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David W Scheifele
FRCPC, MD

Investigator Emeritus, BC Children's Hospital

I am one of the original founders of the Vaccine Evaluation Center, a leading centre for applied vaccine research in Canada. Six researchers contribute to the VEC’s core research program, including S. Dobson, T. Kollmann, L. Sauvé, J. Bettinger, S.Gantt, and several more collaborate from other local institutions (BCCDC, VCHA). The researchers share a field team (coordinators, nurses, assistants), data management group (manager, statistician, assistants) and specialized laboratory. The main research themes involve disease burden studies, vaccine clinical trials, and studies to fine tune public immunization programs, including ongoing assessment of vaccine safety. The Vaccine Center researchers collaborate with vaccine specialists across the country and with provincial and federal health officials, with the goal of efficiently translating new vaccine products into optimal vaccination programs for children and adults.

Academic Affiliations

  • Professor Emeritus/a, Division of Infectious and Immunological Diseases, Department of Pediatrics, Faculty of Medicine, University of British Columbia
  • Research Theme: Healthy Starts

Contact Information

Location

4500 Oak St, Vancouver, BC, Canada, V6H 3N1

(604) 875-2472

dscheifele@bcchr.ubc.ca

Streptococcus pneumoniae-associated hemolytic uremic syndrome Canadian Immunization Monitoring Program ACTive National Pediatric Surveillance (1991 to 2019)

Paediatrics & Child Health

Lauren Dagyung Lee and Nirma Khatri Vadlamudi and Katherine Yu and Manish Sadarangani and Nicole Le Saux and Joanne Embree and James D Kellner and Shaun K Morris and Scott A Halperin and Julie A Bettinger and for Members of the Canadian Immunization Monitoring Program, Active (IMPACT) and N Bridger and Cheryl Foo and S A Halperin and K A Top and R Thibeault and J Papenburg and M Lebel and N Le Saux and S Morris and J Embree and B Tan and Athena McConnell and T Jadavji and C Constantinescu and W Vaudry and D Scheifele and M Sadarangani and J Bettinger and L Sauv

DOI: 10.1093/pch/pxae055

09 / 2024

Clinical Presentations and Outcomes of Children in Canada with Recurrent Invasive Pneumococcal Disease from the IMPACT Surveillance Network

Pediatric Infectious Disease Journal

Murad, Y. and Hung, T.-Y. and Sadarangani, M. and Morris, S.K. and Le Saux, N. and Vanderkooi, O.G. and Kellner, J.D. and Tyrrell, G.J. and Martin, I. and Demczuk, W. and Halperin, S.A. and Bettinger, J.A. and Bridger, N. and Foo, C. and Halperin, S.A. and Top, K.A. and Thibeault, R. and Moore, D. and Papenburg, J. and Lebel, M. and Le Saux, N. and Morris, S. and Embree, J. and Tan, B. and McConnell, A. and Jadavji, T. and Constantinescu, C. and Vaudry, W. and Scheifele, D. and Sadarangani, M. and Bettinger, J. and Sauv, L.

DOI: 10.1097/INF.0000000000003454

Immunogenicity of 2 and 3 Doses of the Quadrivalent Human Papillomavirus Vaccine up to 120 Months Postvaccination: Follow-up of a Randomized Clinical Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Donken R and Dobson SRM and Marty KD and Cook D and Sauvageau C and Gilca V and Dionne M and McNeil S and Krajden M and Money D and Kellner J and Scheifele DW and Kollmann T and Ogilvie GS

DOI: 10.1093/cid/ciz887 PubMed: 31617568

08 / 2020

Randomized Trial of 2 Schedules of Meningococcal B Vaccine in Adolescents and Young Adults, Canada1.

Emerging infectious diseases

Langley JM and Gantt S and Quach C and Bettinger JA and Halperin SA and Mutch J and McNeil SA and Ward BJ and MacKinnon-Cameron D and Ye L and Marty K and Scheifele D and Brown E and Canadian Immunization Research Network

DOI: 10.3201/eid2603.190160 PubMed: 32091358

03 / 2020

Will Infant Hepatitis B Immunization Protect Adults?

The Pediatric infectious disease journal

Scheifele DW

DOI: 10.1097/inf.0000000000002326 PubMed: 31205248

06 / 2019

Burden of Children Hospitalized With Pertussis in Canada in the Acellular Pertussis Vaccine Era, 1999-2015.

Journal of the Pediatric Infectious Diseases Society

Abu-Raya B and Bettinger JA and Vanderkooi OG and Vaudry W and Halperin SA and Sadarangani M and Members of the Canadian Immunization Monitoring Program and Active (IMPACT)

DOI: 10.1093/jpids/piy128 PubMed: 30535079

12 / 2018

Fever prophylaxis can reduce vaccine responses: A caution

Paediatrics & Child Health

David Scheifele and Brian Ward

DOI: 10.1093/pch/pxy011

03 / 2018

Cellular immune responses of older adults to four influenza vaccines: Results of a randomized, controlled comparison.

Human vaccines & immunotherapeutics

DOI: 10.1080/21645515.2017.1337615 PubMed: 28635557

09 / 2017

Adverse events following live-attenuated intranasal influenza vaccination of children with cystic fibrosis: Results from two influenza seasons.

Vaccine

DOI: 10.1016/j.vaccine.2017.07.068 PubMed: 28774563

09 / 2017

Maternal immunisation: collaborating with mother nature.

The Lancet. Infectious diseases

DOI: 10.1016/s1473-3099(17)30229-3 PubMed: 28433705

07 / 2017

Will Infant Hepatitis B Vaccination Protect Into Adulthood?: Extended Canadian Experience After a 2-, 4- and 6-month Immunization Schedule.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0000000000001543 PubMed: 28134742

06 / 2017

Viral interference and the live-attenuated intranasal influenza vaccine: Results from a pediatric cohort with cystic fibrosis.

Human vaccines & immunotherapeutics

DOI: 10.1080/21645515.2017.1287641 PubMed: 28273006

06 / 2017

Pertussis and influenza immunisation during pregnancy: a landscape review.

The Lancet. Infectious diseases

DOI: 10.1016/s1473-3099(17)30190-1 PubMed: 28433704

04 / 2017

Do Dose Numbers Matter?: Evaluation of Differing Infant and Toddler Meningococcal C Conjugate Vaccine Programs in Canadian Children.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0000000000001278 PubMed: 27753770

11 / 2016

Influenza Virus Detection Following Administration of Live-Attenuated Intranasal Influenza Vaccine in Children With Cystic Fibrosis and Their Healthy Siblings.

Open forum infectious diseases

DOI: 10.1093/ofid/ofw187 PubMed: 27747255

10 / 2016

Hospitalization for Influenza A Versus B.

Pediatrics

DOI: 10.1542/peds.2015-4643 PubMed: 27535144

09 / 2016

Immunogenicity and safety of 3-dose primary vaccination with combined DTPa-HBV-IPV/Hib vaccine in Canadian Aboriginal and non-Aboriginal infants.

Vaccine

DOI: 10.1016/j.vaccine.2015.02.015 PubMed: 25701314

04 / 2015

Outcomes of invasive meningococcal disease in adults and children in Canada between 2002 and 2011: a prospective cohort study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DOI: 10.1093/cid/civ028 PubMed: 25605282

04 / 2015

Canadian vaccine research networks: Vaccine safety resources for Canada.

Canada communicable disease report = Releve des maladies transmissibles au Canada

McCarthy J and Halperin SA and Bettinger JA and Langley JM and Crowcroft NS and Deeks S and Kwong JC and De Serres G and Top K and McNeil S and Scheifele DW and Canadian Immunization Research Network (CIRN) Investigators

PubMed: 29769957

02 / 2015

AMMI Canada 2015 Annual Conference: Abstracts: April 16 " 18, 2015 Charlottetown, Prince Edward Island.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

The Canadian Immunization Monitoring Program, ACTive (IMPACT): Active surveillance for vaccine adverse events and vaccine-preventable diseases.

Canada communicable disease report = Releve des maladies transmissibles au Canada

Bettinger JA and Halperin SA and Vaudry W and Law BJ and Scheifele DW and Canadian IMPACT members

PubMed: 29769912

12 / 2014

A randomized study to evaluate the immunogenicity and safety of a heptavalent diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, haemophilus influenzae b, and meningococcal serogroup C combination vaccine administered to infants at 2, 4 and 12 months of age.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0000000000000468 PubMed: 25037033

12 / 2014

1087Immunogenicity and Safety of 3-Dose Primary Vaccination with Combined DTPa-HBV-IPV/Hib Vaccine in Canadian Aboriginal and non-Aboriginal Infants.

Open forum infectious diseases

Scheifele DW and Ferguson M and Predy G and Dawar M and Assudani D and Kuriyakose S and Van Der Meeren O and Han HH

DOI: 10.1093/ofid/ofu052.795

12 / 2014

The impact of the meningococcal serogroup C conjugate vaccine in Canada between 2002 and 2012.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DOI: 10.1093/cid/ciu597 PubMed: 25069868

11 / 2014

Discussing the need for an adolescent hepatitis B vaccine booster in infant vaccinees

Paediatrics & Child Health

Michelle Pinto and David Scheifele

DOI: 10.1093/pch/19.8.404

10 / 2014

Burden of seasonal influenza in children with neurodevelopmental conditions.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0000000000000272 PubMed: 24918745

07 / 2014

Trends in asymptomatic nasopharyngeal colonization with streptococcus pneumoniae after introduction of the 13-valent pneumococcal conjugate vaccine in Calgary, Canada.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0000000000000267 PubMed: 24463806

07 / 2014

Childhood immunization rates in Canada are too low: UNICEF

Paediatrics & Child Health

David W Scheifele and Scott A Halperin and Julie A Bettinger

DOI: 10.1093/pch/19.5.237

05 / 2014

High Level Antibody Avidity is Achieved in HIV-Seropositive Recipients of an Inactivated Split Adjuvanted (AS03A) Influenza Vaccine

Journal of Clinical Immunology

Karen K. Yam and Erica Gipson and Marina Klein and Sharon Walmsley and David Haase and Scott Halperin and David Scheifele and Brian J. Ward and Curtis Cooper

DOI: 10.1007/s10875-014-0054-z

05 / 2014

Immunization delivery in British Columbia: perspectives of primary care physicians.

Canadian family physician Medecin de famille canadien

PubMed: 24627403

03 / 2014

Approved but non-funded vaccines: Accessing individual protection

Vaccine

David W. Scheifele and Brian J. Ward and Scott A. Halperin and Shelly A. McNeil and Natasha S. Crowcroft and Gordean Bjornson

DOI: 10.1016/j.vaccine.2013.12.027

02 / 2014

Knowledge, attitudes, beliefs and behaviours of older adults about pneumococcal immunization, a Public Health Agency of Canada/Canadian Institutes of Health Research Influenza Research Network (PCIRN) investigation.

BMC public health

DOI: 10.1186/1471-2458-14-442 PubMed: 24884433

Immunization delivery in British Columbia:Perspectives of primary care physicians

Canadian Family Physician

Omura, J. and Buxton, J. and Kaczorowski, J. and Catterson, J. and Andrea Derban, J.L. and Hasselback, P. and Machin, S. and Linekin, M. and Morgana, T. and O'Briain, B. and Scheifele, D. and Dawar, M.

Diversity of Canadian meningococcal serogroup B isolates and estimated coverage by an investigational meningococcal serogroup B vaccine (4CMenB).

Vaccine

DOI: 10.1016/j.vaccine.2013.03.063 PubMed: 23588089

12 / 2013

Applicability of the Brighton Collaboration Case Definition for seizure after immunization in active and passive surveillance in Canada.

Vaccine

DOI: 10.1016/j.vaccine.2013.09.048 PubMed: 24099871

11 / 2013

Safety, immunogenicity, and tolerability of three influenza vaccines in older adults: results of a randomized, controlled comparison.

Human vaccines & immunotherapeutics

DOI: 10.4161/hv.25580 PubMed: 23839537

11 / 2013

Elevated inflammatory mediators in adults with oculorespiratory syndrome following influenza immunization: a public health agency of Canada/Canadian Institutes of Health Research Influenza Research Network Study.

Clinical and vaccine immunology : CVI

DOI: 10.1128/cvi.00659-12 PubMed: 23697573

08 / 2013

Response to the changing epidemiology of meningococcal disease in North America 1945-2010.

Human vaccines & immunotherapeutics

DOI: 10.4161/hv.24009 PubMed: 23454840

06 / 2013

Immunogenicity of 2 doses of HPV vaccine in younger adolescents vs 3 doses in young women: a randomized clinical trial.

JAMA

DOI: 10.1001/jama.2013.1625 PubMed: 23632723

05 / 2013

Controlling serogroupB invasive meningococcal disease: the Canadian perspective.

Expert review of vaccines

DOI: 10.1586/erv.13.30 PubMed: 23659299

05 / 2013

Unusual patterns of IgG avidity in some young children following two doses of the adjuvanted pandemic H1N1 (2009) influenza virus vaccine.

Clinical and vaccine immunology : CVI

DOI: 10.1128/cvi.00619-12 PubMed: 23345582

04 / 2013

Safety and immunogenicity of 2010"2011 A/H1N1pdm09-containing trivalent inactivated influenza vaccine in adults previously given AS03-adjuvanted H1N1 2009 pandemic vaccine: results of a randomized trial.

Human vaccines & immunotherapeutics

DOI: 10.4161/hv.22619 PubMed: 23570051

01 / 2013

The disease burden of invasive meningococcal serogroup B disease in Canada.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e3182706b89 PubMed: 22926207

01 / 2013

How best to describe the risk of meningococcal B infection?

Paediatrics & Child Health

Manish Sadarangani and Julie A Bettinger and David W Scheifele

DOI: 10.1093/pch/18.10.543

Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v).

The Journal of infectious diseases

DOI: 10.1093/infdis/jis500 PubMed: 22872731

12 / 2012

The effect of funded varicella immunization programs on varicella-related hospitalizations in IMPACT centers, Canada, 2000-2008.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e318260cc4d PubMed: 22647896

09 / 2012

Comparison of children hospitalized with seasonal versus pandemic influenza A, 2004-2009.

Pediatrics

DOI: 10.1542/peds.2011-3216 PubMed: 22931901

09 / 2012

Compatibility of ASO3-adjuvanted H1N1pdm09 and seasonal trivalent influenza vaccines in adults: results of a randomized, controlled trial.

Vaccine

DOI: 10.1016/j.vaccine.2012.05.029 PubMed: 22652402

07 / 2012

Evaluation of meningococcal serogroup C conjugate vaccine programs in Canadian children: interim analysis.

Vaccine

DOI: 10.1016/j.vaccine.2012.04.034 PubMed: 22537988

06 / 2012

Safety and immunogenicity of 2010-2011 H1N12009-containing trivalent inactivated influenza vaccine in children 12-59 months of age previously given AS03-adjuvanted H1N12009 pandemic vaccine: a PHAC/CIHR Influenza Research Network (PCIRN) study.

Vaccine

DOI: 10.1016/j.vaccine.2012.03.046 PubMed: 22469860

05 / 2012

Immunogenicity of a half-dose of adjuvanted 2009 pandemic H1N1 influenza vaccine in adults: a prospective cohort study.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

DOI: 10.1007/s10096-011-1352-5 PubMed: 21796343

04 / 2012

Safety and immunogenicity of a 13-valent pneumococcal conjugate vaccine in healthy infants and toddlers given with routine pediatric vaccinations in Canada.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e318233049d PubMed: 21960186

01 / 2012

Immune responses in adults to revaccination with a tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine 10 years after a previous dose.

Vaccine

DOI: 10.1016/j.vaccine.2011.11.035 PubMed: 22115634

01 / 2012

High-Level Immunogenicity Is Achieved Vaccine With Adjuvanted Pandemic H1N12009 and Improved With Booster Dosing in a Randomized Trial of HIV-Infected Adults

HIV Clinical Trials

DOI: 10.1310/hct1301-23

01 / 2012

High-Level Immunogenicity Is Achieved Vaccine With Adjuvanted Pandemic H1N12009 and Improved With Booster Dosing in a Randomized Trial of HIV-Infected Adults

HIV Clinical Trials

Curtis Cooper and Marina Klein and Sharon Walmsley and David Haase and Donna MacKinnon-Cameron and Kimberley Marty and Yan Li and Bruce Smith and Scott Halperin and Barb Law and David Scheifele

DOI: 10.1310/hct1301-023

01 / 2012

Cost effectiveness of infant vaccination for rotavirus in Canada.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

DOI: 10.1155/2012/327054 PubMed: 23730312

Strategies for successful rapid trials of influenza vaccine.

Clinical trials (London, England)

DOI: 10.1177/1740774511419868 PubMed: 21900340

12 / 2011

Can children with minor illnesses be safely immunized?

Paediatrics & Child Health

Keswadee Lapphra and David Scheifele

DOI: 10.1093/pch/16.8.463

10 / 2011

The responses of Aboriginal Canadians to adjuvanted pandemic (H1N1) 2009 influenza vaccine.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

DOI: 10.1503/cmaj.110196 PubMed: 21788422

09 / 2011

Randomized controlled trial of dose response to influenza vaccine in children aged 6 to 23 months.

Pediatrics

DOI: 10.1542/peds.2010-2777 PubMed: 21768314

08 / 2011

Evaluation of adjuvanted pandemic H1N1(2009) influenza vaccine after one and two doses in young children.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e3182068f33 PubMed: 21178654

05 / 2011

Severe genital ulceration in an acute epstein-barr virus infection.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e3181f41b2e PubMed: 20736877

02 / 2011

Adverse neurologic reactions after both doses of pandemic H1N1 influenza vaccine with optic neuritis and demyelination.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e3181f11126 PubMed: 20686434

01 / 2011

Heterogeneity of rotavirus testing and admitting practices for gastroenteritis among 12 tertiary care pediatric hospitals: Implications for surveillance.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

DOI: 10.1155/2011/656404 PubMed: 22379483

Optimizing Canadian public immunization programs: a prescription for action.

Canadian journal of public health = Revue canadienne de sante publique

PubMed: 21714317

Optimizing Canadian public immunization programs: A prescription for action

Canadian Journal of Public Health

Scheifele, D.W. and Naus, M. and Crowcroft, N.S. and Dobson, S. and Halperin, S.A. and Bjornson, G.

DOI: 10.1007/bf03404894

Hospital acquired rotavirus infections: Burden in canadian paediatric hospitals

Journal of Sports Economics

Le Saux, N. and Bettinger, J. and Halperin, S. and Vaudry, W. and Scheifele, D.

DOI: 10.1177/1757177411402409

Cortisol, behavior, and heart rate reactivity to immunization pain at 4 months corrected age in infants born very preterm.

The Clinical journal of pain

DOI: 10.1097/ajp.0b013e3181e5bb00 PubMed: 20664338

10 / 2010

Substantial morbidity for hospitalized children with community-acquired rotavirus infections: 2005-2007 IMPACT surveillance in Canadian hospitals.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e3181e20c94 PubMed: 20467353

09 / 2010

A nationwide survey of past hepatitis A infections among Canadian adults

Vaccine

David W. Scheifele and Gaston De Serres and Vladimir Gilca and Bernard Duval and Ruth Milner and Margaret Ho and Jan J. Ochnio

DOI: 10.1016/j.vaccine.2010.05.076

07 / 2010

Regrettable lack of definition of the well tolerated vaccine

Vaccine

David Scheifele and Scott Halperin and Danuta Skowronski and James Kellner and Brian Ward and Ian Gemmill and Gaston De Serres

DOI: 10.1016/j.vaccine.2010.03.037

05 / 2010

Pandemic influenza in Canadian children: a summary of hospitalized pediatric cases.

Vaccine

DOI: 10.1016/j.vaccine.2010.02.044 PubMed: 20189488

04 / 2010

Postvaccination Thrombocytopenia in Canada

The Pediatric Infectious Disease Journal

Laura J. Sauv and Julie Bettinger and David Scheifele and Scott Halperin and Wendy Vaudry and Barbara Law

DOI: 10.1097/inf.0b013e3181d2bb45

02 / 2010

The effect of routine vaccination on invasive pneumococcal infections in Canadian children, Immunization Monitoring Program, Active 2000"2007

Vaccine

Julie A. Bettinger and David W. Scheifele and James D. Kellner and Scott A. Halperin and Wendy Vaudry and Barbara Law and Gregory Tyrrell

DOI: 10.1016/j.vaccine.2009.12.026

02 / 2010

Cellular immunity as a potential cause of local reactions to booster vaccination with diphtheria and tetanus toxoids and acellular pertussis antigens.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e3181a9cc2a PubMed: 19755930

11 / 2009

Does vaccination with the varicella vaccine within four weeks after the measles, mumps and rubella vaccine reduce protection?

Paediatrics & Child Health

Keswadee Lapphra and David Scheifele

DOI: 10.1093/pch/14.8.501

10 / 2009

Pediatric combined formulation DTaP"IPV/Hib vaccine

Expert Review of Vaccines

Craig White and Scott A Halperin and David W Scheifele

DOI: 10.1586/erv.09.59

07 / 2009

Changing epidemiology of invasive pneumococcal disease in Canada, 1998-2007: update from the Calgary-area Streptococcus pneumoniae research (CASPER) study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DOI: 10.1086/599827 PubMed: 19508165

07 / 2009

Epidemiology of pertussis and Haemophilus influenzae type b disease in Canada with exclusive use of a diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b pediatric combination vaccine and an adolescent-adult tetanus-diphtheria-acellular pertussis vaccine: implications for disease prevention in the United States.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e318199d2fc PubMed: 19436236

06 / 2009

Safety and immunogenicity of a measles-mumps-rubella-varicella vaccine given as a second dose in children up to six years of age.

Vaccine

DOI: 10.1016/j.vaccine.2009.02.044 PubMed: 19428882

05 / 2009

Vaccination site reaction or bacterial cellulitis?

Paediatrics & Child Health

Keswadee Lapphra and David Scheifele

DOI: 10.1093/pch/14.4.245

04 / 2009

The impact of childhood meningococcal serogroup C conjugate vaccine programs in Canada.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e31819040e7 PubMed: 19209096

03 / 2009

Do childhood vaccines cause thrombocytopenia?

Paediatrics & Child Health

Laura J Sauv and David Scheifele

DOI: 10.1093/pch/14.1.31

01 / 2009

Profile of serogroup Y meningococcal infections in Canada: Implications for vaccine selection.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

PubMed: 21119789

IMPACT after 17 years: Lessons learned about successful networking

Canadian Journal of Infectious Diseases and Medical Microbiology

Scheifele, D.

DOI: 10.1155/2009/348930

Profile of serogroup Y meningococcal infections in Canada: Implications for vaccine selection

Canadian Journal of Infectious Diseases and Medical Microbiology

Le Saux, N. and Bettinger, J.A. and Wootton, S. and Halperin, S.A. and Vaudry, W. and Scheifele, D.W. and Tsang, R.

DOI: 10.1155/2009/871071

Children hospitalized with influenza during the 2006-2007 season: a report from the Canadian Immunization Monitoring Program, Active (IMPACT).

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 19368059

12 / 2008

Ongoing control of Haemophilus influenzae type B infections in Canadian children, 2004-2007.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e31816fc339 PubMed: 18594482

08 / 2008

Influenza vaccination in paediatric nurses: Cross-sectional study of coverage, refusal, and factors in acceptance

Vaccine

Seamus P. Norton and David W. Scheifele and Julie A. Bettinger and Robert M. West

DOI: 10.1016/j.vaccine.2008.03.033

06 / 2008

Effects of Routine Infant Vaccination With the 7-Valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization With Streptococcus pneumoniae in Children in Calgary, Canada

The Pediatric Infectious Disease Journal

James D. Kellner and David Scheifele and Otto G. Vanderkooi and Judy MacDonald and Deirdre L. Church and Gregory J. Tyrrell

DOI: 10.1097/inf.0b013e3181658c5c

06 / 2008

The epidemiology of children hospitalized with herpes zoster in Canada: Immunization Monitoring Program, Active (IMPACT), 1991-2005.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e31815948b5 PubMed: 18174867

02 / 2008

How long can we expect pertussis protection to last after the adolescent booster dose of tetanus-diphtheria-pertussis (Tdap) vaccines?

Paediatrics & child health

PubMed: 19043506

12 / 2007

Invasive infections caused by haemophilus influenzae serotypes in twelve Canadian IMPACT centers, 1996-2001.

The Pediatric infectious disease journal

DOI: 10.1097/inf.0b013e31812f4f5b PubMed: 17984810

11 / 2007

Erythema Nodosum, Mycobacterium avium Lymphadenitis, and a 15-mm Mantoux Test

The Pediatric Infectious Disease Journal

Heidi Budden and Rolando Ulloa-Gutierrez and Simon Dobson and David Scheifele

DOI: 10.1097/inf.0b013e31807a2fe1

08 / 2007

Effectiveness of Pneumococcal Conjugate Vaccine in Greater Vancouver, Canada: 2004-2005

The Pediatric Infectious Disease Journal

DOI: 10.1097/inf.0b013e31803c56df

06 / 2007

The challenges facing Canadian trialists in an increasingly competitive global market: What can be done to remain competitive?

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

DOI: 10.1155/2007/635372 PubMed: 18923723

05 / 2007

Immunologic Considerations for the Timing of the Booster Dose of 7-Valent Pneumococcal Conjugate Vaccine in Young Children

The Pediatric Infectious Disease Journal

David W. Scheifele and Scott A. Halperin and Jan J. Ochnio and Michelle Mozel and Denzyl Duarte-Monteiro and David Wortzman

DOI: 10.1097/01.inf.0000259955.66171.0c

05 / 2007

Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection

Clinical Immunology

Aaron F. Hirschfeld and Julie A. Bettinger and Rachel E. Victor and Donald J. Davidson and Andrew J. Currie and J. Mark Ansermino and David W. Scheifele and Jordan S. Orange and Stuart E. Turvey

DOI: 10.1016/j.clim.2006.10.012

03 / 2007

The Effect of Changing From Whole-Cell to Acellular Pertussis Vaccine on the Epidemiology of Hospitalized Children With Pertussis in Canada

The Pediatric Infectious Disease Journal

Julie A. Bettinger and Scott A. Halperin and Gaston De Serres and David W. Scheifele and Theresa Tam

DOI: 10.1097/01.inf.0000247055.81541.04

01 / 2007

Invasive pneumococcal infections in Canadian children, 1998-2003: Implications for new vaccination programs

Canadian Journal of Public Health

Bettinger, J.A. and Scheifele, D.W. and Halperin, S.A. and Kellner, J.D. and Tyrrell, G. and Morris, R. and Dry, P. and Moore, D. and Lebel, M. and Le Saux, N. and Ford-Jones, E. and Embree, J. and Tan, B. and Jadavji, T. and Vaudry, W. and Davis, M.A.

DOI: 10.1007/bf03404320

Participant-collected, mail-delivered oral fluid specimens can replace traditional serosurveys: a demonstration-of-feasibility survey of hepatitis A virus-specific antibodies in adults.

Canadian journal of public health = Revue canadienne de sante publique

PubMed: 17278676

Invasive pneumococcal infections in Canadian children, 1998-2003: implications for new vaccination programs.

Canadian journal of public health = Revue canadienne de sante publique

PubMed: 17441533

Participant-collected, mail-delivered oral fluid specimens can replace traditional serosurveys: A demonstration-of-feasibility survey of hepatitis A virus-specific antibodies in adults

Canadian Journal of Public Health

Ochnio, J.J. and Scheifele, D.W. and Marion, S.A. and Bigham, M. and Patrick, D.M. and Ho, M. and Mozel, M.

DOI: 10.1007/bf03405383

Seven fatal varicella infections in children were potentially avoidable: A report from IMPACT centres from 2000 to 2005.

Paediatrics & child health

PubMed: 19030311

09 / 2006

Surveillance for influenza admissions among children hospitalized in Canadian immunization monitoring program active centers, 2003-2004.

Pediatrics

DOI: 10.1542/peds.2005-2744 PubMed: 16950953

09 / 2006

Assessment of the compatibility of co-administered 7-valent pneumococcal conjugate, DTaP.IPV/PRP-T Hib and hepatitis B vaccines in infants 2-7 months of age.

Vaccine

DOI: 10.1016/j.vaccine.2005.11.021 PubMed: 16356598

03 / 2006

Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus.

The Journal of general virology

DOI: 10.1099/vir.0.81579-0 PubMed: 16476986

03 / 2006

Erratum: A modified vaccine reduces the rate of large injection site reactions to the preschool booster dose of diphtheria-tetanus-acellular pertussis vaccine (Pediatric Infectious Disease Journal (2005) 24 (1059-1066))

Pediatric Infectious Disease Journal

Scheifele, D.W.

DOI: 10.1097/00006454-200603000-00012

Detection of Human Influenza Virus in the Stool of Children

The Pediatric Infectious Disease Journal

Susan H. Wootton and David W. Scheifele and Annie Mak and Martin Petric and Danuta M. Skowronski

DOI: 10.1097/01.inf.0000245097.95543.11

Seven fatal varicella infections in children were potentially avoidable: A report from IMPACT centres from 2000 to 2005

Paediatrics and Child Health

Scheifele, D.W. and Law, B. and Halperin, S.A. and Tam, T.

DOI: 10.1093/pch/11.7.413

Progress in the prevention of pneumococcal infection.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

DOI: 10.1503/cmaj.051150 PubMed: 16275962

11 / 2005

Conforming to ICMJE principles.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

DOI: 10.1503/cmaj.1050172 PubMed: 16301708

11 / 2005

Questions and answers on immunization

Paediatrics & Child Health

David Scheifele and Simon Dobson

DOI: 10.1093/pch/10.7.423

09 / 2005

Seroprevalence of hepatitis A infection in a low endemicity country: a systematic review

BMC Infectious Diseases

Ba' Pham and Bernard Duval and Gaston De Serres and Vladimir Gilca and Andrea C Tricco and Jan Ochnio and David W Scheifele

DOI: 10.1186/1471-2334-5-56

07 / 2005

Serious Adverse Events Associated with Bacille Calmette-Gu??rin Vaccine in Canada

The Pediatric Infectious Disease Journal

Shelley L. Deeks and Michael Clark and David W. Scheifele and Barbara J. Law and Meenakshi Dawar and Nooshin Ahmadipour and Wikke Walop and C Edward Ellis and Arlene King

DOI: 10.1097/01.inf.0000164769.22033.2c

06 / 2005

Nationwide Canadian Study of Hepatitis A Antibody Prevalence Among Children Eight to Thirteen Years Old

The Pediatric Infectious Disease Journal

Bernard Duval and Gaston De Serres and Jan Ochnio and David Scheifele and Vladimir ??ilca

DOI: 10.1097/01.inf.0000164705.74498.86

06 / 2005

Hepatitis A vaccines: the growing case for universal immunisation of children

Expert Opinion on Pharmacotherapy

David W Scheifele

DOI: 10.1517/14656566.6.2.157

02 / 2005

Invasive Haemophilus influenzae type b infections in vaccinated and unvaccinated children in Canada, 2001-2003.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

DOI: 10.1503/cmaj.1031861 PubMed: 15632405

01 / 2005

Oculorespiratory Syndrome After Influenza Immunization in Children

The Pediatric Infectious Disease Journal

Danuta M. Skowronski and Gordean Bjornson and Entesar Husain and Daniel L. Metzger and David W. Scheifele

DOI: 10.1097/01.inf.0000148924.89558.d5

01 / 2005

A Modified Vaccine Reduces the Rate of Large Injection Site Reactions to the Preschool Booster Dose of Diphtheria-Tetanus-Acellular Pertussis Vaccine

The Pediatric Infectious Disease Journal

David W. Scheifele and Scott A. Halperin and Jan J. Ochnio and Alexander C. Ferguson and Danuta M. Skowronski

DOI: 10.1097/01.inf.0000190028.96152.46

Safety and immunogenicity of a pentavalent combination vaccine (diphtheria, tetanus, acellular pertussis, polio, and haemophilus influenzae type B conjugate) when administered as a fourth dose at 15 to 18 months of age.

Human vaccines

DOI: 10.4161/hv.1.5.2079 PubMed: 17012882

The Prevalence of Hepatitis A in Children in British Columbia

Canadian Journal of Infectious Diseases and Medical Microbiology

Jan J Ochnio and David W Scheifele and Murray Fyfe and Mark Bigham and David Bowering and Paul Martiquet and Margaret Ho and Douglas N Talling

DOI: 10.1155/2005/460983

Canadian Association for Immunization Research and Evaluation (CAIRE) guidelines for industry-sponsored clinical trial and epidemiology contract research.

Human vaccines

DOI: 10.4161/hv.1.4.1971 PubMed: 17012864

Practical questions and answers about childhood immunization

Paediatrics & Child Health

Reka Gustafson and David Scheifele

DOI: 10.1093/pch/9.7.476

09 / 2004

Using vaccine responses to plumb the immunologic consequences of tumor necrosis factor blockade with etanercept.

The Journal of rheumatology

PubMed: 15229937

07 / 2004

Lack of Evidence of Encephalopathy Related to Pertussis Vaccine : Active Surveillance by IMPACT, Canada, 1993"2002

The Pediatric Infectious Disease Journal

Dorothy L. Moore and Nicole Le Saux and David Scheifele and Scott A. Halperin

DOI: 10.1097/01.inf.0000130075.56368.02

06 / 2004

Using vaccine responses to plumb the immunologic consequences of tumor necrosis factor blockade with etanercept

Journal of Rheumatology

Scheifele, D.W.

Injection-site reactions to booster doses of acellular pertussis vaccine: rate, severity, and anticipated impact.

Pediatrics

DOI: 10.1542/peds.112.6.e453 PubMed: 14654644

12 / 2003

For coughs, colds and SARS, wear a mask.

Paediatrics & child health

DOI: 10.1093/pch/8.10.601 PubMed: 20019847

12 / 2003

Decrease in hospital admissions for febrile seizures and reports of hypotonic-hyporesponsive episodes presenting to hospital emergency departments since switching to acellular pertussis vaccine in Canada: a report from IMPACT.

Pediatrics

DOI: 10.1542/peds.112.5.e348 PubMed: 14595075

11 / 2003

Predictors of death in infants hospitalized with pertussis: a case-control study of 16 pertussis deaths in Canada

The Journal of Pediatrics

Lynda K Mikelova and Scott A Halperin and David Scheifele and Bruce Smith and Elizabeth Ford-Jones and Wendy Vaudry and Taj Jadavji and Barbara Law and Dorothy Moore

DOI: 10.1067/s0022-3476(03)00365-2

11 / 2003

Randomized, double-blind, placebo-controlled trial to assess the rate of recurrence of oculorespiratory syndrome following influenza vaccination among persons previously affected.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DOI: 10.1086/378274 PubMed: 14523770

10 / 2003

Immunization monitoring program, active: a model of active surveillance of vaccine safety

Seminars in Pediatric Infectious Diseases

David W Scheifele and Scott A Halperin

DOI: 10.1016/s1045-1870(03)00036-0

07 / 2003

Nature, evolution, and appraisal of adverse events and antibody response associated with the fifth consecutive dose of a five-component acellular pertussis-based combination vaccine

Vaccine

Scott A. Halperin and David Scheifele and Elaine Mills and Roland Guasparini and Garry Humphreys and Luis Barreto and Bruce Smith

DOI: 10.1016/s0264-410x(03)00173-7

06 / 2003

Ocular and Respiratory Symptoms Attributable to Inactivated Split Influenza Vaccine: Evidence from a Controlled Trial Involving Adults

Clinical Infectious Diseases

David W. Scheifele and Bernard Duval and Margaret L. Russell and Richard Warrington and Gaston DeSerres and Danuta M. Skowronski and Marc Dionne and James Kellner and Dele Davies and Judy MacDonald

DOI: 10.1086/368189

04 / 2003

Canada needs a national immunization program: an open letter to the Honourable Anne McLellan, federal minister of health.

CMAJ : Canadian Medical Association Journal

PubMed: 12615750

03 / 2003

Invasive pneumococcal infections among Canadian aboriginal children.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 12632794

03 / 2003

Thrombocytopenia after immunization of Canadian children, 1992 to 2001

The Pediatric Infectious Disease Journal

TAJ JADAVJI and DAVID SCHEIFELE and SCOTT HALPERIN

DOI: 10.1097/01.inf.0000048961.08486.d1

02 / 2003

Unique roles of a data and safety monitoring board in vaccine safety trials with compressed timelines and urgent implications

Controlled Clinical Trials

David Scheifele and Bernard Duval and Gaston De Serres and Danuta M Skowronski

DOI: 10.1016/s0197-2456(02)00269-6

02 / 2003

Thrombocytopenia after immunization of Canadian children, 1992 to 2001.

The Pediatric infectious disease journal

DOI: 10.1097/00006454-200302000-00006 PubMed: 12586974

02 / 2003

Immunization practice: Selecting the injection site

Vaccines: Children and Practice

Scheifele, D.W.

Canada needs a national immunization program: An open letter to the Honourable Anne McLellan, federal minister of health

CMAJ

Naus, M. and Scheifele, D.W.

Assuring vaccine safety: A celebration of 10 years of progress with the IMPACT project.

Paediatrics & child health

PubMed: 20046444

11 / 2002

Three-year follow-up of protection rates in children given varicella vaccine.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses

DOI: 10.1155/2002/907087 PubMed: 18159415

11 / 2002

Outcome of penicillin-nonsusceptible Streptococcus pneumoniae meningitis: a nested case-control study

The Pediatric Infectious Disease Journal

JAMES D. KELLNER and DAVID W. SCHEIFELE and SCOTT A. HALPERIN and MARC H. LEBEL and DOROTHY MOORE and NICOLLE LE SAUX and E. LEE FORD-JONES and BARBARA LAW and WENDY VAUDRY

DOI: 10.1097/00006454-200210000-00004

10 / 2002

Population-based epidemiology of invasive pneumococcal infection in children in nine urban centers in Canada, 1994 through 1998

The Pediatric Infectious Disease Journal

GORDEAN L. BJORNSON and DAVID W. SCHEIFELE and SCOTT A. HALPERIN

DOI: 10.1097/00006454-200210000-00012

10 / 2002

Hepatitis A vaccine: is it being used to best advantage?

CMAJ : Canadian Medical Association Journal

PubMed: 12137079

07 / 2002

Pelvic inflammatory disease associated with Enterobius vermicularis.

Archives of Disease in Childhood

DOI: 10.1136/adc.86.6.439 PubMed: 12023182

06 / 2002

Emergence of penicillin-nonsusceptible Streptococcus pneumoniae invasive clones in Canada.

Journal of clinical microbiology

DOI: 10.1128/jcm.40.1.68-74.2002 PubMed: 11773094

01 / 2002

Assuring vaccine safety: A celebration of 10 years of progress with the IMPACT project

Paediatrics and Child Health

Scheifele, D.W. and Halperin, S.A. and Gold, R. and Samson, H. and King, A.

DOI: 10.1093/pch/7.9.645

Meningococcal disease and vaccination in North America.

Journal of paediatrics and child health

DOI: 10.1046/j.1440-1754.2001.00679.x PubMed: 11885732

10 / 2001

Historic low Haemophilus influenzae type B case tally--Canada 2000.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 11582620

09 / 2001

Assessment of injection site reactions to an acellular pertussis-based combination vaccine, including novel use of skin tests with vaccine antigens

Vaccine

David W. Scheifele and Scott A. Halperin and Alexander C. Ferguson

DOI: 10.1016/s0264-410x(01)00230-4

09 / 2001

Practical vaccination guidelines for children with cancer.

Paediatrics & child health

PubMed: 20084264

07 / 2001

Population-based surveillance of invasive group A streptococcal disease in British Columbia: 1996 to 1998.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses

DOI: 10.1155/2001/270873 PubMed: 18159345

07 / 2001

Reduced susceptibility to penicillin among pneumococci causing invasive infection in children - Canada, 1991 to 1998.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses

DOI: 10.1155/2001/984958 PubMed: 18159346

07 / 2001

Random Gleanings from the Literature

Paediatrics & Child Health

David W Scheifele

DOI: 10.1093/pch/6.4.199

04 / 2001

Hib conjugate vaccines: lessons learned.

International journal of clinical practice. Supplement

PubMed: 11715364

02 / 2001

Hib conjugate vaccines: Lessons learned

International Journal of Clinical Practice, Supplement

Scheifele, D.

Practical vaccination guidelines for children with cancer

Paediatrics and Child Health

Sung, L. and Heurter, H. and Zokvic, K.M. and Ford-Jones, E.L. and Weitzman, S.S. and Freeman, R. and Dupuis, L.L. and Scheifele, D.W.

DOI: 10.1093/pch/6.6.379

The burden of pneumococcal infections in children

Paediatrics & Child Health

David Scheifele

DOI: 10.1093/pch/6.suppl_b.5b

Pneumococcal disease: Implications in paediatrics

Paediatrics & Child Health

David Scheifele

DOI: 10.1093/pch/6.suppl_b.4b

The challenge of immunizing adolescents: Lessons from the classroom

Vaccines: Children and Practice

Scheifele, D.W.

The Immunization Monitoring Program Active (IMPACT) prospective five year study of Canadian children hospitalized for chickenpox or an associated complication.

The Pediatric infectious disease journal

DOI: 10.1097/00006454-200011000-00005 PubMed: 11099085

11 / 2000

New vaccines and the rising costs of caring

Paediatrics & Child Health

David W Scheifele

DOI: 10.1093/pch/5.7.371

10 / 2000

Population-based incidence rate of invasive pneumococcal infection in children: Vancouver, 1994-1998.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 11042949

09 / 2000

The Immunization Monitoring Program-active (IMPACT) prospective surveillance of varicella zoster infections among hospitalized Canadian Children: 1991-1996.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 10946445

08 / 2000

Invasive pneumococcal infections in Canadian children, 1991-1998: implications for new vaccination strategies. Canadian Paediatric Society/Laboratory Centre for Disease Control Immunization Monitoring Program, Active (IMPACT).

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DOI: 10.1086/313923 PubMed: 10913397

07 / 2000

Haemophilus influenzae type B disease control using PENTACEL, Canada, 1998-1999.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 10920538

06 / 2000

Population-based surveillance of Hib invasive infections in children in British Columbia Alberta and Ontario - 1995 to 1997.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses

DOI: 10.1155/2000/219612 PubMed: 18159280

05 / 2000

Adult formulation of a five component acellular pertussis vaccine combined with diphtheria and tetanus toxoids and inactivated poliovirus vaccine is safe and immunogenic in adolescents and adults.

The Pediatric infectious disease journal

DOI: 10.1097/00006454-200004000-00003 PubMed: 10783014

04 / 2000

School-based hepatitis B vaccination programme and adolescent multiple sclerosis

The Lancet

A Dessa Sadovnick and David W Scheifele

DOI: 10.1016/s0140-6736(99)02991-8

02 / 2000

Erratum: Invasive pneumococcal infections in Canadian children, 1991-1998: Implications for new vaccination strategies. Clin infect dis 2000; 31:58-64 (Clinical Infections Diseases (July 2000) 31 (58-64))

Clinical Infectious Diseases

Scheifele, D. and Halperin, S. and Pelletier, L.

DOI: 10.1086/314018

Evaluation of ready-to-use and multi-dose influenza vaccine formats in large clinic settings.

Canadian journal of public health = Revue canadienne de sante publique

PubMed: 11089283

Vaccinations for immunocompromised children

Vaccines: Children and Practice

Scheifele, D.W.

Tools of the immunization trade: Vials, needles and syringes

Vaccines: Children and Practice

Scheifele, D.W.

Reactogenicity to a Live Attenuated Varicella Vaccine in Canadian Children

Canadian Journal of Infectious Diseases

Francisco Diaz-Mitoma and Scott A Halperin and David Scheifele

DOI: 10.1155/2000/647245

Frequently asked questions

Vaccines: Children and Practice

Scheifele, D.W.

Evaluation of ready-to-use and multi-dose influenza vaccine formats in large clinic settings

Canadian Journal of Public Health

Scheifele, D.W. and Skowronski, D. and King, A. and LaJeunesse, C.A. and Bjornson, G.L. and Parkyn, H. and Walker, N. and Stefura, E.

DOI: 10.1007/bf03404801

Comparison of a fifth dose of a five-component acellular or a whole cell pertussis vaccine in children four to six years of age

The Pediatric Infectious Disease Journal

SCOTT A. HALPERIN and DAVID SCHEIFELE and LUIS BARRETO and CAROLYN PIM and ROLAND GUASPARINI and LORNA MEDD and WILLIAM MEEKISON and BRIAN J. EASTWOOD

DOI: 10.1097/00006454-199909000-00006

09 / 1999

Effect of reminder notices on the timeliness of early childhood immunizations.

Paediatrics & child health

PubMed: 20212950

09 / 1999

Extended follow-up of antibody levels and antigen responsiveness after 2 Haemophilus influenzae type b conjugate vaccines

The Journal of Pediatrics

David W. Scheifele and Scott A. Halperin and Roland Guasparini and William Meekison and Carolyn Pim and Luis Barreto

DOI: 10.1016/s0022-3476(99)70028-4

08 / 1999

Epidemiological features of pertussis in hospitalized patients in Canada, 1991-1997: report of the Immunization Monitoring Program--Active (IMPACT).

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DOI: 10.1086/514792 PubMed: 10451159

06 / 1999

How to increase by 40% the number of pediatric doses recovered from multidose vials of Hepatitis B vaccines

The Pediatric Infectious Disease Journal

DOI: 10.1097/00006454-199906000-00020

06 / 1999

Genotyping of Penicillin-Highly Resistant Invasive Streptococcus pneumoniae Obtained from Canadian Children Early in the Resistance Epidemic

Pediatric Research

David Greenberg and Eshwar Mahenthiralingam and Jim D Kellner and Maureen E Campbell and Debrah A Henry and David P Speert and David W Scheifele

DOI: 10.1203/00006450-199904020-00958

04 / 1999

A comparative study of PENTA vaccine booster doses given at 12, 15 or 18 months of age

Vaccine

David W Scheifele and Roland Guasparini and Pierre Lavigne

DOI: 10.1016/s0264-410x(98)00232-1

02 / 1999

Cow tails and conviction (review of Viruses, plagues, and history).

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

02 / 1999

Initial management of anaphylaxis

Vaccines: Children and Practice

Scheifele, D.W.

False contraindications to immunization of children

Vaccines: Children and Practice

Scheifele, D.W.

Cost of chickenpox in Canada: Part II. Cost of complicated cases and total economic impact

Pediatrics

Law, B. and Fitzsimon, C. and Ford-Jones, L. and McCormick, J. and Rivire, M. and Halperin, S. and Wang, E. and Lebel, M. and Scheifele, D. and MacDonald, N. and Mills, E. and Morris, R. and Dry, P. and Jadavji, T. and Vaudry, W. and Duclos, P. and DeLage, G.

DOI: 10.1542/peds.104.1.7

Universal childhood hepatitis B vaccination: infants vs. preadolescents, the Canadian perspective

The Pediatric Infectious Disease Journal

DAVID SCHEIFELE

DOI: 10.1097/00006454-199807001-00004

07 / 1998

On caring and counting.

Paediatrics & child health

PubMed: 20401248

07 / 1998

Haemophilus influenzae type B disease at 11 pediatric centres, 1996-1997.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 9926485

07 / 1998

On caring and counting

Paediatrics & Child Health

David W Scheifele

DOI: 10.1093/pch/3.4.221

07 / 1998

Disseminated bacille Calmette-Gurin infection: three recent Canadian cases. IMPACT. Immunization Monitoring Program, Active.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 9611413

05 / 1998

A bite in the playroom: Managing human bites in day care settings

Canadian Journal of Infectious Diseases

Delage, G. and Boucher, F. and Embree, J. and Ford-Jones, E. and Speert, D. and Tan, B. and Halsey, N. and King, S. and Scheifele, D. and Tamblyn, S. and Waters, J.

Comparative safety of tetanus-diphtheria toxoids booster immunization in students in Grades 6 and 9

The Pediatric Infectious Disease Journal

DAVID W. SCHEIFELE and SIMON DOBSON and ARLENE KALLOS and GORDEAN BJORNSON and JAN J. OCHNIO

DOI: 10.1097/00006454-199812000-00004

Viral meningitis

Canadian Journal of Infectious Diseases

Delage, G. and Boucher, F. and Embree, J. and Speert, D. and Tan, B. and MacDonald, N. and Marchessault, V. and Halsey, N. and King, S. and Scheifele, D. and Tamblyn, S. and Waters, J.

Respiratory syncytial virus immune globulin intravenous

Canadian Journal of Infectious Diseases

Delage, G. and Boucher, F. and Embree, J. and Ford-Jones, E. and Speert, D. and Tan, B. and MacDonald, N. and Marchessault, V. and Halsey, N. and King, S. and Scheifele, D. and Tamblyn, S. and Waters, J.

Immunization. Point, counterpoint.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 9418668

12 / 1997

Clinical trials and tribulations: a personal view of interacting with pharmaceutical manufacturers.

Clinical and investigative medicine. Medecine clinique et experimentale

PubMed: 9189650

06 / 1997

Hypotonic-hyporesponsive episodes in children hospitalized at 10 Canadian Pediatric Tertiary-Care Centres, 1991-1994.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 9540236

05 / 1997

Pediatric investigators collaborative network on infections in Canada (PICNIC): The politics and positives of a cooperative study group

Journal of Clinical Epidemiology

Elaine E.L. Wang and David Scheifele and Barbara J. Law and Noni E. MacDonald

DOI: 10.1016/s0895-4356(96)00382-4

04 / 1997

New, ultrasensitive enzyme immunoassay for detecting vaccine- and disease-induced hepatitis A virus-specific immunoglobulin G in saliva.

Journal of clinical microbiology

PubMed: 8968887

01 / 1997

Point, counterpoint

CMAJ

Scheifele, D.W.

Hepatitis A Virus Infections in Urban Children"Are Preventive Opportunities Being Missed?

The Journal of Infectious Diseases

JanJ. Ochnio and DavidW. Scheifele and Margaret Ho

DOI: 10.1086/514162

Assessment of parent education methods for infant immunization.

Canadian journal of public health = Revue canadienne de sante publique

PubMed: 9458569

New, Ultrasensitive Enzyme Immunoassay for Detecting Vaccine-and Disease-Induced Hepatitis a Virus-Specific Immunoglobulin G in Saliva

Journal of Clinical Microbiology

Ochnio, J.J. and Scheifele, D.W. and Ho, M. and Mitchell, L.A.

DOI: 10.1128/jcm.35.1.98-101.1997

Assessment of parent education methods for infant immunization

Canadian Journal of Public Health

Bjornson, G.L. and Scheifele, D.W. and Gold, R.

DOI: 10.1007/bf03403916

Clinical trials and tribulations: A personal view of interacting with pharmaceutical manufacturers

Clinical and Investigative Medicine

Scheifele, D.W.

Study of booster doses of two Haemophilus influenzae type b conjugate vaccines including their interchangeability.

Vaccine

DOI: 10.1016/s0264-410x(96)00086-2 PubMed: 8994313

10 / 1996

Penicillin resistance among invasive pneumococcal isolates at 10 children's hospitals, 1991-1994. The LCDC/CPS Impact Group. The Immunization Monitoring Program, Active.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 8917965

10 / 1996

Recent trends in pediatric Haemophilus influenzae type B infections in Canada. Immunization Monitoring Program, Active (IMPACT) of the Canadian Paediatric Society and the Laboratory Centre for Disease Control.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 8625025

04 / 1996

DOES TREATMENT WITH DEXAMETHASONE AFFECT THE IMMUNOLOGICAL RESPONSE TO ANTIGENIC CHALLENGE OF INFANTS BORN PRETERM? 1717

Pediatric Research

Abbas R.M Kingo and David Scheifele and Margaret Pendray and Dan Waisman and Ruth Milner

DOI: 10.1203/00006450-199604001-01741

04 / 1996

Failures after immunization with Haemophilus influenzae type b vaccines--1991-1995.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 8822260

02 / 1996

Travel medicine recommendation: Dengue fever and international travel

CMAJ

Bowie, W. and Gagnon, L.S. and Houston, S. and Kain, K. and MacPherson, D. and Marchessault, V. and Onyett, H. and Saginur, R. and Scheifele, D. and Stratton, F. and Wilson, R. and Carpenter, D. and Gadd, E. and Gushulak, B. and Lobel, H. and McCarthy, A. and Mohanna, S. and Tipple, M. and Paulson, E.

Where is the Varicella Vaccine?

Canadian Journal of Infectious Diseases

David W Scheifele

DOI: 10.1155/1996/151890

Egg allergy and MMR vaccine: New recommendations from the National Advisory Committee on Immunization

Canadian Journal of Infectious Diseases

Scheifele, D. and Spika, J. and Armstrong, N. and Faoki and Dewals, P. and Ford-Jones, E. and Cemmill, I. and Halperin and Law, B. and Naus, M. and Robert, Y. and Ward, B. and Carpenter, L.D. and Carter, A. and Freeman, T. and Hadler, S. and MacPherson, D. and Marchessault, V. and Walters, J. and Duclos, P. and Mustard, C. and Palkonyay, P.

DOI: 10.1155/1996/279825

Assessment of a universal, school-based hepatitis B vaccination program.

JAMA

DOI: 10.1001/jama.1995.03530150033030 PubMed: 7563510

10 / 1995

Effects of freezing on DPT and DPT-IPV vaccines, adsorbed.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 7647743

06 / 1995

Safety and effectiveness of the new inactivated hepatitis A virus vaccine.

CMAJ : Canadian Medical Association Journal

PubMed: 7828098

02 / 1995

Evaluation of booster doses of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine in 18-month-old children

Vaccine

David W. Scheifele and William Meekison and Roland Guasparini and Ann Roberts and Luis Barreto and John Thipphawong and Sharon Wiltsey

DOI: 10.1016/0264-410x(95)80019-a

01 / 1995

Safety and effectiveness of the new inactivated hepatitis A virus vaccine

CMAJ

Furesz, J. and Scheifele, D.W. and Palkonyay, L.

Assessment of a universal, school-based hepatitis B vaccination program

Journal of the American Medical Association

Dobson, S. and Scheifele, D. and Bell, A.

DOI: 10.1001/jama.274.15.1209

Can reductions in diphtheria toxoid or aluminum content reduce the reactogenicity of booster doses of DPT vaccine?

Immunology and Infectious Diseases

Scheifele, D.W. and Meekison, W. and Guasparini, R. and Barreto, L.

Statement on travellers and rabies vaccine

CMAJ

Dumas, S. and Horsman, G. and Keystone, J.S. and Lawee, D. and MacLean, J.D. and MacPherson, D.W. and Robert, J. and Saginur, R. and Scheifele, D. and Wilson, R. and Percheson, P. and Garld, E. and Mohanna, S. and Nowak, R. and Tipple, M. and Jeanes, C.W.L. and Spika, J.S. and Ladouceur, S. and Losos, J. and Herman, S.

Immunization of patients with rheumatoid arthritis against influenza: a study of vaccine safety and immunogenicity.

The Journal of rheumatology

PubMed: 7966058

07 / 1994

Safety and immunogenicity of Haemophilus influenzae vaccine (tetanus toxoid conjugate) administered concurrently or combined with diphtheria and tetanus toxoids, pertussis vaccine and inactivated poliomyelitis vaccine to healthy infants at two, four and six months of age.

The Pediatric infectious disease journal

PubMed: 8072815

05 / 1994

Evaluation of Haemophilus influenzae type b conjugate vaccine (meningococcal protein conjugate) in Canadian infants.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses

DOI: 10.1155/1994/479313 PubMed: 22451769

03 / 1994

Haemophilus B conjugate vaccination failure.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 8193604

03 / 1994

Pertussis in children hospitalized at five Canadian pediatric tertiary care centres.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 8167606

02 / 1994

Role of whole-cell pertussis vaccine in severe local reactions to the preschool (fifth) dose of diphtheria-pertussis-tetanus vaccine.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 8275406

01 / 1994

Local adverse effects of meningococcal vaccine.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 8275404

01 / 1994

Meningococcal disease in children hospitalized at six Canadian pediatric tertiary care centres.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 8161973

01 / 1994

The Changing Face of Childhood Meningitis

Canadian Journal of Infectious Diseases

David Scheifele

DOI: 10.1155/1994/598491

Influenza immunization in children with chronic arthritis [4]

Journal of Rheumatology

Olson, N.Y. and Lindsley, C.B. and Malleson, P. and Scheifele, D.

Role of whole-cell pertussis vaccine in severe local reactions to the preschool (fifth) dose of diphtheria-pertussis-tetanus vaccine

CMAJ

Scheifele, D.W. and Bjornson, G. and Halperin, S.H. and Mitchell, L. and Boraston, S.

Health care budgets and vaccine programs: A time for review and prioritization

CMAJ

Clogg, D. and MacDonald, N.E. and Delage, G. and Halperin, S. and Jadavji, T. and King, S. and Law, B. and Lebel, M. and Gold, R. and Marchessault, V. and Carlson, J. and Dery, P. and Granoff, D. and Scheifele, D.W. and Waters, J.

Dissenting Views on Dexamethasone Therapy for Bacterial Meningitis

Canadian Journal of Infectious Diseases

David W Scheifele

DOI: 10.1155/1994/565214

Safety and immunogenicity of Haemophilus influenzae vaccine (tetanus toxoid conjugate) administered concurrently or combined with diphtheria and tetanus toxoids, pertussis vaccine and inactivated poliomyelitis vaccine to healthy infants at two, four and six months of age

Pediatric Infectious Disease Journal

Gold, R. and Scheifele, D. and Barreto, L. and Wiltsey, S. and Bjornson, G. and Meekison, W. and Guasparini, R. and Medd, L.

DOI: 10.1097/00006454-199405000-00004

Immunization of patients with rheumatoid arthritis against influenza: A study of vaccine safety and immunogenicity

Journal of Rheumatology

Chalmers, A. and Scheifele, D. and Patterson, C. and Williams, D. and Weber, J. and Shuckett, R. and Teufel, A.

Is Haemophilus influenzae type b conjugate vaccine (meningococcal protein conjugate) compatible with diphtheria-pertussis-tetanus vaccine in young infants?

The Pediatric infectious disease journal

PubMed: 8265288

11 / 1993

Can Haemophilus influenzae type b-tetanus toxoid conjugate vaccine be combined with diphtheria toxoid-pertussis vaccine-tetanus toxoid?

CMAJ : Canadian Medical Association Journal

PubMed: 8221449

10 / 1993

Influenza immunization in children with chronic arthritis: a prospective study.

The Journal of rheumatology

PubMed: 7848389

10 / 1993

Decline in Haemophilus influenzae type B invasive infections at five Canadian pediatric centres.

Canada communicable disease report = Releve des maladies transmissibles au Canada

PubMed: 8348103

06 / 1993

Immunogenicity of Haemophilus influenzae type b conjugate vaccine in children with congenital asplenia.

The Journal of infectious diseases

DOI: 10.1093/infdis/167.5.1210 PubMed: 8486956

05 / 1993

Evaluation of inactivated hepatitis A vaccine in Canadians 40 years of age or more.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 8431816

02 / 1993

A Perspective on Vaccine Evaluation Research in Canada: Past and Future

Canadian Journal of Infectious Diseases

David W Scheifele and Aubrey J Tingle

DOI: 10.1155/1993/384058

Influenza immunization in children with chronic arthritis: A prospective study

Journal of Rheumatology

Malleson, P.N. and Tekano, J.L. and Scheifele, D.W. and Weber, J.M.

A controlled comparison of Haemophilus influenzae type B diphtheria toxoid conjugate vaccine given concurrently or in combination with DPT-IPV vaccine to 18-month-old children

Immunology and Infectious Diseases

Barreto, L. and Scheifele, D. and Noseworthy, G. and Stratton, F. and Bjornson, G. and Schaart, W.

HIV antibody testing in children

CMAJ

Clogg, D. and MacDonald, N.E. and Delage, G. and Halperin, S. and Jadavji, T. and King, S. and Law, B. and Lebel, M. and Gold, R. and Marchessault, V. and Granoff, D. and Scheifele, D.W. and Dery, P. and Waters, J.R. and Carlson, J.A.K.

Evaluation of inactivated hepatitis A vaccine in Canadians 40 years of age or more

CMAJ

Scheifele, D.W. and Bjornson, G.J.

Breastfeeding and antibody responses to routine vaccination in infants.

Lancet (London, England)

DOI: 10.1016/0140-6736(92)92589-8 PubMed: 1360102

12 / 1992

Acellular versus whole-cell pertussis vaccines.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses

DOI: 10.1155/1992/564683 PubMed: 22529731

03 / 1992

Controlled trial of Haemophilus influenzae type B diphtheria toxoid conjugate combined with diphtheria, tetanus and pertussis vaccines, in 18-month-old children, including comparison of arm versus thigh injection

Vaccine

David Scheifele and Gordean Bjornson and Luis Barreto and William Meekison and Roland Guasparini

DOI: 10.1016/0264-410x(92)90394-y

01 / 1992

Pediatric immunization for the 1990s.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses

DOI: 10.1155/1992/838160 PubMed: 22451753

01 / 1992

Toward the rational management of herpes infection in pregnant women and their newborn infants

CMAJ

Goldberg, N.A. and MacDonald, N.E. and Delage, G. and Halperin, S. and Jadavji, T. and King, S. and Lapointe, N. and Law, B. and Gold, R. and Marchessault, V. and Phillips, C. and Scheifele, D.W. and Dery, P. and Waters, J.R. and Carlson, J.A.K.

Adverse reactions to the preschool (fifth) dose of adsorbed diphtheria-pertussis-tetanus vaccine in Canadian children.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 1893319

09 / 1991

Comparison of adverse reactions to whole-virion and split-virion influenza vaccines in hospital personnel.

CMAJ : Canadian Medical Association Journal

PubMed: 2070311

08 / 1991

Evaluation of poliovirus-related cases occurring in Canada in 1989.

Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada

PubMed: 2060033

04 / 1991

Adverse reactions to the preschool (fifth) dose of adsorbed diphtheria-pertussis-tetanus vaccine in Canadian children

CMAJ

Scheifele, D.W. and Meekison, W. and Grace, M. and Barreto, L. and Carter, A.O. and Mitchell, L. and Farley, J.

Comparison of adverse reactions to whole-virion and split-virion influenza vaccines in hospital personnel

CMAJ

Al-Mazrou, A. and Scheifele, D.W. and Soong, T. and Bjornson, G.

Role of bacterial toxins in neonatal necrotizing enterocolitis

The Journal of Pediatrics

David W. Scheifele

DOI: 10.1016/s0022-3476(05)81129-1

07 / 1990

Amino acid sequence of a deltalike toxin from Staphylococcus epidermidis.

Infection and immunity

PubMed: 2323825

05 / 1990

Neonatal necrotizing enterocolitis associated with delta toxin-producing methicillin-resistant Staphylococcus aureus

The Pediatric Infectious Disease Journal

GARY D. OVERTURF and MICHAEL P. SHERMAN and DAVID W. SCHEIFELE and LOUISE C. WONG

DOI: 10.1097/00006454-199002000-00005

02 / 1990

Neonatal necrotizing enterocolitis associated with delta toxin-producing methicillin-resistant Staphylococcus aureus.

The Pediatric infectious disease journal

PubMed: 2314957

02 / 1990

Evaluation of adverse events after influenza vaccination in hospital personnel.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 2295029

01 / 1990

Statement on recommended use of measles vaccine in Canada

CMAJ

Tamblyn, S.E. and Carter, A.O. and Ahronheim, G. and Carlson, J.A.K. and Conly, J. and Delage, G. and Dery, P. and Furesz, J. and Gold, R. and Halperin, S.A. and Hammond, G. and Scheifele, D.W. and Waters, J.

Amino acid sequence of a deltalike toxin from Staphylococcus epidermidis

Infection and Immunity

McKevitt, A.I. and Bjornson, G.L. and Mauracher, C.A. and Scheifele, D.W.

Statement on vaccination of children with inadequate immunization records

CMAJ

Tamblyn, S.E. and Carter, A.O. and Ahronheim, G. and Carlson, J.A.K. and Conly, J. and Delage, G. and Dery, P. and Furesz, J. and Gold, R. and Halperin, S.A. and Hammond, G. and Scheifele, D.W. and Waters, J.

Evaluation of adverse events after influenza vaccination in hospital personnel

CMAJ

Scheifele, D.W. and Bjornson, G. and Johnston, J.

Antigenuria after receipt of Haemophilus b diphtheria toxoid conjugate vaccine.

The Pediatric infectious disease journal

PubMed: 2626290

12 / 1989

Evaluation of Canadian poliovirus-related cases.

Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada

PubMed: 2791077

09 / 1989

Post-marketing surveillance of adverse events following ProHIBit vaccine--British Columbia.

Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada

PubMed: 2791073

07 / 1989

Bravo!: Vaccines.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

04 / 1989

Local adverse reactions to adsorbed DPT vaccine--Surrey, British Columbia.

Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada

PubMed: 2706693

04 / 1989

Herpes simplex type 2 aseptic meningitis in a two-month-old infant.

The Pediatric infectious disease journal

PubMed: 2540478

03 / 1989

ANTIGENURIA AFTER RECEIPT OF HAEMOPHILUS b DIPHTHERIA TOXOID CONJUGATE VACCINE

The Pediatric Infectious Disease Journal

David Scheifele and Gordean L. G. Bjornsen and Teri Arcand and Karen Jacobsen

DOI: 10.1097/00006454-198912000-00014

Local adverse reactions to diphtheria and tetanus toxoids and pertussis vaccine, adsorbed, in Surrey, BC

CMAJ

Scheifele, D.W.

Herpes simplex type 2 aseptic meningitis in a two-month-old infant

Pediatric Infectious Disease Journal

Thomas, E.E. and Scheifele, D.W. and Mac Lean, B.S. and Ashley, R.L.

Pertussis vaccine and encephalopathy after the Loveday trial.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

PubMed: 3263895

12 / 1988

Gentamicin penetration into cerebrospinal fluid in experimental Haemophilus influenzae meningitis.

Antimicrobial agents and chemotherapy

DOI: 10.1128/aac.32.7.1034 PubMed: 3190192

07 / 1988

Vaccines for prevention of head and neck infections.

Infectious disease clinics of North America

PubMed: 3074113

03 / 1988

Delta toxin activity in coagulase-negative staphylococci from the bowels of neonates.

Journal of clinical microbiology

PubMed: 3343323

02 / 1988

The contribution of coagulase-negative staphylococci to neonatal necrotizing enterocolitis

Infectious Diseases Newsletter

David W. Scheifele

DOI: 10.1016/0278-2316(88)90010-2

01 / 1988

Delta toxin activity in coagulase-negative Staphylococci from the bowels of neonates

Journal of Clinical Microbiology

Scheifele, D.W. and Bjornson, G.L.

DOI: 10.1128/jcm.26.2.279-282.1988

Management of children infected with human immunodeficiency virus

CMAJ

Gold, R. and Hawkins, A.E. and Halperin, S.A. and Lapointe, N. and Law, B.J. and MacDonald, N. and Mills, E.L. and Carlson, J.A.K. and Dery, P. and Marchessault, V.J.H. and Scheifele, D.W. and Waters, J.R. and Plotkin, S.A.

Erythema infectiosium and parvovirus B19 infection in pregnancy

CMAJ

Hawkins, A.E. and Gold, R. and MacDonald, N.E. and Halperin, S.A. and Lapointe, N. and Law, B.J. and Mills, E.L. and Carlson, J.A. and Dery, P. and Marchessault, V. and Scheifele, D.W. and Waters, J.R. and Plotkin, S.

Pertussis vaccine and encephalopathy after the Loveday trial

CMAJ

Scheifele, D.W.

Delta-like toxin produced by coagulase-negative staphylococci is associated with neonatal necrotizing enterocolitis.

Infection and immunity

PubMed: 3623702

09 / 1987

Early onset Campylobacter sepsis in a neonate.

The Pediatric infectious disease journal

PubMed: 3601501

05 / 1987

Staphylococcus epidermidis-associated enterocolitis

The Journal of Pediatrics

David Scheifele and Gordean Bjornson

DOI: 10.1016/s0022-3476(87)80185-3

02 / 1987

Comparison of two antibiotic regimens for neonatal necrotizing enterocolitis

Journal of Antimicrobial Chemotherapy

David W. Scheifele and Gordean L. Ginter and Edna Olsen and Susan Fussell and Margaret Pendray

DOI: 10.1093/jac/20.3.421

Statement on tetanus toxoid

CMAJ

Dixon, J.M.S. and Acres, S.E. and Ahronheim, G. and Carlson, J.A.K. and Delage, G. and Furesz, J. and Gold, R. and Hammond, G. and Ozere, R.L. and Scheifele, D.W. and Spence, L.P. and Tamblyn, S.E.

Rapid postmortem gut autolysis in infant rats: a potential problem for investigators.

Canadian journal of veterinary research = Revue canadienne de recherche vtrinaire

Scheifele, D. and Bjornson, G. and Dimmick, J.

Early onset campylobacter sepsis in a neonate

Pediatric Infectious Disease Journal

Forbes, J.C. and Scheifele, D.W.

DOI: 10.1097/00006454-198705000-00021

Cerebral blood flow in experimental Haemophilus influenzae b meningitis

Pediatric Infectious Disease Journal

Smith, A.L. and Scheifele, D. and Daum, R. and Averill, D. and Syriopolou, V.

DOI: 10.1097/00006454-198712000-00034

Delta-like toxin produced by coagulase-negative staphylococci is associated with neonatal necrotizing enterocolitis

Infection and Immunity

Scheifele, D.W. and Bjornson, G.L. and Dyer, R. and Dimmick, J.E.

Hepatitis B: Update on perinatal management

Canadian Medical Association Journal

Scheifele, D.W. and Hunter, M.I. and Bortolussi, R.A.

Initial antibiotic treatment of bacterial meningitis in children

Canadian Medical Association Journal

Gold, R. and Hunter, M.I. and Scheifele, D.W.

Serious Pasteurella multocida infections from lion and tiger bites.

JAMA

DOI: 10.1001/jama.1985.03350460096030 PubMed: 3999316

06 / 1985

Lack of nosocomial spread of Varicella in a pediatric hospital with negative pressure ventilated patient rooms.

Infection control : IC

PubMed: 3845064

03 / 1985

Endotoxinemia and Thrombocytopenia during Neonatal Necrotizing Enterocolitis

American Journal of Clinical Pathology

David W. Scheifele and Edna M. Olsen and Margaret R. Pendray

DOI: 10.1093/ajcp/83.2.227

02 / 1985

Spontaneous Endotoxinemia in Premature Infants

Journal of Pediatric Gastroenterology and Nutrition

David W. Scheifele and Edna Olsen and Susan Fussell and Margaret Pendray

DOI: 10.1097/00005176-198502000-00013

02 / 1985

Spontaneous endotoxinemia in premature infants: correlations with oral feeding and bowel dysfunction.

Journal of pediatric gastroenterology and nutrition

PubMed: 3981371

02 / 1985

Animal bites causing central nervous system injury in children. A report of three cases

Pediatric Neuroscience

Steinbok, P. and Flodmark, O. and Scheifele, D.W.

Pediculosis capitis (head lice)

Canadian Medical Association Journal

Scheifele, D.W. and Hunter, M.I. and Bortolussi, R.A.

Lack of nosocomial spread of Varicella in a pediatric hospital with negative pressure ventilated patient rooms

Infection Control

Anderson, J.D. and Bonner, M. and Scheifele, D.W. and Schneider, B.C.

DOI: 10.1017/S0195941700062792

Amoxicillin-clavulanate (Clavulin)

Canadian Medical Association Journal

Scheifele, D.W. and Hunter, M.I. and Bortolussi, R.A.

Animal bites causing central nervous system injury in children. A report of three cases.

Pediatric neuroscience

PubMed: 3837882

Evaluation of Skin Antisepsis Prior to Blood Culture in Neonates

Infection Control

Sylvie Champagne and Susan Fussell and David Scheifele

DOI: 10.1017/s0195941700060902

10 / 1984

Odontogenic infections

The Pediatric Infectious Disease Journal

DAVID W. MEGRAN and DAVID W. SCHEIFELE and ANTHONY W. CHOW

DOI: 10.1097/00006454-198405000-00018

05 / 1984

Variant postpartum toxic shock syndrome with probable intrapartum transmission to the neonate.

American journal of obstetrics and gynecology

DOI: 10.1016/s0002-9378(84)90448-4 PubMed: 6711641

04 / 1984

Bacterial Endotoxins in Umbilical Cord Blood of Neonates

Neonatology

David W. Scheifele and Susan Fussell and Edna Olsen

DOI: 10.1159/000241885

Cefuroxime in pediatric practice

Canadian Medical Association Journal

Scheifele, D. and Bortolussi, R. and Gold, R.

Cytomegalovirus: An occupational hazard?

Canadian Medical Association Journal

Scheifele, D. and Bortolussi, R. and Gold, R.

Acyclovir for intravenous use

Canadian Medical Association Journal

Scheifele, D.

Bacterial endotoxins in umbilical cord blood of neonates.

Biology of the neonate

PubMed: 6367839

Odontogenic infections.

Pediatric infectious disease

PubMed: 6377257

Potential significance of colonization with beta-lactamase-producing Haemophilus parainfluenzae in children.

European journal of clinical microbiology

DOI: 10.1007/bf02029515 PubMed: 6349987

06 / 1983

Recommendations for prevention of neonatal ophthalmia

Canadian Medical Association Journal

Scheifele, D.W. and Clogg, D. and Bortolussi, R.

Prophylactic antibiotics in children

The Pediatric Infectious Disease Journal

DAVID W. SCHEIFELE

DOI: 10.1097/00006454-198211000-00013

11 / 1982

Update on antibiotic resistance of Haemophilus influenzae in Canada.

Canadian Medical Association journal

PubMed: 6980695

08 / 1982

Characterization of ampicillin-resistant Haemophilus parainfluenzae.

Antimicrobial agents and chemotherapy

DOI: 10.1128/aac.21.5.734 PubMed: 6980626

05 / 1982

Update on antibiotic resistance of Haemophilus influenzae in Canada

Canadian Medical Association Journal

Scheifele, D.W.

Prophylactic antibiotics in children.

Pediatric infectious disease

PubMed: 6761659

Advantage of latex agglutination over countercurrent immunoelectrophoresis in the detection of Haemophilus influenzae type b antigen in serum.

Pediatrics

PubMed: 6976554

12 / 1981

Evaluation of the Limulus test for endotoxemia in neonates with suspected sepsis

The Journal of Pediatrics

David W. Scheifele and Patrick Melton and Valerie Whitchelo

DOI: 10.1016/s0022-3476(81)80582-3

06 / 1981

Ampicillin-Resistant Haemophilus influenzae Colonizing Ambulatory Children

American Journal of Diseases of Children

David W. Scheifele

DOI: 10.1001/archpedi.1981.02130290004002

05 / 1981

Ampicillin-resistant Haemophilus influenzae colonizing ambulatory children.

American journal of diseases of children (1960)

PubMed: 6972159

05 / 1981

Loss of plasmid DNA coding for beta-lactamase during experimental infection with Haemophilus influenzae type b.

The Journal of infectious diseases

DOI: 10.1093/infdis/143.4.548 PubMed: 6972420

04 / 1981

Frequency of ampicillin-resistant Haemophilus parainfluenzae in children.

The Journal of infectious diseases

DOI: 10.1093/infdis/143.3.495 PubMed: 6785367

03 / 1981

Endotoxinaemia per se as cause of neonatal morbidity.

Lancet (London, England)

DOI: 10.1016/s0140-6736(81)91962-0 PubMed: 6109984

02 / 1981

Advantage of latex agglutination over countercurrent immunoelectrophoresis in the detection of Haemophilus influenzae type b antigen in serum

Pediatrics

Scheifele, D.W. and Ward, J.I. and Siber, G.R.

Prevention and treatment of influenza A with amantadine hydrochloride.

Canadian Medical Association journal

PubMed: 7448670

11 / 1980

Streptococcal neonatal osteomyelitis.

American journal of diseases of children (1960)

PubMed: 6994488

07 / 1980

Airborne transmission of chickenpox.

The New England journal of medicine

PubMed: 7383115

07 / 1980

Haemophilus influenzae bacteremia and meningitis in infant primates.

The Journal of laboratory and clinical medicine

PubMed: 6766493

03 / 1980

Airborne Transmission of Chickenpox

New England Journal of Medicine

Riley, R.L. and Scheifele, D. and Bonner, M. and Leclair, J.M. and Zaia, J.A. and Levin, M.J. and Congdon, R.G. and Goldman, D.A.

DOI: 10.1056/NEJM198007313030513

Streptococcal Neonatal Osteomyelitis

American Journal of Diseases of Children

Lai, T.K. and Hingston, J. and Scheifele, D.

DOI: 10.1001/archpedi.1980.02130190077025

Prevention and treatment of influenza A with amantadine hydrochloride

Canadian Medical Association Journal

Junker, A. and Scheifele, D.

Haemophilus influenzae bacteremia and meningitis in infant primates

The Journal of Laboratory and Clinical Medicine

Scheifele, D.W. and Daum, R.S. and Syriopoulou, V.P. and Averill, D.R. and Smith, A.L.

Comparison of two antigen detection techniques in a primate model of Haemophilus influenzae type b infection.

Infection and immunity

PubMed: 118934

12 / 1979

Effect of inoculum size on the susceptibility of Haemophilus influenzae b to beta-lactam antibiotics.

Antimicrobial agents and chemotherapy

DOI: 10.1128/aac.16.4.510 PubMed: 316308

10 / 1979

Ampicillin-resistant Hemophilus influenzae in Canada: nationwide survey of hospital laboratories.

Canadian Medical Association journal

PubMed: 316354

07 / 1979

Ampicillin-resistant Hemophilus influenzae in Canada: Nationwide survey of hospital laboratories

Canadian Medical Association Journal

Scheifele, D.W.

Comparison of two antigen detection techniques in a primate model of Haemophilus influenzae type b infection

Infection and Immunity

Scheifele, D.W. and Daum, R.S. and Syriopoulou, V.P. and Siber, G.R. and Smith, A.L.

DOI: 10.1128/iai.26.3.827-831.1979

Rapid diagnosis of Hemophilus influenzae type b infections by latex particle agglutination and counterimmunoelectrophoresis

The Journal of Pediatrics

Joel I. Ward and George R. Siber and David W. Scheifele and David H. Smith

DOI: 10.1016/s0022-3476(78)80596-4

07 / 1978

Increasing incidence of ampicillin resistance in Hemophilus influenzae

The Journal of Pediatrics

Vassiliki Syriopoulou and David Scheifele and Arnold L. Smith and Patricia M. Perry and Virgil Howie

DOI: 10.1016/s0022-3476(78)80354-0

06 / 1978

Home-Testing for Recurrent Bacteriuria, Using Nitrite Strips

Archives of Pediatrics & Adolescent Medicine

David W. Scheifele

DOI: 10.1001/archpedi.1978.02120260048013

01 / 1978

Home-testing for recurrent bacteriuria, using nitrite strips.

American journal of diseases of children (1960)

PubMed: 623064

01 / 1978

Ventricular involvement in experimental Hemophilus influenzae meningitis

The Journal of Pediatrics

Robert S. Daum and David W. Scheifele and Vassiliki Ph. Syriopoulou and Damon Averill and Arnold L. Smith

DOI: 10.1016/s0022-3476(78)81213-x

RAPID DIAGNOSIS OF H. INFLUENZAE TYPE B (HIB) INFECTIONS BY LATEX PARTICLE AGGLUTINATION (LPA) AND COUNTER IMMUNOELECTROPHORESIS (CIE)

Pediatric Research

Joel I Ward and George R Siber and David W Scheifele and David H Smith

DOI: 10.1203/00006450-197704000-00834

04 / 1977

Incidence of ampicillin-resistant Hemophilus influenzae in otitis media

The Journal of Pediatrics

Vassiliki Syriopoulou and David Scheifele and Virgil Howie and John Ploussard and John Sloyer and Arnold L. Smith

DOI: 10.1016/s0022-3476(76)80821-9

11 / 1976

Evaluation of a rapid beta-lactamase test for detecting ampicillin-resistant strains of Hemophilus influenzae type b.

Pediatrics

PubMed: 1085435

09 / 1976

Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae

The Journal of Pediatrics

Paul A. Shurin and Stephen I. Pelton and David Scheifele and Jerome O. Klein

DOI: 10.1016/s0022-3476(76)80028-5

04 / 1976

Evaluation of a rapid lactamase test for detecting ampicillin resistant strains of Hemophilus influenzae type b

Pediatrics

Scheifele, D.W. and Syriopoulou, V.P. and Harding, A.L. and Emerson, B.B. and Smith, A.L.

Current concepts. The biology of measles in African children.

East African medical journal

PubMed: 4724680

03 / 1973

The management of measles in Nairobi.

East African medical journal

PubMed: 4724679

03 / 1973

The management of measles in Nairobi

East African Medical Journal

Forbes, C.E. and Scheifele, D.W.

The biology of measles in African children

East African Medical Journal

Scheifele, D.W. and Forbes, C.E.

Prolonged giant cell excretion in severe African measles.

Pediatrics

PubMed: 4636453

12 / 1972

Epidemiology of Meningococcal Disease in North America

Meningococcal Disease

Andrew J. Pollard and David Scheifele and Nancy Rosenstein

DOI: 10.1385/1-59259-149-3:341

Current Projects

I am the data centre supervisor for the Immunization Monitoring Program, Active (IMPACT), an active surveillance program involving 12 pediatric centers across Canada. This project is funded by the Public Health Agency of Canada and operated by the Canadian Pediatric Society and its specialist members in infectious diseases. Nurse monitors at each hospital actively search for admissions with adverse events following immunization, to assess causes and outcomes. This is a key means of assessing vaccine safety, particularly the occurrence of uncommon, severe reactions. Monitors also report on selected vaccine preventable diseases, as a measure of vaccine program effectiveness. Surveillance presently includes varicella, pertussis, invasive pneumococcal, meningococcal rotavirus and influenza admissions.

I was co-leader of the PHAC/CIHR Influenza Research Network (PCIRN), responsible for the Clinical Trials activities. PCIRN was established in April 2009 to prepare for necessary investigations during an influenza pandemic and was quickly re-tasked in May 2009 to focus on the H1N1 pandemic. The PCIRN network carried out 4 trials of pH1N1 vaccine in late 2009 involving over 700 subjects at 13 centers across Canada. Related studies continued in 2010 and 2011, the legacy from which will be an advanced state of preparedness for studies in a public health emergency.

Honours & Awards

Officer of the Order of Canada – 2013

Queen Elizabeth II Golden Jubilee Medal – 2013

Our Research

At BC Children’s, we are making discoveries that save lives and transform health care for children in our province and around the world. Our research portfolio includes basic, clinical, population, and public health research.

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BC Children's Hospital Research Institute operates on the ancestral and unceded territory of the Coast Salish peoples — xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh (Squamish), and Səl̓ílwətaʔ/Selilwitulh (Tsleil-Waututh) Nations. Further, this acknowledgement, gratitude, and respect extends to all of the First Nations communities on whose territories the Research Institute builds relationships and operates in British Columbia.

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