Claire Gowdy

MSc, BMBS

Investigator and Nuclear Medicine Physician, BC Children's Hospital

Dr. Gowdy is actively involved with national and international bodies working to harmonize the staging and response criteria for childhood cancers, in particular, Hodgkin lymphoma using functional imaging techniques such as PET/CT.

Academic Affiliations

  • Clinical Associate Professor, , Department of Radiology, Faculty of Medicine, University of British Columbia
  • Research Theme: Evidence to Innovation
  • Research Group(s): Clinical Practice, Outcomes and Innovation

Contact Information

Location

4480 Oak Street, Vancouver, British Columbia, Canada, V6H 1N4

Imaging pitfalls in pediatric, adolescent, and young adult Hodgkin lymphoma: a SEARCH for CAYAHL initiative to bridge multidisciplinary patient care

JNCI: Journal of the National Cancer Institute

Nawar Dakhallah and Jonas Steglich and Claire Gowdy and Sarah A Milgrom and Adina L Alazraki and Sharon M Castellino and Karin Dieckmann and Jamie E Flerlage and Mallorie B Heneghan and Kara M Kelly and Hollie A Lai and Christine Mauz-Krholz and Kathleen M McCarten and Reena Pabari and Monica Palese and Lars Kurch and Dietrich Stoevesandt and Jennifer Seelisch and Stephan D Voss

DOI: 10.1093/jnci/djag016

01 / 2026

Enhancing Radiotherapy Quality Assurance in Lymphoma: A Rigorous Real-Time Central Review Process in AHOD2131

International Journal of Radiation Oncology Biology Physics

01 / 2026

Prognostic role of PET/CT volumetric parameters in paediatric Hodgkin lymphoma: A systematic review and expert recommendations from the International SEARCH for CAYAHL Group

British Journal of Haematology

S. Claire Gowdy and Jamie E. Flerlage and Jennifer Seelisch and Monica Palese and Tyler Bradshaw and Sharon M. Castellino and Steve Cho and Karin Dieckmann and Bradford S. Hoppe and Scott Howard and Kara M. Kelly and Lars Kurch and Hollie A. Lai and Egesta Lopci and John T. Lucas, Jr. and Christine Mauz-Krholz and Kathleen M. McCarten and Neeta Pandit-Taskar and Heiko Schder and Jonas Steglich and Dietrich Stoevesandt and Stephan D. Voss and Sarah A. Milgrom

DOI: 10.1111/bjh.70329

01 / 2026

mTOR Inhibition in the Management of Recurrent Metastatic Solid Pseudopapillary Tumor of the Pancreas"

Pediatric Blood and Cancer

Claire Gowdy

01 / 2026

Physician-in-the-loop active learning in radiology artificial workflows: opportunities, challenges, and future directions

AJR

Claire Gowdy

11 / 2025

Development of lesion and organ negative cast modelling technique for quality assurance and optimization of nuclear medicine images

Communications Medicine

Fedrigo, R. and Coope, R.J.N. and Chauss{\'e}, G. and Bloise, I. and Gowdy, C. and B{\'e}nard, F. and Rahmim, A. and Uribe, C.F.

DOI: 10.1038/s43856-025-01009-z

Generalizability of an Adult-Trained Lymphoma PET/CT Metabolic Tumor Volume Segmentation Model to Pediatric Hodgkin Lymphoma Patients. Fereshteh Yousefirizi, Xin Tie, Tyler J. Bradshaw, Steve Cho, Scott Perlman, Muheon Shin, Sharon Castellino, Kara Kelly, Claire Gowdy, Christine Lam, Peyman Sheikhzadeh, Saeed Farzanehfar, Carlos F. Uribe, Arman Rahmim, EANM2024

EANM

10 / 2024

Evaluating Outcome Prediction via Baseline, End-of-Treatment, and Delta Radiomics on PET-CT Images of Primary Mediastinal Large B-Cell Lymphoma

Cancers

Fereshteh Yousefirizi and Claire Gowdy and Ivan S. Klyuzhin and Maziar Sabouri and Petter Tonseth and Anna R. Hayden and Donald Wilson and Laurie H. Sehn and David W. Scott and Christian Steidl and Kerry J. Savage and Carlos F. Uribe and Arman Rahmim

DOI: 10.3390/cancers16061090

03 / 2024

Comprehensive framework for evaluation of deep neural networks in detection and quantification of lymphoma from PET/CT images: clinical insights, pitfalls, and observer agreement analyses

arXiv

Ahamed, S. and Xu, Y. and Kurkowska, S. and Gowdy, C. and Joo, H.O. and Bloise, I. and Wilson, D. and Martineau, P. and Bnard, F. and Yousefirizi, F. and Dodhia, R. and Lavista, J.M. and Weeks, W.B. and Uribe, C.F. and Rahmim, A.

DOI: 10.48550/arXiv.2311.09614

Development of scalable lymphatic system in the 4D XCAT phantom: Application to quantitative evaluation of lymphoma PET segmentations

Medical Physics

Fedrigo, R. and Segars, W.P. and Martineau, P. and Gowdy, C. and Bloise, I. and Uribe, C.F. and Rahmim, A.

DOI: 10.1002/mp.15963

Convolutional neural network with a hybrid loss function for fully automated segmentation of lymphoma lesions in FDG PET images

arXiv

Yousefirizi, F. and Dubljevic, N. and Ahamed, S. and Bloise, I. and Gowdy, C. and Hyun, J.O. and Farag, Y. and de Schaetzen, R. and Martineau, P. and Wilson, D. and Uribe, C.F. and Rahmim, A.

DOI: 10.48550/arXiv.2208.00274

A cascaded deep network for automated tumor detection and segmentation in clinical PET imaging of diffuse large B-cell lymphoma

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Ahamed, S. and Dubljevic, N. and Bloise, I. and Gowdy, C. and Martineau, P. and Wilson, D. and Uribe, C.F. and Rahmim, A. and Yousefirizi, F.

DOI: 10.1117/12.2612684

Metastatic Adamantinoma of the Femur on FDG PET/CT: Atypical Presentation of a Rare Disease

Clinical Nuclear Medicine

Martineau, P. and Bloise, I. and Gowdy, C. and Worsley, D.

DOI: 10.1097/RLU.0000000000003508

Development of the lymphatic system in the 4D XCAT phantom

arXiv

Fedrigo, R. and Segars, W.P. and Martineau, P. and Gowdy, C. and Bloise, I. and Uribe, C.F. and Rahmim, A.

DOI: 10.48550/arxiv.2107.11429

HSCT provides effective treatment for lymphoproliferative disorders in children with primary immunodeficiency

Journal of Allergy and Clinical Immunology

Prunotto, G. and Offor, U.T. and Samarasinghe, S. and Wynn, R. and Vora, A. and Carpenter, B. and Gowdy, C. and McHugh, K. and Windebank, K.P. and Rovelli, A.M. and Slatter, M.A. and Gennery, A.R. and Veys, P. and Bacon, C.M. and Bomken, S. and Lucchini, G.

DOI: 10.1016/j.jaci.2020.03.043

Can quantitative MRI be used in the clinical setting to quantify the impact of intra-articular glucocorticoid injection on synovial disease activity in juvenile idiopathic arthritis?

Pediatric Rheumatology

Bennett, J.L. and Wood, A. and Smith, N. and Mistry, R. and Allen, K. and Jandial, S. and Tuckett, J.D. and Gowdy, S.C. and Foster, H.E. and McErlane, F. and Hollingsworth, K.G.

DOI: 10.1186/s12969-019-0377-7

Predictive Accuracy of Chest Radiographs in Diagnosing Tachypneic Children

Indian Journal of Pediatrics

Seear, M. and Awasthi, S. and Gowraiah, V. and Kapoor, R. and Awasthi, A. and Verma, A. and Al-Shabibi, S. and Gowdy, C.

DOI: 10.1007/s12098-016-2057-7

Radiological prevalence of superior and posterior semicircular canal dehiscence in children

International Journal of Pediatric Otorhinolaryngology

Saxby, A.J. and Gowdy, C. and Fandio, M. and Chadha, N.K. and Kozak, F.K. and Sargent, M.A. and Lea, J.

DOI: 10.1016/j.ijporl.2015.01.001

Hydrocolpos or hematocolpos?

American Journal of Roentgenology

Paterson, A. and Gowdy, S.C. and Sweeney, L.E.

DOI: 10.2214/AJR.11.7691

SEARCH for CAYAHL

As part of this International collaborative group, Dr. Gowdy is leading a systematic review into the role of metabolic PET parameters to act as a biomarker of disease for children and young adults with Hodgkin lymphoma to aid upfront risk stratification and direct clinicians to those high-risk individuals who may benefit from intensification of therapy.

PETool

Train and validate an automated segmentation technique using an AI tool developed at UBC to delineate disease in children and young adults with lymphoma. Use the segmentations to calculate metabolic PET parameters and radiomic features as we work to identify biomarkers of disease which can stage and evaluate response of disease to therapy.

Honours & Awards

2025 - Patient Champion, Medical Staff Committee

Our Research

At BC Children’s, we are making discoveries that save lives and transform health care for children in our province and around the world. Our research portfolio includes basic, clinical, population, and public health research.

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