Catherine Biggs

MSc, MD, BSc

Investigator, BC Children's Hospital

My research focuses on primary immune deficiency and dysregulatory syndromes (PIDs). These are conditions caused by genetic changes that affect how the immune system develops or functions. Those affected by PIDs may suffer from recurrent infections, as well as excessive inflammation caused by difficulties in controlling immune responses, such as severe allergic disease or autoimmunity. The wide ranging clinical manifestations makes it challenging to recognize PIDs, leading to delays in diagnosis and treatment. The goal of my research program is to improve health outcomes for patients suffering from PIDs using a translational approach that integrates clinical and laboratory-based research methods. We aim to improve our understanding of these conditions and to identify approaches (such as screening tools) that can lead to earlier diagnosis and treatment of those suffering from PIDs.