Michael Anglesio

PhD

Affiliate Investigator, BC Children's Hospital
Associate Member, Department of Pathology and Laboratory Medicine, University of British Columbia
Member, Women's Health Research Institute
Member, Gynecological Cancer Initiative
Co-Founder, Molecular and Advanced Pathology Core, Department of Pathology and Laboratory Medicine, University of British Columbia

Dr. Anglesio's research has focused primarily on defining subtypes of ovarian cancer. In particular, genomic and protein-based biomarker studies that differentiate types and subtypes of each ovarian cancer histology. Most recently he has been focused on uncovering the mechanism through which endometriosis may become malignant and progress into either clear cell or endometrioid ovarian cancer. In 2017 Dr. Anglesio's group was first to provide evidence that roughly 1/3 of endometriosis frequently harbours cancer-driver mutations, and that these mutations are restricted to only one of two cell types that make up endometriosis.

Academic Affiliations

  • Assistant Professor, , Department of Obstetrics and Gynaecology, Faculty of Medicine, University of British Columbia
  • Research Theme: Healthy Starts
  • Research Group(s): Origins of Child Health and Disease; Pathways to Healthy Birth

Contact Information

Location

Room 275, 2660 Oak Street, Vancouver, British Columbia, Canada, V6H 3Z6

Grants

CIHR Early Career Investigator Operating Grant: Endometriosis Microenvironment: Influence of "Cancer-Driver" Mutations

NIH R37 Project Grant (Co-Applicant): High-throughput Epigenomic Mapping of Regulatory Elements in Ovarian Cancer at Basepair Resolution

CIHR Project Grant (Co-Pl): Sexual Pain in Endometriosis: Role of Somatic Mutations and Local Neurogenesis

Honours & Awards

2016/5 - Department of Pathology and Laboratory Medicine Award for Excellence in Mentoring, University of British Columbia

2019/1- Most impactful paper published in 2017 from the Columbia Hospital for Women Research Foundation (CHWRF) with reference to: Anglesio et al. N Eng J Med 2017. Cancer-Associated Mutations in Endometriosis without Cancer

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