{"id":320,"date":"2023-03-17T20:19:38","date_gmt":"2023-03-17T20:19:38","guid":{"rendered":"https:\/\/bcchrmicro.wpengine.com\/?page_id=320"},"modified":"2026-03-10T20:44:05","modified_gmt":"2026-03-10T20:44:05","slug":"research","status":"publish","type":"page","link":"https:\/\/www.bcchr.ca\/childhoodcancer\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<div  class=\"fndry-container fndry-responsive-bg fndry-container--full fndry-pt--md-3 fndry-pr--md-3 fndry-pl--md-3 fndry-pb--md-6 fndry-pr--sm-2 fndry-pl--sm-2 fndry-pb--sm-3\" style=\"--fndry-bg:var(--fndry-color-tertiaryLight)\">\n\t<div  class=\"fndry-container fndry-responsive-bg\">\n\t<div class=\"fndry-row fndry-align--center fndry-justify--sm-center fndry-justify--between\">\n\t<div  class=\"fndry-col fndry-responsive-bg fndry-col--6 fndry-col--md-10 fndry-col--sm-12 fndry-pl--2 fndry-pb--5 fndry-pt--5 fndry-pt--md-2 fndry-pb--md-2 fndry-pr--md-0 fndry-pl--md-0\">\n\t<div class=\"breadcrumbs align fndry-pb--2 wp-block-bcn-breadcrumb-trail has-text-color has-background \" vocab=\"https:\/\/schema.org\/\" typeof=\"BreadcrumbList\">\n\t<span><\/span>\n\t<span property=\"itemListElement\" typeof=\"ListItem\"><a property=\"item\" typeof=\"WebPage\" title=\"Go to Michael Cuccione Childhood Cancer Research Program (MCCCRP).\" href=\"https:\/\/www.bcchr.ca\/childhoodcancer\" class=\"home\" ><span property=\"name\">Michael Cuccione Childhood Cancer Research Program (MCCCRP)<\/span><\/a><meta property=\"position\" content=\"1\"><\/span><span property=\"itemListElement\" typeof=\"ListItem\"><a property=\"item\" typeof=\"WebPage\" title=\"Go to News.\" href=\"https:\/\/www.bcchr.ca\/childhoodcancer\/news\/\" class=\"post-root post post-post\" aria-current=\"page\"><span property=\"name\">News<\/span><\/a><meta property=\"position\" content=\"2\"><\/span><\/div>\n<h1 class=\"fndry-heading\">Research<\/h1><p class=\"fndry-paragraph fndry-text-bannerIntro20\">Learn more about our research.<\/p><\/div>\n<div  class=\"fndry-col fndry-responsive-bg fndry-col--5 fndry-col--md-12\">\n\t<figure  class=\"fndry-image\" style=\"--imageWidth:100%;--img-height-all:100%\" aria-labelledby=\"img-\">\n\t\t\t<\/figure>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n<div  class=\"fndry-container fndry-responsive-bg fndry-pt--5 fndry-pb--0 fndry-pr--md-1 fndry-pl--md-1 fndry-pt--md-3 fndry-pb--md-3 fndry-pt--sm-0 fndry-pb--sm-0 fndry-mt--sm-3 fndry-mb--sm-3\">\n\t<div class=\"fndry-row fndry-justify--center\">\n\t<div  class=\"fndry-col fndry-responsive-bg fndry-col--10 fndry-col--sm-12 fndry-col--md-12 fndry-pr--sm-2 fndry-pl--sm-2 fndry-pt--md-4 fndry-pb--md-4 fndry-pr--md-3 fndry-pl--md-3 fndry-d--flex fndry-flex--col fndry-align--start fndry-justify--center\">\n\t<p class=\"fndry-paragraph\">The Michael Cuccione Childhood Cancer Research Program (MCCCRP)\u00a0is generously supported by the Michael Cuccione Foundation. Since its inception in 1997, the Michael Cuccione Foundation has worked diligently to fund childhood cancer research and make a difference in the fight against childhood cancer.<\/p><p class=\"fndry-paragraph\">Our researchers are based at BC Children&#8217;s Hospital and are members of the Childhood Cancer &#038; Blood Research group. We conduct research that improves the lives of children and young adults with cancer and\/or blood disorders, and those undergoing transplantation.<\/p><\/div>\n<\/div><\/div>\n\n\n<div  class=\"fndry-container fndry-responsive-bg fndry-pr--md-3 fndry-pl--md-3 fndry-pr--sm-2 fndry-pl--sm-2\">\n\t<div  class=\"fndry-container fndry-responsive-bg\">\n\t<div class=\"fndry-row fndry-row--gutter fndry-justify--center\">\n\t<div  class=\"fndry-col fndry-responsive-bg fndry-col--8 fndry-col--sm-10 fndry-pb--2\">\n\t<\/div>\n<\/div><\/div>\n<div class=\"fndry-row fndry-row--gutter\">\n\t<div  class=\"fndry-col fndry-responsive-bg fndry-col--12\">\n\t<div  class=\"fndry-query\" id=\"fndry-query-0\"><ul  class=\"fndry-row fndry-row--gutter fndry-post-loop fndry-justify--start fndry-align--stretch fndry-align--sm-start\">\n\t\t\t<li  class=\"fndry-post fndry-post--gutter fndry-col fndry-col--4 fndry-col--md-6 fndry-col--sm-12 fndry-post post-2144 research type-research status-publish has-post-thumbnail hentry\">\n\t\t\t<div  class=\"fndry-post__inner fndry-responsive-bg fndry-pb--2 fndry-align--stretch fndry-align--sm-start fndry-justify--center\">\n\t\t\t\t<div class=\"fndry-post-featured-image fndry-mb--2\" style=\"--imageWidth:100%;--img-height-all:285px;--img-height-md:auto;--img-height-sm:auto\"><img loading=\"lazy\" decoding=\"async\" width=\"900\" height=\"600\" src=\"https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/cell-signaling-genetics.jpg\" class=\"fndry-post-featured-image__img wp-post-image\" aria-hidden=\"true\" style=\"border-radius:0px;--objectFit:cover;--imagePosX:50%;--imagePosY:50%\" srcset=\"https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/cell-signaling-genetics.jpg 900w, https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/cell-signaling-genetics-300x200.jpg 300w, https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/cell-signaling-genetics-768x512.jpg 768w\" sizes=\"(max-width: 900px) 100vw, 900px\" \/><\/div><h3 class=\"fndry-post-title\" style=\"color:var(--fndry-color-secondary)\"><a href=\"https:\/\/www.bcchr.ca\/childhoodcancer\/research\/cell-signaling-and-genetics\/\" target=\"_self\" rel=\"\" class=\"fndry-post-title__link\">Cell Signaling &#038; Genetics<\/a><\/h3><div class=\"fndry-post-excerpt\"><p class=\"fndry-post-excerpt__excerpt\">The objective of the Cell Signaling and Genetics team is to develop new and better treatments for childhood solid tumours and leukemias based on the study of &#8220;signal transduction pathways&#8221; in tumour cells.<\/p><\/div><a  href=\"https:\/\/www.bcchr.ca\/childhoodcancer\/research\/cell-signaling-and-genetics\/\" rel=\"\" class=\"fndry-btn fndry-mt--auto fndry-btn-link\">Learn More<\/a>\t\t\t<\/div>\n\t\t<\/li>\n\t\t\t\t<li  class=\"fndry-post fndry-post--gutter fndry-col fndry-col--4 fndry-col--md-6 fndry-col--sm-12 fndry-post post-2145 research type-research status-publish has-post-thumbnail hentry\">\n\t\t\t<div  class=\"fndry-post__inner fndry-responsive-bg fndry-pb--2 fndry-align--stretch fndry-align--sm-start fndry-justify--center\">\n\t\t\t\t<div class=\"fndry-post-featured-image fndry-mb--2\" style=\"--imageWidth:100%;--img-height-all:285px;--img-height-md:auto;--img-height-sm:auto\"><img loading=\"lazy\" decoding=\"async\" width=\"900\" height=\"600\" src=\"https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/immunity-immune-response-bone-marrow-transplant-.jpg\" class=\"fndry-post-featured-image__img wp-post-image\" aria-hidden=\"true\" style=\"border-radius:0px;--objectFit:cover;--imagePosX:50%;--imagePosY:50%\" srcset=\"https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/immunity-immune-response-bone-marrow-transplant-.jpg 900w, https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/immunity-immune-response-bone-marrow-transplant--300x200.jpg 300w, https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/immunity-immune-response-bone-marrow-transplant--768x512.jpg 768w\" sizes=\"(max-width: 900px) 100vw, 900px\" \/><\/div><h3 class=\"fndry-post-title\" style=\"color:var(--fndry-color-secondary)\"><a href=\"https:\/\/www.bcchr.ca\/childhoodcancer\/research\/immunity-immune-response-and-bone-marrow-transplant\/\" target=\"_self\" rel=\"\" class=\"fndry-post-title__link\">Immunity, Immune Response &#038; Bone Marrow Transplant (I\/IR\/BMT)<\/a><\/h3><div class=\"fndry-post-excerpt\"><p class=\"fndry-post-excerpt__excerpt\">The goal of the Immunity, Immune Response, and BMT research team is to clarify and explain the mechanisms of GVHD prevalent following bone marrow transplants that treat childhood leukemias.<\/p><\/div><a  href=\"https:\/\/www.bcchr.ca\/childhoodcancer\/research\/immunity-immune-response-and-bone-marrow-transplant\/\" rel=\"\" class=\"fndry-btn fndry-mt--auto fndry-btn-link\">Learn More<\/a>\t\t\t<\/div>\n\t\t<\/li>\n\t\t\t\t<li  class=\"fndry-post fndry-post--gutter fndry-col fndry-col--4 fndry-col--md-6 fndry-col--sm-12 fndry-post post-2146 research type-research status-publish has-post-thumbnail hentry\">\n\t\t\t<div  class=\"fndry-post__inner fndry-responsive-bg fndry-pb--2 fndry-align--stretch fndry-align--sm-start fndry-justify--center\">\n\t\t\t\t<div class=\"fndry-post-featured-image fndry-mb--2\" style=\"--imageWidth:100%;--img-height-all:285px;--img-height-md:auto;--img-height-sm:auto\"><img loading=\"lazy\" decoding=\"async\" width=\"900\" height=\"600\" src=\"https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/mcccrp-clinical-research.jpg\" class=\"fndry-post-featured-image__img wp-post-image\" aria-hidden=\"true\" style=\"border-radius:0px;--objectFit:cover;--imagePosX:50%;--imagePosY:50%\" srcset=\"https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/mcccrp-clinical-research.jpg 900w, https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/mcccrp-clinical-research-300x200.jpg 300w, https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2025\/12\/mcccrp-clinical-research-768x512.jpg 768w\" sizes=\"(max-width: 900px) 100vw, 900px\" \/><\/div><h3 class=\"fndry-post-title\" style=\"color:var(--fndry-color-secondary)\"><a href=\"https:\/\/www.bcchr.ca\/childhoodcancer\/research\/clinical-research\/\" target=\"_self\" rel=\"\" class=\"fndry-post-title__link\">Clinical Research<\/a><\/h3><div class=\"fndry-post-excerpt\"><p class=\"fndry-post-excerpt__excerpt\">Our researchers coordinate and provide leadership for the development of clinical phase I and phase II treatment protocols, utilizing agents identified by the basic\/translational component of the MCCCRP and the Childhood Cancer &#038; Blood Research Group.<\/p><\/div><a  href=\"https:\/\/www.bcchr.ca\/childhoodcancer\/research\/clinical-research\/\" rel=\"\" class=\"fndry-btn fndry-mt--auto fndry-btn-link\">Learn More<\/a>\t\t\t<\/div>\n\t\t<\/li>\n\t\t<\/ul>\n<\/div><\/div>\n<\/div><\/div>\n\n\n<div  class=\"fndry-container fndry-responsive-bg fndry-container--full fndry-pt--md-3 fndry-pr--md-3 fndry-pl--md-3 fndry-pb--md-6 fndry-pr--sm-2 fndry-pl--sm-2\" style=\"--fndry-bg:var(--fndry-color-light)\">\n\t<div  class=\"fndry-container fndry-responsive-bg\">\n\t<div class=\"fndry-row fndry-align--center fndry-justify--sm-center fndry-justify--between\">\n\t<div  class=\"fndry-col fndry-responsive-bg fndry-col--6 fndry-col--md-10 fndry-col--sm-12 fndry-pl--2 fndry-pb--5 fndry-pt--5 fndry-pt--md-2 fndry-pb--md-2\">\n\t<h2 class=\"fndry-heading\" style=\"color:var(--fndry-color-secondary)\">Contact Us<\/h2><p class=\"fndry-paragraph fndry-text-intro18\">Contact us with your inquiries.<\/p><a  href=\"https:\/\/www.bcchr.ca\/childhoodcancer\/contact\/\" rel=\"\" id=\"fndry-block-64b567d42514c\" class=\"fndry-btn fndry-btn-secondaryButtonWArrow\">Contact<\/a><\/div>\n<div  class=\"fndry-col fndry-responsive-bg fndry-col--5 fndry-d--md-none\">\n\t<figure  class=\"fndry-image fndry-mb--0\" style=\"--imageWidth:100%;--img-height-all:100%\" aria-labelledby=\"img-2546\">\n\t<img loading=\"lazy\" decoding=\"async\" width=\"960\" height=\"814\" src=\"https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2026\/01\/bc-childrens-hospital-research-institute.jpg\" class=\"fndry-image__img\" aria-hidden=\"true\" role=\"presentation\" style=\"--borderRadius:0px;--objectFit:cover;--imagePosX:50%;--imagePosY:50%\" srcset=\"https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2026\/01\/bc-childrens-hospital-research-institute.jpg 960w, https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2026\/01\/bc-childrens-hospital-research-institute-300x254.jpg 300w, https:\/\/www.bcchr.ca\/childhoodcancer\/files\/2026\/01\/bc-childrens-hospital-research-institute-768x651.jpg 768w\" sizes=\"(max-width: 960px) 100vw, 960px\" \/>\t\t<\/figure>\n<\/div>\n<\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_lmt_disableupdate":"","_lmt_disable":"","inline_featured_image":false,"footnotes":"","fndry_alternate_title":"Alternate Title!"},"class_list":["post-320","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.bcchr.ca\/childhoodcancer\/wp-json\/wp\/v2\/pages\/320","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bcchr.ca\/childhoodcancer\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bcchr.ca\/childhoodcancer\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bcchr.ca\/childhoodcancer\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bcchr.ca\/childhoodcancer\/wp-json\/wp\/v2\/comments?post=320"}],"version-history":[{"count":5,"href":"https:\/\/www.bcchr.ca\/childhoodcancer\/wp-json\/wp\/v2\/pages\/320\/revisions"}],"predecessor-version":[{"id":2622,"href":"https:\/\/www.bcchr.ca\/childhoodcancer\/wp-json\/wp\/v2\/pages\/320\/revisions\/2622"}],"wp:attachment":[{"href":"https:\/\/www.bcchr.ca\/childhoodcancer\/wp-json\/wp\/v2\/media?parent=320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}