{"id":2648,"date":"2025-12-16T23:14:55","date_gmt":"2025-12-16T23:14:55","guid":{"rendered":"https:\/\/www.bcchr.ca\/childrens-heart-centre-research\/?post_type=research&p=2648"},"modified":"2026-06-17T21:27:21","modified_gmt":"2026-06-17T21:27:21","slug":"heart-rhythm-studies","status":"publish","type":"research","link":"https:\/\/www.bcchr.ca\/childrens-heart-centre-research\/research\/heart-rhythm-studies\/","title":{"rendered":"Heart Rhythm Studies"},"content":{"rendered":"
\n\t
\n\t
\n\t
\n\t
\n\t<\/span>\n\tChildren\u2019s Heart Centre Research<\/span><\/a><\/span><\/div>\n

Heart Rhythm Studies<\/h1><\/div>\n
\n\t
\n\t<\/figure>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n
\n\t
\n\t
\n\t<\/div>\n
\n\t

International Pediatric CPVT Registry<\/strong>

Health information is being collected on CPVT, a disorder which causes individuals\u2019 hearts to beat very fast and irregularly when they are experiencing some kind of strong emotion or when they\u2019re engaging in physical activity. This information from children and families around the world will be used to find specific signs to help doctors predict who is at risk for this heart disorder.<\/p><\/div>\n

\n\t
Who can participate?<\/h5>
    \n\t\t\t\n\t\t\t<\/i>\t\t<\/span>\n\tAnyone diagnosed with CPVT at age 19 or younger and their first-degree relatives (biological mother, father, full siblings, and children).<\/li>\n<\/ul><\/div>\n<\/div><\/div>\n\n\n
    \n\t
    \n\t
    \n\t<\/div>\n
    \n\t

    Neurologic and Cardiac Phenotype in Patients with CPVT<\/strong><\/strong>

    Researchers have noticed that some people with CPVT \u2013 especially those with variants in RYR2<\/em> \u2013 may also experience neurologic or neurodevelopmental challenges (like seizures, learning differences, attention challenges, or autism spectrum traits). This study aims to screen for neurodevelopmental disorders (NDD) in a large group of children with CPVT and better understand the cardiac course of CPVT in children who may also have NDD features.<\/p><\/div>\n

    \n\t
    Who can participate?<\/h5>
      \n\t\t\t\n\t\t\t<\/i>\t\t<\/span>\n\tAnyone between the ages of 3 and 19 who has been diagnosed with CPVT before age 18.<\/li>\n<\/ul><\/div>\n<\/div><\/div>\n\n\n
      \n\t
      \n\t
      \n\t<\/div>\n
      \n\t

      BC Inherited Arrhythmia Research Program Data Registry<\/strong>

      A collection of health information from patients across BC with one of the following inherited heart rhythm problems: arrhythmogenic right ventricular cardiomyopathy (ARVC), hypertrophic cardiomyopathy (HCM), long QT syndrome (LQTS), short QT syndrome (SQTS), Brugada syndrome (BrS), catecholaminergic polymorphic ventricular tachycardia (CPVT). These patients are also enrolled in the HiRO (Hearts in Rhythm Organization) registry, which includes CASPER (people who have had a sudden cardiac arrest or sudden unexpected death, as well as their first-degree family members). This information will help researchers and doctors learn more about these problems and put together better treatment plans.<\/p><\/div>\n

      \n\t
      Who can participate?<\/h5>
        \n\t\t\t\n\t\t\t<\/i>\t\t<\/span>\n\tAnyone under the age of 19 with an inherited arrhythmia and their first-degree relatives (biological mother, father, full siblings, and children).<\/li>\n<\/ul><\/div>\n<\/div><\/div>\n\n\n
        \n\t
        \n\t
        \n\t<\/div>\n
        \n\t

        Identification and Functional Characterization of Mutations Implicated in Inherited Arrhythmia Syndromes<\/strong><\/strong><\/strong>

        This study aims to better understand new changes in genes (mutations) and how they contribute to inherited arrhythmia syndromes. In collaboration with leading scientists in the field, we will examine how these mutations change the function of the heart. Results will help us better understand how mutations contribute to heart rhythm disorders.<\/p><\/div>\n

        \n\t
        Who can participate?<\/h5>