Overview

I am a developmental pediatrician studying how early social experience (prenatal maternal mental illness and psychotropic medication exposure) influences the developmental origins of stress and self-regulation and its impact on thinking, learning and behaviour during childhood.

Publications

Examining the interaction between prenatal stress and polygenic risk for attention-deficit/hyperactivity disorder on brain growth in childhood: Findings from the DREAM BIG consortium
Developmental Psychobiology
Mónica López-Vicente and Eszter Szekely and Marie-Elyse Lafaille-Magnan and J. Bruce Morton and Tim F. Oberlander and Celia M. T. Greenwood and Ryan L. Muetzel and Henning Tiemeier and Anqi Qiu and Ashley Wazana and Tonya White
DOI: 10.1002/dev.22481
05/2024

Prenatal serotonin reuptake inhibitor antidepressant exposure, SLC6A4 genetic variations, and cortisol activity in 6-year-old children of depressed mothers: A cohort study
Developmental Psychobiology
Enav Z. Zusman and Cecil M. Y. Chau and Jeffrey N. Bone and Kaia Hookenson and Ursula Brain and Melissa B. Glier and Ruth E. Grunau and Joanne Weinberg and Angela M. Devlin and Tim F. Oberlander
DOI: 10.1002/dev.22425
11/2023

Placebo effects in children with autism spectrum disorder
Developmental Medicine & Child Neurology
Aurore Curie and Tim F. Oberlander and Karin B. Jensen
DOI: 10.1111/dmcn.15574
10/2023

The Role of Parenting Stress as a Mediator in the Relationship Between Postpartum Depressive Symptoms and Early Childhood Internalizing Behaviour
Child Psychiatry & Human Development
Dianne Semeniuk and Katelynn E. Boerner and Ursula Brain and Deirdre Ryan and Tim F. Oberlander
DOI: 10.1007/s10578-023-01596-9
09/2023

Conditioning induced placebo-like and nocebo-like effects of thermal discomfort in adults but not in youth
British Journal of Pain
Ella Weik and Regula Neuenschwander and Brinn Edgington and Karin Jensen and Christine M Tipper and Tim F Oberlander
DOI: 10.1177/20494637231153364
08/2023

“Making Data the Drug”: A Pragmatic Pilot Feasibility Randomized Crossover Trial of Data Visualization as an Intervention for Pediatric Chronic Pain
Children
Katelynn Boerner and Unma Desai and Jessica Luu and Karon E. MacLean and Tamara Munzner and Haley Foladare and Jane Shen and Javed Gill and Tim F. Oberlander
DOI: 10.3390/children10081355
08/2023

Family Perspectives on In-Home Multimodal Longitudinal Data Collection for Children Who Function Across the Developmental Spectrum
Journal of Developmental & Behavioral Pediatrics
Katelynn E. Boerner and Leora Pearl-Dowler and Liisa Holsti and Marie-Noelle Wharton and Harold Siden and Tim F. Oberlander
DOI: 10.1097/DBP.0000000000001183
05/2023

Associations between maternal depressive symptoms and selective serotonin reuptake inhibitor antidepressant treatment on internalising and anxiety behaviours in children: 12-year longitudinal study
BJPsych Open
Sarah M. Hutchison and Ursula Brain and Ruth E. Grunau and Boris Kuzeljevic and Mike Irvine and Louise C. Mâsse and Tim F. Oberlander
DOI: 10.1192/bjo.2022.623
03/2023

The application of epiphenotyping approaches to DNA methylation array studies of the human placenta
Epigenetics and Chromatin
DOI: 10.1186/s13072-023-00507-5
2023

Preface
Neurodevelopmental Pediatrics: Genetic and Environmental Influences
2023

Anxiety symptoms, psychological distress, and optimism in school staff: Testing associations with stressors and coping during the second year of the COVID-19 pandemic
Journal of Affective Disorders Reports
DOI: 10.1016/j.jadr.2023.100662
2023

Gestational stress and perinatal SSRIs differentially impact the maternal and neonatal microbiome-gut-brain axis
Journal of Neuroendocrinology
DOI: 10.1111/jne.13261
2023

Exogenous oxytocin administration during labor and autism spectrum disorder
American Journal of Obstetrics and Gynecology MFM
DOI: 10.1016/j.ajogmf.2023.101010
2023

Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies
Frontiers in Pharmacology
DOI: 10.3389/fphar.2023.1094698
2023

Association between prenatal antibiotic exposure and autism spectrum disorder among term births: A population-based cohort study
Paediatric and Perinatal Epidemiology
DOI: 10.1111/ppe.12972
2023

Can we more precisely classify exposure to antenatal depression and anxiety in multivariable prediction models of pregnancy and birth outcomes: a population-based cohort study
BMC Psychiatry
DOI: 10.1186/s12888-023-05284-9
2023

Response: Maternal infection, prenatal antibiotics and risk of autism in the offspring
Paediatric and Perinatal Epidemiology
DOI: 10.1111/ppe.12996
2023

The application of epiphenotyping approaches to DNA methylation array studies of the human placenta
Research Square
DOI: 10.21203/rs.3.rs-3069705
2023

A Multi-Centre, Tolerability Study of a Cannabidiol-enriched Cannabis Herbal Extract for Chronic Headaches in Adolescents: the CAN-CHA Protocol
medRxiv
DOI: 10.1101/2023.08.04.23293647
2023

Preface
Neurodevelopmental Pediatrics: Genetic and Environmental Influences
2023

Pain and symptom management in neurodevelopmental disorders: Sensory and nociceptive function/pain and symptom management
Neurodevelopmental Pediatrics: Genetic and Environmental Influences
DOI: 10.1007/978-3-031-20792-1_43
2023

Neurodevelopmental pediatrics: Genetic and environmental influences
Neurodevelopmental Pediatrics: Genetic and Environmental Influences
DOI: 10.1007/978-3-031-20792-1
2023

The PPD-ACT app in Canada: feasibility and a latent class analysis of participants with postpartum depression recruited to a psychiatric genetics study using a mobile application
BMC Psychiatry
Joanna Collaton and Cindy-Lee Dennis and Valerie H. Taylor and Sophie Grigoriadis and Tim F. Oberlander and Benicio N. Frey and Ryan Van Lieshout and Jerry Guintivano and Samantha Meltzer-Brody and James L. Kennedy and Simone N. Vigod
DOI: 10.1186/s12888-022-04363-7
11/2022

A multicentre Canadian survey of caregiver perspectives on COVID vaccine-related pain and stress for their family
British Journal of Pain
Samina Ali and Elise Kammerer and Graham Thompson and Ahmed Mater and Manasi Rajagopal and Jeffrey N Bone and Kathryn A Birnie and Tim Oberlander and Christine T Chambers and Ran D Goldman
DOI: 10.1177/20494637221090452
10/2022

Behavior regulation skills are associated with adaptive functioning in children and adolescents with prenatal alcohol exposure
Applied Neuropsychology: Child
Emily Gardiner and Sarah M. Hutchison and Kaitlyn McLachlan and Carmen Rasmussen and Jacqueline Pei and Louise C. Mâsse and Tim F. Oberlander and James N. Reynolds
DOI: 10.1080/21622965.2021.1936528
10/2022

Associations Between Prenatal Exposure to Serotonergic Medications and Biobehavioral Stress Regulation: Protocol for a Systematic Review and Meta-analysis
JMIR Research Protocols
Enav Z Zusman and Alekhya Lavu and Colleen Pawliuk and Jodi Pawluski and Sarah M Hutchison and Robert W Platt and Tim F Oberlander
DOI: 10.2196/33363
03/2022

Placebo and nocebo effects in youth: subjective thermal discomfort can be modulated by a conditioning paradigm utilizing mental states of low and high self-efficacy
British Journal of Pain
Ella Weik and Regula Neuenschwander and Karin Jensen and Tim F Oberlander and Christine Tipper
DOI: 10.1177/20494637211020042
02/2022

Medicinal cannabis in children and adolescents with autism spectrum disorder: A scoping review
Child: Care, Health and Development
Sarah Fletcher and Colleen Pawliuk and Angie Ip and Linda Huh and S. Rod Rassekh and Tim F. Oberlander and Harold Siden
DOI: 10.1111/cch.12909
01/2022

Adolescents with solid organ transplant: Using the BRIEF2 parent-report and self-report to measure parent-child agreement and everyday executive function
Applied Neuropsychology: Child
Hutchison, S.M. and Rathgeber, S.L. and De Souza, A.M. and Blydt-Hansen, T. and Mâsse, L.C. and Armstrong, K.R. and Oberlander, T.F.
DOI: 10.1080/21622965.2020.1800468
2022

The COVID-19 pandemic impacted maternal mental health differently depending on pregnancy status and trimester of gestation
Research Square
DOI: 10.21203/rs.3.rs-1167874/v1
2022

Pain in individuals with intellectual disabilities
Clinical Pain Management: A Practical Guide, Second Edition
DOI: 10.1002/9781119701170.ch42
2022

The COVID-19 pandemic impacted maternal mental health differently depending on pregnancy status and trimester of gestation
ResearchSquare
DOI: 10.21203/rs.3.rs-1167874
2022

Profiling placental DNA methylation associated with maternal SSRI treatment during pregnancy
Scientific Reports
Inkster, A.M. and Konwar, C. and Pe{\~n}aherrera, M.S. and Brain, U. and Khan, A. and Price, E.M. and Schuetz, J.M. and Portales-Casamar, ?. and Burt, A. and Marsit, C.J. and Vaillancourt, C. and Oberlander, T.F. and Robinson, W.P.
DOI: 10.1038/s41598-022-26071-8
2022

The Canadian Mother-Child Cohort Active Surveillance Initiative (CAMCCO): Comparisons between Quebec, Manitoba, Saskatchewan, and Alberta
PLoS ONE
B{\'e}rard, A. and Kaul, P. and Eltonsy, S. and Winquist, B. and Chateau, D. and Hawken, S. and Sprague, A. and Walker, M. and Bernatsky, S. and Abrahamowicz, M. and de Moura, C.S. and Vinet, ?. and Carleton, B. and Hanley, G. and Oberlander, T. and Sheehy, O. and Gomez, Y.H. and Gorgui, J. and Savu, A.
DOI: 10.1371/journal.pone.0274355
2022

Developmental profiles of children at risk for autism spectrum disorder at school entry
Autism Research
Ip, A. and Poon, B.T. and Hanley, G. and Guhn, M. and Oberlander, T.F.
DOI: 10.1002/aur.2742
2022

The association between prenatal greenspace exposure and Autism spectrum disorder, and the potentially mediating role of air pollution reduction: A population-based birth cohort study
Environment International
Pagalan, L. and Oberlander, T.F. and Hanley, G.E. and Rosella, L.C. and Bickford, C. and Weikum, W. and Lanphear, N. and Lanphear, B. and Brauer, M. and van den Bosch, M.
DOI: 10.1016/j.envint.2022.107445
2022

COVID-19 Vaccine Intentions and Perceptions Among Public School Staff of the Greater Vancouver Metropolitan Area, British Columbia, Canada
Frontiers in Public Health
Watts, A.W. and Hutchison, S.M. and Bettinger, J.A. and Gadermann, A. and Oberle, E. and Oberlander, T.F. and Goldfarb, D.M. and Lavoie, P.M. and M{\^a}sse, L.C.
DOI: 10.3389/fpubh.2022.832444
2022

Autism Risk and Perinatal Antibiotic Use
Pediatrics
Nitschke, A.S. and Karim, J.L. and Vallance, B.A. and Bickford, C. and Ip, A. and Lanphear, N. and Lanphear, B. and Weikum, W. and Oberlander, T.F. and Hanley, G.E.
DOI: 10.1542/peds.2022-057346
2022

The Impact of COVID-19 on Maternal Mental Health during Pregnancy: A Comparison between Canada and China within the CONCEPTION Cohort
International Journal of Environmental Research and Public Health
Pag{\`e}s, N. and Gorgui, J. and Wang, C. and Wang, X. and Zhao, J.-P. and Tchuente, V. and Lacasse, A. and C{\^o}t{\'e}, S. and King, S. and Muanda, F. and Mufike, Y. and Boucoiran, I. and Nuyt, A.M. and Quach, C. and Ferreira, E. and Kaul, P. and Winquist, B. and O?Donnell, K.J. and Eltonsy, S. and Chateau, D. and Hanley, G. and Oberlander, T. and Kassai, B. and Mainbourg, S. and Bernatsky, S. and Vinet, ?. and Brodeur-Doucet, A. and Demers, J. and Richeb{\'e}, P. and Zaphiratos, V. and B{\'e}rard, A.
DOI: 10.3390/ijerph191912386
2022

Profiling placental DNA methylation associated with maternal SSRI treatment during pregnancy
medRxiv
Inkster, A.M. and Konwar, C. and Pe{\~n}aherrera, M.S. and Brain, U. and Khan, A. and Price, E.M. and Schuetz, J.M. and Portales-Casamar, ?. and Burt, A. and Marsit, C.J. and Vaillancourt, C. and Oberlander, T.F. and Robinson, W.P.
DOI: 10.1101/2022.06.21.22276723
2022

Adaptive behavior, sleep, and physical activity in adolescents with fetal alcohol spectrum disorder
Research in Developmental Disabilities
Hammond, L. and Joly, V. and Kapasi, A. and Kryska, K. and Andrew, G. and Oberlander, T.F. and Pei, J. and Rasmussen, C.
DOI: 10.1016/j.ridd.2022.104366
2022

Canadian surveillance study of complex regional pain syndrome in children
Pain
Baerg, K. and Tupper, S.M. and Chu, L.M. and Cooke, N. and Dick, B.D. and Dor{\'e}-Bergeron, M.-J. and Findlay, S. and Ingelmo, P.M. and Lamontagne, C. and Mesaroli, G. and Oberlander, T.F. and Poolacherla, R. and Spencer, A.O. and Stinson, J. and Finley, G.A.
DOI: 10.1097/j.pain.0000000000002482
2022

Maternal Schizophrenia and the Risk of a Childhood Chronic Condition
Schizophrenia bulletin
Vigod, S.N. and Ray, J.G. and Cohen, E. and Wilton, A.S. and Saunders, N.R. and Barker, L.C. and Berard, A. and Dennis, C.-L. and Holloway, A.C. and Morrison, K. and Oberlander, T.F. and Hanley, G. and Tu, K. and Brown, H.K.
DOI: 10.1093/schbul/sbac091
2022

Preconception mental health and the relationship between antenatal depression or anxiety and gestational diabetes mellitus: a population-based cohort study
BMC pregnancy and childbirth
Thiele, G.A. and Ryan, D.M. and Oberlander, T.F. and Hanley, G.E.
DOI: 10.1186/s12884-022-05002-5
2022

Somatization in Adolescents With Persistent Symptoms After Concussion: A Retrospective Chart Review
The Journal of neuropsychiatry and clinical neurosciences
Green, K.E. and Purtzki, J. and Chapman, A. and Oberlander, T.F. and Silverberg, N.D. and Dhariwal, A.K.
DOI: 10.1176/appi.neuropsych.21070169
2022

The development of a patient decision aid to reduce decisional conflict about antidepressant use in pregnancy
BMC Medical Informatics and Decision Making
Hussain-Shamsy, N. and Somerton, S. and Stewart, D.E. and Grigoriadis, S. and Metcalfe, K. and Oberlander, T.F. and Schram, C. and Taylor, V.H. and Dennis, C.-L. and Vigod, S.N.
DOI: 10.1186/s12911-022-01870-1
2022

Data visualization as an intervention for pediatric chronic pain: a pilot feasibility study protocol for a randomized controlled crossover trial
Pilot and Feasibility Studies
Boerner, K.E. and Desai, U. and MacLean, K.E. and Munzner, T. and Foladare, H. and Gill, J. and Oberlander, T.F.
DOI: 10.1186/s40814-022-01170-5
2022

The influence of early-life residential exposure to different vegetation types and paved surfaces on early childhood development: A population-based birth cohort study
Environment International
Jarvis, I. and Sbihi, H. and Davis, Z. and Brauer, M. and Czekajlo, A. and Davies, H.W. and Gergel, S.E. and Guhn, M. and Jerrett, M. and Koehoorn, M. and Nesbitt, L. and Oberlander, T.F. and Su, J. and van den Bosch, M.
DOI: 10.1016/j.envint.2022.107196
2022

Neighborhood environmental exposures and incidence of attention deficit/hyperactivity disorder: A population-based cohort study
Environment International
Yuchi, W. and Brauer, M. and Czekajlo, A. and Davies, H.W. and Davis, Z. and Guhn, M. and Jarvis, I. and Jerrett, M. and Nesbitt, L. and Oberlander, T.F. and Sbihi, H. and Su, J. and van den Bosch, M.
DOI: 10.1016/j.envint.2022.107120
2022

School staff and teachers during the second year of COVID-19: Higher anxiety symptoms, higher psychological distress, and poorer mental health compared to the general population
Journal of Affective Disorders Reports
Hutchison, S.M. and Watts, A. and Gadermann, A. and Oberle, E. and Oberlander, T.F. and Lavoie, P.M. and Mâsse, L.C.
DOI: 10.1016/j.jadr.2022.100335
2022

Ensuring Equity and Inclusion in Virtual Care Best Practices for Diverse Populations of Youth with Chronic Pain
Healthcare quarterly (Toronto, Ont.)
Birnie, K.A. and Killackey, T. and Backlin, G. and Gavin, F. and Harris, C. and Jordan, I. and Kim, L. and Marianayagam, J. and Swidrovich, J. and Lalonde, C. and Tunji-Ajayi, L. and Oberlander, T. and Kirby-Allen, M. and Lambert, S. and Siden, H. and Swidrovich, J. and Noel, M. and Lalloo, C. and Stinson, J.
DOI: 10.12927/hcq.2022.26778
2022

The COVID-19 Pandemic Impacted Maternal Mental Health Differently Depending on Pregnancy Status and Trimester of Gestation
International Journal of Environmental Research and Public Health
Bérard, A. and Gorgui, J. and Tchuente, V. and Lacasse, A. and Gomez, Y.-H. and Côté, S. and King, S. and Muanda, F. and Mufike, Y. and Boucoiran, I. and Nuyt, A.M. and Quach, C. and Ferreira, E. and Kaul, P. and Winquist, B. and O?donnell, K.J. and Eltonsy, S. and Chateau, D. and Zhao, J.-P. and Hanley, G. and Oberlander, T. and Kassai, B. and Mainbourg, S. and Bernatsky, S. and Vinet, ?. and Brodeur-Doucet, A. and Demers, J. and Richebé, P. and Zaphiratos, V.
DOI: 10.3390/ijerph19052926
2022

A text messaging intervention and quality of life in adolescents with solid organ transplants
Pediatric Transplantation
Rathgeber, S.L. and Hutchison, S.M. and De Souza, A.-M. and Lester, R. and Blydt-Hansen, T. and Human, D.G. and Guttman, O. and Oberlander, T. and Armstrong, K.R.
DOI: 10.1111/petr.14219
2022

Complex chronic conditions among children born to women with schizophrenia
Schizophrenia Research
Toufeili, A. and Cohen, E. and Ray, J.G. and Wilton, A.S. and Brown, H.K. and Saunders, N.R. and Dennis, C.L. and Holloway, A.C. and Morrison, K.M. and Hanley, G.E. and Oberlander, T.F. and Bérard, A. and Tu, K. and Barker, L.C. and Vigod, S.N.
DOI: 10.1016/j.schres.2021.12.018
2022

A cross-sectional study of the relationship between CYP2D6 and CYP2C19 variations and depression symptoms, for women taking SSRIs during pregnancy
Archives of Women's Mental Health
Hippman, C. and Slomp, C. and Morris, E. and Batallones, R. and Inglis, A. and Carrion, P. and Brain, U. and Higginson, M. and Wright, G.E.B. and Balneaves, L.G. and Ryan, D. and Nislow, C. and Ross, C.J.D. and Gaedigk, A. and Oberlander, T.F. and Austin, J.
DOI: 10.1007/s00737-021-01149-w
2022

Antidepressant exposure in pregnancy and child sensorimotor and visuospatial development
Journal of Psychiatric Research
Megan Galbally and Stuart J. Watson and Olav Spigset and Philip Boyce and Tim F. Oberlander and Andrew J. Lewis
DOI: 10.1016/j.jpsychires.2020.11.035
11/2021

Associations Between Prenatal Exposure to Serotonergic Medications and Biobehavioral Stress Regulation: Protocol for a Systematic Review and Meta-analysis (Preprint)
Enav Z Zusman and Alekhya Lavu and Colleen Pawliuk and Jodi Pawluski and Sarah M Hutchison and Robert W Platt and Tim F Oberlander
DOI: 10.2196/preprints.33363
09/2021

Prenatal antidepressant exposure and sex differences in neonatal corpus callosum microstructure
Developmental Psychobiology
Kayleigh S. J. Campbell and Lynne J. Williams and Bruce H. Bjornson and Ella Weik and Ursula Brain and Ruth E. Grunau and Steven P. Miller and Tim F. Oberlander
DOI: 10.1002/dev.22125
09/2021

The Association between Cumulative Lifetime Exposure to Greenspace and Early Childhood Development – Is the Relation Mediated by Reduction in Air Pollution and Noise?
SSRN
Jarvis, I. and Davis, Z. and Sbihi, H. and Brauer, M. and Czekajlo, A. and Davies, H.W. and Gergel, S.E. and Guhn, M. and Jerrett, M. and Koehoorn, M. and Oberlander, T.F. and Su, J. and van den Bosch, M.
2021

Perinatal selective serotonin reuptake inhibitor (SSRI) and other antidepressant exposure effects on anxiety and depressive behaviors in offspring: A review of findings in humans and rodent models
Reproductive Toxicology
Hutchison, S.M. and Mâsse, L.C. and Pawluski, J.L. and Oberlander, T.F.
DOI: 10.1016/j.reprotox.2020.11.013
2021

Prenatal exposure to maternal depression is related to the functional connectivity organization underlying emotion perception in 8-10-month-old infants – Preliminary findings
Infant Behavior and Development
Rotem-Kohavi, N. and Virji-Babul, N. and Oberlander, T.F.
DOI: 10.1016/j.infbeh.2021.101545
2021

Epidural Analgesia and Autism Spectrum Disorder Risk - The Challenges Inherent in Complex Observational Research
JAMA Pediatrics
Hanley, G.E. and Ip, A. and Oberlander, T.F.
DOI: 10.1001/jamapediatrics.2021.0382
2021

Prenatal antidepressant exposure and child development at kindergarten age: a population-based study
Pediatric Research
Park, M. and Hanley, G.E. and Guhn, M. and Oberlander, T.F.
DOI: 10.1038/s41390-020-01269-6
2021

The Association between Cumulative Lifetime Exposure to Greenspace and Early Childhood Development – Is the Relation Mediated by Reduction in Air Pollution and Noise?
SSRN
DOI: 10.2139/ssrn.3831160
2021

Prenatal Stress and Child Development
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1
2021

Preface
Prenatal Stress and Child Development
2021

The other side of prenatal depression: Developmental outcomes associated with antidepressant medication therapy
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1_19
2021

The microbiome-gut-brain axis: A new window to view the impact of prenatal stress on early neurodevelopment
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1_8
2021

Prenatal stress and child development-pathways, mechanisms and interventions
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1_1
2021

Prenatal stress and child development: The future that lies ahead
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1_21
2021

Correspondence: Adolescents during COVID-19: Youth with disabilities more likely to report challenges with anxiety and mental health
Journal of Affective Disorders Reports
Hutchison, S.M. and Holley, P. and Manuel, A. and Mâsse, L.C. and Oberlander, T.F. and Jedwab, J.
DOI: 10.1016/j.jadr.2020.100072
2021

Preliminary insights into the genetic architecture of postpartum depressive symptom severity using polygenic risk scores
Personalized Medicine in Psychiatry
Pouget, J.G. and Taylor, V.H. and Dennis, C.-L. and Grigoriadis, S. and Oberlander, T. and Frey, B.N. and Van Lieshout, R. and Guintivano, J. and Meltzer-Brody, S. and Kennedy, J.L. and Vigod, S.N.
DOI: 10.1016/j.pmip.2021.100081
2021

Improving the regulation of medical cannabis in Canada to better serve pediatric patients
CMAJ
Huntsman, R.J. and Kelly, L.E. and Alcorn, J. and Appendino, J.P. and Bélanger, R.E. and Crooks, B. and Finkelstein, Y. and Gilpin, A. and Lewis, E. and Litalien, C. and Jacobs, J. and Moore-Hepburn, C. and Oberlander, T. and Rassekh, S.R. and Repetski, A.E. and Rieder, M.J. and Shackelford, A. and Siden, H. and Szafron, M. and T'Jong, G.W. and Vaillancourt, R.
DOI: 10.1503/cmaj.202169
2021

Improving the regulation of medical cannabis in Canada to better serve pediatric patients,Améliorer la réglementation du cannabis médical au Canada pour mieux servir les patients pédiatriques
CMAJ
Huntsman, R.J. and Kelly, L.E. and Alcorn, J. and Appendino, J.P. and Bélanger, R.E. and Crooks, B. and Finkelstein, Y. and Gilpin, A. and Lewis, E. and Litalien, C. and Jacobs, J. and Moore-Hepburn, C. and Oberlander, T. and Rassekh, S.R. and Repetski, A.E. and Rieder, M.J. and Shackelford, A. and Siden, H. and Szafron, M. and T Jong, G.W. and Vaillancourt, R.
DOI: 10.1503/cmaj.202169-f
2021

Assessing the association between lifetime exposure to greenspace and early childhood development and the mediation effects of air pollution and noise in Canada: a population-based birth cohort study
The Lancet. Planetary health
Jarvis, I. and Davis, Z. and Sbihi, H. and Brauer, M. and Czekajlo, A. and Davies, H.W. and Gergel, S.E. and Guhn, M. and Jerrett, M. and Koehoorn, M. and Oberlander, T.F. and Su, J. and van den Bosch, M.
DOI: 10.1016/S2542-5196(21)00235-7
2021

Maternal Serotonin Reuptake Inhibitor Antidepressants Have Acute Effects on Fetal Heart Rate Variability in Late Gestation
Frontiers in Psychiatry
Campbell, K.S.J. and Collier, A.C. and Irvine, M.A. and Brain, U. and Rurak, D.W. and Oberlander, T.F. and Lim, K.I.
DOI: 10.3389/fpsyt.2021.680177
2021

Association of Epidural Analgesia during Labor and Delivery with Autism Spectrum Disorder in Offspring
JAMA - Journal of the American Medical Association
Hanley, G.E. and Bickford, C. and Ip, A. and Lanphear, N. and Lanphear, B. and Weikum, W. and Zwaigenbaum, L. and Oberlander, T.F.
DOI: 10.1001/jama.2021.14986
2021

Symptoms, adverse events, and outcomes in the use of medicinal cannabis in children and adolescents with autism spectrum disorder: A scoping review protocol
JBI Evidence Synthesis
Fletcher, S. and Pawliuk, C. and Ip, A. and Oberlander, T. and Siden, H.
DOI: 10.11124/JBIES-20-00001
2021

The association between natural environments and childhood mental health and development: A systematic review and assessment of different exposure measurements
International Journal of Hygiene and Environmental Health
Davis, Z. and Guhn, M. and Jarvis, I. and Jerrett, M. and Nesbitt, L. and Oberlander, T. and Sbihi, H. and Su, J. and van den Bosch, M.
DOI: 10.1016/j.ijheh.2021.113767
2021

Impact of the COVID-19 Pandemic on Maternal Mental Health during Pregnancy: The CONCEPTION Study – Phase I
SSRN
Bérard, A. and Lacasse, A. and Gomez, Y.-H. and Gorgui, J. and Côté, S.M. and King, S. and Tchuente, V. and Muanda, F.T. and Lumu, Y.M. and Boucoiran, I. and Nuyt, A.-M. and Quach, C.T. and Ferreira, E. and Kaul, P. and Winquist, B. and O?Donnell, K.J. and Eltonsy, S. and Chateau, D. and Zhao, J.-P. and Hanley, G.E. and Oberlander, T.F. and Kassai, B. and Mainbourg, S. and Bernatsky, S. and Vinet, ?. and Brodeur-Doucet, A. and Demers, J. and Richebé, P. and Zaphiratos, V. and Wang, C. and Wang, X.
DOI: 10.2139/ssrn.3777974
2021

Symptoms, adverse events, and outcomes in the use of medicinal cannabis in children and adolescents with autism spectrum disorder: a scoping review protocol.
JBI evidence synthesis
Fletcher S and Pawliuk C and Ip A and Oberlander T and Siden H
DOI: 10.11124/jbies-20-00001
PubMed: 33165173
11/2020

Conditioned Placebo- and Nocebo-Like Effects in Adolescents: The Role of Conscious Awareness, Sensory Discrimination, and Executive Function.
Frontiers in psychiatry
Neuenschwander R and Weik E and Tipper CM and Jensen K and Oberlander TF
DOI: 10.3389/fpsyt.2020.586455
PubMed: 33329131
11/2020

Effects of maternal depression and prenatal SSRI exposure on executive functions and susceptibility to household chaos in 6-year-old children: prospective cohort study
BJPsych Open
Gurpreet Dhaliwal and Whitney M. Weikum and Alexia Jolicoeur-Martineau and Ursula Brain and Ruth E. Grunau and Tim F. Oberlander
DOI: 10.1192/bjo.2020.73
09/2020

The PPD-ACT App: Feasibility of a mobile application for recruiting women with postpartum depression and psychosis to a psychiatric genetics study (Preprint)
Joanna Collaton and Cindy-Lee Dennis and Valerie H Taylor and Sophie Grigoriadis and Tim F Oberlander and Benicio N Frey and Ryan Van Lieshout and Jerry Guintivano and Samantha Meltzer-Brody and James L Kennedy and Simone N Vigod
DOI: 10.2196/preprints.24327
09/2020

The Association Between Antidepressant Exposure and Birth Defects-Are We There Yet?
JAMA psychiatry
Wisner KL and Oberlander TF and Huybrechts KF
DOI: 10.1001/jamapsychiatry.2020.1512
PubMed: 32777006
08/2020

Blood DHA, Choline, and Lutein Concentrations and Their Correlation with Cognitive and Behavioral Outcomes in 18-Month Old Toddlers: Preliminary Findings.
Current developments in nutrition
Rossen L and Montgomery S and Zibrik D and Dyer R and Oberlander T and Lamers Y
05/2020

Socieconomic status and psychotropic medicine use during pregnancy: a population-based study in British Columbia, Canada.
Archives of women's mental health
Hanley GE and Park M and Oberlander TF
DOI: 10.1007/s00737-020-01034-y
PubMed: 32409987
05/2020

Nutritional Status in Breastfed 18-Month Old Toddlers: Cross-Sectional Findings.
Current developments in nutrition
Montgomery S and Ho G and Rossen L and Zibrik D and Dyer R and Oberlander T and Lamers Y
05/2020

Plasma Choline Concentration Is Positively Correlated with Visual Acuity in 18-Month Old Toddlers: Preliminary Findings.
Current developments in nutrition
Montgomery S and Rossen L and Zibrik D and Dyer R and Oberlander T and Lamers Y
05/2020

"Placebo by Proxy" and "Nocebo by Proxy" in Children: A Review of Parents' Role in Treatment Outcomes.
Frontiers in psychiatry
Czerniak E and Oberlander TF and Weimer K and Kossowsky J and Enck P
DOI: 10.3389/fpsyt.2020.00169
PubMed: 32218746
03/2020

Differences in White Matter Microstructure Among Children With Developmental Coordination Disorder.
JAMA network open
Brown-Lum M and Izadi-Najafabadi S and Oberlander TF and Rauscher A and Zwicker JG
DOI: 10.1001/jamanetworkopen.2020.1184
PubMed: 32186744
03/2020

The role of glucocorticoid and mineralocorticoid receptor DNA methylation in antenatal depression and infant stress regulation.
Psychoneuroendocrinology
Galbally M and Watson SJ and van IJzendoorn M and Saffery R and Ryan J and de Kloet ER and Oberlander TF and Lappas M and Lewis AJ
DOI: 10.1016/j.psyneuen.2020.104611
PubMed: 32087522
02/2020

Decision-making about antidepressant medication use in pregnancy: a comparison between women making the decision in the preconception period versus in pregnancy.
BMC psychiatry
Barker LC and Dennis CL and Hussain-Shamsy N and Stewart DE and Grigoriadis S and Metcalfe K and Oberlander TF and Schram C and Taylor VH and Vigod SN
DOI: 10.1186/s12888-020-2478-8
PubMed: 32033547
02/2020

Advanced neuroimaging: A window into the neural correlates of fetal programming related to prenatal exposure to maternal depression and SSRIs.
Seminars in perinatology
Rotem-Kohavi N and Williams LJ and Oberlander TF
DOI: 10.1016/j.semperi.2020.151223
PubMed: 32122645
01/2020

Correction to "In Utero Exposure to Citalopram Mitigates Maternal Stress Effects on Fetal Brain Development".
ACS chemical neuroscience
Velasquez JC and Zhao Q and Chan Y and Galindo LCM and Simasotchi C and Wu D and Hou Z and Herod SM and Oberlander TF and Gil S and Fournier T and Burd I and Andrews AM and Bonnin A
DOI: 10.1021/acschemneuro.9b00683
PubMed: 31912736
01/2020

Identification of Pediatric Autism Spectrum Disorder Cases Using Health Administrative Data
Autism Research
Bickford, C.D. and Oberlander, T.F. and Lanphear, N.E. and Weikum, W.M. and Janssen, P.A. and Ouellette-Kuntz, H. and Hanley, G.E.
DOI: 10.1002/aur.2252
2020

Prenatal SSRI antidepressant use and maternal internalizing symptoms during pregnancy and postpartum: Exploring effects on infant temperament trajectories for boys and girls.
Journal of Affective Disorders
Erickson NL and Hancock GR and Oberlander TF and Brain U and Grunau RE and Gartstein MA
DOI: 10.1016/j.jad.2019.08.003
PubMed: 31437600
08/2019

Transcranial direct current stimulation (tDCS) for depression in pregnancy: A pilot randomized controlled trial.
Brain stimulation
Vigod SN and Murphy KE and Dennis CL and Oberlander TF and Ray JG and Daskalakis ZJ and Blumberger DM
DOI: 10.1016/j.brs.2019.06.019
PubMed: 31257092
06/2019

In Utero Exposure to Citalopram Mitigates Maternal Stress Effects on Fetal Brain Development.
ACS chemical neuroscience
Velasquez JC and Zhao Q and Chan Y and Galindo LCM and Simasotchi C and Wu D and Hou Z and Herod SM and Oberlander TF and Gil S and Fournier T and Burd I and Andrews AM and Bonnin A
DOI: 10.1021/acschemneuro.9b00180
PubMed: 31184110
06/2019

Hub distribution of the brain functional networks of newborns prenatally exposed to maternal depression and SSRI antidepressants.
Depression and anxiety
Rotem-Kohavi N and Williams LJ and Muller AM and Abdi H and Virji-Babul N and Bjornson BH and Brain U and Werker JF and Grunau RE and Miller SP and Oberlander TF
DOI: 10.1002/da.22906
PubMed: 31066992
05/2019

126 The Canadian Neonatal Brain Platform: A three-pillar approach.
Paediatrics & Child Health
Luck D and Ding Y and Luu TM and Oberlander T and Grunau R and Miller S and Lodygensky G
05/2019

Impact of Prenatal Selective Serotonin Reuptake Inhibitor Antidepressant Exposure and Maternal Mood on Physical Activity, Dietary Intake, and Markers of Adiposity at Age 6 Years.
Journal of developmental and behavioral pediatrics : JDBP
Hutchison SM and Mâsse LC and Glier MB and Brain U and Devlin AM and Oberlander TF
DOI: 10.1097/dbp.0000000000000658
PubMed: 30950906
05/2019

Calmer: a robot for managing acute pain effectively in preterm infants in the neonatal intensive care unit.
Pain reports
Holsti L and MacLean K and Oberlander T and Synnes A and Brant R
DOI: 10.1097/PR9.0000000000000727
PubMed: 31041426
03/2019

Myelin Water Fraction Imaging of the Brain in Children with Prenatal Alcohol Exposure
Alcoholism: Clinical and Experimental Research
McLachlan, K. and Vavasour, I. and MacKay, A. and Brain, U. and Oberlander, T. and Loock, C. and Reynolds, J.N. and Beaulieu, C.
DOI: 10.1111/acer.14024
2019

Evaluating pain in cerebral palsy: comparing assessment tools using the International Classification of Functioning, Disability and Health
Disability and Rehabilitation
Schiariti, V. and Oberlander, T.F.
DOI: 10.1080/09638288.2018.1472818
2019

Impact of prenatal selective serotonin reuptake inhibitor antidepressant exposure and maternal mood on physical activity, dietary intake, and markers of adiposity at age 6 years
Journal of Developmental and Behavioral Pediatrics
Hutchison, S.M. and Mâsse, L.C. and Glier, M.B. and Brain, U. and Devlin, A.M. and Oberlander, T.F.
DOI: 10.1097/DBP.0000000000000658
2019

Risk factors for hospitalizations associated with depression among women during the years around a birth: A retrospective cohort study
International Journal of Population Data Science
Fairthorne, J.C. and Hanley, G.E. and Brant, R. and Oberlander, T.F.
DOI: 10.23889/ijpds.v4i1.453
2019

A patient decision aid for antidepressant use in pregnancy: Pilot randomized controlled trial
Journal of Affective Disorders
Vigod, S.N. and Hussain-Shamsy, N. and Stewart, D.E. and Grigoriadis, S. and Metcalfe, K. and Oberlander, T.F. and Schram, C. and Taylor, V.H. and Dennis, C.-L.
DOI: 10.1016/j.jad.2019.01.051
2019

Prevalence and characteristics of adults with fetal alcohol spectrum disorder in corrections: A Canadian case ascertainment study
BMC Public Health
McLachlan, K. and McNeil, A. and Pei, J. and Brain, U. and Andrew, G. and Oberlander, T.F.
DOI: 10.1186/s12889-018-6292-x
2019

A 6-year longitudinal study: Are maternal depressive symptoms and Selective Serotonin Reuptake Inhibitor (SSRI) antidepressant treatment during pregnancy associated with everyday measures of executive function in young children?
Early Human Development
Hutchison, S.M. and Mâsse, L.C. and Brain, U. and Oberlander, T.F.
DOI: 10.1016/j.earlhumdev.2018.10.009
2019

Association of Prenatal Exposure to Air Pollution with Autism Spectrum Disorder
JAMA Pediatrics
Pagalan, L. and Bickford, C. and Weikum, W. and Lanphear, B. and Brauer, M. and Lanphear, N. and Hanley, G.E. and Oberlander, T.F. and Winters, M.
DOI: 10.1001/jamapediatrics.2018.3101
2019

Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression
Archives of Women's Mental Health
Pawluski, J.L. and Brain, U. and Hammond, G.L. and Oberlander, T.F.
DOI: 10.1007/s00737-018-0931-1
2019

Alterations in Resting-State Networks Following In Utero Selective Serotonin Reuptake Inhibitor Exposure in the Neonatal Brain
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Rotem-Kohavi, N. and Williams, L.J. and Virji-Babul, N. and Bjornson, B.H. and Brain, U. and Werker, J.F. and Grunau, R.E. and Miller, S.P. and Oberlander, T.F.
DOI: 10.1016/j.bpsc.2018.08.004
2019

Variations from morning to afternoon of middle cerebral and umbilical artery blood flow, and fetal heart rate variability, and fetal characteristics in the normally developing fetus
Journal of Clinical Ultrasound
Tehila Avitan and Ari Sanders and Ursula Brain and Dan Rurak and Tim F Oberlander and Ken Lim
DOI: 10.1002/jcu.22569
05/2018

Perinatal selective serotonin reuptake inhibitor (SSRI) effects on body weight at birth and beyond: A review of animal and human studies
Reproductive Toxicology
Sarah M. Hutchison and Louise C. Mâsse and Jodi L. Pawluski and Tim F. Oberlander
DOI: 10.1016/j.reprotox.2018.02.004
04/2018

Perinatal selective serotonin reuptake inhibitor medication (SSRI) effects on social behaviors, neurodevelopment and the epigenome
Neuroscience & Biobehavioral Reviews
Mary Gemmel and Eszter Bögi and Christina Ragan and Mariah Hazlett and Michal Dubovicky and Daniel L. van den Hove and Tim F. Oberlander and Thierry D. Charlier and Jodi L. Pawluski
DOI: 10.1016/j.neubiorev.2017.04.023
02/2018

Maternal depression trajectories from pregnancy to 3 years postpartum are associated with children’s behavior and executive functions at 3 and 6 years
Archives of Women's Mental Health
Mina Park and Ursula Brain and Ruth E. Grunau and Adele Diamond and Tim F. Oberlander
DOI: 10.1007/s00737-017-0803-0
01/2018

Depressed Women of Low Socioeconomic Status Have High Numbers of Physician Visits in the Year Before Pregnancy: Implications for Care
Journal of Clinical Medicine Research
Jenny Fairthorne and Gillian E. Hanley and Tim F. Oberlander
DOI: 10.14740/jocmr3377w
2018

Children's stress regulation mediates the association between prenatal maternal mood and child executive functions for boys, but not girls
Development and Psychopathology
Neuenschwander, R. and Hookenson, K. and Brain, U. and Grunau, R.E. and Devlin, A.M. and Weinberg, J. and Diamond, A. and Oberlander, T.F.
DOI: 10.1017/S095457941800041X
2018

In-utero Selective Serotonin Reuptake Inhibitor Antidepressant Exposure: Fetal Programing and Developmental Interactions With Context
Clinical Pharmacology and Therapeutics
Park, M. and Oberlander, T.F.
DOI: 10.1002/cpt.1134
2018

Socioeconomic status and treatment of depression during pregnancy: A retrospective population-based cohort study in British Columbia, Canada
Archives of Women's Mental Health
Hanley, G.E. and Park, M. and Oberlander, T.F.
DOI: 10.1007/s00737-018-0866-6
2018

Born to be Wise: A population registry data linkage protocol to assess the impact of modifiable early-life environmental exposures on the health and development of children
BMJ Open
Van Den Bosch, M. and Brauer, M. and Burnett, R. and Davies, H.W. and Davis, Z. and Guhn, M. and Jarvis, I. and Nesbitt, L. and Oberlander, T. and Rugel, E. and Sbihi, H. and Su, J.G. and Jerrett, M.
DOI: 10.1136/bmjopen-2018-026954
2018

Unpacking the Heterogeneity of Cognitive Functioning in Children and Adolescents with Fetal Alcohol Spectrum Disorder: Determining the Role of Moderators and Strengths
Advances in Neurodevelopmental Disorders
Kaitlyn McLachlan and Angelina Paolozza and Katrina Kully-Martens and Elodie Portales-Casamar and Paul Pavlidis and Gail Andrew and Ana Hanlon-Dearman and Christine Loock and Audrey McFarlane and Sarah M. Nikkel and Jacqueline Pei and Tim F. Oberlander and Dawa Samdup and James N. Reynolds and Carmen Rasmussen
DOI: 10.1007/s41252-017-0034-4
09/2017

Variations in Neurodevelopmental Outcomes in Children with Prenatal SSRI Antidepressant Exposure
Birth Defects Research
Naama Rotem-Kohavi and Tim F. Oberlander
DOI: 10.1002/bdr2.1076
07/2017

Response to “use of domperidone and risk of ventricular arrhythmia in the postpartum period: Getting to the heart of the matter”
Pharmacoepidemiology and Drug Safety
Kate Smolina and Steve Morgan and Barbara Mintzes and Gillian Hanley and Tim Oberlander
DOI: 10.1002/pds.4229
07/2017

Infants and adults have similar regional functional brain organization for the perception of emotions
Neuroscience Letters
N. Rotem-Kohavi and T.F. Oberlander and N. Virji-Babul
DOI: 10.1016/j.neulet.2017.04.031
05/2017

HOUSEHOLD CHAOS, MATERNAL DEPRESSION AND PRENATAL SSRI EXPOSURE INTERACT TO AFFECT EXECUTIVE FUNCTION OF 6 YEAR OLD CHILDREN.
Paediatrics & Child Health
Dhaliwal G and Weikum W and Jolicoeur-Martineau A and Brain U and Grunau R and Oberlander T
DOI: 10.1093/pch/pxx086.019
05/2017

Afternoon cortisol provides a link between self-regulated anger and peer-reported aggression in typically developing children in the school context
Developmental Psychobiology
Eva Oberle and Kaitlyn McLachlan and Nicole L.A. Catherine and Ursula Brain and Kimberly A. Schonert-Reichl and Joanne Weinberg and Tim F. Oberlander
DOI: 10.1002/dev.21522
05/2017

Disentangling Maternal Depression and Antidepressant Use During Pregnancy as Risks for Autism in Children
JAMA
Tim F. Oberlander and Lonnie Zwaigenbaum
DOI: 10.1001/jama.2017.3414
04/2017

The Risk of Teenage Motherhood Decreases in A Dose Response Fashion With Increasing SES: A Population-Based Study From British Columbia, Canada
JWHG
Jenny Fairthorne
DOI: 10.17303/jwhg.2017.4.104
03/2017

Antenatal exposure to antidepressants is associated with altered brain development in very preterm-born neonates
Neuroscience
Samantha K. Podrebarac and Emma G. Duerden and Vann Chau and Ruth E. Grunau and Anne Synnes and Tim F. Oberlander and Steven P. Miller
DOI: 10.1016/j.neuroscience.2016.11.025
02/2017

Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation
Neuroscience
S. Brummelte and E. Mc Glanaghy and A. Bonnin and T.F. Oberlander
DOI: 10.1016/j.neuroscience.2016.02.037
02/2017

Predictors of Recovery from Depression and Anxiety in Women: A Longitudinal Study from Childbirth to 6 Years
Canadian Journal of Psychiatry
Shankar, R. and Badker, R. and Brain, U. and Oberlander, T.F. and Misri, S.
DOI: 10.1177/0706743716677725
2017

Developmental origins of self-regulation: Prenatal maternal stress and psychobiological development during childhood
Parental Stress and Early Child Development: Adaptive and Maladaptive Outcomes
Neuenschwander, R. and Oberlander, T.F.
DOI: 10.1007/978-3-319-55376-4_6
2017

Post-Partum Depression and Infant Crying Behavior
Encyclopedia on Early Childhood Development
2017

Children’s stress regulation mediates the association between depressed and/or anxious prenatal maternal mood and child executive functions for boys, but not girls
Development and Psychopathology
2017

SLC6A4promoter region methylation and socio-emotional stress response in very preterm and full-term infants
Epigenomics
Rosario Montirosso and Livio Provenzi and Roberto Giorda and Monica Fumagalli and Francesco Morandi and Ida Sirgiovanni and Uberto Pozzoli and Ruth Grunau and Tim F Oberlander and Fabio Mosca and Renato Borgatti
DOI: 10.2217/epi-2016-0010
07/2016

Genetic variation in catechol-O-methyltransferase modifies effects of clonidine treatment in chronic fatigue syndrome
The Pharmacogenomics Journal
K T Hall and J Kossowsky and T F Oberlander and T J Kaptchuk and J P Saul and V B Wyller and E Fagermoen and D Sulheim and J Gjerstad and A Winger and K J Mukamal
DOI: 10.1038/tpj.2016.53
07/2016

Sculpting infant soothability: the role of prenatal SSRI antidepressant exposure and neonatalSLC6A4methylation status
Developmental Psychobiology
Maria A. Gartstein and Kaia V. Hookenson and Ursula Brain and Angela M. Devlin and Ruth E. Grunau and Tim F. Oberlander
DOI: 10.1002/dev.21414
06/2016

The association between domperidone and ventricular arrhythmia in the postpartum period
Pharmacoepidemiology and Drug Safety
Kate Smolina and Barbara Mintzes and Gillian E. Hanley and Tim F. Oberlander and Steven G. Morgan
DOI: 10.1002/pds.4035
06/2016

Dysregulation of the cortisol diurnal rhythm following prenatal alcohol exposure and early life adversity
Alcohol
Kaitlyn McLachlan and Carmen Rasmussen and Tim F. Oberlander and Christine Loock and Jacqueline Pei and Gail Andrew and James Reynolds and Joanne Weinberg
DOI: 10.1016/j.alcohol.2016.03.003
06/2016

Developmental Effects of Prenatal Selective Serotonin Reuptake Inhibitor Exposure in Perspective: Are We Comparing Apples to Apples?
Journal of the American Academy of Child & Adolescent Psychiatry
Tim F. Oberlander and Simone N. Vigod
DOI: 10.1016/j.jaac.2016.02.012
05/2016

Postpartum Hemorrhage and Use of Serotonin Reuptake Inhibitor Antidepressants in Pregnancy
Obstetrics & Gynecology
Gillian E. Hanley and Kate Smolina and Barbara Mintzes and Tim F. Oberlander and Steven G. Morgan
DOI: 10.1097/aog.0000000000001200
03/2016

A patient decision aid for antidepressant use in pregnancy: study protocol for a randomized controlled trial
Trials
Simone Vigod and Neesha Hussain-Shamsy and Sophie Grigoriadis and Louise M. Howard and Kelly Metcalfe and Tim F. Oberlander and Carrie Schram and Donna E. Stewart and Valerie H. Taylor and Cindy-Lee Dennis
DOI: 10.1186/s13063-016-1233-4
02/2016

Postpartum domperidone use in British Columbia: a retrospective cohort study
CMAJ Open
K. Smolina and S. G. Morgan and G. E. Hanley and T. F. Oberlander and B. Mintzes
DOI: 10.9778/cmajo.20150067
01/2016

Fetal Effects of In Utero Serotonin Reuptake Inhibitor (SRI) Antidepressant Exposure
Fetal Development
Gillian Hanley and Kaia Hookenson and Dan Rurak and Tim F. Oberlander
DOI: 10.1007/978-3-319-22023-9_18
2016

Postpartum Hemorrhage and Use of Serotonin Reuptake Inhibitor Antidepressants in Pregnancy
Obstetrics and Gynecology
Hanley, G.E. and Smolina, K. and Mintzes, B. and Oberlander, T.F. and Morgan, S.G.
DOI: 10.1097/AOG.0000000000001200
2016

Pain
Health Care for People with Intellectual and Developmental Disabilities Across the Lifespan
Barney, C.C. and Belew, J.L. and Valkenburg, A.J. and Symons, F.J. and Oberlander, T.F.
DOI: 10.1007/978-3-319-18096-0_143
2016

A randomized controlled trial of eye shields and earmuffs to reduce pain response of preterm infants
Journal of Neonatal Nursing
Marilyn Aita and Céline Goulet and Tim F. Oberlander and Laurie Snider and Celeste Johnston
DOI: 10.1016/j.jnn.2014.11.004
06/2015

Trends and Determinants of Prescription Drug Use during Pregnancy and Postpartum in British Columbia, 2002–2011: A Population-Based Cohort Study
PLOS ONE
Kate Smolina and Gillian E. Hanley and Barbara Mintzes and Tim F. Oberlander and Steve Morgan
DOI: 10.1371/journal.pone.0128312
05/2015

Prenatal exposure to serotonin reuptake inhibitor antidepressants and childhood behavior
Pediatric Research
Gillian E. Hanley and Ursula Brain and Tim F. Oberlander
DOI: 10.1038/pr.2015.77
04/2015

Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates
Epigenetics
DOI: 10.1080/15592294.2015.1026031
04/2015

Enhancing cognitive and social–emotional development through a simple-to-administer mindfulness-based school program for elementary school children: A randomized controlled trial.
Developmental Psychology
Kimberly A. Schonert-Reichl and Eva Oberle and Molly Stewart Lawlor and David Abbott and Kimberly Thomson and Tim F. Oberlander and Adele Diamond
DOI: 10.1037/a0038454
01/2015

Do We Know If They Work and If They Are Safe
The Science and Ethics of Antipsychotic Use in Children
Dean Elbe and Edel Mc Glanaghy and Tim F. Oberlander
DOI: 10.1016/b978-0-12-800016-8.00003-9
2015

Do We Know If They Work and If They Are Safe: Second-Generation Antipsychotics for Treatment of Autism Spectrum Disorders and Disruptive Behavior Disorders in Children and Adolescents
The Science and Ethics of Antipsychotic Use in Children
Elbe, D. and Mc Glanaghy, E. and Oberlander, T.F.
DOI: 10.1016/B978-0-12-800016-8.00003-9
2015

The Impact of Maternal Positive and Negative Affect on Fetal Physiology and Diurnal Patterns
The Israel journal of psychiatry and related sciences
Hanley, Gillian and Rurak, Dan and Lim, Ken and Brain, Ursula and Oberlander, Tim
11/2014

Transcranial direct current stimulation (tDCS) for treatment of major depression during pregnancy: study protocol for a pilot randomized controlled trial
Trials
Simone Vigod and Cindy-Lee Dennis and Zafiris Daskalakis and Kellie Murphy and Joel Ray and Tim Oberlander and Sarah Somerton and Neesha Hussain-Shamsy and Daniel Blumberger
DOI: 10.1186/1745-6215-15-366
09/2014

The symphonic structure of childhood stress reactivity: Patterns of sympathetic, parasympathetic, and adrenocortical responses to psychological challenge
Development and Psychopathology
Jodi A. Quas and Ilona S. Yim and Tim F. Oberlander and David Nordstokke and Marilyn J. Essex and Jeffrey M. Armstrong and Nicole Bush and Jelena Obradovic and W. Thomas Boyce
DOI: 10.1017/s0954579414000480
06/2014

Evaluation of the Neurobehavioral Screening Tool in Children with Fetal Alcohol Spectrum Disorder (FASD)
Journal of Population Therapeutics and Clinical Pharmacology
PubMed: 24897061
05/2014

Rising antipsychotic prescriptions for children and youth: cross-sectoral solutions for a multimodal problem
Canadian Medical Association Journal
N. Di Pietro and J. Illes and for the Canadian Working Group on Antipsychotic Medications and Children
DOI: 10.1503/cmaj.131604
03/2014

The effect of perinatal exposures on the infant: Antidepressants and depression
Best Practice & Research Clinical Obstetrics & Gynaecology
Gillian E. Hanley and Tim F. Oberlander
DOI: 10.1016/j.bpobgyn.2013.09.001
01/2014

The impact of maternal positive and negative affect on fetal physiology and diurnal patterns.
The Israel journal of psychiatry and related sciences
Hanley GE and Rurak D and Lim K and Brain U and Oberlander TF
PubMed: 25372560
01/2014

Pain in Children with Autism
Mental Health and Pain
Tim F. Oberlander and Lonnie K. Zeltzer
DOI: 10.1007/978-2-8178-0414-9_12
2014

The symphonic structure of childhood stress reactivity: Patterns of sympathetic, parasympathetic, and adrenocortical responses to psychological challenge
Development and Psychopathology
Quas, J.A. and Yim, I.S. and Oberlander, T.F. and Nordstokke, D. and Essex, M.J. and Armstrong, J.M. and Bush, N. and Obradovi?, J. and Boyce, W.T.
DOI: 10.1017/S0954579414000480
2014

Evaluation of the neurobehavioral screening tool in children with fetal alcohol spectrum disorders (FASD)
Journal of Population Therapeutics and Clinical Pharmacology
LaFrance, M.-A. and McLachlan, K. and Nash, K. and Andrew, G. and Loock, C. and Oberlander, T.F. and Koren, G. and Rasmussen, C.
2014

The impact of maternal positive and negative affect on fetal physiology and diurnal patterns
Israel Journal of Psychiatry and Related Sciences
Hanley, G.E. and Rurak, D. and Lim, K. and Brain, U. and Oberlander, T.F.
2014

Neonatal pain and COMT Val158Met genotype in relation to serotonin transporter (SLC6A4) promoter methylation in very preterm children at school age
Frontiers in Behavioral Neuroscience
Cecil M. Y. Chau and Manon Ranger and Dian Sulistyoningrum and Angela M. Devlin and Tim F. Oberlander and Ruth E. Grunau
DOI: 10.3389/fnbeh.2014.00409
2014

Maternal and Fetal Factors That Influence Prenatal Exposure to Selective Serotonin Reuptake Inhibitor Antidepressants
Psychopharmacology and Pregnancy
DOI: 10.1007/978-3-642-54562-7_4
2014

Biomarkers of pain: physiological indices of pain reactivity in infants and children
Oxford Medicine Online
Susanne Brummelte and Tim F. Oberlander and Kenneth D. Craig
DOI: 10.1093/med/9780199642656.003.0038
11/2013

Infant developmental outcomes following prenatal exposure to antidepressants, and maternal depressed mood and positive affect
Early Human Development
Gillian E. Hanley and Ursula Brain and Tim F. Oberlander
DOI: 10.1016/j.earlhumdev.2012.12.012
08/2013

FACTORS IMPACTING DECISIONS TO DECLINE OR ADHERE TO ANTIDEPRESSANT MEDICATION IN PERINATAL WOMEN WITH MOOD AND ANXIETY DISORDERS
Depression and Anxiety
Shaila Misri and Andrea B. Eng and Jasmin Abizadeh and Ekin Blackwell and Alicia Spidel and Tim F. Oberlander
DOI: 10.1002/da.22137
06/2013

Pain in Children with Disabilities
Encyclopedia of Pain
Kenneth D. Craig and Tim F. Oberlander
DOI: 10.1007/978-3-642-28753-4_3090
2013

The impact of prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and maternal mood on mother-infant interactions at 3 months of age
Infant Behavior and Development
Weikum, W.M. and Mayes, L.C. and Grunau, R.E. and Brain, U. and Oberlander, T.F.
DOI: 10.1016/j.infbeh.2013.04.001
2013

Intervention Minimizing Preterm Infants' Exposure to NICU Light and Noise
Clinical Nursing Research
Aita, M. and Johnston, C. and Goulet, C. and Oberlander, T.F. and Snider, L.
DOI: 10.1177/1054773812469223
2013

Antidepressant use during pregnancy and serotonin transporter genotype (SLC6A4) Affect newborn serum reelin levels
Developmental Psychobiology
Brummelte, S. and Galea, L.A.M. and Devlin, A.M. and Oberlander, T.F.
DOI: 10.1002/dev.21056
2013

Physician variability in treating pain and irritability of unknown origin in children with severe neurological Impairment
Pain Research and Management
Siden, H.B. and Carleton, B.C. and Oberlander, T.F.
DOI: 10.1155/2013/193937
2013

Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age
Frontiers in Cellular Neuroscience
Weikum, W.M. and Brain, U. and Chau, C.M.Y. and Grunau, R.E. and Boyce, W.T. and Diamond, A. and Oberlander, T.F.
DOI: 10.3389/fncel.2013.00180
2013

Pain in Children with Disabilities
Encyclopedia of Pain
Kenneth D. Craig and Tim F. Oberlander
DOI: 10.1007/978-3-540-29805-2_3090
2013

Reply to Klinger et al
Birth Defects Research Part A: Clinical and Molecular Teratology
Gillian E. Hanley and Tim F. Oberlander
DOI: 10.1002/bdra.23095
11/2012

Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception
Proceedings of the National Academy of Sciences
W. M. Weikum and T. F. Oberlander and T. K. Hensch and J. F. Werker
DOI: 10.1073/pnas.1121263109
10/2012

Fetal Serotonin Reuptake Inhibitor Antidepressant Exposure: Maternal and Fetal Factors
The Canadian Journal of Psychiatry
Alison K Shea and Tim F Oberlander and Dan Rurak
DOI: 10.1177/070674371205700902
09/2012

A Tale of 2s: Optimizing Maternal—Child Health in the Context of Antenatal Maternal Depression and Antidepressant Use
The Canadian Journal of Psychiatry
Tim F Oberlander and Katherine L Wisner
DOI: 10.1177/070674371205700901
09/2012

Fetal Serotonin Signaling: Setting Pathways for Early Childhood Development and Behavior
Journal of Adolescent Health
Tim F. Oberlander
DOI: 10.1016/j.jadohealth.2012.04.009
08/2012

Third trimester fetal pulmonary artery Doppler blood flow velocity characteristics following prenatal selective serotonin reuptake inhibitor (SSRI) exposure
Early Human Development
Ken Lim and Ari Sanders and Ursula Brain and Wayne Riggs and Tim F. Oberlander and Dan Rurak
DOI: 10.1016/j.earlhumdev.2012.01.004
08/2012

Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function
Psychoneuroendocrinology
Jodi L. Pawluski and Ursula M. Brain and Caroline M. Underhill and Geoffrey L. Hammond and Tim F. Oberlander
DOI: 10.1016/j.psyneuen.2011.11.011
07/2012

Neurodevelopmental outcomes following prenatal exposure to serotonin reuptake inhibitor antidepressants: A “social teratogen” or moderator of developmental risk?
Birth Defects Research Part A: Clinical and Molecular Teratology
Gillian E. Hanley and Tim F. Oberlander
DOI: 10.1002/bdra.23032
06/2012

Biopsychosocial determinants of treatment outcome for mood and anxiety disorders up to 8 months postpartum
Archives of Women's Mental Health
Shaila Misri and Gillian Albert and Jasmin Abizadeh and Kristin Kendrick and Diana Carter and Deirdre Ryan and Tim F. Oberlander
DOI: 10.1007/s00737-012-0288-9
06/2012

Afternoon Cortisol in Elementary School Classrooms: Associations with Peer and Teacher Support and Child Behavior
School Mental Health
Nicole L. A. Catherine and Kimberly A. Schonert-Reichl and Clyde Hertzman and Tim F. Oberlander
DOI: 10.1007/s12310-012-9076-y
05/2012

The Management of Depression During Pregnancy: A Report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists
FOCUS
Kimberly A. Yonkers and Katherine L. Wisner and Donna E. Stewart and Tim F. Oberlander and Diana L. Dell and Nada Stotland and Susan Ramin and Linda Chaudron and Charles Lockwood
DOI: 10.1176/appi.focus.10.1.78
01/2012

Pediatric Analgesic Clinical Trial Designs, Measures, and Extrapolation: Report of an FDA Scientific Workshop
PEDIATRICS
C. B. Berde and G. A. Walco and E. J. Krane and K. J. S. Anand and J. V. Aranda and K. D. Craig and C. D. Dampier and J. C. Finkel and M. Grabois and C. Johnston and J. Lantos and A. Lebel and L. G. Maxwell and P. McGrath and T. F. Oberlander and L. E. Schanberg and B. Stevens and A. Taddio and C. L. von Baeyer and M. Yaster and W. T. Zempsky
DOI: 10.1542/peds.2010-3591
01/2012

Frontal EEG/ERP correlates of attentional processes, cortisol and motivational states in adolescents from lower and higher socioeconomic status
Frontiers in Human Neuroscience
Amedeo D'Angiulli and Joanne Weinberg and Tim F. Oberlander and Ruth E. Grunau and Clyde Hertzman and Stefania Maggi
DOI: 10.3389/fnhum.2012.00306
2012

Focused attention, heart rate deceleration, and cognitive development in preterm and full-term infants
Developmental Psychobiology
Petrie Thomas, J.H. and Whitfield, M.F. and Oberlander, T.F. and Synnes, A.R. and Grunau, R.E.
DOI: 10.1002/dev.20597
2012

Frontal EEG/ERP correlates of attentional processes, cortisol and motivational states in adolescents from lower and higher socioeconomic status
Frontiers in Human Neuroscience
D'Angiulli, A. and Van Roon, P.M. and Weinberg, J. and Oberlander, T.F. and Grunau, R.E. and Hertzman, C. and Maggi, S.
2012

Antidepressant use in children and adolescents: Practice touch points to guide paediatricians
Paediatrics & Child Health
Tim F Oberlander and Anton R Miller
DOI: 10.1093/pch/16.9.549
11/2011

Does breastfeeding reduce acute procedural pain in preterm infants in the neonatal intensive care unit? A randomized clinical trial
Pain
Liisa Holsti and Timothy F. Oberlander and Rollin Brant
DOI: 10.1016/j.pain.2011.07.022
11/2011

Third Trimester Fetal Heart Rate and Doppler Middle Cerebral Artery Blood Flow Velocity Characteristics During Prenatal Selective Serotonin Reuptake Inhibitor Exposure
Pediatric Research
Dan Rurak and Ken Lim and Ari Sanders and Ursula Brain and Wayne Riggs and Tim F Oberlander
DOI: 10.1203/pdr.0b013e31821ba11a
07/2011

Reply
Acta Psychiatrica Scandinavica
Warburton, W. and Hertzman, C. and Oberlander, T.F.
DOI: 10.1111/j.1600-0447.2010.01643.x
2011

Third trimester fetal heart rate and doppler middle cerebral artery blood flow velocity characteristics during prenatal selective serotonin reuptake inhibitor exposure
Pediatric Research
Rurak, D. and Lim, K. and Sanders, A. and Brain, U. and Riggs, W. and Oberlander, T.F.
DOI: 10.1203/PDR.0b013e31821ba11a
2011

Pain in Individuals with Intellectual Disabilities
Clinical Pain Management
Tim F. Oberlander and Chantel C. Burkitt and Frank J. Symons
DOI: 10.1002/9781444329711.ch39
11/2010

Prenatal Exposure to Maternal Depressed Mood and the MTHFR C677T Variant Affect SLC6A4 Methylation in Infants at Birth
PLoS ONE
Angela M. Devlin and Ursula Brain and Jehannine Austin and Tim F. Oberlander
DOI: 10.1371/journal.pone.0012201
08/2010

Cortisol, Behavior, and Heart Rate Reactivity to Immunization Pain at 4 Months Corrected Age in Infants Born Very Preterm
The Clinical Journal of Pain
Ruth E. Grunau and Mai Thanh Tu and Michael F. Whitfield and Tim F. Oberlander and Joanne Weinberg and Wayne Yu and Paul Thiessen and Gisela Gosse and David Scheifele
DOI: 10.1097/ajp.0b013e3181e5bb00
07/2010

Prenatal Effects of Selective Serotonin Reuptake Inhibitor Antidepressants, Serotonin Transporter Promoter Genotype (SLC6A4), and Maternal Mood on Child Behavior at 3 Years of Age
Archives of Pediatrics & Adolescent Medicine
Tim F. Oberlander and Michael Papsdorf and Ursula M. Brain and Shaila Misri and Colin Ross and Ruth E. Grunau
DOI: 10.1001/archpediatrics.2010.51
05/2010

Physiological correlates of memory recall in infancy: Vagal tone, cortisol, and imitation in preterm and full-term infants at 6 months
Infant Behavior and Development
David W. Haley and Ruth E. Grunau and Joanne Weinberg and Adi Keidar and Tim F. Oberlander
DOI: 10.1016/j.infbeh.2009.10.007
04/2010

Prenatal Alcohol Exposure Alters Biobehavioral Reactivity to Pain in Newborns
Alcoholism: Clinical and Experimental Research
Tim F. Oberlander and Sandra W. Jacobson and Joanne Weinberg and Ruth E. Grunau and Christopher D. Molteno and Joseph L. Jacobson
DOI: 10.1111/j.1530-0277.2009.01137.x
04/2010

Antenatal Depression and Anxiety Affect Postpartum Parenting Stress: A Longitudinal, Prospective Study
The Canadian Journal of Psychiatry
Shaila Misri and Kristin Kendrick and Tim F Oberlander and Sandhaya Norris and Lianne Tomfohr and Hongbin Zhang and Ruth E Grunau
DOI: 10.1177/070674371005500405
04/2010

Cortisol, behavior, and heart rate reactivity to immunization pain at 4 months corrected age in infants born very preterm
Clinical Journal of Pain
Grunau, R.E. and Tu, M.T. and Whitfield, M.F. and Oberlander, T.F. and Weinberg, J. and Yu, W. and Thiessen, P. and Gosse, G. and Scheifele, D.
DOI: 10.1097/AJP.0b013e3181e5bb00
2010

A register study of the impact of stopping third trimester selective serotonin reuptake inhibitor exposure on neonatal health
Acta Psychiatrica Scandinavica
Warburton, W. and Hertzman, C. and Oberlander, T.F.
DOI: 10.1111/j.1600-0447.2009.01490.x
2010

Sustained Neurobehavioral Effects of Exposure to SSRI Antidepressants During Development: Molecular to Clinical Evidence
Clinical Pharmacology & Therapeutics
T F Oberlander and J A Gingrich and M S Ansorge
DOI: 10.1038/clpt.2009.201
11/2009

The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists
General Hospital Psychiatry
Kimberly A. Yonkers and Katherine L. Wisner and Donna E. Stewart and Tim F. Oberlander and Diana L. Dell and Nada Stotland and Susan Ramin and Linda Chaudron and Charles Lockwood
DOI: 10.1016/j.genhosppsych.2009.04.003
09/2009

Neonatal S100B Protein Levels After Prenatal Exposure to Selective Serotonin Reuptake Inhibitors
PEDIATRICS
J. L. Pawluski and L. A.M. Galea and U. Brain and M. Papsdorf and T. F. Oberlander
DOI: 10.1542/peds.2009-0442
09/2009

Caregiving behavior and interactions of prenatally depressed mothers (antidepressant-treated and non-antidepressant-treated) during newborn acute pain
Infant Mental Health Journal
Fay F. Warnock and Roger Bakeman and Kim Shearer and Shaila Misri and Tim Oberlander
DOI: 10.1002/imhj.20220
07/2009

Depression during pregnancy: the potential impact of increased risk for fetal aneuploidy on maternal mood
Clinical Genetics
C Hippman and TF Oberlander and WG Honer and S Misri and JC Austin
DOI: 10.1111/j.1399-0004.2008.01056.x
01/2009

Optimizing neurodevelopmental outcomes in infants and children following prenatal SSRI exposure
Pediatric Health
Tim F Oberlander
DOI: 10.2217/phe.09.56
2009

The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists.
Obstetrics and gynecology
Yonkers, K.A. and Wisner, K.L. and Stewart, D.E. and Oberlander, T.F. and Dell, D.L. and Stotland, N. and Ramin, S. and Chaudron, L. and Lockwood, C.
DOI: 10.1097/AOG.0b013e3181ba0632
2009

Pain in individuals with intellectual and developmental disabilities
Journal of Pain Management
Symons, F.J. and Oberlander, T.F. and Kehl, L.J.
2009

Contingency Learning and Reactivity in Preterm and Full-Term Infants at 3 Months
Infancy
David W. Haley and Ruth E. Grunau and Tim F. Oberlander and Joanne Weinberg
DOI: 10.1080/15250000802458682
11/2008

Effects of intra-oral sucrose on crying, mouthing and hand-mouth contact in newborn and six-week-old infants.
Developmental Medicine & Child Neurology
DOI: 10.1111/j.1469-8749.1994.tb11898.x
11/2008

Hypothalamic–pituitary–adrenal (HPA) axis function in 3-month old infants with prenatal selective serotonin reuptake inhibitor (SSRI) antidepressant exposure
Early Human Development
Tim F. Oberlander and Ruth Grunau and Linda Mayes and Wayne Riggs and Dan Rurak and Michael Papsdorf and Shaila Misri and Joanne Weinberg
DOI: 10.1016/j.earlhumdev.2008.06.008
10/2008

Effects of timing and duration of gestational exposure to serotonin reuptake inhibitor antidepressants: Population-based study
British Journal of Psychiatry
Tim F. Oberlander and William Warburton and Shaila Misri and Jaafar Aghajanian and Clyde Hertzman
DOI: 10.1192/bjp.bp.107.037101
05/2008

Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
Epigenetics
Tim F. Oberlander and Joanne Weinberg and Michael Papsdorf and Ruth Grunau and Shaila Misri and Angela M. Devlin
DOI: 10.4161/epi.3.2.6034
03/2008

Is It Painful or Not?
The Clinical Journal of Pain
Liisa Holsti and Ruth E. Grunau and Tim F. Oberlander and Horacio Osiovich
DOI: 10.1097/ajp.0b013e318158c5e5
01/2008

Pain Management for Children with a Developmental Disability in a Primary Care Setting
Pain in Children
Harold (Hal) Siden and Tim F. Oberlander
DOI: 10.1007/978-1-59745-476-6_4
2008

Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications
Molecular Psychiatry
Oberlander, T.F. and Bonaguro, R.J. and Misri, S. and Papsdorf, M. and Ross, C.J.D. and Simpson, E.M.
DOI: 10.1038/sj.mp.4002007
2008

Major congenital malformations following prenatal exposure to serotonin reuptake inhibitors and benzodiazepines using population-based health data
Birth Defects Research Part B - Developmental and Reproductive Toxicology
Oberlander, T.F. and Warburton, W. and Misri, S. and Riggs, W. and Aghajanian, J. and Hertzman, C.
DOI: 10.1002/bdrb.20144
2008

Is it painful or not? Discriminant validity of the Behavioral Indicators of Infant Pain (BIIP) scale
Clinical Journal of Pain
Holsti, L. and Grunau, R.E. and Oberlander, T.F. and Osiovich, H.
DOI: 10.1097/AJP.0b013e318158c5e5
2008

Neonatal Risks of Maternal Treatment With Mood Stabilizers—Reply
Archives of General Psychiatry
Tim F. Oberlander and William Warburton and Shaila Misri and Jaafar Aghajanian and Clyde Hertzman
DOI: 10.1001/archpsyc.64.7.867
07/2007

Toward comprehensive treatment for postpartum depressed mothers and their infants
BC Medical Journal
04/2007

‘Beliefs about pain among professionals working with children with significant neurologic impairment’
Developmental Medicine & Child Neurology
Tim F Oberlander and Maureen E O‘Donnell
DOI: 10.1111/j.1469-8749.2001.tb00734.x
02/2007

Biobehavioural reactivity to pain in preterm infants: a marker of neuromotor development
Developmental Medicine & Child Neurology
Ruth E Grunau and Michael F Whitfield and Taryn Fay and Liisa Holsti and Timothy Oberlander and Marilynn L Rogers
DOI: 10.1111/j.1469-8749.2006.tb01298.x
02/2007

Cytochrome P4502D6 (CYP2D6) Gene Locus Heterogeneity: Characterization of Gene Duplication Events
Clinical Pharmacology & Therapeutics
A Gaedigk and L Ndjountché and K Divakaran and L DiAnne Bradford and I Zineh and T F Oberlander and D C Brousseau and D G McCarver and J A Johnson and S W Alander and K Wayne Riggs and J Steven Leeder
DOI: 10.1038/sj.clpt.6100033
02/2007

Externalizing and Attentional Behaviors in Children of Depressed Mothers Treated With a Selective Serotonin Reuptake Inhibitor Antidepressant During Pregnancy
Archives of Pediatrics & Adolescent Medicine
Tim F. Oberlander and Pratibha Reebye and Shaila Misri and Michael Papsdorf and John Kim and Ruth E. Grunau
DOI: 10.1001/archpedi.161.1.22
01/2007

Toward comprehensive treatment for postpartum depressed mothers and their infants
British Columbia Medical Journal
Lansky, P.S. and Oberlander, T.
2007

Behavioral Responses to Pain Are Heightened After Clustered Care in Preterm Infants Born Between 30 and 32 Weeks Gestational Age
The Clinical Journal of Pain
Liisa Holsti and Ruth E. Grunau and Michael F. Whifield and Tim F. Oberlander and Viveca Lindh
DOI: 10.1097/01.ajp.0000210921.10912.47
11/2006

A Prospective Controlled Study of Neurodevelopment in HIV-Uninfected Children Exposed to Combination Antiretroviral Drugs in Pregnancy
PEDIATRICS
A. Alimenti and J. C. Forbes and T. F. Oberlander and D. M. Money and R. E. Grunau and M. P. Papsdorf and E. Maan and L. J. Cole and D. R. Burdge
DOI: 10.1542/peds.2006-0525
10/2006

Biobehavioural reactivity to pain in preterm infants: A marker of neuromotor development
Acute Pain
R.E. Grunau and M.F. Whitfield and T. Fay and L. Holsti and T. Oberlander and M.L. Rogers
DOI: 10.1016/j.acpain.2006.08.033
10/2006

Neonatal Outcomes After Prenatal Exposure to Selective Serotonin Reuptake Inhibitor Antidepressants and Maternal Depression Using Population-Based Linked Health Data
Archives of General Psychiatry
Tim F. Oberlander and William Warburton and Shaila Misri and Jaafar Aghajanian and Clyde Hertzman
DOI: 10.1001/archpsyc.63.8.898
08/2006

Internalizing Behaviors in 4-Year-Old Children Exposed in Utero to Psychotropic Medications
American Journal of Psychiatry
Shaila Misri and Pratibha Reebye and Kristin Kendrick and Diana Carter and Deirdre Ryan and Ruth E. Grunau and Tim F. Oberlander
DOI: 10.1176/ajp.2006.163.6.1026
06/2006

Summary Proceedings From the Neonatal Pain-Control Group
Pediatrics
Kanwaljeet J.S. Anand and Jacob V. Aranda and Charles B. Berde and ShaAvhrée Buckman and Edmund V. Capparelli and Waldemar Carlo and Patricia Hummel and C. Celeste Johnston and John Lantos and Victoria Tutag-Lehr and Anne M. Lynn and Lynne G. Maxwell and Tim F. Oberlander and Tonse N.K. Raju and Sulpicio G. Soriano and Anna Taddio and Gary A. Walco
DOI: 10.1542/peds.2005-0620c
03/2006

Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast-feeding
British Journal of Clinical Pharmacology
John Kim and K. Wayne Riggs and Shaila Misri and Nancy Kent and Tim F. Oberlander and Ruth E. Grunau and Colleen Fitzgerald and Dan W. Rurak
DOI: 10.1111/j.1365-2125.2005.02538.x
02/2006

Biobehavioural reactivity to pain in preterm infants: A marker of neuromotor development
Developmental Medicine and Child Neurology
Grunau, R.E. and Whitfield, M.F. and Fay, T. and Holsti, L. and Oberlander, T. and Rogers, M.L.
DOI: 10.1017/S0012162206001010
2006

Summary proceedings from the neonatal pain-control group
Pediatrics
Anand, K.J.S. and Aranda, J.V. and Berde, C.B. and Buckman, S. and Capparelli, E.V. and Carlo, W. and Hummel, P. and Johnston, C.C. and Lantos, J. and Tutag-Lehr, V. and Lynn, A.M. and Maxwell, L.G. and Oberlander, T.F. and Raju, T.N.K. and Soriano, S.G. and Taddio, A. and Walco, G.A.
DOI: 10.1542/peds.2005-0620C
2006

Body Movements: An Important Additional Factor in Discriminating Pain From Stress in Preterm Infants
The Clinical Journal of Pain
Liisa Holsti and Ruth E Grunau and Tim F Oberlander and Michael F Whitfield and Joanne Weinberg
DOI: 10.1097/01.ajp.0000146163.30776.44
11/2005

Analgesia and local anesthesia during invasive procedures in the neonate
Clinical Therapeutics
K.J.S. Anand and C. Celeste^Johnston and Tim F. Oberlander and Anna Taddio and Victoria Tutag Lehr and Gary A. Walco
DOI: 10.1016/j.clinthera.2005.06.018
06/2005

Prior pain induces heightened motor responses during clustered care in preterm infants in the NICU
Early Human Development
Liisa Holsti and Ruth E. Grunau and Tim F. Oberlander and Michael F. Whitfield
DOI: 10.1016/j.earlhumdev.2004.08.002
03/2005

Neonatal procedural pain exposure predicts lower cortisol and behavioral reactivity in preterm infants in the NICU
Pain
Ruth E. Grunau and Liisa Holsti and David W. Haley and Tim Oberlander and Joanne Weinberg and Alfonso Solimano and Michael F. Whitfield and Colleen Fitzgerald and Wayne Yu
DOI: 10.1016/j.pain.2004.10.020
02/2005

Pain Reactivity in 2-Month-Old Infants After Prenatal and Postnatal Serotonin Reuptake Inhibitor Medication Exposure
PEDIATRICS
T. F. Oberlander
DOI: 10.1542/peds.2004-0420
02/2005

Analgesia and anesthesia for neonates: Study design and ethical issues
Clinical Therapeutics
DOI: 10.1016/j.clinthera.2005.06.021
2005

Relation between Prenatal Maternal Mood and Anxiety and Neonatal Health
The Canadian Journal of Psychiatry
Shaila Misri and Tim F Oberlander and Nichole Fairbrother and Diana Carter and Deirdre Ryan and Annie J Kuan and Pratibha Reebye
DOI: 10.1177/070674370404901006
10/2004

Specific Newborn Individualized Developmental Care and Assessment Program Movements Are Associated With Acute Pain in Preterm Infants in the Neonatal Intensive Care Unit
PEDIATRICS
L. Holsti
DOI: 10.1542/peds.114.1.65
07/2004

Expression of Pain in Children With Autism
The Clinical Journal of Pain
Rami Nader and Tim F. Oberlander and Christine T. Chambers and Kenneth D. Craig
DOI: 10.1097/00002508-200403000-00005
03/2004

Does Prone or Supine Position Influence Pain Responses in Preterm Infants at 32 Weeks Gestational Age?
The Clinical Journal of Pain
Ruth Eckstein Grunau and Maria Beatriz Martins Linhares and Liisa Holsti and Tim F. Oberlander and Michael F. Whitfield
DOI: 10.1097/00002508-200403000-00003
03/2004

Pharmacologic Factors Associated With Transient Neonatal Symptoms Following Prenatal Psychotropic Medication Exposure
The Journal of Clinical Psychiatry
Tim F. Oberlander and Shaila Misri and Colleen E. Fitzgerald and Xanthoula Kostaras and Dan Rurak and Wayne Riggs
DOI: 10.4088/jcp.v65n0214
02/2004

Pharmacologic factors associated with transient neonatal symptoms following prenatal psychotropic medication exposure
Journal of Clinical Psychiatry
Oberlander, T.F. and Misri, S. and Fitzgerald, C.E. and Kostaras, X. and Rurak, D. and Riggs, W.
DOI: 10.4088/JCP.v65n0214
2004

Are there developmentally distinct motor indicators of pain in preterm infants?
Early Human Development
Sara J Morison and Liisa Holsti and Ruth Eckstein Grunau and Michael F Whitfield and Tim F Oberlander and Herbert W.P Chan and Linda Williams
DOI: 10.1016/s0378-3782(03)00044-6
06/2003

Are there developmentally distinct motor indicators of pain in preterm infants?
Early Human Development
Morison, S.J. and Holsti, L. and Grunau, R.E. and Whitfield, M.F. and Oberlander, T.F. and Chan, H.W.P. and Williams, L.
DOI: 10.1016/S0378-3782(03)00044-6
2003

Methodological considerations for the use of heart rate variability as a measure of pain reactivity in vulnerable infants
Clinics in Perinatology
Tim Oberlander and J.Philip Saul
DOI: 10.1016/s0095-5108(02)00013-1
09/2002

Does Parenchymal Brain Injury Affect Biobehavioral Pain Responses in Very Low Birth Weight Infants at 32 Weeks' Postconceptional Age?
PEDIATRICS
T. F. Oberlander and R. E. Grunau and C. Fitzgerald and M. F. Whitfield
DOI: 10.1542/peds.110.3.570
09/2002

Prolonged Prenatal Psychotropic Medication Exposure Alters Neonatal Acute Pain Response
Pediatric Research
Tim F Oberlander and Ruth Eckstein Grunau and Colleen Fitzgerald and Ann-Louise Ellwood and Shaila Misri and Dan Rurak and Kenneth Wayne Riggs
DOI: 10.1203/00006450-200204000-00008
04/2002

Methodological considerations for the use of heart rate variability as a measure of pain reactivity in vulnerable infants
Clinics in Perinatology
Oberlander, T. and Saul, J.Philip
DOI: 10.1016/S0095-5108(02)00013-1
2002

Prevention in adulthood: Forging a doctor-patient partnership
Primary Care - Clinics in Office Practice
Oberlander, T. and Saul, J.Philip
DOI: 10.1016/S0095-4543(02)00018-0
2002

Pain Assessment and Management in Infants and Young Children with Developmental Disabilities
Infants & Young Children
Tim F. Oberlander
DOI: 10.1097/00001163-200114020-00006
10/2001

Demographic and Therapeutic Determinants of Pain Reactivity in Very Low Birth Weight Neonates at 32 Weeks' Postconceptional Age
PEDIATRICS
R. E. Grunau and T. F. Oberlander and M. F. Whitfield and C. Fitzgerald and S. K. Lee
DOI: 10.1542/peds.107.1.105
01/2001

Pain reactivity in former extremely low birth weight infants at corrected age 8 months compared with term born controls
Infant Behavior and Development
Ruth Eckstein Grunau and Tim F. Oberlander and Michael F. Whitfield and Colleen Fitzgerald and Sara J. Morison and J. Philip Saul
DOI: 10.1016/s0163-6383(01)00065-0
01/2001

Relations Between Behavioral and Cardiac Autonomic Reactivity to Acute Pain in Preterm Neonates
The Clinical Journal of Pain
Sara J. Morison and Ruth E. Grunau and Tim F. Oberlander and Michael F. Whitfield
DOI: 10.1097/00002508-200112000-00010
2001

Beliefs about pain among professionals working with children with significant neurologic impairment
Developmental Medicine and Child Neurology
Oberlander, T.F. and O'Donnell, M.E.
DOI: 10.1017/S0012162201230254
2001

Pain reactivity in former extremely low birth weight infants at corrected age 8 months compared with term born controls
Infant Behavior and Development
Eckstein Grunau, R. and Oberlander, T.F. and Whitfield, M.F. and Fitzgerald, C. and Morison, S.J. and Philip Saul, J.
DOI: 10.1016/S0163-6383(01)00065-0
2001

Prenatal and Breast Milk Morphine Exposure Following Maternal Intrathecal Morphine Treatment
Journal of Human Lactation
Tim F. Oberlander and Paula Robeson and Val Ward and R. Stuart Huckin and A. Kamani and Arthur Harpur and William McDonald
DOI: 10.1177/089033440001600210
05/2000

Biobehavioral Pain Responses in Former Extremely Low Birth Weight Infants at Four Months' Corrected Age
Pediatrics
Tim F. Oberlander and Ruth Eckstein Grunau and Michael F. Whitfield and Colleen Fitzgerald and Sandy Pitfield and J. Philip Saul
DOI: 10.1542/peds.105.1.e6
01/2000

Evaluating Treatment Outcome in an Interdisciplinary Pediatric Pain Service
Pain Research and Management
Susan M Bennett and Christine T Chambers and Doria Bellows and Colleen A Court and Elizabeth Huntsman and Carolyne Montgomery and Tim F Oberlander and Michelle Sheriff and Harold Siden
DOI: 10.1155/2000/767058
2000

Biobehavioral pain responses in former extremely low birth weight infants at four months' corrected age
Pediatrics
Oberlander, T.F. and Grunau, R.E. and Whitfield, M.F. and Fitzgerald, C. and Pitfield, S. and Philip Saul, J.
2000

Pain Management of Junctional Epidermolysis Bullosa in an 11-Year-Old Boy
Pediatric Dermatology
Yao-Kun Chiu and Julie S. Prendiville and Susan M. Bennett and Carolyne J. Montgomery and Tim F. Oberlander
DOI: 10.1046/j.1525-1470.1999.00120.x
11/1999

Biobehavioral Responses to Acute Pain in Adolescents with a Significant Neurologic Impairment
The Clinical Journal of Pain
Tim F. Oberlander and Cheryl A. Gilbert and Christine T. Chambers and Maureen E. O'Donnell and Kenneth D. Craig
DOI: 10.1097/00002508-199909000-00007
09/1999

Pain in Children with Significant Neurological Impairment
Journal of Developmental & Behavioral Pediatrics
TIM F. OBERLANDER and MAUREEN E. O'DONNELL and CAROLYNE J. MONTGOMERY
DOI: 10.1097/00004703-199908000-00006
08/1999

The Developmental Character of Cardiac Autonomic Responses to an Acute Noxious Event in 4- and 8-Month-Old Healthy Infants
Pediatric Research
Tim F Oberlander and Ruth Eckstein Grunau and Sandy Pitfield and Michael F Whitfield and J Philip Saul
DOI: 10.1203/00006450-199904010-00011
04/1999

The developmental character of cardiac autonomic responses to an acute noxious event in 4-and 8-month-old healthy infants
Pediatric Research
Oberlander, T.F. and Grunau, R.E. and Pitfield, S. and Whitfield, M.F. and Saul, J.P.
1999

Bedside application of the Neonatal Facial Coding System in pain assessment of premature infants
Pain
Ruth Eckstein Grunau and Tim Oberlander and Liisa Holsti and Michael F. Whitfield
DOI: 10.1016/s0304-3959(98)00046-3
06/1998

Bedside application of the neonatal facial coding system in pain assessment of premature neonates
Pain
Grunau, R.E. and Oberlander, T. and Holsti, L. and Whitfield, M.F.
DOI: 10.1016/S0304-3959(98)00046-3
1998

Cardiac Autonomic and Behavioral Responses to Acute Pain in 4 Month Old Infants † 80
Pediatric Research
Tim F. Oberlander and Ruth V.E. Grunau and Micheal F. Whitfield and J. Philip Saul
DOI: 10.1203/00006450-199704001-00101
04/1997

Developmental character and long-term consequences of pain in infants and children
Child and Adolescent Psychiatric Clinics of North America
Anand, Kanwaljeet and Grunau, Ruth and Oberlander, Tim
01/1997

Developmental character and long-term consequences of pain in infants and children
Child and Adolescent Psychiatric Clinics of North America
Anand, K.S. and Grunau, R.E. and Oberlander, T.F.
1997

Erratum: Halothane and cardiac autonomic control in infants: Assessment with quantitative respiratory sinus arrhythmia (Pediatric Research (1996) 40 (710-717))
Pediatric Research
Oberlander, T.F.
1997

Halothane and Cardiac Autonomic Control in Infants: Assessment with Quantitative Respiratory Sinus Arrhythmia
Pediatric Research
Tim F Oberlander and C B Berde and J Philip Saul
DOI: 10.1203/00006450-199611000-00010
11/1996

Time and frequency domain methods for heart rate variability analysis: A methodological comparison
Psychophysiology
DANIEL A. LITVACK and TIM F. OBERLANDER and LAUREL H. CARNEY and J. PHILIP SAUL
DOI: 10.1111/j.1469-8986.1995.tb02101.x
09/1995

Infants Tolerate Spinal Anesthesia with Minimal Overall Autonomic Changes
Anesthesia & Analgesia
Tim F. Oberlander and Charles B. Berde and Kar H. Lam and L. A. Rappaport and J. Philip Saul
DOI: 10.1097/00000539-199501000-00005
01/1995

Recurrent abdominal pain: evaluation and management
International Seminars in Paediatric Gastroenterology and Nutrition
1994

Recurrent Abdominal Pain During Childhood
Pediatrics in Review
T. F. Oberlander and L. A. Rappaport
DOI: 10.1542/pir.14-8-313
08/1993

Advice Seeking and Appropriate Use of a Pediatric Emergency Department
Archives of Pediatrics & Adolescent Medicine
T. F. Oberlander
DOI: 10.1001/archpedi.1993.02160320065021
08/1993

Short-term Effects of Feed Composition on Sleeping and Crying in Newborns
Pediatrics
Oberlander, Tim F. and Barr, Ronald G. and Young, Simon N. and Brian, Jessica A.
1992

Short-term effects of feed composition on sleeping and crying in newborns
Pediatrics
Oberlander, T.F. and Barr, R.G. and Young, S.N. and Brian, J.A.
1992

Research

Current Projects
My research extends from studies of child behaviour at the individual to population levels that seeks to understand how in utero exposure to maternal mood and selective serotonin reuptake inhibitor (SSRI) antidepressants sets pathways for both developmental risk and resiliency during early childhood. My work provides strong evidence that both influences have an impact on stress regulation and mood in childhood, possibly reflecting early changes in central serotonin (5HT) levels.

Increasingly my work is showing that the developing brain has a remarkable capacity for change, such that even in the face of adversity, some children do very well. The goal of my work is to figure out how and why this happens, and use these findings to identify opportunities for interventions that reduce risk. Emerging findings are beginning to point to ways that could possibly assist clinicians and families in understanding critical issues that influence a child’s emotional well-being and academic success later in school. As Project Lead for CFRI’s 3T MR Imaging facility I have the opportunity to advance studies of early brain development using advance imaging technology.

I have three main areas of research:

Developmental effects of prenatal psychotropic medication exposure – fetal, neonatal, infant and childhood outcomes: This research focuses on studies of the developmental impact of prenatal exposure to psychotropic medications (i.e. selective serotonin reuptake inhibitor [SSRI] antidepressants) and depressed maternal mood that extends from fetal periods to early adolescence. Biobehavioural, pharmacologic and genetic factors that moderate fetal exposure are studied. Outcomes of particular interest are pain/stress reactivity (neuroendocrine, heart variability), cognitive function (executive functions), attention threat bias, and measures of arousal and emotional regulation. This work also includes examination of the role of key genetic (i.e. SLC6A4) variations and epigenetic (i.e. methylation) factors that may also contribute to altered early serotonin levels.

Pharmacoepidemiology and Child Development: Since 2004 we have used population level health data linking antenatal maternal prescription records with birth/neonatal health records to distinguish the impact of maternal mood from in utero SSRI exposure. We have reported novel findings indicting that the effects of gestational maternal SSRI use differ from those of maternal mental illness and that neonatal outcomes vary with the timing and duration of prenatal SSRI exposure. Recently, we have started examining developmental and behavioural outcomes (learning, mood and autism spectrum disorder risk, ASD) related to in utero SSRI exposure, socioeconomic conditions and maternal mental health.

Pain and children with developmental disabilities: This research seeks to understand pain in children with developmental disabilities. The current focus of this work is to improve pain assessment management among this population of children.

Research Methodology
Fetal, neonatal and child behavioural state regulation
Non invasive stress measures (cardiac autonomic (RSA, PEP), salivary alpha-amylase & cortisol)
Integration of genetic and epigenetic factors to study interactions reflecting the impact of early experience
Population-based linked child health data

Grants

CIHR Operating Grant - Project: "Attention bias and executive functions in 9-14 year olds following prenatal antidepressant exposure" (2014-2019)

CIHR Operating Grant - Project: "Developmental origins of autism: A population level linked data study of prenatal antidepressant medication exposure" (2014-2017)

CIHR Operating Grant - Project: "Early child behavior: Relations to early brain development and maternal mood" (2012-2017)

Honours & Awards

Early Career UBC Scholar, The Peter Wall Institute for Advanced Studies, UBC (2003-2004)

Human Early Learning Partnership, Senior Scholar Award (2002-2005)

R. Howard Webster Professor in Early Childhood Development (2004-present)

Research Group Members

Ursula Brain, Research Manager, Healthy Starts Program
Dawna Brown, Research Assistant
Kayleigh Campbell, PhD Candidate
Efrat Czerniak, Volunteer
Sarah Hutchison, Sunny Hill Child Development and Rehabilitation Research Manager
Edlyn Lim, Research Librarian
Jessica Luu, Research Assistant Tech 2
Mandeep Mahal, Developmental Pediatrics Subspecialty Resident
Bianca Matthews, Summer Student - Research Assistant
Amanda Nitschke, Doctoral Student
Leora Pearl-Dowler, Summer student
Katie Rintoul, Research Assistant
Preety Salh, Developmental Pediatrician
Jane Shen, researcher
Marie-Noelle Wharton Cancio, Research Coordinator
Enav Zusman