
A new paper published in New England Journal of Medicine details how an 18-year-old patient being treated at BC Children’s Hospital (BCCH) for a rare disease called chronic granulomatous disease (CGD) became the first person ever to receive and be cured by a gene modification treatment known as “Prime Editing.”

February 15 was International Childhood Cancer Day and to mark the occasion we spoke with Dr. Sarah Alexander, a new BCCHR investigator and pediatric oncologist at BC Children’s Hospital who specializes in some of the most common childhood cancers, including non-Hodgkin lymphoma and acute lymphoblastic leukemia (ALL).

Pediatric centres nationwide have united to launch the DECRYPT-BABYBRAIN trial, a first-of-its-kind clinical trial that uses chemotherapy delivered to the brain to avoid radiation in treating babies and young children with aggressive brain cancer. The trial has recruited its first six participants, with enrollment now open at The Hospital for Sick Children (SickKids) in Toronto,…