- Overview
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The central focus of my research is mental health and addictions, with a particular emphasis on psychosis and the medications used in its treatment. My research program is based on a multidisciplinary and translational approach that spans from "bench to bedside," as I maintain active research programs in both clinical and related preclinical research.
Working in collaboration with some of Canada's finest researchers, I study "psychosis" from multiple different perspectives. These include both idiopathic schizophrenia-spectrum disorders as well as psychostimulant drug-induced psychosis. Despite different etiologies and patient populations, these conditions share many similarities in terms of symptoms and treatment, and all can be studied in a translational manner. Additional interests include the mechanisms underlying the efficacy and side-effects of antipsychotic drugs, as well as the use of cannabinoids in medicine.
- Publications
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Differential sensitivity of intraindividual variability dispersion and global cognition in the prediction of functional outcomes and mortality in precariously housed and homeless adults
Clinical Neuropsychologist
Blumberg, M.J. and Petersson, A.M. and Jones, P.W. and Jones, A.A. and Panenka, W.J. and Leonova, O. and Vila-Rodriguez, F. and Lang, D.J. and Barr, A.M. and MacEwan, G.W. and Buchanan, T. and Honer, W.G. and Gicas, K.M.
DOI: 10.1080/13854046.2024.2325167
2024Multilayer depressive symptom networks in adults with bodily pain living in precarious housing or homelessness
European Archives of Psychiatry and Clinical Neuroscience
Jones, A.A. and Cho, L.L. and Gicas, K.M. and Procyshyn, R.M. and Vila-Rodriguez, F. and Stubbs, J.L. and Leonova, O. and Buchanan, T. and Thornton, A.E. and Lang, D.J. and MacEwan, G.W. and Panenka, W.J. and Barr, A.M. and Field, T.S. and Honer, W.G.
DOI: 10.1007/s00406-023-01664-0
2024Impact of patient-specific factors on clozapine metabolism in individuals with treatment-resistant schizophrenia or schizoaffective disorder
Journal of Psychopharmacology
Rafizadeh, R. and Sooch, A. and Risi, A. and Bihelek, N. and Kanegawa, K. and Barr, A.M. and White, R.F. and Schütz, C.G. and Bousman, C.A.
DOI: 10.1177/02698811241241394
2024A scoping review of the effects of mushroom and fungus extracts in rodent models of depression and tests of antidepressant activity
Frontiers in Pharmacology
Wang, C.K. and Kim, G. and Aleksandrova, L.R. and Panenka, W.J. and Barr, A.M.
DOI: 10.3389/fphar.2024.1387158
2024A Novel Leu-Enkephalin Prodrug Produces Pain-Relieving and Antidepressant Effects
Molecular Pharmaceutics
Hohenwarter, L. and Puil, E. and Rouhollahi, E. and Bohrmann, L. and Lu, S. and Saatchi, K. and Häfeli, U.O. and Barr, A. and Böttger, R. and Viswanadham, K.D. and Li, S.-D.
DOI: 10.1021/acs.molpharmaceut.3c00807
2024A systematic review and meta-analysis of synthetic cathinone use and psychosis
Psychopharmacology
Daswani, R.R. and Choles, C.M. and Kim, D.D. and Barr, A.M.
DOI: 10.1007/s00213-024-06569-x
2024Relationship between drug-induced movement disorders and psychosis in adults living in precarious housing or homelessness
Journal of Psychiatric Research
Kim, D.D. and Procyshyn, R.M. and Jones, A.A. and Gicas, K.M. and Jones, P.W. and Petersson, A.M. and Lee, L.H.N. and McLellan-Carich, R. and Cho, L.L. and Panenka, W.J. and Leonova, O. and Lang, D.J. and Thornton, A.E. and Honer, W.G. and Barr, A.M.
DOI: 10.1016/j.jpsychires.2024.01.003
2024Differences in those who prefer smoking cannabis to other consumption forms for mental health: what can be learned to promote safer methods of consumption?
Journal of Addictive Diseases
Lindsay A. Lo and Caroline A. MacCallum and Jade C. Yau and Alasdair M. Barr
DOI: 10.1080/10550887.2022.2107332
07/2023Clinical Handbook of Psychotropic Drugs
DOI: 10.1027/00632-000
06/2023Reduction in Substance-Related Composite Harm Scores Through Street Soccer
Cureus
Alan T Bates and Lurdes Tse-Agha and Arun Agha and John-Jose Nunez and Heidi N Boyda and Andrea A Jones and Alasdair M Barr and William G Honer and Fidel Vila-Rodriguez
DOI: 10.7759/cureus.39650
05/2023Using serial position effects to investigate memory dysfunction in homeless and precariously housed persons
Clinical Neuropsychologist
Gicas, K.M. and Benitah, K. and Thornton, A.E. and Petersson, A.M. and Jones, P.W. and Stubbs, J.L. and Jones, A.A. and Panenka, W.J. and Lang, D.J. and Leonova, O. and Vila-Rodriguez, F. and Barr, A.M. and Buchanan, T. and Su, W. and Vertinsky, A.T. and Rauscher, A. and MacEwan, G.W. and Honer, W.G.
DOI: 10.1080/13854046.2023.2178513
2023A scoping review of psychiatric conditions associated with chronic pain in the homeless and marginally housed population
Frontiers in Pain Research
Rintoul, K. and Song, E. and McLellan-Carich, R. and Schjelderup, E.N.R. and Barr, A.M.
DOI: 10.3389/fpain.2023.1020038
2023Rasch analysis of the beck depression inventory in a homeless and precariously housed sample
Psychiatry Research
Cho, L.L. and Jones, A.A. and Gao, C. and Leonova, O. and Vila-Rodriguez, F. and Buchanan, T. and Lang, D.J. and MacEwan, G.W. and Procyshyn, R.M. and Panenka, W.J. and Barr, A.M. and Thornton, A.E. and Gicas, K.M. and Honer, W.G. and Barbic, S.P.
DOI: 10.1016/j.psychres.2023.115331
2023Movement disorders associated with substance use in adults living in precarious housing or homelessness
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Kim, D.D. and Procyshyn, R.M. and Jones, A.A. and Lee, L.H.N. and Panenka, W.J. and Stubbs, J.L. and Cho, L.L. and Leonova, O. and Gicas, K.M. and Thornton, A.E. and Lang, D.J. and MacEwan, G.W. and Honer, W.G. and Barr, A.M.
DOI: 10.1016/j.pnpbp.2023.110795
2023Cannabidiol-associated hepatotoxicity: A systematic review and meta-analysis
Journal of Internal Medicine
Lo, L.A. and Christiansen, A. and Eadie, L. and Strickland, J.C. and Kim, D.D. and Boivin, M. and Barr, A.M. and MacCallum, C.A.
DOI: 10.1111/joim.13627
2023Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared with the general population
BMJ Neurology Open
Stubbs, J.L. and Jones, A.A. and Wolfman, D. and Chan, R.C.Y. and Vila-Rodriguez, F. and Vertinsky, A.T. and Heran, M.K. and Su, W. and Lang, D.J. and Field, T.S. and Gicas, K.M. and Woodward, M.L. and Thornton, A.E. and Barr, A.M. and Leonova, O. and Macewan, W. and Rauscher, A. and Honer, W.G. and Panenka, W.J.
DOI: 10.1136/bmjno-2022-000349
2023Are Younger Medical Cannabis Users at Risk? Comparing Patterns of Use and Mental Health in Younger and Older Medical Cannabis Dispensary Users
Children and Teenagers
DOI: 10.22158/ct.v6n2p1
2023Medical cannabis and use in migraine
Medicinal Usage of Cannabis and Cannabinoids
Jiang, J.X.R. and Barr, A.M.
DOI: 10.1016/B978-0-323-90036-2.00004-1
2023Exploring medical cannabis use in individuals with a traumatic brain injury
Exploration of Medicine
Schjelderup, E.N.R. and MacCallum, C.A. and Lo, L.A. and Dhillon, J. and Christiansen, A. and Pistawka, C. and Rintoul, K. and Panenka, W.J. and Barr, A.M.
DOI: 10.37349/emed.2023.00150
2023Developing prediction models for symptom severity around the time of discharge from a tertiary-care program for treatment-resistant psychosis
Frontiers in Psychiatry
Lee, L.H.N. and Procyshyn, R.M. and White, R.F. and Gicas, K.M. and Honer, W.G. and Barr, A.M.
DOI: 10.3389/fpsyt.2023.1181740
2023Cannabis use preferences in women with myofascial pelvic pain: A cross-sectional study
European Journal of Obstetrics and Gynecology and Reproductive Biology: X
Yang, E.C. and Koenig, N.A. and Gong, M. and Brotto, L.A. and Barr, A.M. and Lee, T. and Yong, P.J. and Geoffrion, R.
DOI: 10.1016/j.eurox.2023.100192
2023Long-acting injectable antipsychotics for early psychosis: A comprehensive systematic review
PLOS ONE
Lulu Lian and David D. Kim and Ric M. Procyshyn and Diana Cázares and William G. Honer and Alasdair M. Barr
DOI: 10.1371/journal.pone.0267808
04/2022Risk factors for hippocampal cavities in a marginally housed population
Hippocampus
Cheng, A.Y.T. and Stubbs, J.L. and Barr, A.M. and Gicas, K.M. and Su, W. and Thornton, A.E. and Lang, D.J. and Hamzah, Y. and Leonova, O. and MacEwan, W.G. and Rauscher, A. and Honer, W.G. and Panenka, W.J.
DOI: 10.1002/hipo.23450
2022Chronic Treatment With Psilocybin Decreases Changes in Body Weight in a Rodent Model of Obesity
Frontiers in Psychiatry
Huang, J. and Pham, M. and Panenka, W.J. and Honer, W.G. and Barr, A.M.
DOI: 10.3389/fpsyt.2022.891512
2022Traumatic brain injury in precariously housed persons: Incidence and risks
eClinicalMedicine
O{'}Connor, T.A. and Panenka, W.J. and Livingston, E.M. and Stubbs, J.L. and Askew, J. and Sahota, C.S. and Feldman, S.J. and Buchanan, T. and Xu, L. and Hu, X.J. and Lang, D.J. and Woodward, M.L. and Thornton, W.L. and Gicas, K.M. and Vertinsky, A.T. and Heran, M.K. and Su, W. and MacEwan, G.W. and Barr, A.M. and Honer, W.G. and Thornton, A.E.
DOI: 10.1016/j.eclinm.2022.101277
2022Factors Associated with Problematic Cannabis Use in a Sample of Medical Cannabis Dispensary Users
Psychiatry and Clinical Psychopharmacology
Lo, L.A. and Maccallum, C.A. and Yau, J.C. and Panenka, W.J. and Barr, A.M.
DOI: 10.5152/pcp.2022.22358
2022Pain, opioid use, depressive symptoms, and mortality in adults living in precarious housing or homelessness: a longitudinal prospective study
Pain
Jones, A.A. and Cho, L.L. and Kim, D.D. and Barbic, S.P. and Leonova, O. and Byford, A. and Buchanan, T. and Vila-Rodriguez, F. and Procyshyn, R.M. and Lang, D.J. and Vertinsky, A.T. and MacEwan, G.W. and Rauscher, A. and Panenka, W.J. and Thornton, A.E. and Barr, A.M. and Field, T.S. and Honer, W.G.
DOI: 10.1097/j.pain.0000000000002619
2022Antipsychotic Drug-Induced Increases in Peripheral Catecholamines are Associated With Glucose Intolerance
Frontiers in Pharmacology
Boyda, H.N. and Pham, M. and Huang, J. and Ho, A.A. and Procyshyn, R.M. and Yuen, J.W.Y. and Honer, W.G. and Barr, A.M.
DOI: 10.3389/fphar.2022.765905
2022Efficacy and tolerability of aripiprazole versus D2 antagonists in the early course of schizophrenia: a systematic review and meta-analysis
npj Schizophrenia
David D. Kim and Alasdair M. Barr and Lulu Lian and Jessica W. Y. Yuen and Diane Fredrikson and William G. Honer and Allen E. Thornton and Ric M. Procyshyn
DOI: 10.1038/s41537-021-00158-z
12/2021Population pharmacokinetics and dosing of long-acting injectable antipsychotics
Journal of Psychiatry & Neuroscience
David D. Kim and Alasdair M. Barr and Reza Rafizadeh and Ric M. Procyshyn
DOI: 10.1503/jpn.210079
09/2021Psychometric properties and correlates of the Beck Depression Inventory in a community-based and homeless or precariously housed sample
Journal of Affective Disorders Reports
Lianne L. Cho and Andrea A. Jones and Skye Barbic and Olga Leonova and Fidel Vila-Rodriguez and Tari Buchanan and Donna J. Lang and G. William MacEwan and Ric M. Procyshyn and William J. Panenka and Alasdair M. Barr and Allen E. Thornton and Kristina M. Gicas and William G. Honer
DOI: 10.1016/j.jadr.2021.100229
09/2021Characterization of Bodily Pain and Use of Both Prescription and Non-Prescription Opioids in Tenants of Precarious Housing
Substance Use & Misuse
Michelle Lei and Kathryn Rintoul and Jacob L. Stubbs and David D. Kim and Andrea A. Jones and Yasmin Hamzah and Ric M. Procyshyn and Kristina M. Gicas and Lianne L. Cho and William J. Panenka and Allen E. Thornton and Donna J. Lang and G. William MacEwan and William G. Honer and Alasdair M. Barr
DOI: 10.1080/10826084.2021.1958865
08/2021Component Processes of Decision Making in a Community Sample of Precariously Housed Persons: Associations With Learning and Memory, and Health-Risk Behaviors
Frontiers in Psychology
Heather A. Baitz and Paul W. Jones and David A. Campbell and Andrea A. Jones and Kristina M. Gicas and Chantelle J. Giesbrecht and Wendy Loken Thornton and Carmelina C. Barone and Nena Y. Wang and William J. Panenka and Donna J. Lang and Fidel Vila-Rodriguez and Olga Leonova and Alasdair M. Barr and Ric M. Procyshyn and Tari Buchanan and Alexander Rauscher and G. William MacEwan and William G. Honer and Allen E. Thornton
DOI: 10.3389/fpsyg.2021.571423
07/2021Exercise and Worsening of Extrapyramidal Symptoms during Treatment with Long-Acting Injectable Antipsychotics
Pharmacy
David D. Kim and Donna J. Lang and Darren E. R. Warburton and Alasdair M. Barr and Randall F. White and William G. Honer and Ric M. Procyshyn
DOI: 10.3390/pharmacy9030123
07/2021Efficacy of long-acting injectable versus oral antipsychotic drugs in early psychosis: A systematic review and meta-analysis
Early Intervention in Psychiatry
Lulu Lian and David D. Kim and Ric M. Procyshyn and Diane H. Fredrikson and Diana C{\'{a}}zares and William G. Honer and Alasdair M. Barr
DOI: 10.1111/eip.13202
07/2021A ganglionic blocker and adrenoceptor ligands modify clozapine-induced insulin resistance
Psychoneuroendocrinology
Jessica W.Y. Yuen and Claire Wu and Cathy K. Wang and David D. Kim and Ric M. Procyshyn and William G. Panenka and William G. Honer and Alasdair M. Barr
DOI: 10.1016/j.psyneuen.2021.105257
05/2021Practical Strategies Using Medical Cannabis to Reduce Harms Associated With Long Term Opioid Use in Chronic Pain
Frontiers in Pharmacology
Caroline A. MacCallum and Lauren Eadie and Alasdair M. Barr and Michael Boivin and Shaohua Lu
DOI: 10.3389/fphar.2021.633168
04/2021Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample.
Acta neuropathologica
DOI: 10.1007/s00401-021-02282-7
PubMed: 33646358
03/2021Characterizing Traumatic Brain Injury and Its Association with Losing Stable Housing in a Community-based Sample : Caractérisation d'une lésion cérébrale traumatique et de son association avec la perte d'un logement stable dans un échantillon communautaire.
Canadian journal of psychiatry. Revue canadienne de psychiatrie
DOI: 10.1177/07067437211000665
PubMed: 33719613
03/2021Duration of Neurocognitive Impairment With Medical Cannabis Use: A Scoping Review.
Frontiers in psychiatry
DOI: 10.3389/fpsyt.2021.638962
PubMed: 33790818
03/2021A new hypertonic saline assay for analgesic screening in mice: effects of animal strain, sex, and diurnal phase.
Canadian journal of anaesthesia = Journal canadien d'anesthesie
DOI: 10.1007/s12630-021-01923-5
PubMed: 33598887
02/2021High-Dose Fluvoxamine Augmentation to Clozapine in Treatment-Resistant Psychosis.
Journal of clinical psychopharmacology
DOI: 10.1097/jcp.0000000000001342
PubMed: 33587389
02/2021A Focused Review of the Metabolic Side-Effects of Clozapine.
Frontiers in endocrinology
DOI: 10.3389/fendo.2021.609240
PubMed: 33716966
02/2021Dynamic networks of psychotic symptoms in adults living in precarious housing or homelessness
Psychological Medicine
Andrea A. Jones and Kristina M. Gicas and Sara Mostafavi and Melissa L. Woodward and Olga Leonova and Fidel Vila-Rodriguez and Ric M. Procyshyn and Alex Cheng and Tari Buchanan and Donna J. Lang and G. William MacEwan and William J. Panenka and Alasdair M. Barr and Allen E. Thornton and William G. Honer
DOI: 10.1017/s0033291720004444
01/2021Relationship between clozapine dose and severity of obsessive-compulsive symptoms.
Medical hypotheses
DOI: 10.1016/j.mehy.2021.110506
PubMed: 33515917
01/2021A comparison of the metabolic side-effects of the second-generation antipsychotic drugs risperidone and paliperidone in animal models.
PloS one
DOI: 10.1371/journal.pone.0246211
PubMed: 33508013
01/2021Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared to the general population
medRxiv
Stubbs, J.L. and Jones, A.A. and Wolfman, D. and Chan, R.C.Y. and Vertinsky, A.T. and Heran, M.K. and Su, W. and Lang, D. and Field, T.S. and Gicas, K.M. and Woodward, M.L. and Thornton, A.E. and Barr, A.M. and Leonova, O. and MacEwan, G.W. and Rauscher, A. and Honer, W.G. and Panenka, W.J.
DOI: 10.1101/2021.11.03.21265661
2021Recreational Cannabis Use Before and After Legalization in Women With Pelvic Pain
Obstetrics & Gynecology
Roxana Geoffrion and Emily C. Yang and Nicole A. Koenig and Lori A. Brotto and Alasdair M. Barr and Terry Lee and Catherine Allaire and Mohamed A. Bedaiwy and Paul J. Yong
DOI: 10.1097/aog.0000000000004207
12/2020Differential Effects of Acute Treatment With Antipsychotic Drugs on Peripheral Catecholamines
Frontiers in Psychiatry
Heidi N. Boyda and Amanzo A. Ho and Lurdes Tse and Ric M. Procyshyn and Jessica W. Y. Yuen and David D. Kim and William G. Honer and Alasdair M. Barr
DOI: 10.3389/fpsyt.2020.617428
12/2020Cerebral Small Vessel Disease, Risk Factors, and Cognition in Tenants of Precarious Housing
Stroke
DOI: 10.1161/strokeaha.120.030446
10/2020Differential effects of cannabis exposure during early versus later adolescence on the expression of psychosis in homeless and precariously housed adults
Progress in Neuro-Psychopharmacology and Biological Psychiatry
DOI: 10.1016/j.pnpbp.2020.110084
09/2020Cannabis Extract CT-921 Has a High Efficacy–Adverse Effect Profile in a Neuropathic Pain Model
Drug Design, Development and Therapy
DOI: 10.2147/dddt.s247584
08/2020Treatment algorithm for the use of psychopharmacological agents in individuals prenatally exposed to alcohol and/or with diagnosis of fetal alcohol spectrum disorder (FASD)
Journal of Population Therapeutics & Clinical Pharmacology
DOI: 10.15586/jptcp.v27i3.681
07/2020Associations of substance use, psychosis, and mortality among people living in precarious housing or homelessness: A longitudinal, community-based study in Vancouver, Canada
PLOS Medicine
DOI: 10.1371/journal.pmed.1003172
07/2020Amygdala Nuclei Volumes Are Selectively Associated With Social Network Size in Homeless and Precariously Housed Persons
Frontiers in Behavioral Neuroscience
DOI: 10.3389/fnbeh.2020.00097
06/2020Cognitive decline and mortality in a community-based sample of homeless and precariously housed adults: 9-year prospective study.
BJPsych open
DOI: 10.1192/bjo.2020.3
PubMed: 32043436
02/2020Traumatic brain injury in homeless and marginally housed individuals: a systematic review and meta-analysis
The Lancet Public Health
Stubbs, J.L. and Thornton, A.E. and Sevick, J.M. and Silverberg, N.D. and Barr, A.M. and Honer, W.G. and Panenka, W.J.
DOI: 10.1016/S2468-2667(19)30188-4
2020Traumatic Brain Injury: An Underappreciated Determinant of Health in Individuals Who are Homeless or Precariously Housed
World Neurosurgery
Stubbs, J.L. and Thornton, A.E. and Silverberg, N.D. and Sevick, J.M. and Barr, A.M. and Honer, W.G. and Panenka, W.J.
DOI: 10.1016/j.wneu.2020.02.133
2020Clozapine-associated obsessive-compulsive symptoms and their management: A systematic review and analysis of 107 reported cases
Psychotherapy and Psychosomatics
Kim, D.D. and Barr, A.M. and Lu, C. and Stewart, S.E. and White, R.F. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1159/000505876
2020A comparison of the effects of clozapine and its metabolite norclozapine on metabolic dysregulation in rodent models
Neuropharmacology
Yuen, J.W.Y. and Wu, C. and Wang, C.K. and Kim, D.D. and Procyshyn, R.M. and Honer, W.G. and Barr, A.M.
DOI: 10.1016/j.neuropharm.2019.107717
2020Prefrontal fatty acid composition in schizophrenia and bipolar disorder: Association with reelin expression
Schizophrenia Research
Beasley, C.L. and Honer, W.G. and Ramos-Miguel, A. and Vila-Rodriguez, F. and Barr, A.M.
DOI: 10.1016/j.schres.2017.05.033
2020Decreased medial entorhinal cortical thickness in olanzapine exposed female rats is not ameliorated by exercise
Pharmacology Biochemistry and Behavior
Woodward, M.L. and Ker, A.H. and Barr, A.M. and Beasley, C.L. and Hercher, C. and Boyda, H.N. and Procyshyn, R.M. and Honer, W.G. and Lang, D.J.
DOI: 10.1016/j.pbb.2019.172834
2020Meet Our Editorial Board Member
Current Neuropharmacology
DOI: 10.2174/1570159x1709190729101055
08/2019Cognitive Impairment in Marginally Housed Youth: Prevalence and Risk Factors
Frontiers in Public Health
Waclawik, K. and Jones, A.A. and Barbic, S.P. and Gicas, K.M. and O'Connor, T.A. and Smith, G.N. and Leonova, O. and Mathias, S. and Barr, A.M. and Procyshyn, R.M. and Lang, D.J. and Woodward, M.L. and MacEwan, G.W. and Panenka, W.J. and Yamamoto, A. and Honer, W.G. and Thornton, A.E.
DOI: 10.3389/fpubh.2019.00270
2019Drugs of Abuse
Clinical Handbook of Psychotropic Drugs
2019Diffusion tensor imaging of neurocognitive profiles in a community cohort living in marginal housing
Brain and Behavior
Gicas, K.M. and Cheng, A. and Rawtaer, I. and Willi, T.S. and Panenka, W.J. and Lang, D.J. and Smith, G.N. and Vila-Rodriguez, F. and Leonova, O. and Giesbrecht, C.J. and Jones, A.A. and Barr, A.M. and Procyshyn, R.M. and Buchanan, T. and MacEwan, G.W. and Su, W. and Vertinsky, A.T. and Rauscher, A. and O?Rourke, N. and Loken Thornton, W. and Thornton, A.E. and Honer, W.G.
DOI: 10.1002/brb3.1233
2019Volumes of the Hippocampal Formation Differentiate Component Processes of Memory in a Community Sample of Homeless and Marginally Housed Persons
Archives of Clinical Neuropsychology
Gicas, K.M. and Thornton, A.E. and Waclawik, K. and Wang, N. and Jones, A.A. and Panenka, W.J. and Lang, D.J. and Smith, G.N. and Vila-Rodriguez, F. and Leonova, O. and Barr, A.M. and Procyshyn, R.M. and Buchanan, T. and Su, W. and Vertinsky, A.T. and Rauscher, A. and Macewan, G.W. and Honer, W.G.
DOI: 10.1093/arclin/acy066
2019The synaptic pathology of cognitive life
Dialogues in Clinical Neuroscience
Honer, W.G. and Ramos-Miguel, A. and Alamri, J. and Sawada, K. and Barr, A.M. and Schneider, J.A. and Bennett, D.A.
DOI: 10.31887/DCNS.2019.21.3/whoner
2019The SNAP25 Interactome in Ventromedial Caudate in Schizophrenia Includes the Mitochondrial Protein ARF1
Neuroscience
Ramos-Miguel, A. and Barakauskas, V. and Alamri, J. and Miyauchi, M. and Barr, A.M. and Beasley, C.L. and Rosoklija, G. and Mann, J.J. and Dwork, A.J. and Moradian, A. and Morin, G.B. and Honer, W.G.
DOI: 10.1016/j.neuroscience.2018.12.045
2019Repeated Testing with the Hypertonic Saline Assay in Mice for Screening of Analgesic Activity
Anesthesia and Analgesia
Asiri, Y.I. and Fung, T. and Schwarz, S.K.W. and Barr, A.M. and Puil, E. and Macleod, B.A.
DOI: 10.1213/ANE.0000000000003593
2019Characterization of mental health in cannabis dispensary users, using structured clinical interviews and standardized assessment instruments
BMC Psychiatry
Yau, J.C. and Yu, S.M. and Panenka, W.J. and Pearce, H. and Gicas, K.M. and Procyshyn, R.M. and MacCallum, C. and Honer, W.G. and Barr, A.M.
DOI: 10.1186/s12888-019-2324-z
2019Social and structural factors associated with substance use within the support network of adults living in precarious housing in a socially marginalized neighborhood of Vancouver, Canada
PLoS ONE
Knerich, V. and Jones, A.A. and Seyedin, S. and Siu, C. and Dinh, L. and Mostafavi, S. and Barr, A.M. and Panenka, W.J. and Thornton, A.E. and Honer, W.G. and Rutherford, A.R.
DOI: 10.1371/journal.pone.0222611
2019Reduced SNAP25 Protein Fragmentation Contributes to SNARE Complex Dysregulation in Schizophrenia Postmortem Brain
Neuroscience
Ramos-Miguel, A. and Gicas, K. and Alamri, J. and Beasley, C.L. and Dwork, A.J. and Mann, J.J. and Rosoklija, G. and Cai, F. and Song, W. and Barr, A.M. and Honer, W.G.
DOI: 10.1016/j.neuroscience.2018.12.015
2019Characterizing traumatic brain injury and its association with homelessness in a community-based sample of precariously housed adults and youth
medRxiv
Stubbs, J.L. and Thornton, A.E. and Gicas, K.M. and O?Connor, T.A. and Livingston, E.M. and Lu, H.Y. and Mehta, A.K. and Lang, D.J. and Vertinsky, A.T. and Field, T.S. and Heran, M.K. and Leonova, O. and Buchanan, T. and Barr, A.M. and MacEwan, G.W. and Honer, W.G. and Panenka, W.J.
DOI: 10.1101/19004606
2019Prevalence and risk factors of brain infarcts and associations with cognitive performance in tenants of marginal housing
Journal of the American Heart Association
Zhou, L.W. and Panenka, W.J. and Jones, A.A. and Gicas, K.M. and Thornton, A.E. and Heran, M.K.S. and Volders, D. and Lang, D.J. and Vertinsky, A.T. and Rauscher, A. and Su, W. and Barr, A.M. and Macewan, G.W. and Honer, W.G. and Field, T.S.
DOI: 10.1161/JAHA.118.011412
2019A comparison of regional brain volumes and white matter connectivity in subjects with stimulant induced psychosis versus schizophrenia
Psychopharmacology
Alexander, P.D. and Gicas, K.M. and Cheng, A. and Lang, D.J. and Procyshyn, R.M. and Vertinsky, A.T. and Panenka, W.J. and Thornton, A.E. and Rauscher, A. and Wong, J.Y.X. and Chan, T. and Jones, A.A. and Vila-Rodriguez, F. and Honer, W.G. and Barr, A.M.
DOI: 10.1007/s00213-019-05298-w
2019Clozapine-induced obsessive– compulsive symptoms: Mechanisms and treatment
Journal of Psychiatry and Neuroscience
Kim, D.D. and Barr, A.M. and White, R.F. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1503/jpn.180087
2019Traumhaft und grenzenlos
Simone Weiss, Ekkehart Paditz, Simone Weiss, Werner Sauseng, Ekkehart Paditz, Gerhard Klo¨sch, Brigitte Holzinger, Leonie M. Paciello, Christian F. Poets, Mirja Quante, Anne Schomo¨ller, Frank Mayer, Thomas Erler, Alasdair M. Barr, Georg Dorffner, Dean Elbe, Alison Frieling, Osman S. Ipsiroglu, Sue MacCabe, Moira Plant, Beth Potter, Dorothy Reid, Stefan Seidel, Barbara Schneider, Karen Spruyt, Sylvia Stockler, Dorothee Veer, Frank Kirchhoff, Ruth Luigart, Ursula Kiechl-Kohlendorfer, Astrid Sonnleitner, Larissa Krenn, Adelheid Gautsch-Kofler, Marie Hausegger, Renata Grgic-Mustafic, Ernst Eber, Reinhold Kerbl, Sarah Rey, Maren Cordi, Jens Acker, Bernhard Schlu¨ter, Patrizia Kutz, Uta Schu¨rmann, Claudia Roll, Sylvia Mu¨ller-Hagedorn, Franka Stahl, Mathias Schmu¨cker, Nilu¨fer U¨nal, Alexander Du¨ck, Christoph Berger, Andreas van Egmond-Fro¨hlich, Alessandro Onofri, Ulrike Sengeis, Claudia Bock, Anastasios Bouikidis, Susanne Harner, Uli Steiner, Sebastian Kerzel, Sabine Scholle, Alfred Wiater
2019Cognitive profiles and associated structural brain networks in a multimorbid sample of marginalized adults
PLoS ONE
Gicas, K.M. and Jones, A.A. and Panenka, W.J. and Giesbrecht, C. and Lang, D.J. and Vila-Rodriguez, F. and Leonova, O. and Barr, A.M. and Procyshyn, R.M. and Su, W. and Rauscher, A. and Vertinsky, A.T. and Buchanan, T. and Macewan, G.W. and Thornton, A.E. and Honer, W.G.
DOI: 10.1371/journal.pone.0218201
2019Association between serum lipids and antipsychotic response in schizophrenia
Current Neuropharmacology
Kim, D.D. and Barr, A.M. and Fredrikson, D.H. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.2174/1570159X17666190228113348
2019Cannabis and Psychosis A Review of the Links
BC Schizophrenia Society
01/2018Clozapine, elevated heart rate and QTc prolongation
Journal of Psychiatry & Neuroscience
David D. Kim and Randall F. White and Alasdair M. Barr and William G. Honer and Ric M. Procyshyn
DOI: 10.1503/jpn.170135
01/2018Rapid change in fentanyl prevalence in a community-based, high-risk sample
JAMA Psychiatry
Jones, A.A. and Jang, K. and Panenka, W.J. and Barr, A.M. and MacEwan, G.W. and Thornton, A.E. and Honer, W.G.
DOI: 10.1001/jamapsychiatry.2017.4432
2018Exercise-induced hippocampal neurogenesis: 5-HT3 receptor antagonism by antipsychotics as a potential limiting factor in Schizophrenia
Molecular Psychiatry
Kim, D.D. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1038/s41380-018-0022-8
2018A systematic review of the effects of CYP2D6 phenotypes on risperidone treatment in children and adolescents
Child and Adolescent Psychiatry and Mental Health
Dodsworth, T. and Kim, D.D. and Procyshyn, R.M. and Ross, C.J. and Honer, W.G. and Barr, A.M.
DOI: 10.1186/s13034-018-0243-2
2018Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age
Neurobiology of Disease
Ramos-Miguel, A. and Jones, A.A. and Sawada, K. and Barr, A.M. and Bayer, T.A. and Falkai, P. and Leurgans, S.E. and Schneider, J.A. and Bennett, D.A. and Honer, W.G.
DOI: 10.1016/j.nbd.2018.02.006
2018Antipsychotic prescribing patterns on admission to and at discharge from a tertiary care program for treatment-resistant psychosis
PLoS ONE
Lee, L.H.N. and Procyshyn, R.M. and White, R.F. and Woodward, T.S. and Honer, W.G. and Barr, A.M.
DOI: 10.1371/journal.pone.0199758
2018Voluntary running influences the efficacy of fluoxetine in a model of postpartum depression
Neuropharmacology
Gobinath, A.R. and Richardson, R.J. and Chow, C. and Workman, J.L. and Lieblich, S.E. and Barr, A.M. and Galea, L.A.M.
DOI: 10.1016/j.neuropharm.2017.09.017
2018Cognitive deficits in individuals with methamphetamine use disorder: A meta-analysis
Addictive Behaviors
Potvin, S. and Pelletier, J. and Grot, S. and Hébert, C. and Barr, A. and Lecomte, T.
DOI: 10.1016/j.addbeh.2018.01.021
2018Clinical and functional characteristics of young adults living in single room occupancy housing: preliminary findings from a 10-year longitudinal study
Canadian Journal of Public Health
Barbic, S.P. and Jones, A.A. and Woodward, M. and Piercy, M. and Mathias, S. and Vila-Rodriguez, F. and Leonova, O. and Smith, G.N. and Buchanan, T. and Vertinsky, A.T. and Gillingham, S. and Panenka, W.J. and Rauscher, A. and Barr, A.M. and Procyshyn, R.M. and MacEwan, G.W. and Lang, D.J. and Thornton, A.E. and Heran, M.K. and Leon, A.M. and Krausz, M. and Honer, W.G.
DOI: 10.17269/s41997-018-0087-9
2018The utility of psychotropic drugs on patients with Fetal Alcohol Spectrum Disorder (FASD): a systematic review
Psychiatry and Clinical Psychopharmacology
Mela, M. and Okpalauwaekwe, U. and Anderson, T. and Eng, J. and Nomani, S. and Ahmed, A. and Barr, A.M.
DOI: 10.1080/24750573.2018.1458429
2018Clozapine-induced cardiovascular side effects and autonomic dysfunction: A systematic review
Frontiers in Neuroscience
Yuen, J.W.Y. and Kim, D.D. and Procyshyn, R.M. and White, R.F. and Honer, W.G. and Barr, A.M.
DOI: 10.3389/fnins.2018.00203
2018An intraplantar hypertonic saline assay in mice for rapid screening of analgesics
Anesthesia and Analgesia
Asiri, Y.I. and Fung, T. and Schwarz, S.K.W. and Asseri, K.A. and Welch, I.D. and Schuppli, C.A. and Barr, A.M. and Wall, R.A. and Puil, E. and MacLeod, B.A.
DOI: 10.1213/ANE.0000000000002525
2018Reversal of Dopamine Supersensitivity as a Mechanism of Action of Clozapine
Psychotherapy and Psychosomatics
Kim, D.D. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1159/000491700
2018Maternal exercise increases but concurrent maternal fluoxetine prevents the increase in hippocampal neurogenesis of adult offspring
Psychoneuroendocrinology
Gobinath, A.R. and Wong, S. and Chow, C. and Lieblich, S.E. and Barr, A.M. and Galea, L.A.M.
DOI: 10.1016/j.psyneuen.2018.02.027
2018Antipsychotic-Associated Symptoms of Tourette Syndrome: A Systematic Review
CNS Drugs
Kim, D.D. and Barr, A.M. and Chung, Y. and Yuen, J.W.Y. and Etminan, M. and Carleton, B.C. and White, R.F. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1007/s40263-018-0559-8
2018Statin add-on therapy for schizophrenia: Is the effect the same for clozapine?
Psychiatry Research
Kim, D.D. and Barr, A.M. and Thornton, A.E. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1016/j.psychres.2018.02.039
2018Effects of physical activity on the symptoms of Tourette syndrome: A systematic review
European Psychiatry
Kim, D.D. and Warburton, D.E.R. and Wu, N. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1016/j.eurpsy.2017.11.002
2018Exercise-associated extrapyramidal symptoms during treatment with long-acting injectable antipsychotic medications: A case report
Clinical Schizophrenia & Related Psychoses
David D. Kim and Donna J. Lang and Darren E. R. Warburton and Alasdair M. Barr and Randall F. White and William G. Honer and Ric M. Procyshyn
DOI: 10.3371/csrp.dkdl.071317
08/2017Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer’s disease
Acta Neuropathologica
Ramos-Miguel, A. and Sawada, K. and Jones, A.A. and Thornton, A.E. and Barr, A.M. and Leurgans, S.E. and Schneider, J.A. and Bennett, D.A. and Honer, W.G.
DOI: 10.1007/s00401-016-1647-9
2017Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample
Molecular Neurodegeneration
Ramos-Miguel, A. and García-Sevilla, J.A. and Barr, A.M. and Bayer, T.A. and Falkai, P. and Leurgans, S.E. and Schneider, J.A. and Bennett, D.A. and Honer, W.G. and García-Fuster, M.J.
DOI: 10.1186/s13024-017-0168-x
2017Heart-rate response to alpha 2 -adrenergic receptor antagonism by antipsychotics
Clinical Autonomic Research
Kim, D.D. and Lang, D.J. and Warburton, D.E.R. and Woodward, M.L. and White, R.F. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1007/s10286-017-0444-4
2017Characterization of white matter integrity deficits in cocaine-dependent individuals with substance-induced psychosis compared with non-psychotic cocaine users
Addiction Biology
Willi, T.S. and Barr, A.M. and Gicas, K. and Lang, D.J. and Vila-Rodriguez, F. and Su, W. and Thornton, A.E. and Leonova, O. and Giesbrecht, C.J. and Procyshyn, R.M. and Rauscher, A. and MacEwan, W.G. and Honer, W.G. and Panenka, W.J.
DOI: 10.1111/adb.12363
2017Verbal memory improvement in first-episode psychosis APOE-e4 carriers: A pleiotropic effect?
Neuropsychiatric Disease and Treatment
Vila-Rodriguez, F. and Lang, D.J. and Baitz, H. and Gicas, K. and Thorton, A.E. and Ehmann, T.S. and Smith, G.N. and Barr, A.M. and Torres, I.J. and Kopala, L.C. and William Macewan, G. and Müller, D.J. and Kennedy, J.L. and Honer, W.G.
DOI: 10.2147/NDT.S150488
2017Effects of exercise on serum triglycerides and symptoms of schizophrenia
Journal of Clinical Psychopharmacology
Kim, D.D. and Lang, D.J. and Warburton, D.E.R. and Barr, A.M. and Smith, G.N. and Thornton, A.E. and White, R.F. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1097/JCP.0000000000000648
2017Antipsychotic induced dopamine supersensitivity psychosis: A comprehensive review
Current Neuropharmacology
Yin, J. and Barr, A.M. and Ramos-Miguel, A. and Procyshyn, R.M.
DOI: 10.2174/1570159X14666160606093602
2017The Hotel Study - Clinical and Health Service Effectiveness in a Cohort of Homeless or Marginally Housed Persons
Canadian Journal of Psychiatry
Honer, W.G. and Cervantes-Larios, A. and Jones, A.A. and Vila-Rodriguez, F. and Montaner, J.S. and Tran, H. and Nham, J. and Panenka, W.J. and Lang, D.J. and Thornton, A.E. and Vertinsky, T. and Barr, A.M. and Procyshyn, R.M. and Smith, G.N. and Buchanan, T. and Krajden, M. and Krausz, M. and Macewan, G.W. and Gicas, K.M. and Leonova, O. and Langheimer, V. and Rauscher, A. and Schultz, K.
DOI: 10.1177/0706743717693781
2017Street soccer is played on a two-way street: Changes in attitudes and perceptions of Vancouver Street Soccer League volunteers
Unpublished
DOI: 10.13140/RG.2.2.31911.75685
2017Modifying medical trainees’ perspectives on vulnerable populations through engagement in community-based team sports: fostering the Health Advocate role
Unpublished
DOI: 10.13140/RG.2.2.15134.54085
2017A comparison of psychotic symptoms in subjects with methamphetamine versus cocaine dependence
Psychopharmacology
Alexander, P.D. and Gicas, K.M. and Willi, T.S. and Kim, C.N. and Boyeva, V. and Procyshyn, R.M. and Smith, G.N. and Thornton, A.E. and Panenka, W.J. and Jones, A.A. and Vila-Rodriguez, F. and Lang, D.J. and William MacEwan, G. and Honer, W.G. and Barr, A.M.
DOI: 10.1007/s00213-017-4551-7
2017Traumatic Brain Injury in a Community-Based Cohort of Homeless and Vulnerably Housed Individuals
Journal of Neurotrauma
Schmitt, T. and Thornton, A.E. and Rawtaer, I. and Barr, A.M. and Gicas, K.M. and Lang, D.J. and Vertinsky, A.T. and Rauscher, A. and Procyshyn, R.M. and Buchanan, T. and Cheng, A. and Mackay, S. and Leonova, O. and Langheimer, V. and Field, T.S. and Heran, M.K. and Vila-Rodriguez, F. and O'Connor, T.A. and Macewan, G.W. and Honer, W.G. and Panenka, W.J.
DOI: 10.1089/neu.2017.5076
2017Structural brain markers are differentially associated with neurocognitive profiles in socially marginalized people with multimorbid illness
Neuropsychology
Gicas, K.M. and Giesbrecht, C.J. and Panenka, W.J. and Lang, D.J. and Smith, G.N. and Vila-Rodriguez, F. and Leonova, O. and Jones, A.A. and Barr, A.M. and Procyshyn, R.M. and Buchanan, T. and MacEwan, G.W. and Su, W. and Vertinsky, A.T. and Rauscher, A. and Honer, W.G. and Thornton, A.E.
DOI: 10.1037/neu0000304
2017A Tetra-Primer Amplification Refractory System Technique for the Cost-Effective and Novel Genotyping of Eight Single-Nucleotide Polymorphisms of the Catechol-O-Methyltransferase Gene
Genetic Testing and Molecular Biomarkers
Wang, C.K. and Aleksic, A. and Xu, M.S. and Procyshyn, R.M. and Ross, C.J. and Vila-Rodriguez, F. and Ramos-Miguel, A. and Yan, R. and Honer, W.G. and Barr, A.M.
DOI: 10.1089/gtmb.2015.0304
2016Subcortical grey matter alterations in cocaine dependent individuals with substance-induced psychosis compared to non-psychotic cocaine users
Schizophrenia Research
Willi, T.S. and Lang, D.J. and Honer, W.G. and Smith, G.N. and Thornton, A.E. and Panenka, W.J. and Procyshyn, R.M. and Vila-Rodriguez, F. and Su, W. and Vertinsky, A.T. and Leonova, O. and Rauscher, A. and MacEwan, G.W. and Barr, A.M.
DOI: 10.1016/j.schres.2016.08.001
2016Factors affecting severity of positive and negative symptoms of psychosis in a polysubstance using population with psychostimulant dependence
Psychiatry Research
Willi, T.S. and Honer, W.G. and Thornton, A.E. and Gicas, K. and Procyshyn, R.M. and Vila-Rodriguez, F. and Panenka, W.J. and Aleksic, A. and Leonova, O. and Jones, A.A. and MacEwan, G.W. and Barr, A.M.
DOI: 10.1016/j.psychres.2016.04.059
2016Depression
Compendium of Therapeutics for Minor Ailments
2016Proposing the Use of Partial AUC as an Adjunctive Measure in Establishing Bioequivalence Between Deltoid and Gluteal Administration of Long-Acting Injectable Antipsychotics
European Journal of Drug Metabolism and Pharmacokinetics
Lee, L.H.N. and Choi, C. and Gershkovich, P. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1007/s13318-016-0348-z
2016Elevated clozapine plasma concentration secondary to a urinary tract infection: Proposed mechanisms
Journal of Psychiatry and Neuroscience
Lee, L.H.N. and White, R.F. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1503/jpn.150156
2016Quantitative mass spectrometry reveals changes in SNAP-25 isoforms in schizophrenia
Schizophrenia Research
Barakauskas, V.E. and Moradian, A. and Barr, A.M. and Beasley, C.L. and Rosoklija, G. and Mann, J.J. and Ilievski, B. and Stankov, A. and Dwork, A.J. and Falkai, P. and Morin, G.B. and Honer, W.G.
DOI: 10.1016/j.schres.2016.03.002
2016Response to the Letter to the Editor on "paliperidone Palmitate Long-Acting Injectable Given Intramuscularly in the Deltoid Versus the Gluteal Muscle: Are They Therapeutically Equivalent?"
Journal of Clinical Psychopharmacology
Yin, J. and Lee, L.H.N. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1097/JCP.0000000000000612
2016Insomnia
Compendium of Therapeutics for Minor Ailments
2016Breakthrough symptoms after switching long-acting injectable paliperidone palmitate from the gluteal to the deltoid site of administration
Journal of Psychiatry and Neuroscience
Procyshyn, R.M. and Banasch, J.L. and Barr, A.M. and Honer, W.G.
DOI: 10.1503/jpn.150206
2016Spines, Synapses, and Schizophrenia
Biological Psychiatry
Ramos-Miguel, A. and Barr, A.M. and Honer, W.G.
DOI: 10.1016/j.biopsych.2015.08.035
2015Treatment of clozapine-associated weight gain: A systematic review
European Journal of Clinical Pharmacology
Whitney, Z. and Procyshyn, R.M. and Fredrikson, D.H. and Barr, A.M.
DOI: 10.1007/s00228-015-1807-1
2015Paliperidone Palmitate Long-Acting Injectable Given Intramuscularly in the Deltoid Versus the Gluteal Muscle: Are They Therapeutically Equivalent?
Journal of Clinical Psychopharmacology
Yin, J. and Collier, A.C. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1097/JCP.0000000000000361
2015Exercise prevents downregulation of hippocampal presynaptic proteins following olanzapine-elicited metabolic dysregulation in rats: Distinct roles of inhibitory and excitatory terminals
Neuroscience
Ramos-Miguel, A. and Honer, W.G. and Boyda, H.N. and Sawada, K. and Beasley, C.L. and Procyshyn, R.M. and Barr, A.M.
DOI: 10.1016/j.neuroscience.2015.06.022
2015The Pharmacokinetics of Second-Generation Long-Acting Injectable Antipsychotics: Limitations of Monograph Values
CNS Drugs
Lee, L.H.N. and Choi, C. and Collier, A.C. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1007/s40263-015-0295-2
2015Neuroleptic malignant syndrome: A review from a clinically oriented perspective
Current Neuropharmacology
Tse, L. and Barr, A.M. and Scarapicchia, V. and Vila-Rodriguez, F.
DOI: 10.2174/1570159X13999150424113345
2015Increased SNARE Protein-Protein Interactions in Orbitofrontal and Anterior Cingulate Cortices in Schizophrenia
Biological Psychiatry
Ramos-Miguel, A. and Beasley, C.L. and Dwork, A.J. and Mann, J.J. and Rosoklija, G. and Barr, A.M. and Honer, W.G.
DOI: 10.1016/j.biopsych.2014.12.012
2015Cognition and plasma ratio of clozapine to N-desmethylclozapine in patients with clozapine-resistant schizophrenia
American Journal of Psychiatry
Thornton, A.E. and Procyshyn, R.M. and Barr, A.M. and MacEwan, G.W. and Honer, W.G.
DOI: 10.1176/appi.ajp.2015.15070899
2015Postoperative delirium following transcatheter aortic valve implantation: a historical cohort study,Délirium postopératoire après implantation de valve aortique transcathéter: une étude de cohorte historique
Canadian Journal of Anesthesia
Tse, L. and Bowering, J.B. and Schwarz, S.K.W. and Moore, R.L. and Burns, K.D. and Barr, A.M.
DOI: 10.1007/s12630-014-0254-2
2015White matter deficits assessed by diffusion tensor imaging and cognitive dysfunction in psychostimulant users with comorbid human immunodeficiency virus infection Psychiatry
BMC Research Notes
Tang, V.M. and Lang, D.J. and Giesbrecht, C.J. and Panenka, W.J. and Willi, T. and Procyshyn, R.M. and Vila-Rodriguez, F. and Jenkins, W. and Lecomte, T. and Boyda, H.N. and Aleksic, A. and Macewan, G.W. and Honer, W.G. and Barr, A.M.
DOI: 10.1186/s13104-015-1501-5
2015Mortality from treatable illnesses in marginally housed adults: A prospective cohort study
BMJ Open
Jones, A.A. and Vila-Rodriguez, F. and Leonova, O. and Langheimer, V. and Lang, D.J. and Barr, A.M. and Procyshyn, R.M. and Smith, G.N. and Schultz, K. and Buchanan, T. and Krausz, M. and Montaner, J.S. and Macewan, G.W. and Rauscher, A. and Panenka, W.J. and Thornton, A.E. and Honer, W.G.
DOI: 10.1136/bmjopen-2015-008876
2015Incidence of and Risk Factors for Delirium after Cardiac Surgery at a Quaternary Care Center: A Retrospective Cohort Study
Journal of Cardiothoracic and Vascular Anesthesia
Tse, L. and Schwarz, S.K.W. and Bowering, J.B. and Moore, R.L. and Barr, A.M.
DOI: 10.1053/j.jvca.2015.06.018
2015Effects of haloperidol and clozapine administration on oxidative stress in rat brain, liver and serum
Neuroscience Letters
Andreazza, A.C. and Barakauskas, V.E. and Fazeli, S. and Feresten, A. and Shao, L. and Wei, V. and Wu, C.H. and Barr, A.M. and Beasley, C.L.
DOI: 10.1016/j.neulet.2015.02.028
2015Development of a cost-efficient novel method for rapid, concurrent genotyping of five common single nucleotide polymorphisms of the brain derived neurotrophic factor (BDNF) gene by tetra-primer amplification refractory mutation system
International Journal of Methods in Psychiatric Research
Wang, C.K. and Xu, M.S. and Ross, C.J. and Lo, R. and Procyshyn, R.M. and Vila-Rodriguez, F. and White, R.F. and Honer, W.G. and Barr, A.M.
DOI: 10.1002/mpr.1475
2015A case of pseudo-Stauffer's syndrome related to asenapine use
Schizophrenia Research
Schultz, K. and Wang, L. and Barr, A. and Rodriguez, F.V.
DOI: 10.1016/j.schres.2015.10.015
2015Therapeutic Drug Levels of Second Generation Antipsychotics in Youth: A Systematic Review
Journal of Child and Adolescent Psychopharmacology
Whitney, Z. and Boyda, H.N. and Procyshyn, R.M. and Elbe, D. and Black, T. and Eslami, A. and Barr, A.M.
DOI: 10.1089/cap.2014.0044
2015Response trajectories to clozapine in a secondary analysis of pivotal trials support using treatment response to subtype schizophrenia
Canadian journal of psychiatry. Revue canadienne de psychiatrie
Honer, W.G. and Jones, A.A. and Thornton, A.E. and Barr, A.M. and Procyshyn, R.M. and Vila-Rodriguez, F.
2015Loss of Munc18-1 long splice variant in GABAergic terminals is associated with cognitive decline and increased risk of dementia in a community sample
Molecular Neurodegeneration
Ramos-Miguel, A. and Hercher, C. and Beasley, C.L. and Barr, A.M. and Bayer, T.A. and Falkai, P. and Leurgans, S.E. and Schneider, J.A. and Bennett, D.A. and Honer, W.G.
DOI: 10.1186/s13024-015-0061-4
2015Incidence and risk factors for impaired mobility in older cardiac surgery patients during the early postoperative period
Geriatrics and Gerontology International
Tse, L. and Bowering, J.B. and Schwarz, S.K.W. and Moore, R.L. and Sztramko, R. and Barr, A.M.
DOI: 10.1111/ggi.12269
2015Cardiovascular effects of acute treatment with the antipsychotic drug olanzapine in rats
Vascular Pharmacology
Leung, J.Y.T. and Pang, C.C.Y. and Procyshyn, R.M. and Barr, A.M.
DOI: 10.1016/j.vph.2014.06.003
2014Antidiabetic-drug combination treatment for glucose intolerance in adult female rats treated acutely with olanzapine
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Boyda, H.N. and Procyshyn, R.M. and Asiri, Y. and Wu, C. and Wang, C.K. and Lo, R. and Pang, C.C.Y. and Honer, W.G. and Barr, A.M.
DOI: 10.1016/j.pnpbp.2013.10.006
2014Pharmacological treatment of antipsychotic-induced dyslipidemia and hypertension
International Clinical Psychopharmacology
Tse, L. and Procyshyn, R.M. and Fredrikson, D.H. and Boyda, H.N. and Honer, W.G. and Barr, A.M.
DOI: 10.1097/YIC.0000000000000014
2014An evaluation of the effects of the novel antipsychotic drug lurasidone on glucose tolerance and insulin resistance: A comparison with olanzapine
PLoS ONE
Wu, C. and Yuen, J. and Boyda, H.N. and Procyshyn, R.M. and Wang, C.K. and Asiri, Y.I. and Pang, C.C.Y. and Honer, W.G. and Barr, A.M.
DOI: 10.1371/journal.pone.0107116
2014Routine exercise ameliorates the metabolic side-effects of treatment with the atypical antipsychotic drug olanzapine in rats
International Journal of Neuropsychopharmacology
Boyda, H.N. and Ramos-Miguel, A. and Procyshyn, R.M. and Töpfer, E. and Lant, N. and Choy, H.H.T. and Wong, R. and Li, L. and Pang, C.C.Y. and Honer, W.G. and Barr, A.M.
DOI: 10.1017/S1461145713000795
2014Prevalence and patterns of antipsychotic use in youth at the time of admission and discharge from an inpatient psychiatric facility
Journal of Clinical Psychopharmacology
Procyshyn, R.M. and Su, J. and Elbe, D. and Liu, A.Y. and Panenka, W.J. and Davidson, J. and Honer, W.G. and Barr, A.M.
DOI: 10.1097/JCP.0b013e3182a607dd
2014Improving metabolic and cardiovascular health at an early psychosis intervention program in Vancouver, Canada
Frontiers in Psychiatry
Fredrikson, D.H. and Boyda, H.N. and Tse, L. and Whitney, Z. and Pattison, M.A. and Ott, F.J. and Hansen, L. and Barr, A.M.
DOI: 10.3389/fpsyt.2014.00105
2014Clozapine administered once versus twice daily: Does it make a difference?
Medical Hypotheses
Procyshyn, R.M. and Vila-Rodriguez, F. and Honer, W.G. and Barr, A.M.
DOI: 10.1016/j.mehy.2013.11.043
2014Symptom changes in five dimensions of the Positive and Negative Syndrome Scale in refractory psychosis
European Archives of Psychiatry and Clinical Neuroscience
Woodward, T.S. and Jung, K. and Smith, G.N. and Hwang, H. and Barr, A.M. and Procyshyn, R.M. and Flynn, S.W. and van der Gaag, M. and Honer, W.G.
DOI: 10.1007/s00406-013-0460-x
2014Neurocognitive profiles of marginally housed persons with comorbid substance dependence, viral infection, and psychiatric illness
Journal of Clinical and Experimental Neuropsychology
Gicas, K.M. and Vila-Rodriguez, F. and Paquet, K. and Barr, A.M. and Procyshyn, R.M. and Lang, D.J. and Smith, G.N. and Baitz, H.A. and Giesbrecht, C.J. and Montaner, J.S. and Krajden, M. and Krausz, M. and MacEwan, G.W. and Panenka, W.J. and Honer, W.G. and Thornton, A.E.
DOI: 10.1080/13803395.2014.963519
2014Managing ADHD and disruptive behaviour disorders with combination psychostimulant and antipsychotic treatment
Journal of Psychiatry and Neuroscience
Elbe, D. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1503/jpn.130288
2014Peripheral adrenoceptors: The impetus behind glucose dysregulation and insulin resistance
Journal of Neuroendocrinology
Boyda, H.N. and Procyshyn, R.M. and Pang, C.C.Y. and Barr, A.M.
DOI: 10.1111/jne.12002
2013The hotel study: Multimorbidity in a community sample living in marginal housing
American Journal of Psychiatry
Vila-Rodriguez, F. and Panenka, W.J. and Lang, D.J. and Thornton, A.E. and Vertinsky, T. and Wong, H. and Barr, A.M. and Procyshyn, R.M. and Sidhu, J.J. and Smith, G.N. and Buchanan, T. and Krajden, M. and Krausz, M. and Montaner, J.S. and MacEwan, G.W. and Honer, W.G.
DOI: 10.1176/appi.ajp.2013.12111439
2013Personalized risk assessment of drug-related harm is associated with health outcomes
PLoS ONE
Jones, A.A. and Vila-Rodriguez, F. and Panenka, W.J. and Leonova, O. and Strehlau, V. and Lang, D.J. and Thornton, A.E. and Wong, H. and Barr, A.M. and Procyshyn, R.M. and Smith, G.N. and Buchanan, T. and Krajden, M. and Krausz, M. and Montaner, J.S. and MacEwan, G.W. and Nutt, D.J. and Honer, W.G.
DOI: 10.1371/journal.pone.0079754
2013Management of Medication-Related Cardiometabolic Risk in Patients with Severe Mental Illness
Current Cardiovascular Risk Reports
Lang, D.J. and Barr, A.M. and Procyshyn, R.M.
DOI: 10.1007/s12170-013-0321-1
2013Antipsychotic polypharmacy increases metabolic dysregulation in female rats
Experimental and Clinical Psychopharmacology
Boyda, H.N. and Procyshyn, R.M. and Tse, L. and Xu, J. and Jin, C. and Wong, D. and Pang, C.C. and Honer, W.G. and Barr, A.M.
DOI: 10.1037/a0031228
2013A retrospective study of antipsychotic drug switching in a pediatric population
BMC Psychiatry
Linton, D. and Procyshyn, R.M. and Elbe, D. and Lee, L.H.N. and Barr, A.M.
DOI: 10.1186/1471-244X-13-248
2013Predictors of persistent psychotic symptoms in persons with methamphetamine abuse receiving psychiatric treatment
Journal of Nervous and Mental Disease
Lecomte, T. and Mueser, K.T. and Macewan, W. and Thornton, A.E. and Buchanan, T. and Bouchard, V. and Goldner, E. and Brink, J. and Lang, D. and Kang, S. and Barr, A.M. and Honer, W.G.
DOI: 10.1097/NMD.0000000000000059
2013Methamphetamine-associated psychosis: A new health challenge in Iran
DARU, Journal of Pharmaceutical Sciences
Alam Mehrjerdi, Z. and Barr, A.M. and Noroozi, A.
DOI: 10.1186/2008-2231-21-30
2013Chronic benign neutropenia/agranulocytosis associated with non-clozapine antipsychotics
American Journal of Psychiatry
Vila-Rodriguez, F. and Tsang, P. and Barr, A.M.
DOI: 10.1176/appi.ajp.2013.13020215
2013Relationships among depression, PTSD, methamphetamine abuse, and psychosis
Journal of Dual Diagnosis
Lecomte, T. and Paquin, K. and Mueser, K.T. and MacEwan, G.W. and Goldner, E. and Thornton, A.E. and Brink, J. and Lang, D. and Kang, S. and Barr, A.M. and Honer, W.G.
DOI: 10.1080/15504263.2013.778930
2013Metabolic Side-Effects of the Novel Second-Generation Antipsychotic Drugs Asenapine and Iloperidone: A Comparison with Olanzapine
PLoS ONE
Boyda, H.N. and Procyshyn, R.M. and Pang, C.C.Y. and Hawkes, E. and Wong, D. and Jin, C.H. and Honer, W.G. and Barr, A.M.
DOI: 10.1371/journal.pone.0053459
2013Effects of chronic exercise and treatment with the antipsychotic drug olanzapine on hippocampal volume in adult female rats
Neuroscience
Barr, A.M. and Wu, C.H. and Wong, C. and Hercher, C. and Töpfer, E. and Boyda, H.N. and Procyshyn, R.M. and Honer, W.G. and Beasley, C.L.
DOI: 10.1016/j.neuroscience.2013.10.010
2013Antipsychotic and psychostimulant drug combination therapy in attention deficit/hyperactivity and disruptive behavior disorders: A systematic review of efficacy and tolerability
Current Psychiatry Reports
Linton, D. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1007/s11920-013-0355-6
2013Much of late life cognitive decline is not due to common neurodegenerative pathologies.
Annals of neurology
Boyle, P.A. and Wilson, R.S. and Yu, L. and Barr, A.M. and Honer, W.G. and Schneider, J.A. and Bennett, D.A.
2013Methamphetamine use: A comprehensive review of molecular, preclinical and clinical findings
Drug and Alcohol Dependence
Panenka, W.J. and Procyshyn, R.M. and Lecomte, T. and MacEwan, G.W. and Flynn, S.W. and Honer, W.G. and Barr, A.M.
DOI: 10.1016/j.drugalcdep.2012.11.016
2013Increased expression of glial fibrillary acidic protein in prefrontal cortex in psychotic illness
Schizophrenia Research
Feresten, A.H. and Barakauskas, V. and Ypsilanti, A. and Barr, A.M. and Beasley, C.L.
DOI: 10.1016/j.schres.2013.07.024
2013Pharmacological risk factors for delirium after cardiac surgery: a review.
Current neuropharmacology
Tse L and Schwarz SK and Bowering JB and Moore RL and Burns KD and Richford CM and Osborn JA and Barr AM
DOI: 10.2174/157015912803217332
PubMed: 23449337
09/2012Pharmacological risk factors for delirium after cardiac surgery: A review
Current Topics in Medicinal Chemistry
Tse, L. and Schwarz, S.K.W. and Bowering, J.B. and Moore, R.L. and Burns, K.D. and Richford, C.M. and Osborn, J.A. and Barr, A.M.
2012Intermittent treatment with olanzapine causes sensitization of the metabolic side-effects in rats
Neuropharmacology
Boyda, H.N. and Procyshyn, R.M. and Tse, L. and Wong, D. and Pang, C.C. and Honer, W.G. and Barr, A.M.
DOI: 10.1016/j.neuropharm.2011.02.019
2012Differential effects of 3 classes of antidiabetic drugs on olanzapine-induced glucose dysregulation and insulin resistance in female rats
Journal of Psychiatry and Neuroscience
Boyda, H.N. and Procyshyn, R.M. and Tse, L. and Hawkes, E. and Jin, C.H. and Pang, C.C.Y. and Honer, W.G. and Barr, A.M.
DOI: 10.1503/jpn.110140
2012Synaptic protein deficits are associated with dementia irrespective of extreme old age
Neurobiology of Aging
Schnaider Beeri, M. and Haroutunian, V. and Schmeidler, J. and Sano, M. and Fam, P. and Kavanaugh, A. and Barr, A.M. and Honer, W.G. and Katsel, P.
DOI: 10.1016/j.neurobiolaging.2011.08.017
2012Cardiovascular side-effects of antipsychotic drugs: The role of the autonomic nervous system
Pharmacology and Therapeutics
Leung, J.Y.T. and Barr, A.M. and Procyshyn, R.M. and Honer, W.G. and Pang, C.C.Y.
DOI: 10.1016/j.pharmthera.2012.04.003
2012Adverse events associated with switching antipsychotics
Journal of Psychiatry and Neuroscience
Su, J. and Barr, A.M. and Procyshyn, R.M.
DOI: 10.1503/jpn.110096
2012Cognitive reserve, presynaptic proteins and dementia in the elderly
Translational Psychiatry
Honer, W.G. and Barr, A.M. and Sawada, K. and Thornton, A.E. and Morris, M.C. and Leurgans, S.E. and Schneider, J.A. and Bennett, D.A.
DOI: 10.1038/tp.2012.38
2012Attention deficits in chronic methamphetamine users as a potential target for enhancing treatment efficacy
Basic and Clinical Neuroscience
Mehrjerdi, Z.A. and Noroozi, A. and Barr, A.M. and Ekhtiari, H.
2012Antipsychotic medications: Linking receptor antagonism to neuropsychological functioning in first episode psychosis
Journal of the International Neuropsychological Society
Baitz, H.A. and Thornton, A.E. and Procyshyn, R.M. and Smith, G.N. and MacEwan, G.W. and Kopala, L.C. and Barr, A.M. and Lang, D.J. and Honer, W.G.
DOI: 10.1017/S1355617712000343
2012Co-occurring psychosis, substance related disorders, and viral infection in a socially disadvantaged population
International Clinical Psychopharmacology
Fidel Vila-Rodriguez and G.W. MacEwan and Alasdair Barr and R.M. Procyshyn and Julio Montaner and Donna Lang and A.T. Vertinsky and M. Krajden and Allen Thornton and Geoff Smith and Michael Krausz and William Honer
DOI: 10.1097/01.yic.0000405804.51250.37
09/2011Excessive antipsychotic dosing in a canadian outpatient population
Psychiatric Services
Barr, A.M. and Panenka, W.J. and Honer, W.G. and Khara, S. and Procyshyn, R.M.
DOI: 10.1176/ps.62.6.pss6206_0682a
2011Anterior internal capsule volumes increase in patients with schizophrenia switched from typical antipsychotics to olanzapine
Journal of Psychopharmacology
Goghari, V.M. and Lang, D.J. and Khorram, B. and Götz, J. and Vandorpe, R.A. and Smith, G.N. and Kopala, L.C. and Barr, A.M. and Honer, W.G.
DOI: 10.1177/0269881110363314
2011Withdrawal
Neuromethods
Barr, A.M. and Boyda, H.N. and Procyshyn, R.M.
DOI: 10.1007/978-1-60761-934-5_16
2011A comparison of antipsychotic drug-defined daily doses versus chlorpromazine equivalent doses in patients with or without extrapyramidal motor symptoms
Journal of Clinical Psychopharmacology
Barr, A.M. and Honer, W.G. and Johnson, J.L. and Wu, T.K.Y. and Procyshyn, R.M.
DOI: 10.1097/JCP.0b013e3181fab7ca
2010A parametric study of the acute effects of antipsychotic drugs on glucose sensitivity in an animal model
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Boyda, H.N. and Tse, L. and Procyshyn, R.M. and Wong, D. and Wu, T.K.Y. and Pang, C.C. and Barr, A.M.
DOI: 10.1016/j.pnpbp.2010.04.024
2010A Novel mechanism and treatment target for presynaptic abnormalities in specific striatal regions in schizophrenia
Neuropsychopharmacology
Barakauskas, V.E. and Beasley, C.L. and Barr, A.M. and Ypsilanti, A.R. and Li, H.-Y. and Thornton, A.E. and Wong, H. and Rosokilja, G. and Mann, J.J. and Mancevski, B. and Jakovski, Z. and Davceva, N. and Ilievski, B. and Dwork, A.J. and Falkai, P. and Honer, W.G.
DOI: 10.1038/npp.2009.228
2010Preclinical models of antipsychotic drug-induced metabolic side effects
Trends in Pharmacological Sciences
Boyda, H.N. and Tse, L. and Procyshyn, R.M. and Honer, W.G. and Barr, A.M.
DOI: 10.1016/j.tips.2010.07.002
2010Persistent antipsychotic polypharmacy and excessive dosing in the community psychiatric treatment setting: A review of medication profiles in 435 Canadian outpatients
Journal of Clinical Psychiatry
Procyshyn, R.M. and Honer, W.G. and Wu, T.K.Y. and Ko, R.W.Y. and McIsaac, S.A. and Young, A.H. and Johnson, J.L. and Barr, A.M.
DOI: 10.4088/JCP.08m04912gre
2010Smoking cessation interventions among individuals in methadone maintenance: A brief review
Journal of Substance Abuse Treatment
Okoli, C.T.C. and Khara, M. and Procyshyn, R.M. and Johnson, J.L. and Barr, A.M. and Greaves, L.
DOI: 10.1016/j.jsat.2009.10.001
2010Profiles of individuals seeking psychiatric help for psychotic symptoms linked to methamphetamine abuse - Baseline results from the MAPS (methamphetamine and psychosis study)
Mental Health and Substance Use: Dual Diagnosis
Lecomte, T. and Mueser, K.T. and MacEwan, W.G. and Laferriere-Simard, M.-C. and Thornton, A.E. and Buchanan, T. and Goldner, E. and Brink, J. and Ehmann, T.S. and Lang, D. and Kang, S. and Barr, A.M. and Honer, W.G.
DOI: 10.1080/17523281.2010.504645
2010Medication errors in psychiatry: A comprehensive review
CNS Drugs
Procyshyn, R.M. and Barr, A.M. and Brickell, T. and Honer, W.G.
DOI: 10.2165/11533710-000000000-00000
2010Long-acting injectable risperidone in treatment refractory patients: A 14-week open-label pilot study
Schizophrenia Research
Procyshyn, R.M. and Barr, A.M. and Flynn, S. and Schenk, C. and Ganesan, S. and Honer, W.G.
DOI: 10.1016/j.schres.2010.07.016
2010Prenatal tobacco exposure in first-episode psychosis
Schizophrenia Research
Smith, G.N. and MacEwan, G.W. and Kopala, L.C. and Ehmann, T.S. and Good, K. and Thornton, A.E. and Neilson, H. and Lang, D.J. and Barr, A.M. and Honer, W.G.
DOI: 10.1016/j.schres.2010.01.004
2010Effect of hypertriglyceridemia on the pharmacokinetics and blood-brain barrier penetration of clozapine and norclozapine following administration to rats
European Neuropsychopharmacology
Gershkovich, P. and Sivak, O. and Sharma, A. and Barr, A.M. and Procyshyn, R. and Wasan, K.M.
DOI: 10.1016/j.euroneuro.2010.01.002
2010Effects of sub-chronic clozapine and haloperidol administration on brain lipid levels
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Barakauskas, V.E. and Ypsilanti, A.R. and Barr, A.M. and Innis, S.M. and Honer, W.G. and Beasley, C.L.
DOI: 10.1016/j.pnpbp.2010.03.010
2010A translational research approach to poor treatment response in patients with schizophrenia: clozapine-antipsychotic polypharmacy.
Journal of psychiatry & neuroscience : JPN
Honer WG and Procyshyn RM and Chen EY and MacEwan GW and Barr AM
PubMed: 19949719
11/2009Cannabis and Psychosis
Visions: BC's Mental Health and Substance Use Journal
05/2009Delirium after cardiac surgery: A retrospective case-control study of incidence and risk factors in a Canadian sample
British Columbia Medical Journal
Burns MD FRCPC, K.D. and Jenkins MD, W. and Yeh BSc, D. and Procyshyn PharmD, R.M. and Schwarz MD FRCPC, S.K.W. and Honer MD FRCPC, W.G. and Barr M. Barr, A.M.
2009Role of estradiol withdrawal in 'anhedonic' sucrose consumption: A model of postpartum depression
Physiology and Behavior
Green, A.D. and Barr, A.M. and Galea, L.A.M.
DOI: 10.1016/j.physbeh.2009.02.020
2009Impairment of memory consolidation by galanin correlates with in vivo inhibition of both LTP and CREB phosphorylation
Neurobiology of Learning and Memory
Kinney, J.W. and Sanchez-Alavez, M. and Barr, A.M. and Criado, J.R. and Crawley, J.N. and Behrens, M.M. and Henriksen, S.J. and Bartfai, T.
DOI: 10.1016/j.nlm.2009.06.005
2009Predictors of starting to smoke cigarettes in patients with first episode psychosis
Schizophrenia Research
Smith, G.N. and Wong, H. and MacEwan, G.W. and Kopala, L.C. and Ehmann, T.S. and Thornton, A.E. and Lang, D.J. and Barr, A.M. and Procyshyn, R. and Austin, J.C. and Flynn, S.W. and Honer, W.G.
DOI: 10.1016/j.schres.2008.12.013
2009A translational research approach to poor treatment response in patients with schizophrenia: Clozapine-antipsychotic polypharmacy
Journal of Psychiatry and Neuroscience
Honer, W.G. and Procyshyn, R.M. and Chen, E.Y.H. and MacEwan, G.W. and Barr, A.M.
2009Do serum lipids predict response to clozapine treatment?
Journal of Psychiatry and Neuroscience
Procyshyn, R.M. and Honer, W.G. and Barr, A.M.
2009Substance abuse as a risk factor for first episode psychosis
Schizophrenia Research
William Honer and Geoffrey Smith and Hubert Wong and Donna Lang and William Mac Ewan and Lili Kopala and Tom Ehmann and Karen Tee and Ric Procyshyn and Alasdair Barr
DOI: 10.1016/s0920-9964(08)70163-4
06/2008Heterozygous reeler mice exhibit alterations in sensorimotor gating but not presynaptic proteins
European Journal of Neuroscience
Barr, A.M. and Fish, K.N. and Markou, A. and Honer, W.G.
DOI: 10.1111/j.1460-9568.2008.06233.x
2008Self-reported motivation to smoke in schizophrenia is related to antipsychotic drug treatment
Schizophrenia Research
Barr, A.M. and Procyshyn, R.M. and Hui, P. and Johnson, J.L. and Honer, W.G.
DOI: 10.1016/j.schres.2007.11.027
2008Determination of clozapine and its metabolite, norclozapine in various biological matrices using high-performance liquid chromatography.
Drug development and industrial pharmacy
Rosland M and Szeto P and Procyshyn R and Barr AM and Wasan KM
DOI: 10.1080/03639040701484338
PubMed: 17963117
10/2007Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment.
Journal of psychiatry & neuroscience : JPN
Procyshyn RM and Wasan KM and Thornton AE and Barr AM and Chen EY and Pomarol-Clotet E and Stip E and Williams R and Macewan GW and Birmingham CL and Honer WG and Clozapine and Risperidone Enhancement Study Group
PubMed: 17823649
09/2007Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine
Molecular Psychiatry
Conti, B. and Maier, R. and Barr, A.M. and Morale, M.C. and Lu, X. and Sanna, P.P. and Bilbe, G. and Hoyer, D. and Bartfai, T.
DOI: 10.1038/sj.mp.4001897
2007Conceptual and methodological issues in the design of clinical trials of antipsychotics for the treatment of schizophrenia
CNS Drugs
Honer, W.G. and Thornton, A.E. and Sherwood, M. and MacEwan, G.W. and Ehmann, T.S. and Williams, R. and Kopala, L.C. and Procyshyn, R. and Barr, A.M.
DOI: 10.2165/00023210-200721090-00001
2007The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice
Neuropharmacology
Barr, A.M. and Fish, K.N. and Markou, A.
DOI: 10.1016/j.neuropharm.2006.11.011
2007Determination of clozapine and its metabolite, norclozapine in various biological matrices using high-performance liquid chromatography
Drug Development and Industrial Pharmacy
Rosland, M. and Szeto, P. and Procyshyn, R. and Barr, A.M. and Wasan, K.M.
DOI: 10.1080/03639040701484338
2007A longitudinal study on the effects of typical versus atypical antipsychotic drugs on hippocampal volume in schizophrenia
Schizophrenia Research
Panenka, W.J. and Khorram, B. and Barr, A.M. and Smith, G.N. and Lang, D.J. and Kopala, L.C. and Vandorpe, R.A. and Honer, W.G.
DOI: 10.1016/j.schres.2007.05.002
2007Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity
Journal of Neurochemistry
Hill, M.N. and Barr, A.M. and Ho, W.-S.V. and Carrier, E.J. and Gorzalka, B.B. and Hillard, C.J.
DOI: 10.1111/j.1471-4159.2007.04688.x
2007Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment
Journal of Psychiatry and Neuroscience
Procyshyn, R.M. and Wasan, K.M. and Thornton, A.E. and Barr, A.M. and Chen, E.Y.H. and Pomarol-Clotet, E. and Stip, E. and Williams, R. and MacEwan, G.W. and Birmingham, C.L. and Honer, W.G.
2007Altered Performance of Reelin-Receptor ApoER2 Deficient Mice on Spatial Tasks Using the Barnes Maze
Behavioral Neuroscience
Barr, A.M. and MacLaurin, S.A. and Semenova, S. and Fish, K.N. and Markou, A.
DOI: 10.1037/0735-7044.121.5.1101
2007Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats
Neuropharmacology
Barr, A.M. and Powell, S.B. and Markou, A. and Geyer, M.A.
DOI: 10.1016/j.neuropharm.2006.04.004
2006The need for speed: An update on methamphetamine addiction
Journal of Psychiatry and Neuroscience
Barr, A.M. and Panenka, W.J. and MacEwan, G.W. and Thornton, A.E. and Lang, D.J. and Honer, W.G. and Lecomte, T.
2006Selective effects of typical antipsychotic drugs on SNAP-25 and synaptophysin in the hippocampal trisynaptic pathway
International Journal of Neuropsychopharmacology
Barr, A.M. and Young, C.E. and Phillips, A.G. and Honer, W.G.
DOI: 10.1017/S1461145705006000
2006A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests
Neuroscience Letters
Barr, A.M. and Kinney, J.W. and Hill, M.N. and Lu, X. and Biros, S. and Rebek Jr., J. and Bartfai, T.
DOI: 10.1016/j.neulet.2006.06.033
2006Relevance of presynaptic proteins to neuropsychiatric disorders
Molecular Mechanisms of Synaptogenesis
Barr, A.M. and Young, C.E. and Sawada, K. and Honer, W.G.
DOI: 10.1007/978-0-387-32562-0_27
2006Ethyl-EPA treatment improves motor dysfunction, but not neurodegeneration in the YAC128 mouse model of Huntington disease
Experimental Neurology
Van Raamsdonk, J.M. and Pearson, J. and Rogers, D.A. and Lu, G. and Barakauskas, V.E. and Barr, A.M. and Honer, W.G. and Hayden, M.R. and Leavitt, B.R.
DOI: 10.1016/j.expneurol.2005.07.021
2005Galanin receptors as novel drug targets for the treatment of depression and anxiety
Drug Development Research
Lu, X. and Barr, A.M. and Bartfai, T.
DOI: 10.1002/ddr.20026
2005Hippocampal complexin proteins and cognitive dysfunction in schizophrenia
Archives of General Psychiatry
Sawada, K. and Barr, A.M. and Nakamura, M. and Arima, K. and Young, C.E. and Dwork, A.J. and Falkai, P. and Phillips, A.G. and Honer, W.G.
DOI: 10.1001/archpsyc.62.3.263
2005Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity
Journal of Neurochemistry
Conti, B. and Sugama, S. and Lucero, J. and Winsky-Sommerer, R. and Wirz, S.A. and Maher, P. and Andrews, Z. and Barr, A.M. and Morale, M.C. and Paneda, C. and Pemberton, J. and Gaidarova, S. and Behrens, M.M. and Beal, F. and Sanna, P.P. and Horvath, T.L. and Bartfai, T.
DOI: 10.1111/j.1471-4159.2005.03052.x
2005A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus
Proceedings of the National Academy of Sciences of the United States of America
Lu, X. and Barr, A.M. and Kinney, J.W. and Sanna, P. and Conti, B. and Behrens, M.M. and Bartfai, T.
DOI: 10.1073/pnas.0408891102
2005Prenatal ethanol exposure in rats decreases levels of complexin proteins in the frontal cortex
Alcoholism: Clinical and Experimental Research
Barr, A.M. and Hofmann, C.E. and Phillips, A.G. and Weinberg, J. and Honer, W.G.
DOI: 10.1097/01.alc.0000187806.68957.0a
2005Psychostimulant withdrawal as an inducing condition in animal models of depression
Neuroscience and Biobehavioral Reviews
Barr, A.M. and Markou, A.
DOI: 10.1016/j.neubiorev.2005.03.012
2005The Selective Serotonin-2A Receptor Antagonist M100907 Reverses Behavioral Deficits in Dopamine Transporter Knockout Mice
Neuropsychopharmacology
Barr, A.M. and Lehmann-Masten, V. and Paulus, M. and Gainetdinov, R.R. and Caron, M.G. and Geyer, M.A.
DOI: 10.1038/sj.npp.1300343
2004Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine treatment
Neuroscience
Sugama, S. and Wirz, S.A. and Barr, A.M. and Conti, B. and Bartfai, T. and Shibasaki, T.
DOI: 10.1016/j.neuroscience.2004.07.020
2004High frequency of TNF alleles -238A and -376A in individuals from northern Sardinia
Cytokine
Wirz, S.A. and Morale, M.C. and Marchetti, B. and Barr, A.M. and Sotgiu, S. and Rosati, G. and Pugliatti, M. and Sanna, M.V. and Giliberto, O. and Bartfai, T. and Conti, B.
DOI: 10.1016/j.cyto.2004.02.006
2004Abnormalities of presynaptic protein CDCrel-1 in striatum of rats reared in social isolation: Relevance to neural connectivity in schizophrenia
European Journal of Neuroscience
Barr, A.M. and Young, C.E. and Sawada, K. and Trimble, W.S. and Phillips, A.G. and Honer, W.G.
DOI: 10.1111/j.0953-816X.2004.03457.x
2004Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests
Proceedings of the National Academy of Sciences of the United States of America
Bartfai, T. and Lu, X. and Badie-Mahdavi, H. and Barr, A.M. and Mazaratit, A. and Hua, X.-Y. and Yaksh, T. and Haberhauer, G. and Ceide, S.C. and Trembleau, L. and Somogyi, L. and Kröck, L. and Rebek Jr., J.
DOI: 10.1073/pnas.0403802101
2004Role of integrin-linked kinase in nerve growth factor-stimulated neurite outgrowth
Journal of Neuroscience
Mills, J. and Digicaylioglu, M. and Legg, A.T. and Young, C.E. and Young, S.S. and Barr, A.M. and Fletcher, L. and O'Connor, T.P. and Dedhar, S.
DOI: 10.1523/jneurosci.23-05-01638.2003
2003Tolerance to the anhedonic effects of lipopolysaccharide is associated with changes in syntaxin immunoreactivity in the nucleus accumbens
International Journal of Neuropsychopharmacology
Barr, A.M. and Song, C. and Sawada, K. and Young, C.E. and Honer, W.G. and Phillips, A.G.
DOI: 10.1017/S146114570200319X
2003Effects of amisulpride on consummatory negative contrast.
Behavioural pharmacology
Genn RF and Barr AM and Phillips AG
DOI: 10.1097/01.fbp.0000046508.84018.85
PubMed: 12478217
12/2002Increased successive negative contrast in rats withdrawn from an escalating-dose schedule of d-amphetamine
Pharmacology Biochemistry and Behavior
Alasdair M. Barr and Anthony G. Phillips
DOI: 10.1016/s0091-3057(01)00664-5
01/2002A 'crash' course on psychostimulant withdrawal as a model of depression
Trends in Pharmacological Sciences
Barr, A.M. and Markou, A. and Phillips, A.G.
DOI: 10.1016/S0165-6147(02)02086-2
2002High levels of estradiol impair spatial performance in the Morris water maze and increase 'depressive-like' behaviors in the female meadow vole
Physiology and Behavior
Galea, L.A.M. and Lee, T.T.-Y. and Kostaras, X. and Sidhu, J.A. and Barr, A.M.
DOI: 10.1016/S0031-9384(02)00849-1
2002Repeated electroconvulsive shock attenuates the depressive-like effects of d-amphetamine withdrawal on brain reward function in rats
Psychopharmacology
Barr, A.M. and Zis, A.P. and Phillips, A.G.
DOI: 10.1007/s002130100906
2002Altered immunoreactivity of complexin protein in prefrontal cortex in severe mental illness
Molecular Psychiatry
Sawada, K. and Young, C.E. and Barr, A.M. and Longworth, K. and Takahashi, S. and Arango, V. and Mann, J.J. and Dwork, A.J. and Falkai, P. and Phillips, A.G. and Honer, W.G.
DOI: 10.1038/sj.mp.4000978
2002Exposure to repeated, intermittent d-amphetamine induces sensitization of HPA axis to a subsequent stressor
Neuropsychopharmacology
Barr, A.M. and Hofmann, C.E. and Weinberg, J. and Phillips, A.G.
DOI: 10.1016/S0893-133X(01)00308-6
2002Estradiol alleviates depressive-like symptoms in a novel animal model of post-partum depression
Behavioural Brain Research
Galea, L.A.M and Wide, J.K. and Barr, A.M.
DOI: 10.1016/S0166-4328(01)00170-X
2001Paradoxical effects of chronic corticosterone on forced swim behaviours in aged male and female rats
European Journal of Pharmacology
Brotto, L.A. and Gorzalka, B.B. and Barr, A.M.
DOI: 10.1016/S0014-2999(01)01148-7
2001The development of an animal model of depression : a focus on anhedonia
The University of British Columbia
DOI: 10.14288/1.0090835
2001Sex differences in forced-swim and open-field test behaviours after chronic administration of melatonin
European Journal of Pharmacology
Brotto, L.A. and Barr, A.M. and Gorzalka, B.B.
DOI: 10.1016/S0014-2999(00)00491-X
2000Chronic corticosterone enhances the rewarding effect of hypothalamic self-stimulation in rats
Brain Research
Barr, A.M. and Brotto, L.A. and Phillips, A.G.
DOI: 10.1016/S0006-8993(00)02652-4
2000Effects of withdrawal from an escalating dose schedule of d-amphetamine on Sexual behavior in the male rat
Pharmacology Biochemistry and Behavior
Barr, A.M. and Fiorino, D.F. and Phillips, A.G.
DOI: 10.1016/S0091-3057(99)00156-2
1999Withdrawal following repeated exposure to d-amphetamine decreases responding for a sucrose solution as measured by a progressive ratio schedule of reinforcement
Psychopharmacology
Barr, A.M. and Phillips, A.G.
DOI: 10.1007/s002130050812
1999Chronic mild stress has no effect on responding by rats for sucrose under a progressive ratio schedule
Physiology and Behavior
Barr, A.M. and Phillips, A.G.
DOI: 10.1016/S0031-9384(98)00060-2
1998Stimulation of the Ventral Subiculum of the Hippocampus Evokes Glutamate Receptor-mediated Changes in Dopamine Efflux in the Rat Nucleus Accumbens
European Journal of Neuroscience
Charles D. Blaha and Charles R. Yang and Stan B. Floresco and Alasdair M. Barr and Anthony G. Phillips
DOI: 10.1111/j.1460-9568.1997.tb01441.x
05/1997Effects of chronic mild stress on motivation for sucrose: Mixed messages
Psychopharmacology
Phillips, A.G. and Barr, A.M.
DOI: 10.1007/s002130050469
1997 - Research
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Research Group Members
Hannah Akhlaghi, Volunteer
Jodi Anderson, Graduate Research Assistant
David Kim, Doctoral Student
Su Lin Lim, Research Assistant
Rachel McLellan-Carich
Michiko Opek, Volunteer
Livleen Randhawa, Volunteer
Anna Xiao, Volunteer Research Assistant
Michael Zhang, INSPIRE Volunteer
Congratulations CIHR Project Grant Recipients!
Congratulations to the BC Children's and BC Women's investigators who were awarded funding through the highly competitive Canadian Institutes of Health Research (CIHR) Project Grant Fall 2019 competition.
