Tom Blydt-Hansen

MD

Investigator, BC Children's Hospital
Director, Pediatric Multi Organ Transplant Program, BC Children's Hospital

Kidney transplantation is a life-saving treatment for children with end-stage kidney failure. A major threat to success is rejection, where the body’s immune system attacks and destroys the transplanted kidney. If rejection isn't treated early, it results in permanent injury that can lead to loss of the transplant and a return to dialysis. Currently, tests that monitor kidney function will miss early or mild rejection. Instead, we screen with repeated kidney biopsies, which are risky and unpleasant.

This research program will use proven techniques to identify signs of kidney injury and rejection in the urine of children who have had a kidney transplant. It will focus on the first year after transplant, since this is the highest risk for rejection. We will look for metabolites and chemokines that we have tested before to identify when injury or rejection is present. Metabolites are small molecules produced by our cells as part of their function or as waste products. Chemokines are a different type of molecule that is produced by our immune system to signal inflammation. We already know some of the changes that occur with rejection. We now plan to validate that the same changes are present in other Canadian children with kidney transplants.

We will ask children with a new kidney transplant and their families to participate in this study. They will provide a urine sample for analysis whenever they have a kidney biopsy and also at regular intervals after transplant. We will verify the metabolite and chemokine levels that are linked to rejection, and could predict rejection in other children. Once it has been refined, we will determine whether it improves outcome by using it as a test for real-time monitoring and limit our use of regular kidney biopsies. We hope to demonstrate that this will improve the accuracy to detect rejection early, reduce the number of biopsies and improve the health and long-term kidney function of children with a transplant.

Academic Affiliations

  • Associate Professor, , Department of Pediatrics, Faculty of Medicine, University of British Columbia
  • Research Theme: Childhood Diseases
  • Research Group(s): Clinical and Community Data, Analytics and Informatics

Contact Information

Location

4480 Oak Street, Vancouver, British Columbia, Canada, V6H 3V4

Challenges in Small Sample Size Cluster Trials for Medication Adherence: Insights From TAKE-IT-TOO

Pediatric Transplantation

Spencer W. Riddell and Robert Platt and Mary Amanda Dew and Annette DeVito Dabbs and Vikas R. Dharnidharka and Brbel Knuper and Gillian Mayersohn and Chia Wei Teoh and Vronique Phan and Tom Blydt-Hansen and Jodi Smith and Bethany J. Foster

DOI: 10.1111/petr.70250

01 / 2026

Outcomes of Steroid Based Versus Steroid Minimizing Immunosuppression in Pediatric Kidney Transplant Recipients: A NAPRTCS Study

Pediatric Transplantation

Nicole Hayde and Eliza Blanchette and Margret Bock and Tom Blydt-Hansen

DOI: 10.1111/petr.70241

12 / 2025

Evaluating Activated Regulatory T Cells as a Biomarker of Chronic Allograft Inflammation in Pediatric Kidney Transplant Recipients

Pediatric Transplantation

Leung, M.L. and Barrett-Chan, E. and Levings, M.K. and Vercauteren, S. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.70041

Combination Automated Microfluidics Measurement of Urine C-C Motif Ligand 2, CXC-Motif Chemokine 9, CXC-Motif Chemokine 10, and Vascular Endothelial Growth Factor A for Monitoring Patients with a Kidney Transplant

Clinical Journal of the American Society of Nephrology

Seifert, M.E. and Kho, A.T. and Sheward, L. and Rodig, N. and Goldberg, S. and Diehl, M. and Zurakowski, D. and Mannon, R.B. and Dharnidharka, V.R. and Bestard, O. and Blydt-Hansen, T.D. and Briscoe, D.M.

DOI: 10.2215/CJN.0000000666

Perspectives on Conducting Behavioral Intervention With Adolescents Using a Virtual Platform"A Thematic Analysis From the Viewpoint of Study Coordinators

Pediatric Transplantation

Ghezzo, A. and Pascale, G. and Dew, M.A. and Rennick, J.E. and Dabbs, A.D. and Dharnidharka, V.R. and Kn{\"a}uper, B. and Mayersohn, G. and Teoh, C.W. and Phan, V. and Blydt-Hansen, T. and Smith, J. and Foster, B.J.

DOI: 10.1111/petr.70006

Evaluating family-centred care at BC Children's Hospital: Healthcare providers' perspectives

Journal of Evaluation in Clinical Practice

Kolar, T. and Cook, C.B. and Cooper, A. and Blydt-Hansen, T. and Connolly, M.B. and Boelman, C. and Chhina, H. and Datta, A. and Demos, M. and Hildebrand, K.J. and Selby, K. and Shen, Y. and Wenderfer, S.E. and Elliott, A.M.

DOI: 10.1111/jep.14187

HELP-KIDNEY: Health Literacy and Patient Outcomes in Pediatric Kidney Transplant

Pediatric Transplantation

Haubrich, K. and Broad, K. and Hind, T. and Blydt-Hansen, T.

DOI: 10.1111/petr.70012

Association of Dietary Micronutrient Intake and the Metabolome in Children with Chronic Kidney Disease

Clinical Journal of the American Society of Nephrology

Hasson, D.C. and Surapaneni, A. and Rebholz, C.M. and Greenberg, J.H. and Goncalves, M. and Ng, D.K. and Lee, A.M. and Furth, S.L. and Denburg, M.R. and Grams, M.E. and Fathallah-Shaykh, S. and Nayak, A. and Barletta, G.-M. and Blydt-Hansen, T. and Dionne, J. and Wong, C. and Yadin, O. and Ingulli, E. and Mak, R. and Sanchez-Kazi, C. and Moudgil, A. and Bhatnagar, S. and Abitbol, C. and DeFrietas, M. and Katsoufis, C. and Seeherunvong, W. and Greenbaum, L. and Harshman, L. and Verghese, P. and Krishnan, S. and Wilson, A. and Kiessling, S. and Murphy, M. and Shah, S. and Sullivan, J. and El-Dahr, S. and Drury, S. and Rodig, N. and Dart, A. and Atkinson, M. and Modi, Z. and Thomas, J. and Warady, B. and Johnson, R. and Dharnidharka, V. and Hooper, S. and Massengill, S. and Gomez-Mendez, L. and Hand, M. and Carlson, J. and Wong, C. and Kaskel, F. and Shinnar, S. and Saland, J. and Levy, R. and Lande, M. and Schwartz, G. and Mongia, A. and Claes, D. and Mitsnefes, M. and Dell, K.M. and Patel, H. and Yamaguchi, I. and Parekh, R. and Al-Uzri, A. and Richardson, K. and Copelovitch, L. and Hartung, E. and Ku, E. and Samuels, J. and Srivaths, P. and Becker, A. and Mohtat, D. and Norwood, V. and Flynn, J. and Halbach, S. and Sreedharan, R. and Bartosh, S.

DOI: 10.2215/CJN.0000000811

Anxiety and Depressive Symptoms Post-COVID-19 Pandemic Onset in Solid Organ Transplant Recipients: Canadian Repeated Cross-Sectional Study

Journal of Clinical Medicine

Fadlallah, J. and Shah, V. and Samudio, A. and Blydt-Hansen, T. and Mucsi, I.

DOI: 10.3390/jcm14144920

Perspectives on Accessing Mental Health Supports for Youth Living With Post-Traumatic Stress Symptoms After a Solid Organ Transplant

Pediatric Transplantation

Tam, M.T. and Riminchan, A. and Wu, J.M. and Wiedman, C. and Ho, M. and Li, L. and Blydt-Hansen, T. and Robillard, J.M.

DOI: 10.1111/petr.70170

Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease

Science Translational Medicine

Clotet-Freixas, S. and Zaslaver, O. and Kotlyar, M. and Pastrello, C. and Quaile, A.T. and McEvoy, C.M. and Saha, A.D. and Farkona, S. and Boshart, A. and Zorcic, K. and Neupane, S. and Manion, K. and Allen, M. and Chan, M. and Chen, X. and Arnold, A.P. and Sekula, P. and Steinbrenner, I. and Kttgen, A. and Dart, A.B. and Wicklow, B. and McGavock, J.M. and Blydt-Hansen, T.D. and Barrios, C. and Riera, M. and Soler, M.J. and Isenbrandt, A. and Lamontagne-Proulx, J. and Pradeloux, S. and Coulombe, K. and Soulet, D. and Rajasekar, S. and Zhang, B. and John, R. and Mehrotra, A. and Gehring, A. and Puhka, M. and Jurisica, I. and Woo, M. and Scholey, J.W. and Rst, H. and Konvalinka, A.

DOI: 10.1126/scitranslmed.abm2090

Vertebral Body Reshaping after Fractures: An Important Index of Recovery in Glucocorticoid-Treated Children

Journal of Clinical Endocrinology and Metabolism

Ma, J. and Siminoski, K. and Jaremko, J.L. and Koujok, K. and Matzinger, M.A. and Shenouda, N. and Wilson, N. and Cheng, M. and Alos, N. and Atkinson, S. and Cummings, E.A. and Ho, J. and Rodd, C. and Sbrocchi, A.M. and Stein, R. and Barr, R. and Cairney, E. and Dix, D.B. and Fernandez, C.V. and Grant, R. and Halton, J. and Israels, S. and Laverdire, C. and Lewis, V.A. and Cabral, D.A. and Huber, A. and Houghton, K. and Jurencak, R. and Lang, B. and LarchCrossed D Sign?, M. and Leblanc, C.M.A. and Miettunen, P. and Roth, J. and Scuccimarri, R. and Bell, L. and Blydt-Hansen, T. and Filler, G. and Feber, J. and Phan, V. and Smit, K. and Rauch, F. and Ward, L.M.

DOI: 10.1210/clinem/dgad611

Metabolomic identification of predictive and early biomarkers of cisplatin-induced acute kidney injury in adult head and neck cancer patients

British Journal of Clinical Pharmacology

Lim, Y.J. and Xiu, S.G. and Kuruvilla, M.S. and Winquist, E. and Welch, S. and Black, M. and Faught, L.N. and Lee, J. and Rieder, M.J. and Blydt-Hansen, T.D. and Zappitelli, M. and Urquhart, B.L.

DOI: 10.1111/bcp.15666

Exploring the ability of ChatGPT to create quality patient education resources about kidney transplant

Patient Education and Counseling

Tian Tran, J. and Burghall, A. and Blydt-Hansen, T. and Cammer, A. and Goldberg, A. and Hamiwka, L. and Johnson, C. and Kehler, C. and Phan, V. and Rosaasen, N. and Ruhl, M. and Strong, J. and Teoh, C.W. and Wichart, J. and Mansell, H.

DOI: 10.1016/j.pec.2024.108400

Detection of Subclinical Rejection in Pediatric Kidney Transplantation: Current and Future Practices

Pediatric Transplantation

Ettenger, R. and Seifert, M. and Blydt-Hansen, T. and Briscoe, D. and Holman, J. and Weng, P. and Srivastava, R. and Fleming, J. and Malekzadeh, M. and Pearl, M.

DOI: 10.1111/petr.14836

COVID-19 disease among children and young adults enrolled in the North American Pediatric Renal Trials and Collaborative Studies registry

Pediatric Nephrology

Twichell, S. and Ashoor, I. and Boynton, S. and Dharnidharka, V. and Kizilbash, S. and Erez, D.L. and Smith, J. and Somers, M. and Chua, A. and Hooper, D. and Barletta, G.-M. and Belsha, C. and Brakeman, P. and Verghese, P. and Atkinson, M. and Warady, B. and Bartosh, S. and Swinford, R. and Zahr, R. and Blydt-Hansen, T. and Haddad, M. and Lee-Son, K. and Harshman, L. and Benador, N. and DeFreitas, M. and Luckritz, K. and Fathallah-Shaykh, S. and Warejko, J. and Flynn, J. and Jetton, J. and Patel, H. and Czech, K. and Cramer, C. and Sharma, A. and Chen, A. and Bock, M. and Moudgil, A. and Milner, R. and Nelson, R. and Richardson, K. and Del Rio, M. and Sheth, R. and Kees-Folts, D. and Shah, S. and Dell, K. and Swartz, S. and Hunt, E. and Andreoli, S. and Nguyen, C. and Puliyanda, D. and Laskin, B. and Araya, C. and Sutherland, S. and Woroniecki, R. and Pinsk, M. and Rademacher, E. and Aviles, D. and Kamal, S. and Staples, A. and Lieberman, K. and Feber, J. and Al-Akash, S. and Ramirez, J. and McKenney, D. and Constantinescu, A. and Pena, D. and Steinke, J. and Cai, Y. and Thomas, J.

DOI: 10.1007/s00467-023-06241-0

Immune phenotyping in a pediatric multicenter transplant study: Suitability of a preformulated dry-antibody panel system

Human Immunology

Ionescu, L.I. and Blydt-Hansen, T. and Foster, B.J. and Allen, U. and Birk, P.E. and Hamiwka, L. and Phan, V. and Min, S. and Ivison, S. and Levings, M. and West, L.J. and Mital, S. and Urschel, S.

DOI: 10.1016/j.humimm.2024.110837

Risk Factors of Post-Traumatic Stress in Pediatric Solid Organ Transplant Recipients

Pediatric transplantation

Hind, T. and Robillard, J. and Armstrong, K. and Guttman, O. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.14854

Optimizing the approach to monitoring allograft inflammation using serial urinary CXCL10/creatinine testing in pediatric kidney transplant recipients

Pediatric Transplantation

Barrett-Chan, E. and Wang, L. and Bone, J. and Thachil, A. and Vytlingam, K. and Blydt-Hansen, T.

DOI: 10.1111/petr.14718

Developing Guidance for Donor Intervention Randomized Controlled Trials: Initial Discussions From the Canada-United Kingdom 2022 Workshop

Transplantation

Slessarev, M. and Bain, K.L. and Basmaji, J. and Blydt-Hansen, T.D. and Cooper, J. and D'Aragon, F. and Del Sorbo, L. and Evans, A. and Gordon, A.C. and Klein, G. and Meade, M.O. and Murphy, N. and Thomas, H.L. and Weiss, M.J. and Weijer, C. and Harvey, D.

DOI: 10.1097/TP.0000000000004983

Let's get physical: Aerobic capacity, muscle strength, and muscle endurance after pediatric heart transplantation

Pediatric Transplantation

Krysler, A.R. and Allan, C.J. and Larsen, I. and Mathur, S. and Morgan, C. and Greenway, S.C. and Blydt-Hansen, T. and Khoury, M. and West, L.J. and Urschel, S.

DOI: 10.1111/petr.14731

An Overview of Pre-Analytical Factors Impacting Metabolomics Analyses of Blood Samples

Metabolites

Thachil, A. and Wang, L. and Mandal, R. and Wishart, D. and Blydt-Hansen, T.

DOI: 10.3390/metabo14090474

An 8-Week Virtual Exercise Training Program for Pediatric Solid Organ Transplant Recipients

Pediatric Exercise Science

Grishin, N.K. and De Souza, A.M. and Fairbairn, J. and Sheel, A.W. and Puterman, E. and Blydt-Hansen, T. and Potts, J.E. and Armstrong, K.R.

DOI: 10.1123/pes.2023-0066

Adrenal insufficiency in pediatric kidney transplantation recipients

Pediatric Transplantation

Chae, H.H. and Ahmed, A. and Bone, J.N. and Abdulhussein, F.S. and Amed, S. and Patel, T. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.14768

Follow-up biopsies identify high rates of persistent rejection inpediatric kidney transplant recipients after treatment of T cell-mediated rejection

Pediatric Transplantation

Landsberg, A. and Raza, S.S. and Seifert, M.E. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.14617

Urinary TIMP-2*IGFBP-7 to diagnose acute kidney injury in children receiving cisplatin

Pediatric Nephrology

Chui, H. and McMahon, K.R. and Rassekh, S.R. and Schultz, K.R. and Blydt-Hansen, T.D. and Mammen, C. and Pinsk, M. and Cuvelier, G.D.E. and Carleton, B.C. and Tsuyuki, R.T. and Ross, C.J.D. and Devarajan, P. and Huynh, L. and Yordanova, M. and Crpeau-Hubert, F. and Wang, S. and Cockovski, V. and Palijan, A. and Zappitelli, M.

DOI: 10.1007/s00467-023-06007-8

Tubular Injury Biomarkers to Predict CKD and Hypertension at 3 Months Post-Cisplatin in Children

Kidney360

Huang, R.S. and Mcmahon, K.R. and Wang, S. and Chui, H. and Lebel, A. and Lee, J. and Cockovski, V. and Rassekh, S.R. and Schultz, K.R. and Blydt-Hansen, T.D. and Cuvelier, G.D.E. and Mammen, C. and Pinsk, M. and Carleton, B.C. and Tsuyuki, R.T. and Ross, C.J.D. and Palijan, A. and Zappitelli, M. and Baruchel, S. and Bouffet, E. and Blydt-Hansen, T. and Carleton, B.C. and Cuvelier, G.D.E. and Desai, S. and Devarajan, P. and Fernandez, C. and Fleming, A. and Gibson, P. and Laverdire, C. and Lewis, V. and Mammen, C. and Mcbride, M.L. and Michon, B. and Mitchell, L.G. and Pinsk, M. and Ramphal, R. and Rassekh, S.R. and Ross, C.J.D. and Sabapathy, C. and Schultz, K.R. and Tsuyuki, R.T. and Zappitelli, M. and Zorzi, A.

DOI: 10.34067/KID.0000000000000448

Exploring the Ethical Considerations of Direct Contact in Pediatric Organ Transplantation: A Qualitative Study

AJOB Empirical Bioethics

Jordan Joseph Wadden and Jordan Hermiston and Tom D. Blydt-Hansen and Ranjeet Dhaliwal and Shelby Gielen and Alice Virani

DOI: 10.1080/23294515.2022.2160513

07 / 2023

Noninvasive testing for mycophenolate exposure in children with renal transplant using urinary metabolomics

Pediatric Transplantation

Khalid Taha and Atul Sharma and Kristine Kroeker and Colin Ross and Bruce Carleton and David Wishart and Mara Medeiros and Tom D. Blydt-Hansen

DOI: 10.1111/petr.14460

05 / 2023

Differences in medication adherence by sex and organ type among adolescent and young adult solid organ transplant recipients

Pediatric Transplantation

Yulia Vaisbourd and Mourad Dahhou and Xun Zhang and Ruth Sapir-Pichhadze and Heloise Cardinal and Olwyn Johnston and Tom D. Blydt-Hansen and Lee Anne Tibbles and Lorraine Hamiwka and Simon Urschel and Patricia Birk and Janice Bissonnette and Mina Matsuda-Abedini and Jennifer Harrison BScPhm and Jeffrey Schiff and Veronique Phan and Sabina De Geest and Upton Allen and Yaron Avitzur and Seema Mital and Bethany J. Foster

DOI: 10.1111/petr.14446

03 / 2023

Acute kidney injury during cisplatin therapy and associations with kidney outcomes 2 to 6months post-cisplatin in children: a multi-centre, prospective observational study

Pediatric Nephrology

McMahon, K.R. and Lebel, A. and Rassekh, S.R. and Schultz, K.R. and Blydt-Hansen, T.D. and Cuvelier, G.D.E. and Mammen, C. and Pinsk, M. and Carleton, B.C. and Tsuyuki, R.T. and Ross, C.J.D. and Huynh, L. and Yordanova, M. and Crpeau-Hubert, F. and Wang, S. and Palijan, A. and Lee, J. and Boyko, D. and Zappitelli, M.

DOI: 10.1007/s00467-022-05745-5

Blood Pressure Classification Status in Children With CKD Following Adoption of the 2017 American Academy of Pediatrics Guideline

American Journal of Kidney Diseases

Ng, D.K. and Carroll, M.K. and Furth, S.L. and Warady, B.A. and Flynn, J.T. and Fathallah-Shaykh, S. and Nayak, A. and Turman, M. and Blydt-Hansen, T. and Wong, C. and Alexander, S. and Yadin, O. and Ingulli, E. and Mak, R. and Sanchez-Kazi, C. and Moudgil, A. and Gluck, C. and Abitbol, C. and DeFrietas, M. and Katsoufis, C. and Seeherunvong, W. and Greenbaum, L. and Harshman, L. and Langman, C. and Ann \& Robert, H. and Krishnan, S. and Wilson, A. and Kiessling, S. and Murphy, M. and Shah, S. and Sullivan, J. and Gupta, S. and El-Dahr, S. and Drury, S. and Rodig, N. and Dart, A. and Atkinson, M. and Gerson, A. and Matoo, T. and Modi, Z. and Quiroga, A. and Warady, B. and Johnson, R. and Dharnidharka, V. and Hooper, S. and Massengill, S. and Gomez-Mendez, L. and Hand, M. and Carlson, J. and Tawadrous, H. and Jodorkovsky, R. and Wong, C. and Kaskel, F. and Shinnar, S. and Saland, J. and Lande, M. and Schwartz, G. and Mongia, A. and Claes, D. and Mitsnefes, M. and Dell, K. and Patel, H. and Lane, P. and Parekh, R. and Al-Uzri, A. and Richardson, K. and Furth, S. and Copelovitch, L. and Ku, E. and Samuels, J. and Srivaths, P. and Al-Akash, S. and Seo-Mayer, P. and Norwood, V. and Flynn, J. and Pan, C. and Bartosh, S.

DOI: 10.1053/j.ajkd.2022.10.009

Vitamin D Toxicity from an Unusual and Unexpected Source: A Report of 2 Cases

Hormone Research in Paediatrics

Silva, C. and Fung, A.W.S. and Masson, V. and Assen, K. and Ward, V. and McKenzie, J. and Blydt-Hansen, T.D. and Cosme, J. and Van Der Gugten, G. and Barakauskas, V.E. and Fox, D.A.

DOI: 10.1159/000526755

Parent and healthcare provider views of live varicella vaccination of pediatric solid organ transplant recipients

Pediatric Transplantation

Condran, B. and Kervin, M. and Burton, C. and Blydt-Hansen, T.D. and Morris, S.K. and Sadarangani, M. and Otley, A. and Yong, E. and Mitchell, H. and Bettinger, J.A. and Top, K.A.

DOI: 10.1111/petr.14609

International Pediatric Transplant Association (IPTA) position statement supporting prioritizing pediatric recipients for deceased donor organ allocation

Pediatric Transplantation

Freeman, M.A. and Botha, J. and Brewer, E. and Damian, M. and Ettenger, R. and Gambetta, K. and Lefkowitz, D.S. and Ross, L. and Superina, R. and McCulloch, M. and Blydt-Hansen, T.

DOI: 10.1111/petr.14358

Development of an adaptive clinical web-based prediction tool for kidney replacement therapy in children with chronic kidney disease

Kidney International

Ng, D.K. and Matheson, M.B. and Schwartz, G.J. and Wang, F.M. and Mendley, S.R. and Furth, S.L. and Warady, B.A. and Fathallah-Shaykh, S. and Nayak, A. and Turman, M. and Blydt-Hansen, T. and Wong, C. and Alexander, S. and Yadin, O. and Ingulli, E. and Mak, R. and Sanchez-Kazi, C. and Moudgil, A. and Muneeruddin, S. and Abitbol, C. and DeFrietas, M. and Katsoufis, C. and Seeherunvong, W. and Greenbaum, L. and Harshman, L. and Verghese, P. and Krishnan, S. and Wilson, A. and Kiessling, S. and Murphy, M. and Shah, S. and Sullivan, J. and Gupta, S. and El-Dahr, S. and Drury, S. and Rodig, N. and Dart, A. and Atkinson, M. and Gerson, A. and Matoo, T. and Modi, Z. and Thomas, J. and Warady, B. and Johnson, R. and Dharnidharka, V. and Hooper, S. and Massengill, S. and Gomez-Mendez, L. and Hand, M. and Carlson, J. and Wong, C. and Kaskel, F. and Shinnar, S. and Saland, J. and Lande, M. and Schwartz, G. and Mongia, A. and Claes, D. and Mitsnefes, M. and Dell, K. and Patel, H. and Lane, P. and Parekh, R. and Robinson, L. and Al-Uzri, A. and Richardson, K. and Furth, S. and Copelovitch, L. and Ku, E. and Samuels, J. and Srivaths, P. and Al-Akash, S. and Mohtat, D. and Norwood, V. and Flynn, J. and Pan, C. and Bartosh, S.

DOI: 10.1016/j.kint.2023.06.020

Perspectives of Pediatric Nephrologists, Intensivists and Nurses Regarding AKI Management and Expected Outcomes

Canadian Journal of Kidney Health and Disease

Che, A. and D?Arienzo, D. and Dart, A. and Mammen, C. and Samuel, S. and Alexander, T. and Morgan, C. and Blydt-Hansen, T. and Fontela, P. and Guerra, G.G. and Chanchlani, R. and Wang, S. and Cockovski, V. and Jawa, N. and Lee, J. and Nunes, S. and Reynaud, S. and Zappitelli, M.

DOI: 10.1177/20543581231168088

The collection of evidence-based data on exercise in the case of solid organ transplantation: How far have we progressed?,La collecte de donnes probantes sur lexercice en cas de transplantation dorgane plein: quel point avons-nous progress?

Physiotherapy Canada

Mathur, S. and Janaudis-Ferreira, T. and Ferreira, M.P. and Bourgeois, N. and Blydt-Hansen, T. and Fuller, T. and Deliva, R. and Hamiwka, L.

DOI: 10.3138/ptc-2022-0111-fr

Child and caregiver perspectives on access to psychosocial and educational support in pediatric chronic kidney disease: a focus group study

Pediatric Nephrology

Zhang, Y. and Gutman, T. and Tong, A. and Craig, J.C. and Sinha, A. and Dart, A. and Eddy, A.A. and Gipson, D.S. and Bockenhauer, D. and Yap, H.-K. and Groothoff, J. and Zappitelli, M. and J.A.Webb, N. and Alexander, S.I. and Furth, S. and Samuel, S. and Blydt-Hansen, T.D. and Dionne, J. and Michael, M. and Wenderfer, S.E. and Winkelmayer, W.C. and McTaggart, S. and Walker, A. and Zimmerman, C.T. and Ralph, A.F. and Ju, A. and James, L.J. and Hanson, C.S.

DOI: 10.1007/s00467-022-05551-z

Building the Evidence for Exercise in Solid Organ Transplant: How Far Have We Moved the Needle?

Physiotherapy Canada

Mathur, S. and Janaudis-Ferreira, T. and Ferreira, M.P. and Bourgeois, N. and Blydt-Hansen, T. and Fuller, T. and Deliva, R. and Hamiwka, L.

DOI: 10.3138/ptc-2022-0111

Revisiting the Application of an Adult Kidney Failure Risk Prediction Equation to Children With CKD

American Journal of Kidney Diseases

Menon, G. and Pierce, C.B. and Ng, D.K. and Fathallah-Shaykh, S. and Nayak, A. and Turman, M. and Blydt-Hansen, T. and Wong, C. and Alexander, S. and Yadin, O. and Ingulli, E. and Mak, R. and Sanchez-Kazi, C. and Moudgil, A. and Muneeruddin, S. and Abitbol, C. and DeFrietas, M. and Katsoufis, C. and Seeherunvong, W. and Greenbaum, L. and Harshman, L. and Verghese, P. and Krishnan, S. and Wilson, A. and Kiessling, S. and Shah, S. and Sullivan, J. and Gupta, S. and El-Dahr, S. and Drury, S. and Rodig, N. and Dart, A. and Atkinson, M. and Gerson, A. and Matoo, T. and Modi, Z. and Thomas, J. and Warady, B. and Johnson, R. and Dharnidharka, V. and Hooper, S. and Massengill, S. and Gomez-Mendez, L. and Hand, M. and Carlson, J. and Wong, C. and Kaskel, F. and Shinnar, S. and Saland, J. and Lande, M. and Schwartz, G. and Mongia, A. and Claes, D. and Mitsnefes, M. and Dell, K. and Patel, H. and Lane, P. and Parekh, R. and Robinson, L. and Al-Uzri, A. and Richardson, K. and Furth, S. and Copelovitch, L. and Ku, E. and Samuels, J. and Srivaths, P. and Al-Akash, S. and Mohtat, D. and Norwood, V. and Flynn, J. and Pan, C. and Bartosh, S.

DOI: 10.1053/j.ajkd.2022.11.004

High urinary CXCL10/Cr with onset of Burkitt lymphoma in a pediatric kidney transplant recipient

Pediatric Transplantation

Shwetha Suresh and David Dix and Li Wang and Tom D. Blydt-Hansen

DOI: 10.1111/petr.14354

11 / 2022

Clinical indicators of slow graft function and outcome after pediatric kidney transplantation

Pediatric Transplantation

Sargun Bajaj and Sharon Gershony and Kourosh Afshar and Tom David Blydt-Hansen

DOI: 10.1111/petr.14353

11 / 2022

The mental health profiles of pediatric organ transplant recipients

Pediatric Transplantation

Erika K. Penner and Hope Walker and Erin Moon and Janine Slavec and Tatsuma Hind and Tom D. Blydt-Hansen

DOI: 10.1111/petr.14151

02 / 2022

Height-adjusted lean body mass and its associations with physical activity and kidney function in pediatric kidney transplantation

Pediatric Transplantation

Azim Ahmed and Anita Cote and Samantha Lui and Tom D. Blydt-Hansen

DOI: 10.1111/petr.14128

02 / 2022

Catecholamines in neuroblastoma: Driver of hypertension, or solely a marker of disease?

Cancer Reports

Harding, M. and Deyell, R.J. and Blydt-Hansen, T.

DOI: 10.1002/cnr2.1569

Urinary metabolomics to develop predictors for pediatric acute kidney injury

Pediatric Nephrology

Franiek, A. and Sharma, A. and Cockovski, V. and Wishart, D.S. and Zappitelli, M. and Blydt-Hansen, T.D.

DOI: 10.1007/s00467-021-05380-6

Urine Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 to Detect Pediatric Cisplatin-Associated Acute Kidney Injury

Kidney360

Mcmahon, K.R. and Chui, H. and Rassekh, S.R. and Schultz, K.R. and Blydt-Hansen, T.D. and Mammen, C. and Pinsk, M. and Cuvelier, G.D.E. and Carleton, B.C. and Tsuyuki, R.T. and Ross, C.J.D. and Devarajan, P. and Huynh, L. and Yordanova, M. and Crpeau-Hubert, F. and Wang, S. and Cockovski, V. and Palijan, A. and Zappitelli, M.

DOI: 10.34067/KID.0004802021

Self-reported Race, Serum Creatinine, Cystatin C, and GFR in Children and Young Adults With Pediatric Kidney Diseases: A Report From the Chronic Kidney Disease in Children (CKiD) Study

American Journal of Kidney Diseases

Ng, D.K. and Furth, S.L. and Warady, B.A. and Crews, D.C. and Seegmiller, J.C. and Schwartz, G.J. and Fathallah-Shaykh, S. and Nayak, A. and Turman, M. and Blydt-Hansen, T. and Wong, C. and Alexander, S. and Yadin, O. and Ingulli, E. and Mak, R. and Sanchez-Kazi, C. and Moudgil, A. and Gluck, C. and Abitbol, C. and DeFrietas, M. and Katsoufis, C. and Seeherunvong, W. and Greenbaum, L. and Harshman, L. and Langman, C. and Krishnan, S. and Wilson, A. and Kiessling, S. and Murphy, M. and Shah, S. and Sullivan, J. and Gupta, S. and El-Dahr, S. and Drury, S. and Rodig, N. and Dart, A. and Atkinson, M. and Gerson, A. and Matoo, T. and Modi, Z. and Quiroga, A. and Warady, B. and Johnson, R. and Dharnidharka, V. and Hooper, S. and Massengill, S. and Gomez-Mendez, L. and Hand, M. and Carlson, J. and Tawadrous, H. and Jodorkovsky, R. and Wong, C. and Kaskel, F. and Shinnar, S. and Saland, J. and Lande, M. and Schwartz, G. and Mongia, A. and Claes, D. and Mitsnefes, M. and Dell, K. and Patel, H. and Lane, P. and Parekh, R. and Al-Uzri, A. and Richardson, K. and Furth, S. and Copelovitch, L. and Ku, E. and Samuels, J. and Srivaths, P. and Al-Akash, S. and Seo-Mayer, P. and Norwood, V. and Flynn, J. and Pan, C. and Bartosh, S.

DOI: 10.1053/j.ajkd.2021.10.013

An Integrated Clinical and Genetic Prediction Model for Tacrolimus Levels in Pediatric Solid Organ Transplant Recipients

Transplantation

Min, S. and Papaz, T. and Lambert, A.N. and Allen, U. and Birk, P. and Blydt-Hansen, T. and Foster, B.J. and Grasemann, H. and Hamiwka, L. and Litalien, C. and Ng, V. and Berka, N. and Campbell, P. and Daniel, C. and Saw, C.L. and Tinckam, K. and Urschel, S. and Van Driest, S.L. and Parekh, R. and Mital, S.

DOI: 10.1097/TP.0000000000003700

A review of ferric citrate clinical studies, and the rationale and design of the Ferric Citrate and Chronic Kidney Disease in Children (FIT4KiD) trial

Pediatric Nephrology

Hanudel, M.R. and Laster, M.L. and Portale, A.A. and Dokras, A. and Quigley, R.P. and Guzman, G.A.L. and Zaritsky, J.J. and Hayde, N.A. and Kaskel, F.J. and Mitsnefes, M.M. and Ramirez, J.A. and Imani, P.D. and Srivaths, P.R. and Kogon, A.J. and Denburg, M.R. and Blydt-Hansen, T.D. and Reyes, L.Z. and Greenbaum, L.A. and Weidemann, D.K. and Warady, B.A. and Elashoff, D.A. and Mendley, S.R. and Isakova, T. and Salusky, I.B.

DOI: 10.1007/s00467-022-05492-7

The impact of methodological choices when developing predictive models using urinary metabolite data

Statistics in Medicine

Krstic, N. and Multani, K. and Wishart, D.S. and Blydt-Hansen, T. and Cohen Freue, G.V.

DOI: 10.1002/sim.9431

A text messaging intervention and quality of life in adolescents with solid organ transplants

Pediatric Transplantation

Rathgeber, S.L. and Hutchison, S.M. and De Souza, A.-M. and Lester, R. and Blydt-Hansen, T. and Human, D.G. and Guttman, O. and Oberlander, T. and Armstrong, K.R.

DOI: 10.1111/petr.14219

Long-term respiratory outcomes following solid organ transplantation in children: A retrospective cohort study

Pediatric Pulmonology

Wright, M.F.A. and Blydt-Hansen, T. and Chilvers, M.A.

DOI: 10.1002/ppul.25968

Care processes and structures associated with higher medication adherence in adolescent and young adult transplant recipients

Pediatric Transplantation

Anita Dabirzadeh and Mourad Dahhou and Xun Zhang and Ruth Sapir-Pichhadze and Heloise Cardinal and Michel White and Olwyn Johnston and Tom D. Blydt-Hansen and Lee Anne Tibbles and Lorraine Hamiwka and Simon Urschel and Patricia Birk and Janice Bissonnette and Mina Matsuda-Abedini and Jennifer Harrison and Jeffrey Schiff and Veronique Phan and Sabina De Geest and Upton Allen and Seema Mital and Bethany J. Foster

DOI: 10.1111/petr.14106

12 / 2021

Self-reported physical activity and lack of association with health-related quality of life in a pediatric solid-organ transplant population

Pediatric Transplantation

Samantha Lui and Tatsuma Hind and Erin Moon and Astrid de Souza and Katherine Broad and Julie Fairbairn and Richard Schreiber and Kathryn Armstrong and Tom D. Blydt-Hansen

DOI: 10.1111/petr.14093

12 / 2021

Post-traumatic stress as a determinant of quality of life in pediatric solid-organ transplant recipients

Pediatric Transplantation

Tatsuma Hind and Samantha Lui and Erin Moon and Katherine Broad and Samantha Lang and Richard A. Schreiber and Kathryn Armstrong and Tom D. Blydt-Hansen

DOI: 10.1111/petr.14005

06 / 2021

The effects of exercise training in adult solid organ transplant recipients: A systematic review and meta-analysis

Transplant International

Tania Janaudis-Ferreira and Catherine M. Tansey and Sunita Mathur and Tom Blydt-Hansen and Julie Lamoureaux and Agns Rkel and Nathalia Parente de Sousa Maia and Andr Bussires and Sara Ahmed and Jill Boruff

DOI: 10.1111/tri.13848

05 / 2021

Patient-reported outcome measures in pediatric solid organ transplantation: Exploring stakeholder perspectives on clinical implementation through qualitative description.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Anthony SJ and Young K and Pol SJ and Selkirk EK and Blydt-Hansen T and Boucher S and Goldberg A and Hamiwka L and Haverman L and Mitchell J and Urschel S and Santana M and Stinson J and West LJ

DOI: 10.1007/s11136-020-02743-8 PubMed: 33447959

01 / 2021

Design and Methods of the Validating Injury to the Renal Transplant Using Urinary Signatures (VIRTUUS) Study in Children

Transplantation Direct

Kumar, J. and Contrepois, K. and Snyder, M. and Grimm, P.C. and Moudgil, A. and Smith, J.M. and Bobrowski, A.E. and Verghese, P.S. and Hooper, D. and Ingulli, E. and Lestz, R. and Weng, P. and Reason, J.L. and Blydt-Hansen, T.D. and Suthanthiran, M. and Keating, B. and Amaral, S.

DOI: 10.1097/TXD.0000000000001244

A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol

Canadian Journal of Kidney Health and Disease

Jain, A. and Huang, R. and Lee, J. and Jawa, N. and Lim, Y.J. and Guron, M. and Abish, S. and Boutros, P.C. and Brudno, M. and Carleton, B. and Cuvelier, G.D.E. and Gunaratnam, L. and Ho, C. and Adeli, K. and Kuruvilla, S. and Lajoie, G. and Liu, G. and Nathan, P.C. and Rod Rassekh, S. and Rieder, M. and Waikar, S.S. and Welch, S.A. and Weir, M.A. and Winquist, E. and Wishart, D.S. and Zorzi, A.P. and Blydt-Hansen, T. and Zappitelli, M. and Urquhart, B.

DOI: 10.1177/20543581211057708

High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

Communications Biology

Tran, J.N. and Gnther, O.P. and Sherwood, K.R. and Fenninger, F. and Allan, L.L. and Lan, J. and Sapir-Pichhadze, R. and Duquesnoy, R. and Claas, F. and Marsh, S.G.E. and McMaster, W.R. and Keown, P.A. and Bryan, S. and Caulfield, T. and Ragoussis, I. and Oualkacha, K. and Tinckam, K. and Liwski, R. and Campbell, P. and Cardinal, H. and De Serres, S.A. and Saw, C.L. and Mengel, M. and Sis, B. and Wagner, E. and Berka, N. and McManus, B. and Hebert, M.-J. and Foster, L.J. and Rossi, F. and Borchers, C.H. and Piccirillo, C.A. and Polychronakos, C. and Ng, R. and Jevnikar, A. and Cullis, P. and Filler, G. and Wong, H. and Foster, B. and Gill, J. and Kim, S.J. and Tibbles, L.A. and Humar, A. and Shechter, S. and Chaudhury, P. and Fernandez, N. and Fowler, E. and Kiberd, B. and Gill, J. and Fortin, M.-C. and Klarenbach, S. and Balshaw, R. and Mital, S. and Mucsi, I. and Ostrow, D. and Stiller, C. and Parekh, R.S. and Richard, L. and Senecal, L. and Blydt-Hansen, T. and Erlich, H. and Gebel, H. and Weimer, E. and Kaplan, B. and Burckart, G. and Middleton, D. and Marsh, S.G.E. and Tilanus, M. and van Gelder, T. and Opelz, G. and Oellerich, M. and Marquet, P. and Marra, C. and Kal, Z.

DOI: 10.1038/s42003-021-01989-3

Cell sex and sex hormones modulate kidney glucose and glutamine metabolism in health and diabetes

bioRxiv

Clotet-Freixas, S. and Zaslaver, O. and Pastrello, C. and Kotlyar, M. and McEvoy, C. and Farkona, S. and Saha, A. and Boshart, A. and Chan, M. and Riera, M. and Soler, M.J. and Isenbrandt, A. and Lamontagne-Proulx, J. and Pradeloux, S. and Coulombe, K. and Soulet, D. and Dart, A.B. and Wicklow, B. and McGavock, J.M. and Blydt-Hansen, T.D. and Jurisica, I. and Woo, M. and Scholey, J.W. and Rst, H. and Konvalinka, A.

DOI: 10.1101/2021.08.23.457385

Association of Urine Platinum With Acute Kidney Injury in Children Treated With Cisplatin for Cancer

Journal of Clinical Pharmacology

Lebel, A. and Chui, H. and McMahon, K.R. and Lim, Y.J. and Macri, J. and Wang, S. and Devarajan, P. and Blydt-Hansen, T.D. and Zappitelli, M. and Urquhart, B.L.

DOI: 10.1002/jcph.1839

Risk Factors for Developing Posttransplant Diabetes After Pediatric Kidney Transplant in a Canadian Tertiary Care Children's Hospital Between 1995 and 2016

Canadian Journal of Diabetes

Acosta-Gualandri, A. and Blydt-Hansen, T. and Islam, N. and Amed, S.

DOI: 10.1016/j.jcjd.2021.05.004

Rejection Challenges: Diagnosis and Management

Challenges in Pediatric Kidney Transplantation A Practical Guide

Lang, S. and Riazy, M. and Blydt-Hansen, T.D.

DOI: 10.1007/978-3-030-74783-1_3

The Accuracy of Incident Vertebral Fracture Detection in Children Using Targeted Case-Finding Approaches

Journal of Bone and Mineral Research

Ma, J. and Siminoski, K. and Wang, P. and Jaremko, J.L. and Koujok, K. and Matzinger, M.A. and Shenouda, N. and Lentle, B. and Alos, N. and Cummings, E.A. and Ho, J. and Houghton, K. and Miettunen, P.M. and Scuccimarri, R. and Rauch, F. and Ward, L.M. and Ward, L.M. and Konji, V. and Scharke, M. and Sykes, E. and Ho, J. and Kloiber, R. and Lewis, V. and Midgley, J. and Miettunen, P. and Stephure, D. and Lentle, B.C. and Blydt-Hansen, T. and Cabral, D. and Dix, D.B. and Houghton, K. and Nadel, H.R. and Hay, J. and Feber, J. and Halton, J. and Jurencak, R. and Koujok, K. and Matzinger, M. and Roth, J. and Shenouda, N. and Watanabe-Duffy, K. and Cairney, E. and Clarson, C. and Filler, G. and Grimmer, J. and McKillop, S. and Sparrow, K. and Stein, R. and Cummings, E. and Fernandez, C. and Huber, A.M. and Lang, B. and O'Brien, K. and Abish, S. and Bell, L. and LeBlanc, C. and Sbrocchi, A. and Scuccimarri, R. and Moher, D. and Taljaard, M. and Rauch, F. and Alos, N. and Dubois, J. and Laverdiere, C. and Phan, V. and Saint-Cyr, C. and Barsalou, J. and Couch, R. and Ellsworth, J. and Jaremko, J. and Siminoski, K. and Wilson, B. and Grant, R. and Charron, M. and Hebert, D. and Gaboury, I. and Taback, S. and Israels, S. and Oen, K. and Pinsk, M. and Reed, M. and Rodd, C.

DOI: 10.1002/jbmr.4294

Isolated diastolic high blood pressure: a distinct clinical phenotype in US children

Pediatric Research

Alsaeed, H. and Metzger, D.L. and Blydt-Hansen, T.D. and Rodd, C. and Sharma, A.

DOI: 10.1038/s41390-021-01369-x

Late first acute rejection in pediatric kidney transplantation: A North American Pediatric Renal Trials and Collaborative Studies special study.

Pediatric transplantation

Barton KT and Halani K and Galbiati S and Dandamudi R and Hmiel SP and Dharnidharka VR and NAPRTCS investigators

DOI: 10.1111/petr.13953 PubMed: 33350558

12 / 2020

Age and sex determine conversion from immediate-release to extended-release tacrolimus in a multi-center cohort of Canadian pediatric renal transplant recipients.

Pediatric transplantation

Lang S and Sharma A and Foster B and Gibson IW and Ho J and Nickerson P and Wishart D and Blydt-Hansen T

DOI: 10.1111/petr.13959 PubMed: 33368914

12 / 2020

Biomarker implementation: Evaluation of the decision-making impact of CXCL10 testing in a pediatric cohort.

Pediatric transplantation

Lamarche C and Sharma AK and Goldberg A and Wang L and Blydt-Hansen TD

DOI: 10.1111/petr.13908 PubMed: 33155737

11 / 2020

Management of Pediatric Kidney Transplant Patients During the COVID-19 Pandemic: Guidance From the Canadian Society of Transplantation Pediatric Group.

Canadian journal of kidney health and disease

Teoh CW and Gaudreault-Tremblay MM and Blydt-Hansen TD and Goldberg A and Arora S and Feber J and Langlois V and Ruhl M and Phan V and Morgan C and Acott P and Hamiwka L

DOI: 10.1177/2054358120967845 PubMed: 33240516

11 / 2020

Multicenter data to improve health for pediatric renal transplant recipients in North America: Complementary approaches of NAPRTCS and IROC.

Pediatric transplantation

Hooper DK and Misurac J and Blydt-Hansen T and Chua AN

DOI: 10.1111/petr.13891 PubMed: 33142362

11 / 2020

Investigating oxythiamine levels in children undergoing kidney transplantation and the risk of immediate post-operative metabolic and hemodynamic decompensation.

Pediatric nephrology (Berlin, Germany)

Golan O and Dyer R and Sinclair G and Blydt-Hansen T

DOI: 10.1007/s00467-020-04797-9 PubMed: 33067673

10 / 2020

Validity and utility of urinary CXCL10/Cr immune monitoring in pediatric kidney transplant recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Blydt-Hansen TD and Sharma A and Gibson IW and Wiebe C and Sharma AP and Langlois V and Teoh CW and Rush D and Nickerson P and Wishart D and Ho J

DOI: 10.1111/ajt.16336 PubMed: 33034126

10 / 2020

Yield and utility of surveillance kidney biopsies in pediatric kidney transplant recipients at various time points post-transplant.

Pediatric transplantation

Landsberg A and Riazy M and Blydt-Hansen TD

DOI: 10.1111/petr.13869 PubMed: 33073499

10 / 2020

Long-Term Outcomes of C3 Glomerulopathy and Immune-Complex Membranoproliferative Glomerulonephritis in Children.

Kidney international reports

Kirpalani A and Jawa N and Smoyer WE and Licht C and Midwest Pediatric Nephrology Consortium

DOI: 10.1016/j.ekir.2020.09.019 PubMed: 33305125

10 / 2020

Early surveillance biopsy utilization and management of pediatric renal allograft acute T cell-mediated rejection in Canadian centers: Observations from the PROBE multicenter cohort study.

Pediatric transplantation

Hoffmann AJ and Gibson IW and Ho J and Nickerson P and Rush D and Sharma A and Wishart D and Blydt-Hansen TD

DOI: 10.1111/petr.13870 PubMed: 33026135

10 / 2020

Low renal transplantation rates in children with end-stage kidney disease: A study of barriers in a low-resource setting.

Pediatric transplantation

Pais P and Blydt-Hansen TD and Michael Raj JA and Dello Strologo L and Iyengar A

DOI: 10.1111/petr.13867 PubMed: 33058452

10 / 2020

Adolescents with solid organ transplant: Using the BRIEF2 parent-report and self-report to measure parent-child agreement and everyday executive function.

Applied neuropsychology. Child

Hutchison SM and Rathgeber SL and De Souza AM and Blydt-Hansen T and Msse LC and Armstrong KR and Oberlander TF

DOI: 10.1080/21622965.2020.1800468 PubMed: 32758025

08 / 2020

An evaluation of renin-angiotensin system markers in youth with type 2 diabetes and associations with renal outcomes.

Pediatric diabetes

Dart AB and Wicklow B and Scholey J and Sellers EA and Dyck J and Mahmud F and Sochett E and Hamilton J and Blydt-Hansen T and Burns K

DOI: 10.1111/pedi.13081 PubMed: 32657529

07 / 2020

A Canadian Survey on Adverse Symptoms Experienced by Solid Organ Transplant Recipients.

Progress in transplantation (Aliso Viejo, Calif.)

Aladwan S and Harrison JJ and Blackburn DF and Taylor J and Blydt-Hansen TD and Mansell H

DOI: 10.1177/1526924820933821 PubMed: 32597328

06 / 2020

Improving the Care for Pediatric Transplant Patients through Integration of Patient-Reported Outcome Measures into Clinical Practice

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Anthony, S.J. and Young, K. and Pol, S.J. and Blydt-Hansen, T. and Goldberg, A. and Hamiwka, L. and Urschel, S. and Santana, M. and Stinson, J. and West, L.J.

DOI: 10.1016/j.healun.2020.01.1201

Epidemiologic Characteristics of Acute Kidney Injury during Cisplatin Infusions in Children Treated for Cancer

JAMA Network Open

McMahon, K.R. and Rassekh, S.R. and Schultz, K.R. and Blydt-Hansen, T. and Cuvelier, G.D.E. and Mammen, C. and Pinsk, M. and Carleton, B.C. and Tsuyuki, R.T. and Ross, C.J.D. and Palijan, A. and Huynh, L. and Yordanova, M. and Crpeau-Hubert, F. and Wang, S. and Boyko, D. and Zappitelli, M.

DOI: 10.1001/jamanetworkopen.2020.3639

Becoming unique: A qualitative study of identity development of adolescent kidney recipients

Pediatric Transplantation

Leblond, M. and Achille, M. and Clermont, M.-J. and Blydt-Hansen, T.

DOI: 10.1111/petr.13607

Disseminating Knowledge to Providers on Exercise Training After Solid Organ Transplantation

Progress in Transplantation

Janaudis-Ferreira, T. and Mathur, S. and Tansey, C.M. and Blydt-Hansen, T. and Hartell, D.

DOI: 10.1177/1526924820913506

Valganciclovir prophylaxis delays onset of EBV viremia in high-risk pediatric solid organ transplant recipients

Pediatric Research

Albatati, S. and Sharma, A. and Haubrich, K. and Wright, A. and Gantt, S. and Blydt-Hansen, T.D.

DOI: 10.1038/s41390-019-0523-4

Physical activity and its correlates in a pediatric solid-organ transplant population

Pediatric Transplantation

Lui, S. and de Souza, A. and Sharma, A. and Fairbairn, J. and Schreiber, R. and Armstrong, K. and Blydt-Hansen, T.

DOI: 10.1111/petr.13745

Using Text Messaging to Communicate with Adolescent Heart Transplant Patients

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Rathgeber, S.L. and Hutchison, S. and De Souza, A.M. and Timothy, O. and Galvin, C.R. and Potts, J. and Human, D. and Blydt-Hansen, T. and Lester, R. and Armstrong, K.R.

DOI: 10.1016/j.healun.2020.01.305

Evidence for the alloimmune basis and prognostic significance of Borderline T cell"mediated rejection

American Journal of Transplantation

Wiebe, C. and Rush, D.N. and Gibson, I.W. and Pochinco, D. and Birk, P.E. and Goldberg, A. and Blydt-Hansen, T. and Karpinski, M. and Shaw, J. and Ho, J. and Nickerson, P.W.

DOI: 10.1111/ajt.15860

A Holistic Approach to Risk for Early Kidney Injury in Indigenous Youth With Type 2 Diabetes: A Proof of Concept Paper From the iCARE Cohort

Canadian Journal of Kidney Health and Disease

Dart, A.B. and Wicklow, B. and Blydt-Hansen, T.D. and Sellers, E.A.C. and Malik, S. and Chateau, D. and Sharma, A. and McGavock, J.M.

DOI: 10.1177/2054358119838836

Erratum: Pediatric outcomes in transplant: Personalising immunosuppression to improve efficacy (positive study): the collaboration and design of a national transplant precision medicine program (Transplantation Direct (2018) 4 (e410) DOI: 10.1097/TXD.0000000000000842)

Transplantation Direct

Papaz, T. and Allen, U. and Blydt-Hansen, T. and Birk, P.E. and Min, S. and De Geest, S. and Hamiwka, L. and Phan, V. and Schechter, T. and Wall, D.A. and Urschel, S. and Foster, B.J. and Mital, S.

DOI: 10.1097/TXD.0000000000000864

To accompany Banas et al., Time for a Paradigm Shift

EBioMedicine

Sharma, A.K. and Blydt-Hansen, T.D.

DOI: 10.1016/j.ebiom.2019.10.042

Kidney transplant practice patterns and outcome benchmarks over 30years: The 2018 report of the NAPRTCS

Pediatric Transplantation

Chua, A. and Cramer, C. and Moudgil, A. and Martz, K. and Smith, J. and Blydt-Hansen, T. and Neu, A. and Dharnidharka, V.R.

DOI: 10.1111/petr.13597

Estimating glomerular filtration rate in youth with obesity and type 2 diabetes: the iCARE study equation

Pediatric Nephrology

Dart, A.B. and McGavock, J. and Sharma, A. and Chateau, D. and Schwartz, G.J. and Blydt-Hansen, T.

DOI: 10.1007/s00467-019-04250-6

Resolution of diagnosis and parental attitudes among parents of adolescent kidney recipients

Pediatric Transplantation

Leblond, M. and Achille, M. and Bliveau, M.-J. and Clermont, M.-J. and Blydt-Hansen, T.

DOI: 10.1111/petr.13472

Acute Shoshin beriberi syndrome immediately post"kidney transplant with rapid recovery after thiamine administration

Pediatric Transplantation

Elias, I.M. and Sinclair, G. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.13493

Risk factors associated with allograft failure in pediatric kidney transplant recipients with focal segmental glomerulosclerosis

Pediatric Transplantation

Koh, L.J. and Martz, K. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.13469

Identifying Important Outcomes for Young People With CKD and Their Caregivers: A Nominal Group Technique Study

American Journal of Kidney Diseases

Hanson, C.S. and Gutman, T. and Craig, J.C. and Bernays, S. and Raman, G. and Zhang, Y. and James, L.J. and Ralph, A.F. and Ju, A. and Manera, K.E. and Teixeira-Pinto, A. and Viecelli, A.K. and Alexander, S.I. and Blydt-Hansen, T.D. and Dionne, J. and McTaggart, S. and Michael, M. and Walker, A. and Carter, S. and Wenderfer, S.E. and Winkelmayer, W.C. and Bockenhauer, D. and Dart, A. and Eddy, A.A. and Furth, S.L. and Gipson, D.S. and Goldstein, S.L. and Groothoff, J. and Samuel, S. and Sinha, A. and Webb, N.J.A. and Yap, H.-K. and Zappitelli, M. and Currier, H. and Tong, A.

DOI: 10.1053/j.ajkd.2018.12.040

Non-invasive differentiation of non-rejection kidney injury from acute rejection in pediatric renal transplant recipients

Pediatric Transplantation

Archdekin, B. and Sharma, A. and Gibson, I.W. and Rush, D. and Wishart, D.S. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.13364

Evolution of renal function and urinary biomarker indicators of inflammation on serial kidney biopsies in pediatric kidney transplant recipients with and without rejection

Pediatric Transplantation

Mincham, C.M. and Gibson, I.W. and Sharma, A. and Wiebe, C. and Mandal, R. and Rush, D. and Nickerson, P. and Ho, J. and Wishart, D.S. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.13202

Estimating Time to ESRD in Children With CKD

American Journal of Kidney Diseases

Furth, S.L. and Pierce, C. and Hui, W.F. and White, C.A. and Wong, C.S. and Schaefer, F. and Whl, E. and Abraham, A.G. and Warady, B.A. and Samuels, J. and Furth, S. and Atkinson, M. and Wilson, A. and Quiroga, A. and Massengill, S. and Selewski, D. and Ferris, M. and Kogon, A. and Kaskel, F. and Lande, M. and Schwartz, G. and Saland, J. and Norwood, V. and Matoo, T. and Hidalgo, G. and Srivaths, P. and Carlson, J. and Langman, C. and Mendley, S. and John, E. and Upadhyay, K. and Seo-Mayer, P. and Patterson, L. and Parekh, R. and Robinson, L. and Weinstein, A. and Samsonov, D. and Kupferman, J. and Misurac, J. and Mongia, A. and Kiessling, S. and Sanchez-Kazi, C. and Dart, A. and Fathallah, S. and Claes, D. and Mitsnefes, M. and Blydt-Hansen, T. and Warady, B. and Greenbaum, L. and Flynn, J. and Wong, C. and Salusky, I. and Yadin, O. and Dell, K. and Jenkins, R. and Pan, C. and Ku, E. and Al-Uzri, A. and Jenkins, R. and Rodig, N. and Wong, C. and Davis, K. and Turman, M. and Bartosh, S. and Hastings, C. and Nayak, A. and Seikaly, M. and Benador, N. and Mak, R. and Wood, E. and Jenkins, R. and Lerner, G. and Barletta, G.M. and Anarat, A. and Bakkaloglu, A. and Ozaltin, F. and Peco-Antic, A. and Querfeld, U. and Gellermann, J. and Sallay, P. and Dro?d?, D. and Bonzel, K.-E. and Wingen, A.-M. and ?urowska, A. and Balasz, I. and Trivelli, A. and Perfumo, F. and Mller-Wiefel, D.E. and Mller, K. and Offner, G. and Enke, B. and Whl, E. and Hadtstein, C. and Mehls, O. and Schaefer, F. and Emre, S. and Caliskan, S. and Mir, S. and Wygoda, S. and Hohbach-Hohenfellner, K. and Jeck, N. and Klaus, G. and Ardissino, G. and Testa, S. and Montini, G. and Charbit, M. and Niaudet, P. and Caldas-Afonso, A. and Fernandes-Teixeira, A. and Du?ek, J. and Matteucci, M.C. and Picca, S. and Mastrostefano, A. and Wigger, M. and Berg, U.B. and Celsi, G. and Fischbach, M. and Terzic, J. and Fydryk, J. and Urasinski, T. and Coppo, R. and Peruzzi, L. and Arbeiter, K. and Jankauskien, A. and Grenda, R. and Litwin, M. and Janas, R. and Neuhaus, T.J.

DOI: 10.1053/j.ajkd.2017.12.011

Determinants of Readiness for Adopting Healthy Lifestyle Behaviors Among Indigenous Adolescents with Type 2 Diabetes in Manitoba, Canada: A Cross-Sectional Study

Obesity

McGavock, J. and Durksen, A. and Wicklow, B. and Malik, S. and Sellers, E.A.C. and Blydt-Hansen, T. and Chateau, D. and Dart, A.

DOI: 10.1002/oby.22148

The prognostic value of urinary chemokines at 6months after pediatric kidney transplantation

Pediatric Transplantation

Mockler, C. and Sharma, A. and Gibson, I.W. and Gao, A. and Wong, A. and Ho, J. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.13205

Practice Patterns in the Treatment and Monitoring of Acute T Cell"Mediated Kidney Graft Rejection in Canada

Canadian Journal of Kidney Health and Disease

Leblanc, J. and Subrt, P. and Par, M. and Hartell, D. and Sncal, L. and Blydt-Hansen, T. and Cardinal, H.

DOI: 10.1177/2054358117753616

Pediatric outcomes in transplant: Personalising immunosuppression to improve efficacy (POSITIVE Study): The collaboration and design of a national transplant precision medicine program

Transplantation Direct

Papaz, T. and Allen, U. and Blydt-Hansen, T. and Birk, P.E. and Min, S. and Hamiwka, L. and Phan, V. and Schechter, T. and Wall, D.A. and Urschel, S. and Foster, B.J. and Mital, S.

DOI: 10.1097/TXD.0000000000000842

Child and Parental Perspectives on Communication and Decision Making in Pediatric CKD: A Focus Group Study

American Journal of Kidney Diseases

Gutman, T. and Hanson, C.S. and Bernays, S. and Craig, J.C. and Sinha, A. and Dart, A. and Eddy, A.A. and Gipson, D.S. and Bockenhauer, D. and Yap, H.-K. and Groothoff, J. and Zappitelli, M. and Webb, N.J.A. and Alexander, S.I. and Goldstein, S.L. and Furth, S. and Samuel, S. and Blydt-Hansen, T. and Dionne, J. and Michael, M. and Wenderfer, S.E. and Winkelmayer, W.C. and Currier, H. and McTaggart, S. and Walker, A. and Ralph, A.F. and Ju, A. and James, L.J. and Carter, S. and Tong, A.

DOI: 10.1053/j.ajkd.2018.05.005

Screening for kidney disease in Indigenous Canadian children: The FINISHED screen, triage and treat program

Paediatrics and Child Health (Canada)

Dart, A. and Lavallee, B. and Chartrand, C. and McLeod, L. and Ferguson, T.W. and Tangri, N. and Gordon, A. and Blydt-Hansen, T. and Rigatto, C. and Komenda, P.

DOI: 10.1093/pch/pxy013

Non-invasive staging of chronic kidney allograft damage using urine metabolomic profiling

Pediatric Transplantation

Landsberg, A. and Sharma, A. and Gibson, I.W. and Rush, D. and Wishart, D.S. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.13226

Successful treatment of chronic norovirus gastroenteritis with nitazoxanide in a pediatric kidney transplant recipient

Pediatric Transplantation

Haubrich, K. and Gantt, S. and Blydt-Hansen, T.

DOI: 10.1111/petr.13186

Vitamin D Status in Indigenous Youth with Type 2 Diabetes

Canadian Journal of Diabetes

Melissa Gabbs and Allison Dart and Farrah Jabar and Kristine Kroeker and Tom Blydt-Hansen and Jon Mcgavock and Brandy Wicklow

DOI: 10.1016/j.jcjd.2017.08.207

10 / 2017

Progression and Regression of Albuminuria in Youth with Type 2 Diabetes

Canadian Journal of Diabetes

Farrah Jabar and Brandy Wicklow and Jonathan McGavock and Elizabeth Sellers and Tom Blydt-Hansen and Kristine Kroeker and Dan Chateau and Allison Dart

DOI: 10.1016/j.jcjd.2017.08.025

10 / 2017

Class II eplet mismatch modulates tacrolimus trough levels required to prevent donor-specific antibody development

Journal of the American Society of Nephrology

Wiebe, C. and Rush, D.N. and Nevins, T.E. and Birk, P.E. and Blydt-Hansen, T. and Gibson, I.W. and Goldberg, A. and Ho, J. and Karpinski, M. and Pochinco, D. and Sharma, A. and Storsley, L. and Matas, A.J. and Nickerson, P.W.

DOI: 10.1681/ASN.2017030287

Design and methods of the pan-canadian applying biomarkers to minimize long-term effects of childhood/adolescent cancer treatment (ABLE) nephrotoxicity study: A prospective observational cohort study

Canadian Journal of Kidney Health and Disease

McMahon, K.R. and Rassekh, S.R. and Schultz, K.R. and Pinsk, M. and Blydt-Hansen, T. and Mammen, C. and Tsuyuki, R.T. and Devarajan, P. and Cuvelier, G.D.E. and Mitchell, L.G. and Baruchel, S. and Palijan, A. and Carleton, B.C. and Ross, C.J.D. and Zappitelli, M.

DOI: 10.1177/2054358117690338

Albuminuria, proteinuria, and renal disease progression in children with CKD

Clinical Journal of the American Society of Nephrology

Fuhrman, D.Y. and Schneider, M.F. and Dell, K.M. and Blydt-Hansen, T.D. and Mak, R. and Saland, J.M. and Furth, S.L. and Warady, B.A. and Moxey-Mims, M.M. and Schwartz, G.J.

DOI: 10.2215/CJN.11971116

Evaluation of C1q Status and Titer of De Novo Donor-Specific Antibodies as Predictors of Allograft Survival

American Journal of Transplantation

Wiebe, C. and Gareau, A.J. and Pochinco, D. and Gibson, I.W. and Ho, J. and Birk, P.E. and Blydt-Hansen, T. and Karpinski, M. and Goldberg, A. and Storsley, L. and Rush, D.N. and Nickerson, P.W.

DOI: 10.1111/ajt.14015

Adverse symptoms of immunosuppressants: A survey of Canadian transplant clinicians

Clinical Transplantation

Harrison, J.J. and Mansell, H. and Blydt-Hansen, T.

DOI: 10.1111/ctr.12940

Urinary Metabolomics for Noninvasive Detection of Antibody-Mediated Rejection in Children after Kidney Transplantation

Transplantation

Blydt-Hansen, T.D. and Sharma, A. and Gibson, I.W. and Wishart, D.S. and Mandal, R. and Ho, J. and Nickerson, P. and Rush, D.

DOI: 10.1097/TP.0000000000001662

C1q status and titer of de novo donor specific antibodies are not predictors of allograft survival

Human Immunology

Chris Wiebe and Alison Gareau and Denise Pochinco and Ian Gibson and Julie Ho and Patricia Birk and Tom Blydt-Hansen and Martin Karpinski and Aviva Goldberg and Leroy Storsley and David Rush and Peter Nickerson

DOI: 10.1016/j.humimm.2016.07.109

09 / 2016

Kidney Disease Progression in Autosomal Recessive Polycystic Kidney Disease.

The Journal of pediatrics

Dell KM and Matheson M and Hartung EA and Warady BA and Furth SL and Chronic Kidney Disease in Children (CKiD) Study

DOI: 10.1016/j.jpeds.2015.12.079 PubMed: 26831744

01 / 2016

Depressive Symptoms in Children with Chronic Kidney Disease

Journal of Pediatrics

Kogon, A.J. and Matheson, M.B. and Flynn, J.T. and Gerson, A.C. and Warady, B.A. and Furth, S.L. and Hooper, S.R. and Dart, A. and Greenbaum, L. and Goebel, J. and Mitsnefes, M. and Wong, C. and Fathallah, S. and Salusky, I. and Yadin, O. and Dell, K. and Morgenstern, B. and Blydt-Hansen, T. and Pan, C. and Davis, K. and Al-Uzri, A. and Jenkins, R. and Portale, A. and Seikaly, M. and Turman, M. and Wong, C. and Alexander, S. and Hastings, C. and Rodig, N. and Harmon, W. and Bartosh, S. and Benador, N. and Mak, R. and Wood, E. and Lerner, G. and Massengill, S. and Hidalgo, G. and Atkinson, M. and Gipson, D. and Srivaths, P. and Samuels, J. and Kaskel, F. and Mattosian, D. and Cai, Y. and Andreoli, S. and Saland, J. and Norwood, V. and Parekh, R. and Robinson, L. and Mendley, S. and Lande, M. and Schwartz, G. and Brophy, P. and John, E. and Upadhyay, K. and Ferris, M. and Matoo, T. and Kupferman, J. and Weiss, L. and Langman, C. and Seo-Mayer, P. and Kher, K. and Samsonov, D.

DOI: 10.1016/j.jpeds.2015.09.040

Genetic loci associated with renal function measures and chronic kidney disease in children: The Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium

Nephrology Dialysis Transplantation

Wuttke, M. and Wong, C.S. and Whl, E. and Epting, D. and Luo, L. and Hoppmann, A. and Doyon, A. and Li, Y. and Szeri, B. and Thurn, D. and Helmstdter, M. and Huber, T.B. and Blydt-Hansen, T.D. and Kramer-Zucker, A. and Mehls, O. and Melk, A. and Querfeld, U. and Furth, S.L. and Warady, B.A. and Schaefer, F. and Kttgen, A.

DOI: 10.1093/ndt/gfv342

Canadian Forum on Combined Organ Transplantation

Transplantation

Cantarovich, M. and Blydt-Hansen, T.D. and Gill, J. and Tinckam, K. and Schiff, J. and Alwayn, I. and Bain, V. and Dipchand, A.I. and Isaac, D. and Kim, S.J. and Lien, D. and Zaltzman, J. and Young, K. and Nickerson, P.

DOI: 10.1097/TP.0000000000000963

Elevated urinary CXCL10-to-creatinine ratio is associated with subclinical and clinical rejection in pediatric renal transplantation

Transplantation

Blydt-Hansen, T.D. and Gibson, I.W. and Gao, A. and Dufault, B. and Ho, J.

DOI: 10.1097/TP.0000000000000419

Beating Diabetes Together: A Mixed-Methods Analysis of a Feasibility Study of Intensive Lifestyle Intervention for Youth with Type 2 Diabetes

Canadian Journal of Diabetes

Huynh, E. and Rand, D. and McNeill, C. and Brown, S. and Senechal, M. and Wicklow, B. and Dart, A. and Sellers, E. and Dean, H. and Blydt-Hansen, T. and McGavock, J.

DOI: 10.1016/j.jcjd.2015.09.093

Rates and determinants of progression to graft failure in kidney allograft recipients with de novo donor-specific antibody

American Journal of Transplantation

Wiebe, C. and Gibson, I.W. and Blydt-Hansen, T.D. and Pochinco, D. and Birk, P.E. and Ho, J. and Karpinski, M. and Goldberg, A. and Storsley, L. and Rush, D.N. and Nickerson, P.W.

DOI: 10.1111/ajt.13347

Progression of pediatric CKD of nonglomerular origin in the CKiD cohort

Clinical Journal of the American Society of Nephrology

Fathallah-Shaykh, S.A. and Flynn, J.T. and Pierce, C.B. and Abraham, A.G. and Blydt-Hansen, T.D. and Massengill, S.F. and Moxey-Mims, M.M. and Warady, B.A. and Furth, S.L. and Wong, C.S.

DOI: 10.2215/CJN.07480714

Description of a Novel Collaborative Joint Pediatric Renal and Type 2 Diabetes Clinic

Canadian Journal of Diabetes

Megan Bale and Tom Blydt-Hansen and Julie Halipchuk and Allison Dart and Brandy Wicklow

DOI: 10.1016/j.jcjd.2014.07.093

10 / 2014

Guidance on the use of increased infectious risk donors for organ transplantation.

Transplantation

DOI: 10.1097/tp.0000000000000251 PubMed: 25243510

08 / 2014

Effect of sirolimus on malignancy and survival after kidney transplantation: Systematic review and meta-analysis of individual patient data

BMJ (Online)

Knoll, G.A. and Kokolo, M.B. and Mallick, R. and Beck, A. and Buenaventura, C.D. and Ducharme, R. and Barsoum, R. and Bernasconi, C. and Blydt-Hansen, T.D. and Ekberg, H. and Felipe, C.R. and Firth, J. and Gallon, L. and Gelens, M. and Glotz, D. and Gossmann, J. and Guba, M. and Morsy, A.A. and Salgo, R. and Scheuermann, E.H. and Tedesco-Silva, H. and Vitko, S. and Watson, C. and Fergusson, D.A.

DOI: 10.1136/bmj.g6679

The Improving Renal Complications in Adolescents With Type 2 Diabetes Through the REsearch (iCARE) Cohort Study: Rationale and Protocol

Canadian Journal of Diabetes

Dart, A.B. and Wicklow, B.A. and Sellers, E.A. and Dean, H.J. and Malik, S. and Walker, J. and Chateau, D. and Blydt-Hansen, T.D. and McGavock, J.M.

DOI: 10.1016/j.jcjd.2014.07.224

Meeting report: Consensus recommendations for a research agenda in exercise in solid organ transplantation

American Journal of Transplantation

Mathur, S. and Janaudis-Ferreira, T. and Wickerson, L. and Singer, L.G. and Patcai, J. and Rozenberg, D. and Blydt-Hansen, T. and Hartmann, E.L. and Haykowsky, M. and Helm, D. and High, K. and Howes, N. and Kamath, B.M. and Lands, L. and Marzolini, S. and Sonnenday, C.

DOI: 10.1111/ajt.12874

Skeletal findings in the first 12 months following initiation of glucocorticoid therapy for pediatric nephrotic syndrome

Osteoporosis International

Phan, V. and Blydt-Hansen, T. and Feber, J. and Alos, N. and Arora, S. and Atkinson, S. and Bell, L. and Clarson, C. and Couch, R. and Cummings, E.A. and Filler, G. and Grant, R.M. and Grimmer, J. and Hebert, D. and Lentle, B. and Ma, J. and Matzinger, M. and Midgley, J. and Pinsk, M. and Rodd, C. and Shenouda, N. and Stein, R. and Stephure, D. and Taback, S. and Williams, K. and Rauch, F. and Siminoski, K. and Ward, L.M. and Halton, J. and Jurencak, R. and Roth, J. and Moher, D. and Ramsay, T. and Kloiber, R. and Lewis, V. and Miettunen, P. and Cabral, D. and Dix, D.B. and Houghton, K. and Nadel, H.R. and Hay, J. and Cairney, E. and Sparrow, K. and Fernandez, C. and Huber, A.M. and Lang, B. and O'Brien, K. and Barr, R. and Coblentz, C. and Dent, P.B. and Larche, M. and Webber, C. and Abish, S. and Scuccimarri, R. and Glorieux, F. and Dubois, J. and Laverdire, C. and Saint-Cyr, C. and Ellsworth, J. and LeBlanc, C. and Wilson, B. and Charron, M. and Gaboury, I. and Israels, S. and Oen, K. and Reed, M.

DOI: 10.1007/s00198-013-2466-7

Medication treatment complexity and adherence in children with CKD

Clinical Journal of the American Society of Nephrology

Blydt-Hansen, T.D. and Pierce, C.B. and Cai, Y. and Samsonov, D. and Massengill, S. and Moxey-Mims, M. and Warady, B.A. and Furth, S.L.

DOI: 10.2215/CJN.05750513

Antibody-mediated rejection: Analyzing the risk, proposing solutions

Transplantation

Arias, M. and Rush, D.N. and Wiebe, C. and Gibson, I.W. and Blydt-Hansen, T.D. and Nickerson, P.W. and Sellars, J. and Lpez-Hoyos, M. and San Segundo, D. and Crespo-Leiro, M.G. and Marzoa-Rivas, R. and Barge-Caballero, E. and Paniagua-Martn, M.J. and Romn, A. and Sern, D. and Bhmig, G. and Schwaiger, E.

DOI: 10.1097/TP.0000000000000218

Urinary metabolomics for noninvasive detection of borderline and acute T cell-mediated rejection in children after kidney transplantation

American Journal of Transplantation

Blydt-Hansen, T.D. and Sharma, A. and Gibson, I.W. and Mandal, R. and Wishart, D.S.

DOI: 10.1111/ajt.12837

How should we identify early chronic kidney disease risk in non-kidney transplant recipients?

Pediatric Transplantation

Blydt-Hansen, T.D. and Dart, A.B.

DOI: 10.1111/petr.12356

Evidence for the use of glomerulomegaly as a surrogate marker of glomerular damage and for alpha-linolenic acid-rich oils in the treatment of early obesity-related glomerulopathy in a diet-induced rodent model of obesity

Applied Physiology, Nutrition and Metabolism

Caligiuri, S.P.B. and Blydt-Hansen, T. and Love, K. and Grgoire, M. and Taylor, C.G. and Zahradka, P. and Aukema, H.M.

DOI: 10.1139/apnm-2013-0476

Canadian society of nephrology commentary on the 2012 KDIGO clinical practice guideline for the management of blood pressure in CKD

American Journal of Kidney Diseases

Ruzicka, M. and Quinn, R.R. and McFarlane, P. and Hemmelgarn, B. and Ramesh Prasad, G.V. and Feber, J. and Nesrallah, G. and Mackinnon, M. and Tangri, N. and McCormick, B. and Tobe, S. and Blydt-Hansen, T.D. and Hiremath, S.

DOI: 10.1053/j.ajkd.2014.03.003

The impact of short stature on health-related quality of life in children with chronic kidney disease.

The Journal of pediatrics

Al-Uzri A and Matheson M and Gipson DS and Mendley SR and Hooper SR and Yadin O and Rozansky DJ and Moxey-Mims M and Furth SL and Warady BA and Gerson AC and Chronic Kidney Disease in Children Study Group

DOI: 10.1016/j.jpeds.2013.03.016 PubMed: 23628375

04 / 2013

Substantial practice variation exists in the management of childhood nephrotic syndrome

Pediatric Nephrology

Samuel, S. and Morgan, C.J. and Bitzan, M. and Mammen, C. and Dart, A.B. and Manns, B.J. and Alexander, R.T. and Erickson, R.L. and Grisaru, S. and Wade, A.W. and Blydt-Hansen, T. and Feber, J. and Arora, S. and Licht, C. and Zappitelli, M.

DOI: 10.1007/s00467-013-2546-0

Association of income level with kidney disease severity and progression among children and adolescents with CKD: A report from the chronic kidney disease in children (CKiD) study

American Journal of Kidney Diseases

Hidalgo, G. and Ng, D.K. and Moxey-Mims, M. and Minnick, M.L. and Blydt-Hansen, T. and Warady, B.A. and Furth, S.L.

DOI: 10.1053/j.ajkd.2013.06.013

Class II HLA epitope matching - A strategy to minimize de novo donor-specific antibody development and improve outcomes

American Journal of Transplantation

Wiebe, C. and Pochinco, D. and Blydt-Hansen, T.D. and Ho, J. and Birk, P.E. and Karpinski, M. and Goldberg, A. and Storsley, L.J. and Gibson, I.W. and Rush, D.N. and Nickerson, P.W.

DOI: 10.1111/ajt.12478

The development of bone mineral lateralization in the arms

Osteoporosis International

Siminoski, K. and Lee, K.-C. and Abish, S. and Alos, N. and Bell, L. and Blydt-Hansen, T. and Couch, R. and Cummings, E.A. and Ellsworth, J. and Feber, J. and Fernandez, C.V. and Halton, J. and Huber, A.M. and Israels, S. and Jurencak, R. and Lang, B. and Laverdire, C. and Leblanc, C. and Lewis, V. and Midgley, J. and Miettunen, P.M. and Oen, K. and Phan, V. and Pinsk, M. and Rauch, F. and Rodd, C. and Roth, J. and Saint-Cyr, C. and Scuccimarri, R. and Stephure, D. and Taback, S. and Wilson, B. and Ward, L.M.

DOI: 10.1007/s00198-012-2054-2

Dietary linoleic acid and a-linolenic acid differentially affect renal oxylipins and phospholipid fatty acids in diet-induced obese rats

Journal of Nutrition

Caligiuri, S.P.B. and Love, K. and Winter, T. and Gauthier, J. and Taylor, C.G. and Blydt-Hansen, T. and Zahradka, P. and Aukema, H.M.

DOI: 10.3945/jn.113.177360

Pediatric kidney transplant practice patterns and outcome benchmarks, 1987-2010: A report of the North American Pediatric Renal Trials and Collaborative Studies

Pediatric Transplantation

Smith, J.M. and Martz, K. and Blydt-Hansen, T.D.

DOI: 10.1111/petr.12034

Assessment of identity and quality of life in diabetic and renal transplant adolescents in comparison to healthy adolescents

Journal of Clinical Psychology in Medical Settings

Lugasi, T. and Achille, M. and Blydt-Hansen, T. and Clermont, M.-J. and Geoffroy, L. and Legault, L. and Phan, V. and Bell, L.E.

DOI: 10.1007/s10880-012-9344-x

Incident vertebral fractures among children with rheumatic disorders 12 months after glucocorticoid initiation: a national observational study.

Arthritis care & research

DOI: 10.1002/acr.20589 PubMed: 22213727

01 / 2012

Skeletal findings in children recently initiating glucocorticoids for the treatment of nephrotic syndrome

Osteoporosis International

Feber, J. and Gaboury, I. and Ni, A. and Alos, N. and Arora, S. and Bell, L. and Blydt-Hansen, T. and Clarson, C. and Filler, G. and Hay, J. and Hebert, D. and Lentle, B. and Matzinger, M. and Midgley, J. and Moher, D. and Pinsk, M. and Rauch, F. and Rodd, C. and Shenouda, N. and Siminoski, K. and Ward, L.M.

DOI: 10.1007/s00198-011-1621-2

Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant

American Journal of Transplantation

Wiebe, C. and Gibson, I.W. and Blydt-Hansen, T.D. and Karpinski, M. and Ho, J. and Storsley, L.J. and Goldberg, A. and Birk, P.E. and Rush, D.N. and Nickerson, P.W.

DOI: 10.1111/j.1600-6143.2012.04013.x

Reliability of resting blood pressure measurement and classification using an oscillometric device in children with chronic kidney disease.

The Journal of pediatrics

Flynn JT and Pierce CB and Miller ER and Charleston J and Samuels JA and Kupferman J and Furth SL and Warady BA and Chronic Kidney Disease in Children Study Group

DOI: 10.1016/j.jpeds.2011.08.071 PubMed: 22048052

11 / 2011

Pretransplant serologic testing to identify the risk of polyoma BK viremia in pediatric kidney transplant recipients

Pediatric Transplantation

Ali, A.M. and Gibson, I.W. and Birk, P. and Blydt-Hansen, T.D.

DOI: 10.1111/j.1399-3046.2011.01583.x

Transplantation outcomes in primary hyperoxaluria.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Bergstralh EJ and Monico CG and Lieske JC and Herges RM and Langman CB and Hoppe B and Milliner DS and IPHR Investigators

DOI: 10.1111/j.1600-6143.2010.03271.x PubMed: 20849551

09 / 2010

Canadian Society of Transplantation and Canadian Society of Nephrology commentary on the 2009 KDIGO clinical practice guideline for the care of kidney transplant recipients

American Journal of Kidney Diseases

Knoll, G.A. and Blydt-Hansen, T.D. and Campbell, P. and Cantarovich, M. and Cole, E. and Fairhead, T. and Gill, J.S. and Gourishankar, S. and Hebert, D. and Hodsman, A. and House, A.A. and Humar, A. and Karpinski, M. and Kim, S.J. and Mainra, R. and Prasad, G.V.R.

DOI: 10.1053/j.ajkd.2010.05.004

Policy statement of canadian society of transplantation and canadian society of nephrology on organ trafficking and transplant tourism

Transplantation

Gill, J.S. and Goldberg, A. and Prasad, G.V.R. and Fortin, M.-C. and Hansen, T.-B. and Levin, A. and Gill, J. and Tonelli, M. and Tibbles, L.A. and Knoll, G. and Cole, E.H. and Caulfield, T.

DOI: 10.1097/TP.0b013e3181efd030

Masked hypertension associates with left ventricular hypertrophy in children with CKD

Journal of the American Society of Nephrology

Mitsnefes, M. and Flynn, J. and Cohn, S. and Samuels, J. and Blydt-Hansen, T. and Saland, J. and Kimball, T. and Furth, S. and Warady, B.

DOI: 10.1681/ASN.2009060609

Prevalent vertebral fractures among children initiating glucocorticoid therapy for the treatment of rheumatic disorders

Arthritis Care and Research

Huber, A.M. and Gaboury, I. and Cabral, D.A. and Lang, B. and Ni, A. and Stephure, D. and Taback, S. and Dent, P. and Ellsworth, J. and LeBlanc, C. and Saint-Cyr, C. and Scuccimarri, R. and Hay, J. and Lentle, B. and Matzinger, M. and Shenouda, N. and Moher, D. and Rauch, F. and Siminoski, K. and Ward, L.M. and Feber, J. and Halton, J. and Roth, J. and Kloiber, R. and Lewis, V. and Midgley, J. and Miettunen, P. and Dix, D.B. and Houghton, K. and Nadel, H.R. and White, C. and Clarson, C. and Stein, R. and Cairney, E. and Filler, G. and Grimmer, J. and Sparrow, K. and Cummings, E. and Fernandez, C. and O'Brien, K. and Ross, A. and Atkinson, S. and Arora, S. and Barr, R. and Coblentz, C. and Webber, C. and Rodd, C. and Abish, S. and Bell, L. and Glorieux, F. and Alos, N. and Dubois, J. and Laverdire, C. and Phan, V. and Couch, R. and Pinsk, M. and Wilson, B. and Grant, R. and Charron, M. and Hebert, D. and Blydt-Hansen, T. and Israels, S. and Oen, K. and Reed, M.

DOI: 10.1002/acr.20171

Histological progression of chronic renal allograft injury comparing sirolimus and mycophenolate mofetil-based protocols. A single-center, prospective, randomized, controlled study

Pediatric Transplantation

Blydt-Hansen, T.D. and Gibson, I.W. and Birk, P.E.

DOI: 10.1111/j.1399-3046.2010.01374.x

Enhanced resolution of interstitial fibrosis in pediatric renal allograft biopsies using image analysis of trichrome stain

Pediatric Transplantation

Birk, P.E. and Gill, J.S. and Blydt-Hansen, T.D. and Gibson, I.W.

DOI: 10.1111/j.1399-3046.2010.01376.x

The Use of Immunoglobulin Therapy for Patients Undergoing Solid Organ Transplantation: An Evidence-Based Practice Guideline

Transfusion Medicine Reviews

Shehata, N. and Palda, V.A. and Meyer, R.M. and Blydt-Hansen, T.D. and Campbell, P. and Cardella, C. and Martin, S. and Nickerson, P. and Peltekian, K. and Ross, H. and Waddell, T.K. and West, L. and Anderson, D. and Freedman, J. and Hume, H.

DOI: 10.1016/j.tmrv.2009.09.010

Patterns of chronic injury in pediatric renal allografts

Transplantation

Dart, A.B. and Schall, A. and Gibson, I.W. and Blydt-Hansen, T.D. and Birk, P.E.

DOI: 10.1097/TP.0b013e3181bc5e49

Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: Results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program

Journal of Bone and Mineral Research

Halton, J. and Gaboury, I. and Grant, R. and Alos, N. and Cummings, E.A. and Matzinger, M. and Shenouda, N. and Lentle, B. and Abish, S. and Atkinson, S. and Cairney, E. and Dix, D. and Israels, S. and Stephure, D. and Wilson, B. and Hay, J. and Moher, D. and Rauch, F. and Siminoski, K. and Ward, L.M. and Feber, J. and Roth, J. and Kloiber, R. and Lewis, V. and Midgley, J. and Miettunen, P. and Cabral, D. and Nadel, H.R. and White, C. and Clarson, C. and Filler, G. and Grimmer, J. and Sparrow, K. and Fernandez, C. and Huber, A.M. and Lang, B. and O'Brien, K. and Ross, A. and Arora, S. and Barr, R. and Coblentz, C. and Dent, P.B. and Webber, C. and Rodd, C. and Bell, L. and Scuccimarri, R. and Glorieux, F. and Dubois, J. and Laverdire, C. and Phan, V. and Saint-Cyr, C. and Couch, R. and Ellsworth, J. and LeBlanc, C. and Pinsk, M. and Charron, M. and Hebert, D. and Taback, S. and Blydt-Hansen, T. and Oen, K. and Reed, M.

DOI: 10.1359/jbmr.090202

The concurrent presentation of minimal change nephrotic syndrome and aplastic anemia

Pediatric Nephrology

Abrams, E.M. and Gibson, I.W. and Blydt-Hansen, T.D.

DOI: 10.1007/s00467-008-0994-8

Impact of socioeconomic status on the prevalence of dementia in an inner city memory disorders clinic

International Psychogeriatrics

Fischer, C. and Yeung, E. and Hansen, T. and Gibbons, S. and Fornazzari, L. and Ringer, L. and Schweizer, T.A.

DOI: 10.1017/S1041610209990846

Macroalbuminuria and renal pathology in first nation youth with type 2 diabetes

Diabetes Care

Sellers, E.A.C. and Blydt-Hansen, T.D. and Dean, H.J. and Gibson, I.W. and Birk, P.E. and Ogborn, M.

DOI: 10.2337/dc08-1828

Knowledge of Alzheimer's disease and subjective memory impairment in Latin American seniors in the Greater Toronto Area

International Psychogeriatrics

Fornazzari, L. and Fischer, C. and Hansen, T. and Ringer, L.

DOI: 10.1017/S1041610209990433

Changes in height, BMI and bone density in children with nephrotic syndrome during six months prospective follow-up

American Society of Nephrology

J Feber, S Arora, L Bell, T Blydt-Hansen, G Filler, J Grimmer, D Hebert, J P Midgley, V Phan, M Pinsk, L M Ward and the STOPP Consortium.(2008). Changes in height, BMI and bone density in children with nephrotic syndrome during six months prospective follow-up. American Society of Nephrology. Co-Author Published, United States Number of Contributors: 12

Low incidence of adverse events in outpatient pediatric renal allograft biopsies

Pediatric Transplantation

Birk, P.E. and Blydt-Hansen, T.D. and Dart, A.B. and Kaita, L.M. and Proulx, C. and Taylor, G.

DOI: 10.1111/j.1399-3046.2006.00659.x

Pediatric ESRD in Canada: A review of the last quarter century

CIHI Annual Report

Biopsy-proven acute tubular necrosis in a child attributed to vancomycin intoxication

Pediatric Nephrology

Wicklow, B.A. and Ogborn, M.R. and Gibson, I.W. and Blydt-Hansen, T.D.

DOI: 10.1007/s00467-006-0152-0

Canadian Society of Transplantation consensus guidelines on eligibility for kidney transplantation

CMAJ

Knoll, G. and Cockfield, S. and Blydt-Hansen, T. and Baran, D. and Kiberd, B. and Landsberg, D. and Rush, D. and Cole, E.

DOI: 10.1503/cmaj.051291

Canadian Society of Transplantation: consensus guidelines on eligibility for kidney transplantation.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

Knoll, G. and Cockfield, S. and Blydt-Hansen, T. and Baran, D. and Kiberd, B. and Landsberg, D. and Rush, D. and Cole, E.

DOI: 10.1503/cmaj.1041588

Erratum: Canadian Society of Transplantation consensus guidelines on eligibility for kidney transplantation (Canadian Medical Association Journal (2005) 173, 10 (1181-1184)) DOI: 10.1503/cmaj.051291

CMAJ

Knoll, G. and Cockfield, S. and Blydt-Hansen, T.

DOI: 10.1503/cmaj.051428

Surveillance biopsies are superior to functional studies for the diagnosis of acute and chronic renal allograft pathology in children

Pediatric Transplantation

Birk, P.E. and Stannard, K.M. and Konrad, H.B. and Blydt-Hansen, T.D. and Ogborn, M.R. and Cheang, M.S. and Gartner, J.G. and Gibson, I.W.

DOI: 10.1046/j.1397-3142.2003.00122.x

Children are not small adults.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 12566324

02 / 2003

Children are not small adults [1]

CMAJ

Dean, H. and Sellers, E. and Birk, P. and Blydt-Hansen, T. and Ogborn, M. and Tobe, S.

Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury

Journal of the American Society of Nephrology

Blydt-Hansen, T.D. and Katori, M. and Lassman, C. and Ke, B. and Coito, A.J. and Iyer, S. and Buelow, R. and Ettenger, R. and Busuttil, R.W. and Kupiec-Weglinski, J.W.

DOI: 10.1097/01.ASN.0000050760.87113.25

Recovery of respiratory syncytial virus from stethoscopes by conventional viral culture and polymerase chain reaction

Pediatric Infectious Disease Journal

Blydt-Hansen, T. and Subbarao, K. and Quennec, P. and McDonald, J.

DOI: 10.1097/00006454-199902000-00017

PHEX expression in parathyroid gland and parathyroid hormone dysregulation in X-linked hypophosphatemia

Pediatric Nephrology

Blydt-Hansen, T.D. and Tenenhouse, H.S. and Goodyer, P.

DOI: 10.1007/s004670050669

The CNTRP (Canadian National Transplant Research Program)

is a CIHR co-funded large network of researchers who are collectively undertaking 6 unique research programs that are supported by 3 cores. This includes a pediatric solid organ transplant research program that will focus on age and developmental changes in the immune system, drug pharmacokinetics, viral infection susceptibility and systems-related issues affecting adherence across the spectrum of mid and late-adolescence.

The PROBE Multicenter Cohort study

(Pediatric Renal transplant Optimization using BiomarkErs) is a CHIR funded program to identify urine biomarkers of kidney allograft injury such as acute rejection, in children after kidney transplantation. It follows on an initial cohort study that has identified urinary chemokines and metabolite profiles that accurately detect acute rejecton. The current study will validate these findings in a multi-center cohort, establish the time-course for appearance and disappearance of "risk" signals in the first year after transplant, and deterimine the whether these events which are not otherwise detectable are associated with worse long-term outcome as measured by histology, kidney function and development of de novo donor-specific antibodies.

Grants

Canadian Institutes of Health Research (CIHR) “Applying Biomarkers to Long-term Effects in Child and Adolescent Cancer Treatment (ABLE Team).” Oct 2011-Sep 2016. PI: Schultz, Kirk Raymond, Tom Blydt-Hansen (collaborator), L.R. Brandao, R. Broady, B.C. Carleton, G. Cuvelier, M.R. Hayden, A.Y.Y. Lee, M.N.Pinsk, C.J.D. Ross, M. Spavor.

Astellas Pharma Canada, Inc. “PROBE-Adherence: Therapeutic drug exposure and outcome in pediatric kidney transplant recipients converting from twice-daily tacrolimus to daily extended-release tacrolimus.” Apr 2014- Sept 2018. PI: Tom Blydt-Hansen, Beth Foster, Ian Gibson, Julie Ho, Peter Nickerson, Atul Sharma, David Wishart.

Canadian Diabetes Association “Improving cardiovascular risk in adolescents with diabetes through research (iCARE).” Jan 2011-Dec 2014. PI: Allison Dart, Tom Blydt-Hansen (co-investigator), J. McGavock, E. Sellers, H. Dean.

Children's Hospital Foundation of Manitoba. "Pediatric Kidney Health and Transplant Education Resource: Pre-Transplant". December 2014. April 1 2015 - March 30 2016. PI: Julie Strong, Tom Blydt-Hansen.

Canadian Institutes of Health Research (CIHR) “Non-Invasive monitoring of pediatric kidney allograft injury to improve diagnosis and patient outcomes” Oct 2012- Sep 2017. PI: Tom Blydt-Hansen, Julie Ho, Peter Nickerson, David Wishart, Ian Gibson.

Canadian Institutes of Health Research (CIHR) “Canadian National Transplant Research Program (CNTRP).” Apr 2013- Mar 2018. PI: West L. Caulfield T, Hebert MJ, Humar A, Knoll G, Levings M, Mital S, Roy DC, Schultz K, Shapiro J, Tom Blydt-Hansen.

Astellas Canada "PROBE Adherence: Therapeutic drug exposure and outcome in pediatric kidney transplant recipients converting from twice-daily tacrolimus to daily extended-release tacrolimus". June 2014 - May 2018. PI: Tom Blydt-Hansen.

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