Childhood Diseases

Conducting world-class research in immunity, rare diseases, childhood cancer, blood disorders, and diabetes.

We’re Dedicated to Improving Diagnoses and Treatments

The Childhood Diseases Theme focuses on studying childhood diseases and disorders. We’re dedicated to discovering how the body responds to illness, with a specific focus on understanding the mechanisms of health versus disease, as well as identifying and testing new diagnostic and therapeutic approaches.

Specialized research groups provide the opportunity for BCCHR scientists and clinicians with similar research interests to connect and collaborate, regardless of their theme affiliations. While each group is supported by at least one theme, researchers can be part of any group from any theme. The Childhood Diseases Theme has four specialized research groups that are focused on studying childhood diseases and disorders: Childhood Cancer and Blood Research, Diabetes, Immunity in Health and Disease, and Rare Diseases.

Childhood Cancer and Blood Research

Lead: Christopher Maxwell

In the Childhood Cancer and Blood Research Group, clinicians and scientists work together to conduct research that improves the lives of children and young adults with cancer and/or blood disorders, and those undergoing transplantation.

Many of our Childhood Cancer & Blood Research scientists are generously supported by the Michael Cuccione Foundation through the Michael Cuccione Childhood Cancer Research Program (MCCCRP).

Diabetes

Lead: Francis Lynn

Through transformative research, the Diabetes Group strives to improve the lives of children and families living with diabetes. Our researchers are dedicated to making prediction, prevention, new treatments, and a cure a reality.

You can also visit the Canucks for Kids Fund Childhood Diabetes Laboratories website to learn more about our work.

Immunity in Health and Disease

Lead: Laura Sly

Researchers in the Immunity in Health and Disease Group are focused on improving our understanding of healthy immune responses and how the immune system contributes to immune-mediated diseases in children.

Rare Diseases

Lead: Catherine Biggs

The Rare Disease Group envisions becoming a patient-centred leader in the field of rare disease discovery and innovation with the aim of improving outcomes for rare disease patients in British Columbia and beyond.

Childhood Diseases Core Personnel

We work together with our members to support research and encourage education, innovation, and knowledge translation.

Philipp Lange

Theme Director

Dr. Lange is an Investigator in the Michael Cuccione Childhood Cancer Research Program at BC Children’s Hospital and an Associate Professor in the Department of Pathology at UBC. As Theme Director, Dr. Lange promotes and facilitates research and supports collaboration, education, knowledge sharing, and mentorship.

Jeffrey Helm

Theme Research Manager

Jeffrey has master’s degrees in Neuroscience and Journalism and more than 15 years of experience in research administration. As Theme Research Manager, he values collaboration and works with researchers to identify their needs and develop infrastructure to meet those needs.

Emily Fox

Theme Research Coordinator

Emily received a Bachelor of Arts degree in Psychology and Sociology from UBC. As Theme Research Coordinator, she supports researchers in the planning, management, and communication of research activities.

Lab, Project & Program Websites

Find out more about some of the labs, projects, and programs at BC Children’s Hospital Research Institute.

BC Children’s Hospital BioBank

visit site

Biochemical Genetics Clinic

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Canadian Autoimmunity Standardization Core

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Canucks for Kids Fund Childhood Diabetes Laboratories

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Cellular and Regenerative Medicine Centre

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Children’s Heart Centre Research

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Division of Endocrinology

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Division of Nephrology Research

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Division of Rheumatology

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Food Allergy Immunotherapy Program

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Division of Pediatric Gastroenterology, Hepatology and Nutrition

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GenCOUNSEL Project

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Gut4Health

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Levings Lab

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Lynn Lab

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Maxwell Lab

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Michael Cuccione Childhood Cancer Research Program

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Pregnancy & Pediatric Reference Intervals for Safe Medicine

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Sanatani Lab

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Silent Genomes Project

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Solid Organ Transplant Research

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The BRAvE Initiative

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Trainee ‘Omics Group

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Ustekinumab to Treat Type 1 Diabetes

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Vallance Lab

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Research News

Every day, BCCHR researchers work towards breakthroughs to transform the lives of kids in BC and around the world. Learn about our latest innovations and advancements in child health.

  • News

    Collaboration led by BCCHR researchers awarded European funding to improve community-based care in Uganda and Kenya

    Dr. Matthew Wiens and colleagues at the Institute for Global Health at BC Children’s & Women’s Hospital, BC Children’s Research Institute, and the University of British Columbia, are the first Canadian Team to lead a Horizon Europe Pillar 2 project. The consortium was recently awarded €5 million under the Global Health EDCTP3 Joint Undertaking for a project that…

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  • High School Student Events

    Mini Med School Prince George

    Mini Med School will be on the road for years to come! We want to give as many communities as possible the opportunity to interact with BC Children’s Hospital’s world-class researchers and clinicians. For 2025, Mini Med School BC will be in Whitehorse, Yukon for the first time!

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  • High School Student Events

    Women in Science

    Join us as we celebrate the 2026 International Day of Women and Girls in Science. At BC Children’s Hospital and BC Women’s Hospital + Health Centre, we are proud to support the next generation of health scientists. At this unique event, designed specifically for grade 11-12 students, you will have the opportunity to connect with inspiring…

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Donate to Research

With your support, we believe there’s nothing we can’t do. Funding helps bring hope out of the laboratory and into the clinic — to save and improve children’s lives.

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