BCCHR Researchers Find a Researcher

George Sandor

MBBCH, FRCPC

Investigator, BC Children's Hospital

My area of research is congenital heart disease. The focus is a) the use of echocardiography to assess cardiac and vascular function with and without exercise and also b) fetal echocardiography.

Academic Affiliations

Professor Emeritus/a, Division of Cardiology, Department of Pediatrics, Faculty of Medicine, University of British Columbia
Research Theme: Childhood Diseases
Research Group(s): Clinical Practice, Outcomes and Innovation; Origins of Child Health and Disease; Rare Diseases

Contact Information

Location

4480 Oak St, Vancouver, BC, Canada, V6H 3V4

(604) 875-2954

gsandor@cw.bc.ca

Stress Echocardiographic Evaluation for D-Transposition of the Great Arteries after Atrial Redirection: Unmasking Early Signs of Myocardial Dysfunction and Baffle Stenosis.

Dvir-Orgad M and Anand M and De Souza AM and Zadorsky MT and Kiess MC and Potts JE and Sandor GG

DOI: 10.1016/j.echo.2016.09.005 PubMed: 28341033

01 / 2017

Echocardiographic Tests of Left Ventricular Function in Pediatric Cardiology: Are We Searching for the Holy Grail?

Sandor GG

DOI: 10.1016/j.cjca.2015.10.031 PubMed: 26922289

10 / 2016

Noninvasive Assessment of Vascular Function in Postoperative Cardiovascular Disease (Coarctation of the Aorta, Tetralogy of Fallot, and Transposition of the Great Arteries).

Mivelaz Y and Leung MT and Zadorsky MT and De Souza AM and Potts JE and Sandor GG

DOI: 10.1016/j.amjcard.2016.05.055 PubMed: 27401272

08 / 2016

Characterization of Myocardial Repolarization Reserve in Adolescent Females With Anorexia Nervosa.

Padfield GJ and Escudero CA and DeSouza AM and Steinberg C and Gibbs K and Puyat JH and Lam PY and Sanatani S and Sherwin E and Potts JE and Sandor G and Krahn AD

DOI: 10.1161/circulationaha.115.016697 PubMed: 26769740

02 / 2016

An Echocardiographic Study of Left Ventricular Size and Cardiac Function in Adolescent Females with Anorexia Nervosa.

Escudero CA and Potts JE and Lam PY and De Souza AM and Mugford GJ and Sandor GG

DOI: 10.1002/erv.2409 PubMed: 26449643

01 / 2016

Aortic and Cardiac Structure and Function Using High-Resolution Echocardiography and Optical Coherence Tomography in a Mouse Model of Marfan Syndrome.

Lee L and Cui JZ and Cua M and Esfandiarei M and Sheng X and Chui WA and Xu MH and Sarunic MV and Beg MF and van Breemen C and Sandor GG and Tibbits GF

DOI: 10.1371/journal.pone.0164778 PubMed: 27824871

Design and rationale of a prospective, collaborative meta-analysis of all randomized controlled trials of angiotensin receptor antagonists in Marfan syndrome, based on individual patient data: A report from the Marfan Treatment Trialists' Collaboration.

Pitcher A and Emberson J and Lacro RV and Sleeper LA and Stylianou M and Mahony L and Pearson GD and Groenink M and Mulder BJ and Zwinderman AH and De Backer J and De Paepe AM and Arbustini E and Erdem G and Jin XY and Flather MD and Mullen MJ and Child AH and Forteza A and Evangelista A

DOI: 10.1016/j.ahj.2015.01.011 PubMed: 25965707

05 / 2015

Obesity and arterial stiffness in children: systematic review and meta-analysis.

Cote AT and Phillips AA and Harris KC and Sandor GG and Panagiotopoulos C and Devlin AM

DOI: 10.1161/atvbaha.114.305062 PubMed: 25633314

04 / 2015

A randomized, double blind pilot study to assess the effects of losartan vs. atenolol on the biophysical properties of the aorta in patients with Marfan and Loeys-Dietz syndromes.

Sandor GG and Alghamdi MH and Raffin LA and Potts MT and Williams LD and Potts JE and Kiess M and van Breemen C

DOI: 10.1016/j.ijcard.2014.11.082 PubMed: 25465809

01 / 2015

Genetic variants in SLC22A17 and SLC22A7 are associated with anthracycline-induced cardiotoxicity in children.

Visscher H and Rassekh SR and Sandor GS and Caron HN and van Dalen EC and Kremer LC and van der Pal HJ and Rogers PC and Rieder MJ and Carleton BC and Hayden MR and Ross CJ and CPNDS consortium

DOI: 10.2217/pgs.15.61 PubMed: 26230641

Response to: echocardiography assessment of the aorta in children with chronic kidney disease.

Alghamdi M and De Souza AM and White CT and Potts MT and Warady BA and Furth SL and Kimball TR and Potts JE and Sandor GG

DOI: 10.1007/s00246-013-0776-3 PubMed: 24551878

01 / 2014

Childhood obesity and cardiovascular dysfunction.

Cote AT and Harris KC and Panagiotopoulos C and Sandor GG and Devlin AM

DOI: 10.1016/j.jacc.2013.07.042 PubMed: 23954339

10 / 2013

Noninvasive assessment of vascular function and hydraulic power and efficiency in pediatric Fontan patients.

Myers KA and Leung MT and Terri Potts M and Potts JE and Sandor GG

DOI: 10.1016/j.echo.2013.06.013 PubMed: 23860097

10 / 2013

Echo-Doppler assessment of arterial stiffness in pediatric patients with Kawasaki disease.

AlHuzaimi A and Al Mashham Y and Potts JE and De Souza AM and Sandor GG

DOI: 10.1016/j.echo.2013.05.015 PubMed: 23800509

09 / 2013

Physical activity recommendations for patients with electrophysiologic and structural congenital heart disease: a survey of Canadian health care providers.

Roston TM and De Souza AM and Sandor GG and Sanatani S and Potts JE

DOI: 10.1007/s00246-013-0654-z PubMed: 23435716

08 / 2013

Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children.

Visscher H and Ross CJ and Rassekh SR and Sandor GS and Caron HN and van Dalen EC and Kremer LC and van der Pal HJ and Rogers PC and Rieder MJ and Carleton BC and Hayden MR and CPNDS Consortium

DOI: 10.1002/pbc.24505 PubMed: 23441093

08 / 2013

Echo-Doppler assessment of the biophysical properties of the aorta in children with chronic kidney disease.

Alghamdi M and De Souza AM and White CT and Potts MT and Warady BA and Furth SL and Kimball TR and Potts JE and Sandor GG

DOI: 10.1007/s00246-013-0632-5 PubMed: 23381174

06 / 2013

Anthracycline induced cardiac toxicity in pediatric Ewing sarcoma: a longitudinal study.

Brown TR and Vijarnsorn C and Potts J and Milner R and Sandor GG and Fryer C

DOI: 10.1002/pbc.24404 PubMed: 23382019

05 / 2013

Postnatal outcome in patients with fetal tachycardia.

Moodley S and Sanatani S and Potts JE and Sandor GG

DOI: 10.1007/s00246-012-0392-7 PubMed: 22639009

01 / 2013

Population-based review of tetralogy of Fallot with absent pulmonary valve: is prenatal diagnosis really associated with a poor prognosis?

Mivelaz Y and Lim KI and Templeton C and Campbell AI and Potts JE and Sandor GG

DOI: 10.1002/uog.11126 PubMed: 22302386

11 / 2012

Biophysical properties of the aorta and left ventricle and exercise capacity in obese children.

Harris KC and Al Saloos HA and De Souza AM and Sanatani S and Hinchliffe M and Potts JE and Sandor GG

DOI: 10.1016/j.amjcard.2012.05.019 PubMed: 22728002

09 / 2012

Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children.

Visscher H and Ross CJ and Rassekh SR and Barhdadi A and Dub MP and Al-Saloos H and Sandor GS and Caron HN and van Dalen EC and Kremer LC and van der Pal HJ and Brown AM and Rogers PC and Phillips MS and Rieder MJ and Carleton BC and Hayden MR and Canadian Pharmacogenomics Network for Drug Safety Consortium

DOI: 10.1200/jco.2010.34.3467 PubMed: 21900104

05 / 2012

Balloon angioplasty for congenital aortic valve stenosis.

Sandor GG and Human DG and Potts JE

DOI: 10.1016/j.amjcard.2012.02.036 PubMed: 22546211

05 / 2012

Exercise-induced intrapulmonary arteriovenous shunt in healthy women.

Kennedy JM and Foster GE and Koehle MS and Potts JE and Sandor GG and Potts MT and Houghton KM and Henderson WR and Sheel AW

DOI: 10.1016/j.resp.2012.01.004 PubMed: 22285797

04 / 2012

An unusual case of cyanosis in right ventricular dysplasia in a child.

Dhillon SS and Duncan WJ and Harris KC and Sandor GG

DOI: 10.1016/j.jacc.2011.07.057 PubMed: 22361406

02 / 2012

Successful treatment of acute lymphoblastic leukemia in a child with trisomy 21 and complex congenital heart disease with mechanical prosthetic valve.

Alvi S and Shereck E and Heran MK and Sandor GG and Rassekh SR

DOI: 10.1155/2012/193093 PubMed: 23082266

Serial measurements of exercise performance in pediatric heart transplant patients using stress echocardiography.

Yeung JP and Human DG and Sandor GG and De Souza AM and Potts JE

DOI: 10.1111/j.1399-3046.2010.01467.x PubMed: 21492351

05 / 2011

Primary pulmonary arterial hypertension and autoimmune polyendocrine syndrome in a pediatric patient.

Alghamdi MH and Steinraths M and Panagiotopoulos C and Potts JE and Sandor GG

DOI: 10.1007/s00246-010-9704-y PubMed: 20411253

08 / 2010

Early changes in the biophysical properties of the aorta in pre-adolescent children born small for gestational age.

Bradley TJ and Potts JE and Lee SK and Potts MT and De Souza AM and Sandor GG

DOI: 10.1016/j.jpeds.2009.10.002 PubMed: 19939406

03 / 2010

Does biventricular pacing improve hemodynamics in children undergoing routine congenital heart surgery?

Jeewa A and Pitfield AF and Potts JE and Soulikias W and DeSouza ES and Hollinger AJ and Sandor GG and LeBlanc JG and Campbell AM and Sanatani S

DOI: 10.1007/s00246-009-9581-4 PubMed: 19936587

02 / 2010

Facilitated cardiac recovery in fulminant myocarditis: pediatric use of the Impella LP 5.0 pump.

Andrade JG and Al-Saloos H and Jeewa A and Sandor GG and Cheung A

DOI: 10.1016/j.healun.2009.06.020 PubMed: 19782584

01 / 2010

Abnormal flow in the posterior descending artery: an echo Doppler clue to the anomalous origin of left anterior descending coronary artery from the pulmonary trunk.

Myers KA and Potts MT and Sandor GG

DOI: 10.1007/s00246-009-9388-3 PubMed: 19225829

05 / 2009

A novel method to estimate the aortic pressure waveform using B-mode ultrasound images acquired from a suprasternal view.

Leung MT and Dumont GA and Sandor GG and Potts M and Potts JE

DOI: 10.1109/iembs.2008.4650407 PubMed: 19163910

Echocardiographic Doppler demonstrates increasing aortic pulse wave velocity (PWV) in adult patients with renal disease.

Sandor GG and Potts JE and Bradley TJ

DOI: 10.1016/j.echo.2007.06.008 PubMed: 17681727

10 / 2007

Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.

Chung AW and Au Yeung K and Sandor GG and Judge DP and Dietz HC and van Breemen C

DOI: 10.1161/circresaha.107.157776 PubMed: 17641224

08 / 2007

A population-based study of cardiac malformations and outcomes associated with dextrocardia.

Bohun CM and Potts JE and Casey BM and Sandor GG

DOI: 10.1016/j.amjcard.2007.02.095 PubMed: 17631088

07 / 2007

A stress echocardiography study of cardiac function during progressive exercise in pediatric oncology patients treated with anthracyclines.

De Souza AM and Potts JE and Potts MT and De Souza ES and Rowland TW and Pritchard SL and Sandor GG

DOI: 10.1002/pbc.21122 PubMed: 17226848

07 / 2007

Endothelial dysfunction and compromised eNOS/Akt signaling in the thoracic aorta during the progression of Marfan syndrome.

Chung AW and Au Yeung K and Cortes SF and Sandor GG and Judge DP and Dietz HC and van Breemen C

DOI: 10.1038/sj.bjp.0707181 PubMed: 17339838

04 / 2007

Device closure of a secundum atrial septal defect in a 4-month-old infant with a marginal left ventricle following coarctation repair.

Jean-St-Michel E and Hosking MC and Potts JE and Sandor GG

DOI: 10.1111/j.1747-0803.2007.00140.x PubMed: 18377440

Exercise does not cause an arm-leg blood pressure gradient in healthy children.

Young CE and Sandor GG and Potts JE

DOI: 10.1136/hrt.2005.084384 PubMed: 16644859

11 / 2006

Intra-atrial thrombus in a neonate with coarctation of the aorta.

Al Dhahri KN and Sandor GG and Duncan WJ

DOI: 10.1017/s1047951106000436 PubMed: 16839432

08 / 2006

Right-sided cardiac involvement in osteogenesis imperfecta.

Khashu M and Pelligra G and Sandor GG and Singh AJ

PubMed: 16901059

07 / 2006

Is the nuchal index increased in fetuses with congenital structural heart defects?

Dahlgren LS and Duncan WJ and Farquarhson DF and Sandor GS and Skoll MA and Tessier F and Lim KI

DOI: 10.1159/000089057 PubMed: 16354985

Estimating arterial stiffness using transmission line model.

Leung M and Dumont G and Sandor GS and Potts JE

DOI: 10.1109/iembs.2006.260616 PubMed: 17946459

Echocardiographic Doppler assessment of the biophysical properties of the aorta in pediatric patients with the Marfan syndrome.

Bradley TJ and Potts JE and Potts MT and DeSouza AM and Sandor GG

DOI: 10.1016/j.amjcard.2005.06.080 PubMed: 16253606

11 / 2005

Diagnosis of fetal ductus arteriosus aneurysm: importance of the three-vessel view.

Jackson CM and Sandor GG and Lim K and Duncan WJ and Potts JE

DOI: 10.1002/uog.1927 PubMed: 15971287

07 / 2005

Repair in infancy of right aortic arch with aberrant left brachiocephalic artery in the setting of a variant of the hypoplastic left heart syndrome.

Sett SS and Mawson JB and Sandor GG

DOI: 10.1017/s1047951104004147 PubMed: 15680052

08 / 2004

Diagnosis and outcome of dextrocardia diagnosed in the fetus.

Walmsley R and Hishitani T and Sandor GG and Lim K and Duncan W and Tessier F and Farquharson DF and Potts JE

DOI: 10.1016/j.amjcard.2004.03.049 PubMed: 15219529

07 / 2004

Pulmonary atresia with intact ventricular septum and antenatal left ventricular failure.

Khoshhal S and Sandor GG and Duncan WJ

DOI: 10.1017/s1047951104003178 PubMed: 15680033

06 / 2004

Isolated haemangioma of the tricuspid valve.

Wong KK and Sandor GG and Sett SS

DOI: 10.1017/s1047951104003129 PubMed: 15680028

06 / 2004

Myocardial contractility in premature neonates with and without patent ductus arteriosus.

Barlow AJ and Ward C and Webber SA and Sinclair BG and Potts JE and Sandor GG

DOI: 10.1007/s00246-003-0452-0 PubMed: 14648000

Parents' perspectives on decision making after antenatal diagnosis of congenital heart disease.

Rempel GR and Cender LM and Lynam MJ and Sandor GG and Farquharson D

DOI: 10.1177/0884217503261092 PubMed: 14971554

A novel Doppler echocardiographic method of measuring the biophysical properties of the aorta in pediatric patients.

Sandor GG and Hishitani T and Petty RE and Potts MT and Desouza A and Desouza E and Potts JE

DOI: 10.1016/s0894-7317(03)00407-3 PubMed: 12835661

07 / 2003

Coronary arterial abnormalities in pulmonary atresia with intact ventricular septum diagnosed during fetal life.

Sandor GG and Cook AC and Sharland GK and Ho SY and Potts JE and Anderson RH

DOI: 10.1017/s1047951102000756 PubMed: 15773446

10 / 2002

Pulmonary atresia with intact ventricular septum: range of morphology in a population-based study.

Daubeney PE and Delany DJ and Anderson RH and Sandor GG and Slavik Z and Keeton BR and Webber SA and United Kingdom and Ireland Collaborative Study of Pulmonary Atresia with Intact Ventricular Septum

DOI: 10.1016/s0735-1097(02)01832-6 PubMed: 12020496

05 / 2002

"Masked" pulmonary venous obstruction in patients with isomerism of the right atrial appendages: an overstated association.

Becket Mahnke C and Sandor GG and Boyle GJ and Webber SA

DOI: 10.1017/s1047951102000252 PubMed: 12018714

03 / 2002

Interrupted right aortic arch and origin of the left pulmonary artery from the aorta in DiGeorge syndrome.

Sett SS and Sandor GG and Mawson JB

DOI: 10.1017/s104795110100110x PubMed: 11813925

11 / 2001

Postpericardiotomy syndrome: no evidence for a viral etiology.

Webber SA and Wilson NJ and Junker AK and Byrne SK and Perry A and Thomas EE and Book L and Tipple M and Patterson MW and Sandor GG

DOI: 10.1017/s1047951100012440 PubMed: 11233400

01 / 2001

Balloon angioplasty of right ventricular outflow tract conduits.

Sanatani S and Potts JE and Human DG and Sandor GG and Patterson MW and Gordon Culham JA

DOI: 10.1007/s002460010209 PubMed: 11343149

Echocardiography and pulmonary function testing in childhood onset systemic lupus erythematosus.

Al-Abbad AJ and Cabral DA and Sanatani S and Sandor GG and Seear M and Petty RE and Malleson PN

DOI: 10.1191/096120301669980721 PubMed: 11243507

Cardiac responses to progressive exercise in normal children: a synthesis.

Rowland T and Potts J and Potts T and Sandor G and Goff D and Ferrone L

DOI: 10.1097/00005768-200002000-00001 PubMed: 10694103

02 / 2000

Coil occlusion of the patent ductus arteriosus: lessons learned.

Sanatani S and Potts JE and Ryan A and Sandor GG and Human DG and Culham JA

DOI: 10.1007/s002709910019 PubMed: 10795831

Outcome of fetuses diagnosed with atrioventricular septal defect.

Delisle MF and Sandor GG and Tessier F and Farquharson DF

DOI: 10.1016/s0029-7844(99)00389-0 PubMed: 10546725

11 / 1999

Cardiovascular responses to exercise in children and adolescents with myocardial dysfunction.

Rowland T and Potts J and Potts T and Son-Hing J and Harbison G and Sandor G

DOI: 10.1016/s0002-8703(99)70468-0 PubMed: 9878945

01 / 1999

Vascular abnormalities in Adams-Oliver syndrome: cause or effect?

Swartz EN and Sanatani S and Sandor GG and Schreiber RA

DOI: 10.1002/(sici)1096-8628(19990101)82:1u003C49::aid-ajmg10u003E3.0.co;2-m PubMed: 9916843

01 / 1999

[Standards of pediatric echocardiography]

Smallhorn JF and Fouron JC and Robertson MA and Sandor G

PubMed: 9738158

08 / 1998

Kawasaki disease in the older child.

Momenah T and Sanatani S and Potts J and Sandor GG and Human DG and Patterson MW

DOI: 10.1542/peds.102.1.e7 PubMed: 9651459

07 / 1998

Standards for training in pediatric echocardiography. Canadian Cardiovascular Society.

Fouron JC and Robertson MA and Sandor G

PubMed: 9706272

07 / 1998

Differences in dose scheduling as a factor in the etiology of anthracycline-induced cardiotoxicity in Ewing sarcoma patients.

Kakadekar AP and Sandor GG and Fryer C and Chan KW and Rogers PC and Pritchard S and Popov R

DOI: 10.1002/(sici)1096-911x(199701)28:1u003C22::aid-mpo5u003E3.0.co;2-v PubMed: 8950332

01 / 1997

Short- and long-term variability of echocardiographic stress-velocity indexes of cardiac function in a pediatric population.

Sandor GG and Webber SA and Popov RO and DeSouza E and Johnston B

DOI: 10.1016/s0894-7317(96)90137-6 PubMed: 8736007

Effectiveness of primary level antenatal screening for severe congenital heart disease: a population-based assessment.

Sinclair BG and Sandor GG and Farquharson DF

PubMed: 8915930

Influence of competitive pulmonary blood flow on the bidirectional superior cavopulmonary shunt. A multi-institutional study.

Webber SA and Horvath P and LeBlanc JG and Slavik Z and Lamb RK and Monro JL and Reich O and Hruda J and Sandor GG and Keeton BR

DOI: 10.1161/01.cir.92.9.279 PubMed: 7586424

11 / 1995

Pulmonary artery banding is not contraindicated in double inlet left ventricle with transposition and aortic arch obstruction.

Webber SA and LeBlanc JG and Keeton BR and Salmon AP and Sandor GG and Lamb RK and Monro JL

DOI: 10.1016/s1010-7940(95)80052-2 PubMed: 8800701

Role of transesophageal echocardiography in the management of aortic-left ventricular tunnel.

Kakadekar AP and Sandor GG and Patterson MW and LeBlanc JG

DOI: 10.1007/bf00801913 PubMed: 7617509

Guidelines for monitoring of anthracycline cardiomyopathy: a rebuttal.

Steinherz LJ and Graham T and Hurwitz R and Sondheimer HM and Schaffer EM and Schwartz RG and Sandor G and Benson L and Williams R

PubMed: 7936926

11 / 1994

Angiographic demonstration of endocardial fibroelastosis in an infant with critical aortic stenosis.

Ward CJ and Culham JA and Mawson J and Sandor GG

DOI: 10.1016/0002-8703(94)90071-x PubMed: 8172080

05 / 1994

Systolic and diastolic function in tricuspid valve atresia before the Fontan operation.

Sandor GG and Patterson MW and LeBlanc JG

DOI: 10.1016/0002-9149(94)90236-4 PubMed: 8296762

02 / 1994

Double-blind placebo-controlled trial of corticosteroids in children with postpericardiotomy syndrome.

Wilson NJ and Webber SA and Patterson MW and Sandor GG and Tipple M and LeBlanc J

PubMed: 7997415

Immunogenicity of Haemophilus influenzae type b conjugate vaccine in children with congenital asplenia.

Webber SA and Sandor GG and Patterson MW and Mitchell LA and Scheifele D and Ochnio JJ and McVerry PH

DOI: 10.1093/infdis/167.5.1210 PubMed: 8486956

05 / 1993

Pulmonary vascular disease in neonates with transposition of the great arteries and intact ventricular septum.

Kumar A and Taylor GP and Sandor GG and Patterson MW

DOI: 10.1136/hrt.69.5.442 PubMed: 8518068

05 / 1993

Pulmonary wedge angiography for prediction of pulmonary vascular disease in Down syndrome.

Wilson NJ and Culham JA and Sandor GG and Taylor GP

DOI: 10.1002/ccd.1810280106 PubMed: 8416328

01 / 1993

Autoantibody production after cardiopulmonary bypass with special reference to postpericardiotomy syndrome.

Webber SA and Wilson NJ and Fung MY and Malleson PN and Petty RE and Patterson MW and Sandor GG

DOI: 10.1016/s0022-3476(05)81907-9 PubMed: 1432426

11 / 1992

Doppler echocardiographic observations of diastolic trans-septal flow through small ventricular septal defects.

Webber SA and Sandor GG and Patterson MW

DOI: 10.1093/oxfordjournals.eurheartj.a060229 PubMed: 1618207

05 / 1992

Guidelines for cardiac monitoring of children during and after anthracycline therapy: report of the Cardiology Committee of the Childrens Cancer Study Group.

Steinherz LJ and Graham T and Hurwitz R and Sondheimer HM and Schwartz RG and Shaffer EM and Sandor G and Benson L and Williams R

PubMed: 1579408

05 / 1992

Early prediction of anthracycline cardiomyopathy using standard M-mode and digitized echocardiography.

Sandor GG and Puterman M and Rogers P and Chan KW and Pritchard S and Popov R

PubMed: 1530119

05 / 1992

Rate-corrected mean velocity of fiber shortening-stress at peak systole as a load-independent measure of contractility.

Sandor GG and Popov R and De Souza E and Morris S and Johnston B

DOI: 10.1016/0002-9149(92)90242-q PubMed: 1734656

02 / 1992

Efficacy and safety of oral sotalol in early infancy.

Tipple M and Sandor G

DOI: 10.1111/j.1540-8159.1991.tb02816.x PubMed: 1721225

11 / 1991

Doppler-derived mean aortic flow velocity in children: an alternative to cardiac index.

Seear MD and D'Orsogna L and Sandor GG and de Souza E and Popov R

DOI: 10.1007/bf02310565 PubMed: 1946006

10 / 1991

Balloon dilatation of restrictive interatrial communications in congenital heart disease.

Webber SA and Culham JA and Sandor GG and Patterson MW

DOI: 10.1136/hrt.65.6.346 PubMed: 2054246

06 / 1991

Congenital heart disease and Robinow syndrome: coincidence or an additional component of the syndrome?

Webber SA and Wargowski DS and Chitayat D and Sandor GG

DOI: 10.1002/ajmg.1320370418 PubMed: 2260599

12 / 1990

Successful treatment of a nondeflatable balloon atrial septostomy catheter.

Wilson NJ and Culham JA and Sandor GG

DOI: 10.1007/bf02238846 PubMed: 2395743

07 / 1990

Optimal choice of prognostic variables with an application to cardiac monitoring using M-mode echocardiography.

Puterman ML and Schumacher P and Sandor GG

DOI: 10.1002/sim.4780090310 PubMed: 2188326

03 / 1990

The clinical value and risks of lung biopsy in children with congenital heart disease.

Wilson NJ and Seear MD and Taylor GP and LeBlanc JG and Sandor GG

PubMed: 2106601

03 / 1990

Assessment of bedside umbilical vein balloon septostomy using two-dimensional echocardiographic guidance in transposition of great arteries.

D'Orsogna L and Lam J and Sandor GG and Patterson MW

DOI: 10.1016/0167-5273(89)90217-9 PubMed: 2613374

12 / 1989

Influence of echocardiography in pre-operative cardiac catheterization in congenital heart disease.

D'Orsogna L and Sandor GG and Patterson MW and Ashmore PG and LeBlanc J and Culham JA

DOI: 10.1016/0167-5273(89)90036-3 PubMed: 2759753

07 / 1989

Role of prenatal detection of cardiac tumours in the diagnosis of tuberous sclerosis--report of two cases.

Chitayat D and McGillivray BC and Diamant S and Wittmann BK and Sandor GG

DOI: 10.1002/pd.1970080805 PubMed: 3060871

10 / 1988

Left ventricular systolic and diastolic function after two-stage anatomic correction of transposition of the great arteries.

Sandor GS and Freedom RM and Williams WG and LeBlanc J and Trusler G and Patterson MW and Ashmore PG

DOI: 10.1016/0002-8703(88)90018-x PubMed: 3376844

06 / 1988

Pulmonary artery banding: results and current indications in pediatric cardiac surgery.

LeBlanc JG and Ashmore PG and Pineda E and Sandor GG and Patterson MW and Tipple M

DOI: 10.1016/s0003-4975(10)62150-9 PubMed: 2446573

12 / 1987

Left ventricular systolic and diastolic function after total correction of tetralogy of Fallot.

Sandor GG and Patterson MW and Tipple M and Ashmore PG and Popov R

DOI: 10.1016/0002-9149(87)90408-5 PubMed: 3687744

11 / 1987

Successful balloon angioplasty of peripheral pulmonary stenosis in Williams syndrome.

D'Orsogna L and Sandor GG and Culham JA and Patterson M

DOI: 10.1016/0002-8703(87)90764-2 PubMed: 2957904

09 / 1987

Normal serial variability for M-mode and digitized echocardiography in a pediatric population.

Sandor GG and Schumacher P and Puterman ML and Popov R

DOI: 10.1007/bf02308380 PubMed: 3601733

Effect of pressure loading, volume loading and surgery on left ventricular chamber and myocardial stiffness in congenital heart disease, with a reevaluation of normal pediatric values.

Sandor GG and Puterman ML and Patterson MW and Tipple MA and Vince DJ

DOI: 10.1016/s0735-1097(86)80053-5 PubMed: 3734258

08 / 1986

Treatment of grafts and major vessel thrombosis with low-dose streptokinase in children.

LeBlanc JG and Culham JA and Chan KW and Patterson MW and Tipple M and Sandor GG

DOI: 10.1016/s0003-4975(10)63077-9 PubMed: 3718040

06 / 1986

Fetal echocardiography: results in high-risk patients.

Sandor GG and Farquarson D and Wittmann B and Chow TC and Lau AE

PubMed: 3945447

03 / 1986

Cardiovascular therapy in the newborn.

Sandor GG

PubMed: 3907921

Clinical and echocardiographic evidence suggesting afterload reduction as a mechanism of action of tolazoline in neonatal hypoxemia.

Sandor GG and Macnab AJ and Akesode FA and Ebelt VJ and Pendray MR and Ling WY and Patterson MW and Tipple MA

DOI: 10.1007/bf02424957 PubMed: 6473128

Successful palliation by pulmonary artery banding in absent pulmonary valve syndrome with aneurysmal pulmonary arteries.

Opie JC and Sandor GG and Ashmore PG and Patterson MW

PubMed: 6184577

01 / 1983

Serum digoxin levels in neonates under 1500 grams.

Sandor GG and Reid G and Patterson MW

PubMed: 6646879

Determination of left ventricular diastolic chamber stiffness and myocardial stiffness in patients with congenital heart disease.

Sandor GG and Olley PM

DOI: 10.1016/0002-9149(82)91958-0 PubMed: 7064828

03 / 1982

Serum digoxin levels in neonates whose weights are less than 1,500 grams.

Patterson MW and Reid G and Sandor GG

PubMed: 7162876

The ECG in aortic stenosis. Value of TAVF and QV6.

Fowler RS and Wood MM and Bain H and Patel RG and Sandor GG and Rowe RD

DOI: 10.1007/bf02240455 PubMed: 7155959

Reliability of systolic time intervals in diagnosis of transposition of great arteries in newborn.

Sandor GG and Patterson MW and Tipple M and Vince DJ

DOI: 10.1136/hrt.46.1.74 PubMed: 7272116

07 / 1981

Intrinsic defects in the fetal alcohol syndrome: studies on 76 cases from British Columbia and the Yukon Territory.

Smith DF and Sandor GG and MacLeod PM and Tredwell S and Wood B and Newman DE

PubMed: 7195990

Long-term follow-up of patients after valvotomy for congenital valvular aortic stenosis in children: a clinical and actuarial follow-up.

Sandor GG and Olley PM and Trusler GA and Williams WG and Rowe RD and Morch JE

PubMed: 7401666

08 / 1980

Noninvasive assessment of left ventricular function related to serum digoxin levels in neonates.

Sandor GG and Bloom KR and Izukawa T and Patterson MW and Rowe RD

PubMed: 7360542

03 / 1980

Letter: Phototherapy and chromosome structure.

Sandor G

DOI: 10.1016/s0140-6736(73)93345-x PubMed: 4128071

12 / 1973

Premature rupture of membranes and effects of prophylactic antibiotics.

Habel AH and Sandor GS and Conn NK and McCrae WM

DOI: 10.1136/adc.47.253.401 PubMed: 4624593

06 / 1972

Fingerprint changes in coeliac disease.

McCrae WM and Sandor G and Sangani AP and Stalker R

DOI: 10.1136/bmj.3.5766.109-c PubMed: 5090799

07 / 1971

Current Projects

Structure and function of the heart can be examined using ultrasound. My interest lies in using the latest ultrasound to characterize the heart’s ability to pump and to fill. This work attempts to accurately assess and diagnose abnormalities of function early, and to compare the results of different types of medical and surgical treatment to evaluate outcome. Our laboratory has been a pioneer in the simplification of non-invasive methods of assessing heart function and we have also developed a new technique to quantify the properties of the major blood vessels coming from the heart to see whether these are diseased or healthy. We are also examining the interaction of heart function with the properties of the blood vessels to see how efficient the heart and circulation are. These types of studies are of importance in patients who have some compromise of cardiac function, so that therapy may be optimised to enable the heart to work most efficiently.

Our laboratory has devised a technique whereby the heart can be imaged with ultrasound during exercise and with this technique are able to obtain indexes of cardiac function, cardiac output and examine the heart muscle contractility using stage exercise. This technique is unique and has been extremely useful in assessing the cardiac reserve in patients for whom decisions have to be made with regard to surgery, continuing potentially cardiotoxic medications and assessing the effects of these. This has been found very helpful in situations where the examination of the heart at rest has not provided enough information about the potential heart to do exercise. In addition, this technique has been very helpful in unmasking a partial blockage in blood vessels whereby exercise increased the cardiac output and has demonstrated a significant degree of obstruction that is not apparent in the resting state. We have undertaken some of this work for the Adult Congenital Heart Disease Program.

The antenatal diagnosis of congenital heart disease continues to develop and we have been one of the first centers to institute a fetal cardiac diagnosis program. This is unique in that it integrates perinatology and the fetal diagnosis program, which help in the management of these difficult situations. In addition to evaluating the accuracy of this technique, we have also examined issues of outcomes, population statistics and just as importantly, a qualitative study of such diagnoses. We have also started to use an adaptation of the technique of assessment of the vascular properties by ultrasound (alluded to in the previous paragraphs) to attempt to assess fetal circulatory health, and we hope that this test will give us further insights into placental insufficiency and perhaps an earlier diagnosis of such problems.

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Congratulations CIHR Grant Recipients!
We are pleased to congratulate the BC Children's and BC Women's investigators who were awarded funding from the Canadian Institutes of Health Research (CIHR) Project Grant Spring 2018 competition, as well as the BC Children's investigators who received funding from the recent CIHR Foundation and Team Grant competitions.
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Our Research

At BC Children’s, we are making discoveries that save lives and transform health care for children in our province and around the world. Our research portfolio includes basic, clinical, population, and public health research.

EXPLORE OUR RESEARCH

George Sandor

MBBCH, FRCPC

Investigator, BC Children's Hospital

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Stress Echocardiographic Evaluation for D-Transposition of the Great Arteries after Atrial Redirection: Unmasking Early Signs of Myocardial Dysfunction and Baffle Stenosis.

Echocardiographic Tests of Left Ventricular Function in Pediatric Cardiology: Are We Searching for the Holy Grail?

Noninvasive Assessment of Vascular Function in Postoperative Cardiovascular Disease (Coarctation of the Aorta, Tetralogy of Fallot, and Transposition of the Great Arteries).

Characterization of Myocardial Repolarization Reserve in Adolescent Females With Anorexia Nervosa.

An Echocardiographic Study of Left Ventricular Size and Cardiac Function in Adolescent Females with Anorexia Nervosa.

Aortic and Cardiac Structure and Function Using High-Resolution Echocardiography and Optical Coherence Tomography in a Mouse Model of Marfan Syndrome.

Design and rationale of a prospective, collaborative meta-analysis of all randomized controlled trials of angiotensin receptor antagonists in Marfan syndrome, based on individual patient data: A report from the Marfan Treatment Trialists' Collaboration.

Obesity and arterial stiffness in children: systematic review and meta-analysis.

A randomized, double blind pilot study to assess the effects of losartan vs. atenolol on the biophysical properties of the aorta in patients with Marfan and Loeys-Dietz syndromes.

Genetic variants in SLC22A17 and SLC22A7 are associated with anthracycline-induced cardiotoxicity in children.

Response to: echocardiography assessment of the aorta in children with chronic kidney disease.

Childhood obesity and cardiovascular dysfunction.

Noninvasive assessment of vascular function and hydraulic power and efficiency in pediatric Fontan patients.

Echo-Doppler assessment of arterial stiffness in pediatric patients with Kawasaki disease.

Physical activity recommendations for patients with electrophysiologic and structural congenital heart disease: a survey of Canadian health care providers.

Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children.

Echo-Doppler assessment of the biophysical properties of the aorta in children with chronic kidney disease.

Anthracycline induced cardiac toxicity in pediatric Ewing sarcoma: a longitudinal study.

Postnatal outcome in patients with fetal tachycardia.

Population-based review of tetralogy of Fallot with absent pulmonary valve: is prenatal diagnosis really associated with a poor prognosis?

Biophysical properties of the aorta and left ventricle and exercise capacity in obese children.

Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children.

Balloon angioplasty for congenital aortic valve stenosis.

Exercise-induced intrapulmonary arteriovenous shunt in healthy women.

An unusual case of cyanosis in right ventricular dysplasia in a child.

Successful treatment of acute lymphoblastic leukemia in a child with trisomy 21 and complex congenital heart disease with mechanical prosthetic valve.

Serial measurements of exercise performance in pediatric heart transplant patients using stress echocardiography.

Primary pulmonary arterial hypertension and autoimmune polyendocrine syndrome in a pediatric patient.

Early changes in the biophysical properties of the aorta in pre-adolescent children born small for gestational age.

Does biventricular pacing improve hemodynamics in children undergoing routine congenital heart surgery?

Facilitated cardiac recovery in fulminant myocarditis: pediatric use of the Impella LP 5.0 pump.

Abnormal flow in the posterior descending artery: an echo Doppler clue to the anomalous origin of left anterior descending coronary artery from the pulmonary trunk.

A novel method to estimate the aortic pressure waveform using B-mode ultrasound images acquired from a suprasternal view.

Echocardiographic Doppler demonstrates increasing aortic pulse wave velocity (PWV) in adult patients with renal disease.

Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.

A population-based study of cardiac malformations and outcomes associated with dextrocardia.

A stress echocardiography study of cardiac function during progressive exercise in pediatric oncology patients treated with anthracyclines.

Endothelial dysfunction and compromised eNOS/Akt signaling in the thoracic aorta during the progression of Marfan syndrome.

Device closure of a secundum atrial septal defect in a 4-month-old infant with a marginal left ventricle following coarctation repair.

Exercise does not cause an arm-leg blood pressure gradient in healthy children.

Intra-atrial thrombus in a neonate with coarctation of the aorta.

Right-sided cardiac involvement in osteogenesis imperfecta.

Is the nuchal index increased in fetuses with congenital structural heart defects?

Estimating arterial stiffness using transmission line model.

Echocardiographic Doppler assessment of the biophysical properties of the aorta in pediatric patients with the Marfan syndrome.

Diagnosis of fetal ductus arteriosus aneurysm: importance of the three-vessel view.

Repair in infancy of right aortic arch with aberrant left brachiocephalic artery in the setting of a variant of the hypoplastic left heart syndrome.

Diagnosis and outcome of dextrocardia diagnosed in the fetus.

Pulmonary atresia with intact ventricular septum and antenatal left ventricular failure.

Isolated haemangioma of the tricuspid valve.

Myocardial contractility in premature neonates with and without patent ductus arteriosus.

Parents' perspectives on decision making after antenatal diagnosis of congenital heart disease.

A novel Doppler echocardiographic method of measuring the biophysical properties of the aorta in pediatric patients.

Coronary arterial abnormalities in pulmonary atresia with intact ventricular septum diagnosed during fetal life.

Pulmonary atresia with intact ventricular septum: range of morphology in a population-based study.

"Masked" pulmonary venous obstruction in patients with isomerism of the right atrial appendages: an overstated association.

Interrupted right aortic arch and origin of the left pulmonary artery from the aorta in DiGeorge syndrome.

Postpericardiotomy syndrome: no evidence for a viral etiology.

Balloon angioplasty of right ventricular outflow tract conduits.

Echocardiography and pulmonary function testing in childhood onset systemic lupus erythematosus.

Cardiac responses to progressive exercise in normal children: a synthesis.

Coil occlusion of the patent ductus arteriosus: lessons learned.

Outcome of fetuses diagnosed with atrioventricular septal defect.

Cardiovascular responses to exercise in children and adolescents with myocardial dysfunction.

Vascular abnormalities in Adams-Oliver syndrome: cause or effect?

[Standards of pediatric echocardiography]

Kawasaki disease in the older child.

Standards for training in pediatric echocardiography. Canadian Cardiovascular Society.

Differences in dose scheduling as a factor in the etiology of anthracycline-induced cardiotoxicity in Ewing sarcoma patients.

Short- and long-term variability of echocardiographic stress-velocity indexes of cardiac function in a pediatric population.

Effectiveness of primary level antenatal screening for severe congenital heart disease: a population-based assessment.