My research interests are diverse but focused. I have a firm interest in bone tumors and a soft spot for soft tissue sarcomas, including understanding the underlying pathophysiology and translational work in the clinical pathology lab setting. I joined the 2019-2021 cohort within the Children’s Oncology Group Young Investigator Program with a focus in the bone tumor group. I also am interested in exploring cell signaling and cell-to-cell communication through conventional molecular and proteomic analysis with fellow investigators. My second area of research interest is in gastrointestinal pathology, particularly eosinophilic esophagitis (EoE). Through these EoE projects, I enjoyed expanding my experience in immunology which builds on an interest during my fellowship at Lurie Children’s Hospital of Chicago, which explored transplant immunology and the effect on the gastrointestinal tract. I also enjoy expanding my experience in the area of transplant immunology. My last primary area of interest is in developmental pathology, which often stems from identifying common pathologic findings in the interesting cases I encounter at BC Children’s and Women’s Hospital. I have an interest in leadership and administration, which blossomed during my time as Cohort 2 in the BC Patient Safety and Quality Council’s Clinician Quality Academy.


Quantifying Proximal Collecting Tubule Deficiency in Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Fetopathy
Pediatric and Developmental Pathology
Jessica Saunders and Allison Marie Callejas Salgado and Joseph Y Ting and Cherry Mammen and Jefferson Terry and Jonathan W Bush
DOI: 10.1177/10935266211018922

SMARCA4 -deficient rhabdoid tumours show intermediate molecular features between SMARCB1 -deficient rhabdoid tumours and small cell carcinomas of the ovary, hypercalcaemic type
The Journal of Pathology
Mamy Andrianteranagna and Joanna Cyrta and Julien Masliah-Planchon and Karolina Nemes and Alice Corsia and Amaury Leruste and Dörthe Holdhof and Uwe Kordes and Daniel Orbach and Nadège Corradini and Natacha Entz-Werle and Gaëlle Pierron and Marie-Pierre Castex and Anne Brouchet and Noëlle Weingertner and Dominique Ranchère and Paul Fréneaux and Olivier Delattre and Jonathan Bush and Alexandra Leary and Michael C. Frühwald and Ulrich Schüller and Nicolas Servant and Franck Bourdeaut
DOI: 10.1002/path.5705

Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases
Acta Neuropathologica
Dörthe Holdhof and Pascal D. Johann and Michael Spohn and Michael Bockmayr and Sepehr Safaei and Piyush Joshi and Julien Masliah-Planchon and Ben Ho and Mamy Andrianteranagna and Franck Bourdeaut and Annie Huang and Marcel Kool and Santhosh A. Upadhyaya and Anne E. Bendel and Daniela Indenbirken and William D. Foulkes and Jonathan W. Bush and David Creytens and Uwe Kordes and Michael C. Frühwald and Martin Hasselblatt and Ulrich Schüller
DOI: 10.1007/s00401-020-02250-7

Poor Correlation of Oral Swabs with Esophageal Eosinophil Counts.
Avinashi V and Chan JM and Bush JW and Vallance BA and Yang H and Portales-Casamar E and Soller L and Mill C and Chan ES
DOI: 10.1007/s00455-019-10082-1
PubMed: 31773332

Spindle Epithelial Tumor with Thymus-Like Differentiation (SETTLE): A Case Report
Fetal and Pediatric Pathology
Cyrus L Matheson and Geoffrey K Blair and Jonathan Bush
DOI: 10.1080/15513815.2019.1600625

Novel Exonic Deletions in TTC7A in a Newborn with Multiple Intestinal Atresia and Combined Immunodeficiency
Journal of Clinical Immunology
Jessica R. Saunders and Anna Lehman and Stuart E. Turvey and Jie Pan and Evica Rajcan-Separovic and Aleixo M. Muise and Jonathan W. Bush
DOI: 10.1007/s10875-019-00669-6

Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in T regulatory cells
JCI Insight
DOI: 10.1172/jci.insight.123672

Pediatric Pathology Fellowship Recruitment—Report of a Survey Conducted by the Fellowship Committee of the Society for Pediatric Pathology
Pediatric and Developmental Pathology
Singh, V. and Eldin, K. and Timmons, C. and Bush, J. and Rabah, R.
DOI: 10.1177/1093526617722905

Pediatric Eosinophilic Esophagitis Is Associated With Increased Lamina Propria Immunoglobulin G4-Positive Plasma Cells
Journal of pediatric gastroenterology and nutrition
DOI: 10.1097/mpg.0000000000001949

Eosinophilic density in graft biopsies positive for rejection and blood eosinophil count can predict development of post-transplant digestive tract eosinophilia
Pediatric Transplantation
Bush, J.W. and Mohammad, S. and Melin-Aldana, H. and Kagalwalla, A.F. and Arva, N.C.
DOI: 10.1111/petr.12693

Treatment of neuroblastoma in congenital central hypoventilation syndrome with a PHOX2B polyalanine repeat expansion mutation: New twist on a neurocristopathy syndrome
Pediatric Blood and Cancer
Armstrong, A.E. and Weese-Mayer, D.E. and Mian, A. and Maris, J.M. and Batra, V. and Gosiengfiao, Y. and Reichek, J. and Madonna, M.B. and Bush, J.W. and Shore, R.M. and Walterhouse, D.O.
DOI: 10.1002/pbc.25572

Combined robotic and open approach to excision of accessory bladder and urethral triplication
Journal of Pediatric Urology
Bowen, D.K. and Glaser, A.P. and Bush, J.W. and Cheng, E.Y. and Gong, E.M.
DOI: 10.1016/j.jpurol.2014.11.009

Deconstructing the diagnosis of hemophagocytic lymphohistiocytosis using illustrative cases
Journal of Hematopathology
Weinstein, J.L. and Badawy, S.M. and Bush, J.W. and Schafernak, K.T.
DOI: 10.1007/s12308-015-0254-3

Intracranial atypical teratoid/rhabdoid tumor presenting as an axillary mass: A case report and review of literature
Pediatric and Developmental Pathology
Bush, J.W. and Hancock, B.J. and Israels, S.J. and Ellison, D.W. and Stefanovici, C. and Krawitz, S.
DOI: 10.2350/14-01-1427-CR.1

Outcomes of persons with blastomycosis involving the central nervous system
Diagnostic Microbiology and Infectious Disease
Bush, J.W. and Wuerz, T. and Embil, J.M. and Del Bigio, M.R. and McDonald, P.J. and Krawitz, S.
DOI: 10.1016/j.diagmicrobio.2013.03.002


Eosinophilic Esophagitis including the role of IgG4 and other biomarkers

Sarcoma including the role of SWI/SNF proteins

Osteosarcoma including the role of activated beta-catenin

Research Group Members

Michelle Dittrick, Clinical Research Program Manager