Overview

Dr. Edmond Chan is a clinical investigator at the BCCH Research Institute and his research interests are in food allergy and eosinophilic esophagitis (EoE). As of Dec 2021, he has 148 peer-reviewed publications. Multi-centre national and international research studies include an oral cow’s milk immunotherapy clinical trial, several epicutaneous peanut immunotherapy clinical trials, national food allergy registries (peanut, seafood, etc), a national anaphylaxis registry, CHILD study birth cohort peanut allergy outcomes, national oral food challenge barriers & solutions, Health Canada study of emerging food allergens, national/international early peanut introduction implementation studies, and use of Epitope Mapping for food allergy diagnosis.

Local (including provincial) projects that have national extensions include our food allergy E-Health tool (Allergycheck.ca), food allergy-related anxiety, confidence with using epinephrine autoinjectors, allergy outcomes among premature infants, and selective/cost-effective use of component resolved testing for food allergy diagnosis. EoE specific projects together with Gastroenterology (Dr Vishal Avinashi) include: our unique EoE registry, EoE Biomarkers and epigenetic markers, the interaction between oral immunotherapy and EoE, organoids, EoEHSS (Histology scoring system), and T-cell assays for food triggers of EoE (and FPIES).

QI (Quality improvement) has been focused primarily on real-world pre-school peanut oral immunotherapy, which has expanded to multiple foods, cost-effectiveness, adherence (e.g. text messaging), virtual care, milk/egg ladders, and sublingual immunotherapy in older children. He has been an author on multiple clinical practice guidelines including CPS/CSACI and NIAID/National Institutes of Health) food allergy prevention guidelines, CSACI oral immunotherapy guidelines, and AGA/Joint Task Force EoE guidelines.

Publications

Food-allergy-specific anxiety and distress in parents of children with food allergy: A systematic review
Pediatric Allergy and Immunology
Clara Westwell-Roper and Sharon To and Gordan Andjelic and Cynthia Lu and Boyee Lin and Lianne Soller and Edmond S. Chan and S. Evelyn Stewart
DOI: 10.1111/pai.13695
01/2022

Canadian parent perceptions of oral food challenges: A qualitative analysis
Pediatric Allergy and Immunology
Natasha Correa and Jennifer L. P. Protudjer and Elaine Hsu and Lianne Soller and Edmond S. Chan and Harold Kim and Samira Jeimy
DOI: 10.1111/pai.13698
01/2022

Application of the Eosinophilic Esophagitis Histology Scoring System Grade Scores in Patients at British Columbia Children’s Hospital
Fetal and Pediatric Pathology
Justin Cruz and Michael A. Irvine and Vishal Avinashi and Edmond S. Chan and Bruce A. Vallance and Lianne Soller and Jonathan W. Bush
DOI: 10.1080/15513815.2022.2028950
01/2022

How to Incorporate Oral Immunotherapy into Your Clinical Practice
Current Allergy and Asthma Reports
Elissa M. Abrams and Stephanie C. Erdle and Scott B. Cameron and Lianne Soller and Edmond S. Chan
DOI: 10.1007/s11882-021-01009-8
04/2021

Early Solid Food Introduction: Role in Food Allergy Prevention and Implications for Breastfeeding
The Journal of Pediatrics
Elissa M. Abrams and Matthew Greenhawt and David M. Fleischer and Edmond S. Chan
DOI: 10.1016/j.jpeds.2017.01.053
05/2017

Utility of Ara h 2 sIgE levels to predict peanut allergy in Canadian children
The Journal of Allergy and Clinical Immunology: In Practice
Sara H. Leo and John M. Dean and Benjamin Jung and Boris Kuzeljevic and Edmond S. Chan
DOI: 10.1016/j.jaip.2015.04.001
11/2015

Characterization of ethnicity among children with eosinophilic esophagitis in British Columbia, Canada
The Journal of Allergy and Clinical Immunology: In Practice
Timothy Teoh and Chris Koo and Vishal Avinashi and Edmond S. Chan
DOI: 10.1016/j.jaip.2015.04.016
09/2015

Consensus Communication on Early Peanut Introduction and Prevention of Peanut Allergy in High-Risk Infants
Pediatr Dermatol
David M. Fleischer and Scott Sicherer and Matthew Greenhawt and Dianne Campbell and Edmond Chan and Antonella Muraro and Susanne Halken and Yitzhak Katz and Motohiro Ebisawa and Lawrence Eichenfield and Hugh Sampson and Gideon Lack and George Du Toit and Graham Roberts and Henry Bahnson and Mary Feeney and Jonathan Hourihane and Jonathan Spergel and Michael Young and Amal As'aad and Katrina Allen and Susan Prescott and Sandeep Kapur and Hirohisa Saito and Ioana Agache and Cezmi A. Akdis and Hasan Arshad and Kirsten Beyer and Anthony Dubois and Philippe Eigenmann and Monserrat Fernandez-Rivas and Kate Grimshaw and Karin Hoffman-Sommergruber and Arne Host and Susanne Lau and Liam O'Mahony and Clare Mills and Nikolaus Papadopoulos and Carina Venter and Nancy Agmon-Levin and Aaron Kessel and Richard Antaya and Beth Drolet and Lanny Rosenwasser
DOI: 10.1111/pde.12685
09/2015

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants
World Allergy Organ J
David M. Fleischer and FOR THE LEAP TRIAL TEAM and Scott Sicherer and Matthew Greenhawt and Dianne Campbell and Edmond S. Chan and Antonella Muraro and Susanne Halken and Yitzhak Katz and Motohiro Ebisawa and Lawrence Eichenfield and Hugh Sampson and SECONDARY CONTRIBUTORS
DOI: 10.1186/s40413-015-0076-x
08/2015

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants
Journal of Allergy and Clinical Immunology
David M. Fleischer and Scott Sicherer and Matthew Greenhawt and Dianne Campbell and Edmond Chan and Antonella Muraro and Susanne Halken and Yitzhak Katz and Motohiro Ebisawa and Lawrence Eichenfield and Hugh Sampson and Gideon Lack and George Du Toit and Graham Roberts and Henry Bahnson and Mary Feeney and Jonathan Hourihane and Jonathan Spergel and Michael Young and Amal As'aad and Katrina Allen and Susan Prescott and Sandeep Kapur and Hirohisa Saito and Ioana Agache and Cezmi A. Akdis and Hasan Arshad and Kirsten Beyer and Anthony Dubois and Philippe Eigenmann and Monserrat Fernandez-Rivas and Kate Grimshaw and Karin Hoffman-Sommergruber and Arne Host and Susanne Lau and Liam O'Mahony and Clare Mills and Nikolaus Papadopoulos and Carina Venter and Nancy Agmon-Levin and Aaron Kessel and Richard Antaya and Beth Drolet and Lanny Rosenwasser
DOI: 10.1016/j.jaci.2015.06.001
08/2015

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants
Annals of Allergy, Asthma & Immunology
David M. Fleischer and Scott Sicherer and Matthew Greenhawt and Dianne Campbell and Edmond Chan and Antonella Muraro and Susanne Halken and Yitzhak Katz and Motohiro Ebisawa and Lawrence Eichenfield and Hugh Sampson and Gideon Lack and George Du Toit and Graham Roberts and Henry Bahnson and Mary Feeney and Jonathan Hourihane and Jonathan Spergel and Michael Young and Amal As'aad and Katrina Allen and Susan Prescott and Sandeep Kapur and Hirohisa Saito and Ioana Agache and Cezmi A. Akdis and Hasan Arshad and Kirsten Beyer and Anthony Dubois and Philippe Eigenmann and Monserrat Fernandez-Rivas and Kate Grimshaw and Karin Hoffman-Sommergruber and Arne Host and Susanne Lau and Liam O'Mahony and Clare Mills and Nikolaus Papadopoulos and Carina Venter and Nancy Agmon-Levin and Aaron Kessel and Richard Antaya and Beth Drolet and Lanny Rosenwasser
DOI: 10.1016/j.anai.2015.06.001
08/2015

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants
Allergy Asthma Clin Immunol
David M. Fleischer and FOR THE LEAP TRIAL TEAM and Scott Sicherer and Matthew Greenhawt and Dianne Campbell and Edmond S. Chan and Antonella Muraro and Susanne Halken and Yitzhak Katz and Motohiro Ebisawa and Lawrence Eichenfield and Hugh Sampson and SECONDARY CONTRIBUTORS
DOI: 10.1186/s13223-015-0087-8
08/2015

Accidental exposures to peanut in a large cohort of Canadian children with peanut allergy
Clin Transl Allergy
Sabrine Cherkaoui and Moshe Ben-Shoshan and Reza Alizadehfar and Yuka Asai and Edmond Chan and Stephen Cheuk and Greg Shand and Yvan St-Pierre and Laurie Harada and Mary Allen and Ann Clarke
DOI: 10.1186/s13601-015-0055-x
04/2015

CSACI position statement: systemic effect of inhaled corticosteroids on adrenal suppression in the management of pediatric asthma
Allergy, Asthma & Clinical Immunology
Karine Issa-El-Khoury and Harold Kim and Edmond S Chan and Tim Vander Leek and Francisco Noya
DOI: 10.1186/s13223-015-0075-z
2015

Clinical Characteristics Of Seafood Allergy In Canadian Children
Journal of Allergy and Clinical Immunology
Victoria Cook and Edmond S. Chan and Ann Elaine Clarke and Greg Shand and Moshe Ben-Shoshan
DOI: 10.1016/j.jaci.2013.12.727
02/2014

IgE Mediated allergy to wheat in a child with celiac disease
Allergy, Asthma & Clinical Immunology
Tiffany Wong and Edmond S Chan
DOI: 10.1186/1710-1492-10-s1-a37
2014

Dietary exposures and allergy prevention in high-risk infants: a joint position statement of the Canadian Society of Allergy and Clinical Immunology and the Canadian Paediatric Society
Allergy, Asthma & Clinical Immunology
Edmond S Chan and Carl Cummings and Adelle Atkinson and Zave Chad and Marie-Josée Francoeur and Linda Kirste and Douglas Mack and Marie-Noël Primeau and Timothy K Vander Leek and Wade TA Watson
DOI: 10.1186/1710-1492-10-45
2014

Epinephrine auto injector administration by parents or patients for anaphylaxis during supervised oral food challenges and assessment of confidence
Allergy, Asthma & Clinical Immunology
Ingrid Baerg and Angela Alexander and Tiffany Wong and Timothy Teoh and Kyla Hildebrand and Sara Leo and Joanne Yeung and John Dean and Edmond Chan
DOI: 10.1186/1710-1492-10-s2-a2
2014

IgE-Mediated allergy to wheat in a child with celiac disease – a case report
Allergy, Asthma & Clinical Immunology
Tiffany Wong and Hin Ko and Edmond S Chan
DOI: 10.1186/1710-1492-10-56
2014

Delayed Introduction of Food and Effect On Incidence of Food Allergy in a Population At High Risk for Atopy: The Canadian Asthma Primary Prevention Study (CAPPS)
Journal of Allergy and Clinical Immunology
Tiffany Wong and Moira Chan-Yeung and Roxanne Rousseau and Anne Dybuncio and Anita L. Kozyrskyj and Clare Ramsey and Allan Becker and Edmond S. Chan
DOI: 10.1016/j.jaci.2012.12.1013
02/2013

Egg-allergic patients can be safely vaccinated against influenza
Journal of Allergy and Clinical Immunology
Anne Des Roches and Louis Paradis and Remi Gagnon and Chantal Lemire and Philippe Bégin and Stuart Carr and Edmond S. Chan and Jean Paradis and Lyne Frenette and Manale Ouakki and Mélanie Benoît and Gaston De Serres
DOI: 10.1016/j.jaci.2012.07.046
11/2012

CSACI Position statement on the testing of food-specific IgG
Allergy, Asthma & Clinical Immunology
Stuart Carr and Edmond Chan and Elana Lavine and William Moote
DOI: 10.1186/1710-1492-8-12
2012

Allergic symptoms after pandemic influenza vaccination rarely mediated by vaccine-specific IgE
Journal of Allergy and Clinical Immunology
Isabelle Rouleau and Gaston De Serres and Jean Philippe Drolet and Devi Banerjee and Chantal Lemire and Andrew Moore and Louis Paradis and Reza Alizadhefar and Anne Des Roches and Edmond S. Chan and Donald Stark and Mélanie Benoit and Danuta M. Skowronski
DOI: 10.1016/j.jaci.2012.07.019
2012

Outcome of diagnostic intervention predicts health-related quality of life scores among children with food allergy
Allergy, Asthma & Clinical Immunology
Linda Kirste and Tim K Takaro and Boris Kuzeljevic and Tiffany Wong and Edmond S Chan
DOI: 10.1186/1710-1492-8-s1-a9
2012

What are the beliefs of pediatricians and dietitians regarding complementary food introduction to prevent allergy?
Allergy, Asthma & Clinical Immunology
Sara Leo and John Dean and Edmond S Chan
DOI: 10.1186/1710-1492-8-3
2012

What are the beliefs of pediatricians and dietitians regarding complementary food introduction to prevent allergy?
Allergy, Asthma & Clinical Immunology
Sara H Leo and John M Dean and Edmond S Chan
DOI: 10.1186/1710-1492-7-s2-a3
2011

Serum sickness-like reaction associated with meropenem in a 3-year old child
Allergy, Asthma & Clinical Immunology
Sara H Leo and Edmond S Chan
DOI: 10.1186/1710-1492-6-s2-p31
2010

Safety of H1N1 and seasonal influenza vaccines in egg allergic patients in British Columbia
Allergy, Asthma & Clinical Immunology
Sara H Leo and John Dean and Edmond S Chan
DOI: 10.1186/1710-1492-6-s2-p4
2010

Epinephrine for the out-of-hospital (first-aid) treatment of anaphylaxis in infants: Is the ampule/syringe/needle method practical?
Journal of Allergy and Clinical Immunology
F.Estelle R. Simons and Edmond S. Chan and Xiaochen Gu and Keith J. Simons
DOI: 10.1067/mai.2001.119916
2001

Research

Epicutaneous Peanut Immunotherapy Clinical Trials
PEPITES, PEOPLE, REALISE, EPITOPE Clinical Trials

Pre-school Peanut Oral Immunotherapy
Evaluation of real world safety outcomes for pre-school peanut oral immunotherapy

Grants

CIHR, Food allergy tolerance studies/Cow’s milk oral immunotherapy, $500,000, 11/2013 to 11/2018, Co-investigator

Honours & Awards

Clinical Faculty Award for Excellence in Clinical Teaching, UBC Faculty of Medicine - 2012

Family Centered Care Award, Partners in Care, BC Children's Hospital and BC Children's Hospital Foundation - 2012

UBC Department of Pediatrics, Ivory Tower Award, in recognition of contributions to promoting resident research and academic medicine - 2014

Research Group Members

Ingrid Baerg, Research Nurse
Michelle Bobyn, Allergy Research Nurse
Rishma Chooniedass, Food Allergy Educator
Victoria Cook, Allergy Fellow
Lynn Cunada, Clinical Research Nurse
Ravinder Dhaliwal
Deanna Douglas, Junior Research Assistant
Jennifer Fortkamp, Allergy Clinic Research Secretary
Tracy Gonzalez, Research Nurse
Kelly Morrison, Research Nurse
Linda Pringle, Research Nurse
Lianne Soller, Allergy Research Manager
Brittany Tetreault, Allergy Nurse
Sharon To
Chantelle Van Nostern
Brock Williams, Doctoral Student
Allison Wugalter, Junior Research Assistant
Ethan Zhang, Research Assistant