Philipp Lange

(he/him)
PhD

Investigator, Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital
Canada Research Chair in Translational Proteogenomics of Pediatric Malignancies

My research team strives to develop new diagnostic and therapeutic approaches to detect and treat children suffering from cancer earlier, better and with reduced impact on their life.

The fundamental question is how cancer cells are different from healthy, normal cells? If we understand this we will be able to better detect and kill cancer while leaving the rest of the body untouched.

Our research focuses on proteins, the structural and functional building blocks of a cell. To do this we combine genomics and proteomics, a technology that enables us to monitor all of the proteins in our body and detect how they are changed in childhood cancer. We then use computational approaches to further analyze and integrate our findings and to make them accessible to clinicians and fellow scientists around the world.

Academic Affiliations

  • Associate Professor, , Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia
  • Research Theme: Childhood Diseases
  • Research Group(s): Childhood Cancer and Blood Research; Immunity in Health and Disease; Rare Diseases

Contact Information

Assistant

Brenda Tse

brenda.tse@ubc.ca

Location

950 West 28th Avenue, Vancouver, British Columbia, Canada, V5Z 4H4

Grants

"Proteolytic protein termini as a new strategy for cancer cell-specific therapy," Innovation Grant, Canadian Cancer Society, 2016-2018

"Bioinformatics resources for genomewide assessment of protein function at the proteoform level," NSERC Discovery Grant, $28,000/ year, 2018-2023

Honours & Awards

Michael Smith Health Foundation Research Scholar Award (2016)

Canada Research Chair Tier 2 Award in Translational Proteomics of Childhood

Malignancies (2015-2020)

Feodor Lynen Research Fellowship for Postdoctoral Research (Alexander von Humboldt Foundation) (2009-2011)

Joint Michael Smith Foundation for Health Research & Breast Cancer Society of Canada Research Award (2011-2012)

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