Overview

My research aims to improve women's reproductive health in three different areas: 1) Improving safe prescribing and treatment for women suffering from mental health conditions during the perinatal period in order to improve both their health and the health of their infants and children; 2) Improving prevention of gynecologic cancers, and; 3) Improving the provision of health care during pregnancy, labour and delivery.

Publications

Use of biologics during pregnancy and risk of serious infections in the mother and baby: a Canadian population-based cohort study
BMJ Open
Nicole W Tsao and Larry D Lynd and Eric C Sayre and Mohsen Sadatsafavi and Gillian Hanley and Mary A De Vera
DOI: 10.1136/bmjopen-2018-023714
02/2019

Selected medical interventions in women with a deleterious BRCA mutation: a population-based study in British Columbia
Current Oncology
G. E. Hanley and J. N. McAlpine and R. Cheifetz and K. A. Schrader and M. McCullum and D. Huntsman
DOI: 10.3747/co.26.4068
02/2019

Association of Prenatal Exposure to Air Pollution With Autism Spectrum Disorder
JAMA Pediatrics
Lief Pagalan and Celeste Bickford and Whitney Weikum and Bruce Lanphear and Michael Brauer and Nancy Lanphear and Gillian E. Hanley and Tim F. Oberlander and Meghan Winters
DOI: 10.1001/jamapediatrics.2018.3101
01/2019

Long-term mortality among women with epithelial ovarian cancer: a population-based study in British Columbia, Canada
BMC Cancer
Nimisha Arora and Aline Talhouk and Jessica N. McAlpine and Michael R. Law and Gillian E. Hanley
DOI: 10.1186/s12885-018-4970-9
10/2018

Extending the safety evidence for opportunistic salpingectomy in prevention of ovarian cancer: a cohort study from British Columbia, Canada
American Journal of Obstetrics and Gynecology
Gillian E. Hanley and Janice S. Kwon and Sarah J. Finlayson and David G. Huntsman and Dianne Miller and Jessica N McAlpine
DOI: 10.1016/j.ajog.2018.05.019
08/2018

Outcomes of Conservative Management of High Grade Squamous Intraepithelial Lesions in Young Women
Journal of Lower Genital Tract Disease
Marette H. Lee and Sarah J. Finlayson and Ksenia Gukova and Gillian Hanley and Dianne Miller and Leslie Ann Sadownik
DOI: 10.1097/lgt.0000000000000399
07/2018

Changing Clinical Practice: Evaluation of Implementing Recommendations for Opportunistic Salpingectomy in British Columbia and Ontario.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
DOI: 10.1097/igc.0000000000001288
PubMed: 29757870
07/2018

Outcomes of Conservative Management of High Grade Squamous Intraepithelial Lesions in Young Women.
Journal of lower genital tract disease
DOI: 10.1097/LGT.0000000000000399
PubMed: 29762428
07/2018

Socioeconomic status and treatment of depression during pregnancy: a retrospective population-based cohort study in British Columbia, Canada
Archives of Women's Mental Health
Gillian E. Hanley and Mina Park and Tim F. Oberlander
DOI: 10.1007/s00737-018-0866-6
06/2018

BRCA Mutation Testing for First-Degree Relatives of Women With High-Grade Serous Ovarian Cancer [4OP]
Obstetrics & Gynecology
Janice S. Kwon and Anna Tinker and Gillian Hanley and Gary Pansegrau and Mark S. Carey and Kasmintan Schrader
DOI: 10.1097/01.aog.0000533292.16410.11
05/2018

Patterns of Biologics Utilization and Discontinuation Before and During Pregnancy in Women With Autoimmune Diseases: A Population-Based Cohort Study.
Arthritis care & research
DOI: 10.1002/acr.23434
PubMed: 28973840
04/2018

Risk of preterm delivery and small-for-gestational-age births in women with autoimmune disease using biologics before or during pregnancy: a population-based cohort study
Annals of the Rheumatic Diseases
Nicole W Tsao and Eric C Sayre and Gillian Hanley and Mohsen Sadatsafavi and Larry D Lynd and Carlo A Marra and Mary A De Vera
DOI: 10.1136/annrheumdis-2018-213023
03/2018

A population-based analysis of germline BRCA1 and BRCA2 testing among ovarian cancer patients in an era of histotype-specific approaches to ovarian cancer prevention.
BMC cancer
DOI: 10.1186/s12885-018-4153-8
PubMed: 29506471
03/2018

Causes of death among women with epithelial ovarian cancer by length of survival post-diagnosis: a population-based study in British Columbia, Canada
International Journal of Gynecologic Cancer
Nimisha Arora and Aline Talhouk and Jessica N. McAlpine and Michael R. Law and Gillian E. Hanley
DOI: 10.1136/ijgc-2018-000040
2018

Depressed Women of Low Socioeconomic Status Have High Numbers of Physician Visits in the Year Before Pregnancy: Implications for Care
Journal of Clinical Medicine Research
Jenny Fairthorne and Gillian E. Hanley and Tim F. Oberlander
DOI: 10.14740/jocmr3377w
2018

Risk-reducing Surgery in Women at Low Lifetime Risk of Developing Ovarian Carcinoma: Opportunistic Salpingectomy.
Clinical obstetrics and gynecology
DOI: 10.1097/grf.0000000000000315
PubMed: 28957952
12/2017

2009 IOM guidelines for gestational weight gain: how well do they predict outcomes across ethnic groups?
Ethnicity & Health
Amal R. Khanolkar and Gillian E. Hanley and Ilona Koupil and Patricia A. Janssen
DOI: 10.1080/13557858.2017.1398312
11/2017

An Economic Model of Professional Doula Support in Labor in British Columbia, Canada
Journal of Midwifery & Women's Health
Gillian E. Hanley and Lily Lee
DOI: 10.1111/jmwh.12643
09/2017

In Reply
Obstetrics & Gynecology
Gillian E. Hanley and Jennifer A. Hutcheon and Brooke A. Kinniburgh and Lily Lee
DOI: 10.1097/aog.0000000000002175
08/2017

Interpregnancy Interval and Adverse Pregnancy Outcomes: An Analysis of Successive Pregnancies and: Interpregnancy Interval and Pregnancy Outcomes: Causal or Not?
Obstetrics and gynecology
DOI: 10.1097/aog.0000000000002171
PubMed: 28742651
08/2017

Response to “use of domperidone and risk of ventricular arrhythmia in the postpartum period: Getting to the heart of the matter”
Pharmacoepidemiology and Drug Safety
Kate Smolina and Steve Morgan and Barbara Mintzes and Gillian Hanley and Tim Oberlander
DOI: 10.1002/pds.4229
07/2017

Interpregnancy Interval and Adverse Pregnancy Outcomes
Obstetrics & Gynecology
Gillian E. Hanley and Jennifer A. Hutcheon and Brooke A. Kinniburgh and Lily Lee
DOI: 10.1097/aog.0000000000001891
03/2017

The performance and safety of bilateral salpingectomy for ovarian cancer prevention in the United States
American Journal of Obstetrics and Gynecology
Gillian Elizabeth Hanley and Jessica Nell McAlpine and Celeste Leigh Pearce and Dianne Miller
DOI: 10.1016/j.ajog.2016.10.035
03/2017

A Predictive Model for Cesarean Among Low-Risk Nulliparous Women in Spontaneous Labor at Hospital Admission
Birth
Patricia A. Janssen and Jozette J. C. Stienen and Rollin Brant and Gillian E. Hanley
DOI: 10.1111/birt.12257
10/2016

In Reply
Obstetrics & Gynecology
Gillian E. Hanley and Barbara Mintzes
DOI: 10.1097/aog.0000000000001542
08/2016

The association between domperidone and ventricular arrhythmia in the postpartum period
Pharmacoepidemiology and Drug Safety
Kate Smolina and Barbara Mintzes and Gillian E. Hanley and Tim F. Oberlander and Steven G. Morgan
DOI: 10.1002/pds.4035
06/2016

Opportunistic Salpingectomy: We Chose to Act, Not Wait
Journal of Obstetrics and Gynaecology Canada
Jessica N. McAlpine and Alicia A. Tone and Gillian E. Hanley
DOI: 10.1016/j.jogc.2016.04.084
05/2016

La salpingectomie opportuniste : Nous choisissons d'agir, pas d'attendre.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
DOI: 10.1016/j.jogc.2016.04.090
PubMed: 27261216
05/2016

Diagnosing onset of labor: a systematic review of definitions in the research literature
BMC Pregnancy and Childbirth
Gillian E. Hanley and Sarah Munro and Devon Greyson and Mechthild M. Gross and Vanora Hundley and Helen Spiby and Patricia A. Janssen
DOI: 10.1186/s12884-016-0857-4
04/2016

Postpartum Hemorrhage and Use of Serotonin Reuptake Inhibitor Antidepressants in Pregnancy
Obstetrics & Gynecology
Gillian E. Hanley and Kate Smolina and Barbara Mintzes and Tim F. Oberlander and Steven G. Morgan
DOI: 10.1097/aog.0000000000001200
03/2016

Postpartum domperidone use in British Columbia: a retrospective cohort study
CMAJ Open
K. Smolina and S. G. Morgan and G. E. Hanley and T. F. Oberlander and B. Mintzes
DOI: 10.9778/cmajo.20150067
01/2016

Fetal Effects of In Utero Serotonin Reuptake Inhibitor (SRI) Antidepressant Exposure
Fetal Development
Gillian Hanley and Kaia Hookenson and Dan Rurak and Tim F. Oberlander
DOI: 10.1007/978-3-319-22023-9_18
2016

Opportunistic salpingectomy for ovarian cancer prevention
Gynecologic Oncology Research and Practice
Gillian E. Hanley and Jessica N. McAlpine and Janice S. Kwon and Gillian Mitchell
DOI: 10.1186/s40661-015-0014-1
05/2015

Trends and Determinants of Prescription Drug Use during Pregnancy and Postpartum in British Columbia, 2002–2011: A Population-Based Cohort Study
PLOS ONE
Kate Smolina and Gillian E. Hanley and Barbara Mintzes and Tim F. Oberlander and Steve Morgan
DOI: 10.1371/journal.pone.0128312
05/2015

Prenatal exposure to serotonin reuptake inhibitor antidepressants and childhood behavior
Pediatric Research
Gillian E. Hanley and Ursula Brain and Tim F. Oberlander
DOI: 10.1038/pr.2015.77
04/2015

Costs and Benefits of Opportunistic Salpingectomy as an Ovarian Cancer Prevention Strategy
Obstetrics & Gynecology
Janice S. Kwon and Jessica N. McAlpine and Gillian E. Hanley and Sarah J. Finlayson and Trevor Cohen and Dianne M. Miller and C. Blake Gilks and David G. Huntsman
DOI: 10.1097/aog.0000000000000630
02/2015

Prenatal exposure to SSRI antidepressants and anxious behaviours in childhood
International Journal of Developmental Neuroscience
G.E. Hanley and U. Brain and T.F. Oberlander
DOI: 10.1016/j.ijdevneu.2015.04.117
2015

Patterns of psychotropic medicine use in pregnancy in the United States from 2006 to 2011 among women with private insurance
BMC Pregnancy and Childbirth
Gillian E Hanley and Barbara Mintzes
DOI: 10.1186/1471-2393-14-242
07/2014

Opportunistic salpingectomy: uptake, risks, and complications of a regional initiative for ovarian cancer prevention
American Journal of Obstetrics and Gynecology
Jessica N. McAlpine and Gillian E. Hanley and Michelle M.M. Woo and Alicia A. Tone and Nirit Rozenberg and Kenneth D. Swenerton and C. Blake Gilks and Sarah J. Finlayson and David G. Huntsman and Dianne M. Miller
DOI: 10.1016/j.ajog.2014.01.003
05/2014

The effect of perinatal exposures on the infant: Antidepressants and depression
Best Practice & Research Clinical Obstetrics & Gynaecology
Gillian E. Hanley and Tim F. Oberlander
DOI: 10.1016/j.bpobgyn.2013.09.001
01/2014

The impact of maternal positive and negative affect on fetal physiology and diurnal patterns
Israeli Journal of Psychiatry and Related Sciences
PubMed: 25372560
2014

Ethnicity-specific birthweight distributions improve identification of term newborns at risk for short-term morbidity
American Journal of Obstetrics and Gynecology
Gillian E. Hanley and Patricia A. Janssen
DOI: 10.1016/j.ajog.2013.06.042
11/2013

Infant developmental outcomes following prenatal exposure to antidepressants, and maternal depressed mood and positive affect
Early Human Development
Gillian E. Hanley and Ursula Brain and Tim F. Oberlander
DOI: 10.1016/j.earlhumdev.2012.12.012
08/2013

Reply to Klinger et al
Birth Defects Research Part A: Clinical and Molecular Teratology
Gillian E. Hanley and Tim F. Oberlander
DOI: 10.1002/bdra.23095
11/2012

Ethnicity-Specific Growth Distributions for Prediction of Newborn Morbidity
Journal of Obstetrics and Gynaecology Canada
Gillian E. Hanley and Patricia A. Janssen
DOI: 10.1016/s1701-2163(16)35380-4
09/2012

Neurodevelopmental outcomes following prenatal exposure to serotonin reuptake inhibitor antidepressants: A “social teratogen” or moderator of developmental risk?
Birth Defects Research Part A: Clinical and Molecular Teratology
Gillian E. Hanley and Tim F. Oberlander
DOI: 10.1002/bdra.23032
06/2012

Prescription Drug Use in Pregnancy: A Retrospective, Population-Based Study in British Columbia, Canada (2001–2006)
Clinical Therapeutics
Jamie R. Daw and Barbara Mintzes and Michael R. Law and Gillian E. Hanley and Steven G. Morgan
DOI: 10.1016/j.clinthera.2011.11.025
01/2012

Ethnic Disparities in Antipsychotic Drug Use in British Columbia: A Cross-Sectional Retrospective Study
Psychiatric Services
Joseph H. Puyat and Gillian E. Hanley and Colleen M. Cunningham and Michael R. Law and Sabrina T. Wong and Jason M. Sutherland and Steven G. Morgan
DOI: 10.1176/ps.62.9.pss6209_1026
09/2011

The redistributive effect of the move from age-based to income-based prescription drug coverage in British Columbia, Canada
Health Policy
Gillian E. Hanley and Steve Morgan and Morris Barer and Robert J. Reid
DOI: 10.1016/j.healthpol.2010.12.005
07/2011

Prescription drug use during pregnancy in developed countries: a systematic review
Pharmacoepidemiology and Drug Safety
Jamie R. Daw and Gillian E. Hanley and Devon L. Greyson and Steven G. Morgan
DOI: 10.1002/pds.2184
07/2011

Income-Related Inequity in Initiation of Evidence-Based Therapies Among Patients with Acute Myocardial Infarction
Journal of General Internal Medicine
Gillian E. Hanley and Steve Morgan and Robert J. Reid
DOI: 10.1007/s11606-011-1799-1
07/2011

Ethnic differences in the use of prescription drugs in British Columbia: A cross-sectional analysis of linked survey and administrative data
Open Science
PubMed: 21915239
05/2011

Income inequities in end-of-life health care spending in British Columbia, Canada: A cross-sectional analysis, 2004-2006
International Journal for Equity in Health
Colleen M Cunningham and Gillian E Hanley and Steven G Morgan
DOI: 10.1186/1475-9276-10-12
2011

Clinician-Scientists in Canada: Barriers to Career Entry and Progress
PLoS ONE
Bryn Lander and Gillian E. Hanley and Janet Atkinson-Grosjean
DOI: 10.1371/journal.pone.0013168
10/2010

Patterns in the use of benzodiazepines in British Columbia: Examining the impact of increasing research and guideline cautions against long-term use
Health Policy
Colleen M. Cunningham and Gillian E. Hanley and Steve Morgan
DOI: 10.1016/j.healthpol.2010.03.008
10/2010

Registration for public drug benefits across areas of differing ethnic composition in British Columbia, Canada
BMC Health Services Research
Vivian W Leong and Steve Morgan and Sabrina T Wong and Gillian E Hanley and Charlyn Black
DOI: 10.1186/1472-6963-10-171
06/2010

Regional Variation in the Cesarean Delivery and Assisted Vaginal Delivery Rates
Obstetrics & Gynecology
Gillian E. Hanley and Patricia A. Janssen and Devon Greyson
DOI: 10.1097/aog.0b013e3181dd918c
06/2010

Explaining Prescription Drug Use and Expenditures Using the Adjusted Clinical Groups Case-Mix System in the Population of British Columbia, Canada
Medical Care
Gillian E. Hanley and Steve Morgan and Robert J. Reid
DOI: 10.1097/mlr.0b013e3181ca3d5d
05/2010

Individual and Contextual Determinants of Regional Variation in Prescription Drug Use: An Analysis of Administrative Data from British Columbia
PLoS ONE
Steven G. Morgan and Colleen M. Cunningham and Gillian E. Hanley
DOI: 10.1371/journal.pone.0015883
2010

Prescription drug insurance and unmet need for health care
Open Medicine
PubMed: 21603050
09/2009

Comparison of tiered formularies and reference pricing policies: A systematic review
Open Medicine
PubMed: 21603047
08/2009

Open access archiving and article citation within health services and policy research
Journal of Canadian Health Libraries Association
07/2009

Breadth, Depth and Agreement among Provincial Formularies in Canada
Healthcare Policy | Politiques de Santé
Steve Morgan and Gillian Hanley and Colette Raymond and Régis Blais
DOI: 10.12927/hcpol.2009.20685
05/2009

Chronic catastrophes: Exploring the concentration and sustained nature of ambulatory prescription drug expenditures in the population of British Columbia, Canada
Social Science & Medicine
Gillian E. Hanley and Steve Morgan
DOI: 10.1016/j.socscimed.2008.12.008
03/2009

On the validity of area-based income measures to proxy household income
BMC Health Services Research
Gillian E Hanley and Steve Morgan
DOI: 10.1186/1472-6963-8-79
04/2008

Distributional consequences of the transition from age-based to income-based prescription drug coverage in British Columbia, Canada
Health Economics
Gillian E. Hanley and Steve Morgan and Jeremiah Hurley and Eddy van Doorslaer
DOI: 10.1002/hec.1337
2008

Influencing Drug Prices through Formulary-Based Policies: Lessons from New Zealand
Healthcare Policy | Politiques de Santé
Steve Morgan and Gillian Hanley and Meghan McMahon and Morris Barer
DOI: 10.12927/hcpol.2007.19097
08/2007

Income-Based Drug Coverage in British Columbia: Lessons for BC and the Rest of Canada
Healthcare Policy | Politiques de Santé
Steve Morgan and Robert Evans and Gillian Hanley and Patricia Caetano and Charlyn Black
DOI: 10.12927/hcpol.2007.18545
11/2006

Income-Based Drug Coverage in British Columbia: The Impact on the Distribution of Financial Burden
Healthcare Policy | Politiques de Santé
Gillian Hanley and Steve Morgan and Lixiang Yan
DOI: 10.12927/hcpol.2007.18514
11/2006

Research

Prescription drug use during pregnancy
I am examining the safety of using psychotropic medicines during pregnancy—specifically whether using antidepressants during pregnancy may increase a child’s risk for autism spectrum disorder.

Ovarian cancer prevention
I study whether removing a woman’s fallopian tubes at the time of other routine gynecologic surgeries is a safe, effective and cost-effective ovarian cancer prevention strategy. I will also study whether sending all women diagnosed with a certain type of ovarian cancer for genetic testing will help us identify and intervene to prevent future cancers among younger generations of women in British Columbia.

Grants

CIHR Operating Grant - Project: "Developmental origins of autism: A population level linked data study of prenatal antidepressant exposure" (2013-2016)

Canadian Cancer Society Research Institute Grant - Project: "A population-based assessment of an ovarian cancer prevention program" (2014-2017)