- Overview
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I am a pediatric oncologist whose research focuses on improving outcomes for children with non-Hodgkin lymphoma and acute lymphoblastic leukemia. As a leader and a collaborator, I have been involved in the design, execution and publication studies focused on identifying opportunities and implementing interventions for decreasing the toxicities of oncology therapy including short- and long-term medical complications and the psychosocial difficulties and burdens of therapy. A specific area of focus continues to be understanding risks for serious infectious toxicities attributed to conventional chemotherapy and immunotherapy and strategies for prevention. Within the Children’s Oncology Group, I am the vice chair of the Acute Lymphoblastic Leukemia committee responsible for studies focused on toxicity and tolerability of therapy.
- Publications
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Hypogammaglobulinemia in Children Receiving Targeted Immunotherapies for B Lineage Malignancies: Practical Guidance for Assessment and Management
Pediatric Blood and Cancer
Long, A.H. and Aftandilian, C. and Barmettler, S. and Alexander, S.
DOI: 10.1002/pbc.31779
2025Reducing General Anesthesia for Lumbar Punctures in Pediatric Patients With Leukemia and Lymphoma, a Quality Improvement Project
Pediatric Blood and Cancer
Arane, K. and Li, D. and Baxter, T. and Gandhi, B. and Positano, K. and Howlett, M. and Everett, T. and Alexander, S.
DOI: 10.1002/pbc.31843
2025Prevention and Management of Infectious Complications in Pediatric Patients With Cancer: A Survey Assessment of Current Practices Across Children's Oncology Group Institutions
Pediatric Blood and Cancer
Slatnick, L.R. and Hoogstra, D. and Fisher, B.T. and Wolf, J. and Orgel, E. and Nessle, C.N. and Patel, P.A. and Miller, T.P. and Wilkes, J. and Dupuis, L.L. and Goode, E. and Jackson, K. and Willis, D.N. and Elgarten, C. and Aftandilian, C. and Thompson, J. and Alexander, S. and Beauchemin, M.P. and Belsky, J.A. and Hess, J. and Prudowsky, Z.D. and Guinipero, T. and Rossoff, J. and Demedis, J. and Walsh, A.M. and Richards, R. and Choi, D.K. and Dvorak, C.C. and Esbenshade, A.J.
DOI: 10.1002/pbc.31532
2025Multi-Institution Harmonization of Infection Care Pathways for Pediatric Oncology
Pediatric Blood and Cancer
Yan, A.P. and Mehrdadi, I. and Seelisch, J. and Robinson, P.D. and Punnett, A. and Patel, P. and Mark, C. and Koo, A. and Johnston, D.L. and Gibson, P. and Cox, S. and Alexander, S. and Aitcheson, M. and Tomlinson, D. and Dupuis, L.L. and Sung, L.
DOI: 10.1002/pbc.31824
2025Characterizing Difficulty and Life Disruption During B-Acute Lymphoblastic Leukemia Therapy From the Perspective of Parents: A Survey Study
Pediatric Blood and Cancer
Parker, K.N. and Alexander, S.W. and Jacola, L.M. and Buff, K.A. and Hwang, K. and Hashemi, E. and Stoddard, G.J. and Jibb, L.A.
DOI: 10.1002/pbc.32041
2025Current Treatment Strategies and Supportive Care Practices in the Care of Children and Adolescents With Mature B-Cell Non-Hodgkin Lymphoma: A Survey of Children's Oncology Group Institutions
Pediatric Blood and Cancer
Belsky, J.A. and Smith, C.M. and Alexander, S.
DOI: 10.1002/pbc.31687
2025Incidence and impact of prior history of serious infection in paediatric lymphoma: A population-based study
British Journal of Haematology
Bahabri, A.S. and Lau, C. and Kim, V.H.D. and Alexander, S. and Gupta, S.
DOI: 10.1111/bjh.70157
2025Clinical practice guideline- and care pathway-inconsistent care following implementation of adapted infection management care pathways
Supportive Care in Cancer
Mehrdadi, I. and Patel, P. and Robinson, P.D. and Mark, C. and Yan, A.P. and Alexander, S. and Aitcheson, M. and Cook, S. and Cox, S. and Gibson, P. and Johnston, D.L. and Koo, A. and Seelisch, J. and Tomlinson, D. and Dupuis, L.L. and Sung, L.
DOI: 10.1007/s00520-025-09693-2
2025Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children
New England Journal of Medicine
Gupta, S. and Rau, R.E. and Kairalla, J.A. and Rabin, K.R. and Wang, C. and Angiolillo, A.L. and Alexander, S. and Carroll, A.J. and Conway, S. and Gore, L. and Kirsch, I. and Kubaney, H.R. and Li, A.M. and McNeer, J.L. and Militano, O. and Miller, T.P. and Moyer, Y. and O?Brien, M.M. and Okada, M. and Reshmi, S.C. and Shago, M. and Wagner, E. and Winick, N. and Wood, B.L. and Haworth?Wright, T. and Zaman, F. and Zugmaier, G. and Zupanec, S. and Devidas, M. and Hunger, S.P. and Teachey, D.T. and Raetz, E.A. and Loh, M.L.
DOI: 10.1056/NEJMoa2411680
2025Baseline Characteristics of Parents Enrolled in Children's Oncology Group Study ACCL20N1CD: Financial Toxicity During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States
Pediatric Blood and Cancer
Santacroce, S.J. and Beauchemin, M.P. and Ponce, O. and Ji, L. and Ramakrishnan, S. and Bona, K. and Mu{\~n}eton-Casta{\~n}o, Y. and Robles, J.M. and Vargas, S. and De Los Santos, C. and Fisher, B. and Alexander, S. and Sung, L. and Parsons, S.K.
DOI: 10.1002/pbc.31710
2025Attitudes Toward COVID-19 Vaccination Among Pediatric Acute Lymphoblastic Leukemia Patients and Their Caregivers
Pediatric Blood and Cancer
Shapiro, J.R. and Shapiro, G.K. and Gupta, S. and Alexander, S. and Science, M. and Watts, T.H. and Bolotin, S.
DOI: 10.1002/pbc.31696
2025Detection of OXA-181 Carbapenemase in Shigella flexneri
Emerging Infectious Diseases
Dhabaan, G. and Jamal, H. and Ouellette, D. and Alexander, S. and Arane, K. and Campigotto, A. and Tadros, M. and Pich{\'e}-Renaud, P.-P.
DOI: 10.3201/eid3005.231558
2024Healthcare professional perspectives following implementation of an infection management care pathway for pediatric patients with cancer: a qualitative study
Supportive Care in Cancer
Mark, C. and Yan, A.P. and Robinson, P.D. and Alexander, S. and Aitcheson, M. and Cox, S. and Gibson, P. and Johnston, D.L. and Koo, A. and Seelisch, J. and Tomlinson, D. and Dupuis, L.L. and Sung, L.
DOI: 10.1007/s00520-024-08612-1
2024Health Supervision for Children and Adolescents With Sickle Cell Disease: Clinical Report
Pediatrics
Yates, A.M. and Aygun, B. and Nuss, R. and Rogers, Z.R. and Wetmore, C. and Dickens, D. and Majumdar, S. and Rogers, Z.R. and Stoffman, J. and Warwick, A. and Sheikh, I. and Mendonca, E.A. and Michel, J.J. and Kirkwood, S. and Graham, D. and Hastings, C. and DiPaola, J. and Hord, J. and Alexander, S. and Huh, W. and Jeng, M. and Velez, M. and Wechsler, D. and Hooker, R.
DOI: 10.1542/peds.2024-066842
2024Editorial: Non-cellular immunotherapies in pediatric malignancies
Frontiers in Immunology
Alexander, S. and Harker-Murray, P. and Hayashi, R.J.
DOI: 10.3389/fimmu.2024.1379278
2024Patient-Specific Blister Packaging of Medications in the Oncology Camp Setting: Optimizing Medication Safety and Dispensing Processes
Journal of Pediatric Hematology Oncology Nursing
Ross, S. and Drynan-Arsenault, J. and Peirce, M. and Williams, M. and Alexander, S.
DOI: 10.1177/27527530241282427
2024Impact of Propofol Exposure on Neurocognitive Outcomes in Children with High-Risk B ALL: A Children's Oncology Group Study
Journal of Clinical Oncology
Alexander, S. and Kairalla, J.A. and Gupta, S. and Hibbitts, E. and Weisman, H. and Anghelescu, D. and Winick, N.J. and Krull, K.R. and Salzer, W.L. and Burke, M.J. and Gore, L. and Devidas, M. and Embry, L. and Raetz, E.A. and Hunger, S.P. and Loh, M.L. and Hardy, K.K.
DOI: 10.1200/JCO.23.01989
2024Reply to C.T. Matava et al
Journal of Clinical Oncology
Alexander, S. and Kairalla, J.A. and Gupta, S. and Hibbitts, E. and Weisman, H. and Anghelescu, D. and Winick, N.J. and Krull, K.R. and Salzer, W.L. and Burke, M.J. and Gore, L. and Devidas, M. and Embry, L. and Raetz, E.A. and Hunger, S.P. and Loh, M.L. and Hardy, K.K.
DOI: 10.1200/JCO-24-01244
2024Inclusion of a core patient-reported outcomes battery in adolescent and young adult cancer clinical trials
Journal of the National Cancer Institute
Roth, M.E. and Parsons, S.K. and Ganz, P.A. and Wagner, L.I. and Hinds, P.S. and Alexander, S. and Bingen, K. and Bober, S.L. and Brackett, J. and Cella, D. and Henry, N.L. and Indelicato, D.J. and Johnson, R.H. and Miller, T.P. and Rosenberg, S.M. and Schmitz, K.H. and Thanarajasingam, G. and Reeve, B.B. and Salsman, J.M.
DOI: 10.1093/jnci/djac166
2023Guideline for the Management of Fever and Neutropenia in Pediatric Patients with Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update
Journal of Clinical Oncology
Lehrnbecher, T. and Robinson, P.D. and Ammann, R.A. and Fisher, B. and Patel, P. and Phillips, R. and Beauchemin, M.P. and Carlesse, F. and Castagnola, E. and Davis, B.L. and Elgarten, C.W. and Groll, A.H. and Haeusler, G.M. and Koenig, C. and Santolaya, M.E. and Tissing, W.J.E. and Wolf, J. and Alexander, S. and Hu, H. and Dupuis, L.L. and Sung, L.
DOI: 10.1200/JCO.22.02224
2023“It just made me feel better”: qualitative examination of the implementation of a novel virtual psychosocial support program for adolescents with cancer
Supportive Care in Cancer
Kilfoy, A. and Panesar, P. and Hashemi, E. and Masama, T. and Pereira, M. and Liu, W. and Alexander, S. and Korenblum, C. and Jibb, L.A.
DOI: 10.1007/s00520-023-08054-1
2023Effect of rituximab on immune status in children with mature B-cell non-Hodgkin lymphoma: a prespecified secondary analysis of the Inter-B-NHL Ritux 2010 trial
Lancet Haematology
Alexander, S. and Aup{\'e}rin, A. and Bomken, S. and Cs{\'o}ka, M. and Kazanowska, B. and Chiang, A.K. and Andres, M. and Uyttebroeck, A. and Burke, G.A.A. and Zsiros, J. and Pillon, M. and Bollard, C.M. and Mussolin, L. and Verdu-Amoros, J. and Neven, B. and Barkauskas, D.A. and Wheatley, K. and Patte, C. and Gross, T.G. and Minard-Colin, V.
DOI: 10.1016/S2352-3026(23)00062-5
2023Development of a centralised triage centre for children with cancer and blood disorders in response to the humanitarian crisis in Ukraine
Lancet Oncology
Salek, M. and Mueller, A. and Alanbousi, I. and Cepowska, Z. and Dutkiewicz, M. and Earl, J. and Evseev, D. and Kizyma, R. and Kliuchkivska, K. and Kolodrubiec, J. and Matczak, K. and Nogovitsyna, Y. and Oszer, A. and Pogorelyy, M. and Raciborska, A. and Rasul, S. and Sokolowski, I. and Sopilnyak, A. and Vinitsky, A. and Wlodarski, M.W. and Wobst, N. and Yakimkova, T. and Rodriguez-Galindo, C. and Wise, P.H. and Mlynarski, W. and Agulnik, A. and Alexander, S.W. and Apel, A. and Adyrov, M.V. and Avula, M. and Bal, W.A. and Balwierz, W.A. and Basset-Salom, L. and Bastardo Blanco, D. and Bauer, K.J. and Bayazitov, I.T. and Berlanga, P. and Bhakta, N.H. and Bieniek, K.A. and Bien, E.I. and Blackwood, C.A. and Blair, S.J. and Bodak, K.I. and Bordeianu, I. and Bouffet, E. and Braganca, J.M. and Bucurenci, M.S. and Budny, E.B. and Budzyn, A. and Bumgardner, C.C. and Burditt, R.N. and Burnside Clapp, V. and Bykov, V.V. and Ca{\~n}ete, A. and Carnelli, M. and Cela, E. and Chaber, R. and Cherner-Drieux, A. and Chubata, M. and Clough, H.M. and Czauderna, P.S. and Czernicka - Siwecka, J. and Czyzewski, K. and Dalle, J.-H. and Dashchakovska, O. and de Koning, L.A. and Dembowska-Baginska, B.M. and Derwich, K. and Dirksen, U. and Dommett, R. and Dorosh, O.I. and dos Reis Farinha, N.J. and Drabko, K.A. and Dragomir, M.D. and Dworzak, M. and Dyma, S.V. and Eggert, A. and English, M.W. and Farren, B.S. and Fedyk, N.Y. and Fern{\'a}ndez-Teijeiro, A. and Ferneza, S.R. and Foster, W.B. and Fox Irwin, L.E. and Ga??zkowski, R.M. and Ganieva, G. and Garanzha, V.A. and Gelman, M.S. and Godzinski, J.K. and Goeres, A.F. and Golban, R. and Graetz, D.E. and Greiner, J. and Griksaitis, M.J. and Gupta, S. and Hampel, M.A. and Hastings, S.G. and Heenen, D.L. and Hill, M.C. and Holiuk, I. and Holter, W. and Hough, R.E. and Hutnik, L.M. and Irga-Jaworska, N. and Istomin, O.A. and Ignatova, A. and Janczar, S.L. and Kacharian, A. and Kalwak, K. and Karolczyk, G.M. and Karpenko, N.M. and Katsubo, H.O. and Kattamis, A. and Kazanowska, B.J. and Kentsis, A. and Ketteler, P. and Kienesberger, A. and Kiselev, R. and Kizyma, Z.P. and Klymniuk, H.I. and Kolenova, A. and Kostiuk, Y. and Kowalik, T. and Kozlova, O.I. and Kozubenko, V. and Kraal, K. and Kramar, T.O. and Krawczuk-Rybak, M.M. and Kulemzina, I. and Kurkowska, P. and Kuzyk, A.S. and Ladenstein, R.L. and Laguna, P.J. and Lassaletta, A. and Lehmberg, K. and Leontieva, O. and Liashenko, S. and Loizou, L.G. and Lucchetta, S.A. and Lupo, M.W. and Lysytsia, L. and Lysytsia, O. and Machnik, K.A. and Massimino, M. and Mainland, J.A. and Matysiak, M.J. and Mayeur, P. and Miller, B.A. and Minervina, A.A. and Mishkova, V. and Mizia-Malarz, A.J. and Morales La Madrid, A. and Moreira, D.C. and Moreno, L. and Moskvin, V.P. and Mukkada, S.T. and Muszy?ska-Ros?an, K.M. and Mykychak, I.V. and Niemeyer, C. and Nelson, A.J. and Ociepa, T. and Oltolini, S. and Onipko, N. and Pappas, A. and Patel, A.B. and Patrahau, A.A. and Pauley, J.L. and Pavlenko, Y.M. and Pavlovych, A.O. and Peregud-Pogorzelski, J.W. and Perek-Polnik, M. and P{\'e}rez, V. and P{\'e}rez-Mart{\'i}nez, A. and Pikman, Y. and Pitozzi, G.P. and Portugal, R.G. and Posternak, V.V. and Pleshkan, V. and Prete, A. and Pritchard-Jones, K. and Radaelli, A. and Reeves, T.J. and Reinhardt, D. and Reshetnyak, A.V. and Rider, A.J. and Rizzari, C. and Rizzi, D.D. and Rodriguez Hermosillo, K.G. and Ronenko, O.V. and Rostkowska, A.O. and Rudko, L.Y. and Sakaan, F.M. and Sakhar, N.A. and Salman, Z.S. and Savva, N.N. and Scaccaglia, D. and Schaeffer, E.H. and Schneider, C.U. and Scobie, N. and Semeniuk, O.V. and Shevchyk, R. and Shuler, A. and Shvets, S. and Sniderman, L. and Skoczen, S.P. and Smeal, W.J. and Sonkin, A.A. and Spota, A. and Sramkova, L. and Stepanjuk, A.I. and Sterba, J. and Strahm, B. and Styczynski, J. and Svintsova, O. and Synyuta, A.V. and Szczepanski, T. and Szczucinski, P.K. and Szmyd, B.M. and Tasso Cereceda, M. and Teliuk, A. and Tomanek, I. and Topping, P. and Torrent, M. and Treli?ska, J. and Troyanovska, O.O. and Tsurkan, L.G. and Tsymbalyuk-Voloshyn, I. and Tyupa, S.I. and Urasinski, T.F. and Urbanek D?dela, A. and Vasilieva, N.J. and Vasilyeva, A. and Verd{\'u}-Amor{\'o}s, J. and Vilcu-Bajurean, N. and Vinitsky, L. and Vivtcharenko, V. and Vovk, N. and Volpe, G. and Vorobel, O.I. and Wachowiak, J.T. and Wasiak, M.S. and Wiedower, L.A. and Wuenschel, L.I. and Wysocki, M.S. and Yurieva, M. and Zagurska, A. and Zakharenko, S.S. and Zakharenko, A.V. and Zapotochna, K. and Zawitkowska, J.E. and Zecca, M.
DOI: 10.1016/S1470-2045(23)00456-4
2023Crizotinib in Combination with Chemotherapy for Pediatric Patients with ALK+ Anaplastic Large-Cell Lymphoma: The Results of Children's Oncology Group Trial ANHL12P1
Journal of Clinical Oncology
Lowe, E.J. and Reilly, A.F. and Lim, M.S. and Gross, T.G. and Saguilig, L. and Barkauskas, D.A. and Wu, R. and Alexander, S. and Bollard, C.M.
DOI: 10.1200/JCO.22.00272
2023Outcomes of Coronavirus Disease 2019 Infection in Children and Adolescents With Cancer in Canada: Population-based Study and Systematic Review
Journal of Pediatric Hematology Oncology
Mark, C. and Gibson, P. and Lafay-Cousin, L. and Martin, G. and Oberoi, S. and Pecheux, L. and Rassekh, S.R. and Zorzi, A. and Alexander, S. and Gupta, S.
DOI: 10.1097/MPH.0000000000002644
2023“It Just Made Me Feel Better": Qualitative Examination of the Implementation of a Novel Virtual Psychosocial Support Program for Adolescents with Cancer
Research Square
Kilfoy, A. and Panesar, P. and Hashemi, E. and Masama, T. and Pereira, M. and Liu, W. and Alexander, S. and Korenblum, C. and Jibb, L.
DOI: 10.21203/rs.3.rs-3073663/v1
2023Severe hypoglycaemia in paediatric oncology: characterisation and risk factors
BMJ Supportive and Palliative Care
Joseph-Frederick, Z. and Keis, J. and Green, G. and Petrazzini, A. and Alexander, S. and Kovacevic, A. and Oei, K. and Sung, L.
DOI: 10.1136/spcare-2023-004526
2023Prevalence and Risk Factors for Moral Distress in Pediatric Oncology Health Care Professionals
JCO Oncology Practice
Mathews, N. and Alodan, K. and Kuehne, N. and Widger, K. and Locke, M. and Fung, K. and Gandhi, S. and McLean, J. and Hossain, A. and Alexander, S.
DOI: 10.1200/OP.23.00059
2023Children's Oncology Group's 2023 blueprint for research: Non-Hodgkin lymphoma
Pediatric Blood and Cancer
El-Mallawany, N.K. and Alexander, S. and Fluchel, M. and Hayashi, R.J. and Lowe, E.J. and Giulino-Roth, L. and Wistinghausen, B. and Hermiston, M. and Allen, C.E.
DOI: 10.1002/pbc.30565
2023Prospective Evaluation of the Fungitell® (1¿3) Beta-D-Glucan Assay as a Diagnostic Tool for Invasive Fungal Disease in Pediatric Allogeneic Hematopoietic Cell Transplantation: A Report from the Children's Oncology Group
Pediatric Transplantation
Otto, W.R. and Dvorak, C.C. and Boge, C.L.K. and Ostrosky-Zeichner, L. and Esbenshade, A.J. and Nieder, M.L. and Alexander, S. and Steinbach, W.J. and Dang, H. and Villaluna, D. and Chen, L. and Skeens, M. and Zaoutis, T.E. and Sung, L. and Fisher, B.T.
DOI: 10.1111/petr.14399
2023Cervical lymph node biopsies in the evaluation of children with suspected lymphoproliferative disorders: Experience in a tertiary pediatric setting
Journal of Pediatric Surgery
Sgro, J.M. and Campisi, E.S. and Selvam, S. and Greer, M.-L.C. and Alexander, S. and Ngan, B. and Campisi, P.
DOI: 10.1016/j.jpedsurg.2021.08.024
2022Risk of COVID-19 Infections and of Severe Complications Among Survivors of Childhood, Adolescent, and Young Adult Cancer: A Population-Based Study in Ontario, Canada
Journal of Clinical Oncology
Gupta, S. and Sutradhar, R. and Alexander, S. and Science, M. and Lau, C. and Nagamuthu, C. and Agha, M. and Nathan, P.C. and Hodgson, D.
DOI: 10.1200/JCO.21.02592
2022Traumatic stress symptoms in family caregivers of patients with acute leukaemia: protocol for a multisite mixed methods, longitudinal, observational study
BMJ Open
Jibb, L.A. and Nanos, S.M. and Alexander, S. and Malfitano, C. and Rydall, A. and Gupta, S. and Schimmer, A.D. and Zimmermann, C. and Hales, S. and Nissim, R. and Marmar, C. and Schultebraucks, K. and Mah, K. and Rodin, G.
DOI: 10.1136/bmjopen-2022-065422
2022Superior outcomes with paediatric protocols in adolescents and young adults with aggressive B-cell non-Hodgkin lymphoma
British Journal of Haematology
Gupta, S. and Alexander, S. and Pole, J.D. and Sutradhar, R. and Crump, M. and Nagamuthu, C. and Baxter, N.N. and Nathan, P.C.
DOI: 10.1111/bjh.17862
2022Pilot randomized psychosocial trial of a screening intervention in pediatric oncology
Psycho Oncology
Barrera, M. and Desjardins, L. and Prasad, S. and Shama, W. and Alexander, S. and Szatmari, P. and Hancock, K.
DOI: 10.1002/pon.5857
2022Global effort to evacuate Ukrainian children with cancer and blood disorders who have been affected by war
Lancet Haematology
Agulnik, A. and Kizyma, R. and Salek, M. and Wlodarski, M.W. and Pogorelyy, M. and Oszer, A. and Yakimkova, T. and Nogovitsyna, Y. and Dutkiewicz, M. and Dalle, J.-H. and Dirksen, U. and Eggert, A. and Fern{\'a}ndez-Teijeiro, A. and Greiner, J. and Kraal, K. and Mueller, A. and Sramkova, L. and Zecca, M. and Wise, P.H. and Mlynarski, W. and Avula, M. and Adyrov, M.V. and Berlanga, P. and Blackwood, C.A. and Bouffet, E. and Czauderna, P.S. and de Koning, L.A. and dos Reis Farinha, N.J. and Foster, W.B. and Graetz, D.E. and Gupta, S. and Holter, W. and Hough, R.E. and Kliuchkivska, K. and Kolenova, A. and Ko?odrubiec, J. and Moreira, D.C. and Mukkada, S.T. and Mykychak, I. and Raciborska, A. and Salman, Z.S. and Sopilnyak, A. and Tyupa, S. and Vinitsky, A. and Wobst, N.M. and Miller, B.A. and Rasul, S.S. and Rodriguez-Galindo, C. and Alanbousi, I. and Alexander, S.W. and Apel, A. and Bal, W.A. and Balwierz, W.A. and Basset-Salom, L. and Bastardo Blanco, D. and Bauer, K.J. and Bayazitov, I.T. and Bhakta, N.H. and Bien, E.I. and Bieniek, K.A. and Blair, S.J. and Bodak, K.I. and Bordeianu, I.M. and Braganca, J.M. and Bucurenci, M.S. and Budny, E.B. and Budzyn, A. and Bumgardner, C.C. and Burditt, R.N. and Burnside Clapp, V.G. and Bykov, V. and Ca{\~n}ete, A. and Carnelli, M. and Cela, E. and Cepowska, Z.P. and Chaber, R. and Cherner-Drieux, A. and Chubata, M. and Clough, H.M. and Czernicka - Siwecka, J. and Czyzewski, K. and Dashchakovska, O. and Dembowska-Baginska, B.M. and Derwich, K. and Dommett, R. and Dorosh, O. and Drabko, K.A. and Dragomir, M.D. and Dworzak, M. and Dyma, S. and Earl, J.D. and English, M.W. and Evseev, D.A. and Farren, B.S. and Fedyk, N. and Ferneza, S. and Fox Irwin, L.E. and Ga??zkowski, R.M. and Ganieva, G. and Garanzha, V. and Gelman, M.S. and Godzinski, J.K. and Goeres, A.F. and Golban, R. and Griksaitis, M.J. and Hampel, M.A. and Hastings, S.G. and Heenen, D.L. and Hill, M.C. and Holiuk, I. and Hutnik, L.M. and Irga-Jaworska, N. and Istomin, O. and Janczar, S.L. and Kacharian, A. and Kalwak, K. and Karolczyk, G.M. and Karpenko, N.M. and Katsubo, H. and Kaznowska, B.J. and Kentsis, A. and Ketteler, P. and Kienesberger, A. and Kiselev, R. and Kizyma, Z. and Klymniuk, H. and Kostiuk, Y. and Kowalik, T. and Kozlova, O. and Kozubenko, V. and Kramar, T. and Krawczuk-Rybak, M. and Kulemzina, I. and Kurkowska, P. and Kuzyk, A.S. and Ladenstein, R.L. and Laguna, P.J. and Lassaletta, A. and Lehmberg, K. and Leontieva, O. and Liashenko, S. and Loizou, L.G. and Lucchetta, S.A. and Lupo, M.W. and Lysytsia, L. and Lysytsia, O. and Machnik, K.A. and Mainland, J.A. and Matczak, K.E. and Matysiak, M.J. and Mayeur, P. and Minervina, A.A. and Mishkova, V. and Mizia-Malarz, A.J. and Morales La Madrid, A. and Moreno, L. and Moskvin, V.P. and Muszy?ska-Ros?an, K.M. and Nelson, A.J. and Ociepa, T. and Oltolini, S. and Onipko, N. and Pappas, A. and Patel, A.B. and Patrahau, A. and Pauley, J.L. and Pavlenko, Y. and Pavlovych, A. and Peregud-Pogorzelski, J. and Perek-Polnik, M. and Perez, V. and Perez-Martinez, A. and Pikman, Y. and Pitozzi, G. and Portugal, R.G. and Posternak, V.V. and Prete, A. and Pritchard-Jones, K. and Radaelli, A. and Reeves, T. and Reinhardt, D. and Reshetnyak, A.V. and Rider, A.J. and Rizzari, C. and Rizzi, D. and Rodriguez Hermosillo, K.G. and Ronenko, O. and Rostowska, A.O. and Rudko, L. and Sakaan, F.M. and Sakhar, N. and Savva, N.N. and Scaccaglia, D. and Schaeffer, E.H. and Schneider, C.U. and Scobie, N. and Semeniuk, O. and Shevchyk, R. and Shuler, A.I. and Shvets, S. and Skoczen, S.P. and Smeal, W.J. and Sokolowski, I. and Sonkin, A.A. and Stepanjuk, A.I. and Spota, A. and Sterba, J. and Styczynski, J. and Svintsova, O. and Synyuta, A.V. and Szczepanski, T. and Szczucinski, P.K. and Szmyd, B.M. and Tasso Cereceda, M. and Teliuk, A. and Tomanek, I. and Topping, P. and Torrent, M. and Treli?ska, J. and Troyanovska, O. and Trubnikova, E. and Tsurkan, L.G. and Tsymbalyuk-Voloshyn, I. and Urasinski, T.F. and Urbanek-Dadela, A. and Vasilieva, N. and Vasilyeva, A. and Verd{\'u}-Amor{\'o}s, J. and Vilcu-Bajurean, N. and Vinitsky, L. and Volpe, G. and Vorobel, O. and Wachowiak, J.T. and Wasiak, M.S. and Wiedower, L.A. and Wuenschel, L.I. and Wysocki, M.S. and Yurieva, M. and Zagurska, A. and Zakharenko, S.S. and Zakharenko, A.V. and Zapotochna, K. and Zawitkowska, J.E.
DOI: 10.1016/S2352-3026(22)00259-9
2022Answers to common questions about COVID-19 vaccines in children with cancer
Pediatric Blood and Cancer
Caniza, M.A. and Homsi, M.R. and Bate, J. and Adrizain, R. and Ahmed, T. and Alexander, S. and Bhattacharyya, A. and Copado-Gutierrez, J.L. and Gutierrez, I. and Lim, Y.Y. and Morrissey, L. and Naidu, G. and Paintsil, V. and Radhakrishnan, N. and Mukkada, S. and Phillips, R. and Alexander, K.A. and Pritchard-Jones, K.
DOI: 10.1002/pbc.29985
2022A qualitative examination of the benefits and challenges of a psychosocial screening intervention in pediatric oncology: “Support comes to us”
Pediatric Blood and Cancer
Hancock, K. and Barrera, M. and Prasad, S. and Desjardins, L. and Shama, W. and Alexander, S. and Szatmari, P.
DOI: 10.1002/pbc.29578
2022Reply to R. Lakhotia et al
Journal of Clinical Oncology
Burke, G.A.A. and Minard-Colin, V. and Aup{\'e}rin, A. and Alexander, S. and Pillon, M. and Delgado, R. and Zs{\'i}ros, J. and Uyttebroeck, A. and Dartigues, P. and Miles, R.R. and Kazanowska, B. and Chiang, A.K. and Haouy, S. and Bollard, C.M. and Csoka, M. and Wheatley, K. and Barkauskas, D.A. and Adamson, P.C. and Vassal, G. and Patte, C. and Gross, T.G.
DOI: 10.1200/JCO.21.02912
2022Rationale and design of Children’s Oncology Group (COG) study ACCL20N1CD: financial distress during treatment of acute lymphoblastic leukemia in the United States
BMC Health Services Research
Beauchemin, M. and Santacroce, S.J. and Bona, K. and Dang, H. and Alexander, S. and Allen, K. and De Los Santos, C. and Fisher, B. and Mu{\~n}eton-Casta{\~n}o, Y. and Ponce, O. and Vargas, S. and Sugalski, A. and Sung, L. and Parsons, S.
DOI: 10.1186/s12913-022-08201-0
2022Perceptions of parents of pediatric patients with acute lymphoblastic leukemia on oral chemotherapy administration: A qualitative analysis
Pediatric Blood and Cancer
Tang, N. and Kovacevic, A. and Zupanec, S. and Sivananthan, A. and Patel, R. and Patel, P. and Vennettilli, A. and Paw Cho Sing, E. and Alexander, S. and Sung, L. and Dupuis, L.L.
DOI: 10.1002/pbc.29329
2022Improving infectious adverse event reporting for children and adolescents enrolled in clinical trials for acute lymphoblastic leukemia: A report from the Children's Oncology Group
Pediatric Blood and Cancer
Elgarten, C.W. and Thompson, J.C. and Angiolillo, A. and Chen, Z. and Conway, S. and Devidas, M. and Gupta, S. and Kairalla, J.A. and McNeer, J.L. and O{'}Brien, M.M. and Rabin, K.R. and Rau, R.E. and Rheingold, S.R. and Wang, C. and Wood, C. and Raetz, E.A. and Loh, M.L. and Alexander, S. and Miller, T.P.
DOI: 10.1002/pbc.29937
2022Safety of administration of BNT162b2 mRNA (Pfizer-BioNTech) COVID-19 vaccine in youths and young adults with a history of acute lymphoblastic leukemia and allergy to PEG-asparaginase
Pediatric Blood & Cancer
Catherine Mark and Sumit Gupta and Angela Punnett and Julia Upton and Julia Orkin and Adelle Atkinson and Lindsay Clarke and Alice Heisey and Christine McGovern and Sarah Alexander
DOI: 10.1002/pbc.29295
11/2021Central nervous system relapse in a child with anaplastic large cell lymphoma: potential for new therapeutic strategies
Cancer Reports
Enass H. Raffa and Helen M. Branson and Bo Ngan and Sarah Alexander and Oussama Abla
DOI: 10.1002/cnr2.1377
10/2021Musculoskeletal impairments in children receiving intensive therapy for acute leukemia or undergoing hematopoietic stem cell transplant: A report from the Children's Oncology Group
Pediatric Blood & Cancer
Joel Thompson and Brian Fisher and Lillian Sung and Christopher Dvorak and Ha Dang and Tammy Lo and Sarah Alexander
DOI: 10.1002/pbc.29053
08/2021Feasibility of ultrasound-assisted lumbar punctures performed by pediatric oncologists at the point of care
Pediatric Blood & Cancer
Furqan Shaikh and Cristian Arzola and Sarah Alexander and Jose C. A. Carvalho and Tobias Everett and Manohar Shroff and Andrea S. Doria and Luc Trottier and Teresa To and Lillian Sung
DOI: 10.1002/pbc.29015
07/2021Brentuximab vedotin in combination with chemotherapy for pediatric patients with ALK+ ALCL: results of COG trial ANHL12P1
Blood
Eric J. Lowe and Anne F. Reilly and Megan S. Lim and Thomas G. Gross and Lauren Saguilig and Donald A. Barkauskas and Rui Wu and Sarah Alexander and Catherine M. Bollard
DOI: 10.1182/blood.2020009806
07/2021Protocol for mapping psychosocial screening to resources in pediatric oncology: a pilot randomized controlled trial
Pilot and Feasibility Studies
Desjardins, L. and Hancock, K. and Szatmari, P. and Alexander, S. and Shama, W. and De Souza, C. and Mills, D. and Abla, O. and Barrera, M.
DOI: 10.1186/s40814-021-00878-0
2021Prospective Evaluation of Galactomannan and (1¿3) ß-d-Glucan Assays as Diagnostic Tools for Invasive Fungal Disease in Children, Adolescents, and Young Adults with Acute Myeloid Leukemia Receiving Fungal Prophylaxis
Journal of the Pediatric Infectious Diseases Society
Fisher, B.T. and Westling, T. and Boge, C.L.K. and Zaoutis, T.E. and Dvorak, C.C. and Nieder, M. and Zerr, D.M. and Wingard, J.R. and Villaluna, D. and Esbenshade, A.J. and Alexander, S. and Gunn, S. and Wheat, L.J. and Sung, L.
DOI: 10.1093/jpids/piab036
2021A Randomized Trial of Caspofungin vs Triazoles Prophylaxis for Invasive Fungal Disease in Pediatric Allogeneic Hematopoietic Cell Transplant
Journal of the Pediatric Infectious Diseases Society
Dvorak, C.C. and Fisher, B.T. and Esbenshade, A.J. and Nieder, M.L. and Alexander, S. and Steinbach, W.J. and Dang, H. and Villaluna, D. and Chen, L. and Skeens, M. and Zaoutis, T.E. and Sung, L.
DOI: 10.1093/jpids/piaa119
2021Dose-Adjusted Etoposide, Doxorubicin, and Cyclophosphamide With Vincristine and Prednisone Plus Rituximab Therapy in Children and Adolescents With Primary Mediastinal B-Cell Lymphoma: A Multicenter Phase II Trial
Journal of Clinical Oncology
Amos Burke, G.A. and Minard-Colin, V. and Aup{\'e}rin, A. and Alexander, S. and Pillon, M. and Delgado, R. and Zs{\'i}ros, J. and Uyttebroeck, A. and Dartigues, P. and Miles, R.R. and Kazanowska, B. and Chiang, A.K. and Haouy, S. and Bollard, C.M. and Csoka, M. and Wheatley, K. and Barkauskas, D.A. and Adamson, P.C. and Vassal, G. and Patte, C. and Gross, T.G.
DOI: 10.1200/JCO.21.00920
2021Conventional compared to network meta-analysis to evaluate antibiotic prophylaxis in patients with cancer and haematopoietic stem cell transplantation recipients
BMJ Evidence Based Medicine
Martinez, J.P.D. and Robinson, P.D. and Phillips, B. and Lehrnbecher, T. and Koenig, C. and Fisher, B. and Egan, G. and Dupuis, L.L. and Ammann, R.A. and Alexander, S. and Cabral, S. and Tomlinson, G. and Sung, L.
DOI: 10.1136/bmjebm-2020-111362
2021Diagnostic discrepancies between antemortem clinical diagnosis and autopsy findings in pediatric cancer patients
Virchows Archiv
Raghuram, N. and Alodan, K. and Bartels, U. and Alexander, S. and Pole, J.D. and Gibson, P. and Johnston, D.L. and Portwine, C. and Silva, M. and Sung, L.
DOI: 10.1007/s00428-020-03002-4
2021Virtual support groups in pediatric hematology/oncology during COVID-19: Lessons learned from the SickKids experience
Pediatric Blood and Cancer
Kaka, A. and Shama, W. and Lucchetta, S. and Nishimura, C. and Cottingham, D. and Positano, K. and Markowitz, S. and Fung, K. and Yohan, A. and Horan, R. and Chin, M. and Jensen, P. and Chisholm, L. and Alexander, S. and Korenblum, C.
DOI: 10.1002/pbc.29378
2021Levofloxacin prophylaxis in hospitalized children with leukemia: A cost-utility analysis
Pediatric Blood & Cancer
Brandon Maser and Marie-Claude Pelland-Marcotte and Sarah Alexander and Lillian Sung and Sumit Gupta
DOI: 10.1002/pbc.28643
10/2020Outcomes of children with chronic myeloid leukemia: A population-based cohort study
Pediatric Blood & Cancer
Grace Egan and Uma Athale and Donna Johnston and Jason D. Pole and Mariana Silva and Alexandra Zorzi and Sarah Alexander
DOI: 10.1002/pbc.28491
09/2020Recommendations for medical care in the pediatric oncology camp setting: Consensus statements based on Delphi methodology
Pediatric Blood & Cancer
Sarah Alexander and Michelle Science and Vicky Breakey and Averill Clarke and Paul Gibson
DOI: 10.1002/pbc.28107
03/2020Quality of life in pediatric oncology patients, caregivers and siblings after psychosocial screening: a randomized controlled trial
Supportive Care in Cancer
Barrera, M. and Hancock, K. and Atenafu, E. and Alexander, S. and Solomon, A. and Desjardins, L. and Shama, W. and Chung, J. and Mills, D.
DOI: 10.1007/s00520-019-05160-x
2020Psychosocial screening and mental health in pediatric cancer: A randomized controlled trial.
Health Psychology
Barrera, M. and Alexander, S. and Atenafu, E.G. and Chung, J. and Hancock, K. and Solomon, A. and Desjardins, L. and Shama, W. and Mills, D.
DOI: 10.1037/hea0000825
2020Rituximab for high-risk, mature B-cell non-Hodgkin’s lymphoma in children
New England Journal of Medicine
Minard-Colin, V. and Aup{\'e}rin, A. and Pillon, M. and Burke, G.A.A. and Barkauskas, D.A. and Wheatley, K. and Delgado, R.F. and Alexander, S. and Uyttebroeck, A. and Bollard, C.M. and Zsiros, J. and Csoka, M. and Kazanowska, B. and Chiang, A.K. and Miles, R.R. and Wotherspoon, A. and Adamson, P.C. and Vassal, G. and Patte, C. and Gross, T.G.
DOI: 10.1056/NEJMoa1915315
2020Healthcare provider utility ratings of a psychosocial screening summary: from diagnosis to 6 months
Supportive Care in Cancer
Desjardins, L. and Etkin-Spigelman, L. and Hancock, K. and Chung, J. and Shama, W. and Mills, D. and Alexander, S. and Barrera, M.
DOI: 10.1007/s00520-019-04969-w
2020Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events
Journal for Immunotherapy of Cancer
Maus, M.V. and Alexander, S. and Bishop, M.R. and Brudno, J.N. and Callahan, C. and Davila, M.L. and Diamonte, C. and Dietrich, J. and Fitzgerald, J.C. and Frigault, M.J. and Fry, T.J. and Holter-Chakrabarty, J.L. and Komanduri, K.V. and Lee, D.W. and Locke, F.L. and Maude, S.L. and McCarthy, P.L. and Mead, E. and Neelapu, S.S. and Neilan, T.G. and Santomasso, B.D. and Shpall, E.J. and Teachey, D.T. and Turtle, C.J. and Whitehead, T. and Grupp, S.A.
DOI: 10.1136/jitc-2020-001511
2020Guideline for antibacterial prophylaxis administration in pediatric cancer and hematopoietic stem cell transplantation
Clinical Infectious Diseases
Lehrnbecher, T. and Fisher, B.T. and Phillips, B. and Alexander, S. and Ammann, R.A. and Beauchemin, M. and Carlesse, F. and Castagnola, E. and Davis, B.L. and Lee Dupuis, L. and Egan, G. and Groll, A.H. and Haeusler, G.M. and Santolaya, M. and Steinbach, W.J. and van de Wetering, M. and Wolf, J. and Cabral, S. and Robinson, P.D. and Sung, L.
DOI: 10.1093/cid/ciz1082
2020Efficacy of antibiotic prophylaxis in patients with cancer and hematopoietic stem cell transplantation recipients: A systematic review of randomized trials
Cancer Medicine
Egan, G. and Robinson, P.D. and Martinez, J.P.D. and Alexander, S. and Ammann, R.A. and Dupuis, L.L. and Fisher, B.T. and Lehrnbecher, T. and Phillips, B. and Cabral, S. and Tomlinson, G. and Sung, L.
DOI: 10.1002/cam4.2395
2019Effect of Caspofungin vs Fluconazole Prophylaxis on Invasive Fungal Disease among Children and Young Adults with Acute Myeloid Leukemia: A Randomized Clinical Trial
JAMA Journal of the American Medical Association
Fisher, B.T. and Zaoutis, T. and Dvorak, C.C. and Nieder, M. and Zerr, D. and Wingard, J.R. and Callahan, C. and Villaluna, D. and Chen, L. and Dang, H. and Esbenshade, A.J. and Alexander, S. and Wiley, J.M. and Sung, L.
DOI: 10.1001/jama.2019.15702
2019Mature B-NHL in children, adolescents and young adults: current therapeutic approach and emerging treatment strategies
British Journal of Haematology
Egan, G. and Goldman, S. and Alexander, S.
DOI: 10.1111/bjh.15734
2019Inotuzumab ozogamicin in pediatric patients with relapsed/refractory acute lymphoblastic leukemia
Leukemia
Bhojwani, D. and Sposto, R. and Shah, N.N. and Rodriguez, V. and Yuan, C. and Stetler-Stevenson, M. and O?Brien, M.M. and McNeer, J.L. and Quereshi, A. and Cabannes, A. and Schlegel, P. and Rossig, C. and Dalla-Pozza, L. and August, K. and Alexander, S. and Bourquin, J.-P. and Zwaan, M. and Raetz, E.A. and Loh, M.L. and Rheingold, S.R.
DOI: 10.1038/s41375-018-0265-z
2019Burkitt Lymphoma and Diffuse Large B-Cell Lymphoma
Non Hodgkins Lymphoma in Childhood and Adolescence
Egan, G. and Weitzman, S. and Alexander, S.
DOI: 10.1007/978-3-030-11769-6_13
2019Pregnancy Screening and Contraceptive Counseling in Young Women with Hodgkin Lymphoma: A Single Center Retrospective Review
Journal of Adolescent and Young Adult Oncology
Wheaton, L. and Alexander, S.
DOI: 10.1089/jayao.2018.0156
2019Chemotherapy-induced nausea and vomiting from oral chemotherapy for childhood acute lymphoblastic leukaemia: feasibility study
BMJ Supportive and Palliative Care
Kovacevic, A. and Sivananthan, A. and Patel, R. and Patel, P. and Vennettilli, A. and Sing, E.P.C. and Zupanec, S. and Alexander, S. and Sung, L. and Dupuis, L.L.
DOI: 10.1136/bmjspcare-2019-002022
2019Correction: Inotuzumab ozogamicin in pediatric patients with relapsed/refractory acute lymphoblastic leukemia (Leukemia, (2018), 10.1038/s41375-018-0265-z)
Leukemia
Bhojwani, D. and Sposto, R. and Shah, N.N. and Rodriguez, V. and Yuan, C. and Stetler-Stevenson, M. and O?Brien, M.M. and McNeer, J.L. and Quereshi, A. and Cabannes, A. and Schlegel, P. and Rossig, C. and Dalla-Pozza, L. and August, K. and Alexander, S. and Bourquin, J.-P. and Zwaan, M. and Raetz, E.A. and Loh, M.L. and Rheingold, S.R.
DOI: 10.1038/s41375-019-0426-8
2019Perceived benefits of and barriers to psychosocial risk screening in pediatric oncology by health care providers
Pediatric Blood & Cancer
Maru Barrera and Sarah Alexander and Wendy Shama and Denise Mills and Leandra Desjardins and Kelly Hancock
DOI: 10.1002/pbc.27429
12/2018Pediatric oncology clinical trial participation where the geography is vast: Development of a clinical research system for tertiary and satellite centers in Ontario, Canada
Pediatric Blood & Cancer
Sarah Alexander and Mark Greenberg and David Malkin and Carol Portwine and Donna Johnston and Mariana Silva and Shayna Zelcer and Samantha Sonshine and Janet Manzo and Carla Bennett and Kathy Brodeur-Robb and Catherine Deveault and Nivetha Ramachandran and Paul Gibson
DOI: 10.1002/pbc.26901
04/2018Effect of levofloxacin prophylaxis on Bacteremia in children with acute Leukemia or undergoing hematopoietic stem cell transplantation a randomized clinical trial
JAMA Journal of the American Medical Association
Alexander, S. and Fisher, B.T. and Gaur, A.H. and Dvorak, C.C. and Luna, D.V. and Dang, H. and Chen, L. and Green, M. and Nieder, M.L. and Fisher, B. and Bailey, L.C. and Wiernikowski, J. and Sung, L.
DOI: 10.1001/jama.2018.12512
2018Non-Hodgkin lymphoma of childhood
Neoplastic Diseases of the Blood
Truong, T.H. and Alexander, S. and Weitzman, S.
DOI: 10.1007/978-3-319-64263-5_46
2018Treatment-related mortality in newly diagnosed pediatric cancer: a population-based analysis
Cancer Medicine
Gibson, P. and Pole, J.D. and Lazor, T. and Johnston, D. and Portwine, C. and Silva, M. and Alexander, S. and Sung, L.
DOI: 10.1002/cam4.1362
2018Outcomes of adults and children with primary mediastinal B-cell lymphoma treated with dose-adjusted EPOCH-R
British Journal of Haematology
Giulino-Roth, L. and O{'}Donohue, T. and Chen, Z. and Bartlett, N.L. and LaCasce, A. and Martin-Doyle, W. and Barth, M.J. and Davies, K. and Blum, K.A. and Christian, B. and Casulo, C. and Smith, S.M. and Godfrey, J. and Termuhlen, A. and Oberley, M.J. and Alexander, S. and Weitzman, S. and Appel, B. and Mizukawa, B. and Svoboda, J. and Afify, Z. and Pauly, M. and Dave, H. and Gardner, R. and Stephens, D.M. and Zeitler, W.A. and Forlenza, C. and Levine, J. and Williams, M.E. and Sima, J.L. and Bollard, C.M. and Leonard, J.P.
DOI: 10.1111/bjh.14951
2017Optimizing autologous nonmobilized mononuclear cell collections for cellular therapy in pediatric patients with high-risk leukemia
Transfusion
Even-Or, E. and Di Mola, M. and Ali, M. and Courtney, S. and McDougall, E. and Alexander, S. and Schechter, T. and Whitlock, J.A. and Licht, C. and Krueger, J.
DOI: 10.1111/trf.14094
2017Guideline for the management of fever and neutropenia in children with cancer and hematopoietic stem-cell transplantation recipients: 2017 update
Journal of Clinical Oncology
Lehrnbecher, T. and Robinson, P. and Fisher, B. and Alexander, S. and Ammann, R.A. and Beauchemin, M. and Carlesse, F. and Groll, A.H. and Haeusler, G.M. and Santolaya, M. and Steinbach, W.J. and Castagnola, E. and Davis, B.L. and Dupuis, L.L. and Gaur, A.H. and Tissing, W.J.E. and Zaoutis, T. and Phillips, R. and Sung, L.
DOI: 10.1200/JCO.2016.71.7017
2017Evaluation of treatment-related mortality among paediatric cancer deaths: A population based analysis
British Journal of Cancer
Pole, J.D. and Gibson, P. and Ethier, M.-C. and Lazor, T. and Johnston, D.L. and Portwine, C. and Silva, M. and Alexander, S. and Sung, L.
DOI: 10.1038/bjc.2016.443
2017Correlation of PET/CT and image-guided biopsies of pediatric malignancies
American Journal of Roentgenology
Nihayah, S. and Shammas, A. and Vali, R. and Parra, D. and Alexander, S. and Amaral, J. and Connolly, B.
DOI: 10.2214/AJR.15.15914
2017Risk stratification in febrile neutropenic episodes in adolescent/young adult patients with cancer
European Journal of Cancer
Phillips, R.S. and Stewart, L.A. and Bhuller, K. and Sung, L. and Ammann, R.A. and Tissing, W.J.E. and Lehrnbecher, T. and Haeusler, G.M. and Bauters, T. and Laureys, G. and Spassova, M. and Klaassen, R. and Alexander, S. and Silva, P. and Tordecilla, J. and Paesmans, M. and Donnelly, J.P. and Simon, A. and Hann, I.M. and Ranasinghe, N. and Riley, R.D. and Chisholm, J. and Yeomanson, D. and Sutton, A.J. and Dommett, R. and Gupta, A. and Castagnola, E. and Haupt, R. and Meidema, K. and Kuehne, T. and Kitanovski, L. and Niggli, F. and Nadal, D. and Tezcan, G. and Hakim, H. and Stryjewski, G.
DOI: 10.1016/j.ejca.2016.05.027
2016Safety and efficacy of intrathecal rituximab in children with B cell lymphoid CD20+ malignancies: An international retrospective study
American Journal of Hematology
Ceppi, F. and Weitzman, S. and Woessmann, W. and Davies, K. and Lassaletta, A. and Reism{\"u}ller, B. and Mellgren, K. and Uyttebroeck, A. and Maia, I. and Abdullah, S. and Miakova, N. and Glaser, D. and Cohn, R. and Abla, O. and Attarbaschi, A. and Alexander, S.
DOI: 10.1002/ajh.24329
2016Cardioprotection and second malignant neoplasms associated With dexrazoxane in children receiving anthracycline chemotherapy: A systematic review and meta-Analysis
Journal of the National Cancer Institute
Shaikh, F. and Dupuis, L.L. and Alexander, S. and Gupta, A. and Mertens, L. and Nathan, P.C.
DOI: 10.1093/jnci/djv357
2016A Feasibility Pilot Trial of Individualized Homeopathic Treatment of Fatigue in Children Receiving Chemotherapy
Integrative Cancer Therapies
Brul{\'e}, D. and Gillmeister, B. and Lee, M. and Alexander, S. and Gassas, A. and Hendershot, E. and Zupanec, S. and Dupuis, L. and Sung, L.
DOI: 10.1177/1534735415617023
2016Non-anaplastic peripheral T cell lymphoma in children and adolescents—an international review of 143 cases
Annals of Hematology
Mellgren, K. and Attarbaschi, A. and Abla, O. and Alexander, S. and Bomken, S. and Bubanska, E. and Chiang, A. and Cs{\'o}ka, M. and Fedorova, A. and Kabickova, E. and Kapuscinska-Kemblowska, L. and Kobayashi, R. and Krenova, Z. and Meyer-Wentrup, F. and Miakova, N. and Pillon, M. and Plat, G. and Uyttebroeck, A. and Williams, D. and Wr{\'o}bel, G. and Kontny, U.
DOI: 10.1007/s00277-016-2722-y
2016Impact of ethnicity on donor search results for children requiring stem cell transplantation
Journal of Pediatric Hematology Oncology
Dilabio, J. and Doyle, J. and Alexander, S. and Gupta, S. and Punnett, A.
DOI: 10.1097/MPH.0000000000000273
2015Prevention of infection
Pediatric Oncology
Fisher, B.T. and Dvorak, C.C. and Alexander, S.
DOI: 10.1007/978-3-662-44317-0_14
2015Risk factors for inadequate bone marrow biopsies in children
American Journal of Hematology
Grant, R.C. and Shaikh, F. and Abdelhaleem, M. and Alexander, S.W. and Cada, M.
DOI: 10.1002/ajh.24078
2015Differences in end-of-life communication for children with advanced cancer who were referred to a palliative care team
Pediatric Blood and Cancer
Kassam, A. and Skiadaresis, J. and Alexander, S. and Wolfe, J.
DOI: 10.1002/pbc.25530
2015Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
Nature Genetics
Shlien, A. and Campbell, B.B. and De Borja, R. and Alexandrov, L.B. and Merico, D. and Wedge, D. and Van Loo, P. and Tarpey, P.S. and Coupland, P. and Behjati, S. and Pollett, A. and Lipman, T. and Heidari, A. and Deshmukh, S. and Avitzur, N. and Meier, B. and Gerstung, M. and Hong, Y. and Merino, D.M. and Ramakrishna, M. and Remke, M. and Arnold, R. and Panigrahi, G.B. and Thakkar, N.P. and Hodel, K.P. and Henninger, E.E. and G{\"o}ksenin, A.Y. and Bakry, D. and Charames, G.S. and Druker, H. and Lerner-Ellis, J. and Mistry, M. and Dvir, R. and Grant, R. and Elhasid, R. and Farah, R. and Taylor, G.P. and Nathan, P.C. and Alexander, S. and Ben-Shachar, S. and Ling, S.C. and Gallinger, S. and Constantini, S. and Dirks, P. and Huang, A. and Scherer, S.W. and Grundy, R.G. and Durno, C. and Aronson, M. and Gartner, A. and Meyn, M.S. and Taylor, M.D. and Pursell, Z.F. and Pearson, C.E. and Malkin, D. and Futreal, P.A. and Stratton, M.R. and Bouffet, E. and Hawkins, C. and Campbell, P.J. and Tabori, U.
DOI: 10.1038/ng.3202
2015Classification of treatment-related mortality in children with cancer: A systematic assessment
Lancet Oncology
Alexander, S. and Pole, J.D. and Gibson, P. and Lee, M. and Hesser, T. and Chi, S.N. and Dvorak, C.C. and Fisher, B. and Hasle, H. and Kanerva, J. and M{\"o}ricke, A. and Phillips, B. and Raetz, E. and Rodriguez-Galindo, C. and Samarasinghe, S. and Schmiegelow, K. and Tissing, W. and Lehrnbecher, T. and Sung, L.
DOI: 10.1016/S1470-2045(15)00197-7
2015Olanzapine for treatment and prevention of acute chemotherapy-induced vomiting in children: A retrospective, multi-center review
Pediatric Blood and Cancer
Flank, J. and Thackray, J. and Nielson, D. and August, A. and Schechter, T. and Alexander, S. and Sung, L. and Dupuis, L.L.
DOI: 10.1002/pbc.25286
2015Parent and clinician preferences for location of end-of-life care: Home, hospital or freestanding hospice?
Pediatric Blood and Cancer
Kassam, A. and Skiadaresis, J. and Alexander, S. and Wolfe, J.
DOI: 10.1002/pbc.24872
2014The risk of traumatic lumbar punctures in children with acute lymphoblastic leukaemia
European Journal of Cancer
Shaikh, F. and Voicu, L. and Tole, S. and To, T. and Doria, A.S. and Sung, L. and Alexander, S.
DOI: 10.1016/j.ejca.2014.02.021
2014Lack of treatment-related mortality definitions in clinical trials of children, adolescents and young adults with lymphomas, solid tumors and brain tumors: A systematic review
BMC Cancer
Tran, T.H. and Lee, M. and Alexander, S. and Gibson, P. and Bartels, U. and Johnston, D.L. and Portwine, C. and Silva, M. and Pole, J.D. and Sung, L.
DOI: 10.1186/1471-2407-14-612
2014Clinically defining and managing high-risk pediatric patients with acute lymphoblastic leukemia
Hematology United States
Alexander, S.
DOI: 10.1182/asheducation-2014.1.181
2014Methylnaltrexone for Opioid-Induced Constipation in Pediatric Oncology Patients
Pediatric Blood and Cancer
Rodrigues, A. and Wong, C. and Mattiussi, A. and Alexander, S. and Lau, E. and Dupuis, L.L.
DOI: 10.1002/pbc.24615
2013Ultrasound imaging for lumbar punctures and epidural catheterisations: Systematic review and meta-analysis
BMJ Online
Shaikh, F. and Brzezinski, J. and Alexander, S. and Arzola, C. and Carvalho, J.C.A. and Beyene, J. and Sung, L.
DOI: 10.1136/bmj.f1720
2013Primary conjunctival anaplastic large cell lymphoma in a child
Journal of AAPOS
Kirwan, C. and Ngan, B.-Y. and Halliday, W. and Alexander, S. and Ali, A.
DOI: 10.1016/j.jaapos.2013.04.005
2013Moving toward quality palliative cancer care: Parent and clinician perspectives on gaps between what matters and what is accessible
Journal of Clinical Oncology
Kassam, A. and Skiadaresis, J. and Habib, S. and Alexander, S. and Wolfe, J.
DOI: 10.1200/JCO.2012.44.8936
2013Progressive transformation of germinal centers in children and adolescents: An intriguing cause of lymphadenopathy
Pediatric Blood and Cancer
Shaikh, F. and Ngan, B.-Y. and Alexander, S. and Grant, R.
DOI: 10.1002/pbc.24234
2013Discrete Choice Experiment to Evaluate Factors That Influence Preferences for Antibiotic Prophylaxis in Pediatric Oncology
Plos One
Regier, D.A. and Diorio, C. and Ethier, M.-C. and Alli, A. and Alexander, S. and Boydell, K.M. and Gassas, A. and Taylor, J. and Kellow, C. and Mills, D. and Sung, L.
DOI: 10.1371/journal.pone.0047470
2012Peripheral T-cell lymphoma in children and adolescents: A single-institution experience
Journal of Pediatric Hematology Oncology
Al Mahmoud, R. and Weitzman, S. and Schechter, T. and Ngan, B. and Abdelhaleem, M. and Alexander, S.
DOI: 10.1097/MPH.0b013e3182707592
2012Epidemiology and potential preventative measures for viral infections in children with malignancy and those undergoing hematopoietic cell transplantation
Pediatric Blood and Cancer
Fisher, B.T. and Alexander, S. and Dvorak, C.C. and Zaoutis, T.E. and Zerr, D.M. and Sung, L.
DOI: 10.1002/pbc.23417
2012Antifungal prophylaxis in pediatric hematology/oncology: New choices & new data
Pediatric Blood and Cancer
Dvorak, C.C. and Fisher, B.T. and Sung, L. and Steinbach, W.J. and Nieder, M. and Alexander, S. and Zaoutis, T.E.
DOI: 10.1002/pbc.23415
2012Prevention of bacterial infection in pediatric oncology: What do we know, what can we learn?
Pediatric Blood and Cancer
Alexander, S. and Nieder, M. and Zerr, D.M. and Fisher, B.T. and Dvorak, C.C. and Sung, L.
DOI: 10.1002/pbc.23416
2012Pneumatosis intestinalis in children with acute lymphoblastic leukemia and acute myeloid leukemia
Supportive Care in Cancer
Li, S. and Traubici, J. and Ethier, M.-C. and Gillmeister, B. and Alexander, S. and Gassas, A. and Sung, L.
DOI: 10.1007/s00520-011-1088-x
2012Fluoroquinolones in children with fever and neutropenia: A systematic review of prospective trials
Pediatric Infectious Disease Journal
Sung, L. and Manji, A. and Beyene, J. and Dupuis, L.L. and Alexander, S. and Phillips, R. and Lehrnbecher, T.
DOI: 10.1097/INF.0b013e318245ab48
2012Attitudes toward Infection Prophylaxis in Pediatric Oncology: A Qualitative Approach
Plos One
Diorio, C. and Tomlinson, D. and Boydell, K.M. and Regier, D.A. and Ethier, M.-C. and Alli, A. and Alexander, S. and Gassas, A. and Taylor, J. and Kellow, C. and Mills, D. and Sung, L.
DOI: 10.1371/journal.pone.0047815
2012Association between obesity at diagnosis and weight change during induction and survival in pediatric acute lymphoblastic leukemia
Leukemia and Lymphoma
Ethier, M.-C. and Alexander, S. and Abla, O. and Green, G. and Lam, R. and Sung, L.
DOI: 10.3109/10428194.2012.664843
2012Updated systematic review and meta-analysis of the performance of risk prediction rules in children and young people with febrile neutropenia
Plos One
Phillips, R.S. and Lehrnbecher, T. and Alexander, S. and Sung, L.
DOI: 10.1371/journal.pone.0038300
2012The utility of end-of-treatment bone marrow aspirates in pediatric acute lymphoblastic leukemia: A quality improvement project
Pediatric Blood and Cancer
Gupta, S. and Crump, H.L. and Alexander, S.
DOI: 10.1002/pbc.24204
2012Non-relapse mortality in pediatric acute lymphoblastic leukemia: A systematic review and meta-analysis
Leukemia and Lymphoma
Blanco, E. and Beyene, J. and Maloney, A.M. and Almeida, R. and Ethier, M.-C. and Winick, N. and Alexander, S. and Sung, L.
DOI: 10.3109/10428194.2011.639018
2012Guideline for the management of fever and neutropenia in children with cancer and/or undergoing hematopoietic stem-cell transplantation
Journal of Clinical Oncology
Lehrnbecher, T. and Phillips, R. and Alexander, S. and Alvaro, F. and Carlesse, F. and Fisher, B. and Hakim, H. and Santolaya, M. and Castagnola, E. and Davis, B.L. and Lee Dupuis, L. and Gibson, F. and Groll, A.H. and Gaur, A. and Gupta, A. and Kebudi, R. and Petrilli, S. and Steinbach, W.J. and Villarroel, M. and Zaoutis, T. and Sung, L.
DOI: 10.1200/JCO.2012.42.7161
2012US-guided percutaneous needle biopsy of anterior mediastinal masses in children
Pediatric Radiology
McCrone, L. and Alexander, S. and Karsli, C. and Taylor, G. and Amaral, J.G. and Parra, D. and Temple, M. and John, P. and Connolly, B.L.
DOI: 10.1007/s00247-011-2204-2
2012Hematopoietic stem-cell transplantation following solid-organ transplantation in children
Bone Marrow Transplantation
Schechter-Finkelstein, T. and Gassas, A. and Weitzman, S. and Grant, D. and Pollock-Barziv, S. and Dipchand, A. and Alexander, S. and Ali, M. and Avitzur, Y. and Doyle, J.
DOI: 10.1038/bmt.2011.153
2011Quality of life during active treatment for pediatric acute lymphoblastic leukemia
International Journal of Cancer
Sung, L. and Yanofsky, R. and Klaassen, R.J. and Dix, D. and Pritchard, S. and Winick, N. and Alexander, S. and Klassen, A.
DOI: 10.1002/ijc.25433
2011Prophylactic therapy with Fibrogammin® P is associated with a decreased incidence of bleeding episodes: A retrospective study
Haemophilia
Lusher, J. and Pipe, S.W. and Alexander, S. and Nugent, D.
DOI: 10.1111/j.1365-2516.2009.02123.x
2010Bleeding symptoms and laboratory correlation in patients with severe von Willebrand disease
Haemophilia
Metjian, A.D. and Wang, C. and Sood, S.L. and Cuker, A. and Peterson, S.M. and Soucie, J.M. and Konkle, B.A. and Boyd, M. and Roy, G. and Forman, E. and Marandola, J. and Homans, A.C. and Granat, M. and Lusher, J. and Fleming, P. and DiMichele, D. and Goldberg, I. and Saidi, P. and Schwartz, R. and Desposito, F. and Joseph, D. and Kouides, P.A. and La Franco, J. and Coyle, T. and Dhar, N. and Porter, J. and Frank, M. and Lipton, R. and Bosch, M. and Holmberg, R.P. and Menza, L. and Cohen, A. and White, E. and Guerrera, M. and Guelcher, C. and Kessler, C. and Jacobs, H. and Massey, G. and Nolte, M. and Werner, E. and Stewart, K. and Ragni, M. and Jaworski, K. and Rogers, J.S. and Webber, S. and Jubelirer, S. and Arden, D. and Casella, J. and Underland, T. and Panckeri, K. and Palumbo, L. and Sabio, H. and Smith, A. and Sharma, V. and Ashby, P. and Radulescu, V. and Hanna, W. and Zimmerman, C. and Neff, A. and Hudson, M.G. and Reiss, U. and Grant, R. and Key, N. and Nielsen, B. and Dunn, A. and Gutting, K. and Watts, R. and Noa, M.C. and Abshire, T. and Bryant, C. and Ameri, A. and Crenshaw, V. and Kuriakose, P. and Lambing, A. and Heggie, G. and Kovats-Bell, S. and Inoue, S. and Ruff, J.A. and Mitchell, D. and Sandon-Kleiboer, E. and Kraut, E. and Witkoff, W. and Gruppo, R. and Chambers, A. and Kerlin, B. and Lupia, C. and French, J. and Hibner, S. and Shapiro, A. and May, S. and Alexander, S. and Hopewell, S. and Bockenstedt, P. and Pipe, S. and Mathis, D. and Zakarija, A. and Harris, S. and Thompson, A. and Allen, G.A. and Brummel, A.T. and Tarantino, M. and Riedel, A. and Reding, M. and Curoe, S. and Pruthi, R. and Schmidt, K. and Kralovetz, K. and Charles, J. and Diamond, C. and Drozdowicz, P. and Gill, J.C. and Haar, J. and Hoots, W.K. and Gonzalez, V. and Leissinger, C. and Schmidt, C.V. and Stine, K. and Eckert, G. and Sexauer, C. and Kiplinger, F. and Amerson, P. and Johnson, E. and Buchanan, G. and Torres, R. and DiPaola, J. and Lammer, M. and Wicklund, B. and Nelson, D. and Haire, W.D. and Hanlon, E. and Manco-Johnson, M. and Geraghty, S. and Yaish, H. and Green, J. and Young, G. and McGinty, K. and Herbst, K. and Glass, C. and Glader, B. and Zoland, J.M. and Medeiros, D. and Omatsu, D.A. and Ducore, J. and Herr, M. and Koerper, M. and Karp, S. and Lovejoy, A.E. and Farrow, K. and Ewing, N. and Pullens, L. and Meadows, L. and Tackney, A. and Mignacca, R. and Patterson, F. and Bernstein, J. and Berkowitz, B. and Thompson, A.R. and Brower, C. and Recht, M. and Granger, K. and Schulz, L. and Stewart, A.
DOI: 10.1111/j.1365-2516.2009.02025.x
2009Hereditary persistence of alpha-fetoprotein
Pediatric Blood and Cancer
Li, X. and Alexander, S.
DOI: 10.1002/pbc.21816
2009Rituximab and desensitization for a patient with severe factor IX deficiency, inhibitors, and history of anaphylaxis
Journal of Pediatric Hematology Oncology
Alexander, S. and Hopewell, S. and Hunter, S. and Chouksey, A.
DOI: 10.1097/MPH.0b013e31815cf742
2008Evaluation of prolonged aPTT values in the pediatric population
Clinical Pediatrics
Shah, M.D. and O{'}Riordan, M.A. and Alexander, S.W.
DOI: 10.1177/000992280604500407
2006Solid tumors of childhood
Oncology an Evidence Based Approach
Strunk, C.J. and Alexander, S.W.
DOI: 10.1007/0-387-31056-8_62
2006Ovarian Toxicity after Chemotherapy: Possible Association with Ifosfamide Administration
Pediatric Blood and Cancer
Palmert, M.R. and Alexander, S.W. and Goorin, A.M.
DOI: 10.1002/pbc.10320
2004Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosis
Blood
Fleming, M.D. and Pinkus, J.L. and Alexander, S.W. and Tam, C. and Loda, M. and Sallan, S.E. and Nichols, K.E. and Carpentieri, D.F. and Pinkus, G.S. and Rollins, B.J.
DOI: 10.1182/blood.V101.7.2473
2003Evaluation of risk prediction criteria for episodes of febrile neutropenia in children with cancer
Journal of Pediatric Hematology Oncology
Alexander, S.W. and Wade, K.C. and Hibberd, P.L. and Parsons, S.K.
DOI: 10.1097/00043426-200201000-00011
2002Functional consequences of perforin gene mutations in 22 patients with familial haemophagocytic lymphohistiocytosis
British Journal of Haematology
Feldmann, J. and Le Deist, F. and Ouach{\'e}e-Chardin, M. and Certain, S. and Alexander, S. and Quartier, P. and Haddad, E. and Wulffraat, N. and Casanova, J.L. and Blanche, S. and Fischer, A. and De Saint Basile, G.
DOI: 10.1046/j.1365-2141.2002.03534.x
2002Growth factor practice patterns among pediatric oncologists: Results of a 1998 pediatric oncology group survey
American Journal of Pediatric Hematology Oncology
Parsons, S.K. and Mayer, D.K. and Alexander, S.W. and Xu, R. and Land, V. and Laver, J.
DOI: 10.1097/00043426-200005000-00008
2000Current considerations in the management of fever and neutropenia
Current Clinical Topics in Infectious Diseases
Alexander, S.W. and Pizzo, P.A.
1999 - Research
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Evaluation of the impacts of blinatumomab on infectious toxicity and laboratory measures of immune function in children with acute lymphoblastic leukemia
The addition of blinatumomab, a type of immunotherapy, to conventional chemotherapy for children and adults with acute lymphoblastic leukemia (ALL) increases the chance of cure. A side effect of blinatumomab is decreasing healthy B cells. These cells are part of the immune system and are important in making immune globulin, which help protect individuals from infections. This research focuses on understanding the impacts of the addition on blinatumomab in children treated for ALL on risks of infection and strategies to minimize these risks, including immune globulin replacement.Optimizing therapy for children with mature B non Hodgkin lymphoma, with biological risk stratification and de-intensification of conventional chemotherapy
Children and adolescents with mature B cell lymphoma (Burkittt lymphoma and diffuse large B cell lymphoma) have a high chance of being cured with combination immunochemotherapy. Current therapy comes with substantive risks of short term side effects and some risks of longer term side effects. This research focuses on identifying patients, based on clinical features and tumor biology, that can receive less intensive chemotherapy, with a goal of preserving excellent chance of cure but doing so with less toxicity.Strategies for vaccination of children following cancer immunochemotherapy
Optimal therapy for children with various types of cancer now uses both conventional chemotherapy and immunotherapy. Little is known about the impacts of this treatment on protection from standard childhood vaccine preventable infections. This research will evaluate the impacts of cancer therapy on vaccine serologies and strategies for optimizing protection post completion of cancer therapy.
Congratulations to the winners of the Nobel Prize in Physiology or Medicine 2025
The Nobel Prize in Physiology or Medicine 2025 was awarded to Dr. Mary E. Brunkow, Dr. Fred Ramsdell, and Dr. Shimon Sakaguchi for their discoveries concerning peripheral immune tolerance. BCCHR's Dr. Megan Levings reflects on the significance of this area of research and how these immune cells could develop treatments for numerous diseases such as type 1 diabetes, multiple sclerosis, organ rejection, and more.
