Overview

My focus is in the treatment and long term outcomes of children treated for cancer. My specific focus is in quantifying what complications are seen in survivors of childhood cancer. Specifically, I am interested in trying to identify genetic markers that may identify those who are at risk of a specific complication. We are currently in the process of identifying genes that may explain why 20-50% of children receiving cisplatin have irreversible hearing loss. We have established a database of all adverse events in children treated through the oncology department at BC Children's Hospital. I am also interested in using linked databases to look at hospital utilization in long term survivors. Finally, I am interested in developing clinical trials in pediatric oncology both locally, as well as through the Children's Oncology Group (COG).

Publications

Genomic variations associated with risk and protection against vincristine-induced peripheral neuropathy in pediatric cancer patients
npj Genomic Medicine
Kheireddin Mufti and Miguel Cordova and Erika N. Scott and Jessica N. Trueman and Jessica M. Lovnicki and Catrina M. Loucks and Shahrad R. Rassekh and Colin J. D. Ross and Bruce C. Carleton and Gabriella S. S. Groeneweg and Michelle Higginson and Wan-Chun Chang and Kathy Li and Fudan Miao and Derek Yau and Lucie Pecheux and Bina Gyawali and Amanda Perreault and Fatema Abbasi and Gregory Guilcher and Gesche Riabowol and Geert ’t Jong and Michelle Staub and Geoff Cuvelier and Kathleen Felton and Sara Khalaj and Michael Rieder and Awatif Abuzgaia and Tamorah Lewis and Himal Ghimire and Paul Nathan and Donna Johnston and Mounira Ibrahim and Jean-François Bussières and Thaïna-Rafi Jean-Baptiste and Denis Lebel and Maja Krajinovic and Thai Hoa Tran and Kerry Goralski and Zara Forbrigger and Ketan Kulkarni
DOI: 10.1038/s41525-024-00443-7
11/2024

Supplementary Fig. 3 from INTRAVENOUS N-ACETYLCYSTEINE TO PREVENT CISPLATIN-INDUCED HEARING LOSS IN CHILDREN: A NONRANDOMIZED CONTROLLED PHASE 1 TRIAL
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin JD. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.27031414.v1
09/2024

Data from INTRAVENOUS N-ACETYLCYSTEINE TO PREVENT CISPLATIN-INDUCED HEARING LOSS IN CHILDREN: A NONRANDOMIZED CONTROLLED PHASE 1 TRIAL
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin JD. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.c.6664582.v3
09/2024

Supplementary Fig. 5 from INTRAVENOUS N-ACETYLCYSTEINE TO PREVENT CISPLATIN-INDUCED HEARING LOSS IN CHILDREN: A NONRANDOMIZED CONTROLLED PHASE 1 TRIAL
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin JD. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.27031408
09/2024

Supplementary Fig. 4 from INTRAVENOUS N-ACETYLCYSTEINE TO PREVENT CISPLATIN-INDUCED HEARING LOSS IN CHILDREN: A NONRANDOMIZED CONTROLLED PHASE 1 TRIAL
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin JD. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.27031411
09/2024

Supplementary Fig. 2 from INTRAVENOUS N-ACETYLCYSTEINE TO PREVENT CISPLATIN-INDUCED HEARING LOSS IN CHILDREN: A NONRANDOMIZED CONTROLLED PHASE 1 TRIAL
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin JD. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.27031417
09/2024

Supplementary Fig. 1 from INTRAVENOUS N-ACETYLCYSTEINE TO PREVENT CISPLATIN-INDUCED HEARING LOSS IN CHILDREN: A NONRANDOMIZED CONTROLLED PHASE 1 TRIAL
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin JD. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.27031420
09/2024

Supplementary Data 1 from INTRAVENOUS N-ACETYLCYSTEINE TO PREVENT CISPLATIN-INDUCED HEARING LOSS IN CHILDREN: A NONRANDOMIZED CONTROLLED PHASE 1 TRIAL
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin JD. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.27031423
09/2024

Impact of dexamethasone on transplant-related mortality in pediatric patients: a multi-site, propensity score–weighted, retrospective assessment
Supportive Care in Cancer
DOI: 10.1007/s00520-024-08732-8
2024

Tubular Injury Biomarkers to Predict CKD and Hypertension at 3 Months Post-Cisplatin in Children
Kidney360
DOI: 10.34067/KID.0000000000000448
2024

Efficacy of Palivizumab Immunoprophylaxis for Reducing Severe RSV Outcomes in Children with Immunodeficiencies: A Systematic Review
Journal of the Pediatric Infectious Diseases Society
DOI: 10.1093/jpids/piae004
2024

Urinary TIMP-2*IGFBP-7 to diagnose acute kidney injury in children receiving cisplatin
Pediatric Nephrology
Chui, H. and McMahon, K.R. and Rassekh, S.R. and Schultz, K.R. and Blydt-Hansen, T.D. and Mammen, C. and Pinsk, M. and Cuvelier, G.D.E. and Carleton, B.C. and Tsuyuki, R.T. and Ross, C.J.D. and Devarajan, P. and Huynh, L. and Yordanova, M. and Cr{\'e}peau-Hubert, F. and Wang, S. and Cockovski, V. and Palijan, A. and Zappitelli, M.
DOI: 10.1007/s00467-023-06007-8
2024

Intra-arterial methylprednisolone for pediatric gastrointestinal post-transplant lymphoproliferative disorder
Pediatric Hematology and Oncology
DOI: 10.1080/08880018.2023.2267612
2024

Whole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers
Nature Communications
DOI: 10.1038/s41467-024-48363-5
2024

True Rate of Allergy among Pediatric Inpatients with Penicillin Allergy Labels (TRIAL)
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.3531
2024

Removing barriers to accessing medical cannabis for paediatric patients
Paediatrics and Child Health (Canada)
DOI: 10.1093/pch/pxac129
2024

Supplementary Fig. 4 from Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin J.D. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.23627138
07/2023

Supplementary Fig. 5 from Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin J.D. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.23627135
07/2023

Supplementary Fig. 3 from Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin J.D. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.23627141.v1
07/2023

Data from Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin J.D. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.c.6664582.v2
07/2023

Supplementary Data 1 from Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin J.D. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.23183878.v1
05/2023

Supplementary Fig. 2 from Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin J.D. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.23183872.v1
05/2023

Supplementary Fig. 1 from Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial
Etan Orgel and Kristin R. Knight and Yueh-Yun Chi and Jemily Malvar and Teresa Rushing and Victoria Mena and Laurie S. Eisenberg and Shahrad R. Rassekh and Colin J.D. Ross and Erika N. Scott and Michael Neely and Edward A. Neuwelt and Leslie L. Muldoon and David R. Freyer
DOI: 10.1158/1078-0432.23183875.v1
05/2023

Cannabinoids for symptom management in children with cancer: A systematic review and meta-analysis
Cancer
Chhabra, M. and Ben-Eltriki, M. and Paul, A. and M{\^e}-Linh, L.{\^E}. and Herbert, A. and Oberoi, S. and Bradford, N. and Bowers, A. and Rassekh, S.R. and Kelly, L.E.
DOI: 10.1002/cncr.34920
2023

RBL2 Regulates Cardiac Sensitivity to Anthracycline Chemotherapy
JACC: CardioOncology
Xia, P. and Chen, J. and Sapkota, Y. and Scott, E.N. and Liu, Y. and Hudson, M.M. and Rassekh, S.R. and Carleton, B.C. and Ross, C.J.D. and Chow, E.J. and Cheng, Z.
DOI: 10.1016/j.jaccao.2022.10.017
2023

Outcomes of a radiation sparing approach in medulloblastoma by subgroup in young children: an institutional review
Child's Nervous System
DOI: 10.1007/s00381-023-05918-z
2023

La pharmacothérapie en fonction des gènes
Paediatrics and Child Health (Canada)
Rassekh, S.R. and Rieder, M. and Jong, G.
DOI: 10.1093/pch/pxad001
2023

Gene-based drug therapy in children
Paediatrics and Child Health (Canada)
Rassekh, S.R. and Rieder, M. and Jong, G.
DOI: 10.1093/pch/pxad002
2023

Cisplatin-induced nephrotoxicity in childhood cancer: comparison between two countries
Pediatric Nephrology
Zazuli, Z. and Op ?t Hoog, C.J.P. and Vijverberg, S.J.H. and Masereeuw, R. and Rassekh, S.R. and Medeiros, M. and Rivas-Ruiz, R. and Maitland-van der Zee, A.H. and Carleton, B.C.
DOI: 10.1007/s00467-022-05632-z
2023

Acute kidney injury during cisplatin therapy and associations with kidney outcomes 2 to 6 months post-cisplatin in children: a multi-centre, prospective observational study
Pediatric Nephrology
McMahon, K.R. and Lebel, A. and Rassekh, S.R. and Schultz, K.R. and Blydt-Hansen, T.D. and Cuvelier, G.D.E. and Mammen, C. and Pinsk, M. and Carleton, B.C. and Tsuyuki, R.T. and Ross, C.J.D. and Huynh, L. and Yordanova, M. and Crépeau-Hubert, F. and Wang, S. and Palijan, A. and Lee, J. and Boyko, D. and Zappitelli, M.
DOI: 10.1007/s00467-022-05745-5
2023

Outcomes of Coronavirus Disease 2019 Infection in Children and Adolescents With Cancer in Canada: Population-based Study and Systematic Review
Journal of Pediatric Hematology/Oncology
Mark, C. and Gibson, P. and Lafay-Cousin, L. and Martin, G. and Oberoi, S. and Pecheux, L. and Rassekh, S.R. and Zorzi, A. and Alexander, S. and Gupta, S.
DOI: 10.1097/MPH.0000000000002644
2023

Role of Cisplatin Dose Intensity and TPMT Variation in the Development of Hearing Loss in Children
Therapeutic Drug Monitoring
Siemens, A. and Brooks, B. and Rassekh, S.R. and Meijer, A.J.M. and Van Den Heuvel-Eibrink, M.M. and Xu, W. and Loucks, C.M. and Ross, C.J.D. and Carleton, B.C.
DOI: 10.1097/FTD.0000000000001085
2023

Whole genome transcriptome analysis in a case of a neonatal soft tissue sarcoma with YWHAE:NUTM2B fusion
Pediatric Blood and Cancer
Locke, A. and Terry, J. and Shen, Y. and Courtemanche, D. and Rosenbaum, D.G. and Rassekh, S.R. and Deyell, R.J. and Cheng, S.
DOI: 10.1002/pbc.30310
2023

Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial
Clinical cancer research : an official journal of the American Association for Cancer Research
Orgel, E. and Knight, K.R. and Chi, Y.-Y. and Malvar, J. and Rushing, T. and Mena, V. and Eisenberg, L.S. and Rassekh, S.R. and Ross, C.J.D. and Scott, E.N. and Neely, M. and Neuwelt, E.A. and Muldoon, L.L. and Freyer, D.R.
DOI: 10.1158/1078-0432.CCR-23-0252
2023

Development of a Dose-Adjusted Polygenic Risk Model for Anthracycline-Induced Cardiotoxicity
Therapeutic Drug Monitoring
Siemens, A. and Rassekh, S.R. and Ross, C.J.D. and Carleton, B.C.
DOI: 10.1097/FTD.0000000000001077
2023

Medicinal cannabis in children and adolescents with autism spectrum disorder: A scoping review
Child: Care, Health and Development
Sarah Fletcher and Colleen Pawliuk and Angie Ip and Linda Huh and S. Rod Rassekh and Tim F. Oberlander and Harold Siden
DOI: 10.1111/cch.12909
01/2022

A Systematic Review of Polygenic Models for Predicting Drug Outcomes
Journal of Personalized Medicine
Siemens, A. and Anderson, S.J. and Rassekh, S.R. and Ross, C.J.D. and Carleton, B.C.
DOI: 10.3390/jpm12091394
2022

Clinician views on and ethics priorities for authorizing medical cannabis in the care of children and youth in Canada: a qualitative study
CMAJ open
Gunning, M. and Rotenberg, A.D. and Kelly, L.E. and Crooks, B. and Oberoi, S. and Rapoport, A.L. and Rassekh, S.R. and Illes, J.
DOI: 10.9778/cmajo.20210239
2022

Urine Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 to Detect Pediatric Cisplatin-Associated Acute Kidney Injury
Kidney360
Mcmahon, K.R. and Chui, H. and Rassekh, S.R. and Schultz, K.R. and Blydt-Hansen, T.D. and Mammen, C. and Pinsk, M. and Cuvelier, G.D.E. and Carleton, B.C. and Tsuyuki, R.T. and Ross, C.J.D. and Devarajan, P. and Huynh, L. and Yordanova, M. and Cr{\'e}peau-Hubert, F. and Wang, S. and Cockovski, V. and Palijan, A. and Zappitelli, M.
DOI: 10.34067/KID.0004802021
2022

Neither the “Devil’s Lettuce” nor a “Miracle Cure:” The Use of Medical Cannabis in the Care of Children and Youth
Neuroethics
Gunning, M. and Rotenberg, A. and Anderson, J. and Balneaves, L.G. and Brace, T. and Crooks, B. and Hall, W. and Kelly, L.E. and Rassekh, S.R. and Rieder, M. and Virani, A. and Ware, M.A. and Zaslawski, Z. and Siden, H. and Illes, J.
DOI: 10.1007/s12152-022-09478-y
2022

A pharmacogenomic investigation of the cardiac safety profile of ondansetron in children and pregnant women
Biomedicine and Pharmacotherapy
Drögemöller, B.I. and Wright, G.E.B. and Trueman, J. and Shaw, K. and Staub, M. and Chaudhry, S. and Miao, F. and Higginson, M. and Groeneweg, G.S.S. and Brown, J. and Magee, L.A. and Whyte, S.D. and West, N. and Brodie, S.M. and Jong, G.?. and Israels, S. and Berger, H. and Ito, S. and Rassekh, S.R. and Sanatani, S. and Ross, C.J.D. and Carleton, B.C.
DOI: 10.1016/j.biopha.2022.112684
2022

Pharmacogenetic testing to guide therapeutic decision-making and improve outcomes for children undergoing anthracycline-based chemotherapy
Basic and Clinical Pharmacology and Toxicology
Loucks, C.M. and Yan, K. and Tanoshima, R. and Ross, C.J.D. and Rassekh, S.R. and Carleton, B.C.
DOI: 10.1111/bcpt.13593
2022

Perspectives of pediatric oncologists and palliative care physicians on the therapeutic use of cannabis in children with cancer
Cancer Reports
Oberoi, S. and Protudjer, J.L.P. and Rapoport, A. and Rassekh, S.R. and Crooks, B. and Siden, H. and Decker, K. and Ananth, P. and Chapman, S. and Balneaves, L.G. and Vanan, M.I. and Kelly, L.E.
DOI: 10.1002/cnr2.1551
2022

The cumulative incidence of cisplatin-induced hearing loss in young children is higher and develops at an early stage during therapy compared with older children based on 2052 audiological assessments
Cancer
Meijer, A.J.M. and Li, K.H. and Brooks, B. and Clemens, E. and Ross, C.J. and Rassekh, S.R. and Hoetink, A.E. and van Grotel, M. and van den Heuvel-Eibrink, M.M. and Carleton, B.C.
DOI: 10.1002/cncr.33848
2022

Trametinib therapy for children with neurofibromatosis type 1 and life-threatening plexiform neurofibroma or treatment-refractory low-grade glioma
Cancer Medicine
Rebecca Ronsley and Celine D. Hounjet and Sylvia Cheng and Shahrad Rod Rassekh and Walter J. Duncan and Christopher Dunham and Jane Gardiner and Arvindera Ghag and Jeffrey P. Ludemann and David Wensley and Wingfield Rehmus and Michael A. Sargent and Juliette Hukin
DOI: 10.1002/cam4.3910
06/2021

Deliberations about clinical pharmacogenetic testing in pediatric oncology
Personalized Medicine
Issa, A.M. and Aboushawareb, S.A.E. and Eisenstat, D.D. and Guilcher, G.M.T. and Liu, G. and Rassekh, S.R. and Strahlendorf, C. and Tallen, G. and Tanoshima, R. and Carleton, B.
DOI: 10.2217/pme-2020-0120
2021

Vertebroplasty as a palliative treatment option for intractable pain in pediatric patients with spinal tumors
Pediatric Blood and Cancer
Cardarelli-Leite, L. and Rassekh, S.R. and D'Ortenzio, R. and Heran, M.K.S.
DOI: 10.1002/pbc.29307
2021

NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling
Clinical Case Reports
Britton, H.M. and Levine, A.B. and Shen, Y. and Mungall, K. and Serrano, J. and Snuderl, M. and Pleasance, E. and Jones, S.J.M. and Laskin, J. and Marra, M.A. and Rassekh, S.R. and Deyell, R. and Yip, S. and Cheng, S. and Dunham, C.
DOI: 10.1002/ccr3.3804
2021

Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury
npj Precision Oncology
Williamson, L.M. and Rive, C.M. and Di Francesco, D. and Titmuss, E. and Chun, H.-J.E. and Brown, S.D. and Milne, K. and Pleasance, E. and Lee, A.F. and Yip, S. and Rosenbaum, D.G. and Hasselblatt, M. and Johann, P.D. and Kool, M. and Harvey, M. and Dix, D. and Renouf, D.J. and Holt, R.A. and Nelson, B.H. and Hirst, M. and Jones, S.J.M. and Laskin, J. and Rassekh, S.R. and Deyell, R.J. and Marra, M.A.
DOI: 10.1038/s41698-021-00238-4
2021

A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol
Canadian Journal of Kidney Health and Disease
Jain, A. and Huang, R. and Lee, J. and Jawa, N. and Lim, Y.J. and Guron, M. and Abish, S. and Boutros, P.C. and Brudno, M. and Carleton, B. and Cuvelier, G.D.E. and Gunaratnam, L. and Ho, C. and Adeli, K. and Kuruvilla, S. and Lajoie, G. and Liu, G. and Nathan, P.C. and Rod Rassekh, S. and Rieder, M. and Waikar, S.S. and Welch, S.A. and Weir, M.A. and Winquist, E. and Wishart, D.S. and Zorzi, A.P. and Blydt-Hansen, T. and Zappitelli, M. and Urquhart, B.
DOI: 10.1177/20543581211057708
2021

TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study
npj Precision Oncology
Meijer, A.J.M. and Diepstraten, F.A. and Langer, T. and Broer, L. and Domingo, I.K. and Clemens, E. and Uitterlinden, A.G. and de Vries, A.C.H. and van Grotel, M. and Vermeij, W.P. and Ozinga, R.A. and Binder, H. and Byrne, J. and van Dulmen-den Broeder, E. and Garrè, M.L. and Grabow, D. and Kaatsch, P. and Kaiser, M. and Kenborg, L. and Winther, J.F. and Rechnitzer, C. and Hasle, H. and Kepak, T. and Kepakova, K. and Tissing, W.J.E. and van der Kooi, A.L.F. and Kremer, L.C.M. and Kruseova, J. and Pluijm, S.M.F. and Kuehni, C.E. and van der Pal, H.J.H. and Parfitt, R. and Spix, C. and Tillmanns, A. and Deuster, D. and Matulat, P. and Calaminus, G. and Hoetink, A.E. and Elsner, S. and Gebauer, J. and Haupt, R. and Lackner, H. and Blattmann, C. and Neggers, S.J.C.M.M. and Rassekh, S.R. and Wright, G.E.B. and Brooks, B. and Nagtegaal, A.P. and Drögemöller, B.I. and Ross, C.J.D. and Bhavsar, A.P. and am Zehnhoff-Dinnesen, A.G. and Carleton, B.C. and Zolk, O. and van den Heuvel-Eibrink, M.M. and de Vries, A.C.H. and van Grotel, M. and van Dulmen-den Broeder, E. and van der Kooi, A.L.F. and Kremer, L.C.M. and van der Pal, H.J.H. and Calaminus, G.
DOI: 10.1038/s41698-021-00178-z
2021

Improving the regulation of medical cannabis in Canada to better serve pediatric patients,Améliorer la réglementation du cannabis médical au Canada pour mieux servir les patients pédiatriques
CMAJ
Huntsman, R.J. and Kelly, L.E. and Alcorn, J. and Appendino, J.P. and Bélanger, R.E. and Crooks, B. and Finkelstein, Y. and Gilpin, A. and Lewis, E. and Litalien, C. and Jacobs, J. and Moore-Hepburn, C. and Oberlander, T. and Rassekh, S.R. and Repetski, A.E. and Rieder, M.J. and Shackelford, A. and Siden, H. and Szafron, M. and T Jong, G.W. and Vaillancourt, R.
DOI: 10.1503/cmaj.202169-f
2021

Histologic Correlates of Molecular Group 4 Pediatric Medulloblastoma: A Retrospective Canadian Review
Pediatric and Developmental Pathology
Triscott, J. and Yip, S. and Johnston, D. and Michaud, J. and Rassekh, S.R. and Hukin, J. and Dunn, S. and Dunham, C.
DOI: 10.1177/10935266211001986
2021

Family attitudes about and experiences with medical cannabis in children with cancer or epilepsy: an exploratory qualitative study
CMAJ open
Gibbard, M. and Mount, D. and Rassekh, S.R. and Siden, H.H.
DOI: 10.9778/cmajo.20200212
2021

Malignant Mesothelioma With EWSR1-ATF1 Fusion in Two Adolescent Male Patients
Pediatric and Developmental Pathology
Ren, H. and Rassekh, S.R. and Lacson, A. and Lee, C.-H. and Dickson, B.C. and Chung, C.T. and Lee, A.F.
DOI: 10.1177/10935266211021222
2021

Prevalence and risk factors for cisplatin-induced hearing loss in children, adolescents, and young adults: a multi-institutional North American cohort study
The Lancet Child and Adolescent Health
Moke, D.J. and Luo, C. and Millstein, J. and Knight, K.R. and Rassekh, S.R. and Brooks, B. and Ross, C.J.D. and Wright, M. and Mena, V. and Rushing, T. and Esbenshade, A.J. and Carleton, B.C. and Orgel, E.
DOI: 10.1016/S2352-4642(21)00020-1
2021

Improving the regulation of medical cannabis in Canada to better serve pediatric patients
CMAJ
Huntsman, R.J. and Kelly, L.E. and Alcorn, J. and Appendino, J.P. and Bélanger, R.E. and Crooks, B. and Finkelstein, Y. and Gilpin, A. and Lewis, E. and Litalien, C. and Jacobs, J. and Moore-Hepburn, C. and Oberlander, T. and Rassekh, S.R. and Repetski, A.E. and Rieder, M.J. and Shackelford, A. and Siden, H. and Szafron, M. and T'Jong, G.W. and Vaillancourt, R.
DOI: 10.1503/cmaj.202169
2021

LGG-19. SPINAL LOW-GRADE GLIOMAS IN CANADIAN CHILDREN: A MULTI-CENTRE RETROSPECTIVE REVIEW
Neuro-oncology
Coltin H and Benipal S and Rassekh S and Nobre L and Bennett J and Tabori U and Wilson B and Mehta V and Beaudoin W and Zelcer S and Cheng S and Hukin J and Hawkins C and Bouffet E and Johnston D
12/2020

MBCL-24. CAN YOUNG CHILDREN WITH RELAPSED MEDULLOBLASTOMA BE SALVAGED AFTER INITIAL IRRADIATION-SPARING APPROACHES?
Neuro-oncology
Erker C and Larouche V and Margol A and Cacciotti C and Perreault S and Cohen K and AbdelBaki M and Hukin J and Rassekh S and Eisenstat D and Wilson B and Knipstein J and Hoppmann A and Lafay-Cousin L
12/2020

NFB-12. TRAMETINIB THERAPY FOR PEDIATRIC PATIENTS WITH REFRACTORY LOW GRADE GLIOMA OR EXTENSIVE SYMPTOMATIC PLEXIFORM NEUROFIBROMA
Neuro-oncology
Hounjet C and Ronsley R and Cheng S and Rassekh S and Duncan W and Dunham C and Gardiner J and Ghag A and P and Ludemann J and Wensley D and Rehmus W and Sargent M and Evans N and Popovska V and Hukin J
12/2020

High molecular weight adiponectin levels are inversely associated with adiposity in pediatric brain tumor survivors.
Scientific reports
Ronsley R and Rassekh SR and Fleming A and Empringham B and Jennings W and Portwine C and Burrow S and Zelcer S and Johnston DL and Thabane L and Samaan MC
DOI: 10.1038/s41598-020-75638-w
PubMed: 33122755
10/2020

42 - The Prevalence of Diabetes Mellitus in Childhood Cancer Survivors: A Systematic Review and Meta-Analysis
Canadian Journal of Diabetes
Sondra S. Chen and Ajantha Nadarajah and Kuan-Wen Wang and Stephanie Kay and Laura Banfield and Farid Foroutan and Donna Johnston and Shayna Zelcer and S. Rod Rassekh and Lehana Thabane and Adam J. Fleming and Carol Portwine and M. Constantine Samaan
DOI: 10.1016/j.jcjd.2020.08.048
10/2020

GSTM1 null variant associated with anthracycline-related cancer in pediatric cancer
Cancer
Shahrad Rod Rassekh
DOI: 10.1002/cncr.32945
09/2020

Evaluating the quantity, quality and size distribution of cell-free DNA by multiplex droplet digital PCR.
Scientific reports
Alcaide M and Cheung M and Hillman J and Rassekh SR and Deyell RJ and Batist G and Karsan A and Wyatt AW and Johnson N and Scott DW and Morin RD
DOI: 10.1038/s41598-020-69432-x
PubMed: 32724107
07/2020

Establishing a Framework for the Clinical Translation of Germline Findings in Precision Oncology.
JNCI cancer spectrum
Dixon K and Young S and Shen Y and Thibodeau ML and Fok A and Pleasance E and Zhao E and Jones M and Aubert G and Armstrong L and Virani A and Regier D and Gelmon K and Renouf D and Chia S and Schrader KA
DOI: 10.1093/jncics/pkaa045
PubMed: 33134827
05/2020

Epidemiologic Characteristics of Acute Kidney Injury During Cisplatin Infusions in Children Treated for Cancer.
JAMA network open
McMahon KR and Rassekh SR and Schultz KR and Blydt-Hansen T and Cuvelier GDE and Mammen C and Pinsk M and Carleton BC and Tsuyuki RT and Ross CJD and Palijan A and Huynh L and Applying Biomarkers to Minimize Long-term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group
DOI: 10.1001/jamanetworkopen.2020.3639
PubMed: 32383745
05/2020

Efficacy and safety of paediatric medicinal cannabis use: A scoping review
Paediatrics & Child Health
Colleen Pawliuk and Briana Chau and S Rod Rassekh and Terri McKellar and Harold (Hal) Siden
DOI: 10.1093/pch/pxaa031
04/2020

Circulating leptin levels are associated with adiposity in survivors of childhood brain tumors.
Scientific reports
Sims ED and Jennings WJ and Empringham B and Fleming A and Portwine C and Johnston DL and Zelcer SM and Rassekh SR and Burrow S and Thabane L and Samaan MC
DOI: 10.1038/s41598-020-61520-2
PubMed: 32170116
03/2020

Waning vaccine immunity and vaccination responses in children treated for acute lymphoblastic leukemia: A Canadian Immunization Research Network Study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Top KA and Vaudry W and Morris SK and Pham-Huy A and Pernica JM and Tapiéro B and Gantt S and Price VE and Rassekh SR and Sung L and McConnell A and Rubin E and Chawla R and Halperin SA
DOI: 10.1093/cid/ciaa163
PubMed: 32067048
02/2020

Vincristine-induced peripheral neurotoxicity: A prospective cohort.
Pediatric hematology and oncology
Nama N and Barker MK and Kwan C and Sabarre C and Solimano V and Rankin A and Raabe J and Ross CJ and Carleton B and Zwicker JG and Rassekh SR
DOI: 10.1080/08880018.2019.1677832
PubMed: 31682156
11/2019

Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer.
JAMA network open
Vaske OM and Bjork I and Salama SR and Beale H and Tayi Shah A and Sanders L and Pfeil J and Lam DL and Learned K and Durbin A and Kephart ET and Currie R and Newton Y and Swatloski T and Haussler D
DOI: 10.1001/jamanetworkopen.2019.13968
PubMed: 31651965
10/2019

Urgent need for "EBMM" in pediatric oncology: Evidence based medical marijuana.
Pediatric hematology and oncology
Rod Rassekh S
DOI: 10.1080/08880018.2019.1651805
PubMed: 31402734
08/2019

Third-generation cephalosporin-resistant urinary tract infections in children presenting to the paediatric emergency department.
Paediatrics & child health
Kang KT and Ng K and Kendrick J and Tilley P and Ting J and Rassekh S and Murthy S and Roberts A
DOI: 10.1093/pch/pxy175
PubMed: 32296278
02/2019

CYP2D6 as a treatment decision aid for ER-positive non-metastatic breast cancer patients: a systematic review with accompanying clinical practice guidelines
Breast Cancer Research and Treatment
Drögemöller, B.I. and Wright, G.E.B. and Shih, J. and Monzon, J.G. and Gelmon, K.A. and Ross, C.J.D. and Amstutz, U. and Carleton, B.C. and Chang, W.C. and Connolly, M.B. and Dionne, F. and Groeneweg, G. and Loucks, C.M. and MacLeod, S.M. and Pritchard, S. and Rassekh, S.R. and Sanatani, S. and Tanoshima, R. and Virani, S.A. and Monzon, J.G. and Bhavsar, A.P. and Rieder, M.J. and Shear, N.H. and Liu, G. and Khayat, P. and Bernstein, D. and Lesko, L.J. and Aminkeng, F.
DOI: 10.1007/s10549-018-5027-0
2019

Phase I study of vinblastine and temsirolimus in pediatric patients with recurrent or refractory solid tumors: Canadian Cancer Trials Group Study IND.218
Pediatric Blood and Cancer
Deyell, R.J. and Wu, B. and Rassekh, S.R. and Tu, D. and Samson, Y. and Fleming, A. and Bouffet, E. and Sun, X. and Powers, J. and Seymour, L. and Baruchel, S. and Morgenstern, D.A.
DOI: 10.1002/pbc.27540
2019

ALK-Positive Lung Adenocarcinoma Arising in an Adolescent Treated for Relapsed Neuroblastoma
Journal of Thoracic Oncology
Alwelaie, Y. and Deyell, R.J. and Nadel, H.R. and Tucker, T. and Laskin, J. and Rassekh, S.R. and Zhou, C. and English, J.C. and Lee, A.F.
DOI: 10.1016/j.jtho.2019.02.010
2019

Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes
Clinical Pharmacology and Therapeutics
Wright, G.E.B. and Amstutz, U. and Drögemöller, B.I. and Shih, J. and Rassekh, S.R. and Hayden, M.R. and Carleton, B.C. and Ross, C.J.D. and Visscher, H. and Aminkeng, F. and Higginson, M. and Massah, N. and Miao, F. and Bhavsar, A. and Lee, J. and Bendyshe-Walton, T. and Tanoshima, R. and Johnson, D. and Zhuwaki, C. and Honcharik, N. and Jong, G. and Israels, S. and Staub, M. and Rieder, M. and Faught, L. and Ito, S. and Nathan, P. and Karande, S. and Vaillancourt, R. and Johnston, D. and Nguyen, K. and Bussières, J.-F. and Lebel, D. and Jean-Louis, J.
DOI: 10.1002/cpt.1179
2019

Therapeutic implication of genomic landscape of adult metastatic sarcoma
JCO Precision Oncology
Feng, X. and Pleasance, E. and Zhao, E.Y. and Ng, T. and Grewal, J.K. and Mohammad, N. and Taylor, S.K. and Simmons, C. and Srikanthan, A. and Rod Rassekh, S. and Deyell, R. and Rauw, J. and Knowling, M. and Khoo, K. and Lee, U. and Noonan, K. and Hart, J. and Petter Tonseth, R. and Shen, Y. and Titmuss, E. and Jones, M. and Bonakdar, M. and Reisle, C. and Taylor, G.A. and Chan, S. and Mungall, K. and Chuah, E. and Zhao, Y. and Mungall, A. and Moore, R. and Lim, H. and Renouf, D.J. and Gelmon, K. and Yip, S. and Jones, S.J.M. and Marra, M. and Laskin, J.
DOI: 10.1200/PO.18.00325
2019

Pediatric oncology and stem cell transplant patients with healthcare-associated Clostridium difficile infection were already colonized on admission
Pediatric Blood and Cancer
Al-Rawahi, G.N. and Al-Najjar, A. and McDonald, R. and Deyell, R.J. and Golding, G.R. and Brant, R. and Tilley, P. and Thomas, E. and Rassekh, S.R. and O'Gorman, A. and Wong, P. and Turnham, L. and Dobson, S.
DOI: 10.1002/pbc.27604
2019

Pharmacogenomics of Cisplatin-Induced Ototoxicity: Successes, Shortcomings, and Future Avenues of Research
Clinical Pharmacology and Therapeutics
Drögemöller, B.I. and Wright, G.E.B. and Lo, C. and Le, T. and Brooks, B. and Bhavsar, A.P. and Rassekh, S.R. and Ross, C.J.D. and Carleton, B.C.
DOI: 10.1002/cpt.1483
2019

Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies.
JNCI cancer spectrum
Lorentzian A and Biegel JA and Ostrow DG and Rolf N and Liu CC and Rassekh SR and Deyell RJ and Triche T and Schultz KR and Rozmus J and Reid GSD and Lim CJ and Lange PF and Maxwell CA
DOI: 10.1093/jncics/pky079
PubMed: 30976750
10/2018

Comparative RNA-Sequencing Analysis Benefits a Pediatric Patient With Relapsed Cancer.
JCO precision oncology
Newton Y and Rassekh SR and Deyell RJ and Shen Y and Jones MR and Dunham C and Yip S and Leelakumari S and Zhu J and McColl D and Swatloski T and Salama SR and Ng T and Hendson G and Lee AF and Morozova O
04/2018

Birth weight and body mass index z-score in childhood brain tumors: A cross-sectional study
Scientific Reports
Wang, K.-W. and De Souza, R.J. and Fleming, A. and Johnston, D.L. and Zelcer, S.M. and Rassekh, S.R. and Burrow, S. and Thabane, L. and Samaan, M.C.
DOI: 10.1038/s41598-018-19924-8
2018

Clinical significance in pediatric oncology randomized controlled treatment trials: A systematic review
Trials
Howard, A.F. and Goddard, K. and Rassekh, S.R. and Samargandi, O.A. and Hasan, H.
DOI: 10.1186/s13063-018-2925-8
2018

Application of genomics to identify therapeutic targets in recurrent pediatric papillary thyroid carcinoma
Cold Spring Harbor Molecular Case Studies
Ronsley, R. and Rod Rassekh, S. and Shen, Y. and Lee, A.F. and Jantzen, C. and Halparin, J. and Albert, C. and Hawkins, D.S. and Amed, S. and Rothstein, R. and Mungall, A.J. and Dix, D. and Blair, G. and Nadel, H. and Jones, S.J.M. and Laskin, J. and Marra, M.A. and Deyell, R.J.
DOI: 10.1101/mcs.a002568
2018

Overweight, obesity and adiposity in survivors of childhood brain tumours: a systematic review and meta-analysis
Clinical obesity
Wang, K.-W. and Fleming, A. and Johnston, D.L. and Zelcer, S.M. and Rassekh, S.R. and Ladhani, S. and Socha, A. and Shinuda, J. and Jaber, S. and Burrow, S. and Singh, S.K. and Banfield, L. and de Souza, R.J. and Thabane, L. and Samaan, M.C.
DOI: 10.1111/cob.12224
2018

An initial health economic evaluation of pharmacogenomic testing in patients treated for childhood cancer with anthracyclines
Pediatric Blood and Cancer
Dionne, F. and Aminkeng, F. and Bhavsar, A.P. and Groeneweg, G. and Smith, A. and Visscher, H. and Rassekh, S.R. and Ross, C. and Carleton, B.
DOI: 10.1002/pbc.26887
2018

Reply to: Comment on: Comparison of hypersensitivity rates to intravenous and intramuscular PEG-asparaginase in children with acute lymphoblastic leukemia: A meta-analysis and systematic review
Pediatric Blood and Cancer
Hasan, H. and Shaikh, O.M. and Rassekh, S.R. and Howard, A.F. and Goddard, K.
DOI: 10.1002/pbc.27106
2018

High incidence of acute kidney injury during chemotherapy for childhood acute myeloid leukemia
Pediatric Blood and Cancer
Du Plessis, L. and Rassekh, S.R. and Mammen, C.
DOI: 10.1002/pbc.26915
2018

Tri-ponderal mass index in survivors of childhood brain tumors: A cross-sectional study
Scientific Reports
Sims, E.D. and Wang, K.-W. and Fleming, A. and Johnston, D.L. and Zelcer, S.M. and Rassekh, S.R. and Burrow, S. and Thabane, L. and Samaan, M.C.
DOI: 10.1038/s41598-018-34602-5
2018

Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.
Neurology
McCormack M and Gui H and Ingason A and Speed D and Wright GEB and Zhang EJ and Secolin R and Yasuda C and Kwok M and Wolking S and Becker F and Rau S and Avbersek A and Heggeli K and Leu C and Cavalleri GL
DOI: 10.1212/wnl.0000000000004853
PubMed: 29288229
12/2017

Pharmacogenomic screening for anthracycline-induced cardiotoxicity in childhood cancer
British Journal of Clinical Pharmacology
Aminkeng, F. and Ross, C.J.D. and Rassekh, S.R. and Rieder, M.J. and Bhavsar, A.P. and Sanatani, S. and Bernstein, D. and Hayden, M.R. and Amstutz, U. and Carleton, B.C.
DOI: 10.1111/bcp.13218
2017

Adiposity in childhood brain tumors: A report from the Canadian Study of determinants of endometabolic health in children (CanDECIDE Study)
Scientific Reports
Wang, K.-W. and De Souza, R.J. and Fleming, A. and Singh, S.K. and Johnston, D.L. and Zelcer, S.M. and Rassekh, S.R. and Burrow, S. and Scheinemann, K. and Thabane, L. and Samaan, M.C.
DOI: 10.1038/srep45078
2017

Targeted error-suppressed quantification of circulating tumor DNA using semi-degenerate barcoded adapters and biotinylated baits
Scientific Reports
Alcaide, M. and Yu, S. and Davidson, J. and Albuquerque, M. and Bushell, K. and Fornika, D. and Arthur, S. and Grande, B.M. and McNamara, S. and Tertre, M.C.D. and Batist, G. and Huntsman, D.G. and Cavallone, L. and Aguilar, A. and Basik, M. and Johnson, N.A. and Deyell, R.J. and Rassekh, S.R. and Morin, R.D.
DOI: 10.1038/s41598-017-10269-2
2017

Design and methods of the pan-canadian applying biomarkers to minimize long-term effects of childhood/adolescent cancer treatment (ABLE) nephrotoxicity study: A prospective observational cohort study
Canadian Journal of Kidney Health and Disease
McMahon, K.R. and Rassekh, S.R. and Schultz, K.R. and Pinsk, M. and Blydt-Hansen, T. and Mammen, C. and Tsuyuki, R.T. and Devarajan, P. and Cuvelier, G.D.E. and Mitchell, L.G. and Baruchel, S. and Palijan, A. and Carleton, B.C. and Ross, C.J.D. and Zappitelli, M.
DOI: 10.1177/2054358117690338
2017

Management of germline findings revealed throughout the course of tumor-normal whole genome sequencing in oncology.
Journal of Clinical Oncology
Lim, Howard John and Schrader, Kasmintan A. and Young, Sean and Nelson, Jessica and Fok, Alexandra and Pleasance, Erin and Jones, Martin and Shen, Yaoqing and Armstrong, Linlea and Virani, Alice and Rassekh, Shahrad Rod and Deyell, Rebecca and Yip, Stephen and Roscoe, Robyn and Karsan, Aly and Marra, Marco and Laskin, Janessa J.
DOI: 10.1200/JCO.2017.35.15_suppl.e13113
2017

Acute Kidney Injury During Chemotherapy for Acute Myeloid Leukemia
Pediatric Blood & Cancer
Du Plessis, Liezl and Mammen, Cherry and Potts, James and Rassekh, Shahrad
2017

The effectiveness of interventions to treat hypothalamic obesity in survivors of childhood brain tumours: a systematic review
Obesity Reviews
Wang, K.-W. and Chau, R. and Fleming, A. and Banfield, L. and Singh, S.K. and Johnston, D.L. and Zelcer, S.M. and Rassekh, S.R. and Burrow, S. and Valencia, M. and de Souza, R.J. and Thabane, L. and Samaan, M.C.
DOI: 10.1111/obr.12534
2017

Long-term Outcomes and Complications in Pediatric Ewing Sarcoma
American Journal of Clinical Oncology: Cancer Clinical Trials
Hamilton, S.N. and Carlson, R. and Hasan, H. and Rassekh, S.R. and Goddard, K.
DOI: 10.1097/COC.0000000000000176
2017

Comparison of hypersensitivity rates to intravenous and intramuscular PEG-asparaginase in children with acute lymphoblastic leukemia: A meta-analysis and systematic review
Pediatric Blood and Cancer
Hasan, H. and Shaikh, O.M. and Rassekh, S.R. and Howard, A.F. and Goddard, K.
DOI: 10.1002/pbc.26200
2017

MB-91OUTCOMES FOR YOUNG CHILDREN WITH BRAIN TUMOURS TREATED ACCORDING TO THE HEAD START PROTOCOLS: A SINGLE-CENTRE EXPERIENCE.
Neuro-oncology
Szpurko A and O'Halloran K and Potts J and Dunham C and Goddard K and Davis J and Strahlendorf C and Rassekh SR and Hukin J
DOI: 10.1093/neuonc/now076.87
05/2016

Early-onset liver failure with palpable abdominal mass in a neonate
NeoReviews
Sur, A. and Gilley, M. and Rassekh, S.R. and Osiovich, H.
DOI: 10.1542/neo.17-10-e624
2016

When Parents Refuse Potentially Curative Treatment for their Child's Cancer - Does Legal Intervention Improve Outcome?
Pediatric Blood & Cancer
Burns, C. and Rassekh, S. R. and Corbett, R. and MacFarlane, S. and Sullivan, M.
2016

Harnessing the power of big data to advance pediatric cancer care
Cancer Research
Morozova, Olena and Newton, Yulia and Cline, Melissa and Yip, Stephen and Rao, Arjun and Stuart, Josh and Goldstein, Ted and Salama, Sofie and Deyell, Rebecca and Rassekh, S. Rod and Haussler, David
2016

Pharmacogenomic Strategies for the Prevention of Anthracycline-Induced Heart Failure: Validation of a Genetic Association with a Non-Synonymous Variant in RARG
Pediatric Blood & Cancer
Bhavsar, A. P. and Rassekh, S. R. and Aminkeng, F. and Li, Y. and Gunaretnam, E. and Rieder, M. J. and Bernstein, D. and Hayden, M. R. and Carleton, B. C. and Ross, C. J. D.
2016

OUTCOMES FOR YOUNG CHILDREN WITH BRAIN TUMOURS TREATED ACCORDING TO THE HEAD START PROTOCOLS: A SINGLE-CENTRE EXPERIENCE
Neuro-Oncology
Szpurko, Ashley and O'Halloran, Katrina and Potts, Jim and Dunham, Christopher and Goddard, Karen and Davis, Jeffrey and Strahlendorf, Caron and Rassekh, Shahrad Rod and Hukin, Juliette
2016

Hypotension associated with ingestion of cannabinoids in two children with cancer
CMAJ
Li, A.M. and Rassekh, S.R.
DOI: 10.1503/cmaj.150847
2016

Clinical Practice Recommendations for the Management and Prevention of Cisplatin-Induced Hearing Loss Using Pharmacogenetic Markers
Therapeutic Drug Monitoring
Lee, J.W. and Pussegoda, K. and Rassekh, S.R. and Monzon, J.G. and Liu, G. and Hwang, S. and Bhavsar, A.P. and Pritchard, S. and Ross, C.J. and Amstutz, U. and Carleton, B.C. and Carleton, B.C. and Hayden, M.R. and Amstutz, U. and Hwang, S. and MacLeod, S. and Rassekh, R.S. and Smith, A. and Brunham, L. and Pritchard, S. and Aminkeng, F. and Shear, N.H. and Koren, G. and Ito, S. and Madadi, P. and Rieder, M.J. and Kim, R. and Maher, M. and Flockhart, D.
DOI: 10.1097/FTD.0000000000000298
2016

Clinical Implimentation of a Pharmacogenetic Risk Prediction Model for Cisplatin Ototoxicity and Anthracycline Cardiotoxicity
Pediatric Blood & Cancer
Rassekh, S. R. and Ross, C. J. D. and Groeneweg, G. and Bhavsar, A. P. and Aminkeng, F. and Bendyshe-Walton, T. and Miao, F. and Hill, M. and Massah, N. and Hildebrand, C. and Carleton, B. C.
2016

Genetic variants in SLC22A17 and SLC22A7 are associated with anthracycline-induced cardiotoxicity in children (vol 16, pg 1065, 2015)
Pharmacogenomics
Visser, Henk and Rassekh, S. Rod and Sandor, George S.
2016

Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity
British Journal of Clinical Pharmacology
Aminkeng, F. and Ross, C.J.D. and Rassekh, S.R. and Hwang, S. and Rieder, M.J. and Bhavsar, A.P. and Smith, A. and Sanatani, S. and Gelmon, K.A. and Bernstein, D. and Hayden, M.R. and Amstutz, U. and Carleton, B.C.
DOI: 10.1111/bcp.13008
2016

ETV6-NTRK3 is Expressed in a Subset of ALK-Negative Inflammatory Myofibroblastic Tumors
American Journal of Surgical Pathology
Alassiri, A.H. and Ali, R.H. and Shen, Y. and Lum, A. and Strahlendorf, C. and Deyell, R. and Rassekh, R. and Sorensen, P.H. and Laskin, J. and Marra, M. and Yip, S. and Lee, C.-H. and Ng, T.L.
DOI: 10.1097/PAS.0000000000000677
2016

Outcome of young children with high-grade glioma treated with irradiation-avoiding intensive chemotherapy regimens: Final report of the Head Start II and III trials
Pediatric Blood and Cancer
Espinoza, J.C. and Haley, K. and Patel, N. and Dhall, G. and Gardner, S. and Allen, J. and Torkildson, J. and Cornelius, A. and Rassekh, R. and Bedros, A. and Etzl, M. and Garvin, J. and Pradhan, K. and Corbett, R. and Sullivan, M. and McGowage, G. and Stein, D. and Jasty, R. and Sands, S.A. and Ji, L. and Sposto, R. and Finlay, J.L.
DOI: 10.1002/pbc.26118
2016

Lessons learned from the application of whole-genome analysis to the treatment of patients with advanced cancers.
Cold Spring Harbor molecular case studies
Laskin J and Jones S and Aparicio S and Chia S and Ch'ng C and Deyell R and Eirew P and Fok A and Gelmon K and Ho C and Huntsman D and Jones M and Kasaian K and Karsan A and Leelakumari S and Marra MA
DOI: 10.1101/mcs.a000570
PubMed: 27148575
10/2015

Characterizing standardized uptake values on diagnostic PET/CT scans according to pediatric lymphoma subtypes
Journal of Nuclear Medicine
Halparin, Jessica and Rassekh, Shahrad and Nadel, Helen
2015

Management of germline findings revealed throughout the course of tumor-normal whole genome sequencing in oncology
European Journal of Cancer
Lim, H. and Schrader, K. and Young, S. and Fok, A. and Pleasance, E. and Jones, M. and Shen, Y. and Armstrong, L. and Virani, A. and Rassekh, S. and Deyell, R. and Yip, S. and Roscoe, R. and Karsan, A. and Marra, M. and Laskin, J.
2015

A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer
Nature Genetics
Aminkeng, F. and Bhavsar, A.P. and Visscher, H. and Rassekh, S.R. and Li, Y. and Lee, J.W. and Brunham, L.R. and Caron, H.N. and Van Dalen, E.C. and Kremer, L.C. and Van Der Pal, H.J. and Amstutz, U. and Rieder, M.J. and Bernstein, D. and Carleton, B.C. and Hayden, M.R. and Ross, C.J.D.
DOI: 10.1038/ng.3374
2015

Whole genome analysis in a population-based cancer system: Results from sequencing > 100 metastatic cancer patients
European Journal of Cancer
Lim, H. and Renouf, D. and Sun, S. and Ho, C. and Gelmon, K. and Chia, S. and Pleasance, E. and Jones, M. and Shen, Y. and Eirew, P. and Rassekh, S. and Deyell, R. and Yip, S. and Huntsman, D. and Roscoe, R. and Fok, A. and Ma, Y. and Jones, S. and Marra, M. and Laskin, J.
2015

PEDIATRIC PERSONALIZED ONCOGENOMICS (PEDSPOG) - INITIAL OUTCOMES
Pediatric Blood & Cancer
Rassekh, Shahrad and Deyell, Rebecca and Shen, Yaoqing and Lee, Anna and Dunham, Chris and Virani, Alice and Armstrong, Linlea and Morin, Ryan and Yip, Stephen and Pleasance, Erin and Jones, Martin and Schein, Jacqueline and Mungall, Andrew and Zhao, Yongjun and Moore, Richard and Ma, Yussanne and Jones, Steven and Laskin, Janessa and Marra, Marco
2015

Evolution of a Pediatric Primary Cerebral ALK-1-Positive Anaplastic Large Cell Lymphoma on Serial MRI
Pediatric Neurosurgery
Dunbar, M.J. and Singhal, A. and Rassekh, S.R. and Dunham, C.
DOI: 10.1159/000380769
2015

Cisplatin Nephrotoxicity and Longitudinal Growth in Children with Solid Tumors
Medicine (United States)
Jiménez-Triana, C.A. and Castelán-Martínez, O.D. and Rivas-Ruiz, R. and Jiménez-Méndez, R. and Medina, A. and Clark, P. and Rassekh, R. and Castañeda-Hernández, G. and Carleton, B. and Medeiros, M.
DOI: 10.1097/MD.0000000000001413
2015

Clinical Practice Recommendations on Genetic Testing of CYP2C9 and VKORC1 Variants in Warfarin Therapy
Therapeutic Drug Monitoring
Shaw, K. and Amstutz, U. and Kim, R.B. and Lesko, L.J. and Turgeon, J. and Michaud, V. and Hwang, S. and Ito, S. and Ross, C. and Carleton, B.C. and Carleton, B. and Hayden, M.R. and Hosking, M. and Virani, S. and MacLeod, S. and Rassekh, R. and Smith, A. and Brunham, L. and Shear, N.H. and Koren, G. and Liu, G. and Rieder, M.J. and Kim, R. and Maher, M. and Flockhart, D. and Lesko, L. and Rhoades, J.
DOI: 10.1097/FTD.0000000000000192
2015

High-dose chemotherapy/stem cell transplantation (Hdsct)
Pediatric Neuro-oncology
DOI: 10.1007/978-1-4939-1541-5
2015

Genetic variants in SLC22A17 and SLC22A7 are associated with anthracycline-induced cardiotoxicity in children
Pharmacogenomics
Visscher, H. and Rassekh, S.R. and Sandor, G.S. and Caron, H.N. and Van Dalen, E.C. and Kremer, L.C. and Van Der Pal, H.J. and Rogers, P.C. and Rieder, M.J. and Carleton, B.C. and Hayden, M.R. and Ross, C.J.
DOI: 10.2217/pgs.15.61
2015

Diagnostic value of next-generation sequencing in an unusual sphenoid tumor
Oncologist
Jamshidi, F. and Pleasance, E. and Li, Y. and Shen, Y. and Kasaian, K. and Corbett, R. and Eirew, P. and Lum, A. and Pandoh, P. and Zhao, Y. and Schein, J.E. and Moore, R.A. and Rassekh, R. and Huntsman, D.G. and Knowling, M. and Lim, H. and Renouf, D.J. and Jones, S.J.M. and Marra, M.A. and Nielsen, T.O. and Laskin, J. and Yip, S.
DOI: 10.1634/theoncologist.2013-0390
2014

VKORC1 and CYP2C9 genotypes are predictors of warfarin-related outcomes in children
Pediatric Blood and Cancer
Shaw, K. and Amstutz, U. and Hildebrand, C. and Rassekh, S.R. and Hosking, M. and Neville, K. and Leeder, J.S. and Hayden, M.R. and Ross, C.J. and Carleton, B.C.
DOI: 10.1002/pbc.24932
2014

Vincristine and fine motor function of children with acute lymphoblastic leukemia
Canadian Journal of Occupational Therapy
Sabarre, C.L. and Rassekh, S.R. and Zwicker, J.G.
DOI: 10.1177/0008417414539926
2014

Growing teratoma syndrome in intracranial non-germinomatous germ cell tumors (iNGGCTs): A risk for secondary malignant transformation - A report of two cases
Child's Nervous System
Glass, T. and Cochrane, D.D. and Rassekh, S.R. and Goddard, K. and Hukin, J.
DOI: 10.1007/s00381-013-2295-1
2014

Intra-arterial methylprednisolone for severe steroid refractory gastrointestinal graft-versus-host disease
Pediatric Blood and Cancer
Bhuller, K.S. and Heran, M.K.S. and Wu, J.K.M. and Rassekh, S.R.
DOI: 10.1002/pbc.25155
2014

Guideline for primary antifungal prophylaxis for pediatric patients with cancer or hematopoietic stem cell transplant recipients
Pediatric Blood and Cancer
Science, M. and Robinson, P.D. and Macdonald, T. and Rassekh, S.R. and Dupuis, L.L. and Sung, L.
DOI: 10.1002/pbc.24847
2014

ASSESSING THE ACCURACY OF DEATH RECORDS AND PRE-MORTEM CLINICAL DIAGNOSES: A RETROSPECTIVE CHART REVIEW OF DECEASED CHILDREN DIAGNOSED WITH BRAIN TUMOURS IN BRITISH COLUMBIA, CANADA
Pediatric Blood & Cancer
Hasan, H. and Hendson, G. and Howard, F. and Rassekh, R. and Hukin, J. and Dunham, C. and Ahmed, T. and Lo, A. and Bradley, N. and Goddard, K.
2014

Role of TPMT and COMT genetic variation in cisplatin-induced ototoxicity
Clinical Pharmacology and Therapeutics
Carleton, B.C. and Ross, C.J. and Bhavsar, A.P. and Amstutz, U. and Pussegoda, K. and Visscher, H. and Lee, J.W. and Brooks, B. and Rassekh, S.R. and Dubé, M.-P. and Hayden, M.R.
DOI: 10.1038/clpt.2013.219
2014

Response to "Evaluation of Pharmacogenetic Markers to Predict the Risk of Cisplatin-Induced Ototoxicity"
Clinical Pharmacology and Therapeutics
Carleton, B.C. and Ross, C.J. and Bhavsar, A.P. and Lee, J.W. and Visscher, H. and Rassekh, S.R. and Hayden, M.R.
DOI: 10.1038/clpt.2014.90
2014

POLO-LIKE KINASE 1 (PLK1) ACTIVATES TRANSLATIONALLY CONTROLLED TUMOR PROTEIN (TCTP) PROMOTING THE DEVELOPMENT OF REFRACTORY MEDULLOBLASTOMA
Neuro-Oncology
Triscott, Joanna and Green, Marcus and Foster, Colleen and Fotovati, Abbas and Berns, Rachel and O'Halloran, Katrina and Singhal, Ash and Hukin, Juliette and Rassekh, S. Rod and Yip, Stephen and Toyota, Brian and Dunham, Christopher and Dunn, Sandra E.
2014

Genetic markers of cisplatin-induced hearing loss in children
Clinical Pharmacology and Therapeutics
Carleton, B.C. and Ross, C.J. and Pussegoda, K. and Bhavsar, A.P. and Visscher, H. and Lee, J.W. and Brooks, B. and Rassekh, S.R. and Dubé, M.-P.P. and Hayden, M.R.
DOI: 10.1038/clpt.2014.92
2014

RISK AND PATTERNS OF UTILIZATION OF COMMUNITY CARE AND MENTAL HEALTH SERVICES AMONG CHILDHOOD, ADOLESCENT AND YOUNG ADULT CANCER SURVIVORS IN BRITISH COLUMBIA, CANADA
Pediatric Blood & Cancer
McBride, M. and Li, D. and Goddard, K. and Pritchard, S. and Rassekh, S. R. and Sheps, S.
2014

Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent
Pharmacogenomics Journal
Aminkeng, F. and Ross, C.J.D. and Rassekh, S.R. and Brunham, L.R. and Sistonen, J. and Dube, M.-P. and Ibrahim, M. and Nyambo, T.B. and Omar, S.A. and Froment, A. and Bodo, J.-M. and Tishkoff, S. and Carleton, B.C. and Hayden, M.R.
DOI: 10.1038/tpj.2013.13
2014

Clinical practice guideline: CYP2D6 genotyping for safe and efficacious codeine therapy.
Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique
Madadi P and Amstutz U and Rieder M and Ito S and Fung V and Hwang S and Turgeon J and Michaud V and Koren G and Carleton BC and CPNDS Clinical Recommendations Group
PubMed: 24214521
11/2013

Comparative genomic hybridization of Wilms' tumor
Methods in Molecular Biology
Rassekh, S.R. and Rajcan-Separovic, E.
DOI: 10.1007/978-1-62703-281-0_16
2013

Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children
Cancer Research
Triscott, J. and Lee, C. and Foster, C. and Manoranjan, B. and Pambid, M.R. and Berns, R. and Fotovati, A. and Venugopal, C. and O'Halloran, K. and Narendran, A. and Hawkins, C. and Ramaswamy, V. and Bouffet, E. and Taylor, M.D. and Singhal, A. and Hukin, J. and Rassekh, R. and Yip, S. and Northcott, P. and Singh, S.K. and Dunham, C. and Dunn, S.E.
DOI: 10.1158/0008-5472.CAN-12-4331
2013

PHARMACOGENOMICS OF VINCRISTINE-INDUCED NEUROTOXICITY IN PEDIATRIC CANCER PATIENTS
Pediatric Blood & Cancer
Rassekh, S. and Amstutz, U. and Loo, T. and Gylling, H. and Zada, Y. Feroz and Dube, M. and Hukin, J. and Hayden, M. and Ross, C. and Carleton, B.
2013

Pharmacogenetics of warfarin safety and effectiveness in children
Faseb Journal
Shaw, Kaitlyn and Amstutz, Ursula and Hildebrand, Claudette and Rassekh, S. Rod and Dube, Marie-Pierre and Hayden, Michael R. and Ross, Colin J. and Carleton, Bruce C.
2013

PERSONALIZING THE TREATMENT FOR MEDULLOBLASTOMA: POLO-LIKE KINASE 1 (PLK1) AS A MOLECULAR TARGET FOR THE SONIC HEDGEHOG (SHH) SUBTYPE
Neuro-Oncology
Lee, Cathy and Triscott, Joanna and Foster, Colleen and Manoranjan, Branavan and Pambid, Mary Rose and Fotovati, Abbas and Berns, Rachel and Venugopal, Chitra and O'Halloran, Katherine and Narendran, Aru and Northcott, Paul and Taylor, Michael D. and Singh, Sheila K. and Singhal, Ash and Rassekh, Rod and Maxwell, Christopher A. and Dunham, Christopher and Dunn, Sandra E.
2013

Erratum: Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy (Nature Genetics (2009) 41 (1345-1349))
Nature Genetics
Ross, C.J.D. and Katzov-Eckert, H. and Dubé, M.-P. and Brooks, B. and Rassekh, S.R. and Barhdadi, A. and Feroz-Zada, Y. and Visscher, H. and Brown, A.M.K. and Rieder, M.J. and Rogers, P.C. and Phillips, M.S. and Carleton, B.C. and Hayden, M.R.
DOI: 10.1038/ng.0513-578
2013

Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children
Clinical Pharmacology and Therapeutics
Pussegoda, K. and Ross, C.J. and Visscher, H. and Yazdanpanah, M. and Brooks, B. and Rassekh, S.R. and Zada, Y.F. and Dubé, M.-P. and Carleton, B.C. and Hayden, M.R.
DOI: 10.1038/clpt.2013.80
2013

Cancer Pharmacogenomics in Children
Cancer Genomics: From Bench to Personalized Medicine
DOI: 10.1016/B978-0-12-396967-5.00006-2
2013

Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children
Pediatric Blood and Cancer
Visscher, H. and Ross, C.J.D. and Rassekh, S.R. and Sandor, G.S.S. and Caron, H.N. and van Dalen, E.C. and Kremer, L.C. and van der Pal, H.J. and Rogers, P.C. and Rieder, M.J. and Carleton, B.C. and Hayden, M.R.
DOI: 10.1002/pbc.24505
2013

Outcome of infants and young children with newly diagnosed ependymoma treated on the "head Start" III prospective clinical trial
Journal of Neuro-Oncology
Venkatramani, R. and Ji, L. and Lasky, J. and Haley, K. and Judkins, A. and Zhou, S. and Sposto, R. and Olshefski, R. and Garvin, J. and Tekautz, T. and Kennedy, G. and Rassekh, S.R. and Moore, T. and Gardner, S. and Allen, J. and Shore, R. and Moertel, C. and Atlas, M. and Dhall, G. and Finlay, J.
DOI: 10.1007/s11060-013-1111-9
2013

Cancer pharmacogenomics in children: Research initiatives and progress to date
Pediatric Drugs
Rassekh, S.R. and Ross, C.J.D. and Carleton, B.C. and Hayden, M.R.
DOI: 10.1007/s40272-013-0021-9
2013

Antidepressant use among survivors of childhood, adolescent and young adult cancer: A report of the childhood, adolescent and young adult cancer survivor (CAYACS) research program
Pediatric Blood and Cancer
Deyell, R.J. and Lorenzi, M. and Ma, S. and Rassekh, S.R. and Collet, J.-P. and Spinelli, J.J. and Mcbride, M.L.
DOI: 10.1002/pbc.24446
2013

Prenatal presentation of fronto-orbital congenital infantile fibrosarcoma: A clinicopathologic report
JAMA Ophthalmology
Tsang, H.H. and Dolman, P.J. and Courtemanche, D.J. and Rassekh, S.R. and Senger, C. and Lyons, C.J.
DOI: 10.1001/jamaophthalmol.2013.1934
2013

Clinical practice guideline: CYP2D6 genotyping for safe and efficacious codeine therapy
Journal of Population Therapeutics and Clinical Pharmacology
Madadi, P. and Amstutz, U. and Rieder, M. and Ito, S. and Fung, V. and Hwang, S. and Turgeon, J. and Michaud, V. and Koren, G. and Carleton, B.C. and Hayden, M.R. and Ross, C.J. and MacLeod, S. and Rassekh, R. and Lauder, G. and Smith, A. and Brunham, L. and Shear, N.H. and Liu, G. and Kim, R. and Maher, M. and Flockhart, D.
2013

THE Y-BOX BINDING PROTEIN-1 CONVEYS TEMOZOLOMIDE RESISTANCE BY THE INHIBITING DNA DAMAGE RESPONSE PATHWAY THROUGH THE POLYCOMB REPRESSOR BMI-1
Neuro-Oncology
Fotovati, Abbas and Radiloff, Daniel and Coute, Nicole and Triscott, Joanna and Chen, James and Yip, Stephen and Louis, David and Toyota, Brian and Hukin, Juliette and Rassekh, S. Rod and Singhal, Ash and Dunham, Chris and Dunn, Sandra
2013

Predicting Anthracycline-induced Cardiotoxicity in Children - Genome-Wide Association Study
Faseb Journal
Aminkeng, Folefac and Ross, Colin J. D. and Rassekh, Rod S. and Brunham, Liam R. and Weissman, Cory and Dube, Marie-Pierre and Visscher, Henk and Rieder, Michael J. and Carleton, Bruce C. and Hayden, Michael R.
2013

Successful treatment of acute lymphoblastic leukemia in a child with trisomy 21 and complex congenital heart disease with mechanical prosthetic valve.
Case reports in pediatrics
Alvi S and Shereck E and Heran MK and Sandor GG and Rassekh SR
DOI: 10.1155/2012/193093
PubMed: 23082266
10/2012

OUTCOMES OF CHILDREN TREATED WITH A CHEMOTHERAPY-ONLY INFANT PROTOCOL AT BRITISH COLUMBIA'S CHILDREN'S HOSPITAL
Neuro-Oncology
O'Halloran, Katrina and Hukin, Juliette and Singhal, Ash and Dunham, Chris and Goddard, Karen and Rassekh, Shahrad R.
2012

Pharmacogenetics of Warfarin in Children
Pharmacoepidemiology and Drug Safety
Shaw, Kaitlyn and Amstutz, Ursula and Hildebrand, Claudette and Rassekh, S. Rod and Ross, Colin J. and Hayden, Michael R. and Carleton, Bruce C.
2012

CHARACTERISTICS OF HIGH HEALTH CARE USERS AMONG CHILDHOOD, ADOLESCENT AND YOUNG ADULT CANCER SURVIVORS IN BRITISH COLUMBIA, CANADA
Pediatric Blood & Cancer
Rogers, Paul and Lorenzi, Maria and Tsonis, Miranda and Goddard, Karen and Pritchard, Sheila and Rassekh, Shahrad Rod and Sheps, Sam and McBride, Mary L.
2012

Atypical teratoid rhabdoid tumors (ATRTs): The British Columbia's Children's Hospital's experience, 1986-2006
Brain Pathology
Fleming, A.J. and Hukin, J. and Rassekh, R. and Fryer, C. and Kim, J. and Stemmer-Rachamimov, A. and Birks, D.K. and Huang, A. and Yip, S. and Dunham, C.
DOI: 10.1111/j.1750-3639.2011.00561.x
2012

Possible differentiation of cerebral glioblastoma into pleomorphic xanthoastrocytoma: An unusual case in an infant - Case report
Journal of Neurosurgery: Pediatrics
Yang, M.M.H. and Singhal, A. and Rassekh, S.R. and Yip, S. and Eydoux, P. and Dunham, C.
DOI: 10.3171/2012.1.PEDS11326
2012

Platinum-induced ototoxicity in children: A consensus review on mechanisms, predisposition, and protection, including a new International Society of Pediatric Oncology Boston ototoxicity scale
Journal of Clinical Oncology
Brock, P.R. and Knight, K.R. and Freyer, D.R. and Campbell, K.C.M. and Steyger, P.S. and Blakley, B.W. and Rassekh, S.R. and Chang, K.W. and Fligor, B.J. and Rajput, K. and Sullivan, M. and Neuwelt, E.A.
DOI: 10.1200/JCO.2011.39.1110
2012

MALIGNANT TRANSFORMATION OF GROWING TERATOMAS: A GROWING PHENOMENON
Neuro-Oncology
Glass, Torin and Cochrane, D. Douglas and Rassekh, Shahrad Rod and Goddard, Karen and Hukin, Juliette
2012

GENETIC PREDISPOSITION TO ADVERSE EVENTS
Pediatric Blood & Cancer
Rassekh, Shahrad Rod
2012

Erratum: Economic impact of a genetic test for cisplatin-induced ototoxicity (The Pharmacogenomics Journal (2012) 12 (205-213) DOI: 10.1038/tpj.2011.15)
Pharmacogenomics Journal
Dionne, F. and Mitton, C. and Rassekh, R. and Brooks, B. and Ross, C. and Hayden, M. and Carleton, B.
DOI: 10.1038/tpj.2011.21
2012

Economic impact of a genetic test for cisplatin-induced ototoxicity
Pharmacogenomics Journal
Dionne, F. and Mitton, C. and Rassekh, R. and Brooks, B. and Ross, C. and Hayden, M. and Carleton, B.
DOI: 10.1038/tpj.2011.15
2012

Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children
Journal of Clinical Oncology
Visscher, H. and Ross, C.J.D. and Rassekh, S.R. and Barhdadi, A. and Dubé, M.-P. and Al-Saloos, H. and Sandor, G.S. and Caron, H.N. and Van Dalen, E.C. and Kremer, L.C. and Van Der Pal, H.J. and Brown, A.M.K. and Rogers, P.C. and Phillips, M.S. and Rieder, M.J. and Carleton, B.C. and Hayden, M.R.
DOI: 10.1200/JCO.2010.34.3467
2012

Pharmacogenomics of serious adverse drug reactions in pediatric oncology.
Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique
Ross CJ and Visscher H and Rassekh SR and Castro-Pastrana LI and Shereck E and Carleton B and Hayden MR
PubMed: 21467604
03/2011

Nephrotic syndrome developing during induction chemotherapy for childhood acute lymphoblastic leukemia
Clinical and Experimental Nephrology
Prestidge, C. and Rassekh, S.R. and Matsell, D.G.
DOI: 10.1007/s10157-010-0401-1
2011

LATE MORBIDITY AS MEASURED BY HOSPITAL ADMISSIONS AMONG SURVIVORS OF CHILDHOOD WILMS TUMORS
Pediatric Blood & Cancer
Goddard, Karen and Mcbride, Mary and Lorenzi, Maria and Rassekh, Rod
2011

HIGH INCIDENCE OF FUNGAL INFECTIONS IN PEDIATRIC ONCOLOGY PATIENTS IN BRITISH COLUMBIA
Pediatric Blood & Cancer
Rassekh, Shahrad Rod and Ratzlafl, Matthew and Al-Dahhagh, Mona and Lloyd, Claire and Damphousse, Amelie and Jamieson, Douglas and AI-Rawahi, Ghada and Kaman, Tobias R.
2011

Outcome of Head Start III multinational protocol for newly diagnosed central nervous system (CNS) primitive neuroectodermal tumors (pnet) of young children.
Journal of Clinical Oncology
Davidson, T. B. and Ji, L. and Haley, K. and Dhall, G. and Grimm, J. P. and Gilles, F. H. and Gardner, S. L. and Allen, J. C. and Bedros, A. A. and Etzl, M. M. and Olshefski, R. S. and Cornelius, A. and Torkildson, J. and Kennedy, G. A. and Fangusaro, J. R. and Rassekh, S. R. and Joyce, M. J. and Bertolone, S. J. and Sposto, R. and Finlay, J. L.
2011

FINAL REPORT ON OUTCOME OF CHILDREN WITH NEWLY DIAGNOSED HIGH-GRADE GLIOMA (HGG) TREATED WITH MULTI-DRUG INDUCTION CHEMOTHERAPY FOLLOWED BY CONSOLIDATIVE MYELOABLATIVE CHEMOTHERAPY AND AUTOLOGOUS HEMATOPOIETIC PROGENITOR CELL RESCUE (AuHPCR) ON THE "HEAD START" II AND III PROTOCOLS
Neuro-Oncology
Espinoza, Juan and Haley, Kelley and Patel, Neha and Dhall, Girish and Gardner, Sharon and Jeffrey, Allen and Torkildson, Joseph and Cornelius, Albert and Rassekh, Rod and Bedros, Antranik and Etzl, Morris and Garvin, James and Pradhan, Kamnesh and Corbett, Robin and Sullivan, Michael and McGowage, Geoffrey and Puccetti, Diane and Stein, Dagmar and Jasty, Rama and Ji, Lingyun and Sposto, Richard and Finlay, Jonathan L.
2011

Pharmacogenomics of serious adverse drug reactions in pediatric oncology
Journal of Population Therapeutics and Clinical Pharmacology
Ross, C.J.D. and Visscher, H. and Rod Rassekh, S. and Castro-Pastrana, L.I. and Shereck, E. and Carleton, B. and Hayden, M.R.
2011

Pathology, genetics and cytogenetics of Wilms' tumour
Pathology
Md Zin, R. and Murch, A. and Charles, A.
DOI: 10.1097/PAT.0b013e3283463575
2011

Severe genital ulceration in an acute epstein-barr virus infection
Pediatric Infectious Disease Journal
Al-Rawahi, G.N. and Dobson, S.R. and Scheifele, D.W. and Rassekh, S.R. and Murphy, J.J.
DOI: 10.1097/INF.0b013e3181f41b2e
2011

OUTCOME OF INFANTS AND YOUNG CHILDREN WITH NEWLY DIAGNOSED EPENDYMOMA TREATED ON "HEAD START" III PROTOCOL
Neuro-Oncology
Venkatramani, Rajkumar and Haley, Kelley and Gilles, Floyd and Sposto, Richard and Ji, Lingyun and Olshefski, Randal and Garvin, James and Tekautz, Tanya and Kennedy, Gloria and Rassekh, Rod and Moore, Theodore and Gardner, Sharon and Allen, Jeffrey and Shore, Richard and Moertel, Chris and Atlas, Mark and Lasky, Joseph and Finlay, Jonathan
2011

The Canadian Pharmacogenomics Network for Drug Safety: a model for safety pharmacology.
Thyroid : official journal of the American Thyroid Association
Ross CJ and Visscher H and Sistonen J and Brunham LR and Pussegoda K and Loo TT and Rieder MJ and Koren G and Carleton BC and Hayden MR and CPNDS Consortium
DOI: 10.1089/thy.2010.1642
PubMed: 20578893
07/2010

PROGNOSTIC FACTORS INFLUENCING SURVIVAL FOR CNS ATYPICAL TERATOID RHABDOID TUMORS IN BRITISH COLUMBIA
Pediatric Blood & Cancer
Fleming, Adam and Hukin, Juliette and Rassekh, S. Rod and Fryer, Chris and Yip, Stephen and Dunham, Christopher
2010

OTOTOXICITY AS A PREDICTOR OF OUTCOME IN PATIENTS WITH OSTEOSARCOMA TREATED WITH CISPLATIN
Pediatric Blood & Cancer
Rassekh, SR and Dedhar, A and Brooks, B and Senger, C and McCaffrey, L and Brown, K and Kozak, F
2010

Reclassification of ICD-9 codes into meaningful categories for oncology survivorship research
Journal of Cancer Epidemiology
Rassekh, S.R. and Lorenzi, M. and Lee, L. and Devji, S. and McBride, M. and Goddard, K.
DOI: 10.1155/2010/569517
2010

CASE-BASED INTERACTIVE E-LEARNING PROGRAMS FOR PEDIATRIC ONCOLOGY: RATIONALE, DEVELOPMENT AND USER EVALUATION RESULTS
Pediatric Blood & Cancer
Goddard, Karen and Brown, Tanya and Hukin, Juliette and DeZorzi, Pia and Johnston, Donna and Punnett, Angela and Rassekh, Shawn and Shaikh, Furqan and Olson, Rob
2010

Abnormal liver transaminases and conjugated hyperbilirubinemia at presentation of acute lymphoblastic leukemia
Pediatric Blood and Cancer
Segal, I. and Rassekh, S.R. and Bond, M.C. and Senger, C. and Schreiber, R.A.
DOI: 10.1002/pbc.22549
2010

RESECTION ALONE IN LIEU OF ADJUVANT THERAPY IN THE TREATMENT OF MEDULLOBLASTOMA IN GORLIN SYNDROME
Neuro-Oncology
Rasmussen, L and Hukin, J and Rassekh, SR and Singhal, A and Hendson, G
2010

REDEFINING THE INCIDENCE AND OUTCOMES OF CNS ATYPICAL TERATOID RHABDOID TUMOURS AT BC CHILDREN'S HOSPITAL
Pediatric Blood & Cancer
Fleming, A and Hukin, J and Rassekh, SR and Fryer, C and Dunham, C
2010

OTOTOXICITY AS A PREDICTOR OF OUTCOME IN OSTEOSARCOMA PATIENTS TREATED WITH CISPLATIN
Journal of Investigative Medicine
Dedhar, A. and Brooks, B. and Senger, C. and Kozac, F. and Rassekh, R.
2010

LACK OF CISPLATIN INDUCED HEARING LOSS AS A PREDICTOR OF A POOR OUTCOME IN CHILDREN WITH OSTEOSARCOMA
Pediatric Blood & Cancer
Rassekh, Shahrad Rod and Dedhar, Alysha and Brooks, Beth and Senger, Christof and MCCaffrey, Lindsay and Brown, Kenneth and Carleton, Bruce and Hayden, Michael and Kozak, Frederick
2010

HEALTH CARE PROVIDERS' VIEWS OF INFORMED CONSENT AND JOINT DECISION MAKING IN PEDIATRIC PATIENTS WITH BRAIN TUMOURS
Pediatric Blood & Cancer
Olson, Robert and Hukin, Juliette and Steenburgh, Suzanne and Rassekh, Rod and Ho, Anita and Bobinski, Mary Anne and Goddard, Karen
2010

Childhood, adolescent, and young adult cancer survivors research program of British Columbia: Objectives, study design, and cohort characteristics
Pediatric Blood and Cancer
McBride, M.L. and Rogers, P.C. and Sheps, S.B. and Glickman, V. and Broemeling, A.-M. and Goddard, K. and Hu, J. and Lorenzi, M. and Peacock, S. and Pritchard, S. and Rassekh, S.R. and Siegel, L. and Spinelli, J.J. and Teckle, P. and Xie, L.
DOI: 10.1002/pbc.22476
2010

REDEFINING THE INCIDENCE, OUTCOMES, AND PROGNOSTIC FACTORS FOR CNS ATYPICAL TERATOID RHABDOID TUMOURS AT BC CHILDREN'S HOSPITAL
Neuro-Oncology
Fleming, AJ and Hukin, J and Rassekh, SR and Fryer, CJH and Yip, S and Dunham, C
2010

Inflammatory myofibroblastic tumour of the subglottis in a 5-year-old.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
Hartl T and Moxham JP and Ludemann JP and Rassekh SR
PubMed: 19476756
06/2009

In Vitro Inferiority of Ceftazidime Compared With Other beta-lactams for Viridans Group Streptococcus Bacteremia in Pediatric Oncology Patients Implications for Antibiotic Choices
Journal of Pediatric Hematology Oncology
Paulus, S and Dobson, S and Rassekh, S and Hill, EB
2009

Inflammatory myofibroblastic tumour of the subglottis in a 5-year-old
Journal of Otolaryngology - Head and Neck Surgery
Hartl, T. and Moxham, J.P. and Ludemann, J.P. and Rassekh, S.R.
DOI: 10.2310/7070.2009.080211
2009

In vitro inferiority of ceftazidime compared with other ß-lactams for viridans group streptococcus bacteremia in pediatric oncology patients: Implications for antibiotic choices
Journal of Pediatric Hematology/Oncology
Paulus, S. and Dobson, S. and Rassekh, S. and Blondel-Hill, E.
DOI: 10.1097/MPH.0b013e31819a5d40
2009

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy
Nature Genetics
Ross, C.J.D. and Katzov-Eckert, H. and Dubé, M.-P. and Brooks, B. and Rassekh, S.R. and Barhdadi, A. and Feroz-Zada, Y. and Visscher, H. and Brown, A.M.K. and Rieder, M.J. and Rogers, P.C. and Phillips, M.S. and Carleton, B.C. and Hayden, M.R.
DOI: 10.1038/ng.478
2009

IDENTIFICATION OF GENETIC MARKERS OF SEVERE HEARING LOSS IN CHILDREN RECEIVING CISPLATIN
Pediatric Blood & Cancer
Rassekh, Rod and Ross, Colin and Brooks, Beth and Katzov, Hagit and Dube, Marie-Pierre and Carleton, Bruce and Hayden, Michael and Rogers, Paul
2009

Late hospitalizations among survivors of pediatric brain tumors
Neuro-Oncology
Rassekh, SR and Goddard, K and Lorenzi, M and Xie, LJ and Page, J and Lee, L and Mcbride, M
2008

Screening for submicroscopic chromosomal rearrangements in Wilms tumor using whole-genome microarrays
Cancer Genetics and Cytogenetics
Rassekh, S.R. and Chan, S. and Harvard, C. and Dix, D. and Qiao, Y. and Rajcan-Separovic, E.
DOI: 10.1016/j.cancergencyto.2007.12.015
2008

Canadian national active surveillance network for adverse drug reactions: Genotypic approaches to therapy in children (GATC): The first year
Pharmacoepidemiology and Drug Safety
Carleton, B. C. and Warn, D. and Stenton, S. and Rassekh, R. and Smith, M. A. and Dhami, B. and Ross, C. and Hayden, M. R.
2007

Genotypic approaches to therapy in children: A national active surveillance network (GATC) to study the pharmacogenomics of severe adverse drug reactions in children
Annals of the New York Academy of Sciences
DOI: 10.1196/annals.1423.020
2007

A roadmap for engaging first nations communities in medical research.
Journal of Investigative Medicine
Rassekh, R and Miller, K and Louie, P and Benton, D and Macnab, A
2004

Adults with myelomeningocele: Functional outcome of the last 5 years of graduates from a children's hospital
Journal of Investigative Medicine
Rassekh, SR and Thiessen, PN and Irwin, BJ and Chambers, K
2003

Validity and reliability of a pediatric pneumonia score
Journal of Investigative Medicine
Hirsh, D and Rassekh, R and Appelt, G and Macnab, A
2003

Promoting healthy food choices among children in first nations communities.
Journal of Investigative Medicine
Louie, P and Tandan, T and Rassekh, R and Clarke, M and Duffy, D and Macnab, A
2003

Functional deterioration following placode untethering in myelomeningocele
Pediatric Neurosurgery
Cochrane, D.D. and Rassekh, S.R. and Thiessen, P.N.
DOI: 10.1159/000028621
1998

Research

Genotype-Specific Approaches to Therapy in Children with Cancer (GATC Cancer Study)
Adverse events due to medications are a common complication of the treatment of childhood cancer. This study is attempting to identify genetic risk factors that may be associated with adverse drug events. We have designed a case-control study to investigate all adverse events, with an initial focus on anthracycline-induced cardiomyopathy and cisplatin induced hearing loss.
Through a partnership with Drs Michael Hayden and Bruce Carleton, and a 2 year grant from the C17 Research Network, we have made this study available to 17 hospitals.

Grants

Michael Cuccione Childhood Cancer Research Program Brain Tumour Grant, start up funding - Project

“Outcomes in brain tumors treated with a chemotherapy only approach”

Honours & Awards

Outstanding Junior Resident (July 2001)

Outstanding Resident Researcher Award (June 2002)

Research Group Members

Justin Yap