Overview

The focus of the neonatal neurology research group is to better understand brain development and injury in the newborn. Using advanced magnetic resonance (MR) techniques and bedside brain monitoring we study how white matter injury and systemic illness affects brain development in critically ill newborns. A better understanding of the factors that impact brain development and injury will allow us to directly improve the neurodevelopmental outcome of high-risk newborns.

Neurodevelopmental impairments are common in newborns delivered prior to term age and in newborns with heart birth defects, and result in a large burden of long-term disability. White matter injury, abnormal brain development and systemic illness are interrelated abnormalities that commonly follow preterm birth or heart birth defects, with focal non-cystic white matter injury being the characteristic pattern of brain injury. Though focal non-cystic white matter injury is associated with diffuse abnormalities of motor and cognitive function, how this happens is unknown. Systemic illness (e.g. infection) and therapy (e.g. steroids) may also be associated with diffuse abnormalities of motor and cognitive function.

Publications

Pain in the newborn brain: a neural signature
The Lancet Digital Health
Emma G Duerden and Steven P Miller
DOI: 10.1016/s2589-7500(20)30191-6
09/2020

The Effect of Music and White Noise on Electroencephalographic (EEG) Functional Connectivity in Neonates in the Neonatal Intensive Care Unit.
Journal of child neurology
Akiyama A and Tsai JD and W Y Tam E and Kamino D and Hahn C and Go CY and Chau V and Whyte H and Wilson D and McNair C and Papaioannou V and Hugh SC and Papsin BC and Nishijima S and Ochi A
DOI: 10.1177/0883073820947894
PubMed: 32838628
08/2020

Decreased Brain Volumes and Infants With Congenital Heart Disease Undergoing Venoarterial Extracorporeal Membrane Oxygenation.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Chao BK and Claessens NHP and Lim JM and Gorodetsky C and Au-Young SH and Guerguerian AM and Marini D and Blaser S and Shroff M and Saini AK and Seed M and Chau V and Miller SP
DOI: 10.1097/pcc.0000000000002336
PubMed: 32195905
08/2020

Knowledge Empowers: Responding to the Knowledge Needs of Youth with Disabilities and Families during the Pandemic.
Physical & occupational therapy in pediatrics
Majnemer A and Leblanc A and Faust L and Costello C and Thomson D and Goldowitz D and Miller SP
DOI: 10.1080/01942638.2020.1801298
PubMed: 32748661
08/2020

Mechanical Ventilation Duration, Brainstem Development, and Neurodevelopment in Children Born Preterm: A Prospective Cohort Study.
The Journal of pediatrics
Guillot M and Guo T and Ufkes S and Schneider J and Synnes A and Chau V and Grunau RE and Miller SP
DOI: 10.1016/j.jpeds.2020.05.039
PubMed: 32454115
05/2020

Long-term postnatal outcomes of fetuses with prenatally suspected septo-optic dysplasia.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
Shinar S and Blaser S and Chitayat D and Selvanathan T and Chau V and Shannon P and Agrawal S and Ryan G and Pruthi V and Miller SP and Krishnan P and Van Mieghem T
DOI: 10.1002/uog.22018
PubMed: 32196785
03/2020

Longitudinal neurodevelopmental outcomes in preterm twins.
Pediatric research
Christensen R and Chau V and Synnes A and Grunau RE and Miller SP
DOI: 10.1038/s41390-020-0840-7
PubMed: 32172281
03/2020

The influence of pain, agitation, and their management on the immature brain.
Pediatric research
McPherson C and Miller SP and El-Dib M and Massaro AN and Inder TE
DOI: 10.1038/s41390-019-0744-6
PubMed: 31896130
01/2020

Pain in the newborn brain: a neural signature
The Lancet Digital Health
Duerden, E.G. and Miller, S.P.
DOI: 10.1016/S2589-7500(20)30191-6
2020

Decreased Brain Volumes and Infants With Congenital Heart Disease Undergoing Venoarterial Extracorporeal Membrane Oxygenation
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Chao, B.K. and Claessens, N.H.P. and Lim, J.M. and Gorodetsky, C. and Au-Young, S.H. and Guerguerian, A.-M. and Marini, D. and Blaser, S. and Shroff, M. and Saini, A.K. and Seed, M. and Chau, V. and Miller, S.P.
DOI: 10.1097/PCC.0000000000002336
2020

Socioeconomic status and brain injury in children born preterm: modifying neurodevelopmental outcome
Pediatric Research
Benavente-Fern{\'a}ndez, I. and Siddiqi, A. and Miller, S.P.
DOI: 10.1038/s41390-019-0646-7
2020

Pearls & Oy-sters: Fatal brain edema is a rare complication of severe CACNA1A-related disorder
Neurology
Gauquelin, L. and Hawkins, C. and Tam, E.W.Y. and Miller, S.P. and Yoon, G.
DOI: 10.1212/WNL.0000000000009223
2020

Brain Injury in Infants with Critical Congenital Heart Disease: Insights from Two Clinical Cohorts with Different Practice Approaches.
The Journal of pediatrics
Claessens NHP and Chau V and de Vries LS and Jansen NJG and Au-Young SH and Stegeman R and Blaser S and Shroff M and Haas F and Marini D and Breur JMPJ and Seed M and Benders MJNL and Miller SP
DOI: 10.1016/j.jpeds.2019.07.017
PubMed: 31451185
08/2019

The Influence of Early Nutrition on Brain Growth and Neurodevelopment in Extremely Preterm Babies: A Narrative Review.
Nutrients
Cormack BE and Harding JE and Miller SP and Bloomfield FH
DOI: 10.3390/nu11092029
PubMed: 31480225
08/2019

Predicting developmental outcomes in preterm infants: A simple white matter injury imaging rule.
Neurology
Cayam-Rand D and Guo T and Grunau RE and Benavente-Fernández I and Synnes A and Chau V and Branson H and Latal B and McQuillen P and Miller SP
DOI: 10.1212/wnl.0000000000008172
PubMed: 31467250
08/2019

From Diagnoses to Ongoing Journey: Parent Experiences Following Congenital Heart Disease Diagnoses.
Journal of pediatric psychology
Williams TS and McDonald KP and Roberts SD and Chau V and Seed M and Miller SP and Sananes R
DOI: 10.1093/jpepsy/jsz055
PubMed: 31290975
07/2019

Improving paediatric medications: A prescription for Canadian children and youth.
Paediatrics & child health
Hepburn CM and Gilpin A and Autmizguine J and Denburg A and Dupuis LL and Finkelstein Y and Gruenwoldt E and Ito S and Jong G' and Lacaze-Masmonteil T and Levy D and Macleod S and Litalien C
DOI: 10.1093/pch/pxz079
PubMed: 31379437
07/2019

Neurologic Examination Findings Associated With Small Cerebellar Volumes After Prematurity.
Journal of child neurology
Tam EWY and Chau V and Lavoie R and Chakravarty MM and Guo T and Synnes A and Zwicker J and Grunau R and Miller SP
DOI: 10.1177/0883073819847925
PubMed: 31111765
05/2019

Hub distribution of the brain functional networks of newborns prenatally exposed to maternal depression and SSRI antidepressants.
Depression and anxiety
Rotem-Kohavi N and Williams LJ and Muller AM and Abdi H and Virji-Babul N and Bjornson BH and Brain U and Werker JF and Grunau RE and Miller SP and Oberlander TF
DOI: 10.1002/da.22906
PubMed: 31066992
05/2019

Association of Socioeconomic Status and Brain Injury With Neurodevelopmental Outcomes of Very Preterm Children.
JAMA network open
Benavente-Fernández I and Synnes A and Grunau RE and Chau V and Ramraj C and Glass T and Cayam-Rand D and Siddiqi A and Miller SP
DOI: 10.1001/jamanetworkopen.2019.2914
PubMed: 31050776
05/2019

Hippocampus, Amygdala, and Thalamus Volumes in Very Preterm Children at 8 Years: Neonatal Pain and Genetic Variation.
Frontiers in Behavioral Neuroscience
Chau CMY and Ranger M and Bichin M and Park MTM and Amaral RSC and Chakravarty M and Poskitt K and Synnes AR and Miller SP and Grunau RE
DOI: 10.3389/fnbeh.2019.00051
PubMed: 30941021
03/2019

Anticoagulation therapy and the risk of perioperative brain injury in neonates with congenital heart disease.
The Journal of thoracic and cardiovascular surgery
Leijser LM and Chau V and Seed M and Poskitt KJ and Synnes A and Blaser S and Au-Young SH and Hickey EJ and Campbell A and McQuillen PS and Miller SP
DOI: 10.1016/j.jtcvs.2019.02.029
PubMed: 30981520
02/2019

Trends in investigations of abuse or neglect referred by hospital personnel in Ontario.
BMJ paediatrics open
Fallon B and Filippelli J and Joh-Carnella N and Miller SP and Denburg A
DOI: 10.1136/bmjpo-2018-000386
PubMed: 30957025
02/2019

Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18¿months.
EBioMedicine
Chau CMY and Ross CJD and Chau V and Synnes AR and Miller SP and Carleton B and Grunau RE
DOI: 10.1016/j.ebiom.2019.01.042
PubMed: 30709768
01/2019

Preterm brain Injury: White matter injury.
Handbook of clinical neurology
Schneider J and Miller SP
DOI: 10.1016/b978-0-444-64029-1.00007-2
PubMed: 31324309
01/2019

Pattern of Brain Injury Predicts Long-Term Epilepsy Following Neonatal Encephalopathy.
Journal of child neurology
Xu Q and Chau V and Sanguansermsri C and Muir KE and Tam EWY and Miller SP and Wong DST and Chen H and Wong PKH and Zwicker JG and Poskitt KJ and Hill A and Roland EH
DOI: 10.1177/0883073818822361
PubMed: 30642234
01/2019

White matter injury in term neonates with congenital heart diseases: Topology & comparison with preterm newborns
NeuroImage
Guo, T. and Chau, V. and Peyvandi, S. and Latal, B. and McQuillen, P.S. and Knirsch, W. and Synnes, A. and Feldmann, M. and Naef, N. and Chakravarty, M.M. and De Petrillo, A. and Duerden, E.G. and Barkovich, A.J. and Miller, S.P.
DOI: 10.1016/j.neuroimage.2018.06.004
2019

Improving paediatric medications: A prescription for Canadian children and youth,L'amélioration des médicaments à usage pédiatrique: une prescription pour les enfants et les adolescents canadiens
Paediatrics and Child Health (Canada)
Hepburn, C.M. and Gilpin, A. and Autmizguine, J. and Denburg, A. and Dupuis, L.L. and Finkelstein, Y. and Gruenwoldt, E. and Ito, S. and Jong, G. and Lacaze-Masmonteil, T. and Levy, D. and Macleod, S. and Miller, S.P. and Offringa, M. and Pinsk, M. and Power, B. and Rieder, M. and Litalien, C.
DOI: 10.1093/pch/pxz094
2019

White matter injury predicts disrupted functional connectivity and microstructure in very preterm born neonates
NeuroImage: Clinical
Duerden, E.G. and Halani, S. and Ng, K. and Guo, T. and Foong, J. and Glass, T.J.A. and Chau, V. and Branson, H.M. and Sled, J.G. and Whyte, H.E. and Kelly, E.N. and Miller, S.P.
DOI: 10.1016/j.nicl.2018.11.006
2019

Predictive connectome subnetwork extraction with anatomical and connectivity priors
Computerized Medical Imaging and Graphics
Brown, C.J. and Miller, S.P. and Booth, B.G. and Zwicker, J.G. and Grunau, R.E. and Synnes, A.R. and Chau, V. and Hamarneh, G.
DOI: 10.1016/j.compmedimag.2018.08.009
2019

The neonatal brain in critical congenital heart disease: Insights and future directions
NeuroImage
Peyvandi, S. and Latal, B. and Miller, S.P. and McQuillen, P.S.
DOI: 10.1016/j.neuroimage.2018.05.045
2019

A fast segmentation-free fully automated approach to white matter injury detection in preterm infants
Medical and Biological Engineering and Computing
Mukherjee, S. and Cheng, I. and Miller, S. and Guo, T. and Chau, V. and Basu, A.
DOI: 10.1007/s11517-018-1829-9
2019

Plasma cholesterol levels and brain development in preterm newborns
Pediatric Research
Kamino, D. and Chau, V. and Studholme, C. and Liu, M. and Xu, D. and Barkovich, A.J. and Ferriero, D.M. and Miller, S.P. and Brant, R. and Tam, E.W.Y.
DOI: 10.1038/s41390-018-0260-0
2019

Predicting developmental outcomes in preterm infants: A simple white matter injury imaging rule
Neurology
Cayam-Rand, D. and Guo, T. and Grunau, R.E. and Benavente-Fern{\'a}ndez, I. and Synnes, A. and Chau, V. and Branson, H. and Latal, B. and Mcquillen, P. and Miller, S.P.
DOI: 10.1212/WNL.0000000000008172
2019

Concurrent Validity of the Bayley-III and the Peabody Developmental Motor Scales-2 at 18 Months
Physical and Occupational Therapy in Pediatrics
Gill, K. and Osiovich, A. and Synnes, A. and A. Agnew, J. and Grunau, R.E. and Miller, S.P. and Zwicker, J.G.
DOI: 10.1080/01942638.2018.1546255
2019

Commentary on “The long-term effect of perinatal asphyxia on hippocampal volumes”
Pediatric Research
Cayam-Rand, D. and Miller, S.P.
DOI: 10.1038/s41390-018-0209-3
2019

Alterations in Resting-State Networks Following In Utero Selective Serotonin Reuptake Inhibitor Exposure in the Neonatal Brain
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Rotem-Kohavi, N. and Williams, L.J. and Virji-Babul, N. and Bjornson, B.H. and Brain, U. and Werker, J.F. and Grunau, R.E. and Miller, S.P. and Oberlander, T.F.
DOI: 10.1016/j.bpsc.2018.08.004
2019

Impact of Perioperative Brain Injury and Development on Feeding Modality in Infants With Single Ventricle Heart Disease
Journal of the American Heart Association
Hsieh, A. and Tabbutt, S. and Xu, D. and Barkovich, A.J. and Miller, S. and McQuillen, P. and Peyvandi, S.
DOI: 10.1161/JAHA.119.012291
2019

Preterm brain Injury: White matter injury
Handbook of Clinical Neurology
Schneider, J. and Miller, S.P.
DOI: 10.1016/B978-0-444-64029-1.00007-2
2019

Associations between Age at Arterial Switch Operation, Brain Growth, and Development in Infants with Transposition of the Great Arteries
Circulation
Lim, J.M. and Porayette, P. and Marini, D. and Chau, V. and Au-Young, S.H. and Saini, A. and Ly, L.G. and Blaser, S. and Shroff, M. and Branson, H.M. and Sananes, R. and Hickey, E.J. and Gaynor, J.W. and Van Arsdell, G. and Miller, S.P. and Seed, M.
DOI: 10.1161/CIRCULATIONAHA.118.037495
2019

Imaging the term neonatal brain.
Paediatrics & child health
Sorokan ST and Jefferies AL and Miller SP
DOI: 10.1093/pch/pxx161
PubMed: 30657135
07/2018

Brain abnormalities in children and adolescents with chronic kidney disease.
Pediatric research
DOI: 10.1038/s41390-018-0037-5
PubMed: 29967532
07/2018

In their own words: developing the Parent Experiences Questionnaire following neonatal brain injury using participatory design.
Brain injury
Williams TS and McDonald KP and Roberts SD and Westmacott R and Ahola Kohut S and Dlamini N and Miller SP
DOI: 10.1080/02699052.2018.1495844
PubMed: 30015511
07/2018

Imaging Evidence of the Effect of Socio-Economic Status on Brain Structure and Development.
Seminars in pediatric neurology
Leijser LM and Siddiqi A and Miller SP
DOI: 10.1016/j.spen.2018.03.004
PubMed: 30293587
06/2018

Association of Histologic Chorioamnionitis With Perinatal Brain Injury and Early Childhood Neurodevelopmental Outcomes Among Preterm Neonates.
JAMA pediatrics
DOI: 10.1001/jamapediatrics.2018.0102
PubMed: 29610829
06/2018

Neonatal Brain Injury and Timing of Neurodevelopmental Assessment in Patients With Congenital Heart Disease.
Journal of the American College of Cardiology
DOI: 10.1016/j.jacc.2018.02.068
PubMed: 29724352
05/2018

Do cash transfer programmes yield better health in the first year of life? A systematic review linking low-income/middle-income and high-income contexts.
Archives of disease in childhood
Siddiqi A and Rajaram A and Miller SP
DOI: 10.1136/archdischild-2017-314301
PubMed: 29705725
04/2018

Procedural pain and oral glucose in preterm neonates: brain development and sex-specific effects.
Pain
DOI: 10.1097/j.pain.0000000000001123
PubMed: 29200180
03/2018

Cardiovascular Associations with Abnormal Brain Magnetic Resonance Imaging in Neonates with Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia and Rewarming.
American journal of perinatology
More KS and Sakhuja P and Giesinger RE and Ting JY and Keyzers M and Sheth JN and Lapointe A and Jain A and Moore AM and Miller SP and McNamara PJ
DOI: 10.1055/s-0038-1629900
PubMed: 29475200
02/2018

Multiple Postnatal Infections in Newborns Born Preterm Predict Delayed Maturation of Motor Pathways at Term-Equivalent Age with Poorer Motor Outcomes at 3 Years.
The Journal of pediatrics
DOI: 10.1016/j.jpeds.2017.12.041
PubMed: 29398063
02/2018

Nutrient Intake in the First Two Weeks of Life and Brain Growth in Preterm Neonates.
Pediatrics
DOI: 10.1542/peds.2017-2169
PubMed: 29440285
02/2018

Imaging the neonatal brain in the 21st century: why, when and how?
Archives of disease in childhood. Fetal and neonatal edition
Cheong JLY and Miller SP
DOI: 10.1136/archdischild-2017-313572
PubMed: 29074721
01/2018

Posthemorrhagic ventricular dilatation in preterm infants: When best to intervene?
Neurology
DOI: 10.1212/WNL.0000000000004984
PubMed: 29367448
01/2018

The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease.
The Journal of thoracic and cardiovascular surgery
Peyvandi S and Kim H and Lau J and Barkovich AJ and Campbell A and Miller S and Xu D and McQuillen P
DOI: 10.1016/j.jtcvs.2017.08.019
PubMed: 28918207
01/2018

Brain Injury in the Preterm Infant
Avery's Diseases of the Newborn: Tenth Edition
Back, S.A. and Miller, S.P.
DOI: 10.1016/B978-0-323-40139-5.00060-7
2018

Early procedural pain is associated with regionally-specific alterations in thalamic development in preterm neonates
Journal of Neuroscience
Duerden, E.G. and Grunau, R.E. and Guo, T. and Foong, J. and Pearson, A. and Au-Young, S. and Lavoie, R. and Chakravarty, M.M. and Chau, V. and Synnes, A. and Miller, S.P.
DOI: 10.1523/JNEUROSCI.0867-17.2017
2018

Association of Histologic Chorioamnionitis with Perinatal Brain Injury and Early Childhood Neurodevelopmental Outcomes among Preterm Neonates
Obstetrical and Gynecological Survey
Bierstone, D. and Wagenaar, N. and Gano, D.L. and Guo, T. and Georgio, G. and Groenendaal, F. and De Vries, L.S. and Varghese, J. and Glass, H.C. and Chung, C. and Terry, J. and Rijpert, M. and Grunau, R.E. and Synnes, A. and Barkovich, A.J. and Ferriero, D.M. and Benders, M. and Chau, V. and Miller, S.P.
DOI: 10.1097/01.ogx.0000549830.07599.6f
2018

Neonatal stroke and haematuria: Questions
Pediatric Nephrology
Kellett, S. and Lemaire, M. and Miller, S.P. and Licht, C. and Yoon, G. and Dlamini, N. and Noone, D.
DOI: 10.1007/s00467-017-3745-x
2018

COL4A1 and fetal vascular origins of schizencephaly
Neurology
Khalid, R. and Krishnan, P. and Andres, K. and Blaser, S. and Miller, S. and Moharir, M. and Dlamini, N.
DOI: 10.1212/WNL.0000000000004890
2018

Neonatal stroke and haematuria: Answers
Pediatric Nephrology
Kellett, S. and Lemaire, M. and Miller, S.P. and Licht, C. and Yoon, G. and Dlamini, N. and Noone, D.
DOI: 10.1007/s00467-017-3747-8
2018

The placenta and neurodevelopment in preterm newborns
NeoReviews
Garfinkle, J. and Miller, S.P.
DOI: 10.1542/neo.19-8-e456
2018

Postnatal polyunsaturated fatty acids associated with larger preterm brain tissue volumes and better outcomes
Pediatric Research
Kamino, D. and Studholme, C. and Liu, M. and Chau, V. and Miller, S.P. and Synnes, A. and Rogers, E.E. and Barkovich, A.J. and Ferriero, D.M. and Brant, R. and Tam, E.W.Y.
DOI: 10.1038/pr.2017.230
2018

Imaging the term neonatal brain,L'imagerie du cerveau du nouveau-né à terme
Paediatrics and Child Health (Canada)
Sorokan, S.T. and Jefferies, A.L. and Miller, S.P.
DOI: 10.1093/pch/pxy002
2018

Early procedural pain is associated with regionally-specific alterations in thalamic development in preterm neonates.
The Journal of Neuroscience
Duerden EG and Grunau RE and Guo T and Foong J and Pearson A and Au-Young S and Lavoie R and Chakravarty MM and Chau V and Synnes A and Miller SP
DOI: 10.1523/jneurosci.0867-17.2017
PubMed: 29255007
12/2017

COL4A1 and fetal vascular origins of schizencephaly.
Neurology
Khalid R and Krishnan P and Andres K and Blaser S and Miller S and Moharir M and Dlamini N
DOI: 10.1212/wnl.0000000000004890
PubMed: 29282339
12/2017

Severe retinopathy of prematurity predicts delayed white matter maturation and poorer neurodevelopment.
Archives of disease in childhood. Fetal and neonatal edition
Glass TJA and Chau V and Gardiner J and Foong J and Vinall J and Zwicker JG and Grunau RE and Synnes A and Poskitt KJ and Miller SP
DOI: 10.1136/archdischild-2016-312533
PubMed: 28536205
11/2017

Small bite, big problem: Understanding severe microcephaly in Canada.
Paediatrics & Child Health
Nelson CRM and Demarsh A and Miller SP and Morris SK and Moore Hepburn C and Bitnun A and Moore A and Shevell M and Evans J and Tataryn J
DOI: 10.1093/pch/pxx153
PubMed: 29479266
11/2017

Complementary cortical gray and white matter developmental patterns in healthy, preterm neonates.
Human brain mapping
Rajagopalan V and Scott JA and Liu M and Poskitt K and Chau V and Miller S and Studholme C
DOI: 10.1002/hbm.23618
PubMed: 28608653
09/2017

GSK-3ß inhibitor TDZD-8 reduces neonatal hypoxic-ischemic brain injury in mice.
CNS neuroscience & therapeutics
Huang S and Wang H and Turlova E and Abussaud A and Ji X and Britto LR and Miller SP and Martinez A and Sun HS and Feng ZP
DOI: 10.1111/cns.12683
PubMed: 28256059
05/2017

Initiation of passive cooling at referring centre is most predictive of achieving early therapeutic hypothermia in asphyxiated newborns
Paediatrics & Child Health
Brigitte Lemyre and Linh Ly and Vann Chau and Anil Chacko and Nicholas Barrowman and Hilary Whyte and Steven P. Miller
DOI: 10.1093/pch/pxx062
05/2017

Harnessing Neuroimaging Capability in Pediatric Stroke: Proceedings of the Stroke Imaging Laboratory for Children Workshop.
Pediatric neurology
Dlamini N and Wintermark M and Fullerton H and Strother S and Lee W and Bjornson B and Guilliams KP and Miller S and Kirton A and Filippi CG and Linds A and Askalan R and deVeber G
DOI: 10.1016/j.pediatrneurol.2017.01.006
PubMed: 28259513
04/2017

Association between corpus callosum development on magnetic resonance imaging and diffusion tensor imaging, and neurodevelopmental outcome in neonates born very preterm.
Developmental medicine and child neurology
Malavolti AM and Chau V and Brown-Lum M and Poskitt KJ and Brant R and Synnes A and Grunau RE and Miller SP
DOI: 10.1111/dmcn.13364
PubMed: 27976377
04/2017

Clinical Risk Factors for Punctate White Matter Lesions on Early Magnetic Resonance Imaging in Preterm Newborns.
The Journal of pediatrics
Wagenaar N and Chau V and Groenendaal F and Kersbergen KJ and Poskitt KJ and Grunau RE and Synnes A and Duerden EG and de Vries LS and Miller SP and Benders MJNL
DOI: 10.1016/j.jpeds.2016.11.073
PubMed: 28063691
03/2017

Quantitative assessment of white matter injury in preterm neonates: Association with outcomes.
Neurology
Guo T and Duerden EG and Adams E and Chau V and Branson HM and Chakravarty MM and Poskitt KJ and Synnes A and Grunau RE and Miller SP
DOI: 10.1212/wnl.0000000000003606
PubMed: 28100727
02/2017

BrainNetCNN: Convolutional neural networks for brain networks; towards predicting neurodevelopment.
NeuroImage
Kawahara J and Brown CJ and Miller SP and Booth BG and Chau V and Grunau RE and Zwicker JG and Hamarneh G
DOI: 10.1016/j.neuroimage.2016.09.046
PubMed: 27693612
02/2017

The 'ouR-HOPE' approach for ethics and communication about neonatal neurological injury.
Developmental medicine and child neurology
Racine E and Bell E and Farlow B and Miller S and Payot A and Rasmussen LA and Shevell MI and Thomson D and Wintermark P
DOI: 10.1111/dmcn.13343
PubMed: 27915463
02/2017

Antenatal exposure to antidepressants is associated with altered brain development in very preterm-born neonates.
Neuroscience
Podrebarac SK and Duerden EG and Chau V and Grunau RE and Synnes A and Oberlander TF and Miller SP
DOI: 10.1016/j.neuroscience.2016.11.025
PubMed: 27890829
02/2017

Narcotics and Sedative Use in Preterm Neonates.
The Journal of pediatrics
Borenstein-Levin L and Synnes A and Grunau RE and Miller SP and Yoon EW and Shah PS and Canadian Neonatal Network Investigators
DOI: 10.1016/j.jpeds.2016.08.031
PubMed: 27614931
01/2017

Hypoxic-Ischemic Brain Injury in the Term Newborn
Swaiman's Pediatric Neurology
Vann Chau and Donna M. Ferriero and Steven P. Miller
DOI: 10.1016/b978-0-323-37101-8.00019-9
2017

Quantitative assessment of white matter injury in preterm neonates
Neurology
Guo, T. and Duerden, E.G. and Adams, E. and Chau, V. and Branson, H.M. and Chakravarty, M.M. and Poskitt, K.J. and Synnes, A. and Grunau, R.E. and Miller, S.P.
DOI: 10.1212/WNL.0000000000003606
2017

Combining spatial and non-spatial dictionary learning for automated labeling of intra-ventricular hemorrhage in neonatal brain MRI
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Liu, M. and Miller, S.P. and Chau, V. and Studholme, C.
DOI: 10.1007/978-3-319-66182-7_90
2017

Prediction of brain network age and factors of delayed maturation in very preterm infants
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Brown, C.J. and Moriarty, K.P. and Miller, S.P. and Booth, B.G. and Zwicker, J.G. and Grunau, R.E. and Synnes, A.R. and Chau, V. and Hamarneh, G.
DOI: 10.1007/978-3-319-66182-7_10
2017

Neurocognitive outcomes in term infants with neonatal encephalopathy
Fetal and Neonatal Brain Injury
Latal, B. and Liamlahi, R. and Miller, S.P.
DOI: 10.1017/9781316275498.048
2017

Hypoxic-Ischemic Brain Injury in the Term Newborn
Swaiman's Pediatric Neurology: Principles and Practice: Sixth Edition
Chau, V. and Ferriero, D.M. and Miller, S.P.
DOI: 10.1016/B978-0-323-37101-8.00019-9
2017

Pathophysiology of Neonatal White Matter Injury
Fetal and Neonatal Physiology
DOI: 10.1016/b978-0-323-35214-7.00169-4
2017

Increased subcortical oligodendroglia-like cells in pharmacoresistant focal epilepsy in children correlate with extensive epileptogenic zones.
Epilepsia
Sakuma S and Halliday WC and Nomura R and Baba S and Sato Y and Okanari K and Nakajima M and Widjaja E and Boelman C and Ochi A and Snead OC and Rutka JT and Drake J and Miller S and Otsubo H
DOI: 10.1111/epi.13590
PubMed: 27859041
12/2016

Fellowship Training in the Emerging Fields of Fetal-Neonatal Neurology and Neonatal Neurocritical Care.
Pediatric neurology
Smyser CD and Tam EWY and Chang T and Soul JS and Miller SP and Glass HC
DOI: 10.1016/j.pediatrneurol.2016.06.006
PubMed: 27473650
10/2016

Cerebral oxygen delivery is reduced in newborns with congenital heart disease.
The Journal of thoracic and cardiovascular surgery
Lim JM and Kingdom T and Saini B and Chau V and Post M and Blaser S and Macgowan C and Miller SP and Seed M
DOI: 10.1016/j.jtcvs.2016.05.027
PubMed: 27349283
10/2016

Interplay of brain structure and function in neonatal congenital heart disease.
Annals of clinical and translational neurology
Birca A and Vakorin VA and Porayette P and Madathil S and Chau V and Seed M and Doesburg SM and Blaser S and Nita DA and Sharma R and Duerden EG and Hickey EJ and Miller SP and Hahn CD
DOI: 10.1002/acn3.336
PubMed: 27648460
09/2016

Low plasma magnesium is associated with impaired brain metabolism in neonates with hypoxic-ischaemic encephalopathy.
Acta paediatrica (Oslo, Norway : 1992)
Chakkarapani E and Chau V and Poskitt KJ and Synnes A and Kwan E and Roland E and Miller SP
DOI: 10.1111/apa.13505
PubMed: 27336238
09/2016

Brain in Congenital Heart Disease Across the Lifespan: The Cumulative Burden of Injury.
Circulation
Marelli A and Miller SP and Marino BS and Jefferson AL and Newburger JW
DOI: 10.1161/circulationaha.115.019881
PubMed: 27185022
05/2016

Brain in Congenital Heart Disease Across the Lifespan: The Cumulative Burden of Injury.
Circulation
DOI: 10.1161/CIRCULATIONAHA.115.019881
PubMed: 27185022
05/2016

Smaller Cerebellar Growth and Poorer Neurodevelopmental Outcomes in Very Preterm Infants Exposed to Neonatal Morphine.
The Journal of pediatrics
Zwicker JG and Miller SP and Grunau RE and Chau V and Brant R and Studholme C and Liu M and Synnes A and Poskitt KJ and Stiver ML and Tam EW
DOI: 10.1016/j.jpeds.2015.12.024
PubMed: 26763312
05/2016

Early postnatal docosahexaenoic acid levels and improved preterm brain development.
Pediatric research
Tam EW and Chau V and Barkovich AJ and Ferriero DM and Miller SP and Rogers EE and Grunau RE and Synnes AR and Xu D and Foong J and Brant R and Innis SM
DOI: 10.1038/pr.2016.11
PubMed: 26761122
05/2016

Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury.
JAMA pediatrics
Peyvandi S and De Santiago V and Chakkarapani E and Chau V and Campbell A and Poskitt KJ and Xu D and Barkovich AJ and Miller S and McQuillen P
DOI: 10.1001/jamapediatrics.2015.4450
PubMed: 26902528
04/2016

Rodent Hypoxia-Ischemia Models for Cerebral Palsy Research: A Systematic Review.
Frontiers in neurology
DOI: 10.3389/fneur.2016.00057
PubMed: 27199883
04/2016

Reliability of Early Magnetic Resonance Imaging (MRI) and Necessity of Repeating MRI in Noncooled and Cooled Infants With Neonatal Encephalopathy.
Journal of child neurology
Chakkarapani E and Poskitt KJ and Miller SP and Zwicker JG and Xu Q and Wong DS and Roland EH and Hill A and Chau V
DOI: 10.1177/0883073815600865
PubMed: 26323498
04/2016

Midazolam dose correlates with abnormal hippocampal growth and neurodevelopmental outcome in preterm infants.
Annals of neurology
Duerden EG and Guo T and Dodbiba L and Chakravarty MM and Chau V and Poskitt KJ and Synnes A and Grunau RE and Miller SP
DOI: 10.1002/ana.24601
PubMed: 26754148
04/2016

MRI reveals hemodynamic changes with acute maternal hyperoxygenation in human fetuses with and without congenital heart disease.
Prenatal diagnosis
Porayette P and Madathil S and Sun L and Jaeggi E and Grosse-Wortmann L and Yoo SJ and Hickey E and Miller SP and Macgowan CK and Seed M
DOI: 10.1002/pd.4762
PubMed: 26701792
03/2016

The Fetal Heart Society: facilitating multidisciplinary collaborative fetal cardiovascular research.
Prenatal diagnosis
DOI: 10.1002/pd.4794
PubMed: 26918283
03/2016

Patch-based augmentation of Expectation-Maximization for brain MRI tissue segmentation at arbitrary age after premature birth.
NeuroImage
Liu M and Kitsch A and Miller S and Chau V and Poskitt K and Rousseau F and Shaw D and Studholme C
DOI: 10.1016/j.neuroimage.2015.12.009
PubMed: 26702777
02/2016

Response to Letter Regarding Article, "Reduced Fetal Cerebral Oxygen Consumption Is Associated With Smaller Brain Size in Fetuses With Congenital Heart Disease".
Circulation
Sun L and Macgowan CK and Sled JG and Yoo SJ and Manlhiot C and Porayette P and Grosse-Wortmann L and Jaeggi E and McCrindle B and Kingdom J and Hickey E and Miller S and Seed M
DOI: 10.1161/circulationaha.115.018748
PubMed: 26719396
01/2016

STEAM - Statistical Template Estimation for Abnormality Mapping: A personalized DTI analysis technique with applications to the screening of preterm infants.
NeuroImage
Booth BG and Miller SP and Brown CJ and Poskitt KJ and Chau V and Grunau RE and Synnes AR and Hamarneh G
DOI: 10.1016/j.neuroimage.2015.08.079
PubMed: 26515903
01/2016

Manual-Protocol Inspired Technique for Improving Automated MR Image Segmentation during Label Fusion.
Frontiers in neuroscience
Bhagwat N and Pipitone J and Winterburn JL and Guo T and Duerden EG and Voineskos AN and Lepage M and Miller SP and Pruessner JC and Chakravarty MM
DOI: 10.3389/fnins.2016.00325
PubMed: 27486386
2016

Response to letter regarding article, "Reduced fetal cerebral oxygen consumption is associated with smaller brain size in fetuses with congenital heart disease"
Circulation
Sun, L. and Macgowan, C.K. and Sled, J.G. and Yoo, S.-J. and Manlhiot, C. and Porayette, P. and Grosse-Wortmann, L. and Jaeggi, E. and McCrindle, B. and Kingdom, J. and Hickey, E. and Miller, S. and Seed, M.
DOI: 10.1161/CIRCULATIONAHA.115.018748
2016

Surface displacement based shape analysis of central brain structures in preterm-born children
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Garg, A. and Grunau, R.E. and Popuri, K. and Miller, S. and Bjornson, B. and Poskitt, K.J. and Beg, M.F.
DOI: 10.1117/12.2216914
2016

Sensory processing patterns in children born very preterm
American Journal of Occupational Therapy
Crozier, S.C. and Goodson, J.Z. and Mackay, M.L. and Synnes, A.R. and Grunau, R.E. and Miller, S.P. and Zwicker, J.G.
DOI: 10.5014/ajot.2016.018747
2016

Predictive subnetwork extraction with structural priors for infant connectomes
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Brown, C.J. and Miller, S.P. and Booth, B.G. and Zwicker, J.G. and Grunau, R.E. and Synnes, A.R. and Chau, V. and Hamarneh, G.
DOI: 10.1007/978-3-319-46720-7_21
2016

Multidisciplinary Collaboration in Fetal Cardiovascular Research: The Time Has Come
Journal of the American Society of Echocardiography
Donofrio, M.T. and Rychik, J. and Moon-Grady, A.J. and Puchalski, M.D. and Tworetzky, W. and Cuneo, B.F. and Abuhamad, A.Z. and Ayers, N.A. and Copel, J.A. and Gardiner, H.M. and Golding, F. and Freud, L.R. and Jaeggi, E.T. and Lee, W. and Miller, S. and Morris, S.A. and Peyvandi, S. and Schidlow, D.N. and Silverman, N.H.
DOI: 10.1016/j.echo.2015.11.012
2016

Serial prenatal and post-natal brain MRI demonstrates impact of congenital heart disease and cardiac surgery on brain growth and maturity.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Porayette P and Lim JM and Saini BS and Madathil S and Zhu MY and Jaeggi E and Grosse-Wortmann L and Yoo S and Macgowan C and Miller S and Seed M
2016

Neonatal Pain and Infection Relate to Smaller Cerebellum in Very Preterm Children at School Age.
The Journal of pediatrics
Ranger M and Zwicker JG and Chau CM and Park MT and Chakravarthy MM and Poskitt K and Miller SP and Bjornson BH and Tam EW and Chau V and Synnes AR and Grunau RE
DOI: 10.1016/j.jpeds.2015.04.055
PubMed: 25987534
08/2015

Tract-Based Spatial Statistics in Preterm-Born Neonates Predicts Cognitive and Motor Outcomes at 18 Months.
AJNR. American journal of neuroradiology
Duerden EG and Foong J and Chau V and Branson H and Poskitt KJ and Grunau RE and Synnes A and Zwicker JG and Miller SP
DOI: 10.3174/ajnr.a4312
PubMed: 25929880
08/2015

Neonatal seizures and brain imaging
Journal of Pediatric Neurology
Steven Miller and Sonia Bonifacio
DOI: 10.3233/jpn-2009-0269
07/2015

Neurodevelopmental outcomes after cardiac surgery in infancy.
Pediatrics
Gaynor JW and Stopp C and Wypij D and Andropoulos DB and Atallah J and Atz AM and Beca J and Donofrio MT and Duncan K and Ghanayem NS and Goldberg CS and Hövels-Gürich H and Ichida F and International Cardiac Collaborative on Neurodevelopment (ICCON) Investigators
DOI: 10.1542/peds.2014-3825
PubMed: 25917996
05/2015

Oxygen therapy for preterm neonates: the elusive optimal target.
JAMA pediatrics
Synnes A and Miller SP
DOI: 10.1001/jamapediatrics.2014.3664
PubMed: 25664537
04/2015

Reduced fetal cerebral oxygen consumption is associated with smaller brain size in fetuses with congenital heart disease.
Circulation
Sun L and Macgowan CK and Sled JG and Yoo SJ and Manlhiot C and Porayette P and Grosse-Wortmann L and Jaeggi E and McCrindle BW and Kingdom J and Hickey E and Miller S and Seed M
DOI: 10.1161/circulationaha.114.013051
PubMed: 25762062
04/2015

Magnetic resonance imaging (MRI) and prognostication in neonatal hypoxic-ischemic injury: a vignette-based study of Canadian specialty physicians.
Journal of child neurology
Bell E and Rasmussen LA and Mazer B and Shevell M and Miller SP and Synnes A and Yager JY and Majnemer A and Muhajarine N and Chouinard I and Racine E
DOI: 10.1177/0883073814531821
PubMed: 24789518
02/2015

Automatic segmentation of the hippocampus for preterm neonates from early-in-life to term-equivalent age.
NeuroImage. Clinical
Guo T and Winterburn JL and Pipitone J and Duerden EG and Park MT and Chau V and Poskitt KJ and Grunau RE and Synnes A and Miller SP and Mallar Chakravarty M
DOI: 10.1016/j.nicl.2015.07.019
PubMed: 26740912
2015

MRI reveals hemodynamic changes with acute maternal hyperoxygenation in human fetuses with and without congenital heart disease.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Porayette P and Sun L and Jaeggi E and Grosse-Wortmann L and Yoo S and Hickey EJ and Miller S and Macgowan C and Seed M
DOI: 10.1186/1532-429x-17-s1-o55
PubMed: 26701792
2015

Tract-based spatial statistics in preterm-born neonates predicts cognitive and motor outcomes at 18 months
American Journal of Neuroradiology
Duerden, E.G. and Foong, J. and Chau, V. and Branson, H. and Poskitt, K.J. and Grunau, R.E. and Synnes, A. and Zwicker, J.G. and Miller, S.P.
DOI: 10.3174/ajnr.A4312
2015

Stochastic process for white matter injury detection in preterm neonates
NeuroImage: Clinical
Cheng, I. and Miller, S.P. and Duerden, E.G. and Sun, K. and Chau, V. and Adams, E. and Poskitt, K.J. and Branson, H.M. and Basu, A.
DOI: 10.1016/j.nicl.2015.02.015
2015

Prediction of motor function in very preterm infants using connectome features and local synthetic instances
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Brown, C.J. and Miller, S.P. and Booth, B.G. and Poskitt, K.J. and Chau, V. and Synnes, A.R. and Zwicker, J.G. and Grunau, R.E. and Hamarneh, G.
DOI: 10.1007/978-3-319-24553-9_9
2015

Reduced fetal cerebral oxygen consumption is associated with smaller brain size in fetuses with congenital heart disease
Circulation
Sun, L. and Macgowan, C.K. and Sled, J.G. and Yoo, S.-J. and Manlhiot, C. and Porayette, P. and Grosse-Wortmann, L. and Jaeggi, E. and McCrindle, B.W. and Kingdom, J. and Hickey, E. and Miller, S. and Seed, M.
DOI: 10.1161/CIRCULATIONAHA.114.013051
2015

Early neonatal pain exposure and brain microstructure interact to predict neurodevelopmental outcomes at 18 months corrected age in children born very preterm
International Journal of Developmental Neuroscience
Jillian Vinall and Jill G. Zwicker and Ruth E. Grunau and Vann Chau and Kenneth J. Poskitt and Rollin Brant and Anne R. Synnes and Steven P. Miller
DOI: 10.1016/j.ijdevneu.2015.04.132
2015

Fetal haemodynamic assessment in a case of late-onset intrauterine growth restriction by phase contrast MRI and T2 mapping.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Zhu MY and Madathil S and Miller S and Windrim R and Macgowan C and Kingdom J and Seed M
DOI: 10.1186/1532-429x-17-s1-p27
2015

Reduced fetal cerebral oxygen consumption is associated with abnormal white matter in newborns with congenital heart disease.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Muthusami P and Madathil S and Blaser S and Jaeggi E and Grosse-Wortmann L and Yoo S and Kingdom J and Hickey EJ and Sled JG and Macgowan C and Miller S and Seed M
2015

Cerebral oxygen delivery in newborns with congenital heart disease by phase contrast MRI.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Lim JM and Kingdom T and Saini B and Blaser S and Grosse-Wortmann L and Yoo S and Hickey EJ and Macgowan C and Miller S and Seed M
DOI: 10.1186/1532-429x-17-s1-m9
2015

MRI reveals increased superior vena caval blood flow in human fetuses with congenital heart disease, abnormal placental pathology and neonatal brain white matter changes.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Madathil S and Sun L and Saini BS and Yoo S and Jaeggi E and Grosse-Wortmann L and Kingdom J and Hickey EJ and Miller S and Macgowan C and Seed M
DOI: 10.1186/1532-429x-17-s1-o92
2015

Assessment of MRI parameters for studying brain development in newborns with congenital heart disease.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Saini BS and Muthusami P and Madathil S and Lim JM and Macgowan C and Miller S and Seed M
2015

Society for Pediatric Research 2014 Presidential Address: The test of our progress.
Pediatric research
Miller SP
DOI: 10.1038/pr.2014.149
PubMed: 25397370
12/2014

Minimizing the risk of preoperative brain injury in neonates with aortic arch obstruction.
The Journal of pediatrics
Algra SO and Haas F and Poskitt KJ and Groenendaal F and Schouten AN and Jansen NJ and Azakie A and Gandhi S and Campbell A and Miller SP and McQuillen PS and de Vries LS
DOI: 10.1016/j.jpeds.2014.08.066
PubMed: 25306190
12/2014

Structural network analysis of brain development in young preterm neonates.
NeuroImage
Brown CJ and Miller SP and Booth BG and Andrews S and Chau V and Poskitt KJ and Hamarneh G
DOI: 10.1016/j.neuroimage.2014.07.030
PubMed: 25076107
11/2014

Further evidence for botulinum toxin A in cerebral palsy.
The Journal of pediatrics
Chau V and Fehlings D and Miller SP
DOI: 10.1016/j.jpeds.2014.03.041
PubMed: 24787538
07/2014

Preferential cephalic redistribution of left ventricular cardiac output during therapeutic hypothermia for perinatal hypoxic-ischemic encephalopathy.
The Journal of pediatrics
Hochwald O and Jabr M and Osiovich H and Miller SP and McNamara PJ and Lavoie PM
DOI: 10.1016/j.jpeds.2014.01.028
PubMed: 24582011
05/2014

Brain injury in premature neonates: A primary cerebral dysmaturation disorder?
Annals of neurology
Back SA and Miller SP
DOI: 10.1002/ana.24132
PubMed: 24615937
04/2014

Invasive procedures in preterm children: brain and cognitive development at school age.
Pediatrics
Vinall J and Miller SP and Bjornson BH and Fitzpatrick KP and Poskitt KJ and Brant R and Synnes AR and Cepeda IL and Grunau RE
DOI: 10.1542/peds.2013-1863
PubMed: 24534406
03/2014

Chorioamnionitis in the pathogenesis of brain injury in preterm infants.
Clinics in perinatology
Chau V and McFadden DE and Poskitt KJ and Miller SP
DOI: 10.1016/j.clp.2013.10.009
PubMed: 24524448
03/2014

Magnetic resonance imaging in the encephalopathic term newborn.
Current pediatric reviews
Chau V and Poskitt KJ and Dunham CP and Hendson G and Miller SP
DOI: 10.2174/157339631001140408120336
PubMed: 25055861
2014

Spatially adapted augmentation of age-specific atlas-based segmentation using patch-based priors
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Liu, M. and Seshamani, S. and Harrylock, L. and Kitsch, A. and Miller, S. and Chau, V. and Poskitt, K. and Rousseau, F. and Studholme, C.
DOI: 10.1117/12.2042426
2014

Abnormal brain maturation in preterm neonates associated with adverse developmental outcomes.
Neurology
Chau V and Synnes A and Grunau RE and Poskitt KJ and Brant R and Miller SP
DOI: 10.1212/01.wnl.0000437298.43688.b9
PubMed: 24212394
12/2013

MRI findings in infants with infantile spasms after neonatal hypoxic-ischemic encephalopathy.
Pediatric neurology
Gano D and Sargent MA and Miller SP and Connolly MB and Wong P and Glass HC and Poskitt KJ and Chau V
DOI: 10.1016/j.pediatrneurol.2013.08.007
PubMed: 24095571
12/2013

Neonatal pain-related stress, functional cortical activity and visual-perceptual abilities in school-age children born at extremely low gestational age.
Pain
Doesburg SM and Chau CM and Cheung TP and Moiseev A and Ribary U and Herdman AT and Miller SP and Cepeda IL and Synnes A and Grunau RE
DOI: 10.1016/j.pain.2013.04.009
PubMed: 23711638
10/2013

Resuscitation intensity at birth is associated with changes in brain metabolic development in preterm neonates.
Neuroradiology
Duerden EG and Brown-Lum M and Chau V and Poskitt KJ and Grunau RE and Synnes A and Miller SP
DOI: 10.1007/s00234-013-1243-9
PubMed: 23921419
09/2013

Parent behaviors moderate the relationship between neonatal pain and internalizing behaviors at 18 months corrected age in children born very prematurely.
Pain
Vinall J and Miller SP and Synnes AR and Grunau RE
DOI: 10.1016/j.pain.2013.05.050
PubMed: 23748079
09/2013

Visual function in preterm infants: visualizing the brain to improve prognosis.
Documenta ophthalmologica. Advances in ophthalmology
Chau V and Taylor MJ and Miller SP
DOI: 10.1007/s10633-013-9397-7
PubMed: 23761036
08/2013

Prenatal and postnatal inflammation in relation to cortisol levels in preterm infants at 18 months corrected age.
Journal of perinatology : official journal of the California Perinatal Association
Gover A and Chau V and Miller SP and Brant R and McFadden DE and Poskitt KJ and Synnes A and Weinberg J and Grunau RE
DOI: 10.1038/jp.2013.24
PubMed: 23558431
08/2013

Brain injury and development in newborns with critical congenital heart disease.
Neurology
Dimitropoulos A and McQuillen PS and Sethi V and Moosa A and Chau V and Xu D and Brant R and Azakie A and Campbell A and Barkovich AJ and Poskitt KJ and Miller SP
DOI: 10.1212/wnl.0b013e31829bfdcf
PubMed: 23771484
07/2013

Brain injury patterns in hypoglycemia in neonatal encephalopathy.
AJNR. American journal of neuroradiology
Wong DS and Poskitt KJ and Chau V and Miller SP and Roland E and Hill A and Tam EW
DOI: 10.3174/ajnr.a3423
PubMed: 23436054
07/2013

Evolution of pattern of injury and quantitative MRI on days 1 and 3 in term newborns with hypoxic-ischemic encephalopathy.
Pediatric research
Gano D and Chau V and Poskitt KJ and Hill A and Roland E and Brant R and Chalmers M and Miller SP
DOI: 10.1038/pr.2013.69
PubMed: 23618911
07/2013

Brain development in infants born preterm: looking beyond injury.
Seminars in pediatric neurology
Duerden EG and Taylor MJ and Miller SP
DOI: 10.1016/j.spen.2013.06.007
PubMed: 23948681
06/2013

Single-ventricle anatomy predicts delayed microstructural brain development.
Pediatric research
Sethi V and Tabbutt S and Dimitropoulos A and Harris KC and Chau V and Poskitt K and Campbell A and Azakie A and Xu D and Barkovich AJ and Miller SP and McQuillen PS
DOI: 10.1038/pr.2013.29
PubMed: 23407116
05/2013

Score for neonatal acute physiology-II and neonatal pain predict corticospinal tract development in premature newborns.
Pediatric neurology
Zwicker JG and Grunau RE and Adams E and Chau V and Brant R and Poskitt KJ and Synnes A and Miller SP
DOI: 10.1016/j.pediatrneurol.2012.10.016
PubMed: 23337005
02/2013

Slower postnatal growth is associated with delayed cerebral cortical maturation in preterm newborns.
Science translational medicine
Vinall J and Grunau RE and Brant R and Chau V and Poskitt KJ and Synnes AR and Miller SP
DOI: 10.1126/scitranslmed.3004666
PubMed: 23325801
01/2013

Paediatric neurology: improved care of the developing brain.
The Lancet. Neurology
Miller SP and Ferriero DM
DOI: 10.1016/s1474-4422(12)70292-2
PubMed: 23237895
01/2013

Neonatal pain-related stress predicts cortical thickness at age 7 years in children born very preterm.
PloS one
Ranger M and Chau CM and Garg A and Woodward TS and Beg MF and Bjornson B and Poskitt K and Fitzpatrick K and Synnes AR and Miller SP and Grunau RE
DOI: 10.1371/journal.pone.0076702
PubMed: 24204657
2013

Paediatric neurology: Improved care of the developing brain
The Lancet Neurology
Miller, S.P. and Ferriero, D.M.
DOI: 10.1016/S1474-4422(12)70292-2
2013

White matter injury detection in neonatal MRI
Proceedings of SPIE - The International Society for Optical Engineering
Cheng, I. and Hajari, N. and Firouzmanesh, A. and Shen, R. and Miller, S. and Poskitt, K. and Basu, A.
DOI: 10.1117/12.2006636
2013

Brain injury and development in newborns with critical congenital heart disease
Neurology
Dimitropoulos, A. and McQuillen, P.S. and Sethi, V. and Moosa, A. and Chau, V. and Xu, D. and Brant, R. and Azakie, A. and Campbell, A. and Barkovich, A.J. and Poskitt, K.J. and Miller, S.P.
DOI: 10.1212/WNL.0b013e31829bfdcf
2013

Brain injury patterns in hypoglycemia in neonatal encephalopathy
American Journal of Neuroradiology
Wong, D.S.T. and Poskitt, K.J. and Chau, V. and Miller, S.P. and Roland, E. and Hill, A. and Tam, E.W.Y.
DOI: 10.3174/ajnr.A3423
2013

Magnetic resonance imaging in hypoxic-ischemic encephalopathy: still a cool test.
Archives of pediatrics & adolescent medicine
Chau V and Poskitt KJ and Miller SP
DOI: 10.1001/archpediatrics.2012.579
PubMed: 22751888
07/2012

Neonatal pain in relation to postnatal growth in infants born very preterm.
Pain
Vinall J and Miller SP and Chau V and Brummelte S and Synnes AR and Grunau RE
DOI: 10.1016/j.pain.2012.02.007
PubMed: 22704600
07/2012

Single course of antenatal steroids did not alter cortisol in preterm infants up to 18 months.
Acta paediatrica (Oslo, Norway : 1992)
Gover A and Brummelte S and Synnes AR and Miller SP and Brant R and Weinberg J and Grunau RE
DOI: 10.1111/j.1651-2227.2012.02629.x
PubMed: 22313364
06/2012

Procedural pain and brain development in premature newborns.
Annals of neurology
Brummelte S and Grunau RE and Chau V and Poskitt KJ and Brant R and Vinall J and Gover A and Synnes AR and Miller SP
DOI: 10.1002/ana.22267
PubMed: 22374882
03/2012

Postnatal infection is associated with widespread abnormalities of brain development in premature newborns.
Pediatric research
Chau V and Brant R and Poskitt KJ and Tam EW and Synnes A and Miller SP
DOI: 10.1038/pr.2011.40
PubMed: 22278180
03/2012

Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants.
Annals of neurology
Buser JR and Maire J and Riddle A and Gong X and Nguyen T and Nelson K and Luo NL and Ren J and Struve J and Sherman LS and Miller SP and Chau V and Hendson G and Ballabh P and Grafe MR and Back SA
DOI: 10.1002/ana.22627
PubMed: 22275256
01/2012

Hypoxic-Ischemic Brain Injury in the Term Newborn
Swaiman's Pediatric Neurology
Steven P. Miller and Donna M. Ferriero
DOI: 10.1016/b978-1-4377-0435-8.00017-2
2012

Brain Injury in Newborn Infants with Congenital Heart Disease
Acquired Brain Injury in the Fetus and Newborn
2012

Clinical Approach to Term Encephalopathy
Acquired Brain Injury in the Fetus and Newborn
2012

Early inflammation in the absence of overt infection in preterm neonates exposed to intensive care.
Cytokine
Chang BA and Huang Q and Quan J and Chau V and Ladd M and Kwan E and McFadden DE and Lacaze-Masmonteil T and Miller SP and Lavoie PM
DOI: 10.1016/j.cyto.2011.08.028
PubMed: 21940177
12/2011

Preterm cerebellar growth impairment after postnatal exposure to glucocorticoids.
Science translational medicine
Tam EW and Chau V and Ferriero DM and Barkovich AJ and Poskitt KJ and Studholme C and Fok ED and Grunau RE and Glidden DV and Miller SP
DOI: 10.1126/scitranslmed.3002884
PubMed: 22013125
10/2011

Infection and white matter injury in infants with congenital cardiac disease.
Cardiology in the young
Glass HC and Bowman C and Chau V and Moosa A and Hersh AL and Campbell A and Poskitt K and Azakie A and Barkovich AJ and Miller SP and McQuillen PS
DOI: 10.1017/s1047951111000473
PubMed: 21554828
10/2011

Magnetoencephalography reveals slowing of resting peak oscillatory frequency in children born very preterm.
Pediatric research
Doesburg SM and Ribary U and Herdman AT and Moiseev A and Cheung T and Miller SP and Poskitt KJ and Weinberg H and Whitfield MF and Synnes A and Grunau RE
DOI: 10.1203/pdr.0b013e3182225a9e
PubMed: 21544009
08/2011

Correspondence on ''clinical seizures in neonatal hypoxic-ischemic encephalopathy have no independent impact on neurodevelopmental outcome: secondary analyses of data from the neonatal research network hypothermia trial''.
Journal of child neurology
Glass HC and Ferriero DM and Miller SP
DOI: 10.1177/0883073811399801
PubMed: 21493809
04/2011

The role of hypoxia-ischemia in term newborns with arterial stroke.
Pediatric neurology
Michoulas A and Basheer SN and Roland EH and Poskitt K and Miller S and Hill A
DOI: 10.1016/j.pediatrneurol.2010.10.013
PubMed: 21397165
04/2011

Sildenafil citrate therapy for severe early-onset intrauterine growth restriction.
BJOG : an international journal of obstetrics and gynaecology
von Dadelszen P and Dwinnell S and Magee LA and Carleton BC and Gruslin A and Lee B and Lim KI and Liston RM and Miller SP and Rurak D and Sherlock RL and Skoll MA and Wareing MM and Research into Advanced Fetal Diagnosis and Therapy (RAFT) Group
DOI: 10.1111/j.1471-0528.2010.02879.x
PubMed: 21392225
04/2011

The Cerebral Palsy Demonstration Project: a multidimensional research approach to cerebral palsy.
Seminars in pediatric neurology
Shevell M and Miller SP and Scherer SW and Yager JY and Fehlings MG
DOI: 10.1016/j.spen.2011.02.004
PubMed: 21575839
03/2011

Differential effects of intraventricular hemorrhage and white matter injury on preterm cerebellar growth.
The Journal of pediatrics
Tam EW and Miller SP and Studholme C and Chau V and Glidden D and Poskitt KJ and Ferriero DM and Barkovich AJ
DOI: 10.1016/j.jpeds.2010.09.005
PubMed: 20961562
03/2011

Altered long-range alpha-band synchronization during visual short-term memory retention in children born very preterm.
NeuroImage
Doesburg SM and Ribary U and Herdman AT and Miller SP and Poskitt KJ and Moiseev A and Whitfield MF and Synnes A and Grunau RE
DOI: 10.1016/j.neuroimage.2010.10.044
PubMed: 20974268
02/2011

Magnesium Sulphate for Fetal Neuroprotection
Journal of Obstetrics and Gynaecology Canada
Magee, L. and Sawchuck, D. and Synnes, A. and von Dadelszen, P. and Basso, M. and Crane, J.M. and Doyle, L. and Ehman, W. and Gagnon, R. and Grobman, W. and Helewa, M. and Joseph, K.S. and Jocelyne Martel, M. and Miller, S. and Okun, N. and Rouse, D. and Senikas, V. and Sherlock, R. and Skoll, A. and Smith, G. and Wagner, B. and Wavrant, S. and Douglas Wilson, R. and Hutcheon, J. and Gagnon, R. and Hudon, L. and Basso, M. and Bos, H. and Crane, J.M. and Davies, G. and Delisle, M.-F. and Menticoglou, S. and Mundle, W. and Ouellet, A. and Pressey, T. and Pylypjuk, C. and Roggensack, A. and Sanderson, F.L.
DOI: 10.1016/S1701-2163(16)34886-1
2011

Infection and white matter injury in infants with congenital cardiac disease
Cardiology in the Young
Glass, H.C. and Bowman, C. and Chau, V. and Moosa, A. and Hersh, A.L. and Campbell, A. and Poskitt, K. and Azakie, A. and Barkovich, A.J. and Miller, S.P. and McQuillen, P.S.
DOI: 10.1017/S1047951111000473
2011

Magnesium sulphate for fetal neuroprotection,Recours au sulfate de magnésium à des fins de neuroprotection fœtale
Journal of Obstetrics and Gynaecology Canada
Magee, L. and Sawchuck, D. and Synnes, A. and von Dadelszen, P. and Basso, M. and Crane, J.M. and Doyle, L. and Ehman, W. and Gagnon, R. and Grobman, W. and Helewa, M. and Joseph, K.S. and Jocelyne Martel, M. and Miller, S. and Okun, N. and Rouse, D. and Senikas, V. and Sherlock, R. and Skoll, A. and Smith, G. and Wagner, B. and Wavrant, S. and Douglas Wilson, R. and Hutcheon, J. and Gagnon, R. and Hudon, L. and Basso, M. and Bos, H. and Crane, J.M. and Davies, G. and Delisle, M.-F. and Menticoglou, S. and Mundle, W. and Ouellet, A. and Pressey, T. and Pylypjuk, C. and Roggensack, A. and Sanderson, F.L.
DOI: 10.1016/S1701-2163(16)34887-3
2011

Magnetoencephalography reveals slowing of resting peak oscillatory frequency in children born very preterm
Pediatric Research
Doesburg, S.M. and Ribary, U. and Herdman, A.T. and Moiseev, A. and Cheung, T. and Miller, S.P. and Poskitt, K.J. and Weinberg, H. and Whitfield, M.F. and Synnes, A. and Grunau, R.E.
DOI: 10.1203/PDR.0b013e3182225a9e
2011

Extreme premature birth is not associated with impaired development of brain microstructure.
The Journal of pediatrics
Bonifacio SL and Glass HC and Chau V and Berman JI and Xu D and Brant R and Barkovich AJ and Poskitt KJ and Miller SP and Ferriero DM
DOI: 10.1016/j.jpeds.2010.05.026
PubMed: 20598316
11/2010

Imaging selective vulnerability in the developing nervous system.
Journal of anatomy
Ferriero DM and Miller SP
DOI: 10.1111/j.1469-7580.2010.01226.x
PubMed: 20408904
10/2010

Clinically silent preoperative brain injuries do not worsen with surgery in neonates with congenital heart disease.
The Journal of thoracic and cardiovascular surgery
Block AJ and McQuillen PS and Chau V and Glass H and Poskitt KJ and Barkovich AJ and Esch M and Soulikias W and Azakie A and Campbell A and Miller SP
DOI: 10.1016/j.jtcvs.2010.03.035
PubMed: 20434174
09/2010

Tractography-based quantitation of corticospinal tract development in premature newborns.
The Journal of pediatrics
Adams E and Chau V and Poskitt KJ and Grunau RE and Synnes A and Miller SP
DOI: 10.1016/j.jpeds.2009.12.030
PubMed: 20227731
06/2010

Congenital heart disease and brain development.
Annals of the New York Academy of Sciences
McQuillen PS and Miller SP
DOI: 10.1111/j.1749-6632.2009.05116.x
PubMed: 20146691
01/2010

Reconstruction of a geometrically correct diffusion tensor image of a moving human fetal brain
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Kim, K. and Habas, P.A. and Rousseau, F. and Glenn, O.A. and Barkovich, A.J. and Koob, M. and Dietemann, J.-L. and Robinson, A.J. and Poskitt, K.J. and Miller, S.P. and Studholme, C.
DOI: 10.1117/12.844542
2010

The spectrum of abnormal neurologic outcomes subsequent to term intrapartum asphyxia.
Pediatric neurology
Al-Macki N and Miller SP and Hall N and Shevell M
DOI: 10.1016/j.pediatrneurol.2009.06.001
PubMed: 19931160
12/2009

From selective vulnerability to connectivity: insights from newborn brain imaging.
Trends in neurosciences
Miller SP and Ferriero DM
DOI: 10.1016/j.tins.2009.05.010
PubMed: 19712981
09/2009

Clinical Neonatal Seizures are Independently Associated with Outcome in Infants at Risk for Hypoxic-Ischemic Brain Injury.
The Journal of pediatrics
Glass HC and Glidden D and Jeremy RJ and Barkovich AJ and Ferriero DM and Miller SP
DOI: 10.1016/j.jpeds.2009.03.040
PubMed: 19540512
09/2009

Effect of chorioamnionitis on brain development and injury in premature newborns.
Annals of neurology
Chau V and Poskitt KJ and McFadden DE and Bowen-Roberts T and Synnes A and Brant R and Sargent MA and Soulikias W and Miller SP
DOI: 10.1002/ana.21713
PubMed: 19743455
08/2009

Delayed recognition of initial stroke in children: need for increased awareness.
Pediatrics
Srinivasan J and Miller SP and Phan TG and Mackay MT
DOI: 10.1542/peds.2008-3544
PubMed: 19620205
08/2009

Cerebellar development in the preterm neonate: effect of supratentorial brain injury.
Pediatric research
Tam EW and Ferriero DM and Xu D and Berman JI and Vigneron DB and Barkovich AJ and Miller SP
DOI: 10.1203/pdr.0b013e3181a1fb3d
PubMed: 19287350
07/2009

Neonatal watershed brain injury on magnetic resonance imaging correlates with verbal IQ at 4 years.
Pediatrics
Steinman KJ and Gorno-Tempini ML and Glidden DV and Kramer JH and Miller SP and Barkovich AJ and Ferriero DM
DOI: 10.1542/peds.2008-1203
PubMed: 19255035
03/2009

Systematic review of biomarkers of brain injury in term neonatal encephalopathy.
Pediatric neurology
Ramaswamy V and Horton J and Vandermeer B and Buscemi N and Miller S and Yager J
DOI: 10.1016/j.pediatrneurol.2008.09.026
PubMed: 19218035
03/2009

Advanced neuroimaging techniques for the term newborn with encephalopathy.
Pediatric neurology
Chau V and Poskitt KJ and Miller SP
DOI: 10.1016/j.pediatrneurol.2008.09.012
PubMed: 19218031
03/2009

Comparison of computer tomography and magnetic resonance imaging scans on the third day of life in term newborns with neonatal encephalopathy.
Pediatrics
Chau V and Poskitt KJ and Sargent MA and Lupton BA and Hill A and Roland E and Miller SP
DOI: 10.1542/peds.2008-0283
PubMed: 19117898
01/2009

Quantitative fiber tracking analysis of the optic radiation correlated with visual performance in premature newborns.
AJNR. American journal of neuroradiology
Berman JI and Glass HC and Miller SP and Mukherjee P and Ferriero DM and Barkovich AJ and Vigneron DB and Henry RG
DOI: 10.3174/ajnr.a1304
PubMed: 18832665
01/2009

White matter injury in term newborns with neonatal encephalopathy.
Pediatric research
Li AM and Chau V and Poskitt KJ and Sargent MA and Lupton BA and Hill A and Roland E and Miller SP
DOI: 10.1203/pdr.0b013e31818912d2
PubMed: 18787422
01/2009

Preventing brain injury in newborns with congenital heart disease: brain imaging and innovative trial designs.
Stroke
Sherlock RL and McQuillen PS and Miller SP and aCCENT
DOI: 10.1161/strokeaha.108.522664
PubMed: 18988911
01/2009

Neurocognitive outcomes of term infants with perinatal asphyxia
Fetal and Neonatal Brain Injury, Fourth Edition
Miller, S.P. and Latal, B.
DOI: 10.1017/CBO9780511581281.050
2009

Preventing brain injury in newborns with congenital heart disease: Brain imaging and innovative trial designs
Stroke
Sherlock, R.L. and McQuillen, P.S. and Miller, S.P.
DOI: 10.1161/STROKEAHA.108.522664
2009

Neonatal seizures and brain imaging
Journal of Pediatric Neurology
Bonifacio, S.L. and Miller, S.P.
DOI: 10.3233/JPN-2009-0269
2009

Quantitative fiber tracking analysis of the optic radiation correlated with visual performance in premature newborns
American Journal of Neuroradiology
Berman, J.I. and Glass, H.C. and Miller, S.P. and Mukherjee, P. and Ferriero, D.M. and Barkovich, A.J. and Vigneron, D.B. and Henry, R.G.
DOI: 10.3174/ajnr.A1304
2009

White matter injury in term newborns with neonatal encephalopathy
Pediatric Research
Li, A.M. and Chau, V. and Poskitt, K.J. and Sargent, M.A. and Lupton, B.A. and Hill, A. and Roland, E. and Miller, S.P.
DOI: 10.1203/PDR.0b013e31818912d2
2009

Controversies and Advances in Neonatal Neurology: Overview
Pediatric Neurology
Yager, J.Y. and Miller, S.P.
DOI: 10.1016/j.pediatrneurol.2008.12.001
2009

Cerebellar development in the preterm neonate: Effect of supratentorial brain injury
Pediatric Research
Tam, E.W.Y. and Ferriero, D.M. and Xu, D. and Berman, J.I. and Vigneron, D.B. and Barkovich, A.J. and Miller, S.P.
DOI: 10.1203/PDR.0b013e3181a1fb3d
2009

Recurrent postnatal infections are associated with progressive white matter injury in premature infants.
Pediatrics
Glass HC and Bonifacio SL and Chau V and Glidden D and Poskitt K and Barkovich AJ and Ferriero DM and Miller SP
DOI: 10.1542/peds.2007-2184
PubMed: 18676547
08/2008

Brain metabolite levels assessed by lactate-edited MR spectroscopy in premature neonates with and without pentobarbital sedation.
AJNR. American journal of neuroradiology
Wang ZJ and Vigneron DB and Miller SP and Mukherjee P and Charlton NN and Lu Y and Barkovich AJ
DOI: 10.3174/ajnr.a0912
PubMed: 18184837
04/2008

White-matter injury is associated with impaired gaze in premature infants.
Pediatric neurology
Glass HC and Fujimoto S and Ceppi-Cozzio C and Bartha AI and Vigneron DB and Barkovich AJ and Glidden DV and Ferriero DM and Miller SP
DOI: 10.1016/j.pediatrneurol.2007.08.019
PubMed: 18054686
01/2008

Brain metabolite levels assessed by lactate-edited MR spectroscopy in premature neonates with and without pentobarbital sedation
American Journal of Neuroradiology
Wang, Z.J. and Vigneron, D.B. and Miller, S.P. and Mukherjee, P. and Charlton, N.N. and Lu, Y. and Barkovich, A.J.
DOI: 10.3174/ajnr.A0912
2008

Abnormal brain development in newborns with congenital heart disease.
The New England journal of medicine
Miller SP and McQuillen PS and Hamrick S and Xu D and Glidden DV and Charlton N and Karl T and Azakie A and Ferriero DM and Barkovich AJ and Vigneron DB
DOI: 10.1056/nejmoa067393
PubMed: 17989385
11/2007

Neurology of congenital heart disease: insight from brain imaging.
Archives of disease in childhood. Fetal and neonatal edition
Miller SP and McQuillen PS
DOI: 10.1136/adc.2006.108845
PubMed: 17848505
11/2007

Brainstem involvement in neonatal herpes simplex virus type 2 encephalitis.
Pediatrics
Pelligra G and Lynch N and Miller SP and Sargent MA and Osiovich H
DOI: 10.1542/peds.2006-3757
PubMed: 17671049
08/2007

Newborn brain injury: looking back to the fetus.
Annals of neurology
Miller SP
DOI: 10.1002/ana.21124
PubMed: 17444513
04/2007

Regional and central venous oxygen saturation monitoring following pediatric cardiac surgery: concordance and association with clinical variables.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
McQuillen PS and Nishimoto MS and Bottrell CL and Fineman LD and Hamrick SE and Glidden DV and Azakie A and Adatia I and Miller SP
DOI: 10.1097/01.pcc.0000257101.37171.be
PubMed: 17273125
03/2007

Temporal and anatomic risk profile of brain injury with neonatal repair of congenital heart defects.
Stroke
McQuillen PS and Barkovich AJ and Hamrick SE and Perez M and Ward P and Glidden DV and Azakie A and Karl T and Miller SP
DOI: 10.1161/01.str.0000247941.41234.90
PubMed: 17261728
02/2007

The normal neonatal brain: MR imaging, diffusion tensor imaging, and 3D MR spectroscopy in healthy term neonates.
AJNR. American journal of neuroradiology
Bartha AI and Yap KR and Miller SP and Jeremy RJ and Nishimoto M and Vigneron DB and Barkovich AJ and Ferriero DM
DOI: 10.3174/ajnr.a0521
PubMed: 17569948
2007

The normal neonatal brain: MR imaging, diffusion tensor imaging, and 3D MR spectroscopy in healthy term neonates
American Journal of Neuroradiology
Bartha, A.I. and Yap, K.R.L. and Miller, S.P. and Jeremy, R.J. and Nishimoto, M. and Vigneron, D.B. and Barkovich, A.J. and Ferriero, D.M.
DOI: 10.3174/ajnr.A0521
2007

Abnormal brain development in newborns with congenital heart disease
New England Journal of Medicine
Miller, S.P. and McQuillen, P.S. and Hamrick, S. and Xu, D. and Glidden, D.V. and Charlton, N. and Karl, T. and Azakie, A. and Ferriero, D.M. and Barkovich, A.J. and Vigneron, D.B.
DOI: 10.1056/NEJMoa067393
2007

Temporal and anatomic risk profile of brain injury with neonatal repair of congenital heart defects
Stroke
McQuillen, P.S. and Barkovich, A.J. and Hamrick, S.E.G. and Perez, M. and Ward, P. and Glidden, D.V. and Azakie, A. and Karl, T. and Miller, S.P.
DOI: 10.1161/01.STR.0000247941.41234.90
2007

Regional and central venous oxygen saturation monitoring following pediatric cardiac surgery: Concordance and association with clinical variables
Pediatric Critical Care Medicine
McQuillen, P.S. and Nishimoto, M.S. and Bottrell, C.L. and Fineman, L.D. and Hamrick, S.E. and Glidden, D.V. and Azakie, A. and Adatia, I. and Miller, S.P.
DOI: 10.1097/01.PCC.0000257101.37171.BE
2007

Neonatal brain injuries
Neurobiology of Disease
Miller, S.P. and Ferriero, D.M.
DOI: 10.1016/B978-012088592-3/50056-6
2007

Neonatal Brain Injuries
Neurobiology of Disease
Steven P. Miller and Donna M. Ferriero
DOI: 10.1016/b978-012088592-3/50056-6
2007

Does perinatal asphyxia impair cognitive function without cerebral palsy?
Archives of disease in childhood. Fetal and neonatal edition
Gonzalez FF and Miller SP
DOI: 10.1136/adc.2005.092445
PubMed: 17056843
11/2006

Candidate gene polymorphisms do not differ between newborns with stroke and normal controls.
Stroke
Miller SP and Wu YW and Lee J and Lammer EJ and Iovannisci DM and Glidden DV and Bonifacio SL and Collins A and Shaw GM and Barkovich AJ and Ferriero DM
DOI: 10.1161/01.str.0000244810.91105.c9
PubMed: 17008620
11/2006

Prolonged indomethacin exposure is associated with decreased white matter injury detected with magnetic resonance imaging in premature newborns at 24 to 28 weeks' gestation at birth.
Pediatrics
Miller SP and Mayer EE and Clyman RI and Glidden DV and Hamrick SE and Barkovich AJ
DOI: 10.1542/peds.2005-1767
PubMed: 16651316
05/2006

Pyramidal tract maturation after brain injury in newborns with heart disease.
Annals of neurology
Partridge SC and Vigneron DB and Charlton NN and Berman JI and Henry RG and Mukherjee P and McQuillen PS and Karl TR and Barkovich AJ and Miller SP
DOI: 10.1002/ana.20772
PubMed: 16450369
04/2006

MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy.
AJNR. American journal of neuroradiology
Barkovich AJ and Miller SP and Bartha A and Newton N and Hamrick SE and Mukherjee P and Glenn OA and Xu D and Partridge JC and Ferriero DM and Vigneron DB
PubMed: 16551990
03/2006

Balloon atrial septostomy is associated with preoperative stroke in neonates with transposition of the great arteries.
Circulation
McQuillen PS and Hamrick SE and Perez MJ and Barkovich AJ and Glidden DV and Karl TR and Teitel D and Miller SP
DOI: 10.1161/circulationaha.105.566752
PubMed: 16401771
01/2006

Neonatal Encephalopathy
Current Therapy in Neurologic Disease
Steven P. Miller
DOI: 10.1016/b978-0-323-03432-6.50026-x
2006

Balloon atrial septostomy is associated with preoperative stroke in neonates with transposition of the great arteries
Circulation
McQuillen, P.S. and Hamrick, S.E.G. and Perez, M.J. and Barkovich, A.J. and Glidden, D.V. and Karl, T.R. and Teitel, D. and Miller, S.P.
DOI: 10.1161/CIRCULATIONAHA.105.566752
2006

Candidate gene polymorphisms do not differ between newborns with stroke and normal controls
Stroke
Miller, S.P. and Wu, Y.W. and Lee, J. and Lammer, E.J. and Iovannisci, D.M. and Glidden, D.V. and Bonifacio, S.L. and Collins, A. and Shaw, G.M. and Barkovich, A.J. and Ferriero, D.M.
DOI: 10.1161/01.STR.0000244810.91105.c9
2006

Appendicitis in the child with a ventriculo-peritoneal shunt: a 30-year review
Journal of Pediatric Surgery
Ein, S.H. and Miller, S. and Rutka, J.T.
DOI: 10.1016/j.jpedsurg.2006.03.004
2006

MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy
American Journal of Neuroradiology
Barkovich, A.J. and Miller, S.P. and Bartha, A. and Newton, N. and Hamrick, S.E.G. and Mukherjee, P. and Glenn, O.A. and Xu, D. and Partridge, J.C. and Ferriero, D.M. and Vigneron, D.B.
2006

Neonatal encephalopathy
Current Therapy in Neurologic Disease
Miller, S.P.
DOI: 10.1016/B9780323034326.50026X
2006

Early brain injury in premature newborns detected with magnetic resonance imaging is associated with adverse early neurodevelopmental outcome.
The Journal of pediatrics
Miller SP and Ferriero DM and Leonard C and Piecuch R and Glidden DV and Partridge JC and Perez M and Mukherjee P and Vigneron DB and Barkovich AJ
DOI: 10.1016/j.jpeds.2005.06.033
PubMed: 16291350
11/2005

Tractography-based quantitation of diffusion tensor imaging parameters in white matter tracts of preterm newborns.
Journal of magnetic resonance imaging : JMRI
Partridge SC and Mukherjee P and Berman JI and Henry RG and Miller SP and Lu Y and Glenn OA and Ferriero DM and Barkovich AJ and Vigneron DB
DOI: 10.1002/jmri.20410
PubMed: 16161075
10/2005

Quantitative diffusion tensor MRI fiber tractography of sensorimotor white matter development in premature infants.
NeuroImage
Berman JI and Mukherjee P and Partridge SC and Miller SP and Ferriero DM and Barkovich AJ and Vigneron DB and Henry RG
DOI: 10.1016/j.neuroimage.2005.05.018
PubMed: 15978841
10/2005

Cerebral oxygen balance is impaired during repair of aortic coarctation in infants and children.
The Journal of thoracic and cardiovascular surgery
Azakie A and Muse J and Gardner M and Skidmore KL and Miller SP and Karl TR and McQuillen PS
DOI: 10.1016/j.jtcvs.2005.04.015
PubMed: 16153936
09/2005

Comparing microstructural and macrostructural development of the cerebral cortex in premature newborns: Diffusion tensor imaging versus cortical gyration
NeuroImage
Amy R. deIpolyi and Pratik Mukherjee and Kanwar Gill and Roland G. Henry and Savannah C. Partridge and Srivathsa Veeraraghavan and Hua Jin and Ying Lu and Steven P. Miller and Donna M. Ferriero and Daniel B. Vigneron and A. James Barkovich
DOI: 10.1016/j.neuroimage.2005.04.027
09/2005

Patterns of brain injury in term neonatal encephalopathy.
The Journal of pediatrics
Miller SP and Ramaswamy V and Michelson D and Barkovich AJ and Holshouser B and Wycliffe N and Glidden DV and Deming D and Partridge JC and Wu YW and Ashwal S and Ferriero DM
DOI: 10.1016/j.jpeds.2004.12.026
PubMed: 15812446
04/2005

Infant botulism, type F, presenting at 54 hours of life.
Pediatric neurology
Keet CA and Fox CK and Margeta M and Marco E and Shane AL and Dearmond SJ and Strober JB and Miller SP
DOI: 10.1016/j.pediatrneurol.2004.09.003
PubMed: 15730901
03/2005

Type I spinal muscular atrophy can mimic sensory-motor axonal neuropathy.
Journal of child neurology
Anagnostou E and Miller SP and Guiot MC and Karpati G and Simard L and Dilenge ME and Shevell MI
DOI: 10.1177/08830738050200022101
PubMed: 15794183
02/2005

Perinatal stroke in term infants with neonatal encephalopathy [2] (multiple letters)
Neurology
Cowan, F.M. and Mercuri, E. and Rutherford, M.A. and Ferriero, D.M. and Ramaswamy, V. and Miller, S.P. and Barkovich, A.J. and Partridge, J.C.
DOI: 10.1212/wnl.64.3.579-a
2005

Neonatal encephalopathy: association of cytokines with MR spectroscopy and outcome.
Pediatric research
Bartha AI and Foster-Barber A and Miller SP and Vigneron DB and Glidden DV and Barkovich AJ and Ferriero DM
DOI: 10.1203/01.pdr.0000144819.45689.bb
PubMed: 15496611
12/2004

Trends in severe brain injury and neurodevelopmental outcome in premature newborn infants: the role of cystic periventricular leukomalacia.
The Journal of pediatrics
Hamrick SE and Miller SP and Leonard C and Glidden DV and Goldstein R and Ramaswamy V and Piecuch R and Ferriero DM
DOI: 10.1016/j.jpeds.2004.05.042
PubMed: 15520756
11/2004

Single-shot fast spin-echo diffusion tensor imaging of the brain and spine with head and phased array coils at 1.5 T and 3.0 T.
Magnetic resonance imaging
Xu D and Henry RG and Mukherjee P and Carvajal L and Miller SP and Barkovich AJ and Vigneron DB
DOI: 10.1016/j.mri.2004.01.075
PubMed: 15234443
07/2004

Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newborns.
NeuroImage
Partridge SC and Mukherjee P and Henry RG and Miller SP and Berman JI and Jin H and Lu Y and Glenn OA and Ferriero DM and Barkovich AJ and Vigneron DB
DOI: 10.1016/j.neuroimage.2004.02.038
PubMed: 15219602
07/2004

Early laminar organization of the human cerebrum demonstrated with diffusion tensor imaging in extremely premature infants.
NeuroImage
Maas LC and Mukherjee P and Carballido-Gamio J and Veeraraghavan S and Miller SP and Partridge SC and Henry RG and Barkovich AJ and Vigneron DB
DOI: 10.1016/j.neuroimage.2004.02.035
PubMed: 15219585
07/2004

Perinatal stroke in term infants with neonatal encephalopathy.
Neurology
Ramaswamy V and Miller SP and Barkovich AJ and Partridge JC and Ferriero DM
DOI: 10.1212/01.wnl.0000129909.77753.c4
PubMed: 15184620
06/2004

Preoperative brain injury in newborns with transposition of the great arteries.
The Annals of thoracic surgery
Miller SP and McQuillen PS and Vigneron DB and Glidden DV and Barkovich AJ and Ferriero DM and Hamrick SE and Azakie A and Karl TR
DOI: 10.1016/j.athoracsur.2003.10.084
PubMed: 15111170
05/2004

Clinical signs predict 30-month neurodevelopmental outcome after neonatal encephalopathy.
American journal of obstetrics and gynecology
Miller SP and Latal B and Clark H and Barnwell A and Glidden D and Barkovich AJ and Ferriero DM and Partridge JC
DOI: 10.1016/s0002-9378(03)00908-6
PubMed: 14749642
01/2004

Nucleated red blood cell counts [2] (multiple letters)
Pediatric Neurology
Breningstall, G.N. and Miller, S.P. and Hamrick, S.E.G. and Partridge, J.C.
DOI: 10.1016/j.pediatrneurol.2004.03.001
2004

Clinical signs predict 30-month neurodevelopmental outcome after neonatal encephalopathy
American Journal of Obstetrics and Gynecology
Miller, S.P. and Latal, B. and Clark, H. and Barnwell, A. and Glidden, D. and Barkovich, A.J. and Ferriero, D.M. and Partridge, J.C.
DOI: 10.1016/S0002-9378(03)00908-6
2004

Perinatal stroke in term infants with neonatal encephalopathy
Neurology
Ramaswamy, V. and Miller, S.P. and Barkovich, A.J. and Partridge, J.C. and Ferriero, D.M.
DOI: 10.1212/01.WNL.0000129909.77753.C4
2004

Neonatal encephalopathy: Association of cytokines with MR spectroscopy and outcome
Pediatric Research
Bartha, A.I. and Foster-Barber, A. and Miller, S.P. and Vigneron, D.B. and Glidden, D.V. and Barkovich, A.J. and Ferriero, D.M.
DOI: 10.1203/01.PDR.0000144819.45689.BB
2004

DTI-based three-dimensional tractography detects differences in the pyramidal tracts of infants and children with congenital hemiparesis.
Journal of magnetic resonance imaging : JMRI
Glenn OA and Henry RG and Berman JI and Chang PC and Miller SP and Vigneron DB and Barkovich AJ
DOI: 10.1002/jmri.10420
PubMed: 14635148
12/2003

Nucleated red blood cell counts: not associated with brain injury or outcome.
Pediatric neurology
Hamrick SE and Miller SP and Newton NR and Parer JT and Ferriero DM and Barkovich AJ and Partridge JC
DOI: 10.1016/s0887-8994(03)00266-2
PubMed: 14643387
10/2003

Comparing the diagnosis of white matter injury in premature newborns with serial MR imaging and transfontanel ultrasonography findings.
AJNR. American journal of neuroradiology
Miller SP and Cozzio CC and Goldstein RB and Ferriero DM and Partridge JC and Vigneron DB and Barkovich AJ
PubMed: 13679289
09/2003

Intraventricular hemorrhage in term neonates caused by sinovenous thrombosis.
Annals of neurology
Wu YW and Hamrick SE and Miller SP and Haward MF and Lai MC and Callen PW and Barkovich AJ and Ferriero DM
DOI: 10.1002/ana.10619
PubMed: 12838529
07/2003

Encephalopathy as a predictor of magnetic resonance imaging abnormalities in asphyxiated newborns.
Pediatric neurology
Kaufman SA and Miller SP and Ferriero DM and Glidden DH and Barkovich AJ and Partridge JC
DOI: 10.1016/s0887-8994(03)00015-8
PubMed: 12878294
05/2003

Comparing the diagnosis of white matter injury in premature newborns with serial MR imaging and transfontanel ultrasonography findings
American Journal of Neuroradiology
Miller, S.P. and Cozzio, C.C. and Goldstein, R.B. and Ferriero, D.M. and Partridge, J.C. and Vigneron, D.B. and Barkovich, A.J.
2003

Encephalopathy as a predictor of magnetic resonance imaging abnormalities in asphyxiated newborns
Pediatric Neurology
Kaufman, S.A. and Miller, S.P. and Ferriero, D.M. and Glidden, D.H. and Barkovich, A.J. and Partridge, J.C.
DOI: 10.1016/S0887-8994(03)00015-8
2003

Nucleated Red Blood Cell Counts: Not Associated with Brain Injury or Outcome
Pediatric Neurology
Hamrick, S.E.G. and Miller, S.P. and Newton, N.R. and Parer, J.T. and Ferriero, D.M. and Barkovich, A.J. and Partridge, J.C.
DOI: 10.1016/S0887-8994(03)00266-2
2003

Serial quantitative diffusion tensor MRI of the premature brain: development in newborns with and without injury.
Journal of magnetic resonance imaging : JMRI
Miller SP and Vigneron DB and Henry RG and Bohland MA and Ceppi-Cozzio C and Hoffman C and Newton N and Partridge JC and Ferriero DM and Barkovich AJ
DOI: 10.1002/jmri.10205
PubMed: 12451575
12/2002

Practice parameter: neuroimaging of the neonate: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society.
Neurology
Miller S and Ferriero D and Barkovich AJ and Silverstein F
DOI: 10.1212/wnl.59.10.1663
PubMed: 12451226
11/2002

Multiple risk factors in neonatal sinovenous thrombosis.
Neurology
Wu YW and Miller SP and Chin K and Collins AE and Lomeli SC and Chuang NA and Barkovich AJ and Ferriero DM
DOI: 10.1212/wnl.59.3.438
PubMed: 12177381
08/2002

Predictors of 30-month outcome after perinatal depression: role of proton MRS and socioeconomic factors.
Pediatric research
Miller SP and Newton N and Ferriero DM and Partridge JC and Glidden DV and Barnwell A and Chuang NA and Vigneron DB and Barkovich AJ
DOI: 10.1203/00006450-200207000-00014
PubMed: 12084850
07/2002

Seizure-associated brain injury in term newborns with perinatal asphyxia.
Neurology
Miller SP and Weiss J and Barnwell A and Ferriero DM and Latal-Hajnal B and Ferrer-Rogers A and Newton N and Partridge JC and Glidden DV and Vigneron DB and Barkovich AJ
DOI: 10.1212/wnl.58.4.542
PubMed: 11865130
02/2002

The Newborn Brain: Neuroscience and Clinical Applications
Archives of Pediatric Adolescence Medicine
2002

Seizure-associated brain injury in term newborns with perinatal asphyxia [3] (multiple letters)
Neurology
Campbell, C. and Wells, G. and Jacob, P. and Barkovich, A. and Miller, S.
DOI: 10.1212/WNL.59.7.1119
2002

Multiple risk factors in neonatal sinovenous thrombosis
Neurology
Wu, Y.W. and Miller, S.P. and Chin, K. and Collins, A.E. and Lomeli, S.C. and Chuang, N.A. and Barkovich, A.J. and Ferriero, D.M.
DOI: 10.1212/WNL.59.3.438
2002

Practice parameter: Neuroimaging of the neonate: Report of the quality standards subcommittee of the American academy of neurology and the practice committee of the child neurology society [1] (multiple letters)
Neurology
Miller, S. and Ferriero, D. and Barkovich, A.J. and Silverstein, F. and Ment, L.R. and Bada, H.S. and Barnes, P. and Grant, P.E. and Hirtz, D. and Papile, L.A. and Pinto-Martin, J. and Slovis, T.L.
DOI: 10.1212/WNL.59.10.1663
2002

Seizure-associated brain injury in term newborns with perinatal asphyxia
Neurology
Miller, S.P. and Weiss, J. and Barnwell, A. and Ferriero, D.M. and Latal-Hajnal, B. and Ferrer-Rogers, A. and Newton, N. and Partridge, J.C. and Glidden, D.V. and Vigneron, D.B. and Barkovich, A.J.
DOI: 10.1212/WNL.58.4.542
2002

Building Canada's health research capacity within the framework of the Canadian Institutes of Health Research.
Paediatrics & child health
Benzies KM and Barnes D and Clifford T and Bouayad A and Hardy D and Korneluk Y and Marrache AM and McCusker C and Miller S and Ring T and Walker M and Waterhouse C
DOI: 10.1093/pch/6.8.517
PubMed: 20084120
10/2001

Diagnostic profile of neonatal hypotonia: an 11-year study.
Pediatric neurology
Richer LP and Shevell MI and Miller SP
DOI: 10.1016/s0887-8994(01)00277-6
PubMed: 11483393
07/2001

Diagnostic profile of neonatal hypotonia: An 11-year study
Pediatric Neurology
Richer, L.P. and Shevell, M.I. and Miller, S.P.
DOI: 10.1016/S0887-8994(01)00277-6
2001

Neuromotor spectrum of periventricular leukomalacia in children born at term.
Pediatric neurology
Miller SP and Shevell MI and Patenaude Y and O'Gorman AM
DOI: 10.1016/s0887-8994(00)00172-7
PubMed: 11020641
08/2000

Recurrent artery of Heubner infarction in infancy.
Developmental medicine and child neurology
Miller SP and O'Gorman AM and Shevell MI
DOI: 10.1017/s0012162200000608
PubMed: 10855656
05/2000

Neuronal dysfunction in children with newly diagnosed temporal lobe epilepsy.
Pediatric neurology
Miller SP and Li LM and Cendes F and Caramanos Z and Rosenblatt B and Shevell MI and Andermann F and Arnold DL
DOI: 10.1016/s0887-8994(99)00159-9
PubMed: 10788744
04/2000

Septo-optic dysplasia plus: a spectrum of malformations of cortical development.
Neurology
Miller SP and Shevell MI and Patenaude Y and Poulin C and O'Gorman AM
DOI: 10.1212/wnl.54.8.1701
PubMed: 10762523
04/2000

Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy.
Neurology
Miller SP and Li LM and Cendes F and Tasch E and Andermann F and Dubeau F and Arnold DL
DOI: 10.1212/wnl.54.7.1465
PubMed: 10751259
04/2000

Treatment of acute disseminated encephalomyelitis with intravenous immunoglobulin.
Neurology
Sahlas DJ and Miller SP and Guerin M and Veilleux M and Francis G
DOI: 10.1212/wnl.54.6.1370
PubMed: 10746613
03/2000

Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy
Neurology
Miller, S.P. and Li, L.M. and Cendes, F. and Tasch, E. and Andermann, F. and Dubeau, F. and Arnold, D.L.
DOI: 10.1212/WNL.54.7.1465
2000

Recurrent artery of Heubner-infarction in infancy
Developmental Medicine and Child Neurology
Miller, S.P. and O{'}Gorman, A.M. and Shevell, M.I.
DOI: 10.1017/S0012162200000608
2000

Neuromotor spectrum of periventricular leukomalacia in children born at term
Pediatric Neurology
Miller, S.P. and Shevell, M.I. and Patenaude, Y. and O{'}Gorman, A.M.
DOI: 10.1016/S0887-8994(00)00172-7
2000

Neuronal dysfunction in children with newly diagnosed temporal lobe epilepsy
Pediatric Neurology
Miller, S.P. and Li, L.M. and Cendes, F. and Caramanos, Z. and Rosenblatt, B. and Shevell, M.I. and Andermann, F. and Arnold, D.L.
DOI: 10.1016/S0887-8994(99)00159-9
2000

Septo-optic dysplasia plus: A spectrum of malformations of cortical development
Neurology
Miller, S.P. and Shevell, M.I. and Patenaude, Y. and Poulin, C. and O{'}Gorman, A.M.
DOI: 10.1212/WNL.54.8.1701
2000

Neonatal neurologic prognostication: the asphyxiated term newborn.
Pediatric neurology
Shevell MI and Majnemer A and Miller SP
DOI: 10.1016/s0887-8994(99)00102-2
PubMed: 10593666
11/1999

Neonatal seizures: unusual causes.
Seminars in pediatric neurology
Miller SP and Shevell MI
DOI: 10.1016/s1071-9091(99)80002-3
PubMed: 10522328
09/1999

The neonatal presentation of Prader-Willi syndrome revisited.
The Journal of pediatrics
Miller SP and Riley P and Shevell MI
DOI: 10.1016/s0022-3476(99)70420-8
PubMed: 9931534
02/1999

Neonatal seizures: Unusual causes
Seminars in Pediatric Neurology
Miller, S.P. and Shevell, M.I. and Sheth, R.D.
DOI: 10.1016/S1071-9091(99)80002-3
1999

The neonatal presentation of Prader-Willi syndrome revisited
Journal of Pediatrics
Miller, S.P. and Riley, P. and Shevell, M.I.
DOI: 10.1016/S0022-3476(99)70420-8
1999

Neonatal neurologic prognostication: The asphyxiated term newborn
Pediatric Neurology
Shevell, M.I. and Majnemer, A. and Miller, S.P.
DOI: 10.1016/S0887-8994(99)00102-2
1999

Tuberous sclerosis complex and neonatal seizures.
Journal of child neurology
Miller SP and Tasch T and Sylvain M and Farmer JP and O'Gorman AM and Shevell MI
DOI: 10.1177/088307389801301205
PubMed: 9881532
12/1998

Spastic paraplegia, optic atrophy, microcephaly with normal intelligence, and XY sex reversal: a new autosomal recessive syndrome?
Journal of Medical Genetics
A S Teebi and S Miller and H Ostrer and P Eydoux and C Colomb-Brockmann and K Oudjhane and G Watters
DOI: 10.1136/jmg.35.9.759
09/1998

Infantile epileptic encephalopathy (Ohtahara syndrome) and migrational disorder.
Pediatric neurology
Miller SP and Dilenge ME and Meagher-Villemure K and O'Gorman AM and Shevell MI
DOI: 10.1016/s0887-8994(98)00009-5
PubMed: 9682886
07/1998

Congenital bilateral perisylvian polymicrogyria presenting as congenital hemiplegia.
Neurology
Miller SP and Shevell M and Rosenblatt B and Silver K and O'Gorman A and Andermann F
DOI: 10.1212/wnl.50.6.1866
PubMed: 9633745
06/1998

The diagnostic yield of the nerve–muscle skin biopsy in paediatric neurology practice
Pediatric Rehabilitation
S. Miller and M. Shevell and K. Silver and M. Kramer
DOI: 10.3109/17518429809068161
01/1998

Congenital bilateral perisylvian polymicrogyria presenting as congenital hemiplegia
Neurology
Miller, S.P. and Shevell, M. and Rosenblatt, B. and Silver, K. and O{'}Gorman, A. and Andermann, F.
DOI: 10.1212/WNL.50.6.1866
1998

Infantile epileptic encephalopathy (Ohtahara syndrome) and migrational disorder
Pediatric Neurology
Miller, S.P. and Dilenge, M.-E. and Meagher-Villemure, K. and O{'}Gorman, A.M. and Shevell, M.I.
DOI: 10.1016/S0887-8994(98)00009-5
1998

Aberrant Internal Carotid Artery Presenting in the Midline Retropharyngeal Space: Case Report
Canadian Association of Radiologists Journal
PubMed: 9030067
1997

Research

Current Projects
Advances in magnetic resonance (MR) technology allow for brain development and injury to be studied safely in critically ill newborns. MR imaging (MRI) is a sensitive tool to measure brain structure and injury. In particular, deformation morphometry, diffusion tensor imaging, and MR spectroscopic imaging, can be used to quantify brain structure, microstructure and metabolism. Using advanced magnetic resonance (MR) techniques, as well as bedside brain monitoring, such as amplitude integrated EEG and near infra-red spectroscopy, we study brain development and injury in vulnerable populations of newborns.

Abnormal brain development and injury in premature newborns

In 2003 in British Columbia, more than 5% of all newborns were born prematurely and/or at low birth weight. These children are at very high risk for developmental delays: 5-10% of low birth-weight children exhibit major motor deficits and 25-50% exhibit significant developmental and visual deficits. The most important brain pathology associated with these deficits is injury to the white matter. Our study is characterizing the consequences of abnormal brain development and white matter injury in the premature newborn, including how delayed brain development results in impaired motor and cognitive function. This study builds on our earlier observations that: 1) brain injury in premature newborns is safely detected with MRI before term-equivalent age; 2) focal non-cystic white matter injury is the characteristic pattern of injury in the premature newborn; 3) early brain injury is associated with adverse early neurodevelopmental outcome; and 4) brain injury in the immature brain impairs subsequent brain development.

Brain Injury in Newborns with Congenital Heart Disease

Developmental deficits in children with congenital heart disease are a serious problem and may be seen in more than one third of affected newborns. However, the reasons for these developmental deficits remain unknown and may occur prior to, during or following their cardiac surgery. In this study we are investigating the timing and severity of brain injury in newborns with congenital heart disease using advanced MR imaging techniques in utero, shortly before open-heart surgery and again soon after surgery. As newborns with congenital heart disease, like premature newborns, are also specifically vulnerable to white matter injury, studying these two populations allows us to explore shared mechanisms of white matter injury. Knowing the mechanisms and timing of brain injury in newborns with heart disease will be important for the rational design of studies to evaluate emerging strategies to protect the developing brain from injury.

Many physicians consider brain injury to be the major remaining challenge in caring for critically ill newborns. The ability of advanced MR brain imaging techniques to detect which newborns have abnormalities of the brain will help parents and physicians better care for these critically ill infants. The longer-term goal of my research program will be to test new strategies to prevent brain injury in the human newborn. The advanced MR techniques I am applying in this research program provide us with powerful surrogate markers of brain injury that will allow us to monitor the effect of novel strategies to protect the brain from injury.

Grants

CIHR Operating Grant – Project

"Analgesia and sedation in the preterm neonate

brain development and outcome" (2014-2020)

Honours & Awards

Tier 2 Canada Research Chair in Neonatal Neuroscience - 2010-2015

President Elect, Society for Pediatric Research 2012

Bloorview Children's Hospital Foundation Chair in Paediatric Neuroscience 2012

Research Group Members

Janet Rigney, Research Coordinator