Megan Levings
PhD
Investigator, BC Children's Hospital
Director, Childhood Diseases Research Theme
Cytotherapy
Madeline P. Lauener and Marie-Hlne Normand and Tracy Ngo and Sayeh Abdossamadi and Elena Ostroumov and Megan K. Levings and Karen Sherwood and Franz Fenninger and Paul Keown and Mlanie Dieud and Kirk R. Schultz
DOI: 10.1016/j.jcyt.2026.10206205 / 2026
Gastro Hep Advances
Kirsten A. Ward-Hartstonge and Sabine Ivison and Qing Huang and Laura Cook and Brian Bressler and Megan K. Levings and Maria Schmit and Anna Polyvyana and Pedram Tavakoli
DOI: 10.1016/j.gastha.2026.100892Science Advances
Megan K Levings and Matthew Scott Macauley and Susmita Sarkar and Jaesoo Jung and Jhon Ralph Enterina and Som Gowda Nanjappa and Maju Joe and Stacy Alyse Malaker and Jamey David Marth and Kei Takahashi-Yamashiro and Zeinab Jame-Chenarboo and Edward Schmidt and Guilherme Lima and Ratmir Derda and Madeline Crichton and Liany Luna-Dulcey and Sabine Ivison and Chris D. St. Laurent and Sung-Yao Lin and Reni John and Fahima Mozaneh
DOI: 10.1126/sciadv.adz809611 / 2025
Biorxiv
Monajemi, M. and Craciun, A.S. and Huang, Q. and Dai, L. and Mojibian, M. and Crome, S.Q. and Verchere, C.B. and Levings, M.K.
DOI: 10.1101/2025.08.04.668458Cell Reports Medicine
Tuomela, K. and Garcia, R.V. and Boardman, D.A. and Tavakoli, P. and Ancheta-Schmit, M. and Sham, H.P. and Cheng, L. and Struthers, M. and Bressler, B. and Vallance, B.A. and Zhao, Q. and Levings, M.K.
DOI: 10.1016/j.xcrm.2025.102303Molecular Therapy Methods and Clinical Development
Tuomela, K. and Leong, E.S.Y. and Haque, M. and Mangat, S. and Fung, V.C.W. and Garcia, R.V. and Archambault, A.-S. and Boardman, D.A. and Klein Geltink, R.I. and Mojibian, M. and Levings, M.K.
DOI: 10.1016/j.omtm.2025.101600American Journal of Transplantation
Azarfar, G. and Sun, Y. and Pasini, E. and Sidhu, A. and Brudno, M. and Humar, A. and Kumar, D. and Bhat, M. and Ferreira, V.H. and Delisle, J.-S. and Hosseini-Moghaddam, S. and Cardinal, H. and Dieud{\'e}, M. and Racine, N. and Top, K. and DeSerres, G. and West, L. and Cloutier, M. and Bazin, R. and Lemieux, C. and De Serres, S. and Shalhoub, S. and Kabbani, D. and H{\'e}bert, M.-J. and Gongal, P. and Stephens, K. and Belga, S. and Levings, M.K. and Turgeon, J. and Khrifi, Z. and Samson, F. and Desjardins, M. and Brown, H. and Doiron, J. and Baker, C. and Toth, T. and Luke, G. and Pinzon, N. and Hall, V.G. and Robertson, K. and Mangan, H.
DOI: 10.1016/j.ajt.2024.11.033Developmental Cell
Stankiewicz, L.N. and Salim, K. and Flaschner, E.A. and Wang, Y.X. and Edgar, J.M. and Durland, L.J. and Lin, B.Z.B. and Bingham, G.C. and Major, M.C. and Jones, R.D. and Blau, H.M. and Rideout, E.J. and Levings, M.K. and Zandstra, P.W. and Rossi, F.M.V.
DOI: 10.1016/j.devcel.2024.09.011Journal of Clinical Immunology
Lu, H.Y. and Vaseghi-Shanjani, M. and Lam, A.J. and Sharma, M. and Mohajeri, A. and Silva, L.B.R. and Gillies, J. and Yang, G.X. and Lin, S. and Fu, M.P. and Salman, A. and Rahmanian, R. and Armstrong, L. and Halparin, J. and Yang, C.L. and Chilvers, M. and Henkelman, E. and Rehmus, W. and Morrison, D. and Setiadi, A. and Mostafavi, S. and Kobor, M.S. and Kozak, F.K. and Biggs, C.M. and van Karnebeek, C. and Hildebrand, K.J. and Levings, M.K. and Turvey, S.E.
DOI: 10.1007/s10875-025-01882-2Nature Immunology
Bluestone, J.A. and Burnett, B.K. and Crute, C.E. and Fellows, M.D. and Levings, M. and Lebrec, H. and Pereira Mouri{\`e}s, L. and Rice, J. and Rohan, P. and Roncarolo, M.G. and Rotrosen, D.
DOI: 10.1038/s41590-025-02154-2Pediatric Transplantation
Leung, M.L. and Barrett-Chan, E. and Levings, M.K. and Vercauteren, S. and Blydt-Hansen, T.D.
DOI: 10.1111/petr.70041Science Advances
Boardman, D.A. and Mangat, S. and Gillies, J.K. and Leon, L. and Fung, V.C.W. and Haque, M. and Mojibian, M. and Halvorson, T. and Huang, Q. and Tuomela, K. and Wardell, C.M. and Brown, A. and Lam, A.J. and Levings, M.K.
DOI: 10.1126/sciadv.adx7845Biorxiv
Halvorson, T. and Boucher, G. and Yokosawa, D. and Huang, J.Q. and Garcia, R. and Sanderink, L. and Chen, L. and Liu, L. and Fajardo-Despaigne, J.E. and Halvorson, J. and Brinkman, R. and Vercauteren, S. and Lesage, S. and Bramson, J. and Rioux, J.D. and Ivison, S. and Levings, M.K.
DOI: 10.1101/2025.07.15.664847Transplantation
Stark, H. and Ho, Q.Y. and Cross, A. and Alessandrini, A. and Bertaina, A. and Brennan, D. and Busque, S. and Demetris, A. and Devey, L. and Fruhwirth, G. and Fuchs, E. and Friend, P. and Geissler, E. and Guillonneau, C. and Hester, J. and Isaacs, J. and Jaeckel, E. and Kawai, T. and Lakkis, F. and Leventhal, J. and Levings, M. and Levitsky, J. and Lombardi, G. and Martinez-Llordella, M. and Mathew, J. and Moreau, A. and Reinke, P. and Riella, L.V. and Sachs, D. and Fueyo, A.S. and Schreeb, K. and Sykes, M. and Tang, Q. and Thomson, A. and Tree, T. and Trzonkowski, P. and Uchida, K. and Veale, J. and Weiner, J. and Wekerle, T. and Issa, F.
DOI: 10.1097/TP.0000000000005311Transplantation
Filatov, E. and Sasaki, S. and Haque, M. and Kar, S. and Fung, V.C.W. and Mojibian, M. and Krentz, N.A.J. and MacDonald, K.N. and Salim, K. and Soukhatcheva, G. and Dai, D.L. and Orban, P.C. and Verchere, C.B. and Levings, M.K. and Lynn, F.C.
DOI: 10.1097/TP.0000000000005463Immunology and Cell Biology
Rioux, J.D. and Boucher, G. and Forest, A. and Bouchard, B. and Coderre, L. and Daneault, C. and Frayne, I.R. and Legault, J.T. and Bitton, A. and Ananthakrishnan, A. and Lesage, S. and Xavier, R.J. and Des Rosiers, C. and Bitton, A. and Boucher, G. and Charron, G. and Forest, A. and Goyette, P. and Ivison, S. and Joseph, L. and Kohen, R. and Lachaine, J. and Lesage, S. and Levings, M. and Rioux, J.D. and Legault, J.T. and Vachon, L. and Veilleux, S. and White-Guay, B.
DOI: 10.1111/imcb.70039Nature Reviews Drug Discovery
Wardell, C.M. and Boardman, D.A. and Levings, M.K.
DOI: 10.1038/s41573-024-01089-xAmerican Journal of Transplantation
Colpitts, S.J. and Jegatheeswaran, S. and Oakie, A. and Mashhouri, S. and Sachewsky, N. and Murshed, H. and Mathews, J.A. and Reid, K.T. and Misra, P.S. and Fung, V.C.W. and Reichman, T.W. and Nostro, M.C. and Verchere, C.B. and Levings, M.K. and Crome, S.Q.
DOI: 10.1016/j.ajt.2025.05.023Jci Insight
Durgam, S.S. and Rosado-S{\'a}nchez, I. and Yin, D. and Speck, M. and Mojibian, M. and Sayin, I. and Hynes, G.E. and Alegre, M.-L. and Levings, M.K. and Chong, A.S.
DOI: 10.1172/jci.insight.188624Current Opinion in Immunology
Wright, R.C. and Campbell, D.J. and Levings, M.K.
DOI: 10.1016/j.coi.2025.102554Science Translational Medicine
Wardell, C.M. and Fung, V.C.W. and Chen, E. and Haque, M. and Tan, D.F.H. and Leca, M. and Gillies, J. and Spanier, J.A. and Mojibian, M. and Fife, B.T. and Levings, M.K.
DOI: 10.1126/scitranslmed.adp6519ACS Synthetic Biology
Freitas, B.F.A. and Verchere, C.B. and Levings, M.K.
DOI: 10.1021/acssynbio.4c00589Transplantation
Halvorson, T. and Ivison, S. and Huang, Q. and Ladua, G. and Yotis, D.M. and Mannar, D. and Subramaniam, S. and Ferreira, V.H. and Kumar, D. and Belga, S. and Levings, M.K.
DOI: 10.1097/TP.0000000000004873ImmunoHorizons
Ivison, S. and Boucher, G. and Zheng, G. and Garcia, R.V. and Kohen, R. and Bitton, A. and Rioux, J.D. and Levings, M.K. and Charron, G. and Des Rosiers, C. and Forest, A. and Goyette, P. and Joseph, L. and Lachaine, J. and Lesage, S. and Legault, J.T. and Vachon, L. and White-Guay, B. and Veilleux, S.
DOI: 10.4049/immunohorizons.2300095Human Immunology
Ionescu, L.I. and Blydt-Hansen, T. and Foster, B.J. and Allen, U. and Birk, P.E. and Hamiwka, L. and Phan, V. and Min, S. and Ivison, S. and Levings, M. and West, L.J. and Mital, S. and Urschel, S.
DOI: 10.1016/j.humimm.2024.110837Medrxiv
Rioux, J.D. and Boucher, G. and Forest, A. and Bouchard, B. and Coderre, L. and Daneault, C. and Frayne, I.R. and Legault, J.T. and Bitton, A. and Ananthakrishnan, A. and Lesage, S. and Xavier, R.J. and Rosiers, C.D. and Charron, G. and Goyette, P. and Ivison, S. and Joseph, L. and Kohen, R. and Lachaine, J. and Levings, M. and Vachon, L. and Veilleux, S. and White-Guay, B.
DOI: 10.1101/2024.09.19.24314034Biorxiv
Boardman, D.A. and Mangat, S. and Gillies, J.K. and Fung, V.C.W. and Haque, M. and Mojibian, M. and Tuomela, K. and Wardell, C.M. and Brown, A. and Lam, A.J. and Levings, M.K.
DOI: 10.1101/2024.10.01.616177bioRxiv
Wardell, C.M. and Fung, V.C.W. and Chen, E. and Haque, M. and Gillies, J. and Spanier, J.A. and Mojibian, M. and Fife, B.T. and Levings, M.K.
DOI: 10.1101/2024.04.06.588414Biorxiv
Tuomela, K. and Garcia, R.V. and Boardman, D.A. and Tavakoli, P. and Ancheta-Schmit, M. and Sham, H.P. and Cheng, L. and Struthers, M. and Bressler, B. and Vallance, B.A. and Zhao, Q. and Levings, M.K.
DOI: 10.1101/2024.10.01.616157Inflammatory Bowel Diseases
Cook, L. and Wong, M.Q. and Rees, W.D. and Schick, A. and Lisko, D.J. and Lunken, G.R. and Wang, X. and Peters, H. and Oliveira, L. and Lau, T. and Mah, R. and Bressler, B. and Levings, M.K. and Steiner, T.S.
DOI: 10.1093/ibd/izad238Medrxiv
Trang, K.B. and Sharma, P. and Cook, L. and Mount, Z. and Thomas, R.M. and Kulkarni, N.N. and Cabrera, E.C. and Rachimi, S. and Pahl, M.C. and Pippin, J.A. and Su, C. and Kaestner, K.H. and O?Brien, J.M. and Wagley, Y. and Hankenson, K.D. and Jermusyk, A. and Hoskins, J.W. and Amundadottir, L.T. and Xu, M. and Brown, K.M. and Anderson, S.A. and Yang, W. and Titchenell, P.M. and Seale, P. and Zemel, B.S. and Chesi, A. and Romberg, N. and Levings, M.K. and Grant, S.F.A. and Wells, A.D.
DOI: 10.1101/2024.08.12.24311676Nature Medicine
Tatovic, D. and Marwaha, A. and Taylor, P. and Hanna, S.J. and Carter, K. and Cheung, W.Y. and Luzio, S. and Dunseath, G. and Hutchings, H.A. and Holland, G. and Hiles, S. and Fegan, G. and Williams, E. and Yang, J.H.M. and Domingo-Vila, C. and Pollock, E. and Wadud, M. and Ward-Hartstonge, K. and Marques-Jones, S. and Bowen-Morris, J. and Stenson, R. and Levings, M.K. and Gregory, J.W. and Tree, T.I.M. and Dayan, C. and Gevers, E. and Kanumakala, S. and Nair, S. and Gardner, C. and Ajzensztejn, M. and Wei, C. and Mouditis, C. and Campbell, F. and Greening, J. and Webb, E. and Chen, M. and Amin, R. and White, B. and Shetty, A. and Bidder, C. and Conway, N. and Mayo, A. and Christakou, E. and Sychowska, K. and Shahrabi, Y. and Robinson, M. and Ahmed, S. and Dutz, J. and Cook, L.
DOI: 10.1038/s41591-024-03115-2Diabetologia
Tuomela, K. and Levings, M.K.
DOI: 10.1007/s00125-023-06076-2Scientific Reports
Gaultier, G.N. and McMillan, B. and Poloni, C. and Lo, M. and Cai, B. and Zheng, J.J. and Baer, H.M. and Shulha, H.P. and Simmons, K. and Mrquez, A.C. and Bartlett, S.R. and Cook, L. and Levings, M.K. and Steiner, T. and Sekirov, I. and Zlosnik, J.E.A. and Morshed, M. and Skowronski, D.M. and Krajden, M. and Jassem, A.N. and Sadarangani, M.
DOI: 10.1038/s41598-024-59535-0Biorxiv
Durgam, S.S. and Rosado-S{\'a}nchez, I. and Yin, D. and Speck, M. and Mojibian, M. and Sayin, I. and Hynes, G.E. and Alegre, M.L. and Levings, M.K. and Chong, A.S.
DOI: 10.1101/2024.09.20.614149Biorxiv
Jones, R.D. and Salim, K. and Stankiewicz, L.N. and Edgar, J.M. and Leon, L. and Gillies, J.K. and Murtaza, A. and Durland, L.J. and Raval, D. and Taberna, T.P. and Hsu, H.H. and Zimmerman, C. and Michaels, Y.S. and Rossi, F.M.V. and Levings, M.K. and Zandstra, P.W.
DOI: 10.1101/2024.10.29.620998Research Square
Gaultier, G.N. and McMillan, B. and Poloni, C. and Lo, M. and Cai, B. and Zheng, J.J. and Baer, H.M. and Shulha, H. and Simmons, K. and Mrquez, A.C. and Bartlett, S.R. and Cook, L. and Levings, M.K. and Steiner, T. and Sekirov, I. and Zlosnik, J.E.A. and Morshed, M. and Skowronski, D.M. and Krajden, M. and Jassem, A.N. and Sadarangani, M.
DOI: 10.21203/rs.3.rs-3214357Proceedings of the National Academy of Sciences of the United States of America
Lamarche, C. and Ward-Hartstonge, K. and Mi, T. and Lin, D.T.S. and Huang, Q. and Brown, A. and Edwards, K. and Novakovsky, G.E. and Qi, C.N. and Kobor, M.S. and Zebley, C.C. and Weber, E.W. and Mackall, C.L. and Levings, M.K.
DOI: 10.1073/pnas.2219086120Transplantation
Ellis, C.E. and Mojibian, M. and Ida, S. and Fung, V.C.W. and Skovs?, S?. and McIver, E. and O'Dwyer, S. and Webber, T.D. and Braam, M.J.S. and Saber, N. and Sasaki, S. and Lynn, F.C. and Kieffer, T.J. and Levings, M.K.
DOI: 10.1097/TP.0000000000004709Endocrine Reviews
Ramzy, A. and Belmonte, P.J. and Braam, M.J.S. and Ida, S. and Wilts, E.M. and Levings, M.K. and Rezania, A. and Kieffer, T.J.
DOI: 10.1210/endrev/bnac021European Journal of Immunology
Halvorson, T. and Tuomela, K. and Levings, M.K.
DOI: 10.1002/eji.202250002Frontiers in Immunology
Colpitts, S.J. and Budd, M.A. and Monajemi, M. and Reid, K.T. and Murphy, J.M. and Ivison, S. and Verchere, C.B. and Levings, M.K. and Crome, S.Q.
DOI: 10.3389/fimmu.2023.1107582Journal of Autoimmunity
Boardman, D.A. and Wong, M.Q. and Rees, W.D. and Wu, D. and Himmel, M.E. and Orban, P.C. and Vent-Schmidt, J. and Zachos, N.C. and Steiner, T.S. and Levings, M.K.
DOI: 10.1016/j.jaut.2022.102961Medrxiv
Trang, K.B. and Pahl, M.C. and Pippin, J.A. and Su, C. and Littleton, S.H. and Sharma, P. and Kulkarni, N.N. and Ghanem, L.R. and Terry, N.A. and O?Brien, J.M. and Wagley, Y. and Hankenson, K.D. and Jermusyk, A. and Hoskins, J.W. and Amundadottir, L.T. and Xu, M. and Brown, K.M. and Anderson, S.A. and Yang, W. and Titchenell, P.M. and Seale, P. and Cook, L. and Levings, M.K. and Zemel, B.S. and Chesi, A. and Wells, A.D. and Grant, S.F.A.
DOI: 10.1101/2023.08.30.23294092Immunology and Cell Biology
Poloni, C. and Schonhofer, C. and Ivison, S. and Levings, M.K. and Steiner, T.S. and Cook, L.
DOI: 10.1111/imcb.12636Transplantation
Kim, J.-Y.V. and Assadian, S. and Hollander, Z. and Burns, P. and Shannon, C.P. and Lam, K. and Toma, M. and Ignaszewski, A. and Davies, R.A. and Delgado, D. and Haddad, H. and Isaac, D. and Kim, D. and Mui, A. and Rajda, M. and West, L. and White, M. and Zieroth, S. and Keown, P.A. and McMaster, W.R. and Ng, R.T. and McManus, B.M. and Levings, M.K. and Tebbutt, S.J.
DOI: 10.1097/TP.0000000000004607The Journal of experimental medicine
Bernaldo-de-Quirs, E. and Camino, M. and Martnez-Bonet, M. and Gil-Jaurena, J.M. and Gil, N. and Hernndez-Flrez, D. and Fernndez-Santos, M.E. and Butragueo, L. and Dijke, I.E. and Levings, M.K. and West, L.J. and Pion, M. and Correa-Rocha, R.
DOI: 10.1084/jem.20231045American Journal of Transplantation
Haque, M. and Boardman, D.A. and Levings, M.K.
DOI: 10.1016/j.ajt.2023.04.010Clinical Infectious Diseases
Ferreira, V.H. and Ierullo, M. and Mavandadnejad, F. and Kurtesi, A. and Hu, Q. and Hardy, W.R. and Hall, V.G. and Pinzon, N. and Yotis, D. and Gingras, A.-C. and Belga, S. and Shalhoub, S. and Hbert, M.-J. and Humar, A. and Kabbani, D. and Kumar, D. and Delisle, J.-S. and Hosseini-Moghaddam, S. and Cardinal, H. and Dieud, M. and Racine, N. and Top, K. and DeSerres, G. and West, L. and Levings, M. and Cloutier, M. and Bazin, R. and Lemieux, C. and De Serres, S. and Gongal, P. and Stephens, K. and Turgeon, J. and Khrifi, Z. and Samson, F. and Desjardins, T.M. and Brown, T.H. and Doiron, T.J. and Ladua, T.G. and Baker, C. and Toth, T. and Luke, G. and Robertson, K. and Mangan, H.
DOI: 10.1093/cid/ciad175bioRxiv
Ellis, C.E. and Mojibian, M. and Ida, S. and Fung, V.C.W. and Skovs?, S. and McIver, E. and O'Dwyer, S. and Webber, T.D. and Braam, M.J.S. and Saber, N. and Kieffer, T.J. and Levings, M.K.
DOI: 10.1101/2023.02.23.529741Immunological Reviews
Tuomela, K. and Salim, K. and Levings, M.K.
DOI: 10.1111/imr.13254The Journal of clinical investigation
Spanier, J.A. and Fung, V. and Wardell, C.M. and Alkhatib, M.H. and Chen, Y. and Swanson, L.A. and Dwyer, A.J. and Weno, M.E. and Silva, N. and Mitchell, J.S. and Orban, P.C. and Mojibian, M. and Verchere, C.B. and Fife, B.T. and Levings, M.K.
DOI: 10.1172/JCI168601medRxiv
Halvorson, T. and Ivison, S. and Huang, Q. and Ladua, G. and Yotis, D.M. and Mannar, D. and Subramaniam, S. and Ferreira, V.H. and Kumar, D. and Belga, S. and Levings, M.K. and Delisle, J.-S. and Hosseini-Moghaddam, S. and Cardinal, H. and Dieud, M. and Racine, N. and Top, K. and DeSerres, G. and West, L. and Cloutier, M. and Bazin, R. and Lemieux, C. and De Serres, S. and Humar, A. and Shalhoub, S. and Kabbani, D. and Hbert, M.-J. and Gongal, P. and Stephens, K. and Turgeon, J. and Khrifi, Z. and Samson, F. and Desjardins, M. and Brown, H. and Doiron, J. and Baker, C. and Toth, T. and Luke, G. and Pinzon, N. and Hall, V.G. and Robertson, K. and Mangan, H.
DOI: 10.1101/2023.08.14.23293991bioRxiv
Spanier, J.A. and Fung, V. and Wardell, C.M. and Alkhatib, M.H. and Chen, Y. and Swanson, L.A. and Dwyer, A.J. and Weno, M.E. and Silva, N. and Mitchell, J.S. and Orban, P.C. and Mojibian, M. and Verchere, C.B. and Fife, B.T. and Levings, M.K.
DOI: 10.1101/2023.02.23.529737JCI Insight
Rosado-Snchez, I. and Haque, M. and Salim, K. and Speck, M. and Fung, V.C.W. and Boardman, D.A. and Mojibian, M. and Raimondi, G. and Levings, M.K.
DOI: 10.1172/jci.insight.167215bioRxiv
Stankiewicz, L.N. and Salim, K. and Flaschner, E.A. and Wang, Y.X. and Edgar, J.M. and Lin, B.Z.B. and Bingham, G.C. and Major, M.C. and Jones, R.D. and Blau, H.M. and Rideout, E.J. and Levings, M.K. and Zandstra, P.W. and Rossi, F.M.V.
DOI: 10.1101/2023.04.13.536804Gene Therapy
Proics, E. and David, M. and Mojibian, M. and Speck, M. and Lounnas-Mourey, N. and Govehovitch, A. and Baghdadi, W. and Desnouveaux, J. and Bastian, H. and Freschi, L. and Privat, G. and Pouzet, C. and Grossi, M. and Heimendinger, P. and Abel, T. and Fenard, D. and Levings, M.K. and Meyer, F. and Dumont, C.
DOI: 10.1038/s41434-022-00358-xHaematologica
Lauener, M.P. and AzadPour, S. and Abdossamadi, S. and Parthasarathy, V. and Ng, B. and Ostroumov, E. and Cuvelier, G.D.E. and Levings, M.K. and MacDonald, K.N. and Kariminia, A. and Schultz, K.R.
DOI: 10.3324/haematol.2022.280653European Journal of Immunology
Tuomela, K. and Levings, M.K.
DOI: 10.1002/eji.202350511Immunotherapy Advances
Marwaha, A.K. and Chow, S. and Pesenacker, A.M. and Cook, L. and Sun, A. and Long, S.A. and Yang, J.H.M. and Ward-Hartstonge, K.A. and Williams, E. and Domingo-Vila, C. and Halani, K. and Harris, K.M. and Tree, T.I.M. and Levings, M.K. and Elliott, T. and Tan, R. and Dutz, J.P.
DOI: 10.1093/immadv/ltab022Journal of Allergy and Clinical Immunology
Boardman, D.A. and Levings, M.K.
DOI: 10.1016/j.jaci.2021.11.007Bio-protocol
Haque, M. and Boardman, D.A. and Lam, A.J. and MacDonald, K.N. and Sanderink, L. and Huang, Q. and Fung, V.C.W. and Ivison, S. and Mojibian, M. and Levings, M.K.
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DOI: 10.1097/txd.000000000000051102 / 2015
Cell Transplantation
Montane, J. and Obach, M. and Alvarez, S. and Bischoff, L. and Dai, D.L. and Soukhatcheva, G. and Priatel, J.J. and Hardenberg, G. and Levings, M.K. and Tan, R. and Orban, P.C. and Verchere, C.B.
DOI: 10.3727/096368914X685249Journal of Immunology
Yao, Y. and Vent-Schmidt, J. and McGeough, M.D. and Wong, M. and Hoffman, H.M. and Steiner, T.S. and Levings, M.K.
DOI: 10.4049/jimmunol.1403225Frontiers in Immunology
Hoeppli, R.E. and Wu, D. and Cook, L. and Levings, M.K.
DOI: 10.3389/fimmu.2015.00061Journal of Immunology
Han, J.M. and Wu, D. and Denroche, H.C. and Yao, Y. and Verchere, C.B. and Levings, M.K.
DOI: 10.4049/jimmunol.1500020Journal of Allergy and Clinical Immunology
Macdonald, K.G. and Dawson, N.A.J. and Huang, Q. and Dunne, J.V. and Levings, M.K. and Broady, R.
DOI: 10.1016/j.jaci.2014.12.1932European Journal of Immunology
Pesenacker, A.M. and Broady, R. and Levings, M.K.
DOI: 10.1002/eji.201344205International Reviews of Immunology
Vent-Schmidt, J. and Han, J.M. and Macdonald, K.G. and Levings, M.K.
DOI: 10.3109/08830185.2013.811657Journal of Immunology
Han, J.M. and Patterson, S.J. and Speck, M. and Ehses, J.A. and Levings, M.K.
DOI: 10.4049/jimmunol.1302181Journal of Clinical Investigation
Antignano, F. and Burrows, K. and Hughes, M.R. and Han, J.M. and Kron, K.J. and Penrod, N.M. and Oudhoff, M.J. and Wang, S.K.H. and Min, P.H. and Gold, M.J. and Chenery, A.L. and Braam, M.J.S. and Fung, T.C. and Rossi, F.M.V. and McNagny, K.M. and Arrowsmith, C.H. and Lupien, M. and Levings, M.K. and Zaph, C.
DOI: 10.1172/JCI69592Cytotherapy
T.D. Prestidge and J.H. Davis and J. Huang and M. Himmel and M. Levings
DOI: 10.1016/j.jcyt.2013.01.16104 / 2013
Cytotherapy
E. Dijke and M. Levings and A. McMurchy and I. Larsen and I. Rebeyka and D. Ross and L. West
DOI: 10.1016/j.jcyt.2013.01.16004 / 2013
Methods in Molecular Biology
McMurchy, A.N. and Levings, M.K.
DOI: 10.1007/978-1-62703-128-8-8Frontiers in Immunology
Broady Raewyn and Huang Qing and MacDonald Katherine and Dunne James and Levings Megan
DOI: 10.3389/conf.fimmu.2013.02.01011Journal of Immunology
Jonathan M, H. and Levings, M.K.
DOI: 10.4049/jimmunol.1301035Journal of Immunology
Himmel, M.E. and MacDonald, K.G. and Garcia, R.V. and Steiner, T.S. and Levings, M.K.
DOI: 10.4049/jimmunol.1201379Frontiers in Immunology
Han Jonathan and Patterson Scott and Ehses Jan and Levings Megan
DOI: 10.3389/conf.fimmu.2013.02.00587PLoS ONE
Yu, R. and Broady, R. and Huang, Y. and Wang, Y. and Yu, J. and Gao, M. and Levings, M. and Wei, S. and Zhang, S. and Xu, A. and Su, M. and Dutz, J. and Zhang, X. and Zhou, Y.
DOI: 10.1371/annotation/fbf9e317-e3ab-4f9a-b317-3de6abff890fBlood
McMurchy, A.N. and Gillies, J. and Gizzi, M.C. and Riba, M. and Garcia-Manteiga, J.M. and Cittaro, D. and Lazarevic, D. and Di Nunzio, S. and Piras, I.S. and Bulfone, A. and Roncarolo, M.G. and Stupka, E. and Bacchetta, R. and Levings, M.K.
DOI: 10.1182/blood-2012-05-431023Journal of Immunology
MacDonald, K.G. and Han, J.M. and Himmel, M.E. and Huang, Q. and Kan, B. and Campbell, A.I.M. and Lavoie, P.M. and Levings, M.K.
DOI: 10.4049/jimmunol.1390019Transplantation Journal
E. Dijke and A. McMurchy and M. Levings and I. Larsen and I. Rebeyka and D. Ross and L. West
DOI: 10.1097/00007890-201211271-0236811 / 2012
Canadian Journal of Diabetes
Joel Montane and Merce Obach and Loraine Bischoff and Galina Soukhatcheva and Paul C. Orban and Gijs Hardenberg and Megan K. Levings and Rusung Tan and C. Bruce Verchere
DOI: 10.1016/j.jcjd.2012.07.46810 / 2012
European Journal of Immunology
Yao, Y. and Levings, M.K. and Steiner, T.S.
DOI: 10.1002/eji.201142213Frontiers in Immunology
Marwaha, A.K. and Leung, N.J. and McMurchy, A.N. and Levings, M.K.
DOI: 10.3389/fimmu.2012.00129Current Opinion in Organ Transplantation
MacDonald, K.G. and Orban, P.C. and Levings, M.K.
DOI: 10.1097/MOT.0b013e328355aaafEuropean Journal of Immunology
Mcmurchy, A.N. and Levings, M.K.
DOI: 10.1002/eji.201141651Plos One
Yurchenko, E. and Shio, M.T. and Huang, T.C. and da Silva Martins, M. and Szyf, M. and Levings, M.K. and Olivier, M. and Piccirillo, C.A.
DOI: 10.1371/journal.pone.0035572American Journal of Physiology Gastrointestinal and Liver Physiology
Ryz, N.R. and Patterson, S.J. and Zhang, Y. and Ma, C. and Huang, T. and Bhinder, G. and Wu, X. and Chan, J. and Glesby, A. and Sham, H.P. and Dutz, J.P. and Levings, M.K. and Jacobson, K. and Vallance, B.A.
DOI: 10.1152/ajpgi.00320.2012Inflammatory Bowel Diseases
Hardenberg, G. and Yao, Y. and Piccirillo, C.A. and Levings, M.K. and Steiner, T.S.
DOI: 10.1002/ibd.21738Frontiers in Immunology
Jonathan M. Han and Scott J. Patterson and Megan K. Levings
DOI: 10.3389/fimmu.2012.00245PLoS ONE
Yu, R. and Broady, R. and Huang, Y. and Wang, Y. and Yu, J. and Gao, M. and Levings, M. and Wei, S. and Zhang, S. and Xu, A. and Su, M. and Dutz, J. and Zhang, X. and Zhou, Y.
DOI: 10.1371/journal.pone.0051040Immunology
Himmel, M.E. and Yao, Y. and Orban, P.C. and Steiner, T.S. and Levings, M.K.
DOI: 10.1111/j.1365-2567.2012.03572.xEuropean Journal of Immunology
Yurchenko, E. and Levings, M.K. and Piccirillo, C.A.
DOI: 10.1002/eji.201141814Cytotherapy
Zhang, X. and De Chickera, S.N. and Willert, C. and Economopoulos, V. and Noad, J. and Rohani, R. and Wang, A.Y. and Levings, M.K. and Scheid, E. and Foley, R. and Foster, P.J. and Dekaban, G.A.
DOI: 10.3109/14653249.2011.605349PLoS ONE
Antignano, F. and Hamilton, M. and Patterson, S. and Ho, V. and Cohen, C. and Levings, M.K. and Krystal, G.
DOI: 10.1371/journal.pone.0021893Seminars in Immunology
McMurchy, A.N. and Bushell, A. and Levings, M.K. and Wood, K.J.
DOI: 10.1016/j.smim.2011.04.001European Journal of Immunology
Himmel, M.E. and Crome, S.Q. and Ivison, S. and Piccirillo, C. and Steiner, T.S. and Levings, M.K.
DOI: 10.1002/eji.201040459Journal of Clinical Investigation
Montane, J. and Bischoff, L. and Soukhatcheva, G. and Dai, D.L. and Hardenberg, G. and Levings, M.K. and Orban, P.C. and Kieffer, T.J. and Tan, R. and Verchere, C.B.
DOI: 10.1172/JCI43048Cancer Immunology, Immunotherapy
Wang, A.Y. and Crome, S.Q. and Jenkins, K.M. and Medin, J.A. and Bramson, J.L. and Levings, M.K.
DOI: 10.1007/s00262-010-0948-4Experimental and Applied Immunotherapy
Wang, A.Y. and Levings, M.K.
DOI: 10.1007/978-1-60761-980-2_10Journal of Immunology
Cohen, C.J. and Crome, S.Q. and MacDonald, K.G. and Dai, E.L. and Mager, D.L. and Levings, M.K.
DOI: 10.4049/jimmunol.1101058Seminars in Immunology
Hardenberg, G. and Steiner, T.S. and Levings, M.K.
DOI: 10.1016/j.smim.2011.01.012Journal of Immunology
Patterson, S.J. and Han, J.M. and Garcia, R. and Assi, K. and Gao, T. and O'Neill, A. and Newton, A.C. and Levings, M.K.
DOI: 10.4049/jimmunol.1002126Inflammatory Bowel Diseases
Ivison, S.M. and Himmel, M.E. and Mayer, M. and Yao, Y. and Kifayet, A. and Levings, M.K. and Steiner, T.S.
DOI: 10.1002/ibd.21428BMC Immunology
Assi, K. and Patterson, S. and Dedhar, S. and Owen, D. and Levings, M. and Salh, B.
DOI: 10.1186/1471-2172-12-42Clinical Immunology
Sarah Crome and Breanna Clive and Adele Wang and Christine Kang and Vickie Chow and Jessie Yiu and Raewyn Broady and Megan Levings
DOI: 10.1016/j.clim.2010.03.36101 / 2010
Clinical Immunology
Scott Patterson and Rosa Garcia and Audrey O'Neill and Tianyan Gao and Alexandra Newton and Megan Levings
DOI: 10.1016/j.clim.2010.03.02501 / 2010
Clinical Immunology
Ashish Sharma and Mihoko Whalen and Qing Huang and Adele Wang and Lixin Xu and Indira Genowati and Meghan Levings and Pascal Lavoie
DOI: 10.1016/j.clim.2010.03.15101 / 2010
Clinical Immunology
Ashish Marwaha and Megan Levings and Sarah Crome and Constadina Panagiotopoulos and John Priatel and Rusung Tan
DOI: 10.1016/j.clim.2010.03.39801 / 2010
European Journal of Immunology
Maggi, L. and Santarlasci, V. and Capone, M. and Peired, A. and Frosali, F. and Crome, S.Q. and Querci, V. and Fambrini, M. and Liotta, F. and Levings, M.K. and Maggi, E. and Cosmi, L. and Romagnani, S. and Annunziato, F.
DOI: 10.1002/eji.200940257Inflammatory Bowel Diseases
Ivison, S.M. and Himmel, M.E. and Hardenberg, G. and Wark, P.A.J. and Kifayet, A. and Levings, M.K. and Steiner, T.S.
DOI: 10.1002/ibd.21097Micron
Abraham, T. and Allan, S.E. and Levings, M.K.
DOI: 10.1016/j.micron.2010.03.005Journal of Allergy and Clinical Immunology
Mcmurchy, A.N. and Gillies, J. and Allan, S.E. and Passerini, L. and Gambineri, E. and Roncarolo, M.G. and Bacchetta, R. and Levings, M.K.
DOI: 10.1016/j.jaci.2010.09.001Immunology
Ladd, M. and Sharma, A. and Huang, Q. and Wang, A.Y. and Xu, L. and Genowati, I. and Levings, M.K. and Lavoie, P.M.
DOI: 10.1111/j.1365-2567.2010.03304.xBlood
Broady, R. and Yu, J. and Chow, V. and Tantiworawit, A. and Kang, C. and Berg, K. and Martinka, M. and Ghoreishi, M. and Dutz, J. and Levings, M.K.
DOI: 10.1182/blood-2010-07-295436Journal of Immunology
Marwaha, A.K. and Crome, S.Q. and Panagiotopoulos, C. and Berg, K.B. and Qin, H. and Ouyang, Q. and Xu, L. and Priatel, J.J. and Levings, M.K. and Tan, R.
DOI: 10.4049/jimmunol.1001860Clinical and Experimental Immunology
Crome, S.Q. and Wang, A.Y. and Levings, M.K.
DOI: 10.1111/j.1365-2249.2009.04037.xJournal of Immunology
Crome, S.Q. and Clive, B. and Wang, A.Y. and Kang, C.Y. and Chow, V. and Yu, J. and Lai, A. and Ghahary, A. and Broady, R. and Levings, M.K.
DOI: 10.4049/jimmunol.1000557Journal of Immunology
Silverman, J.M. and Clos, J. and Horakova, E. and Wang, A.Y. and Wiesgigl, M. and Kelly, I. and Lynn, M.A. and McMaster, W.R. and Foster, L.J. and Levings, M.K. and Reiner, N.E.
DOI: 10.4049/jimmunol.1000541Advances in experimental medicine and biology
McMurchy AN and Di Nunzio S and Roncarolo MG and Bacchetta R and Levings MK
PubMed: 2042941401 / 2009
Blood
Broady, R. and Yu, J. and Levings, M.K.
DOI: 10.1182/blood-2009-04-214437Journal of Immunology
Locke, N.R. and Patterson, S.J. and Hamilton, M.J. and Sly, L.M. and Krystal, G. and Levings, M.K.
DOI: 10.4049/jimmunol.0803749Immunotherapy
McMurchy, A.N. and Levings, M.K.
DOI: 10.2217/IMT.09.33Blood
Di Nunzio, S. and Cecconi, M. and Passerini, L. and McMurchy, A.N. and Baron, U. and Turbachova, I. and Vignola, S. and Valencic, E. and Tommasini, A. and Junker, A. and Cazzola, G. and Olek, S. and Levings, M.K. and Perroni, L. and Roncarolo, M.G. and Bacchetta, R.
DOI: 10.1182/blood-2009-04-214593Advances in Experimental Medicine and Biology
McMurchy, A.N. and Di Nunzio, S. and Roncarolo, M.G. and Bacchetta, R. and Levings, M.K.
DOI: 10.1007/978-1-4419-1599-3_3Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Abraham, T. and Allanb, S.E. and Levings, M.K.
DOI: 10.1117/12.808049European Journal of Immunology
Crome, S.Q. and Wang, A.Y. and Kang, C.Y. and Levings, M.K.
DOI: 10.1002/eji.200838908American Journal of Transplantation
Levings, M.K. and Thomson, A.W.
DOI: 10.1111/j.1600-6143.2009.02810.xClinical Immunology
Rosa Bacchetta and Sara Di Nunzio and Lucia Beatrice Perroni and Laura Passerini and Sarah Allan and Alicia Alstad and Anne Junker and Megan Levings and Maria Grazia Roncarolo
DOI: 10.1016/j.clim.2008.03.18701 / 2008
Clinical Immunology
Sarah Crome and Adele Wang and Megan Levings
DOI: 10.1016/j.clim.2008.03.04301 / 2008
Immunological Reviews
Allan, S.E. and Broady, R. and Gregori, S. and Himmel, M.E. and Locke, N. and Roncarolo, M.G. and Bacchetta, R. and Levings, M.K.
DOI: 10.1111/j.1600-065X.2008.00634.xJournal of Clinical Apheresis
Broady, R. and Yu, J. and Levings, M.K.
DOI: 10.1002/jca.20162International Immunology
Passerini, L. and Allan, S.E. and Battaglia, M. and Di Nunzio, S. and Alstad, A.N. and Levings, M.K. and Roncarolo, M.G. and Bacchetta, R.
DOI: 10.1093/intimm/dxn002Molecular Therapy
Allan, S.E. and Alstad, A.N. and Merindol, N. and Crellin, N.K. and Amendola, M. and Bacchetta, R. and Naldini, L. and Roncarolo, M.G. and Soudeyns, H. and Levings, M.K.
DOI: 10.1038/sj.mt.6300341Regulatory T Cells and Clinical Application
Natasha R. Locke and Natasha K. Crellin and Megan K. Levings
DOI: 10.1007/978-0-387-77909-6_8Nature Medicine
Broady, R. and Levings, M.K.
DOI: 10.1038/nm1108-1155European Journal of Immunology
Allan, S.E. and Song-Zhao, G.X. and Abraham, T. and McMurchy, A.N. and Levings, M.K.
DOI: 10.1002/eji.200838373Immunology
Himmel, M.E. and Hardenberg, G. and Piccirillo, C.A. and Steiner, T.S. and Levings, M.K.
DOI: 10.1111/j.1365-2567.2008.02939.xCytokine
Sarah Q. Crome and Adele Wang and Megan K. Levings
DOI: 10.1016/j.cyto.2007.07.03207 / 2007
Blood
Crellin, N.K. and Garcia, R.V. and Levings, M.K.
DOI: 10.1182/blood-2006-07-035279Journal of Immunological Methods
Crellin, N.K. and Garcia, R.V. and Levings, M.K.
DOI: 10.1016/j.jim.2007.05.008International Immunology
Allan, S.E. and Crome, S.Q. and Crellin, N.K. and Passerini, L. and Steiner, T.S. and Bacchetta, R. and Roncarolo, M.G. and Levings, M.K.
DOI: 10.1093/intimm/dxm014Methods in Molecular Biology
Gregori, S. and Bacchetta, R. and Passerini, L. and Levings, M.K. and Roncarolo, M.G.
DOI: 10.1385/1-59745-395-1:83Clinical Immunology
Rosa Bacchetta and Laura Passerini and Eleonora Gambineri and Sarah Allan and Lucia Perroni and Susan Matthes-Martin and Anita Lawitschka and Steven Ziegler and Megan Levings and Maria Grazia Roncarolo
DOI: 10.1016/j.clim.2006.04.19601 / 2006
Clinical Immunology
Natasha Crellin and Rosa Garcia and Megan Levings
DOI: 10.1016/j.clim.2006.04.00901 / 2006
Clinical Immunology
Sarah Allan and Laura Passerini and Rosa Bacchetta and Mario Amendola and Luigi Naldini and Maria Grazia Roncarolo and Megan Levings
DOI: 10.1016/j.clim.2006.04.52501 / 2006
Immunological Reviews
Roncarolo, M.G. and Gregori, S. and Battaglia, M. and Bacchetta, R. and Fleischhauer, K. and Levings, M.K.
DOI: 10.1111/j.0105-2896.2006.00420.xJournal of Immunology
Gianfrani, C. and Levings, M.K. and Sartirana, C. and Mazzarella, G. and Barba, G. and Zanzi, D. and Camarca, A. and Iaquinto, G. and Giardullo, N. and Auricchio, S. and Troncone, R. and Roncarolo, M.-G.
DOI: 10.4049/jimmunol.177.6.4178Immunological Reviews
Roncarolo, M.G. and Gregori, S. and Battaglia, M. and Bacchetta, R. and Fleischhauer, K. and Levings, M.K.
DOI: 10.1111/j.1600-065X.2006.00448.xJournal of Clinical Investigation
Bacchetta, R. and Passerini, L. and Gambineri, E. and Dai, M. and Allan, S.E. and Perroni, L. and Dagna-Bricarelli, F. and Sartirana, C. and Matthes-Martin, S. and Lawitschka, A. and Azzari, C. and Ziegler, S.F. and Levings, M.K. and Roncarolo, M.G.
DOI: 10.1172/JCI25112Advances in Immunology
Levings, M.K. and Allan, S. and d'Hennezel, E. and Piccirillo, C.A.
DOI: 10.1016/S0065-2776(06)92003-3Journal of Clinical Investigation
Allan, S.E. and Passerini, L. and Bacchetta, R. and Crellin, N. and Dai, M. and Orban, P.C. and Ziegler, S.F. and Roncarolo, M.G. and Levings, M.K.
DOI: 10.1172/JCI24685Gut
Salveti, V.M. and Mazzarella, G. and Gianfrani, C. and Levings, M.K. and Stefanile, R. and De Giulio, B. and Iaquinto, G. and Giardullo, N. and Auricchio, S. and Roncarolo, M.G. and Troncone, R.
DOI: 10.1136/gut.2003.023150Blood
Levings, M.K. and Gregori, S. and Tresoldi, E. and Cazzaniga, S. and Bonini, C. and Roncarolo, M.G.
DOI: 10.1182/blood-2004-03-1211Current Topics in Microbiology and Immunology
Levings, M.K. and Roncarolo, M.G.
DOI: 10.1007/3-540-27702-1_14Journal of Immunology
Crellin, N.K. and Garcia, R.V. and Hadisfar, O. and Allan, S.E. and Steiner, T.S. and Levings, M.K.
DOI: 10.4049/jimmunol.175.12.8051Clinical Genetics
Paul C Orban and Megan K Levings
DOI: 10.1034/j.1399-0004.2003.t01-2-00121.x06 / 2003
Clinical Genetics
Liam R Brunham and Edmond YW Chan and Paul C Orban and Megan K Levings
DOI: 10.1034/j.1399-0004.2003.00121.x06 / 2003
Novartis Foundation Symposium
Roncarolo, M.G. and Gregori, S. and Levings, M. and Bluestone and Shevach and Hafler
International archives of allergy and immunology
Levings, M.K. and Bacchetta, R. and Schulz, U. and Roncarolo, M.G.
DOI: 10.1159/000067596Journal of Experimental Medicine
Levings, M.K. and Sangregorio, R. and Sartirana, C. and Moschin, A.L. and Battaglia, M. and Orban, P.C. and Roncarolo, M.-G.
DOI: 10.1084/jem.20021139European Journal of Immunology
Bacchetta, R. and Sartirana, C. and Levings, M.K. and Bordignon, C. and Narula, S. and Roncarolo, M.-G.
DOI: 10.1002/1521-4141(200208)32:8u003C2237::AID-IMMU2237u003E3.0.CO;2-2Journal of Experimental Medicine
Levings, M.K. and Sangregorio, R. and Roncarolo, M.-G.
DOI: 10.1084/jem.193.11.1295Immunological Reviews
Roncarolo, M.G. and Bacchetta, R. and Bordignon, C. and Narula, S. and Levings, M.K.
DOI: 10.1034/j.1600-065X.2001.1820105.xJournal of Immunology
Levings, M.K. and Sangregorio, R. and Galbiati, F. and Squadrone, S. and De Waal Malefyt, R. and Roncarolo, M.-G.
DOI: 10.4049/jimmunol.166.9.5530Journal of Experimental Medicine
Roncarolo, M.-G. and Levings, M.K. and Traversari, C.
DOI: 10.1084/jem.193.2.f5Journal of Allergy and Clinical Immunology
Levings, M.K. and Roncarolo, M.-G.
DOI: 10.1067/mai.2000.106635Current Opinion in Immunology
Roncarolo, M.-G. and Levings, M.K.
DOI: 10.1016/S0952-7915(00)00162-XBlood
Levings, M.K. and Bessette, D.C. and Schrader, J.W.
DOI: 10.1182/blood.v93.11.3694Blood
Orban, P.C. and Levings, M.K. and Schrader, J.W.
DOI: 10.1182/blood.v94.5.1614.417k22_1614_1622Journal of Immunology
Levings, M.K. and Schrader, J.W.
Experimental Hematology
Levings, M.K.
Journal of Biological Chemistry
Welham, M.J. and Bone, H. and Levings, M. and Learmonth, L. and Wang, L.-M. and Leslie, K.B. and Pierce, J.H. and Schrader, J.W.
DOI: 10.1074/jbc.272.2.1377Generation and Effector Functions of Regulatory Lymphocytes
Maria Grazia Roncarolo and Silvia Gregori and Megan Levings
DOI: 10.1002/0470871628.ch9• Engineering Tregs to tailor their antigen specificity and function
• Developing methods to use Tregs as a cellular therapy in transplantation
• Studying unique cell-signaling pathways in human and mouse Tregs
• Developing biomakers to track Treg function
• Studying the interaction between Tregs and IL-17-producing cells
• Studying tissue-derived Tregs in health versus disease
1. Helmsley Trust: Engineering antigen-specific regulatory T cells for use in type 1 diabetes: Phase 3 (2024)
2. CIHR: Use of CAR Tregs to induce transplantation tolerance (2023)
3. US Dept of Defense: Engineering an effective CAR Treg combination therapy to control VCA rejection (2023)
4. Stem Cell Network: Genetic engineering of hESC-derived insulin-producing cells to improve graft outcomes in type 1 diabetes (2023)
5. CIHR Team Grant: Immunometabolism in diabetes: Harnessing metabolic crosstalk between islets and immune cells for therapy (2022)
6. Stem Cell Network: Clinical trial of the first gene-edited cell replacement therapy for type 1 diabetes (2022)
7. Public Health Agency of Canada: Understanding Immune Responses to SARS-CoV-2 Infection and Vaccination in Children Aged 5-11 years: Expansion of Existing CITF-Supported Pediatric Studies (2021)
8. JDRF Canada: JDRF Centre of Excellence at UBC (2021)
9. CIHR Team Grant: Allogeneic thymus-derived Tregs to prevent chronic inflammation in transplantation (2021)
10. Wellcome Leap: Building immunity from stem cells for translational disease models (2021)
11. CIHR-JDRF Team Grant: Generation of a functionally robust stem cell based therapy for type 1 diabetes (2021)
12. CIHR Team Grant - Human Immunology Initiative: Innate and adaptive immune regulation in human type 1 diabetes (2019)
13. CIHR: Canadian autoimmunity standardization core (CAN-ASC) (2018)
14. JDRF International: Harmonizing biomarkers in clinical trials of ustekinumab (2018)
15. CIHR: Molecular and cellular biology of T regulatory cells (2017)
1. Outstanding Alumni Award, Simon Fraser University (2022)
2. Faculty of Medicine Distinguished Researcher Award, University of British Columbia (2022)
3. Tier 1 Canada Research Chair in Engineered Immune Tolerance, Government of Canada (2021-2027)
4. Distinguished Achievement, Overall Excellence – Senior Faculty, University of British Columbia (2020)
5. Woman of Distinction, Research, Sciences & Technology, YWCA Metro Vancouver (2020)
6. Recipient of Geoffrey L. Hammond Lectureship (2019)
7. Killam Research Prize in Applied Science & Sciences, University of British Columbia (2016)
8. Genome Canada-CIHR Competition in Personalized Health (2012)
9. Canada Research Chairs in Transplantation Tier II, Government of Canada (2003-2013)
Every day, our researchers work towards breakthroughs to transform the lives of kids in BC and around the world. Learn about our latest innovations and advancements in child health.
For the first time, researchers at UBC have demonstrated how to reliably produce an important type of human immune cell, known as helper T cells, from stem cells in a controlled laboratory setting.
Dr. Megan Levings and her team have recently published two papers on the very different functions and uses of regulatory T cells (Tregs). Tregs are immune cells that help to rein in immune responses to ensure that they don’t go too far and begin harming healthy tissues in their pursuit of foreign invaders. Researchers are still…
On Monday, October 6, 2025 The Nobel Assembly at Karolinska Institutet awarded the Nobel Prize in Physiology or Medicine 2025 to Dr. Mary E. Brunkow, Dr. Fred Ramsdell, and Dr. Shimon Sakaguchi for their discoveries concerning peripheral immune tolerance.
At BC Children’s, we are making discoveries that save lives and transform health care for children in our province and around the world. Our research portfolio includes basic, clinical, population, and public health research.
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BC Children's Hospital Research Institute operates on the ancestral and unceded territory of the Coast Salish peoples — xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh (Squamish), and Səl̓ílwətaʔ/Selilwitulh (Tsleil-Waututh) Nations. Further, this acknowledgement, gratitude, and respect extends to all of the First Nations communities on whose territories the Research Institute builds relationships and operates in British Columbia.
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