While growing up, Abisola Kehinde was fascinated by biology, one of those courses she didn’t have to study much to easily understand. It was natural to her, so choosing a career in science was a no-brainer. She was never told that, as a woman, there wasn’t space for her in this field. But there were other challenges related to gender biases.
The fetal brain is unique among fetal organs in that it undergoes profound changes throughout pregnancy, some of which are transient in that they appear and disappear as the brain matures.
With ultrasound and fetal MRI, we have a unique opportunity to look at the fetal brain while it is developing. I use special techniques with ultrasound and magnetic resonance imaging to look at the fetal brain at different stages of pregnancy. Our technique is a new way to assess brain tissue which allows us to evaluate milestones in normal development.
Understanding the imaging appearance of the normal brain is critical in recognizing abnormal development, whether due to a malformation, genetic defect, an infection in pregnancy, bleeding in the brain, or other signs of brain damage. My research focuses on identifying fetuses at risk for prenatal brain damage, with the goal of understanding why it happens and what we can do to prevent it
Quantitative ultrasound for detecting abnormalities of the placenta: Measuring the stiffness of the placenta to help diagnose fetal growth restriction.
Shear wave absolute vibro-elastography of the placenta. The objectives of this study are to define SWAVE characteristics in the normal placenta. SWAVE is a potentially valuable new tool to explore placental function and health in both the clinical and research settings.
Postmortem MRI (3 Tesla at the CFRIF Research Facility) and ultrasound imaging. We are developing strategies to look at different aspects of fetal development, and in particular, brain maturation including myelination. Comparison with antenatal MRI and ultrasound, as well as autopsy information, is being performed.Grants
Canadian Foundation for Innovation - PI: PRIME Research Facility at BC Women's Hospital and Health Centre, 2015
CHRP; Coinvestigator, 2016
VCHRI Innovation and Translational Research Award, Coinvestigator, 2016Research Group Members
Nick Garbuz, Research Team Member