.1093/pch/pxz078
2020

Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Mellor GJ and Panwar P and Lee AK and Steinberg C and Hathaway JA and Bartels K and Christian S and Balaji S and Roberts JD and Simpson CS and Boczek NJ and Tester DJ and Radbill AE and Laksman Z
DOI: 10.1093/europace/euz215
PubMed: 31408100
11/2019

2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy: Executive summary.
Heart rhythm
Towbin JA and McKenna WJ and Abrams DJ and Ackerman MJ and Calkins H and Darrieux FCC and Daubert JP and de Chillou C and DePasquale EC and Desai MY and Estes NAM and Hua W and Zareba W
DOI: 10.1016/j.hrthm.2019.09.019
PubMed: 31676023
11/2019

Pubertal Hormonal Changes and the Autonomic Nervous System: Potential Role in Pediatric Orthostatic Intolerance.
Frontiers in neuroscience
Coupal KE and Heeney ND and Hockin BCD and Ronsley R and Armstrong K and Sanatani S and Claydon VE
DOI: 10.3389/fnins.2019.01197
PubMed: 31798399
11/2019

Chronotropic incompetence as a risk predictor in children and young adults with catecholaminergic polymorphic ventricular tachycardia
Journal of Cardiovascular Electrophysiology
Sonia Franciosi and Thomas M. Roston and Frances K.G. Perry and Bjorn C. Knollmann and Prince J. Kannankeril and Shubhayan Sanatani
DOI: 10.1111/jce.14043
10/2019

Impact of Obesity on Left Ventricular Thickness in Children with Hypertrophic Cardiomyopathy.
Pediatric cardiology
Balaji S and DiLorenzo MP and Fish FA and Etheridge SP and Aziz PF and Russell MW and Tisma S and Pflaumer A and Sreeram N and Kubus P and Law IH and Kantoch MJ and Kertesz NJ and Shah M
DOI: 10.1007/s00246-019-02145-9
PubMed: 31263917
07/2019

Validation of finger blood pressure monitoring in children.
Blood pressure monitoring
Heeney ND and Habib F and Brar GK and Krahn G and Campbell DA and Sanatani S and Claydon VE
DOI: 10.1097/mbp.0000000000000374
PubMed: 30840608
06/2019

The challenge of implantable cardioverter-defibrillator programming and shock interpretation in treatment-refractory catecholaminergic polymorphic ventricular tachycardia.
Journal of cardiovascular medicine (Hagerstown, Md.)
Roston TM and Hart A and Krahn AD and Sanatani S
DOI: 10.2459/jcm.0000000000000814
PubMed: 31090560
05/2019

5 The Diagnostic Yield of the Exercise Stress Test in Children with Exercise-Related Symptoms.
Paediatrics & Child Health
Culjak A and Houghton K and Sanatani S and DeSouza A and Armstrong K
05/2019

2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy.
Heart rhythm
Towbin JA and McKenna WJ and Abrams DJ and Ackerman MJ and Calkins H and Darrieux FCC and Daubert JP and de Chillou C and DePasquale EC and Desai MY and Estes NAM and Hua W and Zareba W
DOI: 10.1016/j.hrthm.2019.05.007
PubMed: 31078652
05/2019

In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants
Proceedings of the National Academy of Sciences
Sanam Shafaattalab and Alison Yueh Li and Eric Lin and Charles M. Stevens and Laura J. Dewar and Francis C. Lynn and Shubhayan Sanatani and Zachary Laksman and Ryan D. Morin and Filip van Petegem and Leif Hove-Madsen and D. Peter Tieleman and Jonathan P. Davis and Glen F. Tibbits
DOI: 10.1073/pnas.1819023116
04/2019

Phospholamban cardiomyopathy: a Canadian perspective on a unique population.
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Cheung CC and Healey JS and Hamilton R and Spears D and Gollob MH and Mellor G and Steinberg C and Sanatani S and Laksman ZW and Krahn AD
DOI: 10.1007/s12471-019-1247-0
PubMed: 30806910
04/2019

Risk factors for lethal arrhythmic events in children and adolescents with hypertrophic cardiomyopathy and an implantable defibrillator: An international multicenter study.
Heart rhythm
Balaji S and DiLorenzo MP and Fish FA and Etheridge SP and Aziz PF and Russell MW and Tisma S and Pflaumer A and Sreeram N and Kubus P and Law IH and Kantoch MJ and Kertesz NJ and Shah M
DOI: 10.1016/j.hrthm.2019.04.040
PubMed: 31026510
04/2019

Cardiovascular Collapse with Intravenous Amiodarone in Children: A Multi-Center Retrospective Cohort Study.
Pediatric cardiology
Maghrabi K and Uzun O and Kirsh JA and Balaji S and Von Bergen NH and Sanatani S
DOI: 10.1007/s00246-019-02090-7
PubMed: 30929065
03/2019

Comparison of Ajmaline and Procainamide Provocation Tests in the Diagnosis of Brugada Syndrome.
JACC. Clinical electrophysiology
Cheung CC and Mellor G and Deyell MW and Ensam B and Batchvarov V and Papadakis M and Roberts JD and Leather R and Sanatani S and Healey JS and Chauhan VS and Birnie DH and Champagne J and Krahn AD
DOI: 10.1016/j.jacep.2019.01.026
PubMed: 31000106
03/2019

Beyond the exercise stress test: Does the cardiac ryanodine receptor affect intellectual function?
Heart Rhythm
Thomas M. Roston and Shubhayan Sanatani
DOI: 10.1016/j.hrthm.2018.09.003
02/2019

The challenge of implantable cardioverter-defibrillator programming and shock interpretation in treatment-refractory catecholaminergic polymorphic ventricular tachycardia
Journal of Cardiovascular Medicine
Roston, T.M. and Hart, A. and Krahn, A.D. and Sanatani, S.
DOI: 10.2459/JCM.0000000000000814
2019

Pregnancy in Catecholaminergic Polymorphic Ventricular Tachycardia
JACC: Clinical Electrophysiology
Cheung, C.C. and Lieve, K.V. and Roston, T.M. and van der Ree, M.H. and Deyell, M.W. and Andrade, J.G. and Laksman, Z.W. and Nannenberg, E.A. and Tadros, R. and Pang, B. and Rutberg, J. and Green, M.S. and Conacher, S. and Seifer, C.M. and Roberts, J.D. and Steinberg, C. and Sanatani, S. and Wilde, A.A. and Krahn, A.D.
DOI: 10.1016/j.jacep.2018.10.019
2019

Validation of finger blood pressure monitoring in children
Blood Pressure Monitoring
Heeney, N.D. and Habib, F. and Brar, G.K. and Krahn, G. and Campbell, D.A. and Sanatani, S. and Claydon, V.E.
DOI: 10.1097/MBP.0000000000000374
2019

CYP2D6 as a treatment decision aid for ER-positive non-metastatic breast cancer patients: a systematic review with accompanying clinical practice guidelines
Breast Cancer Research and Treatment
Drögemöller, B.I. and Wright, G.E.B. and Shih, J. and Monzon, J.G. and Gelmon, K.A. and Ross, C.J.D. and Amstutz, U. and Carleton, B.C. and Chang, W.C. and Connolly, M.B. and Dionne, F. and Groeneweg, G. and Loucks, C.M. and MacLeod, S.M. and Pritchard, S. and Rassekh, S.R. and Sanatani, S. and Tanoshima, R. and Virani, S.A. and Monzon, J.G. and Bhavsar, A.P. and Rieder, M.J. and Shear, N.H. and Liu, G. and Khayat, P. and Bernstein, D. and Lesko, L.J. and Aminkeng, F.
DOI: 10.1007/s10549-018-5027-0
2019

Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry.
PloS one
Roston TM and Haji-Ghassemi O and LaPage MJ and Batra AS and Bar-Cohen Y and Anderson C and Lau YR and Maginot K and Gebauer RA and Etheridge SP and Potts JE and Van Petegem F and Sanatani S
DOI: 10.1371/journal.pone.0205925
PubMed: 30403697
11/2018

Dynamic Electrocardiographic Abnormalities Captured in Timothy Syndrome.
JACC. Clinical electrophysiology
Kallas D and Franciosi S and Tester M and Roston TM and Sanatani S
DOI: 10.1016/j.jacep.2018.06.019
PubMed: 30466860
11/2018

Safety of Sports for Young Patients With Implantable Cardioverter-Defibrillators.
Circulation. Arrhythmia and electrophysiology
Saarel EV and Law I and Berul CI and Ackerman MJ and Kanter RJ and Sanatani S and Cohen MI and Berger S and Fischbach PS and Burton DA and Dziura J and Brandt C and Simone L and Li F and Lampert RJ
DOI: 10.1161/circep.118.006305
PubMed: 30520349
11/2018

Aortic Arch Homograft Reconstruction of Nonconfluent Pulmonary Arteries During Extracardiac Fontan.
World journal for pediatric & congenital heart surgery
Sughimoto K and Sanatani S and Gandhi SK
DOI: 10.1177/2150135118775383
PubMed: 30157734
09/2018

Polymorphic ventricular tachycardia associated with an episode of reflex syncope: is this the needle in the haystack?
HeartRhythm Case Reports
Matthew A. Tester and Brooke C.D. Hockin and Thuso David and Sonia Franciosi and Kevin Harris and Victoria E. Claydon and Shubhayan Sanatani
DOI: 10.1016/j.hrcr.2018.07.013
08/2018

SCN5A mutations in 442 neonates and children: genotype-phenotype correlation and identification of higher-risk subgroups.
European heart journal
Baruteau AE and Kyndt F and Behr ER and Vink AS and Lachaud M and Joong A and Schott JJ and Horie M and Denjoy I and Crotti L and Shimizu W and Bos JM and Stephenson EA and Wong L and Probst V
DOI: 10.1093/eurheartj/ehy412
PubMed: 30059973
08/2018

Early Repolarization Pattern Inheritance in the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER).
JACC. Clinical electrophysiology
Malhi N and So PP and Cheung CC and Laksman ZWM and Healey JS and Chauhan VS and Green MS and Champagne J and Steinberg C and Sanatani S and Angaran P and Duff H and Roberts JD and Krahn AD
DOI: 10.1016/j.jacep.2018.07.001
PubMed: 30466855
08/2018

Implantable cardioverter-defibrillator use in catecholaminergic polymorphic ventricular tachycardia: A systematic review.
Heart rhythm
Roston TM and Jones K and Hawkins NM and Bos JM and Schwartz PJ and Perry F and Ackerman MJ and Laksman ZWM and Kaul P and Lieve KVV and Atallah J and Krahn AD and Sanatani S
DOI: 10.1016/j.hrthm.2018.06.046
PubMed: 30063211
07/2018

Predictors of ECG Screening Failure for the Subcutaneous Implantable Cardioverter Defibrillator in Children. A Prospective Multi-Center Study.
Heart rhythm
Campbell M and Moore JP and Sreeram N and von Alvensleben JC and Shah A and Batra A and Law I and Sanatani S and Thomas V and Nik-Ahd F and Williams S and Nosavan N and Maldonado J and Balaji S
DOI: 10.1016/j.hrthm.2018.01.004
PubMed: 29309839
01/2018

A Population-Based Study of Syncope in the Young
Canadian Journal of Cardiology
Roston, T.M. and Tran, D.T. and Sanatani, S. and Sandhu, R. and Sheldon, R. and Kaul, P.
DOI: 10.1016/j.cjca.2017.12.006
2018

Functional characterization of a novel hERG variant in a family with recurrent sudden infant death syndrome: Retracting a genetic diagnosis
Forensic Science International
Sergeev, V. and Perry, F. and Roston, T.M. and Sanatani, S. and Tibbits, G.F. and Claydon, T.W.
DOI: 10.1016/j.forsciint.2017.12.028
2018

The accessibility and utilization of genetic testing for inherited heart rhythm disorders: a Canadian cross-sectional survey study
Journal of Community Genetics
Roston, T.M. and Dewar, L. and Franciosi, S. and Hathaway, J. and Bartels, K. and Cunningham, T. and Gibbs, K.A. and Sheps, S. and Laksman, Z.W.M. and Sanatani, S. and Krahn, A.D.
DOI: 10.1007/s12687-017-0348-y
2018

Life-Threatening Event Risk in Children With Wolff-Parkinson-White Syndrome: A Multicenter International Study
JACC: Clinical Electrophysiology
Etheridge, S.P. and Escudero, C.A. and Blaufox, A.D. and Law, I.H. and Dechert-Crooks, B.E. and Stephenson, E.A. and Dubin, A.M. and Ceresnak, S.R. and Motonaga, K.S. and Skinner, J.R. and Marcondes, L.D. and Perry, J.C. and Collins, K.K. and Seslar, S.P. and Cabrera, M. and Uzun, O. and Cannon, B.C. and Aziz, P.F. and Kubu?, P. and Tanel, R.E. and Valdes, S.O. and Sami, S. and Kertesz, N.J. and Maldonado, J. and Erickson, C. and Moore, J.P. and Asakai, H. and Mill, L. and Abcede, M. and Spector, Z.Z. and Menon, S. and Shwayder, M. and Bradley, D.J. and Cohen, M.I. and Sanatani, S.
DOI: 10.1016/j.jacep.2017.10.009
2018

Safety of Sports for Young Patients With Implantable Cardioverter-Defibrillators
Circulation. Arrhythmia and electrophysiology
Saarel, E.V. and Law, I. and Berul, C.I. and Ackerman, M.J. and Kanter, R.J. and Sanatani, S. and Cohen, M.I. and Berger, S. and Fischbach, P.S. and Burton, D.A. and Dziura, J. and Brandt, C. and Simone, L. and Li, F. and Olshansky, B. and Cannom, D.S. and Lampert, R.J.
DOI: 10.1161/CIRCEP.118.006305
2018

The clinical and genetic spectrum of catecholaminergic polymorphic ventricular tachycardia: Findings from an international multicentre registry
Europace
Roston, T.M. and Yuchi, Z. and Kannankeril, P.J. and Hathaway, J. and Vinocur, J.M. and Etheridge, S.P. and Potts, J.E. and Maginot, K.R. and Salerno, J.C. and Cohen, M.I. and Hamilton, R.M. and Pflaumer, A. and Mohammed, S. and Kimlicka, L. and Kanter, R.J. and Lapage, M.J. and Collins, K.K. and Gebauer, R.A. and Temple, J.D. and Batra, A.S. and Erickson, C. and Miszczak-Knecht, M. and Kubu?, P. and Bar-Cohen, Y. and Kantoch, M. and Thomas, V.C. and Hessling, G. and Anderson, C. and Young, M.-L. and Choi, S.H.J. and Cabrera Ortega, M. and Lau, Y.R. and Johnsrude, C.L. and Fournier, A. and Van Petegem, F. and Sanatani, S.
DOI: 10.1093/europace/euw389
2018

The Safety and Effectiveness of Flecainide in Children in the Current Era.
Pediatric cardiology
Cunningham T and Uzun O and Morris R and Franciosi S and Wong A and Jeremiasen I and Sherwin E and Sanatani S
DOI: 10.1007/s00246-017-1707-5
PubMed: 28840327
12/2017

Response Letter to 'Optimising physiology for adolescents with dysautonomia'.
Acta paediatrica (Oslo, Norway : 1992)
Armstrong KR and De Souza AM and Sneddon PL and Potts JE and Claydon VE and Sanatani S
DOI: 10.1111/apa.14058
PubMed: 28906019
12/2017

The 2017 Seventh World Congress of Pediatric Cardiology & Cardiac Surgery: Week in review: electrophysiology.
Cardiology in the young
Cohen MI and Etheridge S and Sanatani S and Celiker A
DOI: 10.1017/s1047951117002268
PubMed: 29286280
12/2017

Differential calcium sensitivity in NaV 1.5 mixed syndrome mutants.
The Journal of physiology
Abdelsayed M and Baruteau AE and Gibbs K and Sanatani S and Krahn AD and Probst V and Ruben PC
DOI: 10.1113/jp274536
PubMed: 28734073
09/2017

Investigating the Genetic Causes of Sudden Unexpected Death in Children Through Targeted Next-Generation Sequencing Analysis.
Circulation. Cardiovascular genetics
Dewar LJ and Alcaide M and Fornika D and D'Amato L and Shafaatalab S and Stevens CM and Balachandra T and Phillips SM and Sanatani S and Morin RD and Tibbits GF
DOI: 10.1161/circgenetics.116.001738
PubMed: 28807990
08/2017

Loss-of-Function KCNE2 Variants: True Monogenic Culprits of Long-QT Syndrome or Proarrhythmic Variants Requiring Secondary Provocation?
Circulation. Arrhythmia and electrophysiology
Roberts JD and Krahn AD and Ackerman MJ and Rohatgi RK and Moss AJ and Nazer B and Tadros R and Gerull B and Sanatani S and Wijeyeratne YD and Baruteau AE and Muir AR and Pang B and Scheinman MM
DOI: 10.1161/circep.117.005282
PubMed: 28794082
08/2017

The role of the autonomic nervous system in arrhythmias and sudden cardiac death.
Autonomic neuroscience : basic & clinical
Franciosi S and Perry FKG and Roston TM and Armstrong KR and Claydon VE and Sanatani S
DOI: 10.1016/j.autneu.2017.03.005
PubMed: 28392310
07/2017

KCNQ1 p.L353L affects splicing and modifies the phenotype in a founder population with long QT syndrome type 1.
Journal of medical genetics
Kapplinger JD and Erickson A and Asuri S and Tester DJ and McIntosh S and Kerr CR and Morrison J and Tang A and Sanatani S and Arbour L and Ackerman MJ
DOI: 10.1136/jmedgenet-2016-104153
PubMed: 28264985
06/2017

Genetic Testing in the Evaluation of Unexplained Cardiac Arrest: From the CASPER (Cardiac Arrest Survivors With Preserved Ejection Fraction Registry).
Circulation. Cardiovascular genetics
DOI: 10.1161/circgenetics.116.001686
PubMed: 28600387
06/2017

Exercise and the multidisciplinary holistic approach to adolescent dysautonomia.
Acta Paediatrica (Oslo, Norway : 1992)
Armstrong KR and De Souza AM and Sneddon PL and Potts JE and Claydon VE and Sanatani S
DOI: 10.1111/apa.13750
PubMed: 28112424
04/2017

The Current State and Future Potential of Pediatric and Congenital Electrophysiology.
JACC. Clinical electrophysiology
Sanatani S and Cunningham T and Khairy P and Cohen MI and Hamilton RM and Ackerman MJ
DOI: 10.1016/j.jacep.2017.01.008
PubMed: 29759513
03/2017

Pharmacogenomic screening for anthracycline-induced cardiotoxicity in childhood cancer.
British journal of clinical pharmacology
Aminkeng F and Ross CJD and Rassekh SR and Rieder MJ and Bhavsar AP and Sanatani S and Bernstein D and Hayden MR and Amstutz U and Carleton BC
DOI: 10.1111/bcp.13218
PubMed: 28317142
03/2017

Canadian Cardiovascular Society and Canadian Pediatric Cardiology Association Position Statement on the Approach to Syncope in the Pediatric Patient.
The Canadian Journal of Cardiology
Sanatani S and Chau V and Fournier A and Dixon A and Blondin R and Sheldon RS
DOI: 10.1016/j.cjca.2016.09.006
PubMed: 27838109
02/2017

Suppression-of-function mutations in the cardiac ryanodine receptor: Emerging evidence for a novel arrhythmia syndrome?
Heart rhythm
Roston TM and Sanatani S and Chen SR
DOI: 10.1016/j.hrthm.2016.11.004
PubMed: 27818320
01/2017

Catecholaminergic polymorphic ventricular tachycardia: a model for genotype-specific therapy.
Current opinion in cardiology
Roston TM and Van Petegem F and Sanatani S
DOI: 10.1097/hco.0000000000000360
PubMed: 27861184
01/2017

Advances in the diagnosis and treatment of catecholaminergic polymorphic ventricular tachycardia.
Cardiology in the young
Roston TM and Cunningham TC and Sanatani S
DOI: 10.1017/s1047951116002237
PubMed: 28084961
01/2017

Morbidities in the ultra-athlete and marathoner.
Cardiology in the young
Cunningham TC and Maghrabi K and Sanatani S
DOI: 10.1017/s1047951116002304
PubMed: 28084966
01/2017

Genetic Insurance Discrimination in Sudden Arrhythmia Death Syndromes: Empirical Evidence From a Cross-Sectional Survey in North America.
Circulation. Cardiovascular genetics
Mohammed S and Lim Z and Dean PH and Potts JE and Tang JN and Etheridge SP and Lara A and Husband P and Sherwin ED and Ackerman MJ and Sanatani S
DOI: 10.1161/circgenetics.116.001442
PubMed: 28119333
01/2017

Novel Variant in the ANK2 Membrane-Binding Domain Is Associated With Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population With a High Rate of Long QT Syndrome.
Circulation. Cardiovascular genetics
Swayne LA and Murphy NP and Asuri S and Chen L and Xu X and McIntosh S and Wang C and Lancione PJ and Roberts JD and Kerr C and Sanatani S and Sherwin E and Kline CF and Zhang M and Mohler PJ and Arbour LT
DOI: 10.1161/circgenetics.116.001537
PubMed: 28196901
01/2017

Beyond the Electrocardiogram: Mutations in Cardiac Ion Channel Genes Underlie Nonarrhythmic Phenotypes.
Clinical Medicine Insights. Cardiology
Roston TM and Cunningham T and Lehman A and Laksman ZW and Krahn AD and Sanatani S
DOI: 10.1177/1179546817698134
PubMed: 28469493
2017

Catecholaminergic polymorphic ventricular tachycardia: A model for genotype-specific therapy
Current Opinion in Cardiology
Roston, T.M. and Van Petegem, F. and Sanatani, S.
DOI: 10.1097/HCO.0000000000000360
2017

Investigating the Genetic Causes of Sudden Unexpected Death in Children Through Targeted Next-Generation Sequencing Analysis
Circulation: Cardiovascular Genetics
Dewar, L.J. and Alcaide, M. and Fornika, D. and D'Amato, L. and Shafaatalab, S. and Stevens, C.M. and Balachandra, T. and Phillips, S.M. and Sanatani, S. and Morin, R.D. and Tibbits, G.F.
DOI: 10.1161/CIRCGENETICS.116.001738
2017

Advances in the diagnosis and treatment of catecholaminergic polymorphic ventricular tachycardia
Cardiology in the Young
Roston, T.M. and Cunningham, T.C. and Sanatani, S.
DOI: 10.1017/S1047951116002237
2017

Differential calcium sensitivity in NaV1.5 mixed syndrome mutants
Journal of Physiology
Abdelsayed, M. and Baruteau, A.-E. and Gibbs, K. and Sanatani, S. and Krahn, A.D. and Probst, V. and Ruben, P.C.
DOI: 10.1113/JP274536
2017

Genetic Insurance Discrimination in Sudden Arrhythmia Death Syndromes Empirical Evidence from a Cross-Sectional Survey in North America
Circulation: Cardiovascular Genetics
Mohammed, S. and Lim, Z. and Dean, P.H. and Potts, J.E. and Tang, J.N.C. and Etheridge, S.P. and Lara, A. and Husband, P. and Sherwin, E.D. and Ackerman, M.J. and Sanatani, S.
DOI: 10.1161/CIRCGENETICS.116.001442
2017

Genetic Testing in the Evaluation of Unexplained Cardiac Arrest: From the CASPER (Cardiac Arrest Survivors with Preserved Ejection Fraction Registry)
Circulation: Cardiovascular Genetics
Mellor, G. and Laksman, Z.W.M. and Tadros, R. and Roberts, J.D. and Gerull, B. and Simpson, C.S. and Klein, G.J. and Champagne, J. and Talajic, M. and Gardner, M. and Steinberg, C. and Arbour, L. and Birnie, D.H. and Angaran, P. and Leather, R. and Sanatani, S. and Chauhan, V.S. and Seifer, C. and Healey, J.S. and Krahn, A.D.
DOI: 10.1161/CIRCGENETICS.116.001686
2017

Novel Variant in the ANK2 Membrane-Binding Domain Is Associated with Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population with a High Rate of Long QT Syndrome
Circulation: Cardiovascular Genetics
Swayne, L.A. and Murphy, N.P. and Asuri, S. and Chen, L. and Xu, X. and McIntosh, S. and Wang, C. and Lancione, P.J. and Roberts, J.D. and Kerr, C. and Sanatani, S. and Sherwin, E. and Kline, C.F. and Zhang, M. and Mohler, P.J. and Arbour, L.T.
DOI: 10.1161/CIRCGENETICS.116.001537
2017

Morbidities in the ultra-athlete and marathoner
Cardiology in the Young
Cunningham, T.C. and Maghrabi, K. and Sanatani, S.
DOI: 10.1017/S1047951116002304
2017

Loss-of-Function KCNE2 Variants: True Monogenic Culprits of Long-QT Syndrome or Proarrhythmic Variants Requiring Secondary Provocation?
Circulation: Arrhythmia and Electrophysiology
Roberts, J.D. and Krahn, A.D. and Ackerman, M.J. and Rohatgi, R.K. and Moss, A.J. and Nazer, B. and Tadros, R. and Gerull, B. and Sanatani, S. and Wijeyeratne, Y.D. and Baruteau, A.-E. and Muir, A.R. and Pang, B. and Cadrin-Tourigny, J. and Talajic, M. and Rivard, L. and Tester, D.J. and Liu, T. and Whitman, I.R. and Wojciak, J. and Conacher, S. and Gula, L.J. and Leong-Sit, P. and Manlucu, J. and Green, M.S. and Hamilton, R. and Healey, J.S. and Lopes, C.M. and Behr, E.R. and Wilde, A.A. and Gollob, M.H. and Scheinman, M.M.
DOI: 10.1161/CIRCEP.117.005282
2017

Cost Analysis of Patients Referred for Inherited Heart Rhythm Disorder Evaluation
Canadian Journal of Cardiology
Janzen, M.L. and Cheung, C. and Sanatani, S. and Cunningham, T. and Kerr, C. and Steinberg, C. and Sherwin, E. and Arbour, L. and Deyell, M.W. and Andrade, J.G. and Lehman, A.M. and Gula, L.J. and Krahn, A.D.
DOI: 10.1016/j.cjca.2016.12.009
2017

The 2017 Seventh World Congress of Pediatric Cardiology & Cardiac Surgery: Week in review: Electrophysiology
Cardiology in the Young
Cohen, M.I. and Etheridge, S. and Sanatani, S. and Celiker, A.
DOI: 10.1017/S1047951117002268
2017

A novel RYR2 loss-of-function mutation (I4855M) is associated with left ventricular non-compaction and atypical catecholaminergic polymorphic ventricular tachycardia
Journal of Electrocardiology
Roston, T.M. and Guo, W. and Krahn, A.D. and Wang, R. and Van Petegem, F. and Sanatani, S. and Chen, S.R.W. and Lehman, A.
DOI: 10.1016/j.jelectrocard.2016.09.006
2017

Ischemia-reperfusion destabilizes rhythmicity in immature atrioventricular pacemakers: A predisposing factor for postoperative arrhythmias in neonate rabbits.
Heart rhythm
Chenliu C and Sheng X and Dan P and Qu Y and Claydon VE and Lin E and Hove-Madsen L and Sanatani S and Tibbits GF
DOI: 10.1016/j.hrthm.2016.07.022
PubMed: 27451283
12/2016

The Canadian Arrhythmogenic Right Ventricular Cardiomyopathy Registry: Rationale, Design, and Preliminary Recruitment.
The Canadian Journal of Cardiology
Krahn AD and Healey JS and Gerull B and Angaran P and Chakrabarti S and Sanatani S and Arbour L and Laksman ZW and Carroll SL and Seifer C and Green M and Roberts JD and Talajic M and Gardner M
DOI: 10.1016/j.cjca.2016.04.004
PubMed: 27474350
12/2016

Management of Gene-Positive Catecholaminergic Polymorphic Ventricular Tachycardia: Are the Long Term Outcomes on Therapy Really So Poor?
Circulation journal : official journal of the Japanese Circulation Society
Roston TM and Sanatani S
DOI: 10.1253/circj.cj-16-0842
PubMed: 27840378
11/2016

A Clinical Risk Score to Improve the Diagnosis of Tachycardia-Induced Cardiomyopathy in Childhood.
The American journal of cardiology
Moore JP and Wang S and Albers EL and Salerno JC and Stephenson EA and Shah MJ and Pflaumer A and Czosek RJ and Garnreiter JM and Collins K and Papez AL and Sanatani S and Cain NB and Shannon KM
DOI: 10.1016/j.amjcard.2016.07.008
PubMed: 27515893
10/2016

Use of dofetilide in adult patients with atrial arrhythmias and congenital heart disease: A PACES collaborative study.
Heart rhythm
El-Assaad I and Al-Kindi SG and Abraham J and Sanatani S and Bradley DJ and Halsey C and Law IH and Balaji S and Shetty I and Aziz PF
DOI: 10.1016/j.hrthm.2016.07.016
PubMed: 27435587
10/2016

Cardiac Abnormalities in First-Degree Relatives of Unexplained Cardiac Arrest Victims: A Report From the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry.
Circulation. Arrhythmia and electrophysiology
Steinberg C and Padfield GJ and Champagne J and Sanatani S and Angaran P and Andrade JG and Roberts JD and Healey JS and Chauhan VS and Birnie DH and Janzen M and Gerull B and Klein GJ and Krahn AD
DOI: 10.1161/circep.115.004274
PubMed: 27635072
09/2016

Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity.
British journal of clinical pharmacology
Aminkeng F and Ross CJ and Rassekh SR and Hwang S and Rieder MJ and Bhavsar AP and Smith A and Sanatani S and Gelmon KA and Bernstein D and Hayden MR and Amstutz U and Carleton BC and CPNDS Clinical Practice Recommendations Group
DOI: 10.1111/bcp.13008
PubMed: 27197003
09/2016

Pediatric & Congenital Electrophysiology Society: building an international paediatric electrophysiology organisation.
Cardiology in the young
Cohen M and Sanatani S and Stephenson E and Skinner J and Drago F and Davis A and Janousek J and Rosenthal E and Collins KK and Triedman J
DOI: 10.1017/s1047951115002553
PubMed: 27075202
08/2016

Congenital heart disease confounding the diagnosis of arrhythmogenic right ventricular cardiomyopathy.
HeartRhythm case reports
Kiamanesh O and Farhan M and Sanatani S and Grosse-Wortmann L and Duncan W and Hamilton RM
DOI: 10.1016/j.hrcr.2016.01.007
PubMed: 28491693
07/2016

Catecholaminergic Polymorphic Ventricular Tachycardia: Activity as Tolerated?
JACC. Clinical electrophysiology
Krahn AD and Sanatani S
DOI: 10.1016/j.jacep.2016.04.002
PubMed: 29766882
06/2016

Pediatric & Congenital Electrophysiology Society: building an international paediatric electrophysiology organisation.
Heart rhythm
Cohen M and Sanatani S and Stephenson E and Skinner J and Drago F and Davis A and Janousek J and Rosenthal E and Collins KK and Triedman J
DOI: 10.1016/j.hrthm.2016.01.013
PubMed: 27090729
05/2016

Response to Letter Regarding Article, "Outcome of Apparently Unexplained Cardiac Arrest: Results From Investigation and Follow-Up of the Prospective Cardiac Arrest Survivors With Preserved Ejection Fraction Registry".
Circulation. Arrhythmia and electrophysiology
Herman AR and Cheung C and Gerull B and Simpson CS and Birnie DH and Klein GJ and Champagne J and Healey JS and Gibbs K and Talajic M and Gardner M and Bennett MT and Steinberg C and Krahn AD
DOI: 10.1161/circep.116.004012
PubMed: 27069091
04/2016

Exercise and Inherited Arrhythmias.
The Canadian journal of cardiology
Cheung CC and Laksman ZW and Mellor G and Sanatani S and Krahn AD
DOI: 10.1016/j.cjca.2016.01.007
PubMed: 26927864
04/2016

Evaluation and management of bradycardia in neonates and children.
European journal of pediatrics
Baruteau AE and Perry JC and Sanatani S and Horie M and Dubin AM
DOI: 10.1007/s00431-015-2689-z
PubMed: 26780751
02/2016

Flecainide monotherapy is an option for selected patients with catecholaminergic polymorphic ventricular tachycardia intolerant of ß-blockade.
Heart rhythm
Padfield GJ and AlAhmari L and Lieve KV and AlAhmari T and Roston TM and Wilde AA and Krahn AD and Sanatani S
DOI: 10.1016/j.hrthm.2015.09.027
PubMed: 26416620
02/2016

Characterization of Myocardial Repolarization Reserve in Adolescent Females With Anorexia Nervosa.
Circulation
Padfield GJ and Escudero CA and DeSouza AM and Steinberg C and Gibbs K and Puyat JH and Lam PY and Sanatani S and Sherwin E and Potts JE and Sandor G and Krahn AD
DOI: 10.1161/circulationaha.115.016697
PubMed: 26769740
02/2016

Outcome of Apparently Unexplained Cardiac Arrest: Results From Investigation and Follow-Up of the Prospective Cardiac Arrest Survivors With Preserved Ejection Fraction Registry.
Circulation. Arrhythmia and electrophysiology
Herman AR and Cheung C and Gerull B and Simpson CS and Birnie DH and Klein GJ and Champagne J and Healey JS and Gibbs K and Talajic M and Gardner M and Bennett MT and Steinberg C and Krahn AD
DOI: 10.1161/circep.115.003619
PubMed: 26783233
01/2016

Characterization of Myocardial Repolarization Reserve in Adolescent Females with Anorexia Nervosa
Circulation
Padfield, G.J. and Escudero, C.A. and Desouza, A.M. and Steinberg, C. and Gibbs, K. and Puyat, J.H. and Lam, P.Y. and Sanatani, S. and Sherwin, E. and Potts, J.E. and Sandor, G. and Krahn, A.D.
DOI: 10.1161/CIRCULATIONAHA.115.016697
2016

Pediatric & Congenital Electrophysiology Society: Building an international paediatric electrophysiology organisation
Cardiology in the Young
Cohen, M. and Sanatani, S. and Stephenson, E. and Skinner, J. and Drago, F. and Davis, A. and Janousek, J. and Rosenthal, E. and Collins, K.K. and Triedman, J.
DOI: 10.1017/S1047951115002553
2016

Response to Letter Regarding Article, "Outcome of apparently unexplained cardiac arrest: Results from investigation and follow-up of the prospective cardiac arrest survivors with preserved ejection fraction registry"
Circulation: Arrhythmia and Electrophysiology
Herman, A.R.M. and Cheung, C. and Gerull, B. and Simpson, C.S. and Birnie, D.H. and Klein, G.J. and Champagne, J. and Healey, J.S. and Gibbs, K. and Talajic, M. and Gardner, M. and Bennett, M.T. and Steinberg, C. and Janzen, M. and Gollob, M.H. and Angaran, P. and Yee, R. and Leather, R. and Chakrabarti, S. and Sanatani, S. and Chauhan, V.S. and Krahn, A.D.
DOI: 10.1161/CIRCEP.116.004012
2016

Management of gene-positive catecholaminergic polymorphic ventricular tachycardia: Are the long term outcomes on therapy really so poor?
Circulation Journal
Roston, T.M. and Sanatani, S.
DOI: 10.1253/circj.CJ-16-0842
2016

Outcome of apparently unexplained cardiac arrest: Results from investigation and follow-up of the prospective cardiac arrest survivors with preserved ejection fraction registry
Circulation: Arrhythmia and Electrophysiology
Herman, A.R.M. and Cheung, C. and Gerull, B. and Simpson, C.S. and Birnie, D.H. and Klein, G.J. and Champagne, J. and Healey, J.S. and Gibbs, K. and Talajic, M. and Gardner, M. and Bennett, M.T. and Steinberg, C. and Janzen, M. and Gollob, M.H. and Angaran, P. and Yee, R. and Leather, R. and Chakrabarti, S. and Sanatani, S. and Chauhan, V.S. and Krahn, A.D.
DOI: 10.1161/CIRCEP.115.003619
2016

Cardiac Abnormalities in First-Degree Relatives of Unexplained Cardiac Arrest Victims
Circulation: Arrhythmia and Electrophysiology
Steinberg, C. and Padfield, G.J. and Champagne, J. and Sanatani, S. and Angaran, P. and Andrade, J.G. and Roberts, J.D. and Healey, J.S. and Chauhan, V.S. and Birnie, D.H. and Janzen, M. and Gerull, B. and Klein, G.J. and Leather, R. and Simpson, C.S. and Seifer, C. and Talajic, M. and Gardner, M. and Krahn, A.D.
DOI: 10.1161/CIRCEP.115.004274
2016

Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: a retrospective study.
Paediatric anaesthesia
Görges M and Whyte SD and Sanatani S and Dawes J and Montgomery CJ and Ansermino JM
DOI: 10.1111/pan.12780
PubMed: 26507917
12/2015

Choking-induced cardiac arrest unmasks a diagnosis of catecholaminergic polymorphic ventricular tachycardia.
HeartRhythm case reports
Roston TM and AlAhmari L and Krahn AD and Sherwin E and Sanatani S
DOI: 10.1016/j.hrcr.2015.08.007
PubMed: 28491614
11/2015

Catecholaminergic polymorphic ventricular tachycardia in children: analysis of therapeutic strategies and outcomes from an international multicenter registry.
Circulation. Arrhythmia and electrophysiology
Roston TM and Vinocur JM and Maginot KR and Mohammed S and Salerno JC and Etheridge SP and Cohen M and Hamilton RM and Pflaumer A and Kanter RJ and Potts JE and LaPage MJ and Sanatani S
DOI: 10.1161/circep.114.002217
PubMed: 25713214
06/2015

Catecholaminergic Polymorphic Ventricular Tachycardia in Children: Analysis of Therapeutic Strategies and Outcomes from an International Multicenter Registry
Circulation: Arrhythmia and Electrophysiology
Roston, T.M. and Vinocur, J.M. and Maginot, K.R. and Mohammed, S. and Salerno, J.C. and Etheridge, S.P. and Cohen, M. and Hamilton, R.M. and Pflaumer, A. and Kanter, R.J. and Potts, J.E. and LaPage, M.J. and Collins, K.K. and Gebauer, R.A. and Temple, J.D. and Batra, A.S. and Erickson, C. and Miszczak-Knecht, M. and Kubu?, P. and Bar-Cohen, Y. and Kantoch, M. and Thomas, V.C. and Hessling, G. and Anderson, C. and Young, M.-L. and Ortega, M.C. and Lau, Y.R. and Johnsrude, C.L. and Fournier, A. and Kannankeril, P.J. and Sanatani, S.
DOI: 10.1161/CIRCEP.114.002217
2015

Paediatric patient family engagement with clinical research at a tertiary care paediatric hospital.
Paediatrics & Child Health
Gill C and Ansermino MJ and Sanatani S and Mulpuri K and Doan Q
PubMed: 25587233
12/2014

Should early extubation be the goal for children after congenital cardiac surgery?
The Journal of thoracic and cardiovascular surgery
Harris KC and Holowachuk S and Pitfield S and Sanatani S and Froese N and Potts JE and Gandhi SK
DOI: 10.1016/j.jtcvs.2014.06.093
PubMed: 25156467
12/2014

Evaluation of genes encoding for the transient outward current (Ito) identifies the KCND2 gene as a cause of J-wave syndrome associated with sudden cardiac death.
Circulation. Cardiovascular genetics
Perrin MJ and Adler A and Green S and Al-Zoughool F and Doroshenko P and Orr N and Uppal S and Healey JS and Birnie D and Sanatani S and Gardner M and Champagne J and Simpson C and Gollob MH
DOI: 10.1161/circgenetics.114.000623
PubMed: 25214526
12/2014

The safety of modern anesthesia for children with long QT syndrome.
Anesthesia and analgesia
Whyte SD and Nathan A and Myers D and Watkins SC and Kannankeril PJ and Etheridge SP and Andrade J and Collins KK and Law IH and Hayes J and Sanatani S
DOI: 10.1213/ane.0000000000000389
PubMed: 25076102
10/2014

Current management of focal atrial tachycardia in children: a multicenter experience.
Circulation. Arrhythmia and electrophysiology
Kang KT and Etheridge SP and Kantoch MJ and Tisma-Dupanovic S and Bradley DJ and Balaji S and Hamilton RM and Singh AK and Cannon BC and Schaffer MS and Potts JE and Sanatani S
DOI: 10.1161/circep.113.001423
PubMed: 25015944
08/2014

An international multicenter study comparing arrhythmia prevalence between the intracardiac lateral tunnel and the extracardiac conduit type of Fontan operations.
The Journal of thoracic and cardiovascular surgery
Balaji S and Daga A and Bradley DJ and Etheridge SP and Law IH and Batra AS and Sanatani S and Singh AK and Gajewski KK and Tsao S and Singh HR and Tisma-Dupanovic S and Tateno S and Shah M
DOI: 10.1016/j.jtcvs.2013.08.070
PubMed: 24172692
08/2014

Permanent junctional reciprocating tachycardia in children: a multicenter experience.
Heart rhythm
Kang KT and Potts JE and Radbill AE and La Page MJ and Papagiannis J and Garnreiter JM and Kubus P and Kantoch MJ and Von Bergen NH and Fournier A and Côté JM and Paul T and Sanatani S
DOI: 10.1016/j.hrthm.2014.04.033
PubMed: 24769425
08/2014

Nonuniform and variable arrangements of ryanodine receptors within mammalian ventricular couplons.
Circulation research
Asghari P and Scriven DR and Sanatani S and Gandhi SK and Campbell AI and Moore ED
DOI: 10.1161/circresaha.115.303897
PubMed: 24786399
07/2014

Predictors of myocardial recovery in pediatric tachycardia-induced cardiomyopathy.
Heart rhythm
Moore JP and Patel PA and Shannon KM and Albers EL and Salerno JC and Stein MA and Stephenson EA and Mohan S and Shah MJ and Asakai H and Pflaumer A and Czosek RJ and Everitt MD and Balaji S
DOI: 10.1016/j.hrthm.2014.04.023
PubMed: 24751393
07/2014

Procainamide infusion in the evaluation of unexplained cardiac arrest: from the Cardiac Arrest Survivors with Preserved Ejection Fraction Registry (CASPER).
Heart rhythm
Somani R and Krahn AD and Healey JS and Chauhan VS and Birnie DH and Champagne J and Sanatani S and Angaran P and Gow RM and Chakrabarti S and Gerull B and Yee R and Skanes AC and Gula LJ and Simpson CS
DOI: 10.1016/j.hrthm.2014.03.022
PubMed: 24657429
06/2014

Electrocardiogram interpretation by Canadian general paediatricians: Examining practice, accuracy and confidence.
Paediatrics & Child Health
Escudero CA and Sanatani S and Wong KK and Templeton CG
DOI: 10.1093/pch/19.2.77
PubMed: 24596480
02/2014

Reply to letter from Nair et al.--anatomical considerations for cardiac resynchronization therapy in transposition of the great arteries.
The Canadian journal of cardiology
Escudero C and Khairy P and Sanatani S
DOI: 10.1016/j.cjca.2013.09.027
PubMed: 24290863
02/2014

Evolution of clinical diagnosis in patients presenting with unexplained cardiac arrest or syncope due to polymorphic ventricular tachycardia.
Heart rhythm
Vittoria Matassini M and Krahn AD and Gardner M and Champagne J and Sanatani S and Birnie DH and Gollob MH and Chauhan V and Simpson CS and Hamilton RM and Talajic M and Ahmad K and Healey JS
DOI: 10.1016/j.hrthm.2013.11.008
PubMed: 24239842
02/2014

Supraventricular tachycardias
Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care
Escudero, C. and Blom, N.A. and Sanatani, S.
DOI: 10.1007/978-1-4471-4619-3_137
2014

Current management of focal atrial tachycardia in children a multicenter experience
Circulation: Arrhythmia and Electrophysiology
Kang, K.T. and Etheridge, S.P. and Kantoch, M.J. and Tisma-Dupanovic, S. and Bradley, D.J. and Balaji, S. and Hamilton, R.M. and Singh, A.K. and Cannon, B.C. and Schaffer, M.S. and Potts, J.E. and Sanatani, S.
DOI: 10.1161/CIRCEP.113.001423
2014

Evaluation of genes encoding for the transient outward current (Ito) identifies the KCND2 gene as a cause of J-wave syndrome associated with sudden cardiac death
Circulation: Cardiovascular Genetics
Perrin, M.J. and Adler, A. and Green, S. and Al-Zoughool, F. and Doroshenko, P. and Orr, N. and Uppal, S. and Healey, J.S. and Birnie, D. and Sanatani, S. and Gardner, M. and Champagne, J. and Simpson, C. and Ahmad, K. and Van Den Berg, M.P. and Chauhan, V. and Backx, P.H. and Van Tintelen, J.P. and Krahn, A.D. and Gollob, M.H.
DOI: 10.1161/CIRCGENETICS.114.000623
2014

Nonuniform and variable arrangements of ryanodine receptors within mammalian ventricular couplons
Circulation Research
Asghari, P. and Scriven, D.R.L. and Sanatani, S. and Gandhi, S.K. and Campbell, A.I.M. and Moore, E.D.W.
DOI: 10.1161/CIRCRESAHA.115.303897
2014

The safety of modern anesthesia for children with long QT syndrome
Anesthesia and Analgesia
Whyte, S.D. and Nathan, A. and Myers, D. and Watkins, S.C. and Kannankeril, P.J. and Etheridge, S.P. and Andrade, J. and Collins, K.K. and Law, I.H. and Hayes, J. and Sanatani, S.
DOI: 10.1213/ANE.0000000000000389
2014

Postmortem genetic diagnosis of long QT syndrome in a case of sudden unexplained death of a young child: A case report and overview of regional guidelines for genetic testing
British Columbia Medical Journal
Lee, A.F. and Krahn, A.D. and Sanatani, S. and McFadden, D.E.
2014

Paediatric patient family engagement with clinical research at a tertiary care paediatric hospital
Paediatrics and Child Health (Canada)
Gill, C. and Ansermino, M.J. and Sanatani, S. and Mulpuri, K. and Doan, Q.
2014

TMEM43 mutations associated with arrhythmogenic right ventricular cardiomyopathy in non-Newfoundland populations.
Human genetics
Baskin B and Skinner JR and Sanatani S and Terespolsky D and Krahn AD and Ray PN and Scherer SW and Hamilton RM
DOI: 10.1007/s00439-013-1323-2
PubMed: 23812740
11/2013

Charting a course for cardiac electrophysiology training in Canada: the vital role of fellows in advanced cardiovascular care.
The Canadian journal of cardiology
Leather RA and Gardner M and Green MS and Kavanagh K and Macle L and Ahmad K and Gray C and Ayala-Paredes F and Guerra PG and O'Hara G and Essebag V and Sturmer M and Baranchuk A and Krahn AD
DOI: 10.1016/j.cjca.2013.08.019
PubMed: 24182759
11/2013

Lone atrial fibrillation in the pediatric population.
The Canadian Journal of Cardiology
Mills LC and Gow RM and Myers K and Kantoch MJ and Gross GJ and Fournier A and Sanatani S
DOI: 10.1016/j.cjca.2013.06.014
PubMed: 24074972
10/2013

Physical activity recommendations for patients with electrophysiologic and structural congenital heart disease: a survey of Canadian health care providers.
Pediatric cardiology
Roston TM and De Souza AM and Sandor GG and Sanatani S and Potts JE
DOI: 10.1007/s00246-013-0654-z
PubMed: 23435716
08/2013

The Canadian experience with Durata and Riata ST Optim defibrillator leads: a report from the Canadian Heart Rhythm Society Device Committee.
Heart rhythm
Bennett MT and Ha AC and Exner DV and Tung SK and Parkash R and Connors S and Coutu B and Crystal E and Champagne J and Philippon F and Yee R and Stephenson EA and Nery PB and Essebag V and Healey JS
DOI: 10.1016/j.hrthm.2013.07.050
PubMed: 23973950
08/2013

Electrophysiologic considerations in congenital heart disease and their relationship to heart failure.
The Canadian Journal of Cardiology
Escudero C and Khairy P and Sanatani S
DOI: 10.1016/j.cjca.2013.02.016
PubMed: 23642334
07/2013

Fascicular and nonfascicular left ventricular tachycardias in the young: an international multicenter study.
Journal of cardiovascular electrophysiology
Collins KK and Schaffer MS and Liberman L and Saarel E and Knecht M and Tanel RE and Bradley D and Dubin AM and Paul T and Salerno J and Bar-Cohen Y and Sreeram N and Sanatani S and Pediatric and Congenital Electrophysiology Society
DOI: 10.1111/jce.12105
PubMed: 23437865
06/2013

Failure rate of the Riata lead under advisory: a report from the CHRS Device Committee.
Heart rhythm
Parkash R and Exner D and Champagne J and Mangat I and Thibault B and Healey JS and Tung S and Crystal E and Simpson C and Nery PB and Sterns L and Connors S and Cameron D and Verma A and Krahn A
DOI: 10.1016/j.hrthm.2013.01.018
PubMed: 23333722
05/2013

Inherited heart rhythm disease: negotiating the minefield for the practicing cardiologist.
The Canadian Journal of Cardiology
Krahn AD and Sanatani S and Gardner MJ and Arbour L
DOI: 10.1016/j.cjca.2012.11.009
PubMed: 23261322
01/2013

Postnatal outcome in patients with fetal tachycardia.
Pediatric cardiology
Moodley S and Sanatani S and Potts JE and Sandor GG
DOI: 10.1007/s00246-012-0392-7
PubMed: 22639009
01/2013

Assessment of genetic causes of cardiac arrest.
The Canadian Journal of Cardiology
Bennett MT and Sanatani S and Chakrabarti S and Deyell MW and Krahn AD
DOI: 10.1016/j.cjca.2012.07.002
PubMed: 23200097
01/2013

Overview of antiarrhythmic drug therapy for supraventricular tachycardia in children
Progress in Pediatric Cardiology
Escudero, C. and Carr, R. and Sanatani, S.
DOI: 10.1016/j.ppedcard.2012.11.008
2013

The medical management of pediatric arrhythmias.
Current treatment options in cardiovascular medicine
Escudero C and Carr R and Sanatani S
DOI: 10.1007/s11936-012-0194-5
PubMed: 22907424
10/2012

Epinephrine infusion in the evaluation of unexplained cardiac arrest and familial sudden death: from the cardiac arrest survivors with preserved Ejection Fraction Registry.
Circulation. Arrhythmia and electrophysiology
Krahn AD and Healey JS and Chauhan VS and Birnie DH and Champagne J and Sanatani S and Ahmad K and Ballantyne E and Gerull B and Yee R and Skanes AC and Gula LJ and Leong-Sit P and Gardner M
DOI: 10.1161/circep.112.973230
PubMed: 22944906
10/2012

The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants.
Circulation. Arrhythmia and electrophysiology
Sanatani S and Potts JE and Reed JH and Saul JP and Stephenson EA and Gibbs KA and Anderson CC and Mackie AS and Ro PS and Tisma-Dupanovic S and Kanter RJ and Batra AS and Fournier A and Etheridge SP
DOI: 10.1161/circep.112.972620
PubMed: 22962431
10/2012

Biophysical properties of the aorta and left ventricle and exercise capacity in obese children.
The American journal of cardiology
Harris KC and Al Saloos HA and De Souza AM and Sanatani S and Hinchliffe M and Potts JE and Sandor GG
DOI: 10.1016/j.amjcard.2012.05.019
PubMed: 22728002
09/2012

Neuroblastoma masquerading as supraventricular tachycardia: a case of super sinus tachycardia.
Archives of disease in childhood
Harris KC and Retallack JE and Sanatani S
DOI: 10.1136/archdischild-2011-301327
PubMed: 22267393
06/2012

Congenital long QT 3 in the pediatric population.
The American journal of cardiology
Blaufox AD and Tristani-Firouzi M and Seslar S and Sanatani S and Trivedi B and Fischbach P and Paul T and Young ML and Tisma-Dupanovic S and Silva J and Cuneo B and Fournier A and Etheridge SP
DOI: 10.1016/j.amjcard.2012.01.361
PubMed: 22360817
05/2012

Normal Tp-e values in children.
Anesthesia and analgesia
Sanatani S and Whyte S
DOI: 10.1213/ane.0b013e31823554ac
PubMed: 22184612
01/2012

Recurrent congestive heart failure in a child due to probable myocarditis.
Pediatric cardiology
Lee AF and Chiasson DA and Smythe JF and Sanatani S
DOI: 10.1007/s00246-011-0109-3
PubMed: 21910020
01/2012

Sentinel symptoms in patients with unexplained cardiac arrest: from the cardiac arrest survivors with preserved ejection fraction registry (CASPER).
Journal of cardiovascular electrophysiology
Krahn AD and Healey JS and Simpson CS and Chauhan VS and Birnie DH and Champagne J and Gardner M and Sanatani S and Chakrabarti S and Yee R and Skanes AC and Leong-Sit P and Ahmad K and Sheldon RS
DOI: 10.1111/j.1540-8167.2011.02185.x
PubMed: 21955300
01/2012

Canadian Cardiovascular Society/Canadian Anesthesiologists' Society/Canadian Heart Rhythm Society Joint Position Statement on the Perioperative Management of Patients With Implanted Pacemakers, Defibrillators, and Neurostimulating Devices
Canadian Journal of Cardiology
Healey, J.S. and Merchant, R. and Simpson, C. and Tang, T. and Beardsall, M. and Tung, S. and Fraser, J.A. and Long, L. and van Vlymen, J.M. and Manninen, P. and Ralley, F. and Venkatraghavan, L. and Yee, R. and Prasloski, B. and Sanatani, S. and Philippon, F.
DOI: 10.1016/j.cjca.2011.08.121
2012

The study of antiarrhythmic medications in infancy (SAMIS): A multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants
Circulation: Arrhythmia and Electrophysiology
Sanatani, S. and Potts, J.E. and Reed, J.H. and Saul, J.P. and Stephenson, E.A. and Gibbs, K.A. and Anderson, C.C. and MacKie, A.S. and Ro, P.S. and Tisma-Dupanovic, S. and Kanter, R.J. and Batra, A.S. and Fournier, A. and Blaufox, A.D. and Singh, H.R. and Ross, B.A. and Wong, K.K. and Bar-Cohen, Y. and McCrindle, B.W. and Etheridge, S.P.
DOI: 10.1161/CIRCEP.112.972620
2012

Assessing the knowledge of sudden unexpected death in the young among Canadian medical students and recent graduates: A cross-sectional study
BMJ Open
Huisma, F.F. and Potts, J.E. and Gibbs, K.A. and Sanatani, S.
DOI: 10.1136/bmjopen-2012-001798
2012

PACES/HRS Expert Consensus Statement on the Management of the Asymptomatic Young Patient with a Wolff-Parkinson-White (WPW, Ventricular Preexcitation) Electrocardiographic Pattern: Developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS).
Heart Rhythm
Cohen, M.I. and Triedman, J.K. and Cannon, B.C. and Davis, A.M. and Drago, F. and Janousek, J. and Klein, G.J. and Law, I.H. and Morady, F.J. and Paul, T. and Perry, J.C. and Sanatani, S. and Tanel, R.E.
DOI: 10.1016/j.hrthm.2012.03.050
2012

Erratum: Society position statement Canadian Cardiovascular Society/Canadian Anesthesiologists' Society/Canadian Heart Rhythm Society joint position statement on the perioperative management of patients with implanted pacemakers, defibrillators, and neurostimulating devices (Can J Anesth/J Can Anesth (2012) 59:394-407 doi 10.1007/s12630-012-9678-8)
Canadian Journal of Anesthesia
Healey, J.S. and Merchant, R. and Simpson, C. and Tang, T. and Beardsall, M. and Tung, S. and Fraser, J.A. and Long, L. and Van Vlymen, J.M. and Manninen, P. and Ralley, F. and Venkatraghavan, L. and Yee, R. and Prasloski, B. and Sanatani, S. and Philippon, F.
DOI: 10.1007/s12630-012-9720-x
2012

Canadian Cardiovascular Society/Canadian Anesthesiologists' Society/Canadian Heart Rhythm Society joint position statement on the perioperative management of patients with implanted pacemakers, defibrillators, and neurostimulating devices
Canadian Journal of Anesthesia
Healey, J.S. and Merchant, R. and Simpson, C. and Tang, T. and Beardsall, M. and Tung, S. and Fraser, J.A. and Long, L. and Van Vlymen, J.M. and Manninen, P. and Ralley, F. and Venkatraghavan, L. and Yee, R. and Prasloski, B. and Sanatani, S. and Philippon, F.
DOI: 10.1007/s12630-012-9678-8
2012

Epinephrine infusion in the evaluation of unexplained cardiac arrest and familial sudden death: From the Cardiac Arrest Survivors with Preserved Ejection Fraction Registry
Circulation: Arrhythmia and Electrophysiology
Krahn, A.D. and Healey, J.S. and Chauhan, V.S. and Birnie, D.H. and Champagne, J. and Sanatani, S. and Ahmad, K. and Ballantyne, E. and Gerull, B. and Yee, R. and Skanes, A.C. and Gula, L.J. and Leong-Sit, P. and Klein, G.J. and Gollob, M.H. and Simpson, C.S. and Talajic, M. and Gardner, M.
DOI: 10.1161/CIRCEP.112.973230
2012

Normal Tp-e values in children
Anesthesia and Analgesia
Sanatani, S. and Whyte, S.
DOI: 10.1213/ANE.0b013e31823554ac
2012

Postexertional supraventricular tachycardia in children with catecholaminergic polymorphic ventricular tachycardia.
Case reports in cardiology
Else SD and Potts JE and Sanatani S
DOI: 10.1155/2012/329097
PubMed: 24826246
2012

Isolation and characterization of atrioventricular nodal cells from neonate rabbit heart.
Circulation. Arrhythmia and electrophysiology
Ye Sheng X and Qu Y and Dan P and Lin E and Korthout L and Bradford A and Hove-Madsen L and Sanatani S and Tibbits GF
DOI: 10.1161/circep.111.964056
PubMed: 22002995
12/2011

Prevalence and characteristics of early repolarization in the CASPER registry: cardiac arrest survivors with preserved ejection fraction registry.
Journal of the American College of Cardiology
Derval N and Simpson CS and Birnie DH and Healey JS and Chauhan V and Champagne J and Gardner M and Sanatani S and Yee R and Skanes AC and Gula LJ and Leong-Sit P and Ahmad K and Krahn AD
DOI: 10.1016/j.jacc.2011.04.022
PubMed: 21816308
08/2011

Long QT syndrome.
CMAJ : Canadian Medical Association Journal
Jackson H and Huisman LA and Sanatani S and Arbour LT
DOI: 10.1503/cmaj.100138
PubMed: 21482651
08/2011

A novel mechanism for LQT3 with 2:1 block: a pore-lining mutation in Nav1.5 significantly affects voltage-dependence of activation.
Heart rhythm
Horne AJ and Eldstrom J and Sanatani S and Fedida D
DOI: 10.1016/j.hrthm.2010.12.041
PubMed: 21193062
05/2011

Severe amiodarone-induced hypothyroidism in an infant.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Trudel K and Sanatani S and Panagiotopoulos C
DOI: 10.1097/pcc.0b013e3181e2a388
PubMed: 20453707
01/2011

Short- and long-term outcomes in children undergoing radiofrequency catheter ablation before their second birthday.
The Canadian Journal of Cardiology
Kantoch MJ and Gulamhusein SS and Sanatani S
DOI: 10.1016/j.cjca.2010.12.043
PubMed: 21621374
2011

Response to letter regarding article, complications associated with revision of sprint fidelis leads: Report from the canadian heart rhythm society device advisory committee
Circulation
Parkash, R. and Crystal, E. and Bashir, J. and Simpson, C. and Birnie, D. and Sterns, L. and Exner, D. and Thibault, B. and Connors, S. and Healey, J.S. and Champagne, J. and Cameron, D. and Mangat, I. and Verma, A. and Wolfe, K. and Essebag, V. and Kus, T. and Ayala-Paredes, F. and Davies, T. and Sanatani, S. and Gow, R. and Coutu, B. and Sivakumaran, S. and Stephenson, E. and Krahn, A.
DOI: 10.1161/CIRCULATIONAHA.110.003517
2011

Severe amiodarone-induced hypothyroidism in an infant
Pediatric Critical Care Medicine
Trudel, K. and Sanatani, S. and Panagiotopoulos, C.
DOI: 10.1097/PCC.0b013e3181e2a388
2011

Recommendations for the use of genetic testing in the clinical evaluation of inherited cardiac arrhythmias associated with sudden cardiac death: Canadian cardiovascular society/Canadian heart rhythm society joint position paper
Canadian Journal of Cardiology
Gollob, M.H. and Blier, L. and Brugada, R. and Champagne, J. and Chauhan, V. and Connors, S. and Gardner, M. and Green, M.S. and Gow, R. and Hamilton, R. and Harris, L. and Healey, J.S. and Hodgkinson, K. and Honeywell, C. and Kantoch, M. and Kirsh, J. and Krahn, A. and Mullen, M. and Parkash, R. and Redfearn, D. and Rutberg, J. and Sanatani, S. and Woo, A.
DOI: 10.1016/j.cjca.2010.12.078
2011

Isolation and characterization of atrioventricular nodal cells from neonate rabbit heart
Circulation: Arrhythmia and Electrophysiology
Sheng, X.Y. and Qu, Y. and Dan, P. and Lin, E. and Korthout, L. and Bradford, A. and Hove-Madsen, L. and Sanatani, S. and Tibbits, G.F.
DOI: 10.1161/CIRCEP.111.964056
2011

Echocardiographic tools for pacemaker optimization of ventricular function in an infant following surgical repair for double outlet right ventricle.
The Canadian Journal of Cardiology
Jeewa A and Potts MT and Sanatani S and Duncan WJ
DOI: 10.1016/s0828-282x(10)70472-4
PubMed: 21165368
12/2010

The effects of droperidol and ondansetron on dispersion of myocardial repolarization in children.
Paediatric anaesthesia
Mehta D and Sanatani S and Whyte SD
DOI: 10.1111/j.1460-9592.2010.03408.x
PubMed: 20849495
10/2010

Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of IKs.
The Journal of General Physiology
Eldstrom J and Xu H and Werry D and Kang C and Loewen ME and Degenhardt A and Sanatani S and Tibbits GF and Sanders C and Fedida D
DOI: 10.1085/jgp.200910351
PubMed: 20421371
05/2010

Benign cardiac tumours, malignant arrhythmias.
The Canadian Journal of Cardiology
Myers KA and Wong KK and Tipple M and Sanatani S
DOI: 10.1016/s0828-282x(10)70009-x
PubMed: 20151061
02/2010

Does biventricular pacing improve hemodynamics in children undergoing routine congenital heart surgery?
Pediatric cardiology
Jeewa A and Pitfield AF and Potts JE and Soulikias W and DeSouza ES and Hollinger AJ and Sandor GG and LeBlanc JG and Campbell AM and Sanatani S
DOI: 10.1007/s00246-009-9581-4
PubMed: 19936587
02/2010

A review of sudden unexpected death in the young in British Columbia.
The Canadian Journal of Cardiology
Lim Z and Gibbs K and Potts JE and Sanatani S
DOI: 10.1016/s0828-282x(10)70329-9
PubMed: 20101353
01/2010

Pacemaker therapy of postoperative arrhythmias after pediatric cardiac surgery.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Skippen P and Sanatani S and Froese N and Gow RM
DOI: 10.1097/pcc.0b013e3181ae5b8a
PubMed: 19581822
01/2010

Pacemaker therapy of postoperative arrhythmias after pediatric cardiac surgery
Pediatric Critical Care Medicine
Skippen, P. and Sanatani, S. and Froese, N. and Gow, R.M.
DOI: 10.1097/PCC.0b013e3181ae5b8a
2010

Complications associated with revision of sprint fidelis leads: Report from the canadian heart rhythm society device advisory committee
Circulation
Parkash, R. and Crystal, E. and Bashir, J. and Simpson, C. and Birnie, D. and Sterns, L. and Exner, D. and Thibault, B. and Connors, S. and Healey, J.S. and Champagne, J. and Cameron, D. and Mangat, I. and Verma, A. and Wolfe, K. and Essebag, V. and Kus, T. and Ayala-Paredes, F. and Davies, T. and Sanatani, S. and Gow, R. and Coutu, B. and Sivakumaran, S. and Stephenson, E. and Krahn, A.
DOI: 10.1161/CIRCULATIONAHA.109.924357
2010

Echocardiographic tools for pacemaker optimization of ventricular function in an infant following surgical repair for double outlet right ventricle
Canadian Journal of Cardiology
Jeewa, A. and Potts, M.T. and Sanatani, S. and Duncan, W.J.
DOI: 10.1016/S0828-282X(10)70472-4
2010

A review of sudden unexpected death in the young in British Columbia
Canadian Journal of Cardiology
Lim, Z. and Gibbs, K. and Potts, J.E. and Sanatani, S.
DOI: 10.1016/S0828-282X(10)70329-9
2010

Benign cardiac tumours, malignant arrhythmias
Canadian Journal of Cardiology
Myers, K.A. and Wong, K.K. and Tipple, M. and Sanatani, S.
DOI: 10.1016/S0828-282X(10)70009-X
2010

Cardiac risk assessment before the use of stimulant medications in children and youth.
Paediatrics & Child Health
Bélanger SA and Warren AE and Hamilton RM and Gray C and Gow RM and Sanatani S and Côté JM and Frcpc JL and Leblanc J and Martin S and Miles B and Mitchell C and Gorman DA and Weiss M and Schachar R
DOI: 10.1093/pch/14.9.579
PubMed: 21037835
11/2009

Are implantable loop recorders useful in detecting arrhythmias in children with unexplained syncope?
Pacing and clinical electrophysiology : PACE
Al Dhahri KN and Potts JE and Chiu CC and Hamilton RM and Sanatani S
DOI: 10.1111/j.1540-8159.2009.02486.x
PubMed: 19694968
11/2009

Cardiac risk assessment before the use of stimulant medications in children and youth: A joint position statement by the Canadian Paediatric Society, the Canadian Cardiovascular Society, and the Canadian Academy of Child and Adolescent Psychiatry.
The Canadian Journal of Cardiology
Warren AE and Hamilton RM and Bélanger SA and Gray C and Gow RM and Sanatani S and Côté JM and Lougheed J and LeBlanc J and Martin S and Miles B and Mitchell C and Gorman DA and Weiss M and Schachar R
DOI: 10.1016/s0828-282x(09)70157-6
PubMed: 19898693
11/2009

L’évaluation du risque cardiaque avant l’utilisation de stimulants chez les enfants et les adolescents.
Paediatrics & Child Health
Bélanger S and Warren A and Hamilton R and Gray C and Gow R and Sanatani S and Côté J and Lougheed J and LeBlanc J and Martin S and Miles B and Mitchell C and Gorman D and Weiss M and Schachar R
DOI: 10.1093/pch/14.9.586
11/2009

Diagnosis of postoperative arrhythmias following paediatric cardiac surgery.
Anaesthesia and intensive care
Skippen PW and Sanatani S and Gow RM and Froese N
PubMed: 19775033
09/2009

Systematic assessment of patients with unexplained cardiac arrest: Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER).
Circulation
Krahn AD and Healey JS and Chauhan V and Birnie DH and Simpson CS and Champagne J and Gardner M and Sanatani S and Exner DV and Klein GJ and Yee R and Skanes AC and Gula LJ and Gollob MH
DOI: 10.1161/circulationaha.109.853143
PubMed: 19597050
07/2009

Formation of a national network for rapid response to device and lead advisories: The Canadian Heart Rhythm Society Device Advisory Committee.
The Canadian Journal of Cardiology
Krahn AD and Simpson CS and Parkash R and Yee R and Champagne J and Healey JS and Cameron D and Thibault B and Mangat I and Tung S and Sterns L and Birnie DH and Exner DV and Gardner M
DOI: 10.1016/s0828-282x(09)70502-1
PubMed: 19584969
07/2009

Utilization of a national network for rapid response to the Medtronic Fidelis lead advisory: the Canadian Heart Rhythm Society Device Advisory Committee.
Heart rhythm
Krahn AD and Simpson CS and Parkash R and Yee R and Champagne J and Healey JS and Cameron D and Thibault B and Mangat I and Tung S and Sterns L and Birnie DH and Exner DV and Essebag V
DOI: 10.1016/j.hrthm.2009.01.012
PubMed: 19324305
04/2009

Pediatric nonpost-operative junctional ectopic tachycardia medical management and interventional therapies.
Journal of the American College of Cardiology
Collins KK and Van Hare GF and Kertesz NJ and Law IH and Bar-Cohen Y and Dubin AM and Etheridge SP and Berul CI and Avari JN and Tuzcu V and Sreeram N and Schaffer MS and Fournier A and Tanel RE
DOI: 10.1016/j.jacc.2008.11.019
PubMed: 19232902
02/2009

Bovine aortic arch in association with double inlet left ventricle and pulmonary atresia: a novel association.
Congenital heart disease
Alghamdi MH and Sanatani S
DOI: 10.1111/j.1747-0803.2009.00265.x
PubMed: 19664036
2009

Formation of a national network for rapid response to device and lead advisories: The Canadian Heart Rhythm Society Device Advisory Committee
Canadian Journal of Cardiology
Krahn, A.D. and Simpson, C.S. and Parkash, R. and Yee, R. and Champagne, J. and Healey, J.S. and Cameron, D. and Thibault, B. and Mangat, I. and Tung, S. and Sterns, L. and Birnie, D.H. and Exner, D.V. and Sivakumaran, S. and Davies, T. and Coutu, B. and Crystal, E. and Wolfe, K. and Verma, A. and Stephenson, E.A. and Sanatani, S. and Gow, R. and Connors, S. and Paredes, F.A. and Turabian, M. and Kus, T. and Essebag, V. and Gardner, M.
DOI: 10.1016/S0828-282X(09)70502-1
2009

Cardiac risk assessment before the use of stimulant medications in children and youth: A joint position statement by the Canadian Paediatric Society, the Canadian Cardiovascular Society, and the Canadian Academy of Child and Adolescent Psychiatry
Canadian Journal of Cardiology
Warren, A.E. and Hamilton, R.M. and Bélanger, S.A. and Gray, C. and Gow, R.M. and Sanatani, S. and Côté, J.-M. and Lougheed, J. and LeBlanc, J. and Martin, S. and Miles, B. and Mitchell, C. and Gorman, D.A. and Weiss, M. and Schachar, R.
DOI: 10.1016/S0828-282X(09)70157-6
2009

Systematic assessment of patients with unexplained cardiac arrest: Cardiac arrest survivors with preserved ejection fraction registry (CASPER)
Circulation
Krahn, A.D. and Healey, J.S. and Chauhan, V. and Birnie, D.H. and Simpson, C.S. and Champagne, J. and Gardner, M. and Sanatani, S. and Exner, D.V. and Klein, G.J. and Yee, R. and Skanes, A.C. and Gula, L.J. and Gollob, M.H.
DOI: 10.1161/CIRCULATIONAHA.109.853143
2009

Diagnosis of postoperative arrhythmias following paediatric cardiac surgery
Anaesthesia and Intensive Care
Skippen, P.W. and Sanatani, S. and Gow, R.M. and Froese, N.
DOI: 10.1177/0310057x0903700506
2009

Cardiac risk assessment before the use of stimulant medications in children and youth: A joint position statement by the Canadian Paediatric Society, the Canadian Cardiovascular Society and the Canadian Academy of Child and Adolescent Psychiatry
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Hamilton, R. and Gray, C. and Bélanger, S.A. and Warren, A.E. and Gow, R.M. and Sanatani, S. and Côté, J.-M. and Lougheed, J. and LeBlanc, J. and Martin, S. and Miles, B. and Mitchell, C. and Gorman, D.A. and Weiss, M. and Schachar, R.
2009

Right ventricular tachycardia
Congenital Diseases in the Right Heart
Sanatani, S. and Gross, G.J.
DOI: 10.1007/978-1-84800-378-1_14
2009

The effect of propofol concentration on dispersion of myocardial repolarization in children.
Anesthesia and analgesia
Hume-Smith HV and Sanatani S and Lim J and Chau A and Whyte SD
DOI: 10.1213/ane.0b013e3181815ce3
PubMed: 18713888
09/2008

A KCNQ1 V205M missense mutation causes a high rate of long QT syndrome in a First Nations community of northern British Columbia: a community-based approach to understanding the impact.
Genetics in medicine : official journal of the American College of Medical Genetics
Arbour L and Rezazadeh S and Eldstrom J and Weget-Simms G and Rupps R and Dyer Z and Tibbits G and Accili E and Casey B and Kmetic A and Sanatani S and Fedida D
DOI: 10.1097/gim.0b013e31817c6b19
PubMed: 18580685
07/2008

The challenge of diagnosing arrhythmogenic right ventricular cardiomyopathy in the young.
Pediatric cardiology
Sanatani S and Duncan W and Chan S
DOI: 10.1007/s00246-008-9238-8
PubMed: 18427879
07/2008

Congenital long QT syndrome in children identified by family screening.
The American journal of cardiology
Petko C and Bradley DJ and Tristani-Firouzi M and Cohen MI and Sanatani S and Saarel EV and Albaro CA and Etheridge SP
DOI: 10.1016/j.amjcard.2008.02.068
PubMed: 18549854
06/2008

Invasive measurements of atrioventricular conduction parameters prior to and following ventricular septal defect closure with the amplatzer device.
The Journal of invasive cardiology
Kramoh EK and Dahdah N and Fournier A and Sanatani S and Hosking M and Miró J
PubMed: 18460702
05/2008

Invasive measurements of atrioventricular conduction parameters prior to and following ventricular septal defect closure with the Amplatzer device
Journal of Invasive Cardiology
Kramoh, E.K. and Dahdah, N. and Fournier, A. and Sanatani, S. and Hosking, M. and Miró, J.
2008

Outcome of the Fidelis implantable cardioverter-defibrillator lead advisory: A report from the Canadian Heart Rhythm Society Device Advisory Committee
Heart Rhythm
Krahn, A.D. and Champagne, J. and Healey, J.S. and Cameron, D. and Simpson, C.S. and Thibault, B. and Mangat, I. and Tung, S. and Sterns, L. and Birnie, D.H. and Exner, D.V. and Parkash, R. and Sivakumaran, S. and Davies, T. and Coutu, B. and Crystal, E. and Wolfe, K. and Verma, A. and Stephenson, E.A. and Sanatani, S. and Gow, R. and Connors, S. and Paredes, F.A. and Essebag, V.
DOI: 10.1016/j.hrthm.2008.01.029
2008

A KCNQ1 V205M missense mutation causes a high rate of long QT syndrome in a First Nations community of northern British Columbia: A community-based approach to understanding the impact
Genetics in Medicine
Arbour, L. and Rezazadeh, S. and Eldstrom, J. and Weget-Simms, G. and Rupps, R. and Dyer, Z. and Tibbits, G. and Accili, E. and Casey, B. and Kmetic, A. and Sanatani, S. and Fedida, D.
DOI: 10.1097/GIM.0b013e31817c6b19
2008

Long QT syndrome in children in the era of implantable defibrillators.
Journal of the American College of Cardiology
Etheridge SP and Sanatani S and Cohen MI and Albaro CA and Saarel EV and Bradley DJ
DOI: 10.1016/j.jacc.2007.05.042
PubMed: 17903632
10/2007

A comparison of the effect on dispersion of repolarization of age-adjusted MAC values of sevoflurane in children.
Anesthesia and analgesia
Whyte SD and Sanatani S and Lim J and Booker PD
DOI: 10.1213/01.ane.0000252417.23986.6e
PubMed: 17242080
02/2007

Right ventricular outflow tract tachycardia in children.
The Journal of pediatrics
Harris KC and Potts JE and Fournier A and Gross GJ and Kantoch MJ and Cote JM and Sanatani S
DOI: 10.1016/j.jpeds.2006.08.076
PubMed: 17137900
12/2006

Minimally invasive approach to the child with palpitations.
Expert review of cardiovascular therapy
Rajagopalan K and Potts JE and Sanatani S
DOI: 10.1586/14779072.4.5.681
PubMed: 17081090
09/2006

Sudden unexpected death in children with heart disease.
Congenital heart disease
Sanatani S and Wilson G and Smith CR and Hamilton RM and Williams WG and Adatia I
DOI: 10.1111/j.1747-0803.2006.00014.x
PubMed: 18377551
05/2006

An alternate technique to pacing in complex congenital heart disease: assessment of the left thoracotomy approach.
The Canadian Journal of Cardiology
Roberts AD and Sett S and Leblanc J and Sanatani S
DOI: 10.1016/s0828-282x(06)70264-1
PubMed: 16685311
05/2006

Medications used to manage supraventricular tachycardia in the infant a North American survey.
Pediatric cardiology
Wong KK and Potts JE and Etheridge SP and Sanatani S
DOI: 10.1007/s00246-005-1126-x
PubMed: 16391988
2006

An alternate technique to pacing in complex congenital heart disease: Assessment of the left thoracotomy approach
Canadian Journal of Cardiology
Roberts, A.D. and Sett, S. and Leblanc, J. and Sanatani, S.
DOI: 10.1016/S0828-282X(06)70264-1
2006

Torsades de pointes with sevoflurane [6]
Paediatric Anaesthesia
Whyte, S.D. and Sanatani, S. and Booker, P.D.
DOI: 10.1111/j.1460-9592.2006.01994.x
2006

Dilated cardiomyopathy masquerading as long QT syndrome
Pediatric Cardiology
Walls, J. and Dipchand, A. and Sanatani, S.
DOI: 10.1007/s00246-005-1114-1
2006

Resynchronization therapy in pediatric and congenital heart disease patients: an international multicenter study.
Journal of the American College of Cardiology
Dubin AM and Janousek J and Rhee E and Strieper MJ and Cecchin F and Law IH and Shannon KM and Temple J and Rosenthal E and Zimmerman FJ and Davis A and Karpawich PP and Al Ahmad A and Collins KK
DOI: 10.1016/j.jacc.2005.05.096
PubMed: 16360058
12/2005

Documenting junctional ectopic tachycardia following pediatric open heart surgery.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet
Gengsakul A and Potts JE and Sandhu A and Patterson MW and Sett SS and Taylor G and Sanatani S
PubMed: 16858961
11/2005

Documenting junctional ectopic tachycardia following pediatric open heart surgery.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet
Gengsakul A and Potts JE and Sandhu A and Patterson MW and Sett SS and Taylor G and Sanatani S
PubMed: 16858961
11/2005

Cerebral oxygenation during defibrillator threshold testing of implantable cardioverter defibrillators.
Pacing and clinical electrophysiology : PACE
McNeill E and Gagnon RE and Potts JE and Yeung-Lai-Wah JA and Kerr CR and Sanatani S
DOI: 10.1111/j.1540-8159.2005.09518.x
PubMed: 15955185
06/2005

Anomalous origin of the left coronary artery with diffuse coronary hypoplasia resulting in sudden death.
The Canadian Journal of Cardiology
Ho J and Jevon G and Sanatani S
PubMed: 15917883
05/2005

The protean manifestations of blunt cardiac trauma in children.
Pediatric emergency care
Milligan J and Potts JE and Human DG and Sanatani S
DOI: 10.1097/01.pec.0000159071.62938.5b
PubMed: 15874814
05/2005

The Brugada ECG pattern in a neonate.
Journal of cardiovascular electrophysiology
Sanatani S and Mahkseed N and Vallance H and Brugada R
DOI: 10.1046/j.1540-8167.2005.40607.x
PubMed: 15817096
03/2005

Post-hoc diagnosis of congenital long QT syndrome in patients with tetralogy of Fallot.
Pediatric cardiology
Walls J and Sanatani S and Hamilton R
DOI: 10.1007/s00246-004-0712-7
PubMed: 15793661
2005

Anomalous origin of the left coronary artery with diffuse coronary hypoplasia resulting in sudden death
Canadian Journal of Cardiology
Ho, J. and Jevon, G. and Sanatani, S.
2005

Documenting junctional ectopic tachycardia following pediatric open heart surgery.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet
Gengsakul, A. and Potts, J.E. and Sandhu, A. and Patterson, M.W. and Sett, S.S. and Taylor, G. and Sanatani, S.
2005

Long on QT and low on calcium.
Cardiology in the young
Bradley TJ and Metzger DL and Sanatani S
DOI: 10.1017/s1047951104006134
PubMed: 15680004
12/2004

Coronary vessel involvement by chronic graft-versus-host disease presenting as sudden cardiac death.
Bone marrow transplantation
Prevost D and Taylor G and Sanatani S and Schultz KR
DOI: 10.1038/sj.bmt.1704625
PubMed: 15300232
10/2004

Evolution of heart rate control after transplantation: conduction versus autonomic innervation.
Pediatric cardiology
Sanatani S and Chiu C and Nykanen D and Coles J and West L and Hamilton R
DOI: 10.1007/s00246-003-0387-5
PubMed: 14647999
2004

Long on QT and low on calcium
Cardiology in the Young
Bradley, T.J. and Metzger, D.L. and Sanatani, S.
DOI: 10.1017/S1047951104006134
2004

Use of an implantable loop recorder in the evaluation of children with congenital heart disease.
American heart journal
Sanatani S and Peirone A and Chiu C and Human DG and Gross GJ and Hamilton RM
DOI: 10.1067/mhj.2002.120157
PubMed: 11835044
02/2002

Predictors of refractory tachycardia in infants with supraventricular tachycardia.
Pediatric cardiology
Sanatani S and Hamilton RM and Gross GJ
DOI: 10.1007/s00246-002-1514-4
PubMed: 12189406
2002

Spontaneously terminating apparent ventricular fibrillation during transesophageal electrophysiological testing in infants with Wolff-Parkinson-White syndrome.
Pacing and clinical electrophysiology : PACE
Sanatani S and Saul JP and Walsh EP and Gross GJ
DOI: 10.1046/j.1460-9592.2001.01816.x
PubMed: 11817818
12/2001

Balloon angioplasty of right ventricular outflow tract conduits.
Pediatric cardiology
Sanatani S and Potts JE and Human DG and Sandor GG and Patterson MW and Gordon Culham JA
DOI: 10.1007/s002460010209
PubMed: 11343149
2001

Echocardiography and pulmonary function testing in childhood onset systemic lupus erythematosus
Lupus
Al-Abbad, A.-J.A. and Cabral, D.A. and Sanatani, S. and Sandor, G.G.S. and Seear, M. and Petty, R.E. and Malleson, P.N.
DOI: 10.1191/096120301669980721
2001

Early and intermediate-term complications of self-expanding stents limit its potential application in children with congenital heart disease.
Journal of the American College of Cardiology
Cheung YF and Sanatani S and Leung MP and Human DG and Chau AK and Culham JA
DOI: 10.1016/s0735-1097(99)00644-0
PubMed: 10732902
03/2000

Coil occlusion of the patent ductus arteriosus: lessons learned.
Cardiovascular and interventional radiology
Sanatani S and Potts JE and Ryan A and Sandor GG and Human DG and Culham JA
DOI: 10.1007/s002709910019
PubMed: 10795831
2000

Early and intermediate-term complications of self-expanding stents limits its potential application in children with congenital heart disease
Journal of the American College of Cardiology
Cheung, Y.-F. and Sanatani, S. and Leung, M.P. and Human, D.G. and Chau, A.K.T. and Culham, J.A.G.
DOI: 10.1016/S0735-1097(99)00644-0
2000

Vascular abnormalities in Adams-Oliver syndrome: cause or effect?
American journal of medical genetics
Swartz EN and Sanatani S and Sandor GG and Schreiber RA
DOI: 10.1002/(sici)1096-8628(19990101)82:13.0.co;2-m
PubMed: 9916843
01/1999

Vascular abnormalities in Adams-Oliver syndrome: Cause or effect?
American Journal of Medical Genetics
Swartz, E.N. and Sanatani, S. and Sandor, G.G.S. and Schreiber, R.A.
DOI: 10.1002/(SICI)1096-8628(19990101)82:13.0.CO;2-M
1999

Extracardiac Fontan operation with tube fenestration allowing transcatheter coil occlusion.
The Annals of thoracic surgery
Sanatani S and Sett SS and Human DG and Culham JA and LeBlanc JG
DOI: 10.1016/s0003-4975(98)00560-8
PubMed: 9768957
09/1998

Kawasaki disease in the older child.
Pediatrics
Momenah T and Sanatani S and Potts J and Sandor GG and Human DG and Patterson MW
DOI: 10.1542/peds.102.1.e7
PubMed: 9651459
07/1998

Extracardiac Fontan operation with tube fenestration allowing transcatheter coil occlusion
Annals of Thoracic Surgery
Sanatani, S. and Sett, S.S. and Human, D.G. and Gordon Culham, J.A. and LeBlanc, J.G.
DOI: 10.1016/S0003-4975(98)00560-8
1998

Research

Supraventricular tachycardia (SVT)
Supraventricular tachycardia remains the most common chronic rhythm disturbance. I was the Principal Investigator on a Heart and Stroke funded multi-site study examining two antiarrhythmia medications in infants with this rhythm disturbance. This study was among very few prospective controlled studies in pediatric electrophysiology. This study led to the creation of the International SVT Pediatric SVT Research Interest group, which continues to support pediatric SVT research.

In the realm of SVT, CIHR-funded collaborations with the cardiac basic science group are ongoing, examining mechanisms of post-operative arrhythmias. This group has isolated cells from a neonatal rabbit’s cardiac conduction system. To our knowledge, the isolation of neonatal AV nodal cells had not been done before.

Sudden unexpected death (SUD)
Sudden death affects about 500000 individuals each year in North America. The vast majority of these cases occur in older individuals with coronary artery disease. An important number of cases, however, are due to hidden heart disease, either latent structural disease or primary electrical heart disease. These disorders are typically due to mutations in the genes responsible for the electrical heart beat and corresponding muscle contraction. The abnormalities predispose the individual to potentially lethal cardiac rhythm abnormalities.

I am part of a national research collaboration examining families of SUD victims to identify the cause of SUD in these families. We have many active research collaborations on sudden death in the young. My clinical work in SUD substrates has led to multidisciplinary collaboration with basic scientists, geneticists, genetic counselors and lay personnel. We have described a novel mutation in a Northern British Columbia community predisposing many individuals to SUD. This work has led to further collaboration, grants and ongoing research. We currently lead an international registry on pediatric catecholaminergic polymorphic ventricular tachycardia, a rare, but lethal heart condition.

Working with a group of anesthetists, we examined the effects of anesthetic agents on cardiac repolarization. Abnormalities of repolarization have been linked to sudden death and arrhythmias. This project was one of several projects dealing with cardiac repolarization.

I am a member of the medical advisory for the Sudden Arrhythmia Death Syndromes (SADS) Foundation and serve on the scientific advisory board of the American SADS Foundation. I was the Vice-President of Research for the international Pediatric and Congenital Electrophysiology Society (PACES) prior to serving as president in 2016-17.

Honours & Awards

Resident Research Faculty Mentor of the Year Award, UBC Department of Pediatrics. 2011-2012

Canadian Pacific Has Heart Cardiovascular Award. Heart and Stroke Foundation. Oct 2015

Research Group Members

Harnoor Dhaliwal, Volunteer
Sonia Franciosi, Research Associate
Dania Kallas, Research Coordinator
Melanie Kardel, Research Associate
Abhay Katyal, Research Coordinator
Carson Leach, Research Assistant
Cameron Lee, Volunteer Research Assistant
Christopher Li, Research Assistant
Karam Mandair, Research Assistant
Stella Price, Research Assistant
Samantha Wong, Research Assistant