The Analytical Core for Metabolomics and Nutrition (ACMaN) has a wide variety of instrumentation and the ability to analyze many types of compounds with excellent sensitivity requiring small sample sizes. Samples can be from any animal, plant or food source. Examples are plasma, serum, red blood cells, white blood cells, milk, saliva, tissues, cells, membrane fractions and plant vegetable oils.
The facility has gas chromatographs, high pressure liquid chromatographs and various detectors (photodiode array, evaporative light scattering, fluorescence, mass spectrometer), sample preparation equipment (speedvac, freeze-dryer, mixers, centrifuges, etc.), plate readers, and automated analyzers for clinical and biochemical analytes of interest.
Two state-of-the-art systems for targeted and untargeted metabolomics analysis are highlights of the core’s analytical portfolio. The core also includes a gas chromatograph mass spectrometer (GC-MS) with Waters TargetLynx principle component software and an Agilent ultra-high pressure liquid chromatograph with quadrupole time of flight mass spectrometer (UPLC-QTOF), as well as Mass Profiler Professional metabolomics software and pathway analysis.
For more information on services and facilities see the ACMaN website.