Elizabeth Conibear
PhD
Investigator, BC Children's Hospital
Principal Investigator and Scientist, Centre for Molecular Medicine and Therapeutics
Journal of Cell Biology
Samantha K. Dziurdzik and Vaishnavi Sridhar and Hailey Eng and Sarah D. Neuman and Junran Yan and Michael Davey and Stefan Taubert and Arash Bashirullah and Elizabeth Conibear
DOI: 10.1083/jcb.20250213105 / 2026
Mitchell Leih and Michaela McCright and Cortney Angers and Michael Davey and Elizabeth Conibear and Alex Merz and Greg Odorizzi
DOI: 10.64898/2026.02.13.70576902 / 2026
Nature Structural & Molecular Biology
Cristian Rocha-Roa and Paige Chandran Blair and Gurpreet Sidhu and Daniel lvarez and Michael Davey and Elizabeth Conibear and Stefano Vanni
DOI: 10.1038/s41594-025-01716-002 / 2026
Mia S. Frier and Shawn P. Shortill and Michael Davey and Elizabeth Conibear
DOI: 10.64898/2026.01.27.70213201 / 2026
Proceedings of the National Academy of Sciences
Daniel lvarez and Paige Chandran Blair and Cristian Rocha-Roa and Michael Davey and Elizabeth Conibear and Stefano Vanni
DOI: 10.1073/pnas.252039912301 / 2026
Biorxiv
Jeffers, K.R. and Dziurdzik, S.K. and Davey, M. and Conibear, E.
DOI: 10.1101/2025.08.12.669934Biorxiv
Rocha-Roa, C. and Sidhu, G. and Blair, P.C. and ?lvarez, D. and Davey, M. and Conibear, E. and Vanni, S.
DOI: 10.1101/2025.04.30.651444Biorxiv
Dziurdzik, S.K. and Sridhar, V. and Eng, H. and Neuman, S.D. and Yan, J. and Davey, M. and Taubert, S. and Bashirullah, A. and Conibear, E.
DOI: 10.1101/2025.02.11.637747Journal of Cell Biology
Holme, S. and Sapia, J. and Davey, M. and Vanni, S. and Conibear, E.
DOI: 10.1083/jcb.202405042Shawn P. Shortill and Mia S. Frier and Michael Davey and Elizabeth Conibear
DOI: 10.1101/2024.01.24.57675501 / 2024
Molecular biology of the cell
Shortill, S.P. and Frier, M.S. and Davey, M. and Conibear, E.
DOI: 10.1091/mbc.E24-01-0043bioRxiv
Holme, S. and Sapia, J. and Davey, M. and Vanni, S. and Conibear, E.
DOI: 10.1101/2024.05.14.594217Microbial Cell Factories
Strawn, G. and Wong, R.W.K. and Young, B.P. and Davey, M. and Nislow, C. and Conibear, E. and Loewen, C.J.R. and Mayor, T.
DOI: 10.1186/s12934-024-02298-0Garrett Strawn and Ryan Wong and Barry Young and Michael Davey and Corey Nislow and Elizabeth Conibear and Christopher Loewen and Thibault Mayor
DOI: 10.1101/2023.07.10.54837307 / 2023
eLife
Shortill, S.P. and Frier, M.S. and Wongsangaroonsri, P. and Davey, M. and Conibear, E.
DOI: 10.7554/eLife.77035Current Opinion in Cell Biology
Shortill, S.P. and Frier, M.S. and Conibear, E.
DOI: 10.1016/j.ceb.2022.102087International Journal of Molecular Sciences
Samantha Dziurdzik and Elizabeth Conibear
DOI: 10.3390/ijms2206290503 / 2021
bioRxiv
Castro, I.G. and Shortill, S.P. and Dziurdzik, S.K. and Cadou, A. and Ganesan, S. and Fenech, E.J. and Meyer, H. and Fadel, A. and David, Y. and Davey, M. and Mattes, C. and Valenti, R. and Ernst, R. and Zaremberg, V. and Levine, T.P. and Stefan, C.J. and Conibear, E. and Schuldiner, M.
DOI: 10.1101/2021.10.17.464712bioRxiv
Ulengin-Talkish, I. and Parson, M.A.H. and Jenkins, M.L. and Roy, J. and Shih, A.Z.L. and St-Denis, N. and Gulyas, G. and Balla, T. and Gingras, A.-C. and Vrnai, P. and Conibear, E. and Burke, J.E. and Cyert, M.S.
DOI: 10.1101/2021.07.14.451536bioRxiv
Shortill, S.P. and Frier, M.S. and Davey, M. and Conibear, E.
DOI: 10.1101/2021.11.29.470412The FASEB Journal
Idil Ulengin-Talkish and Rachel Bond and Nicole St-Denis and Anne-Claude Gingras and Alexis Shih and Elizabeth Conibear and Tamas Balla and Peter Varnai and Martha S. Cyert
DOI: 10.1096/fasebj.2020.34.s1.0759304 / 2020
Human Molecular Genetics
Dziurdzik, S.K. and Bean, B.D.M. and Davey, M. and Conibear, E.
DOI: 10.1093/hmg/ddz318bioRxiv
Dziurdzik, S.K. and Bean, B.D.M. and Davey, M. and Conibear, E.
DOI: 10.1101/768366Journal of Cell Biology
Bean, B.D.M. and Dziurdzik, S.K. and Kolehmainen, K.L. and Fowler, C.M.S. and Kwong, W.K. and Grad, L.I. and Davey, M. and Schluter, C. and Conibear, E.
DOI: 10.1083/JCB.201804111Traffic
Dharwada, S.T. and Dalton, L.E. and Bean, B.D.M. and Padmanabhan, N. and Choi, C. and Schluter, C. and Davey, M. and Conibear, E.
DOI: 10.1111/tra.12553Contact
Dziurdzik, S.K. and Bean, B.D.M. and Conibear, E.
DOI: 10.1177/2515256418814621Molecular Biology of the Cell
Dalton, L.E. and Bean, B.D.M. and Davey, M. and Conibear, E.
DOI: 10.1091/mbc.E16-11-0772Traffic
Bean, B.D.M. and Davey, M. and Conibear, E.
DOI: 10.1111/tra.12459Biochemical Society Transactions
Lin, D.T.S. and Davis, N.G. and Conibear, E.
DOI: 10.1042/BST20160303Molecular Biology of the Cell
Whitfield, S.T. and Burston, H.E. and Bean, B.D.M. and Raghuram, N. and Maldonado-Bez, L. and Davey, M. and Wendland, B. and Conibear, E.
DOI: 10.1091/mbc.E15-09-0621Methods in Molecular Biology
Dalton, L. and Davey, M. and Conibear, E.
DOI: 10.1007/978-1-4939-2309-0_27Molecular Biology of the Cell
Bean, B.D.M. and Davey, M. and Snider, J. and Jessulat, M. and Deineko, V. and Tinney, M. and Stagljar, I. and Babu, M. and Conibear, E.
DOI: 10.1091/mbc.E14-08-1281Biochemical Society Transactions
Lin, D.T.S. and Conibear, E.
DOI: 10.1042/BST20140235eLife
Lin, D.T.S. and Conibear, E.
DOI: 10.7554/eLife.11306Orphanet Journal of Rare Diseases
Stockler, S. and Corvera, S. and Lambright, D. and Fogarty, K. and Nosova, E. and Leonard, D. and Steinfeld, R. and Ackerley, C. and Shyr, C. and Au, N. and Selby, K. and Van Allen, M. and Vallance, H. and Wevers, R. and Watkins, D. and Rosenblatt, D. and Ross, C.J. and Conibear, E. and Wasserman, W. and Van Karnebeek, C.
DOI: 10.1186/s13023-014-0141-5Human Molecular Genetics
Butland, S.L. and Sanders, S.S. and Schmidt, M.E. and Riechers, S.-P. and Lin, D.T.S. and Martin, D.D.O. and Vaid, K. and Graham, R.K. and Singaraja, R.R. and Wanker, E.E. and Conibear, E. and Hayden, M.R.
DOI: 10.1093/hmg/ddu137Molecular biology of the cell
Conibear, E. and Nichols, B.J.
DOI: 10.1091/mbc.e12-12-0875Nature
Babu, M. and Vlasblom, J. and Pu, S. and Guo, X. and Graham, C. and Bean, B.D.M. and Burston, H.E. and Vizeacoumar, F.J. and Snider, J. and Phanse, S. and Fong, V. and Tam, Y.Y.C. and Davey, M. and Hnatshak, O. and Bajaj, N. and Chandran, S. and Punna, T. and Christopolous, C. and Wong, V. and Yu, A. and Zhong, G. and Li, J. and Stagljar, I. and Conibear, E. and Wodak, S.J. and Emili, A. and Greenblatt, J.F.
DOI: 10.1038/nature11354American Journal of Human Genetics
Vilario-Gell, C. and Wider, C. and Ross, O.A. and Dachsel, J.C. and Kachergus, J.M. and Lincoln, S.J. and Soto-Ortolaza, A.I. and Cobb, S.A. and Wilhoite, G.J. and Bacon, J.A. and Behrouz, B. and Melrose, H.L. and Hentati, E. and Puschmann, A. and Evans, D.M. and Conibear, E. and Wasserman, W.W. and Aasly, J.O. and Burkhard, P.R. and Djaldetti, R. and Ghika, J. and Hentati, F. and Krygowska-Wajs, A. and Lynch, T. and Melamed, E. and Rajput, A. and Rajput, A.H. and Solida, A. and Wu, R.-M. and Uitti, R.J. and Wszolek, Z.K. and Vingerhoets, F. and Farrer, M.J.
DOI: 10.1016/j.ajhg.2011.07.018Traffic
Choi, C. and Davey, M. and Schluter, C. and Pandher, P. and Fang, Y. and Foster, L.J. and Conibear, E.
DOI: 10.1111/j.1600-0854.2011.01181.xAmerican Journal of Human Genetics
Vilario-Gell, C. and Wider, C. and Ross, O.A. and Dachsel, J.C. and Kachergus, J.M. and Lincoln, S.J. and Soto-Ortolaza, A.I. and Cobb, S.A. and Wilhoite, G.J. and Bacon, J.A. and Bahareh Behrouz and Melrose, H.L. and Hentati, E. and Puschmann, A. and Evans, D.M. and Conibear, E. and Wasserman, W.W. and Aasly, J.O. and Burkhard, P.R. and Djaldetti, R. and Ghika, J. and Hentati, F. and Krygowska-Wajs, A. and Lynch, T. and Melamed, E. and Rajput, A. and Rajput, A.H. and Solida, A. and Wu, R.-M. and Uitti, R.J. and Wszolek, Z.K. and Vingerhoets, F. and Farrer, M.J.
DOI: 10.1016/j.ajhg.2011.06.001Current Opinion in Cell Biology
Conibear, E.
DOI: 10.1016/j.ceb.2010.05.009Journal of Cell Science
Conibear, E. and Davis, N.G.
DOI: 10.1242/jcs.059287Traffic
Montpetit, B. and Conibear, E.
DOI: 10.1111/j.1600-0854.2009.00895.xTrafficking Inside Cells
Elizabeth Conibear and Yuen Yi C. Tam
DOI: 10.1007/978-0-387-93877-6_4Journal of Cell Biology
Burston, H.E. and Maldonado-Bez, L. and Davey, M. and Montpetit, B. and Schluter, C. and Wendland, B. and Conibear, E.
DOI: 10.1083/jcb.200811116Molecular Biology of the Cell
Schluter, C. and Lam, K.K.Y. and Brumm, J. and Wu, B.W. and Saunders, M. and Stevens, T.H. and Bryan, J. and Conibear, E.
DOI: 10.1091/mbc.E07-07-0659Molecular Microbiology
Weissman, Z. and Shemer, R. and Conibear, E. and Kornitzer, D.
DOI: 10.1111/j.1365-2958.2008.06277.xMethods in Molecular Biology
Burston, H.E. and Davey, M. and Conibear, E.
DOI: 10.1007/978-1-59745-261-8_3PLoS ONE
Brumm, J. and Conibear, E. and Wasserman, W.W. and Bryan, J.
DOI: 10.1371/journal.pone.0003358Amyotrophic Lateral Sclerosis
Meisler, M.H. and Russ, C. and Montgomery, K.T. and Greenway, M. and Ennis, S. and Hardiman, O. and Figlewicz, D.A. and Quenneville, N.R. and Conibear, E. and Brown Jr., R.H.
DOI: 10.1080/17482960801934403Cell
Kostelansky, M.S. and Schluter, C. and Tam, Y.Y.C. and Lee, S. and Ghirlando, R. and Beach, B. and Conibear, E. and Hurley, J.H.
DOI: 10.1016/j.cell.2007.03.016Journal of Cell Biology
Lam, K.K.Y. and Davey, M. and Sun, B. and Roth, A.F. and Davis, N.G. and Conibear, E.
DOI: 10.1083/jcb.200602049Molecular Biology of the Cell
Quenneville, N.R. and Chao, T.-Y. and McCaffery, J.M. and Conibear, E.
DOI: 10.1091/mbc.E05-11-1002Traffic
Quenneville, N.R. and Conibear, E.
DOI: 10.1111/j.1600-0854.2006.00436.xMolecular Biology of the Cell
Conibear, E. and Cleck, J.N. and Stevens, T.H.
DOI: 10.1091/mbc.E02-10-0654Molecular Biology of the Cell
Kweon, Y. and Rothe, A. and Conibear, E. and Stevens, T.H.
DOI: 10.1091/mbc.E02-10-0687Methods in Enzymology
Conibear, E. and Stevens, T.H.
DOI: 10.1016/S0076-6879(02)51861-9Journal of cell science
Panek HR and Conibear E and Bryan JD and Colvin RT and Goshorn CD and Robinson LC
PubMed: 1108204712 / 2000
Journal of Cell Science
Panek, H.R. and Conibear, E. and Bryan, J.D. and Colvin, R.T. and Goshorn, C.D. and Robinson, L.C.
Molecular Biology of the Cell
Conibear, E. and Stevens, T.H.
DOI: 10.1091/mbc.11.1.305Biochimica et Biophysica Acta - Molecular Cell Research
Conibear, E. and Stevens, T.H.
DOI: 10.1016/S0167-4889(98)00058-5Cell
Conibear, E. and Stevens, T.H.
DOI: 10.1016/0092-8674(95)90088-8Journal of Cell Biology
Nothwehr, S.F. and Conibear, E. and Stevens, T.H.
DOI: 10.1083/jcb.129.1.35Journal of cell science
Conibear E and Pearse BM
PubMed: 805684604 / 1994
Journal of Cell Science
Conibear, E. and Pearse, B.M.F.
The EMBO Journal
Glickman, J. N., Conibear, E., & Pearse, B. M. (1989). Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor. The EMBO Journal, 8(4), 1041"1047.
PubMed: PMC40091204 / 1989
EMBO Journal
Glickman, J.N. and Conibear, E. and Pearse, B.M.F.
DOI: 10.1002/j.1460-2075.1989.tb03471.xVesicle traffic is regulated by factors that select cargo for incorporation into a forming vesicle and direct its docking and fusion with the appropriate target membrane. The machinery that controls transport between two intracellular compartments - the endosome and the trans-Golgi network - is of particular interest because these compartments act as relay stations, directing a large number of different sorting events. We have used a genetic approach in the yeast model system to identify four components of a conserved protein complex (GARP: Golgi-associated retrograde protein complex) that directs the targeting of transport vesicles with the trans-Golgi network. We are currently using genetic, cell biological and biochemical techniques to analyze the interactions that link this vesicle targeting complex to other components of the membrane fusion machinery.
Recent advances in genome-wide phenotypic screening in yeast, combined with powerful bioinformatics analyses, hold great promise for the rapid and comprehensive identification of novel multi-subunit complexes. Functional genomics is expected to uncover most of the genes required for the trafficking of proteins and lipids through Golgi and endosomal compartments. In genome-wide screens, we have identified sets of genes likely to act together at common regulatory steps in protein sorting. We are now using biochemical/cell biological assays to characterize interacting proteins and analyze their role in protein and lipid trafficking in detail. Tackling a problem at many different levels - from genome-wide discovery studies in yeast, to the biochemical and cell biological characterization of specific protein complexes, to the investigation of homologous proteins in mammalian cells - allows an in-depth analysis of protein function and ensures that discoveries made in a simple model organism are efficiently translated to the study of medically relevant processes in mammalian cells.
Canada Foundation for Innovation Grant, 2013
UBC Killam Teaching Prize, 2014
Every day, our researchers work towards breakthroughs to transform the lives of kids in BC and around the world. Learn about our latest innovations and advancements in child health.

Congratulations to the BC Children's Hospital Research Institute (BCCHR) and Women’s Health Research Institute (WHRI) investigators and their teams who were awarded funding through the Canadian Institutes of Health Research (CIHR) Fall 2021 Project Grant competition. Our research community received around $6 million in new research grants as principal investigators or co-investigators.
BC Children’s Hospital is pleased to congratulate the recipients of the 2020 BCCHR Studentships and Fellowships.
BC Children's Hospital Research Institute is pleased to congratulate the recipients of the 2019 Outstanding Achievement Awards and the 2019 BCCHR Studentships and Fellowships.
At BC Children’s, we are making discoveries that save lives and transform health care for children in our province and around the world. Our research portfolio includes basic, clinical, population, and public health research.
EXPLORE OUR RESEARCH
Sign up for compelling stories about innovative science, the doctors and researchers who turn ideas into discoveries and treatments, and the kids and families whose lives are changed.