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DOI: 10.1111/bjh.70157Supportive Care in Cancer
Mehrdadi, I. and Patel, P. and Robinson, P.D. and Mark, C. and Yan, A.P. and Alexander, S. and Aitcheson, M. and Cook, S. and Cox, S. and Gibson, P. and Johnston, D.L. and Koo, A. and Seelisch, J. and Tomlinson, D. and Dupuis, L.L. and Sung, L.
DOI: 10.1007/s00520-025-09693-2New England Journal of Medicine
Gupta, S. and Rau, R.E. and Kairalla, J.A. and Rabin, K.R. and Wang, C. and Angiolillo, A.L. and Alexander, S. and Carroll, A.J. and Conway, S. and Gore, L. and Kirsch, I. and Kubaney, H.R. and Li, A.M. and McNeer, J.L. and Militano, O. and Miller, T.P. and Moyer, Y. and O?Brien, M.M. and Okada, M. and Reshmi, S.C. and Shago, M. and Wagner, E. and Winick, N. and Wood, B.L. and Haworth?Wright, T. and Zaman, F. and Zugmaier, G. and Zupanec, S. and Devidas, M. and Hunger, S.P. and Teachey, D.T. and Raetz, E.A. and Loh, M.L.
DOI: 10.1056/NEJMoa2411680Pediatric Blood and Cancer
Santacroce, S.J. and Beauchemin, M.P. and Ponce, O. and Ji, L. and Ramakrishnan, S. and Bona, K. and Mu{\~n}eton-Casta{\~n}o, Y. and Robles, J.M. and Vargas, S. and De Los Santos, C. and Fisher, B. and Alexander, S. and Sung, L. and Parsons, S.K.
DOI: 10.1002/pbc.31710Pediatric Blood and Cancer
Shapiro, J.R. and Shapiro, G.K. and Gupta, S. and Alexander, S. and Science, M. and Watts, T.H. and Bolotin, S.
DOI: 10.1002/pbc.31696Emerging Infectious Diseases
Dhabaan, G. and Jamal, H. and Ouellette, D. and Alexander, S. and Arane, K. and Campigotto, A. and Tadros, M. and Pich{\'e}-Renaud, P.-P.
DOI: 10.3201/eid3005.231558Supportive Care in Cancer
Mark, C. and Yan, A.P. and Robinson, P.D. and Alexander, S. and Aitcheson, M. and Cox, S. and Gibson, P. and Johnston, D.L. and Koo, A. and Seelisch, J. and Tomlinson, D. and Dupuis, L.L. and Sung, L.
DOI: 10.1007/s00520-024-08612-1Pediatrics
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DOI: 10.1542/peds.2024-066842Frontiers in Immunology
Alexander, S. and Harker-Murray, P. and Hayashi, R.J.
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Ross, S. and Drynan-Arsenault, J. and Peirce, M. and Williams, M. and Alexander, S.
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Roth, M.E. and Parsons, S.K. and Ganz, P.A. and Wagner, L.I. and Hinds, P.S. and Alexander, S. and Bingen, K. and Bober, S.L. and Brackett, J. and Cella, D. and Henry, N.L. and Indelicato, D.J. and Johnson, R.H. and Miller, T.P. and Rosenberg, S.M. and Schmitz, K.H. and Thanarajasingam, G. and Reeve, B.B. and Salsman, J.M.
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DOI: 10.1200/JCO.22.02224Supportive Care in Cancer
Kilfoy, A. and Panesar, P. and Hashemi, E. and Masama, T. and Pereira, M. and Liu, W. and Alexander, S. and Korenblum, C. and Jibb, L.A.
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Kilfoy, A. and Panesar, P. and Hashemi, E. and Masama, T. and Pereira, M. and Liu, W. and Alexander, S. and Korenblum, C. and Jibb, L.
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Joseph-Frederick, Z. and Keis, J. and Green, G. and Petrazzini, A. and Alexander, S. and Kovacevic, A. and Oei, K. and Sung, L.
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Mathews, N. and Alodan, K. and Kuehne, N. and Widger, K. and Locke, M. and Fung, K. and Gandhi, S. and McLean, J. and Hossain, A. and Alexander, S.
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El-Mallawany, N.K. and Alexander, S. and Fluchel, M. and Hayashi, R.J. and Lowe, E.J. and Giulino-Roth, L. and Wistinghausen, B. and Hermiston, M. and Allen, C.E.
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Sgro, J.M. and Campisi, E.S. and Selvam, S. and Greer, M.-L.C. and Alexander, S. and Ngan, B. and Campisi, P.
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Gupta, S. and Sutradhar, R. and Alexander, S. and Science, M. and Lau, C. and Nagamuthu, C. and Agha, M. and Nathan, P.C. and Hodgson, D.
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Jibb, L.A. and Nanos, S.M. and Alexander, S. and Malfitano, C. and Rydall, A. and Gupta, S. and Schimmer, A.D. and Zimmermann, C. and Hales, S. and Nissim, R. and Marmar, C. and Schultebraucks, K. and Mah, K. and Rodin, G.
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Gupta, S. and Alexander, S. and Pole, J.D. and Sutradhar, R. and Crump, M. and Nagamuthu, C. and Baxter, N.N. and Nathan, P.C.
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Lusher, J. and Pipe, S.W. and Alexander, S. and Nugent, D.
DOI: 10.1111/j.1365-2516.2009.02123.xHaemophilia
Metjian, A.D. and Wang, C. and Sood, S.L. and Cuker, A. and Peterson, S.M. and Soucie, J.M. and Konkle, B.A. and Boyd, M. and Roy, G. and Forman, E. and Marandola, J. and Homans, A.C. and Granat, M. and Lusher, J. and Fleming, P. and DiMichele, D. and Goldberg, I. and Saidi, P. and Schwartz, R. and Desposito, F. and Joseph, D. and Kouides, P.A. and La Franco, J. and Coyle, T. and Dhar, N. and Porter, J. and Frank, M. and Lipton, R. and Bosch, M. and Holmberg, R.P. and Menza, L. and Cohen, A. and White, E. and Guerrera, M. and Guelcher, C. and Kessler, C. and Jacobs, H. and Massey, G. and Nolte, M. and Werner, E. and Stewart, K. and Ragni, M. and Jaworski, K. and Rogers, J.S. and Webber, S. and Jubelirer, S. and Arden, D. and Casella, J. and Underland, T. and Panckeri, K. and Palumbo, L. and Sabio, H. and Smith, A. and Sharma, V. and Ashby, P. and Radulescu, V. and Hanna, W. and Zimmerman, C. and Neff, A. and Hudson, M.G. and Reiss, U. and Grant, R. and Key, N. and Nielsen, B. and Dunn, A. and Gutting, K. and Watts, R. and Noa, M.C. and Abshire, T. and Bryant, C. and Ameri, A. and Crenshaw, V. and Kuriakose, P. and Lambing, A. and Heggie, G. and Kovats-Bell, S. and Inoue, S. and Ruff, J.A. and Mitchell, D. and Sandon-Kleiboer, E. and Kraut, E. and Witkoff, W. and Gruppo, R. and Chambers, A. and Kerlin, B. and Lupia, C. and French, J. and Hibner, S. and Shapiro, A. and May, S. and Alexander, S. and Hopewell, S. and Bockenstedt, P. and Pipe, S. and Mathis, D. and Zakarija, A. and Harris, S. and Thompson, A. and Allen, G.A. and Brummel, A.T. and Tarantino, M. and Riedel, A. and Reding, M. and Curoe, S. and Pruthi, R. and Schmidt, K. and Kralovetz, K. and Charles, J. and Diamond, C. and Drozdowicz, P. and Gill, J.C. and Haar, J. and Hoots, W.K. and Gonzalez, V. and Leissinger, C. and Schmidt, C.V. and Stine, K. and Eckert, G. and Sexauer, C. and Kiplinger, F. and Amerson, P. and Johnson, E. and Buchanan, G. and Torres, R. and DiPaola, J. and Lammer, M. and Wicklund, B. and Nelson, D. and Haire, W.D. and Hanlon, E. and Manco-Johnson, M. and Geraghty, S. and Yaish, H. and Green, J. and Young, G. and McGinty, K. and Herbst, K. and Glass, C. and Glader, B. and Zoland, J.M. and Medeiros, D. and Omatsu, D.A. and Ducore, J. and Herr, M. and Koerper, M. and Karp, S. and Lovejoy, A.E. and Farrow, K. and Ewing, N. and Pullens, L. and Meadows, L. and Tackney, A. and Mignacca, R. and Patterson, F. and Bernstein, J. and Berkowitz, B. and Thompson, A.R. and Brower, C. and Recht, M. and Granger, K. and Schulz, L. and Stewart, A.
DOI: 10.1111/j.1365-2516.2009.02025.xPediatric Blood and Cancer
Li, X. and Alexander, S.
DOI: 10.1002/pbc.21816Journal of Pediatric Hematology Oncology
Alexander, S. and Hopewell, S. and Hunter, S. and Chouksey, A.
DOI: 10.1097/MPH.0b013e31815cf742Clinical Pediatrics
Shah, M.D. and O{'}Riordan, M.A. and Alexander, S.W.
DOI: 10.1177/000992280604500407Oncology an Evidence Based Approach
Strunk, C.J. and Alexander, S.W.
DOI: 10.1007/0-387-31056-8_62Pediatric Blood and Cancer
Palmert, M.R. and Alexander, S.W. and Goorin, A.M.
DOI: 10.1002/pbc.10320Blood
Fleming, M.D. and Pinkus, J.L. and Alexander, S.W. and Tam, C. and Loda, M. and Sallan, S.E. and Nichols, K.E. and Carpentieri, D.F. and Pinkus, G.S. and Rollins, B.J.
DOI: 10.1182/blood.V101.7.2473Journal of Pediatric Hematology Oncology
Alexander, S.W. and Wade, K.C. and Hibberd, P.L. and Parsons, S.K.
DOI: 10.1097/00043426-200201000-00011British Journal of Haematology
Feldmann, J. and Le Deist, F. and Ouach{\'e}e-Chardin, M. and Certain, S. and Alexander, S. and Quartier, P. and Haddad, E. and Wulffraat, N. and Casanova, J.L. and Blanche, S. and Fischer, A. and De Saint Basile, G.
DOI: 10.1046/j.1365-2141.2002.03534.xAmerican Journal of Pediatric Hematology Oncology
Parsons, S.K. and Mayer, D.K. and Alexander, S.W. and Xu, R. and Land, V. and Laver, J.
DOI: 10.1097/00043426-200005000-00008Current Clinical Topics in Infectious Diseases
Alexander, S.W. and Pizzo, P.A.
The addition of blinatumomab, a type of immunotherapy, to conventional chemotherapy for children and adults with acute lymphoblastic leukemia (ALL) increases the chance of cure. A side effect of blinatumomab is decreasing healthy B cells. These cells are part of the immune system and are important in making immune globulin, which help protect individuals from infections. This research focuses on understanding the impacts of the addition on blinatumomab in children treated for ALL on risks of infection and strategies to minimize these risks, including immune globulin replacement.
Children and adolescents with mature B cell lymphoma (Burkittt lymphoma and diffuse large B cell lymphoma) have a high chance of being cured with combination immunochemotherapy. Current therapy comes with substantive risks of short term side effects and some risks of longer term side effects. This research focuses on identifying patients, based on clinical features and tumor biology, that can receive less intensive chemotherapy, with a goal of preserving excellent chance of cure but doing so with less toxicity.
Optimal therapy for children with various types of cancer now uses both conventional chemotherapy and immunotherapy. Little is known about the impacts of this treatment on protection from standard childhood vaccine preventable infections. This research will evaluate the impacts of cancer therapy on vaccine serologies and strategies for optimizing protection post completion of cancer therapy.
Every day, our researchers work towards breakthroughs to transform the lives of kids in BC and around the world. Learn about our latest innovations and advancements in child health.
February 15 was International Childhood Cancer Day and to mark the occasion we spoke with Dr. Sarah Alexander, a new BCCHR investigator and pediatric oncologist at BC Children’s Hospital who specializes in some of the most common childhood cancers, including non-Hodgkin lymphoma and acute lymphoblastic leukemia (ALL).
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