Overview

My research program is comprised of projects to describe patterns and outcomes of critical illness among children living in remote and resource-limited places in British Columbia and across the world. My aim is to understand the infrastructure of healthcare for critically ill children in settings where high-cost, high-technology, and specialized care are less readily available and to evaluate strategies to improve the quality of care in these settings.

Publications

Amplifying voices: providing quality critical care to Canada’s remote and rural children during pediatric transport
Canadian Journal of Emergency Medicine
Katie O’Hearn and Samir Shaheen-Hussain and Fiona Muttalib
DOI: 10.1007/s43678-022-00300-5
04/2022

Cost-effectiveness analysis of implementing an integrated neonatal care kit to reduce neonatal infection in rural Pakistan
BMJ Open
Fiona Muttalib and Karen Chung and Lisa Grace Pell and Shabina Ariff and Sajid Soofi and Shaun K Morris and Beate Sander
DOI: 10.1136/bmjopen-2020-047793
01/2022

Application of systems dynamics and group model building to identify barriers and facilitators to acute care delivery in a resource limited setting
BMC Health Services Research
Fiona Muttalib and Ellis Ballard and Josephine Langton and Sara Malone and Yudy Fonseca and Andreas Hansmann and Kenneth Remy and Peter Hovmand and Allan Doctor
DOI: 10.1186/s12913-020-06014-7
12/2021

Pediatric Emergency and Critical Care Resources and Infrastructure in Resource-Limited Settings: A Multicountry Survey*
Critical Care Medicine
Muttalib, F. and Gonz{\'a}lez-Dambrauskas, S. and Lee, J.H. and Steere, M. and Agulnik, A. and Murthy, S. and Adhikari, N.K.J.
DOI: 10.1097/CCM.0000000000004769
2021

Risk of dispersion or aerosol generation and infection transmission with nasopharyngeal and oropharyngeal swabs for detection of COVID-19: A systematic review
BMJ Open
Agarwal, A. and Fernando, S.M. and Honarmand, K. and Bakaa, L. and Brar, S. and Granton, D. and Chaudhuri, D. and Chetan, D. and Hu, M. and Basmaji, J. and Muttalib, F. and Rochwerg, B. and Adhikari, N.K.J. and Lamontagne, F. and Murthy, S. and Hui, D.S. and Gomersall, C.D. and Mubareka, S. and Diaz, J. and Burns, K.E.A. and Couban, R. and Vandvik, P.O.
DOI: 10.1136/bmjopen-2020-040616
2021

Hospital outcomes of children admitted to intensive care in British Columbia via interfacility transfer versus direct admission from 2015 to 2017: a descriptive analysis
CMAJ open
Fung, J.S.T. and Wong, S. and Murthy, S. and Muttalib, F.
DOI: 10.9778/cmajo.20200263
2021

Clinical characteristics, treatment and outcomes of paediatric COVID-19: A systematic review and meta-analysis
Archives of Disease in Childhood
Irfan, O. and Muttalib, F. and Tang, K. and Jiang, L. and Lassi, Z.S. and Bhutta, Z.
DOI: 10.1136/archdischild-2020-321385
2021

High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission,Les canules nasales à haut débit pour le traitement de l’insuffisance respiratoire hypoxémique aiguë chez les patients atteints de la COVID-19: comptes rendus systématiques de l’efficacité et des risqu
Canadian Journal of Anesthesia
Agarwal, A. and Basmaji, J. and Muttalib, F. and Granton, D. and Chaudhuri, D. and Chetan, D. and Hu, M. and Fernando, S.M. and Honarmand, K. and Bakaa, L. and Brar, S. and Rochwerg, B. and Adhikari, N.K. and Lamontagne, F. and Murthy, S. and Hui, D.S.C. and Gomersall, C. and Mubareka, S. and Diaz, J.V. and Burns, K.E.A. and Couban, R. and Ibrahim, Q. and Guyatt, G.H. and Vandvik, P.O.
DOI: 10.1007/s12630-020-01740-2
2020

Performance of Pediatric Mortality Prediction Models in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis
Journal of Pediatrics
Muttalib, F. and Clavel, V. and Yaeger, L.H. and Shah, V. and Adhikari, N.K.J.
DOI: 10.1016/j.jpeds.2020.05.016
2020

Psychological Consequences of Admission to the ICU: Helping Patients and Families
JAMA - Journal of the American Medical Association
Rose, L. and Muttalib, F. and Adhikari, N.K.J.
DOI: 10.1001/jama.2019.9059
2019

How to push the limit: Developing informed research and implementation programs in resource-limited settings
Pediatric Critical Care Medicine
Muttalib, F. and Doctor, A.
DOI: 10.1097/PCC.0000000000001565
2018

The gap between coverage and care-what can Canadian paediatricians do about access to health services for refugee claimant children?
Paediatrics and Child Health (Canada)
Rink, N. and Muttalib, F. and Morantz, G. and Chase, L. and Cleveland, J. and Rousseau, C. and Li, P.
DOI: 10.1093/pch/pxx115
2017

Absence of pleocytosis alone is insufficient to exclude encephalitis caused by herpes simplex virus in children
Journal of Clinical Microbiology
Muttalib, F. and Papenburg, J.
DOI: 10.1128/JCM.03262-13
2014

Research

Infrastructure of Pediatric Emergency and Critical Care in Resource-Limited Settings
The aim of this study is to describe global infrastructure for the care of critically ill children in resource-limited settings through a multi-national research collaboration. We will explore regional differences in structural, human, and material resources for emergency and critical care with particular focus on global regions with the highest burden of preventable child mortality.

Predictors of Mortality among Children and Young Adolescents Hospitalized in Low- and Middle-Income Countries
To date, school-age children and early adolescents have been relatively neglected in global health literature due to perceived lower risk of death. Recent estimates suggest that there remains a significant burden of preventable mortality among these children. The aim of this research is to describe the epidemiology of critical illness among children and early adolescents across the age spectrum (including age 5 – 14 years) and to identify early predictors of hospital mortality. We will explore cause of illness among older children and validate/update existing prognostic models for hospital and early post-discharge mortality in these older age groups.

Honours & Awards

Canadian Institutes for Health Research Frederick Banting and Charles Best Canada Graduate Scholarship Doctoral Award