Scientists had previously noted that the presence of a large protein called MondoA was associated with worse outcomes in several pediatric cancers, but they didn’t understand why.

​A recent discovery in Ewing sarcoma, an aggressive and often fatal childhood cancer, has uncovered the potential to prevent cancer cells from spreading beyond their primary tumour site. The breakthrough provides new insight into what triggers the process that allows cancer cells to survive while travelling throughout the body in the bloodstream.