William T. Gibson

FRCPS, BSc, FCCMG, PhD, MD

Investigator, BC Children's Hospital
Senior Clinician Scientist, Laboratory for Obesity Genetics and Indirect Calorimetry (LOGIC), BC Children's Hospital Research Institute

We recruit patients and families with rare genetic diseases, and try to solve the underlying genetic cause by finding different mutations in the same gene among unrelated families with similar diseases.

We have been successful in finding mutations in major “epigenes” – these are genes that code for proteins that open DNA up to activate it, or close it down to keep it quiet. We hope that the rare syndromes we have described will help us learn how these epigenetic programs can increase or decrease the risks for common diseases in the general population.