Overview

The aim of our research at the Vaccine Evaluation Center (VEC) is to lower the burden of childhood infectious disease through vaccination by building an evidence base for local, national and international vaccine policy. My research program includes laboratory studies to develop new and better vaccines, clinical trials to identify how best to utilize new and approved vaccines, and population-based investigations to identify targets for new vaccines and demonstrate vaccine impact.

Publications

Kawasaki disease following immunization reported to the Canadian Immunization Monitoring Program ACTive (IMPACT) from 2013 to 2018
Human Vaccines & Immunotherapeutics
Khaled Alsager and Nirma Khatri Vadlamudi and Taj Jadavji and Julie A. Bettinger and Cora Constantinescu and Wendry Vaudry and Ben Tan and Laura Sauvé and Manish Sadarangani and Scott A. Halperin and Karina A. Top
DOI: 10.1080/21645515.2022.2088215
07/2022

Vaccine regulation should require and enforce the inclusion of pregnant and breastfeeding women in prelicensure clinical trials
Human Vaccines & Immunotherapeutics
Terra A. Manca and Manish Sadarangani and Scott A. Halperin and Joanne M. Langley and Elisabeth McClymont and Shannon E. MacDonald and Karina A. Top
DOI: 10.1080/21645515.2022.2104019
07/2022

A Survey of Immunization Practices in Patients With Congenital Heart Disease
CJC Pediatric and Congenital Heart Disease
Gabrielle Sanatani and Sonia Franciosi and Jeffrey N. Bone and Brynn Dechert and Kevin C. Harris and Manish Sadarangani
DOI: 10.1016/j.cjcpc.2021.12.003
04/2022

Cutaneous CpG adjuvant conditioning to enhance vaccine responses
Vaccine
Douglas A. Carlow and Jacqueline C.Y. Lai and Tobias R. Kollmann and Manish Sadarangani and Jan P. Dutz
DOI: 10.1016/j.vaccine.2021.12.060
03/2022

Human B Cell Responses to Dominant and Subdominant Antigens Induced by a Meningococcal Outer Membrane Vesicle Vaccine in a Phase I Trial
mSphere
Christine S. Rollier and Christina Dold and Leanne Marsay and Aline Linder and Christopher A. Green and Manish Sadarangani and Gunnstein Norheim and Jeremy P. Derrick and Ian M. Feavers and Martin C. J. Maiden and Andrew J. Pollard
DOI: 10.1128/msphere.00674-21
02/2022

Impact of the COVID-19 pandemic on vaccine coverage for early childhood vaccines in Alberta, Canada: A population-based retrospective cohort study
BMJ Open
Macdonald, S.E. and Paudel, Y.R. and Kiely, M. and Rafferty, E. and Sadarangani, M. and Robinson, J.L. and Driedger, S.M. and Svenson, L.W.
DOI: 10.1136/bmjopen-2021-055968
2022

Single-dose mRNA Vaccine Effectiveness Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Including Alpha and Gamma Variants: A Test-negative Design in Adults 70 Years and Older in British Columbia, Canada
Clinical Infectious Diseases
Skowronski, D.M. and Setayeshgar, S. and Zou, M. and Prystajecky, N. and Tyson, J.R. and Galanis, E. and Naus, M. and Patrick, D.M. and Sbihi, H. and El Adam, S. and Henry, B. and Hoang, L.M.N. and Sadarangani, M. and Jassem, A.N. and Krajden, M.
DOI: 10.1093/cid/ciab616
2022

COVID-19 vaccine uptake and intention during pregnancy in Canada
Canadian Journal of Public Health
Reifferscheid, L. and Marfo, E. and Assi, A. and Dubé, E. and MacDonald, N.E. and Meyer, S.B. and Bettinger, J.A. and Driedger, S.M. and Robinson, J. and Sadarangani, M. and Wilson, S.E. and Benzies, K. and Lemaire-Paquette, S. and Gagneur, A. and MacDonald, S.E.
DOI: 10.17269/s41997-022-00641-9
2022

Child transmission of SARS-CoV-2: a systematic review and meta-analysis
BMC Pediatrics
Silverberg, S.L. and Zhang, B.Y. and Li, S.N.J. and Burgert, C. and Shulha, H.P. and Kitchin, V. and Sauvé, L. and Sadarangani, M.
DOI: 10.1186/s12887-022-03175-8
2022

Does a humoral correlate of protection exist for SARS-CoV-2? A systematic review
PLoS ONE
Perry, J. and Osman, S. and Wright, J. and Richard-Greenblatt, M. and Buchan, S.A. and Sadarangani, M. and Bolotin, S.
DOI: 10.1371/journal.pone.0266852
2022

Physician vaccination practices in mild to moderate inborn errors of immunity and retrospective review of vaccine completeness in IEI: results from the Canadian Immunization Research Network
Allergy, Asthma and Clinical Immunology
Suresh, S. and Zafack, J. and Pham-Huy, A. and Derfalvi, B. and Sadarangani, M. and McConnell, A. and Tapiéro, B. and Halperin, S.A. and De Serres, G. and M Pernica, J. and Top, K.A.
DOI: 10.1186/s13223-022-00667-1
2022

Overview of Vaccine Designs and Performance
World Scientific Series in Global Health Economics and Public Policy
Ackermann, E. and Sadarangani, M.
DOI: 10.1142/9789811249723_0013
2022

Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection: a multicentre cohort study
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
Merckx, J. and Cooke, S. and El Tal, T. and Bitnun, A. and Morris, S.K. and Yeh, E.A. and Yea, C. and Gill, P. and Papenburg, J. and Lefebvre, M.-A. and Scuccimarri, R. and Ulloa-Gutierrez, R. and Brenes-Chacon, H. and Yock-Corrales, A. and Ivankovich-Escoto, G. and Soriano-Fallas, A. and Mezerville, M.H. and Dewan, T. and Restivo, L. and Nateghian, A. and Aski, B.H. and Manafi, A. and Dwilow, R. and Bullard, J. and Lopez, A. and Sadarangani, M. and Roberts, A. and Barton, M. and Petel, D. and Le Saux, N. and Bowes, J. and Purewal, R. and Lautermilch, J. and Tehseen, S. and Bayliss, A. and Wong, J.K. and Leifso, K. and Foo, C. and Robinson, J.
DOI: 10.1503/cmaj.210873
2022

Performance of Immunoglobulin G Serology on Finger Prick Capillary Dried Blood Spot Samples to Detect a SARS-CoV-2 Antibody Response
Microbiology Spectrum
Nikiforuk, A.M. and McMillan, B. and Bartlett, S.R. and Márquez, A.C. and Pidduck, T. and Kustra, J. and Goldfarb, D.M. and Barakauskas, V. and Sinclair, G. and Patrick, D.M. and Sadarangani, M. and Ogilvie, G.S. and Krajden, M. and Morshed, M. and Sekirov, I. and Jassem, A.N.
DOI: 10.1128/spectrum.01405-21
2022

SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada: A cross-sectional study
BMJ Open
Goldfarb, D.M. and Mâsse, L.C. and Watts, A.W. and Hutchison, S.M. and Muttucomaroe, L. and Bosman, E.S. and Barakauskas, V.E. and Choi, A. and Dhillon, N. and Irvine, M.A. and Reicherz, F. and O'Reilly, C. and Sediqi, S. and Xu, R.Y. and Razzaghian, H.R. and Sadarangani, M. and Coombs, D. and O'Brien, S.F. and Lavoie, P.M.
DOI: 10.1136/bmjopen-2021-057846
2022

Immunization in pregnancy to protect pregnant people and their newborns against COVID-19
Expert Review of Vaccines
Delara, M. and Sadarangani, M.
DOI: 10.1080/14760584.2022.2031987
2022

Vaccine effectiveness of the 7-valent and 13-valent pneumococcal conjugate vaccines in Canada: An IMPACT study
Vaccine
Ricketson, L.J. and Bettinger, J.A. and Sadarangani, M. and Halperin, S.A. and Kellner, J.D.
DOI: 10.1016/j.vaccine.2022.03.048
2022

COVID-19 pandemic impact on childhood vaccination coverage in Quebec, Canada
Human Vaccines and Immunotherapeutics
Kiely, M. and Mansour, T. and Brousseau, N. and Rafferty, E. and Paudel, Y.R. and Sadarangani, M. and Svenson, L.W. and Robinson, J.L. and Gagneur, A. and Driedger, S.M. and MacDonald, S.E.
DOI: 10.1080/21645515.2021.2007707
2022

Seroprevalence of IgG and IgM antibodies to Haemophilus influenzae type a in Canadian children
Vaccine
Huska, B. and Kubinec, C. and Sadarangani, M. and Ulanova, M.
DOI: 10.1016/j.vaccine.2022.01.029
2022

Is ‘conflict of interest’ a Misnomer? Managing interests in immunization research and evaluation
Human Vaccines and Immunotherapeutics
McClymont, E. and Brophy, J. and Dubey, V. and Kwong, J. and Meyer, S. and Crowcroft, N. and Halperin, S. and MacDonald, S. and Simmons, K. and Top, K. and Ward, B. and Sadarangani, M.
DOI: 10.1080/21645515.2021.1879580
2022

Infants hospitalized for acute COVID-19: disease severity in a multicenter cohort study
European Journal of Pediatrics
Merckx, J. and Morris, S.K. and Bitnun, A. and Gill, P. and El Tal, T. and Laxer, R.M. and Yeh, A. and Yea, C. and Ulloa-Gutierrez, R. and Brenes-Chacon, H. and Yock-Corrales, A. and Ivankovich-Escoto, G. and Soriano-Fallas, A. and Hernandez-de Mezerville, M. and Papenburg, J. and Lefebvre, M.-A. and Nateghian, A. and Haghighi Aski, B. and Manafi, A. and Dwilow, R. and Bullard, J. and Cooke, S. and Dewan, T. and Restivo, L. and Lopez, A. and Sadarangani, M. and Roberts, A. and Barton, M. and Petel, D. and Le Saux, N. and Bowes, J. and Purewal, R. and Lautermilch, J. and Tehseen, S. and Bayliss, A. and Wong, J.K. and Viel-Thériault, I. and Piche, D. and Top, K.A. and Leifso, K. and Foo, C. and Panetta, L. and Robinson, J.
DOI: 10.1007/s00431-022-04422-x
2022

Intention to Receive a COVID-19 Vaccine by HIV Status Among a Population-Based Sample of Women and Gender Diverse Individuals in British Columbia, Canada
AIDS and Behavior
Kaida, A. and Brotto, L.A. and Murray, M.C.M. and Côté, H.C.F. and Albert, A.Y. and Nicholson, V. and Gormley, R. and Gordon, S. and Booth, A. and Smith, L.W. and Baaske, A. and Galea, L.A.M. and Sadarangani, M. and Ogilvie, G.S.
DOI: 10.1007/s10461-022-03577-w
2022

The effect of the COVID-19 pandemic on influenza-related hospitalization, intensive care admission and mortality in children in Canada: A population-based study
The Lancet Regional Health - Americas
Groves, H.E. and Papenburg, J. and Mehta, K. and Bettinger, J.A. and Sadarangani, M. and Halperin, S.A. and Morris, S.K. and Bancej, C. and Burton, C. and Embree, J. and Foo, C. and Bridger, N. and Morris, R. and Jadavji, T. and Lebel, M. and Le Saux, N. and Top, K.A. and Tan, B. and McConnell, A. and Purewal, R. and Déry, P. and Thibeault, R. and Vaudry, W. and Tran, D. and Sauvé, L. and Moore, D.L. and Lefebvre, M.-A.
DOI: 10.1016/j.lana.2021.100132
2022

The Canadian National Vaccine Safety Network: Surveillance of adverse events following immunisation among individuals immunised with the COVID-19 vaccine, a cohort study in Canada
BMJ Open
Bettinger, J.A. and Sadarangani, M. and De Serres, G. and Valiquette, L. and Vanderkooi, O.G. and Kellner, J.D. and Muller, M.P. and Top, K.A. and Isenor, J.E. and McGeer, A. and Marty, K.
DOI: 10.1136/bmjopen-2021-051254
2022

Clinical Presentations and Outcomes of Children in Canada with Recurrent Invasive Pneumococcal Disease from the IMPACT Surveillance Network
Pediatric Infectious Disease Journal
Murad, Y. and Hung, T.-Y. and Sadarangani, M. and Morris, S.K. and Le Saux, N. and Vanderkooi, O.G. and Kellner, J.D. and Tyrrell, G.J. and Martin, I. and Demczuk, W. and Halperin, S.A. and Bettinger, J.A. and Bridger, N. and Foo, C. and Halperin, S.A. and Top, K.A. and Thibeault, R. and Moore, D. and Papenburg, J. and Lebel, M. and Le Saux, N. and Morris, S. and Embree, J. and Tan, B. and McConnell, A. and Jadavji, T. and Constantinescu, C. and Vaudry, W. and Scheifele, D. and Sadarangani, M. and Bettinger, J. and Sauvé, L.
DOI: 10.1097/INF.0000000000003454
2022

Canadian parents’ perceptions of COVID-19 vaccination and intention to vaccinate their children: Results from a cross-sectional national survey
Vaccine
Robin M. Humble and Hannah Sell and Eve Dubé and Noni E. MacDonald and Joan Robinson and S. Michelle Driedger and Manish Sadarangani and Samantha B. Meyer and Sarah Wilson and Karen M. Benzies and Samuel Lemaire-Paquette and Shannon E. MacDonald
DOI: 10.1016/j.vaccine.2021.10.002
12/2021

PCR and Culture Analysis of Streptococcus pneumoniae Nasopharyngeal Carriage in Healthy Children
Microorganisms
Leah J. Ricketson and Ravinder Lidder and Robyn Thorington and Irene Martin and Otto G. Vanderkooi and Manish Sadarangani and James D. Kellner
DOI: 10.3390/microorganisms9102116
10/2021

Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
Nature Reviews Immunology
Manish Sadarangani and Arnaud Marchant and Tobias R. Kollmann
DOI: 10.1038/s41577-021-00578-z
08/2021

Importance of COVID-19 vaccine efficacy in older age groups
Vaccine
Manish Sadarangani and Bahaa Abu Raya and Jessica M. Conway and Sarafa A. Iyaniwura and Rebeca Cardim Falcao and Caroline Colijn and Daniel Coombs and Soren Gantt
DOI: 10.1016/j.vaccine.2021.03.020
04/2021

The Fifth International Neonatal and Maternal Immunization Symposium (INMIS 2019): Securing Protection for the Next Generation
mSphere
Manish Sadarangani and Tobias Kollmann and Gordean Bjornson and Paul Heath and Ed Clarke and Arnaud Marchant and Ofer Levy and Elke Leuridan and Rolando Ulloa-Gutierrez and Clare L. Cutland and Beate Kampmann and Surasith Chaithongwongwatthana and Ener Dinleyici and Pierre van Damme and Flor M. Munoz
DOI: 10.1128/mSphere.00862-20
02/2021

The influence of sex, gender, age, and ethnicity on psychosocial factors and substance use throughout phases of the COVID-19 pandemic
PLoS ONE
Brotto, L.A. and Chankasingh, K. and Baaske, A. and Albert, A. and Booth, A. and Kaida, A. and Smith, L.W. and Racey, S. and Gottschlich, A. and Murray, M.C.M. and Sadarangani, M. and Ogilvie, G.S. and Galea, L.
DOI: 10.1371/journal.pone.0259676
2021

Understanding Influenza Vaccination During Pregnancy in Canada: Attitudes, Norms, Intentions, and Vaccine Uptake
Health Education and Behavior
Greyson, D. and Dubé, ?. and Fisher, W.A. and Cook, J. and Sadarangani, M. and Bettinger, J.A.
DOI: 10.1177/10901981211001863
2021

The Fifth International Neonatal and Maternal Immunization Symposium (INMIS 2019): Securing Protection for the Next Generation
mSphere
Sadarangani, M. and Kollmann, T. and Bjornson, G. and Heath, P. and Clarke, E. and Marchant, A. and Levy, O. and Leuridan, E. and Ulloa-Gutierrez, R. and Cutland, C.L. and Kampmann, B. and Chaithongwongwatthana, S. and Dinleyici, E. and Damme, P.V. and Munoz, F.M.
DOI: 10.1128/MSPHERE.00862-20
2021

Declining rates of cervical intraepithelial neoplasia in British Columbia, Canada: An ecological analysis on the effects of the school-based human papillomavirus vaccination program
International Journal of Cancer
Donken, R. and van Niekerk, D. and Hamm, J. and Spinelli, J.J. and Smith, L. and Sadarangani, M. and Albert, A. and Money, D. and Dobson, S. and Miller, D. and Lee, M. and Mitchell-Foster, S. and Krajden, M. and Naus, M. and Ogilvie, G.
DOI: 10.1002/ijc.33513
2021

Health outcomes in young children following pertussis vaccination during pregnancy
Pediatrics
Laverty, M. and Crowcroft, N. and Bolotin, S. and Hawken, S. and Wilson, K. and Amirthalingam, G. and Biringer, A. and Cook, J. and Dubey, V. and Fakhraei, R. and Halperin, S.A. and Jamieson, F. and Kwong, J.C. and Sadarangani, M. and Sucha, E. and Walker, M.C. and Fell, D.B.
DOI: 10.1542/peds.2020-042507
2021

Bacterial meningitis in children: Neurological complications, associated risk factors, and prevention
Microorganisms
Zainel, A. and Mitchell, H. and Sadarangani, M.
DOI: 10.3390/microorganisms9030535
2021

Machine Learning-Based Single Cell and Integrative Analysis Reveals That Baseline mDC Predisposition Correlates With Hepatitis B Vaccine Antibody Response
Frontiers in Immunology
Aevermann, B.D. and Shannon, C.P. and Novotny, M. and Ben-Othman, R. and Cai, B. and Zhang, Y. and Ye, J.C. and Kobor, M.S. and Gladish, N. and Lee, A.H.-Y. and Blimkie, T.M. and Hancock, R.E. and Llibre, A. and Duffy, D. and Koff, W.C. and Sadarangani, M. and Tebbutt, S.J. and Kollmann, T.R. and Scheuermann, R.H.
DOI: 10.3389/fimmu.2021.690470
2021

Factors affecting antibody responses to immunizations in infants born to women immunized against pertussis in pregnancy and unimmunized women: Individual-Participant Data Meta-analysis
Vaccine
Abu-Raya, B. and Maertens, K. and Munoz, F.M. and Zimmermann, P. and Curtis, N. and Halperin, S.A. and Rots, N. and Barug, D. and Holder, B. and Rice, T.F. and Kampmann, B. and Leuridan, E. and Sadarangani, M.
DOI: 10.1016/j.vaccine.2021.09.022
2021

Priorities for sexually transmitted infection vaccine research and development: Results from a survey of global leaders and representatives
Vaccine: X
Plotnikoff, K.M. and Donken, R. and Smith, L. and Cameron, C. and LaMontagne, D.S. and Bettinger, J.A. and Sadarangani, M. and Grennan, T. and Racey, C.S. and Hybiske, K. and Naus, M. and Monteiro, A. and Ogilvie, G.S.
DOI: 10.1016/j.jvacx.2021.100107
2021

Intentions of public school teachers in British Columbia, Canada to receive a COVID-19 vaccine
Vaccine: X
Racey, C.S. and Donken, R. and Porter, I. and Albert, A. and Bettinger, J.A. and Mark, J. and Bonifacio, L. and Dawar, M. and Gagel, M. and Kling, R. and Mema, S. and Mitchell, H. and Roe, I. and Ogilvie, G. and Sadarangani, M.
DOI: 10.1016/j.jvacx.2021.100106
2021

Characteristics of children admitted to hospital with acute sars-cov-2 infection in Canada in 2020
CMAJ
Drouin, O. and Hepburn, C.M. and Farrar, D.S. and Baerg, K. and Chan, K. and Cyr, C. and Donner, E.J. and Embree, J.E. and Farrell, C. and Forgie, S. and Giroux, R. and Kang, K.T. and King, M. and Laffin, M. and Luu, T.M. and Orkin, J. and Papenburg, J. and Pound, C.M. and Price, V.E. and Purewal, R. and Sadarangani, M. and Salvadori, M.I. and Top, K.A. and Viel-Theriault, I. and Kakkar, F. and Morris, S.K.
DOI: 10.1503/cmaj.210053
2021

Neurological Manifestations of SARS-CoV-2 in Hospitalized Children: A Multi-National Cohort Study
SSRN
Yea, C. and Barton, M. and Bitnun, A. and Morris, S.K. and Tal, T.E. and Ulloa-Gutierrez, R. and Brenes-Chacon, H. and Yock-Corrales, A. and Ivankovich-Escoto, G. and Soriano-Fallas, A. and de Mezerville, M.H. and Laxer, R.M. and Gill, P. and Nateghian, A. and Aski, B.H. and Manafi, A.A. and Dwilow, R. and Bullard, J. and Papenburg, J. and Lefebvre, M.-A. and Cooke, S. and Dewan, T. and Restivo, L. and Lopez, A. and Sadarangani, M. and Roberts, A. and Wong, J. and Le Saux, N. and Bowes, J. and Purewal, R. and Lautermilch, J. and Foo, C. and Robinson, J. and Yeh, E.A.
DOI: 10.2139/ssrn.3831858
2021

The Effect of Tetanus-Diphtheria-Acellular-Pertussis Immunization During Pregnancy on Infant Antibody Responses: Individual-Participant Data Meta-Analysis
Frontiers in Immunology
Abu-Raya, B. and Maertens, K. and Munoz, F.M. and Zimmermann, P. and Curtis, N. and Halperin, S.A. and Rots, N. and Barug, D. and Holder, B. and Kampmann, B. and Leuridan, E. and Sadarangani, M.
DOI: 10.3389/fimmu.2021.689394
2021

Intention to receive a COVID-19 vaccine: results from a population-based survey in Canada
BMC Public Health
Ogilvie, G.S. and Gordon, S. and Smith, L.W. and Albert, A. and Racey, C.S. and Booth, A. and Gottschlich, A. and Goldfarb, D. and Murray, M.C.M. and Galea, L.A.M. and Kaida, A. and Brotto, L.A. and Sadarangani, M.
DOI: 10.1186/s12889-021-11098-9
2021

Obstetric and perinatal health outcomes after pertussis vaccination during pregnancy in Ontario, Canada: a retrospective cohort study
CMAJ open
Fakhraei, R. and Crowcroft, N. and Bolotin, S. and Sucha, E. and Hawken, S. and Wilson, K. and Gaudet, L. and Amirthalingam, G. and Biringer, A. and Cook, J. and Dubey, V. and Halperin, S.A. and Jamieson, F. and Kwong, J.C. and Sadarangani, M. and Walker, M.C. and Laverty, M. and Fell, D.B.
DOI: 10.9778/cmajo.20200239
2021

14-year trends and resistance patterns of blood and cerebrospinal fluid cultures in children under three years old
Journal of Infection
Takata, J. and Kelly, D.F. and Sadarangani, M. and Jeffery, K. and Drysdale, S.B.
DOI: 10.1016/j.jinf.2021.08.048
2021

Non-inferior antibody levels for HPV16/18 after extended two-dose schedules compared with a six-month interval: findings of a systematic review and meta-analysis
Human vaccines & immunotherapeutics
Collins-Fairclough, A. and Donken, R. and Nosyk, B. and Dobson, S. and Ogilivie, G. and Sadarangani, M.
DOI: 10.1080/21645515.2021.1926182
2021

Characteristics of children admitted to hospital with acute SARS-CoV-2 infection in Canada in 2020,Caractéristiques des hospitalisations au Canada d'enfants ayant contracté une infection aiguë par le SRAS-CoV-2 en 2020
CMAJ
Drouin, O. and Hepburn, C.M. and Farrar, D.S. and Baerg, K. and Chan, K. and Cyr, C. and Donner, E.J. and Embree, J.E. and Farrell, C. and Forgie, S. and Giroux, R. and Kang, K.T. and King, M. and Laffin, M. and Luu, T.M. and Orkin, J. and Papenburg, J. and Pound, C.M. and Price, V.E. and Purewal, R. and Sadarangani, M. and Salvadori, M.I. and Top, K.A. and Viel-Thériault, I. and Kakkar, F. and Morris, S.K.
DOI: 10.1503/CMAJ.210053-F
2021

Population-based incidence of invasive pneumococcal disease in children and adults in Ontario and British Columbia, 2002–2018: A Canadian Immunization Research Network (CIRN) study
Vaccine
Nasreen, S. and Wang, J. and Kwong, J.C. and Crowcroft, N.S. and Sadarangani, M. and Wilson, S.E. and McGeer, A. and Kellner, J.D. and Quach, C. and Morris, S.K. and Sander, B. and Kus, J.V. and Naus, M. and Hoang, L. and Rudzicz, F. and Fadel, S. and Marra, F.
DOI: 10.1016/j.vaccine.2021.11.032
2021

Continuity of routine immunization programs in Canada during the COVID-19 pandemic
Vaccine
Sell, H. and Assi, A. and Driedger, S.M. and Dubé, ?. and Gagneur, A. and Meyer, S.B. and Robinson, J. and Sadarangani, M. and Tunis, M. and MacDonald, S.E.
DOI: 10.1016/j.vaccine.2021.08.044
2021

Antiviral use in Canadian children hospitalized for influenza
Pediatrics
Mehta, K. and Morris, S.K. and Bettinger, J.A. and Vaudry, W. and Jadavji, T. and Halperin, S.A. and Bancej, C. and Sadarangani, M. and Dendukuri, N. and Papenburg, J.
DOI: 10.1542/peds.2020-049672
2021

Association between human papillomavirus vaccine status and sexually transmitted infection outcomes among females aged 18-35 with a history of sexual activity in the United States: A population survey-based cross-sectional analysis
Vaccine
Kalysha Closson and Mohammad E. Karim and Manish Sadarangani and Monika Naus and Gina S. Ogilvie and Robine Donken
DOI: 10.1016/j.vaccine.2020.10.033
12/2020

Environmental scan of provincial and territorial planning for COVID-19 vaccination programs
MacDonald SE and Sell H and Wilson S and Meyer SB and Gagneur A and Assi A and Sadarangani M and And members of the COVImm study team
DOI: 10.1101/2020.12.22.20248685
12/2020

Epidemiology of Burkholderia Infections in People with Cystic Fibrosis in Canada between 2000 and 2017.
Annals of the American Thoracic Society
Zlosnik JEA and Henry DA and Hird TJ and Hickman R and Campbell M and Cabrera A and Laino Chiavegatti G and Chilvers MA and Sadarangani M
DOI: 10.1513/annalsats.201906-443oc
PubMed: 32946281
12/2020

Canadian surveillance of COVID-19 in pregnancy: Epidemiology and maternal and infant outcomes
American journal of obstetrics and gynecology
McClymont E and Fell D and Albert A and Alton G and Barrett J and El-Chaar D and Harrold J and Krajden M and Lipsky N and Maan E and Malinowski A and Othman M and Raeside A and Ray J and Money D
11/2020

Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults.
Frontiers in immunology
Ben-Othman R and Cai B and Liu AC and Varankovich N and He D and Blimkie TM and Lee AH and Gill EE and Novotny M and Aevermann B and Drissler S and Shannon CP and McCann S and Marty K and Sadarangani M
DOI: 10.3389/fimmu.2020.580373
PubMed: 33250895
11/2020

Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small Cohort.
Frontiers in immunology
Shannon CP and Blimkie TM and Ben-Othman R and Gladish N and Amenyogbe N and Drissler S and Edgar RD and Chan Q and Krajden M and Foster LJ and Kobor MS and Mohn WW and Brinkman RR and Lee AH
DOI: 10.3389/fimmu.2020.578801
PubMed: 33329547
11/2020

Gene expression profiling reveals insights into infant immunological and febrile responses to group B meningococcal vaccine.
Molecular systems biology
O'Connor D and Pinto MV and Sheerin D and Tomic A and Drury RE and Channon-Wells S and Galal U and Dold C and Robinson H and Kerridge S and Plested E and Hughes H and Stockdale L and Pollard AJ
DOI: 10.15252/msb.20209888
PubMed: 33210468
11/2020

Maternal Immunological Adaptation During Normal Pregnancy
Frontiers in Immunology
Bahaa Abu-Raya and Christina Michalski and Manish Sadarangani and Pascal M. Lavoie
DOI: 10.3389/fimmu.2020.575197
10/2020

Pertussis vaccination in pregnancy in Canada: a cost-utility analysis.
CMAJ open
Abu-Raya B and Coyle D and Bettinger JA and Vaudry W and Halperin SA and Sadarangani M and for members of the Canadian Immunization Monitoring Program and ACTive (IMPACT)
DOI: 10.9778/cmajo.20200060
PubMed: 33077536
10/2020

Incidence of invasive pneumococcal disease after introduction of the 13-valent conjugate pneumococcal vaccine in British Columbia: A retrospective cohort study
PLOS ONE
Nirma Khatri Vadlamudi and David M. Patrick and Linda Hoang and Manish Sadarangani and Fawziah Marra
DOI: 10.1371/journal.pone.0239848
09/2020

Matrix-assisted laser desorption/ionization time-of-flight MS for the accurate identification of Burkholderia cepacia complex and Burkholderia gladioli in the clinical microbiology laboratory
Journal of Medical Microbiology
Kendrew S. K. Wong and Suk Dhaliwal and Jennifer Bilawka and Jocelyn A. Srigley and Sylvie Champagne and Marc G. Romney and Peter Tilley and Manish Sadarangani and James E. A. Zlosnik and Mark A. Chilvers
DOI: 10.1099/jmm.0.001223
08/2020

Immunogenicity of 2 and 3 Doses of the Quadrivalent Human Papillomavirus Vaccine up to 120 Months Postvaccination: Follow-up of a Randomized Clinical Trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Donken R and Dobson SRM and Marty KD and Cook D and Sauvageau C and Gilca V and Dionne M and McNeil S and Krajden M and Money D and Kellner J and Scheifele DW and Kollmann T and Ogilvie GS
DOI: 10.1093/cid/ciz887
PubMed: 31617568
08/2020

Profiling avidity of antibodies elicited by vaccination using enzyme-linked immunosorbent assay-based elution – Insights into a novel experimental and analytical approach
Vaccine
Bahaa Abu-Raya and Michelle L Giles and Tobias R. Kollmann and Manish Sadarangani
DOI: 10.1016/j.vaccine.2020.06.060
07/2020

Challenges in evaluating SARS-CoV-2 vaccines during the COVID-19 pandemic.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
Abu-Raya B and Gantt S and Sadarangani M
DOI: 10.1503/cmaj.201237
PubMed: 32646869
07/2020

Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 From the Mother to the Infant.
JAMA pediatrics
Abu Raya B and Giles ML and Sadarangani M
DOI: 10.1001/jamapediatrics.2020.2150
PubMed: 32687555
07/2020

What is the role of SARS-CoV-2 PCR testing in discontinuation of transmission-based precautions for COVID-19 patients?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Abu Raya B and Goldfarb DM and Sadarangani M
DOI: 10.1093/cid/ciaa671
PubMed: 32472672
05/2020

Study protocol: NeoCLEAR: Neonatal Champagne Lumbar punctures Every time - An RCT: a multicentre, randomised controlled 2¿×¿2 factorial trial to investigate techniques to increase lumbar puncture success.
BMC pediatrics
Marshall ASJ and Sadarangani M and Scrivens A and Williams R and Yong J and Bowler U and Linsell L and Chiocchia V and Bell JL and Stokes C and Santhanadass P and Adams E and ‘The NeoCLEAR Collaborative Group’
DOI: 10.1186/s12887-020-02050-8
PubMed: 32295554
04/2020

Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
Trends in immunology
Tsang JS and Dobaño C and VanDamme P and Moncunill G and Marchant A and Othman RB and Sadarangani M and Koff WC and Kollmann TR
DOI: 10.1016/j.it.2020.04.001
PubMed: 32340868
04/2020

Neuropsychological and psychiatric outcomes in encephalitis: A multi-centre case-control study.
PloS one
Harris L and Griem J and Gummery A and Marsh L and Defres S and Bhojak M and Das K and Easton A and Solomon T and Kopelman M and ENCEPH UK study group
DOI: 10.1371/journal.pone.0230436
PubMed: 32210460
03/2020

Estimated susceptibility of Canadian meningococcal B isolates to a meningococcal serogroup B vaccine (MenB-FHbp)
Vaccine
Julie A. Bettinger and Paul Liberator and Scott A. Halperin and Wendy Vaudry and Manish Sadarangani and Li Hao and Nathaniel Lambert and Kathrin U. Jansen and Annaliesa S. Anderson and Raymond Tsang
DOI: 10.1016/j.vaccine.2019.12.051
02/2020

Cervical Intraepithelial Neoplasia Rates in British Columbia Women: A Population-Level Data Linkage Evaluation of the School-Based HPV Immunization Program.
The Journal of infectious diseases
Racey CS and Albert A and Donken R and Smith L and Spinelli JJ and Pedersen H and de Bruin P and Masaro C and Mitchell-Foster S and Sadarangani M and Dawar M and Krajden M and Naus M and Ogilvie G
DOI: 10.1093/infdis/jiz422
PubMed: 31504649
01/2020

Pharmacological Treatment for Patients with Coronavirus Disease 2019: Systematic Review of Randomized Controlled Trials
SSRN
Abu-Raya, B. and Mijovic, H. and Donken, R. and Cabrera, A. and Kitchin, V. and Chow, R. and Leishman, R. and Pan, C. and Paquette, V. and Roberts, A. and Sadarangani, M.
DOI: 10.2139/ssrn.3696883
2020

Challenges in evaluating SARS-CoV-2 vaccines during the COVID-19 pandemic,Difficultés associées à l’évaluation des vaccins contre le SRAS-CoV-2 pendant la pandémie de COVID-19
CMAJ
Abu-Raya, B. and Gantt, S. and Sadarangani, M.
DOI: 10.1503/CMAJ.201237-F
2020

Epidemiology of burkholderia infections in people with cystic fibrosis in Canada between 2000 and 2017
Annals of the American Thoracic Society
Zlosnik, J.E.A. and Henry, D.A. and Hird, T.J. and Hickman, R. and Campbell, M. and Cabrera, A. and Chiavegatti, G.L. and Chilvers, M.A. and Sadarangani, M.
DOI: 10.1513/AnnalsATS.201906-443OC
2020

Outcomes beyond hospital discharge in infants and children with viral meningitis: A systematic review
Reviews in Medical Virology
Hudson, J.A. and Broad, J. and Martin, N.G. and Sadarangani, M. and Galal, U. and Kelly, D.F. and Pollard, A.J. and Kadambari, S.
DOI: 10.1002/rmv.2083
2020

Burden of children hospitalized with pertussis in Canada in the acellular pertussis vaccine era, 1999-2015
Journal of the Pediatric Infectious Diseases Society
Abu-Raya, B. and Bettinger, J.A. and Vanderkooi, O.G. and Vaudry, W. and Halperin, S.A. and Sadarangani, M.
DOI: 10.1093/JPIDS/PIY128
2020

Is there a difference in the immune response, efficacy, effectiveness and safety of seasonal influenza vaccine in males and females? – A systematic review
Vaccine
Tadount, F. and Doyon-Plourde, P. and Rafferty, E. and MacDonald, S. and Sadarangani, M. and Quach, C.
DOI: 10.1016/j.vaccine.2019.10.091
2020

Fifteen-minute consultation: Prevention and treatment of chickenpox in newborns
Archives of Disease in Childhood: Education and Practice Edition
Holland, C. and Sadarangani, M.
DOI: 10.1136/archdischild-2018-316715
2020

The prevalence and clinical characteristics of pertussis-associated pneumonia among infants in Botswana.
BMC pediatrics
Abu-Raya B and Goldfarb DM and Smieja M and Luinstra K and Richard-Greenblatt M and Steenhoff AP and Feemster KA and Arscott-Mills T and Cunningham CK and Shah SS and Patel MZ and Sadarangani M
DOI: 10.1186/s12887-019-1820-0
PubMed: 31733643
11/2019

The Effect of Timing of Tetanus-Diphtheria-Acellular Pertussis Vaccine Administration in Pregnancy on the Avidity of Pertussis Antibodies.
Frontiers in immunology
Abu-Raya B and Giles ML and Kollmann TR and Sadarangani M
DOI: 10.3389/fimmu.2019.02423
PubMed: 31681310
10/2019

Comparative transcriptomics between species attributes reactogenicity pathways induced by the capsular group B meningococcal vaccine, 4CMenB, to the membrane-bound endotoxin of its outer membrane vesicle component.
Scientific reports
Sheerin D and O'Connor D and Dold C and Clutterbuck E and Attar M and Rollier CS and Sadarangani M and Pollard AJ
DOI: 10.1038/s41598-019-50310-0
PubMed: 31551511
09/2019

Understanding parental perspectives on outcomes following paediatric encephalitis: A qualitative study.
PloS one
Lemon J and Cooper J and Defres S and Easton A and Sadarangani M and Griffiths MJ and Pollard AJ and Solomon T and Kneen R
DOI: 10.1371/journal.pone.0220042
PubMed: 31525232
09/2019

Recurrent immune thrombocytopenia following different vaccines.
BMJ case reports
Morin E and Sadarangani M
DOI: 10.1136/bcr-2019-231260
PubMed: 31540926
09/2019

Meningitis vaccines in children: what have we achieved and where next?
Current opinion in infectious diseases
McAlpine A and Sadarangani M
DOI: 10.1097/qco.0000000000000580
PubMed: 31335439
07/2019

A Population-based Observational Study of Childhood Encephalitis in Children Admitted to Pediatric Intensive Care Units in England and Wales.
The Pediatric infectious disease journal
Iro MA and Sadarangani M and Nickless A and Kelly DF and Pollard AJ
DOI: 10.1097/inf.0000000000002280
PubMed: 30640197
07/2019

Targeted metagenomic sequencing enhances the identification of pathogens associated with acute infection
Goh C and Golubchik T and Ansari MA and de Cesare M and Trebes A and Elliott I and Bonsall D and Piazza P and Brown A and Slawinski H and Martin N and Defres S and Griffiths MJ and Bowden R
DOI: 10.1101/716902
07/2019

Dilemmas With Rotavirus Vaccine: The Neonate and Immunocompromised.
The Pediatric infectious disease journal
Chiu M and Bao C and Sadarangani M
DOI: 10.1097/inf.0000000000002322
PubMed: 31205244
06/2019

To LP or not to LP? Identifying the Etiology of Pediatric Meningitis.
The Pediatric infectious disease journal
Mijovic H and Sadarangani M
DOI: 10.1097/inf.0000000000002313
PubMed: 31205243
06/2019

42 A risk factor approach is highly effective at selecting 29-34w gestation infants at risk for first season RSV-related admissions – a population study.
Paediatrics & Child Health
Sidi S and Claydon J and Solimano A and Taylor R and Lavoie P and Christopherson C and Kuzeljevic B and Gantt S and Sadarangani M and Burns G and Bayzand L
05/2019

41 Lessons learned during the practice of a no-conflict of-interest panel-of-three adjudication process in the RSV program.
Paediatrics & Child Health
Sidi S and Claydon J and Christopherson C and Taylor R and Gantt S and Sadarangani M and Lavoie P and Solimano A
05/2019

From mother to baby: antenatal exposure to monoclonal antibody biologics.
Expert review of clinical immunology
Pham-Huy A and Sadarangani M and Huang V and Ostensen M and Castillo E and Troster SM and Vaudry W and Nguyen GC and Top KA
DOI: 10.1080/1744666x.2019.1561282
PubMed: 30570400
01/2019

To LP or not to LP? Identifying the Etiology of Pediatric Meningitis
Pediatric Infectious Disease Journal
Mijovic, H. and Sadarangani, M. and Sadarangani, M.
DOI: 10.1097/INF.0000000000002313
2019

Separating myths from reality for vaccines causing adverse events following immunization: An interview with Manish Sadarangani
Future Microbiology
Sadarangani, M.
DOI: 10.2217/fmb-2019-0187
2019

Meningitis vaccines in children: What have we achieved and where next?
Current Opinion in Infectious Diseases
McAlpine, A. and Sadarangani, M.
DOI: 10.1097/QCO.0000000000000580
2019

Strategies to improve detection and management of human parechovirus infection in young infants
The Lancet Infectious Diseases
Kadambari, S. and Harvala, H. and Simmonds, P. and Pollard, A.J. and Sadarangani, M.
DOI: 10.1016/S1473-3099(18)30288-3
2019

A Population-based Observational Study of Childhood Encephalitis in Children Admitted to Pediatric Intensive Care Units in England and Wales
The Pediatric infectious disease journal
Iro, M.A. and Sadarangani, M. and Nickless, A. and Kelly, D.F. and Pollard, A.J.
DOI: 10.1097/INF.0000000000002280
2019

Dilemmas With Rotavirus Vaccine: The Neonate and Immunocompromised
The Pediatric infectious disease journal
Chiu, M. and Bao, C. and Sadarangani, M.
DOI: 10.1097/INF.0000000000002322
2019

From mother to baby: antenatal exposure to monoclonal antibody biologics
Expert Review of Clinical Immunology
Pham-Huy, A. and Sadarangani, M. and Huang, V. and Ostensen, M. and Castillo, E. and Troster, S.M. and Vaudry, W. and Nguyen, G.C. and Top, K.A.
DOI: 10.1080/1744666X.2019.1561282
2019

Burden of Children Hospitalized With Pertussis in Canada in the Acellular Pertussis Vaccine Era, 1999-2015.
Journal of the Pediatric Infectious Diseases Society
Abu-Raya B and Bettinger JA and Vanderkooi OG and Vaudry W and Halperin SA and Sadarangani M and Members of the Canadian Immunization Monitoring Program and Active (IMPACT)
DOI: 10.1093/jpids/piy128
PubMed: 30535079
12/2018

2466. Evaluation of Immunization on the Neonatal Intensive Care Unit at British Columbia Women’s Hospital.
Open forum infectious diseases
Chiu M and Bao C and Vahedi Y and Paquette V and Osiovich H and Sadarangani M
DOI: 10.1093/ofid/ofy210.2119
11/2018

Protection Against Invasive Infections in Children Caused by Encapsulated Bacteria.
Frontiers in immunology
Sadarangani M
DOI: 10.3389/fimmu.2018.02674
PubMed: 30515161
11/2018

153. The Effect of Timing of Tetanus–Diphtheria and Pertussis Vaccine Administration in Pregnancy on The Avidity of Pertussis Antibodies.
Open forum infectious diseases
Raya BA and Giles M and Kollmann T and Sadarangani M
DOI: 10.1093/ofid/ofy209.023
11/2018

Strategies to improve detection and management of human parechovirus infection in young infants.
The Lancet. Infectious diseases
Kadambari S and Harvala H and Simmonds P and Pollard AJ and Sadarangani M
DOI: 10.1016/s1473-3099(18)30288-3
PubMed: 30322791
10/2018

Computing threshold antibody levels of protection in vaccine clinical trials: An assessment of methodological bias.
PloS one
Voysey M and Sadarangani M and Pollard AJ and Fanshawe TR
DOI: 10.1371/journal.pone.0202517
PubMed: 30192787
09/2018

Effect of human papillomavirus vaccination on sexual behaviour among young females.
Canadian family physician Medecin de famille canadien
Donken R and Ogilvie GS and Bettinger JA and Sadarangani M and Goldman RD
PubMed: 30002026
07/2018

Immunization in Pregnancy: The Future for Neonatal Protection.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Castillo E and Sadarangani M
DOI: 10.1016/j.jogc.2018.02.006
PubMed: 29680069
04/2018

L'immunisation pendant la grossesse : l'avenir de la protection néonatale.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
DOI: 10.1016/j.jogc.2018.02.015
PubMed: 29680070
04/2018

Meningococcal vaccination in pregnancy.
Human vaccines & immunotherapeutics
Abu Raya B and Sadarangani M
DOI: 10.1080/21645515.2018.1445447
PubMed: 29485347
03/2018

Management of suspected paediatric meningitis: a multicentre prospective cohort study.
Archives of disease in childhood
Ramasamy R and Willis L and Kadambari S and Kelly DF and Heath PT and Nadel S and Pollard AJ and Sadarangani M
DOI: 10.1136/archdischild-2017-313913
PubMed: 29436406
02/2018

Effect of human papillomavirus vaccination on sexual behaviour among young females
Canadian Family Physician
Donken, R. and Ogilvie, G.S. and Bettinger, J.A. and Sadarangani, M. and Goldman, R.D.
2018

Persistence of immunity after vaccination with a capsular group B meningococcal vaccine in 3 different toddler schedules
Canadian Medical Association Journal
Manish Sadarangani and Tim Sell and Mildred A. Iro and Matthew D. Snape and Merryn Voysey and Adam Finn and Paul T. Heath and Gianni Bona and Susanna Esposito and Javier Diez-Domingo and Roman Prymula and Adefowope Odueyungbo and Daniela Toneatto and Andrew J. Pollard
DOI: 10.1503/cmaj.161288
10/2017

Prevalence and decay of maternal pneumococcal and meningococcal antibodies: A meta-analysis of type-specific decay rates
Vaccine
Merryn Voysey and Andrew J. Pollard and Manish Sadarangani and Thomas R. Fanshawe
DOI: 10.1016/j.vaccine.2017.09.002
10/2017

Care beyond the hospital ward: understanding the socio-medical trajectory of herpes simplex virus encephalitis.
BMC health services research
Cooper J and Kierans C and Defres S and Easton A and Kneen R and Solomon T and ENCEPH-UK study group
DOI: 10.1186/s12913-017-2608-2
PubMed: 28899392
09/2017

Maternal immunisation: collaborating with mother nature
The Lancet Infectious Diseases
Arnaud Marchant and Manish Sadarangani and Mathieu Garand and Nicolas Dauby and Valerie Verhasselt and Lenore Pereira and Gordean Bjornson and Christine E Jones and Scott A Halperin and Kathryn M Edwards and Paul Heath and Peter J Openshaw and David W Scheifele and Tobias R Kollmann
DOI: 10.1016/s1473-3099(17)30229-3
07/2017

Group B streptococcus and respiratory syncytial virus immunisation during pregnancy: a landscape analysis
The Lancet Infectious Diseases
Paul T Heath and Fiona J Culley and Christine E Jones and Beate Kampmann and Kirsty Le Doare and Marta C Nunes and Manish Sadarangani and Zain Chaudhry and Carol J Baker and Peter J M Openshaw
DOI: 10.1016/s1473-3099(17)30232-3
07/2017

The Influence of Maternally Derived Antibody and Infant Age at Vaccination on Infant Vaccine Responses
JAMA Pediatrics
Merryn Voysey and Dominic F. Kelly and Thomas R. Fanshawe and Manish Sadarangani and Katherine L. O’Brien and Rafael Perera and Andrew J. Pollard
DOI: 10.1001/jamapediatrics.2017.0638
07/2017

Whither vaccines?
Journal of Infection
Charlene M.C. Rodrigues and Marta V. Pinto and Manish Sadarangani and Stanley A. Plotkin
DOI: 10.1016/s0163-4453(17)30184-6
06/2017

30-year trends in admission rates for encephalitis in children in England and effect of improved diagnostics and measles-mumps-rubella vaccination: a population-based observational study
The Lancet Infectious Diseases
Mildred A Iro and Manish Sadarangani and Raphael Goldacre and Alecia Nickless and Andrew J Pollard and Michael J Goldacre
DOI: 10.1016/s1473-3099(17)30114-7
04/2017

Four Component Meningococcal Capsular Group B Vaccine in Preterm Infants
Journal of the Pediatric Infectious Diseases Society
Manish Sadarangani and Sheula Barlow and Mark Anthony and Andrew J Pollard
DOI: 10.1093/jpids/pix013
03/2017

Age-specific trends in antibiotic resistance in Escherichia coli infections in Oxford, United Kingdom 2013–2014
Journal of Infection
Rebecca C. Robey and Simon B. Drysdale and Dominic F. Kelly and Ian CJW. Bowler and Manish Sadarangani
DOI: 10.1016/j.jinf.2016.10.006
02/2017

A Feasibility Study of Quantifying Longitudinal Brain Changes in Herpes Simplex Virus (HSV) Encephalitis Using Magnetic Resonance Imaging (MRI) and Stereology.
PloS one
DOI: 10.1371/journal.pone.0170215
PubMed: 28125598
01/2017

Immunizing Patients with Adverse Events Following Immunization in the Canadian Special Immunization Clinic Network (2015–2017)
Open Forum Infectious Diseases
Karina A Top and Francois D Boucher and Athena McConnell and Jeffrey Pernica and Anne Pham-Huy and Wendy Vaudry and Shelley L Deeks and Francisco Noya and Bruce Tapiero and Caroline Quach and Dat Tran and Shaun K Morris and Simon Dobson and Manish Sadarangani and Shelly A McNeil and Donna MacKinnon-Cameron and Lingyun Ye and Scott A Halperin and Gaston De Serres
DOI: 10.1093/ofid/ofx163.1339
2017

30-year trends in admission rates for encephalitis in children in England and effect of improved diagnostics and measles-mumps-rubella vaccination: a population-based observational study
The Lancet Infectious Diseases
Iro, M.A. and Sadarangani, M. and Goldacre, R. and Nickless, A. and Pollard, A.J. and Goldacre, M.J.
DOI: 10.1016/S1473-3099(17)30114-7
2017

Pneumocystis jirovecii pneumonia in pediatric inflammatory bowel disease: A case report and literature review
Frontiers in Pediatrics
Lawrence, S.J. and Sadarangani, M. and Jacobson, K.
DOI: 10.3389/fped.2017.00161
2017

Maternal immunisation: collaborating with mother nature
The Lancet Infectious Diseases
Marchant, A. and Sadarangani, M. and Garand, M. and Dauby, N. and Verhasselt, V. and Pereira, L. and Bjornson, G. and Jones, C.E. and Halperin, S.A. and Edwards, K.M. and Heath, P. and Openshaw, P.J. and Scheifele, D.W. and Kollmann, T.R.
DOI: 10.1016/S1473-3099(17)30229-3
2017

Whither vaccines?
Journal of Infection
Rodrigues, C.M.C. and Pinto, M.V. and Sadarangani, M. and Plotkin, S.A.
DOI: 10.1016/S0163-4453(17)30184-6
2017

Group B streptococcus and respiratory syncytial virus immunisation during pregnancy: a landscape analysis
The Lancet Infectious Diseases
Heath, P.T. and Culley, F.J. and Jones, C.E. and Kampmann, B. and Le Doare, K. and Nunes, M.C. and Sadarangani, M. and Chaudhry, Z. and Baker, C.J. and Openshaw, P.J.M.
DOI: 10.1016/S1473-3099(17)30232-3
2017

Meningococcal Vaccines
Pediatric Vaccines and Vaccinations
DOI: 10.1007/978-3-319-59952-6_22
2017

Hospital admissions for viral meningitis in children in England over five decades: a population-based observational study
The Lancet Infectious Diseases
Natalie G Martin and Mildred A Iro and Manish Sadarangani and Raphael Goldacre and Andrew J Pollard and Michael J Goldacre
DOI: 10.1016/s1473-3099(16)30201-8
11/2016

Symptomatic stroke complicating central skull base osteomyelitis following otitis media in a 2-year old boy: Case report and review of the literature
International Journal of Pediatric Otorhinolaryngology
Eliz Kilich and Reena Dwivedi and Shelley Segal and Sandeep Jayawant and Manish Sadarangani
DOI: 10.1016/j.ijporl.2016.08.003
10/2016

Gene expression profiles are different in venous and capillary blood: Implications for vaccine studies
Vaccine
D.F. Stein and D. O’Connor and C.J. Blohmke and M. Sadarangani and A.J. Pollard
DOI: 10.1016/j.vaccine.2016.09.007
10/2016

Strengthening the Reporting of Observational Studies in Epidemiology for Newborn Infection (STROBE-NI): an extension of the STROBE statement for neonatal infection research.
The Lancet. Infectious Diseases
Fitchett EJA and Seale AC and Vergnano S and Sharland M and Heath PT and Saha SK and Agarwal R and Ayede AI and Bhutta ZA and Black R and Bojang K and Campbell H and Cousens S and SPRING (Strengthening Publications Reporting Infection in Newborns Globally) Group
DOI: 10.1016/s1473-3099(16)30082-2
PubMed: 27633910
09/2016

Use of rotavirus vaccines in preterm babies on the neonatal unit
Expert Review of Vaccines
Eliz Kilich and Manish Sadarangani
DOI: 10.1080/14760584.2016.1216318
08/2016

The impact of administration of conjugate vaccines containing cross reacting material on Haemophilus influenzae type b antibody responses in infants: A systematic review and meta-analysis of randomised controlled trials
Vaccine
Merryn Voysey and Manish Sadarangani and Elizabeth Clutterbuck and Barbara Bolgiano and Andrew J. Pollard
DOI: 10.1016/j.vaccine.2016.06.038
07/2016

Unusual cause of lymphangitis in a 2-year-old boy
BMJ Case Reports
Rhian Morgan and James Teh and Janet Craze and Manish Sadarangani
DOI: 10.1136/bcr-2016-215058
05/2016

A humanized microbiota mouse model of ovalbumin-induced lung inflammation
Gut Microbes
Marie-Claire Arrieta and Manish Sadarangani and Eric M. Brown and Shannon L. Russell and Michael Nimmo and John Dean and Stuart E. Turvey and Edmond S. Chan and B. Brett Finlay
DOI: 10.1080/19490976.2016.1182293
04/2016

Characterisation of the Immunomodulatory Effects of Meningococcal Opa Proteins on Human Peripheral Blood Mononuclear Cells and CD4+ T Cells
PLOS ONE
Claire Jones and Manish Sadarangani and Susan Lewis and Isabelle Payne and Muhammad Saleem and Jeremy P. Derrick and Andrew J. Pollard
DOI: 10.1371/journal.pone.0154153
04/2016

Anti-N-Methyl-D-Aspartate Receptor Encephalitis In A Young Child With Histological Evidence On Brain Biopsy Of Coexistent Herpes Simplex Virus Type 1 Infection
The Pediatric Infectious Disease Journal
Mark A. Ellul and Michael J. Griffiths and Anand Iyer and Shivaram Avula and Sylviane Defres and Atik Baborie and Angela Vincent and Natalie G. Martin and Manish Sadarangani and Andrew J. Pollard and Tom Solomon and Rachel Kneen
DOI: 10.1097/inf.0000000000001011
03/2016

Impact of Reducing Complement Inhibitor Binding on the Immunogenicity of Native Neisseria meningitidis Outer Membrane Vesicles
PLOS ONE
Helene Daniels-Treffandier and Karlijn de Nie and Leanne Marsay and Christina Dold and Manish Sadarangani and Arturo Reyes-Sandoval and Paul R. Langford and David Wyllie and Fergal Hill and Andrew J. Pollard and Christine S. Rollier
DOI: 10.1371/journal.pone.0148840
02/2016

Phase variation of Opa proteins of Neisseria meningitidis and the effects of bacterial transformation
Journal of Biosciences
Manish Sadarangani and J Claire Hoe and Katherine Makepeace and Peter van der Ley and Andrew J Pollard
DOI: 10.1007/s12038-016-9588-y
01/2016

Clinical aspects of meningococcal disease
Handbook of Meningococcal Disease Management
Stephen Pelton and Manish Sadarangani and Linda Glennie and Michael Levin
DOI: 10.1007/978-3-319-28119-3_5
2016

Can we control all-cause meningococcal disease in Europe?
Clinical Microbiology and Infection
Sadarangani, M. and Pollard, A.J.
DOI: 10.1016/j.cmi.2016.03.006
2016

Anti-N-methyl-d-aspartate receptor encephalitis in a young child with histological evidence on brain biopsy of coexistent herpes simplex virus type 1 infection
Pediatric Infectious Disease Journal
Ellul, M.A. and Griffiths, M.J. and Iyer, A. and Avula, S. and Defres, S. and Baborie, A. and Vincent, A. and Martin, N.G. and Sadarangani, M. and Pollard, A.J. and Solomon, T. and Kneen, R.
DOI: 10.1097/INF.0000000000001011
2016

Hospital admissions for viral meningitis in children in England over five decades: a population-based observational study
The Lancet Infectious Diseases
Martin, N.G. and Iro, M.A. and Sadarangani, M. and Goldacre, R. and Pollard, A.J. and Goldacre, M.J.
DOI: 10.1016/S1473-3099(16)30201-8
2016

I mmuno g lobuli N i n the T reatment of e ncephalitis (IgNiTE): Protocol for a multicentre randomised controlled trial
BMJ Open
Iro, M.A. and Sadarangani, M. and Absoud, M. and Chong, W.K. and Clark, C.A. and Easton, A. and Gray, V. and Kneen, R. and Lim, M. and Pike, M. and Solomon, T. and Vincent, A. and Willis, L. and Yu, L.-M. and Pollard, A.J.
DOI: 10.1136/bmjopen-2016-012356
2016

Handbook of meningococcal disease management
Handbook of Meningococcal Disease Management
Feavers, I. and Pollard, A.J. and Sadarangani, M.
DOI: 10.1007/978-3-319-28119-3
2016

Meningitis
Manual of Childhood Infections (4th edition)
2016

Response to Hepatitis B virus vaccine in young adults with perinatally acquired HIV infection
Journal of Infection
Manish Sadarangani and Herman Tam and Susan McDonald and Sarah Fidler and Caroline Foster
DOI: 10.1016/j.jinf.2015.06.003
10/2015

A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trial
Journal of Infection
L. Marsay and C. Dold and C.A. Green and C.S. Rollier and G. Norheim and M. Sadarangani and M. Shanyinde and C. Brehony and A.J. Thompson and H. Sanders and H. Chan and K. Haworth and J.P. Derrick and I.M. Feavers and M.C. Maiden and A.J. Pollard
DOI: 10.1016/j.jinf.2015.05.006
09/2015

Brain Abscesses Due to Aspergillus nidulans Infection During Induction Chemotherapy for Acute Lymphoblastic Leukemia
Journal of Pediatric Hematology/Oncology
Manish Sadarangani and Melissa Harvey and Allison McDonald and David P. Speert and David Dix
DOI: 10.1097/mph.0000000000000351
08/2015

Subacute Osteomyelitis of the Femur Due to Fusobacterium nucleatum in a 7-year-old Boy
The Pediatric Infectious Disease Journal
Emily Budd and David S. Johnson and Eva Thomas and Manish Sadarangani
DOI: 10.1097/inf.0000000000000558
03/2015

Outcomes of Invasive Meningococcal Disease in Adults and Children in Canada Between 2002 and 2011: A Prospective Cohort Study
Clinical Infectious Diseases
M. Sadarangani and D. W. Scheifele and S. A. Halperin and W. Vaudry and N. Le Saux and R. Tsang and J. A. Bettinger and investigators of the Canadian Immunization and N. Bridger and R. Morris and S. Halperin and K. Top and P. Dery and D. Moore and M. Lebel and N. Le Saux and D. Tran and L. Ford-Jones and J. Embree and B. Law and R. Tsang and B. Tan and W. Vaudry and T. Jadavji and O. G. Vanderkooi and D. Scheifele and L. Sauve and J. Bettinger and investigators of the Canadian Immunization
DOI: 10.1093/cid/civ028
01/2015

Meningococcus
Nelson Textbook of Pediatrics (20th edition)
2015

Brain Abscesses Due to Aspergillus nidulans Infection during Induction Chemotherapy for Acute Lymphoblastic Leukemia
Journal of Pediatric Hematology/Oncology
Sadarangani, M. and Harvey, M. and McDonald, A. and Speert, D.P. and Dix, D.
DOI: 10.1097/MPH.0000000000000351
2015

Subacute osteomyelitis of the femur due to Fusobacterium nucleatum in a 7-year-old boy
Pediatric Infectious Disease Journal
Budd, E. and Johnson, D.S. and Thomas, E. and Sadarangani, M.
DOI: 10.1097/INF.0000000000000558
2015

Childhood meningitis in the conjugate vaccine era: A prospective cohort study
Archives of Disease in Childhood
Sadarangani, M. and Willis, L. and Kadambari, S. and Gormley, S. and Young, Z. and Beckley, R. and Gantlett, K. and Orf, K. and Blakey, S. and Martin, N.G. and Kelly, D.F. and Heath, P.T. and Nadel, S. and Pollard, A.J.
DOI: 10.1136/archdischild-2014-306813
2015

The capsular group B meningococcal vaccine, 4CMenB: Clinical experience and potential efficacy
Expert Opinion on Biological Therapy
Rollier, C.S. and Dold, C. and Marsay, L. and Sadarangani, M. and Pollard, A.J.
DOI: 10.1517/14712598.2015.983897
2015

Hospital admission rates for meningitis and septicaemia caused by Haemophilus influenzae, Neisseria meningitidis, and Streptococcus pneumoniae in children in England over five decades: a population-based observational study
The Lancet Infectious Diseases
Natalie G Martin and Manish Sadarangani and Andrew J Pollard and Michael J Goldacre
DOI: 10.1016/s1473-3099(14)70027-1
05/2014

Association between population prevalence of smoking and incidence of meningococcal disease in Norway, Sweden, Denmark and the Netherlands between 1975 and 2009: a population-based time series analysis
BMJ Open
Gunnstein Norheim and Manish Sadarangani and Omar Omar and Ly-Mee Yu and Kåre Mølbak and Michael Howitz and Per Olcén and Margaretha Haglund and Arie van der Ende and Andrew J Pollard
DOI: 10.1136/bmjopen-2013-003312
02/2014

Long-Term Survival and Outcome in Children Admitted to Kilifi District Hospital with Convulsive Status Epilepticus
Epilepsy Research and Treatment
Agnes Prins and Eddie Chengo and Victor Mung'ala Odera and Manish Sadarangani and Claire Seaton and Penny Holding and Greg Fegan and Charles R. Newton
DOI: 10.1155/2014/643747
01/2014

Erratum: The role of the immune system in governing host-microbe interactions in the intestine (Nature Immunology (2013) 14 (660-667))
Nature Immunology
Brown, E.M. and Sadarangani, M. and Finlay, B.B.
DOI: 10.1038/ni0214-205d
2014

Neisseria meningitidis native outer membrane vesicles containing different lipopolysaccharide glycoforms as adjuvants for meningococcal and nonmeningococcal antigens
Clinical and Vaccine Immunology
Nagaputra, J.C. and Rollier, C.S. and Sadarangani, M. and Hoe, J.C. and Mehta, O.H. and Norheim, G. and Saleem, M. and Chan, H. and Derrick, J.P. and Feavers, I. and Pollard, A.J. and Moxon, E.R.
DOI: 10.1128/CVI.00561-13
2014

The impact of the meningococcal serogroup C conjugate vaccine in Canada between 2002 and 2012
Clinical Infectious Diseases
Sadarangani, M. and Scheifele, D.W. and Halperin, S.A. and Vaudry, W. and Saux, N.L. and Tsang, R. and Bettinger, J.A.
DOI: 10.1093/cid/ciu597
2014

Adjuvant effects elicited by novel oligosaccharide variants of detoxified meningococcal lipopolysaccharides on Neisseria meningitidis recombinant PorA protein: A comparison in mice
PLoS ONE
Mehta, O.H. and Norheim, G. and Hoe, J.C. and Rollier, C.S. and Nagaputra, J.C. and Makepeace, K. and Saleem, M. and Chan, H. and Ferguson, D.J.P. and Jones, C. and Sadarangani, M. and Hood, D.W. and Feavers, I. and Derrick, J.P. and Pollard, A.J. and Moxon, E.R.
DOI: 10.1371/journal.pone.0115713
2014

Hospital admission rates for meningitis and septicaemia caused by Haemophilus influenzae, Neisseria meningitidis, and Streptococcus pneumoniae in children in England over five decades: A population-based observational study
The Lancet Infectious Diseases
Martin, N.G. and Sadarangani, M. and Pollard, A.J. and Goldacre, M.J.
DOI: 10.1016/S1473-3099(14)70027-1
2014

Correction: Construction of Opa-Positive and Opa-Negative Strains of Neisseria meningitidis to Evaluate a Novel Meningococcal Vaccine.
PloS one
Sadarangani M and Hoe JC and Callaghan MJ and Jones C and Chan H and Makepeace K and Daniels-Treffandier H and Deadman ME and Bayliss C and Feavers I and van der Ley P and Pollard AJ
DOI: 10.1371/annotation/900641dd-0b06-4a77-9e2c-b7161dd49e1d
10/2013

The role of the immune system in governing host-microbe interactions in the intestine
Nature Immunology
Eric M Brown and Manish Sadarangani and B Brett Finlay
DOI: 10.1038/ni.2611
06/2013

Adolescents need a booster of serogroup C meningococcal vaccine to protect them and maintain population control of the disease
Archives of Disease in Childhood
A. J. Pollard and C. Green and M. Sadarangani and M. D. Snape
DOI: 10.1136/archdischild-2012-303103
03/2013

Neonatal Sepsis due to Coagulase-Negative Staphylococci
Clinical and Developmental Immunology
Elizabeth A. Marchant and Guilaine K. Boyce and Manish Sadarangani and Pascal M. Lavoie
DOI: 10.1155/2013/586076
2013

How best to describe the risk of meningococcal B infection?
Paediatrics and Child Health (Canada)
Sadarangani, M. and Bettinger, J.A. and Scheifele, D.W.
DOI: 10.1093/pch/18.10.543
2013

Neisseria meningitidis Native Outer Membrane Vesicles Containing Different Lipopolysaccharide Glycoforms as Adjuvants for Meningococcal and Nonmeningococcal Antigens
Clinical and Vaccine Immunology
Jerry C. Nagaputra and Christine S. Rollier and Manish Sadarangani and J. Claire Hoe and Ojas Hrakesh Mehta and Gunnstein Norheim and Muhammad Saleem and Hannah Chan and Jeremy P. Derrick and Ian Feavers and Andrew J. Pollard and E. Richard Moxon
DOI: 10.1128/cvi.00561-13
2013

Construction of Opa-Positive and Opa-Negative Strains of Neisseria meningitidis to Evaluate a Novel Meningococcal Vaccine
PLoS ONE
Manish Sadarangani and J. Claire Hoe and Martin J. Callaghan and Claire Jones and Hannah Chan and Katherine Makepeace and Hélène Daniels-Treffandier and Mary E. Deadman and Christopher Bayliss and Ian Feavers and Peter van der Ley and Andrew J. Pollard
DOI: 10.1371/journal.pone.0051045
2012

Bacterial Meningitis in Childhood
Hot Topics in Infection and Immunity in Children VIII
Manish Sadarangani and Andrew J. Pollard
DOI: 10.1007/978-1-4614-0204-6_16
09/2011

Opa proteins and CEACAMs: pathways of immune engagement for pathogenicNeisseria
FEMS Microbiology Reviews
Manish Sadarangani and Andrew J. Pollard and Scott D. Gray-Owen
DOI: 10.1111/j.1574-6976.2010.00260.x
05/2011

Acute seizures attributable to falciparum malaria in an endemic area on the Kenyan coast
Brain
Symon M. Kariuki and Michelle Ikumi and John Ojal and Manish Sadarangani and Richard Idro and Ally Olotu and Philip Bejon and James A. Berkley and Kevin Marsh and Charles R. J. C. Newton
DOI: 10.1093/brain/awr051
04/2011

Potential of Recombinant Opa Proteins as Vaccine Candidates against Hyperinvasive Meningococci
Infection and Immunity
M. J. Callaghan and S. Lewis and M. Sadarangani and S. E. S. Bailey and H. Chan and D. J. P. Ferguson and J. P. Derrick and I. Feavers and M. C. Maiden and A. J. Pollard
DOI: 10.1128/iai.01338-10
04/2011

Meningitis
Manual of Childhood Infections (3rd edition)
2011

Potential of recombinant opa proteins as vaccine candidates against hyperinvasive meningococci
Infection and Immunity
Callaghan, M.J. and Lewis, S. and Sadarangani, M. and Bailey, S.E.S. and Chan, H. and Ferguson, D.J.P. and Derrick, J.P. and Feavers, I. and Maiden, M.C. and Pollard, A.J.
DOI: 10.1128/IAI.01338-10
2011

Serogroup B meningococcal vaccines—an unfinished story
The Lancet Infectious Diseases
Manish Sadarangani and Andrew J Pollard
DOI: 10.1016/s1473-3099(09)70324-x
02/2010

Serogroup B meningococcal vaccines-an unfinished story
The Lancet Infectious Diseases
Sadarangani, M. and Pollard, A.J.
DOI: 10.1016/S1473-3099(09)70324-X
2010

An observational study of children with sickle cell disease in Kilifi, Kenya
British Journal of Haematology
Manish Sadarangani and Julie Makani and Albert N. Komba and Tolu Ajala-Agbo and Charles R. Newton and Kevin Marsh and Thomas N. Williams
DOI: 10.1111/j.1365-2141.2009.07771.x
09/2009

Malaria as a Cause of Morbidity and Mortality in Children with Homozygous Sickle Cell Disease on the Coast of Kenya
Clinical Infectious Diseases
Albert N. Komba and Julie Makani and Manish Sadarangani and Tolu Ajala-Agbo and James A. Berkley and Charles R. J. C. Newton and Kevin Marsh and Thomas N. Williams
DOI: 10.1086/599834
07/2009

Challenges and progress in the development of a serogroup B meningococcal vaccine
Expert Review of Vaccines
Susan Lewis and Manish Sadarangani and J Claire Hoe and Andrew J Pollard
DOI: 10.1586/erv.09.30
06/2009

Role of Acquired Immunity in Neisseria Infections
Neisseria: Molecular Mechanisms of Pathogenesis
2009

Incidence and outcome of convulsive status epilepticus in Kenyan children: a cohort study
The Lancet Neurology
Manish Sadarangani and Claire Seaton and J Anthony G Scott and Bernhards Ogutu and Tansy Edwards and Agnes Prins and Hellen Gatakaa and Richard Idro and James A Berkley and Norbert Peshu and Brian G Neville and Charles R Newton
DOI: 10.1016/s1474-4422(07)70331-9
02/2008

Incidence and outcome of convulsive status epilepticus in Kenyan children: a cohort study
The Lancet Neurology
Sadarangani, M. and Seaton, C. and Scott, J.A.G. and Ogutu, B. and Edwards, T. and Prins, A. and Gatakaa, H. and Idro, R. and Berkley, J.A. and Peshu, N. and Neville, B.G. and Newton, C.R.
DOI: 10.1016/S1474-4422(07)70331-9
2008

An analysis of herpes simplex virus gene expression during latency establishment and reactivation.
Journal of General Virology
R H Lachmann and S Efstathiou and M Sadarangani and H R Atkinson
DOI: 10.1099/0022-1317-80-5-1271
05/1999

Research

Vaccine Evaluation Center
Please see the Vaccine Evaluation Center's research: https://bcchr.ca/vec/research.

Research Group Members

Kyle Amaral, Master's of Experimental Medicine
Kevin Atkins
Wayne Bao
Sara Belga
Leonora Beltran
Lisa Blackwell, Research Nurse
Lizl Bonifacio, Work Learn Student
Adriana Cabrera, Research Technician at Sadarangani Lab Canadian Burkholderia cepacia Complex Research and Referral Repository (CBCCRRR) technician
Natalie Cavallin, Medical Student
Anita Chiu
Melissa Chiu, Undergraduate Medical Student
Tinta Deasy, Pediatric Fellow
Mahin Delara
Catie Futhey
Gabrielle Gaultier, Postdoctoral Fellow
Vivek Gill, Research Assistant
Engy Grove
Rafid Haq
Tony Harn, Research Technician
Hala Hasan
Olivia Hunter
Kendrix Kek, Bioninformatician
Amy Lee, Research Assistant
Ian Lin, Volunteer
Suzanne Liu, Statistician
Ashley Low
Sue Lu, Research Assistant/ Co-op Student
Michelle Luk, Research Administrator
Elle MacLennan
Jennifer Mark, Research Coordinator
Matthew Marty
Emily Mason
Miriam Maude Verly
Grace McCauley, Data Coordinator
Brynn Mcmillan, Research Staff
Kevin Meesters, Pediatric ID Fellow
Mona Mohammadnia
Estelle Morin
Liam Mullins, MSc Student
Yvonne Nguyen, Work Learn Student
Imogen Porter
Sarai Racey, Research Associate
Bernice Ramos, Graduate Research Assistant
Hannah Robinson
Brittany Seligman, clinical research coordinator
Robert Shen
Hennady Shulha
Danielle Sidsworth, Medical Student
Sarah Silverberg, Clinical Trainee
Karen Simmons, Research Administrator
Kelly Simmons, Research Nurse
Nirma Vadlamudi, Postdoctoral Fellow
Catherine Wang
Betty Wong, Research Administrator
Kendrew Wong, Coop Student - Medicine
Cecilia Yang
Tian Zhao, Research Assistant/ Co-op student
James Zlosnik, Research Associate - Chronic Bacterial Infections in Cystic Fibrosis. Primary Scientist and Manager - Canadian Burkholderia Cepacia Complex research Referral Repository. Project Manager - Centre for Understanding and Preventing Infection in Children. , Research Associate - Chronic Bacterial Infections in Cystic Fibrosis. Primary Scientist and Manager - Canadian Burkholderia Cepacia Complex research Referral Repository. Project Manager - Centre for Understanding and Preventing Infection in Children.