Dina Panagiotopoulos
MD, FRCPC
Investigator, Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital
Pediatric Endocrinologist, BC Children's Hospital
The Journal of Clinical Endocrinology & Metabolism
Jana Palaniyandi and Jennifer E Bruin and Mandy Fisher and Michael M Borghese and Myriam P Hoyeck and Constadina Panagiotopoulos and Mireille Guay and Jillian Ashley-Martin
DOI: 10.1210/clinem/dgag01501 / 2026
The Journal of Clinical Endocrinology & Metabolism
Jana Palaniyandi and Jennifer E Bruin and Mandy Fisher and Michael M Borghese and Myriam P Hoyeck and Constadina Panagiotopoulos and Jillian Ashley-Martin
DOI: 10.1210/clinem/dgaf14311 / 2025
Annals of Epidemiology
Zhilin Wang and Christine Till and Meaghan Hall and Jana El Sabbagh and Gina Muckle and Jean Sguin and Linda Booij and Khrista Boylan and Constadina Panagiotopoulos and Katherine Morrison and Maryse Bouchard and Bruce Lanphear and Ashley J. Malin
DOI: 10.1016/j.annepidem.2025.08.00209 / 2025
BMJ open
Wiedeman AM and Panagiotopoulos C and Devlin AM
DOI: 10.1136/bmjopen-2024-093842 PubMed: 4094004909 / 2025
Environmental Research
Ashlyn Simpson and Mandy Fisher and Stphanie Harrison and Anne-Sophie Morisset and Michael M. Borghese and Joseph M. Braun and Maryse F. Bouchard and Trisha Saha and Constadina Panagiotopoulos and Linda Booij and Katherine Morrison and Jillian Ashley-Martin
DOI: 10.1016/j.envres.2025.12179008 / 2025
Pediatric Diabetes
Kristen Favel and Maryellen S. Kelly and Shing Tat Theodore Lam and Jeffrey N. Bone and Kathryn E. Morgan and Heidi A. Stephany and Sruthi Thomas and Kourosh Afshar and Constadina Panagiotopoulos and Andrea Scaramuzza
DOI: 10.1155/pedi/529483501 / 2025
Pediatric Diabetes
Kristen Favel and Cherry Mammen and Constadina Panagiotopoulos
DOI: 10.1155/2023/664892006 / 2023
OSF Registries
DOI: 10.17605/osf.io/kcxp2Canadian Journal of Diabetes
Kristen Favel and Mike Irvine and Rebecca Ronsley and Constadina Panagiotopoulos and Cherry Mammen
DOI: 10.1016/j.jcjd.2022.01.00707 / 2022
JMIR Research Protocols
Nancy Wu and Anne-Sophie Brazeau and Meranda Nakhla and Deborah Chan and Deborah Da Costa and Geetha Mukerji and Sonia Butalia and Daniele Pacaud and Mlanie Henderson and Constadina Panagiotopoulos and Elham Rahme and Kaberi Dasgupta
DOI: 10.2196/1871408 / 2020
Journal of Clinical Lipidology
Zoe White and Chady H. Hakim and Marine Theret and N. Nora Yang and Fabio Rossi and Dan Cox and Gordon A. Francis and Volker Straub and Kathryn Selby and Constadina Panagiotopoulos and Dongsheng Duan and Pascal Bernatchez
DOI: 10.1016/j.jacl.2020.05.09807 / 2020
Nancy Wu and Anne-Sophie Brazeau and Meranda Nakhla and Deborah Chan and Deborah Da Costa and Geetha Mukerji and Sonia Butalia and Daniele Pacaud and Mlanie Henderson and Constadina Panagiotopoulos and Elham Rahme and Kaberi Dasgupta
DOI: 10.2196/preprints.1871403 / 2020
Pediatric Diabetes
Sinead Glackin and Nazrul Islam and Amanda M. Henderson and Janis M. Dionne and Kevin C. Harris and Constadina Panagiotopoulos and Angela M. Devlin
DOI: 10.1111/pedi.1296003 / 2020
Journal of Medical Internet Research
Anne-Sophie Brazeau and Meranda Nakhla and Michael Wright and Mlanie Henderson and Constadina Panagiotopoulos and Daniele Pacaud and Patricia Kearns and Elham Rahme and Deborah Da Costa and Kaberi Dasgupta
DOI: 10.2196/jmir.943204 / 2018
Clinical Nutrition ESPEN
Mikaela K. Barker and Carly M. Sable and Sarah E. Montgomery and Lorrie Chow and Timothy J. Green and Constadina Panagiotopoulos and Angela M. Devlin
DOI: 10.1016/j.clnesp.2017.09.01302 / 2018
Anne-Sophie Brazeau and Meranda Nakhla and Michael Wright and Mlanie Henderson and Constadina Panagiotopoulos and Daniele Pacaud and Patricia Kearns and Elham Rahme and Deborah Da Costa and Kaberi Dasgupta
DOI: 10.2196/preprints.943211 / 2017
Pediatric Diabetes
Rebecca Ronsley and Nazrul Islam and Claire Ronsley and Daniel L Metzger and Constadina Panagiotopoulos
DOI: 10.1111/pedi.1255606 / 2017
JAMA Pediatrics
Brenden E. Hursh and Rebecca Ronsley and Nazrul Islam and Cherry Mammen and Constadina Panagiotopoulos
DOI: 10.1001/jamapediatrics.2017.002005 / 2017
BioMed Central
DOI: 10.14288/1.0347221JMIR Research Protocols
Anne-Sophie Brazeau and Meranda Nakhla and Michael Wright and Constadina Panagiotopoulos and Daniele Pacaud and Mlanie Henderson and Elham Rahme and Deborah Da Costa and Kaberi Dasgupta
DOI: 10.2196/resprot.662912 / 2016
Sellers EA and Hadjiyannakis S and Amed S and Dart AB and Dyck RF and Hamilton J and Langlois V and Panagiotopoulos C and Dean HJ
DOI: 10.1016/j.jpeds.2015.09.042 PubMed: 2647068810 / 2015
Pharmacogenomics Journal
Cote, A.T. and Panagiotopoulos, C. and Devlin, A.M.
DOI: 10.1038/tpj.2014.35Canadian Journal of Psychiatry
Ronsley, R. and Nguyen, D. and Davidson, J. and Panagiotopoulos, C.
Arteriosclerosis, Thrombosis, and Vascular Biology
Cote, A.T. and Phillips, A.A. and Harris, K.C. and Sandor, G.G.S. and Panagiotopoulos, C. and Devlin, A.M.
DOI: 10.1161/ATVBAHA.114.305062Journal of Pediatric Gastroenterology and Nutrition
Harel, S. and Hursh, B.E. and Chan, E.S. and Avinashi, V. and Panagiotopoulos, C.
DOI: 10.1097/MPG.0000000000000848Annals of Behavioral Medicine
Msse, L.C. and Watts, A.W. and Barr, S.I. and Tu, A.W. and Panagiotopoulos, C. and Geller, J. and Chanoine, J.-P.
DOI: 10.1007/s12160-014-9658-zAcademic Psychiatry
Gibson, J. and Nguyen, D. and Davidson, J. and Panagiotopoulos, C.
DOI: 10.1007/s40596-014-0177-9Pharmacogenomics
Devlin, A.M. and Panagiotopoulos, C.
DOI: 10.2217/pgs.15.55The Science and Ethics of Antipsychotic Use in Children
Rebecca Ronsley and Lorrie Chow and Kristine Kuss and Jana Davidson and Constadina Panagiotopoulos
DOI: 10.1016/b978-0-12-800016-8.00004-0Di Pietro N and Illes J and Canadian Working Group on Antipsychotic Medications and Children
DOI: 10.1503/cmaj.131604 PubMed: 2466465506 / 2014
Paediatrics & Child Health
Constadina Panagiotopoulos and Duc Nguyen and Jane Smith
DOI: 10.1093/pch/19.5.25605 / 2014
Panagiotopoulos C and Nguyen D and Smith J
PubMed: 2485542905 / 2014
Paediatrics & Child Health
Brenden E Hursh and Alysha Dedhar and Constadina Panagiotopoulos
DOI: 10.1093/pch/19.5.233-b05 / 2014
Hursh BE and Dedhar A and Panagiotopoulos C
PubMed: 2485542205 / 2014
Journal of Clinical Psychopharmacology
Ngai, Y.F. and Sabatini, P. and Nguyen, D. and Davidson, J. and Chanoine, J.-P. and Devlin, A.M. and Lynn, F.C. and Panagiotopoulos, C.
DOI: 10.1097/JCP.0000000000000118Pediatric Exercise Science
Cote, A.T. and Devlin, A.M. and Panagiotopoulos, C.
DOI: 10.1123/pes.2014-0076Ronsley R and Scott D and Warburton WP and Hamdi RD and Louie DC and Davidson J and Panagiotopoulos C
PubMed: 2376826406 / 2013
Journal of School Health
Ronsley, R. and Lee, A.S. and Kuzeljevic, B. and Panagiotopoulos, C.
DOI: 10.1111/josh.12072Canadian Journal of Diabetes
Panagiotopoulos, C. and Riddell, M.C. and Sellers, E.A.C.
DOI: 10.1016/j.jcjd.2013.07.039Canadian Journal of Psychiatry
Ronsley, R. and Scott, D. and Warburton, W.P. and Hamdi, R.D. and Louie, D.C. and Davidson, J. and Panagiotopoulos, C.
Journal of the American College of Cardiology
Cote, A.T. and Harris, K.C. and Panagiotopoulos, C. and Sandor, G.G.S. and Devlin, A.M.
DOI: 10.1016/j.jacc.2013.07.042Xu Y and Nguyen D and Davidson J and Panagiotopoulos C
PubMed: 2313346511 / 2012
Ho J and Panagiotopoulos C and McCrindle B and Grisaru S and Pringsheim T
PubMed: 2408281510 / 2012
Ronsley R and Rayter M and Smith D and Davidson J and Panagiotopoulos C
PubMed: 2254606105 / 2012
Panagiotopoulos C and Ronsley R and Kuzeljevic B and Davidson J
PubMed: 2229696601 / 2012
Canadian Journal of Psychiatry
Ronsley, R. and Rayter, M. and Smith, D. and Davidson, J. and Panagiotopoulos, C.
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Xu, Y. and Nguyen, D. and Davidson, J. and Panagiotopoulos, C.
Pediatric Diabetes
Amed, S. and Hamilton, J.K. and Sellers, E.A. and Panagiotopoulos, C. and Hadjiyannakis, S. and Shah, B.R. and Booth, G.L. and Laubscher, T.A. and Dannenbaum, D. and Dean, H.
DOI: 10.1111/j.1399-5448.2012.00859.xTranslational Psychiatry
Devlin, A.M. and Ngai, Y.F. and Ronsley, R. and Panagiotopoulos, C.
DOI: 10.1038/tp.2011.68International journal of circumpolar health
Tomlin, D. and Naylor, P.J. and McKay, H. and Zorzi, A. and Mitchell, M. and Panagiotopoulos, C.
International Journal of Circumpolar Health
Tomlin, D. and Naylor, P.J. and Mckay, H. and Zorzi, A. and Mitchell, M. and Panagiotopoulos, C.
DOI: 10.3402/ijch.v71i0.17999British Columbia Medical Journal
Horn, M. and Procyshyn, R.M. and Warburton, W.P. and Tregillus, V. and Cavers, W. and Davidson, J. and Panagiotopoulos, C.
Canadian Journal of Psychiatry
Panagiotopoulos, C. and Ronsley, R. and Kuzeljevic, B. and Davidson, J.
Pediatric Critical Care Medicine
Karen Trudel and Shubhayan Sanatani and Constadina Panagiotopoulos
DOI: 10.1097/pcc.0b013e3181e2a38801 / 2011
Diabetes
Qin, H. and Lee, I.-F. and Panagiotopoulos, C. and Wang, X. and Chu, A.D. and Utz, P.J. and Priatel, J.J. and Tan, R.
DOI: 10.2337/db09-1706Journal of the Canadian Academy of Child and Adolescent Psychiatry
Ho, J. and Panagiotopoulos, C. and Mccrindle, B. and Grisaru, S. and Pringsheim, T.
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Pringsheim, T. and Panagiotopoulos, C. and Davidson, J. and Ho, J.
American Journal of Transplantation
Klimek, A.M. and Soukhatcheva, G. and Thompson, D.M. and Warnock, G.L. and Salehi, M. and Rilo, H. and DAlessio, D. and Meneilly, G.S. and Panagiotopoulos, C. and Verchere, C.B.
DOI: 10.1111/j.1600-6143.2010.03435.xJournal of the Canadian Academy of Child and Adolescent Psychiatry
Ronsley, R. and Raghuram, K. and Davidson, J. and Panagiotopoulos, C.
Paediatrics and Child Health
Pringsheim, T. and Doja, A. and Belanger, S. and Patten, S. and Casselman, L. and Davidson, J. and Grisaru, S. and Ho, J. and Jabbal, R. and MacKean, G. and McCrindle, B. and McLennan, J. and Palda, V. and Panagiotopoulos, C. and Pearce, M. and Ponesse, J. and Thomas, R. and Waheed, W. and Wilkes, C.
Paediatrics and Child Health
Pringsheim, T. and Panagiotopoulos, C. and Davidson, J. and Ho, J. and Belanger, S. and Casselman, L. and Doja, A. and Grisaru, S. and Jabbal, R. and MacKean, G. and McCrindle, B. and McLennan, J. and Palda, V. and Patten, S. and Pearce, M. and Ponesse, J. and Thomas, R. and Waheed, W. and Wilkes, C.
Journal of Pediatrics
Amed, S. and Dean, H. and Sellers, E.A.C. and Panagiotopoulos, C. and Shah, B.R. and Booth, G.L. and Laubscher, T.A. and Dannenbaum, D. and Hadjiyannakis, S. and Hamilton, J.K.
DOI: 10.1016/j.jpeds.2011.01.017Paediatrics and Child Health
Ho, J. and Panagiotopoulos, C. and McCrindle, B. and Grisaru, S. and Pringsheim, T. and Belanger, S. and Casselman, L. and Davidson, J. and Doja, A. and Jabbal, R. and MacKean, G. and McLennan, J. and Palda, V. and Patten, S. and Pearce, M. and Ponesse, J. and Thomas, R. and Waheed, W. and Wilkes, C.
International Journal of Environmental Research and Public Health
Panagiotopoulos, C. and Ronsley, R. and Al-Dubayee, M. and Brant, R. and Kuzeljevic, B. and Rurak, E. and Cristall, A. and Marks, G. and Sneddon, P. and Hinchliffe, M. and Chanoine, J.-P. and Msse, L.C.
DOI: 10.3390/ijerph8124662Journal of the Canadian Academy of Child and Adolescent Psychiatry
Panagiotopoulos, C. and Ronsley, R. and Elbe, D. and Davidson, J. and Smith, D.H.
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Chovil, N. and Panagiotopoulos, C.
Diabetes Care
Amed, S. and Dean, H.J. and Panagiotopoulos, C. and Sellers, E.A.C. and Hadjiyannakis, S. and Laubscher, T.A. and Dannenbaum, D. and Shah, B.R. and Booth, G.L. and Hamilton, J.K.
DOI: 10.2337/dc09-1013Journal of Immunology
Marwaha, A.K. and Crome, S.Q. and Panagiotopoulos, C. and Berg, K.B. and Qin, H. and Ouyang, Q. and Xu, L. and Priatel, J.J. and Levings, M.K. and Tan, R.
DOI: 10.4049/jimmunol.1001860Pediatric Cardiology
Alghamdi, M.H. and Steinraths, M. and Panagiotopoulos, C. and Potts, J.E. and Sandor, G.G.S.
DOI: 10.1007/s00246-010-9704-yRural and remote health
Naylor, P.J. and Scott, J. and Drummond, J. and Bridgewater, L. and McKay, H.A. and Panagiotopoulos, C.
Pediatric Exercise Science
Mitchell, M.S. and Gaul, C.A. and Naylor, P.-J. and Panagiotopoulos, C.
American Journal of Transplantation
Klimek, A.M. and Soukhatcheva, G. and Thompson, D.M. and Warnock, G.L. and Salehi, M. and Rilo, H. and D'Alessio, D. and Meneilly, G.S. and Panagiotopoulos, C. and Verchere, C.B.
DOI: 10.1111/j.1600-6143.2009.02740.xJournal of Child and Adolescent Psychopharmacology
Weiss, M. and Panagiotopoulos, C. and Giles, L. and Gibbins, C. and Kuzeljevic, B. and Davidson, J. and Harrison, R.
DOI: 10.1089/cap.2009.0050Canadian Journal of Psychiatry
Panagiotopoulos, C. and Ronsley, R. and Davidson, J.
Paediatrics and Child Health
Wahi, G. and Zorzi, A. and Macnab, A. and Panagiotopoulos, C.
Canadian journal of rural medicine : the official journal of the Society of Rural Physicians of Canada = Journal canadien de la mdecine rurale : le journal officiel de la Socit de mdecine rurale du Canada
Zorzi, A. and Wahi, G. and Macnab, A.J. and Panagiotopoulos, C.
Air Medical Journal
Gagnon, R. and Gagnon, F. and Panagiotopoulos, C.
DOI: 10.1016/j.amj.2008.04.001Canadian Journal of Diabetes
Nichol, H. and Retallack, J. and Panagiotopoulos, C.
Canadian Journal of Diabetes
Constadina Panagiotopoulos
DOI: 10.1016/s1499-2671(07)12005-001 / 2007
Rural and remote health
Panagiotopoulos, C. and Rozmus, J. and Gagnon, R.E. and Macnab, A.J.
American Journal of Medical Genetics, Part A
Bretherick, K.L. and Metzger, D.L. and Chanoine, J.-P. and Panagiotopoulos, C. and Watson, S.K. and Lam, W.L. and Fluker, M.R. and Brown, C.J. and Robinson, W.P.
DOI: 10.1002/ajmg.a.31679Diabetes
Ouyang, Q. and Standifer, N.E. and Qin, H. and Gottlieb, P. and Verchere, C.B. and Nepom, G.T. and Tan, R. and Panagiotopoulos, C.
DOI: 10.2337/db06-0065Diabetes
Standifer, N.E. and Ouyang, Q. and Panagiotopoulos, C. and Verchere, C.B. and Tan, R. and Greenbaum, C.J. and Pihoker, C. and Nepom, G.T.
DOI: 10.2337/db06-0066Current Opinion in Endocrinology and Diabetes
Standifer, N.E. and Panagiotopoulos, C. and Tan, R.
Canadian Journal of Diabetes
Trudeau, J.D. and Panagiotopoulos, C. and Verchere, C.B. and Tan, R.
Current Diabetes Reports
Constadina Panagiotopoulos and Jacqueline D. Trudeau and Rusung Tan
DOI: 10.1007/s11892-004-0062-004 / 2004
British Columbia Medical Journal
Panagiotopoulos, C.
Diabetes
Panagiotopoulos, C. and Qin, H. and Tan, R. and Verchere, C.B.
DOI: 10.2337/diabetes.52.11.2647Canadian Journal of Diabetes
Panagiotopoulos, C. and Preston, J.M. and Stewart, L.L. and Metzger, D.L. and Chanoine, J.-P.
Pediatrics
Panagiotopoulos, C. and McCrindle, B.W. and Hick, K. and Katzman, D.K.
Pediatric Research
Constadina Panagiotopoulos and Brian W. McCrindle and Katherine Hick and Debra K. Katzman
DOI: 10.1203/00006450-199704001-0005004 / 1997
Clinical and Investigative Medicine
Low, J.A. and Panagiotopoulos, C. and Smith, J.T. and Tang, W. and Derrick, E.J.
American Journal of Obstetrics and Gynecology
Low, J.A. and Panagiotopoulos, C. and Derrick, E.J.
DOI: 10.1016/0002-9378(95)90003-9American Journal of Obstetrics and Gynecology
James A. Low and Constadina Panagiotopoulos and E.Jane Derrick
DOI: 10.1016/s0002-9378(94)70101-604 / 1994
Type 1 diabetes mellitus arises from an autoimmune process directed against pancreatic beta cells in both humans and non-obese diabetic (NOD) mice. The destruction of beta cells is understood to be mediated by CD8+ cytotoxic T lymphocytes (CTL), though many other cell types are beginning to emerge as additional candidates in the disease progression. In collaboration with Dr. Rusung Tan, we are examining NK cells and subsets of proinflammatory T cells implicated in T1D. With Dr. Bruce Verchere, we are studying the mechanisms of beta cell failure in islet transplantation.
Through longstanding relationships with three Tsimshian communities in BC and at their request, we have conducted diabetes screening and determined a high prevalence of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) among youth residing in the region. This was the impetus behind the modification, implementation and evaluation of Action Schools! BC and Healthy Buddies programs for the communities’ specific settings. We are currently expanding this modified program to a community in Nunavut at their request.
In BC, mental illness occurs in 15% of children and adolescents, many of whom are treated with atypical antipsychotics (AAPs). To evaluate the metabolic sequelae of AAP use in youth, we have since 2006 conducted a retrospective chart review at BC Children’s Hospital (BCCH), developed a draft Metabolic Assessment and Monitoring Tool, and undertaken various knowledge translation initiatives at BCCH, Vancouver Coastal Health and beyond. These include the development of Healthy Living Toolkit, implementation of Metabolic Monitoring Tool in community mental health teams and the first Pediatric Provincial Mental Health Metabolic Program. We seek to have an immediate impact to improve the health of AAP-treated youth by enhancing the knowledge base of healthcare providers and families. This work is funded by multiple stakeholders, including the Lawson Foundation and the BC Provincial Health Services Authority.
Abbott Nutrition Young Investigator Award in Research, Western Society for Pediatric Research – 2013
Leading Practice Award, Accreditation Canada – 2013
Speaking of Food and Healthy Living Award, Dietitians of Canada – 2012
Every day, our researchers work towards breakthroughs to transform the lives of kids in BC and around the world. Learn about our latest innovations and advancements in child health.
With a Bachelor of Applied Science in Chemical and Biological Engineering (BASc) degree and a Doctor of Medicine (MD), Dr. Favel has recently completed a Master of Public Health (MPH) and the highly competitive Clinician Investigator program at the University of British Columbia (UBC). Her supervisors at BC Children’s are Childhood Diseases investigator Dr. Dina…
Congratulations to the BC Children's and BC Women's investigators who were awarded funding through the Canadian Institutes of Health Research (CIHR) Project Grant Fall 2020 competition. Our research community received around $6 million in new research grants.
Not only do parents of children with Type 1 diabetes need to watch their child’s blood sugar levels, they also need to pay attention to their kid’s blood pressure.
At BC Children’s, we are making discoveries that save lives and transform health care for children in our province and around the world. Our research portfolio includes basic, clinical, population, and public health research.
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BC Children's Hospital Research Institute operates on the ancestral and unceded territory of the Coast Salish peoples — xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh (Squamish), and Səl̓ílwətaʔ/Selilwitulh (Tsleil-Waututh) Nations. Further, this acknowledgement, gratitude, and respect extends to all of the First Nations communities on whose territories the Research Institute builds relationships and operates in British Columbia.
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