Cjc Pediatric and Congenital Heart Disease
Abozaid, W. and Mitra, S. and Jasani, B. and Benson, L. and Rathgeber, S.L.
DOI: 10.1016/j.cjcpc.2024.12.002Children
Campbell-Yeo, M. and Mireault, A. and Bacchini, F. and Beltempo, M. and Shah, P.S. and Alcock, L. and Comeau, J. and Dol, J. and Grant, A. and Gubbay, J. and Hughes, B. and Hundert, A. and Inglis, D. and Lalani, Y. and MacNeil, M. and Luu, T.M. and Mitra, S. and Narvey, M. and O?Brien, K. and Robeson, P. and Science, M.
DOI: 10.3390/children12020193Journal of Neonatal Perinatal Medicine
Weisz, D.E. and Thomas, L. and Ye, X.Y. and Mertens, L. and Lapointe, A. and Villeneuve, A. and Altit, G. and Lalitha, R. and Ben Fadel, N. and Jacob, G. and Louis, D. and Bhattacharya, S. and Soraisham, A. and H{\'e}bert, A. and Mitra, S. and Hyderi, A. and Ting, J.Y. and Castaldo, M. and Surak, A. and Deshpande, P. and Elsayed, Y. and Jasani, B. and Nissimov, S. and Zhu, F. and Shah, P. and Jain, A.
DOI: 10.1177/19345798251349744Cochrane Database of Systematic Reviews
Mitra, S. and Scrivens, A. and Fiander, M. and Disher, T. and Weisz, D.E.
DOI: 10.1002/14651858.CD013278.pub3Journal of the Society for Cardiovascular Angiography and Interventions
Batlivala, S.P. and Boucek, D. and Downing, T. and Head, T. and Herbert, C. and Levy, P. and Ligon, R.A. and Mitra, S. and Salavitabar, A. and Sathanandam, S. and Taggart, N. and Zablah, J. and Zahn, E. and Gordon, B.M.
DOI: 10.1016/j.jscai.2025.103866Pediatric Research
Kanagaraj, U.K. and Castaldo, M. and Braschel, M. and Harris, A. and Mitra, S.
DOI: 10.1038/s41390-025-04389-zJournal of Pediatrics
El-Naggar, W. and Mitra, S. and Abeysekera, J. and Disher, T. and Woolcott, C. and Hatfield, T. and McMillan, D. and Dorling, J.
DOI: 10.1016/j.jpeds.2024.114444JAMA Network Open
Baczynski, M. and Weisz, D. and Thomas, L. and Fevrier, S. and Castaldo, M. and Soraisham, A. and Hyderi, A. and Agarushi, R. and Bhattacharya, S. and Lalitha, R. and Sidhu, A. and Abdul Wahab, M.G. and Altit, G. and H{\'e}bert, A. and Louis, D. and Elsayed, Y. and Mitra, S. and Deshpande, P. and Kharrat, A. and Zhu, F. and Ting, J. and Yoon, E. and Shah, P.S. and Jain, A.
DOI: 10.1001/jamanetworkopen.2024.58843Journal of Obstetrics and Gynaecology Canada
Kelly, L.E. and Proulx, L. and Moss, N. and Bacchini, F. and Malham{\'e}, I. and Mitra, S. and Allegaert, K. and Dayan, N.
DOI: 10.1016/j.jogc.2025.103111Archives of Disease in Childhood: Fetal and Neonatal Edition
Mitra, S. and Whitehead, L. and Smith, K. and Maclean, B. and Nixon, R. and Veysey, A. and Campbell-Yeo, M. and Kuhle, S. and Gale, C. and Soll, R. and Dorling, J. and Johnston, B.C.
DOI: 10.1136/archdischild-2023-325445BMJ Open
Mitra, S. and Hbert, A. and Castaldo, M. and Disher, T. and El-Naggar, W. and Dhillon, S. and Alhassen, Z. and Koo, J. and Katheria, A.C. and Hyderi, A. and Kumaran, K. and Makoni, M. and Weisz, D.E. and Jain, A. and Bacchini, F. and Cameron, A. and Hatfield, T. and Dorling, J. and McNamara, P.J. and Thabane, L.
DOI: 10.1136/bmjopen-2024-087998Frontiers in Pediatrics
Campbell-Yeo, M. and Bacchini, F. and Alcock, L. and Mitra, S. and MacNeil, M. and Mireault, A. and Beltempo, M. and Bishop, T. and Campbell, D.M. and Chilcott, A. and Comeau, J.L. and Dol, J. and Grant, A. and Gubbay, J. and Hughes, B. and Hundert, A. and Inglis, D. and Lakoff, A. and Lalani, Y. and Luu, T.M. and Morton, J. and Narvey, M. and O?Brien, K. and Robeson, P. and Science, M. and Shah, P. and Whitehead, L.
DOI: 10.3389/fped.2024.1390209Journal of Perinatology
Mitra, S. and Bischoff, A.R. and Sathanandam, S. and Lakshminrusimha, S. and McNamara, P.J.
DOI: 10.1038/s41372-024-02052-9Neonatology
Bruschettini, M. and Schmlzer, G.M. and Lai, N.M. and Mitra, S. and Davis, P.G. and Soll, R.F.
DOI: 10.1159/000540604Early Human Development
Allegaert, K. and Mitra, S. and Smits, A. and Turner, M.A.
DOI: 10.1016/j.earlhumdev.2024.106136Archives of Disease in Childhood: Fetal and Neonatal Edition
Schmlzer, G.M. and Pichler, G. and Solev?g, A.L. and Law, B.H.Y. and Mitra, S. and Wagner, M. and Pfurtscheller, D. and Yaskina, M. and Cheung, P.-Y.
DOI: 10.1136/archdischild-2023-326383Cochrane Database of Systematic Reviews
MacLellan, A. and Cameron-Nola, A.J. and Cooper, C. and Mitra, S.
DOI: 10.1002/14651858.CD015424.pub2Paediatrics and Child Health Canada
Mitra, S. and Altit, G.
DOI: 10.1093/pch/pxac108Journal of Perinatology
Wright, C.J. and McCulley, D.J. and Mitra, S. and Jensen, E.A.
DOI: 10.1038/s41372-023-01697-2Cochrane Database of Systematic Reviews
Mitra, S. and de Boode, W.P. and Weisz, D.E. and Shah, P.S.
DOI: 10.1002/14651858.CD013588.pub2Acta Paediatrica, International Journal of Paediatrics
Mitra, S.
DOI: 10.1111/apa.16853Paediatrics and Child Health Canada
Mitra, S. and Altit, G.
DOI: 10.1093/pch/pxac107JAMA Network Open
Mitra, S. and Hatfield, T. and Campbell-Yeo, M. and Dorling, J. and Johnston, B.C.
DOI: 10.1001/jamanetworkopen.2023.2273Cochrane Database of Systematic Reviews
Kinoshita, M. and Del Giovane, C. and Mitra, S. and Hall, R. and Soll, R. and Bruschettini, M.
DOI: 10.1002/14651858.CD015058Cochrane Database of Systematic Reviews
Lingappan, K. and Malviya, M.N. and Pammi, M. and Mitra, S.
DOI: 10.1002/14651858.CD014862Journal of Evidence-Based Medicine
Mitra, S. and Boasquevisque, D.D.S. and Noorduyn, S. and Rodrigues, M. and Lawson, D.O. and Thabane, L. and Montori, V.
DOI: 10.1111/jebm.12487Cochrane Database of Systematic Reviews
Jasani, B. and Mitra, S. and Shah, P.S.
DOI: 10.1002/14651858.CD010061.pub5Journal of Neonatal-Perinatal Medicine
Afifi, J. and Leijser, L.M. and De Vries, L.S. and Shah, P.S. and Mitra, S. and Brouwer, M.J. and Walling, S. and McNeely, P.D.
DOI: 10.3233/NPM-221071Acta Paediatrica, International Journal of Paediatrics
Bamat, N.A. and Jensen, E.A. and Mitra, S.
DOI: 10.1111/apa.16228Journal of Perinatology
Jain, A. and Giesinger, R.E. and Dakshinamurti, S. and ElSayed, Y. and Jankov, R.P. and Weisz, D.E. and Lakshminrusimha, S. and Mitra, S. and Mazwi, M.L. and Ting, J. and Narvey, M. and McNamara, P.J.
DOI: 10.1038/s41372-021-01296-zCochrane Database of Systematic Reviews
Mitra, S. and Gardner, C.E. and MacLellan, A. and Disher, T. and Styranko, D.M. and Kuhle, S. and Johnston, B.C. and Dorling, J.
DOI: 10.1002/14651858.CD013846Current Opinion in Pediatrics
Mitra, S. and McMillan, D.
DOI: 10.1097/MOP.0000000000000993Hypoxic Respiratory Failure in the Newborn: From Origins to Clinical Management
Mitra, S. and Keller, R.L. and Shah, P.S.
DOI: 10.1201/9780367494018-29Journal of Perinatology
Hillier, K. and Jones, K. and MacInnis, M. and Mitra, S.
DOI: 10.1038/s41372-021-01046-1BMJ Open
Mitra, S. and Jain, A. and Ting, J.Y. and Ben Fadel, N. and Drolet, C. and Abou Mehrem, A. and Soraisham, A. and Jasani, B. and Louis, D. and Lapointe, A. and Dorling, J. and Khurshid, F. and Hyderi, A. and Kumaran, K. and Bodani, J. and Weisz, D. and Alvaro, R. and Adie, M. and Stavel, M. and Morin, A. and Bhattacharya, S. and Kanungo, J. and Canning, R. and Ye, X.Y. and Hatfield, T. and Gardner, C.E. and Shah, P.
DOI: 10.1136/bmjopen-2021-050682Seminars in Fetal and Neonatal Medicine
Mitra, S. and Dorling, J. and Johnston, B.C.
DOI: 10.1016/j.siny.2021.101194PLoS ONE
Keir, A. and Bamat, N. and Hennebry, B. and King, B. and Patel, R. and Wright, C. and Scrivens, A. and ElKhateeb, O. and Mitra, S. and Roland, D.
DOI: 10.1371/journal.pone.0252472Clinics in Perinatology
Mitra, S. and McNamara, P.J.
DOI: 10.1016/j.clp.2020.05.007Neonatology
Mitra, S. and Babadagli, M.E. and Hatfield, T. and Depalma, A. and McCord, H. and El-Naggar, W. and Schm{\"o}lzer, G.M. and McMillan, D.D.
DOI: 10.1159/000508555Cochrane Database of Systematic Reviews
Kuhle, S. and Hoffmann, D.U. and Mitra, S. and Urschitz, M.S.
DOI: 10.1002/14651858.CD007074.pub3Journal of Perinatology
El-Naggar, W. and Yoon, E.W. and McMillan, D. and Afifi, J. and Mitra, S. and Singh, B. and da Silva, O. and Lee, S.K. and Shah, P.S.
DOI: 10.1038/s41372-020-0678-1Acta Paediatrica, International Journal of Paediatrics
Mitra, S. and Reid, M. and McDougall, B. and Johnston, B.C.
DOI: 10.1111/apa.14879Archives of Disease in Childhood
Paes, B. and Mitra, S.
DOI: 10.1136/archdischild-2018-316408Pediatric Pulmonology
Mukerji, A. and Wahab, M.G.A. and Mitra, S. and Mondal, T. and Paterson, D. and Beck, J. and Fusch, C.
DOI: 10.1002/ppul.24312Journal of Perinatology
Singh, B. and Shah, P.S. and Afifi, J. and Simpson, C.D. and Mitra, S. and Dow, K. and El-Naggar, W.
DOI: 10.1038/s41372-019-0315-zBMJ Open
Mitra, S. and Disher, T. and Pichler, G. and D{'}Souza, B. and McCord, H. and Chayapathi, V. and Jones, K. and Schm{\"o}lzer, G.
DOI: 10.1136/bmjopen-2018-028066Trials
Pichler, G. and Baumgartner, S. and Biermayr, M. and Dempsey, E. and Fuchs, H. and Goos, T.G. and Lista, G. and Lorenz, L. and Karpinski, L. and Mitra, S. and Kornhauser-Cerar, L. and Avian, A. and Urlesberger, B. and Schm{\"o}lzer, G.M.
DOI: 10.1186/s13063-019-3258-yJAMA - Journal of the American Medical Association
Mitra, S. and Florez, I.D. and Tamayo, M.E. and Mbuagbaw, L. and Vanniyasingam, T. and Veroniki, A.A. and Zea, A.M. and Zhang, Y. and Sadeghirad, B. and Thabane, L.
DOI: 10.1001/jama.2018.1896Journal of Perinatology
Mitra, S. and Singh, B. and El-Naggar, W. and McMillan, D.D.
DOI: 10.1038/s41372-017-0037-zCochrane Database of Systematic Reviews
Evans, P. and O'reilly, D. and Flyer, J.N. and Mitra, S. and Soll, R.
DOI: 10.1002/14651858.CD013133Pediatrics
Disher, T. and Cameron, C. and Mitra, S. and Cathcart, K. and Campbell-Yeo, M.
DOI: 10.1542/peds.2018-0401Journal of Pediatrics
Mitra, S. and El Azrak, M. and McCord, H. and Paes, B.A.
DOI: 10.1016/j.jpeds.2018.08.006Journal of Parenteral and Enteral Nutrition
Fusch, G. and Mitra, S. and Topp, H. and Agarwal, A. and Yiu, S.H. and Bruhs, J. and Rochow, N. and Lange, A. and Heckmann, M. and Fusch, C.
DOI: 10.1002/jpen.1156Journal of Maternal-Fetal and Neonatal Medicine
Mitra, S. and Chan, A.K. and Paes, B.A.
DOI: 10.3109/14767058.2016.1163684BMJ Open
Mitra, S. and Florez, I.D. and Tamayo, M.E. and Aune, D. and Mbuagbaw, L. and Veroniki, A.-A. and Thabane, L.
DOI: 10.1136/bmjopen-2016-011271Acta Paediatrica, International Journal of Paediatrics
Fusch, G. and Mitra, S. and Rochow, N. and Fusch, C.
DOI: 10.1111/apa.12804Neonatology
Mitra, S. and Aune, D. and Speer, C.P. and Saugstad, O.D.
DOI: 10.1159/000357556Annals of Pediatric Cardiology
Mitra, S. and Saha, A.K. and Sardar, S.K. and Singh, A.K.
DOI: 10.4103/0974-2069.115278Congenital Heart Disease
Mitra, S. and R?nnestad, A. and Holmstr?m, H.
DOI: 10.1111/chd.12143Iranian Journal of Pediatrics
Mukherjee, S. and Roy, P. and Mitra, S. and Samanta, M. and Chatterjee, S.
Journal of Tropical Pediatrics
Mitra, S. and Samanta, M. and Sarkar, M. and Roy, P. and Chatterjee, S.
DOI: 10.1093/tropej/fmr092Journal of Pediatric Infectious Diseases
Mukherjee, S. and Mitra, S. and Samanta, M. and Roy, P. and Sarkar, M. and Chatterjee, S.
DOI: 10.3233/JPI-2012-0339Journal of Tropical Pediatrics
Das, S. and Ghosh, M. and Mitra, S. and Chatterjee, R. and Bhattacharyya, S. and De, A.K. and Chakraborty, S.
DOI: 10.1093/tropej/fmr080Journal of Tropical Pediatrics
Mitra, S. and Samanta, M. and Sarkar, M. and De, A.K. and Chatterjee, S.
DOI: 10.1093/tropej/fmq083Indian Pediatrics
Mitra, S. and Samanta, M. and Sarkar, M. and Chatterjee, S.
DOI: 10.1007/s13312-011-0092-zIndian Journal of Pathology and Microbiology
Mitra, S. and Samanta, M. and Sarkar, M. and Chatterjee, S.
DOI: 10.4103/0377-4929.72098Patent ductus arteriosus (PDA) is one of the common most cardiovascular problems in babies born extremely premature. Controversy exists on when to treat a PDA, if at all, and what is the safest and most effective medication to treat a PDA in extremely preterm infants. My current research program explores different aspects of this problem through the following projects:
1. Selective Early Medical Treatment of the Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot Randomized Controlled Trial (the SMART PDA Trial)
This is a multicenter, multinational randomized controlled trial that exclusively enrolls babies born below 26 weeks of gestational age with the overarching goal to explore if selective early medical therapy of a moderate-severe PDA shunt identified based on pre-defined clinical signs & routine screening echocardiography improves clinically meaningful outcomes. This study is funded by the CIHR Early Career Investigators in Maternal, Reproductive, Child and Youth Health Grant 2020.
2. Relative effectiveness and safety of pharmacotherapeutic agents for treatment patent ductus arteriosus(PDA) in preterm infants: A National Comparative Effectiveness Research (CER) Project
This is a multicenter prospective observational study conducted through the Canadian Neonatal Network across 20 Canadian neonatal intensive care units that explores which of the commonly used prostaglandin-inhibitor regimens is the safest and most effective in treating a PDA in extremely preterm infants. This study is funded by the CIHR Fall 2019 Project Grant.
3. Evidence synthesis on PDA management in preterm infants – Cochrane Database of Systematic Reviews
With over 80 randomized controlled trials on this topic, rigorous synthesis of the existing evidence is essential for developing trustworthy clinical practice guidelines. My research team including students, colleagues and collaborators are currently involved in or have recently contributed to several Cochrane systematic reviews on PDA management:
a. Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants
b. Feeding during treatment of patent ductus arteriosus
c. Fluid restriction for treatment of symptomatic patent ductus arteriosus in preterm infants
d. Indomethacin for symptomatic patent ductus arteriosus in preterm infants
e. Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews
f. Invasive management for patent ductus arteriosus in preterm infants
g. Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants
h. Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network meta-analysis
2021/4 – 2024/3: Project title: Selective Early Medical Treatment of the Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot Randomized Controlled Trial (the SMART PDA Trial). Funding Source: Canadian Institutes of Health Research (CIHR) Early Career Investigators in Maternal, Reproductive, Child and Youth Health Grant 2020 (Principal Investigator). Total Funding – $208,998 (Canadian dollar) [including 1:1 matching fund support from the Dalhousie Medical Research Foundation; IWK Health Research; Department of Pediatrics, Dalhousie University]
2020/1 – 2024/1: Project title: Relative effectiveness and safety of pharmacotherapeutic agents for treatment patent ductus arteriosus (PDA) in preterm infants: A National Comparative Effectiveness Research (CER) Project. Funding Source: Canadian Institutes of Health Research (CIHR) Project Grant Fall 2019 (Principal Investigator). Total Funding – $313,652 (Canadian dollar)
2022/9 – 2025/8. Project title: Increasing capacity for Maternal and PAediatric Clinical Trials (IMPACT) in Canada. Principal Applicant: Dr. Lauren Kelly, Associate Professor, Depts. of Pharmacology and Therapeutics, and Community Health Sciences, University of Manitoba. Funding Source: CIHR Training Grant: Clinical Trials Training Platforms (Co-Investigator). Total Funding – $ 4,907,350 (Canadian dollar)
2022/9 – 2025/8. Project title: Increasing capacity for Maternal and PAediatric Clinical Trials (IMPACT) in Canada. Principal Applicant: Dr. Jean Bourbeau, Research Institute at McGill University Health Centre. Funding Source: CIHR Training Grant: Clinical Trials Training Platforms (Co-Investigator). Total Funding – $ 11.3M (Canadian dollar)
2022/4 – 2027/3. Project title: Dopamine vs. Norepinephrine for hypotension in very preterm infants with late-onset sepsis: A National Comparative Effectiveness Research (CER) Project. Principal Applicant: Dr. Amish Jain, Associate Professor, University of Toronto. Funding Source: Canadian Institutes of Health Research (CIHR) Project Grant Fall 2021 (Co-Investigator). Total Funding – $ 473,761 (Canadian dollar)
2021/6 – 2022/5. Project title: Parental presence restrictions due to COVID-19: Examining impact and priorities for neonatal care (The PRESENCE Study). Principal Applicant: Dr. Marsha Campbell-Yeo, Professor, Dalhousie University. Funding Source: Canadian Institutes of Health Research (CIHR) Emerging COVID-19 Research Gaps and Priorities Funding Opportunity (Co-Investigator). Total Funding – $193,100 (Canadian dollar)
2021/1 – 2025/1: Project title: REdefining the SignificancE and Treatment threshold for Patent Ductus Arteriosus in preterm infants (RESET-PDA). Principal Applicant: Dr. Dany Weisz, Assistant Professor, University of Toronto. Funding Source: Canadian Institutes of Health Research (CIHR) Project Grant Fall 2020 (Co-Investigator). Total Funding – $566,100 (Canadian dollar)
2022/11 – Recipient of the Emerging Professional Award at the 2022 Discovery Awards for Science and Innovation: Discovery Centre, Nova Scotia
2022/5 – Invited panelist on "Game Changers in Health Research and Health Innovation" event: Parliamentary Health Research Caucus, Research Canada
2020/12 – Department of Pediatrics Research Award for Research Excellence [Category: In the first 10 years of an academic appointment], Department of Pediatrics, Dalhousie University
2020/12 – 2021 CNPRM (Canadian National Perinatal Research Meeting) Early Career Researcher Invited Lectureship
2019/6 – Rising Star Award: Canadian Child Health Clinician Scientist Program (CCHCSP), Toronto, ON
2019/5 – Richard Merritt Special Appreciation Award: Canadian Society of Hospital Pharmacists, Ottawa, ON
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BC Children’s Hospital Research Institute (BCCHR) is pleased to congratulate the recipients of the 2025 Outstanding Achievement Awards. This program, generously funded by the BC Children’s Hospital Foundation, plays a pivotal role in acknowledging and nurturing excellence within our research community.
Congratulations to BC Children’s Hospital Research Institute (BCCHR) and Women’s Health Research Institute (WHRI) investigators and their teams who were awarded funding through the Canadian Institutes of Health Research (CIHR) Spring 2025 Project Grant competition.
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