Bruce Bjornson
FRCPC, MD, BSc (Med)
Investigator, BC Children's Hospital Research Insitute
Medical Director, Brain Mapping, Neuroinformatics & Neurotechnology Laboratory
Investigator, BC Children's Hospital Research Insitute
Consensus recommendations for clinical functional MRI applied to language mapping.
Aperture neuro
Voets NL and Ashtari M and Beckmann CF and Benjamin CF and Benzinger T and Binder JR and Bizzi A and Bjornson B and Chang EF and Douw L and Gawryluk J and Geletneky K and Glasser MF and Haller S and Jenkinson M and Jovicich J and Leuthardt E and Mian A and Nichols TE and Jones OP and Pernet C and Plaha P and Polczynska-Bletsos M and Price CJ and Rutten GJ and Scheel M and Shimony JS and Sierpowska J and Williams LJ and Talib G and Zeineh M and Bartsch A and Bookheimer S
DOI: 10.52294/001c.128149 PubMed: 4242255301 / 2025
Diagnostic Yield and Treatment Impact of Targeted Exome Sequencing in Early-Onset Epilepsy.
Frontiers in neurology
Demos M and Guella I and DeGuzman C and McKenzie MB and Buerki SE and Evans DM and Toyota EB and Boelman C and Huh LL and Datta A and Michoulas A and Selby K and Bjornson BH and Horvath G and Farrer MJ
DOI: 10.3389/fneur.2019.00434 PubMed: 3116485805 / 2019
Advancing Concussion Assessment in Pediatrics (A-CAP): A prospective, concurrent cohort, longitudinal study of mild traumatic brain injury in children: Protocol study
BMJ Open
Yeates, K.O. and Beauchamp, M. and Craig, W. and Doan, Q. and Zemek, R. and Bjornson, B. and Gravel, J. and Mikrogianakis, A. and Goodyear, B. and Abdeen, N. and Beaulieu, C. and Dehaes, M. and Deschenes, S. and Harris, A. and Lebel, C. and Lamont, R. and Williamson, T. and Barlow, K.M. and Bernier, F. and Brooks, B.L. and Emery, C. and Freedman, S.B. and Kowalski, K. and Mrklas, K. and Tomfohr-Madsen, L. and Schneider, K.J.
DOI: 10.1136/bmjopen-2017-017012Epidemiology and Outcomes of Arterial Ischemic Stroke in Children: The Canadian Pediatric Ischemic Stroke Registry
Pediatric Neurology
deVeber, G.A. and Kirton, A. and Booth, F.A. and Yager, J.Y. and Wirrell, E.C. and Wood, E. and Shevell, M. and Surmava, A.-M. and McCusker, P. and Massicotte, M.P. and MacGregor, D. and MacDonald, E.A. and Meaney, B. and Levin, S. and Lemieux, B.G. and Jardine, L. and Humphreys, P. and David, M. and Chan, A.K.C. and Buckley, D.J. and Bjornson, B.H.
DOI: 10.1016/j.pediatrneurol.2017.01.016Harnessing Neuroimaging Capability in Pediatric Stroke: Proceedings of the Stroke Imaging Laboratory for ChildrenWorkshop
Pediatric Neurology
Dlamini, N. and Wintermark, M. and Fullerton, H. and Strother, S. and Lee, W. and Bjornson, B. and Guilliams, K.P. and Miller, S. and Kirton, A. and Filippi, C.G. and Linds, A. and Askalan, R. and deVeber, G.
DOI: 10.1016/j.pediatrneurol.2017.01.006The effects of pediatric epilepsy on a language connectome
Human Brain Mapping
Eddin, A.S. and Wang, J. and Wu, W. and Sargolzaei, S. and Bjornson, B. and Jones, R.A. and Gaillard, W.D. and Adjouadi, M.
DOI: 10.1002/hbm.22600Classification of FMRI patterns-A study of the language network segregation in pediatric localization related epilepsy
Human Brain Mapping
Wang, J. and You, X. and Wu, W. and Guillen, M.R. and Cabrerizo, M. and Sullivan, J. and Donner, E. and Bjornson, B. and Gaillard, W.D. and Adjouadi, M.
DOI: 10.1002/hbm.22265Cerebellar language mapping and cerebral language dominance in pediatric epilepsy surgery patients
NeuroImage: Clinical
Gelinas, J.N. and Fitzpatrick, K.P.V. and Kim, H.C. and Bjornson, B.H.
DOI: 10.1016/j.nicl.2014.06.016A decisional space for fMRI pattern separation using the principal component analysis-a comparative study of language networks in pediatric epilepsy
Human Brain Mapping
You, X. and Adjouadi, M. and Wang, J. and Guillen, M.R. and Bernal, B. and Sullivan, J. and Donner, E. and Bjornson, B. and Berl, M. and Gaillard, W.D.
DOI: 10.1002/hbm.22069Serial monitoring of CO2 reactivity following sport concussion using hypocapnia and hypercapnia
Brain Injury
Len, T.K. and Neary, J.P. and Asmundson, G.J.G. and Candow, D.G. and Goodman, D.G. and Bjornson, B. and Bhambhani, Y.N.
DOI: 10.3109/02699052.2012.743185Sub-patterns of language network reorganization in pediatric localization related epilepsy: A multisite study
Human Brain Mapping
You, X. and Adjouadi, M. and Guillen, M.R. and Ayala, M. and Barreto, A. and Rishe, N. and Sullivan, J. and Dlugos, D. and Vanmeter, J. and Morris, D. and Donner, E. and Bjornson, B. and Smith, M.L. and Bernal, B. and Berl, M. and Gaillard, W.D.
DOI: 10.1002/hbm.21066Cerebrovascular reactivity impairment after sport-induced concussion
Medicine and Science in Sports and Exercise
Len, T.K. and Neary, J.P. and Asmundson, G.J.G. and Goodman, D.G. and Bjornson, B. and Bhambhani, Y.N.
DOI: 10.1249/MSS.0b013e3182249539Male predominance in childhood ischemic stroke: findings from the international pediatric stroke study.
Golomb MR and Fullerton HJ and Nowak-Gottl U and Deveber G and International Pediatric Stroke Study Group
DOI: 10.1161/strokeaha.108.521203 PubMed: 1878719701 / 2009
Combined functional MRI and diffusion tensor imaging analysis of visual motion pathways
Journal of Neuro-Ophthalmology
Lanyon, L.J. and Giaschi, D. and Young, S.A. and Fitzpatrick, K. and Diao, L. and Bjornson, B.H. and Barton, J.J.S.
DOI: 10.1097/WNO.0b013e3181a58ef8Pediatric functional imaging consortium: sub-patterns of language dominance in pediatric localization related epilepsy identified by data driven separation analysis
EPILEPSIA
GAILLARD, WD and YOU, X and BERNAL, B and GUILLEN, MR and AYALA, M and JAYAKAR, P and BARRETO, A and RISHE, N and SULLIVAN, J and DLUGOS, D and BERL, MM and VANMETER, J and MORRIS, D and DONNER, E and BJORNSON, B and SMITH, M and ADJOUADI, M
Presurgical Visualization of Cerebral Surface Veins with Susceptibility Weighted Imaging
17th Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)
Anti-basal ganglia antibodies and acute movement disorder following herpes zoster and streptococcal infections
European Journal of Paediatric Neurology
Basheer, S.N. and Wadsworth, L.D. and Bjornson, B.H.
DOI: 10.1016/j.ejpn.2006.11.001Simultaneous registration and activation detection for fMRI
IEEE Transactions on Medical Imaging
Orchard, J. and Greif, C. and Golub, G.H. and Bjornson, B. and Atkins, M.S.
DOI: 10.1109/TMI.2003.819294Hemispheric dissociation of verb generation from verb reading: functional MRI of an adolescent with early left MCA infraction
NEUROIMAGE
BJORNSON, B and GIASCHI, D and SLICK, D and CONNOLLY, M and YOUNG, SA
Hemispheric dissociation of verb generation from verb reading: functional MRI of an adolescent with early left MCA infarction
NEUROIMAGE
BJORNSON, B and GIASCHI, D and SLICK, D and CONNOLLY, M and YOUNG, SA
DOI: 10.1016/S1053-8119(01)91851-8Cerebral sinovenous thrombosis in children
New England Journal of Medicine
DeVeber, G. and Andrew, M. and Adams, C. and Bjornson, B. and Booth, F. and Buckley, D.J. and Camfield, C.S. and David, M. and Humphreys, P. and Langevin, P. and MacDonald, E.A. and Gillett, J.
DOI: 10.1056/NEJM200108093450604High resolution EEG & seizure localization
NeuroImage
Wong, P.K.H. and Bjornson, B. and Connolly, M. and Steinbok, P. and Young, S.A. and Giaschi, D. and Gregory, D. and Smith, S. and Lee, R. and Man, A. and Cochrane, D.
Non-invasive mapping of sensorimotor cortex in a child with a cavernous angioma: FMRI and high-resolution EEG compared with surgical mapping
NeuroImage
Bjornson, B. and Giaschi, D. and Cochrane, D. and Au Young, S. and Rootman, D. and Boden, C. and Connolly, M. and Poskitt, K. and Boyle, C. and Smith, S. and Akagemi, R. and Wong, P.K.H.
Dichotic pitch
NeuroReport
Robert F. Dougherty and Max S. Cynader and Bruce H. Bjornson and Dorothy Edgell and Deborah E. Giaschi
DOI: 10.1097/00001756-199809140-00015 PubMed: 980430509 / 1998
Comparison of visual activation measured by fMRI and high resolution EEG
NeuroImage
Dougherty, R.F. and Au Young, S.M.W. and Giaschi, D.E. and Bjornson, B.H. and Wong, P.K.H.
Dichotic pitch: A new stimulus distinguishes normal and dyslexic auditory function
NeuroReport
Dougherty, R.F. and Cynader, M.S. and Bjornson, B.H. and Edgell, D. and Giaschi, D.E.
Ictal and interictal technetium-99m-bicisate brain SPECT in children with refractory epilepsy.
Packard AB and Roach PJ and Davis RT and Carmant L and Davis R and Riviello J and Holmes G and Barnes PD and O'Tuama LA and Bjornson B and Treves ST
PubMed: 896517707 / 1996
Ictal and interictal technetium-99m-bicisate brain SPECT in children with refractory epilepsy
Journal of Nuclear Medicine
Packard, A.B. and Roach, P.J. and Davis, R.T. and Carmant, L. and Davis, R. and Riviello, J. and Holmes, G. and Barnes, P.D. and O'Tuama, L.A. and Bjornson, B. and Treves, S.T.
PubMed: 8965177Cerebral infarction in childhood: is the left hemisphere more susceptible to ischemic injury?
30th Meeting of the Canadian Congress of Neurological Sciences
DOI: 10.1017/s031716710003939106 / 1995
Brain
Pediatric Nuclear Medicine, Second Edition
L. A. O'Tuama and B. Bjornson and H. Chugani and S. T. Treves
DOI: 10.1007/978-1-4757-4205-3_6Regional cerebral perfusion in Landau-Kleffner syndrome and related childhood aphasias.
O'Tuama LA and Urion DK and Janicek MJ and Treves ST and Bjornson B and Moriarty JM
PubMed: 138347810 / 1992
Regional cerebral perfusion in Landau-Kleffner syndrome and related childhood aphasias
Journal of Nuclear Medicine
O'Tuama, L.A. and Urion, D.K. and Janicek, M.J. and Treves, S.T. and Bjornson, B. and Moriarty, J.M.
PubMed: 1383478IPSS Study - International Paediatric Stroke Study
We aim to obtain preliminary data from large multi-center studies assessing sub-types, outcomes and current treatments for newborns and children with stroke. Due to the relative rarity of childhood stoke, sufficient numbers of patients to provide the necessary power can only be achieved with multi-center and multi-national approaches. The overall objective is to develop and conduct clinical trials in childhood stroke.
The specific aims are:
Ascertain in a prospective cohort study, the numbers of newborns and children with ischemic stroke, their stroke sub-types and risk factors, their current treatments and outcomes within the participating centers. These data will provide the rationale and feasibility data for the study group to design and implement the initial RCT’s in paediatric stroke as well as other fundable grant proposals.
Develop and institute standardized protocols for (1) diagnosis, (2) investigation of risk factors, (3) antithrombotic therapies and (4) outcome assessment of neonates and children with arterial ischemic stroke and sinovenous thrombosis
Develop standardized data forms and an appropriate database with web-based data entry from multiple study sites.
Submit successful grant applications for additional funding of IPSS multi-centre studies.
This prospective study enrolls newborns and children with ischemic stroke born at or referred to BC Children’s Hospital. These newborns are then followed at 3 and 12 months post stroke.
fMRI Study - Multi-Site Pediatric Network for fMRI Mapping in Childhood Epilepsy
We aim to establish the utility of functional Magnetic Resonance Imaging (fMRI) in identifying atypical language in childhood localization related epilepsy, by using a variety of language paradigms that have already been tested in normal children and patients with epilepsy.
The study objectives include:
To establish the network infrastructure for multi-site collection and management of functional imaging data linked to a database of common assessments and measures
To establish the feasibility of conducting multi-site fMRI by identifying patients with atypical language, and to provide pilot data necessary to conduct a large scale study to compare fMRI findings to invasive methods (IAT, ECS, surgical outcome)
To achieve this goals, an imaging consortium with web based access and central data storage will be established. A multi-centre, cross sectional prospective study will use fMRI to study patients undergoing epilepsy surgery. Clinical data will be collected as part of routine evaluation for chronic epilepsy in children considered for epilepsy surgery.
Honours & Awards
Farley Fellowship (Children's Hospital, Boston), 1992
University of Alberta Alumni Association Award , 1977
Adella Patridge Award for Cardiology (University of Alberta), 1981
Von Meyer Travelling Award (Children's Hospital, Boston), 1991
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