Dr. Chanoine is a Pediatrician who graduated from Belgium in 1982. He joined the University of British Columbia in 1998 as Clinical Professor and Head of the Endocrinology and Diabetes Unit at BC Children’s Hospital. His previous experience includes a fellowship at the University of Massachusetts Medical Center in Worcester, USA; Pediatric Endocrinologist at Hôpital des Enfants Reine Fabiola in Brussels; and Medical Director for Novo Nordisk Belgium.

He is increasingly active in Global Health projects in the field of Pediatric Endocrinology and Diabetes in resource-constrained settings. Dr Chanoine is presently Secretary General of Global Pediatric Endocrinology and Diabetes (www.globalpedendo.org), an international non-profit organization that aims at promoting Pediatric Endocrine care in low income countries.

Dr Chanoine’s research is also focusing on the management of childhood overweight. Dr Chanoine is principal investigator of “Healthy Buddies”, a peer-led curriculum aiming at preventing the development of overweight in elementary school children and initiated the LiGHT project (Living Green, Healthy and Thrifty).

Trainees interested in Global Health (Non Communicable Diseases) are welcome to contact Dr Chanoine for potential projects.


Development of a Multilingual Global e-learning Curriculum in Pediatric Endocrinology and Diabetes for Front Line Health Care Providers in Resource-Limited Countries (Preprint)
Evangelia Kalaitzoglou and Edna Majaliwa and Margaret Zacharin and Carine de Beaufort and Jean-Pierre Chanoine and Conny van Wijngaard-DeVugt and Ervin Sperla and Annemieke M. Boot and Stenvert L.S. Drop
DOI: 10.2196/preprints.18555

Adrenal function following acute discontinuation of glucocorticoids in children with acute lymphocytic leukemia: A prospective study
Pediatric Hematology and Oncology
Noman Ahmad and Ibraheem Faisal Abosoudah and Mrouge Mohamed Sobaihi and Ali Hassan Algiraigri and Farh Roujouleh and Fatima Ghurab and Jean-Pierre Chanoine
DOI: 10.1080/08880018.2019.1652710

Incidence of disorders of sexual development in neonates in Ghana: prospective study
Archives of Disease in Childhood
Emmanuel Ameyaw and Serwah Bonsu Asafo-Agyei and Ieuan A Hughes and Margaret Zacharin and Jean-Pierre Chanoine
DOI: 10.1136/archdischild-2019-316986

Normative data on penile and anogenital measurements of term male infants in Sagamu, Nigeria.
Acta paediatrica (Oslo, Norway : 1992)
Adekoya AO and Fetuga MB and Jarrett OO and Ogunlesi TA and Chanoine JP and Oba-Daini OO
DOI: 10.1111/apa.14885
PubMed: 31162733

Is Age a Risk Factor for Cerebral Edema in Children With Diabetic Ketoacidosis? A Literature Review.
Canadian journal of diabetes
Glackin S and Metzger D and Hanas R and Chanoine JP
DOI: 10.1016/j.jcjd.2019.04.013
PubMed: 31311730

Continued attendance for paediatric weight management: A multicentre, qualitative study of parents' reasons and facilitators.
Clinical obesity
Farnesi BC and Perez A and Holt NL and Morrison KM and Gokiert R and Legault L and Chanoine JP and Sharma AM and Ball GDC
DOI: 10.1111/cob.12304
PubMed: 30775853

Pathways to eating in children and adolescents with obesity.
International journal of obesity (2005)
Clairman H and Dettmer E and Buchholz A and Cordeiro K and Ibrahim Q and Maximova K and Toulany A and Taylor VH and Katzman DK and Morrison KM and Hamilton J and Zenlea I
DOI: 10.1038/s41366-018-0271-2
PubMed: 30568266

Insights from the WHO and National Lists of Essential Medicines: Focus on Pediatric Diabetes Care in Africa
Hormone Research in Paediatrics
Amanda Rowlands and Emmanuel Ameyaw and Florent Rutagarama and Joel Dipesalema and Edna Siima Majaliwa and Joyce Mbogo and Graham D. Ogle and Jean-Pierre Chanoine
DOI: 10.1159/000490467

Growth hormone treatment of Canadian children: results from the GeNeSIS phase IV prospective observational study.
CMAJ open
Deal C and Kirsch S and Chanoine JP and Lawrence S and Cummings E and Rosolowsky ET and Marks SD and Jia N and Child CJ and GeNeSIS National Board on behalf of the GeNeSIS Canada Investigators
DOI: 10.9778/cmajo.20180020
PubMed: 30201821

The CANadian Pediatric Weight management Registry (CANPWR): lessons learned from developing and initiating a national, multi-centre study embedded in pediatric clinical practice.
BMC pediatrics
Morrison KM and Ball GDC and Ho J and Mackie P and Buchholz A and Chanoine JP and Hamilton J and Laberge AM and Legault L and Thabane L and Tremblay M and Zenlea I
DOI: 10.1186/s12887-018-1208-6
PubMed: 30025530

CHIPS-Child: Testing the developmental programming hypothesis in the offspring of the CHIPS trial.
Pregnancy hypertension
Magee LA and Synnes AR and von Dadelszen P and Hutfield AM and Chanoine JP and Côté AM and Devlin AM and Dorling J and Gafni A and Ganzevoort W and Helewa ME and Hutton EK and Koren G and CHIPS-Child Study Group (Table S1)
DOI: 10.1016/j.preghy.2018.04.021
PubMed: 30527103

A Multi-Week Assessment of a Mobile Exergame Intervention in an Elementary School.
Games for health journal
Garde A and Chowdhury M and Rollinson AU and Johnson M and Prescod P and Chanoine JP and Ansermino JM and Dumont GA
DOI: 10.1089/g4h.2017.0023
PubMed: 29394109

Parent Recommendations to Enhance Enrollment in Multidisciplinary Clinical Care for Pediatric Weight Management.
The Journal of pediatrics
Perez AJ and Kebbe M and Holt NL and Gokiert R and Chanoine JP and Legault L and Morrison KM and Sharma AM and Ball GDC
DOI: 10.1016/j.jpeds.2017.09.025
PubMed: 29246332

Central adrenal insufficiency following traumatic brain injury: a missed diagnosis in the critically injured.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
DOI: 10.1007/s00381-017-3536-5
PubMed: 28721596

Consanguineous Marriages and Endocrine Diseases in Arab Societies.
Pediatric endocrinology reviews : PER
Ahmad N and Chanoine JP
DOI: 10.17458/per.vol15.2017.ach.consanguineousmarriagesendocrine
PubMed: 29292627

Anogenital Distance in Term Newborns in Kumasi, Ghana
Hormone Research in Paediatrics
Serwah Bonsu Asafo-Agyei and Emmanuel Ameyaw and Jean-Pierre Chanoine and Margaret Zacharin and Samuel Blay Nguah and Olumide Olatokunbo Jarrett
DOI: 10.1159/000479689

Global Health for the Paediatric Endocrinologist
K Ong and Z Hochberg eds, Yearbook of Paediatric Endocrinology 2017

Clitoral size in term newborns in Kumasi, Ghana
International Journal of Pediatric Endocrinology
Serwah Bonsu Asafo-Agyei and Emmanuel Ameyaw and Jean-Pierre Chanoine and Margaret Zacharin and Samuel Blay Nguah
DOI: 10.1186/s13633-017-0045-y

Does parental and adolescent participation in an e-health lifestyle modification intervention improve weight outcomes?
BMC Public Health
Andrew W. Tu and Allison W. Watts and Jean-Pierre Chanoine and Constadina Panagiotopoulos and Josie Geller and Rollin Brant and Susan I. Barr and Louise Mâsse
DOI: 10.1186/s12889-017-4220-0

Normative penile anthropometry in term newborns in Kumasi, Ghana: a cross-sectional prospective study
International Journal of Pediatric Endocrinology
Serwah Bonsu Asafo-Agyei and Emmanuel Ameyaw and Jean-Pierre Chanoine and Samuel Blay Nguah
DOI: 10.1186/s13633-017-0042-1

Assessing resting energy expenditure in overweight and obese adolescents in a clinical setting: validity of a handheld indirect calorimeter.
Pediatric research
DOI: 10.1038/pr.2016.182
PubMed: 27653085

Global Application of the Assessment of Communication Skills of Paediatric Endocrinology Fellows in the Management of Differences in Sex Development Using the ESPE E-Learning.Org Portal.
Hormone research in paediatrics
DOI: 10.1159/000475992
PubMed: 28689203

Child and Adolescent Obesity
Pediatric Endocrinology and Inborn Errors of Metabolism

Why do parents discontinue health services for managing paediatric obesity? A multi-centre, qualitative study.
Obesity research & clinical practice
DOI: 10.1016/j.orcp.2016.10.285
PubMed: 27789201

Ghrelin, Ghrelin O-Acyltransferase, and Carbohydrate Metabolism During Pregnancy in Calorie-Restricted Mice
Hormone and Metabolic Research
Arjun Trivedi and Sandra Babic and Mark Heiman and William Gibson and Jean-Pierre Chanoine
DOI: 10.1055/s-0042-116117

WHO and national lists of essential medicines in Mexico, Central and South America, and the Caribbean: are they adequate to promote paediatric endocrinology and diabetes care?
BMJ Global Health
Amanda Rowlands and Alejandra Acosta-Gualandri and Jaime Guevara-Aguirre and Jean-Pierre Chanoine
DOI: 10.1136/bmjgh-2016-000114

Global Health for the Paediatric Endocrinologist
K Ong and Z Hochberg eds, Yearbook of Paediatric Endocrinology 2016

Recommendations From Parents to Improve Health Services for Managing Pediatric Obesity in Canada.
Academic pediatrics
DOI: 10.1016/j.acap.2016.05.144
PubMed: 27236018

Evaluation of a Novel Mobile Exergame in a School-Based Environment.
Cyberpsychology, behavior and social networking
DOI: 10.1089/cyber.2015.0281
PubMed: 26882222

Why do families enrol in paediatric weight management? A parental perspective of reasons and facilitators.
Child: care, health and development
DOI: 10.1111/cch.12311
PubMed: 26728419

The Edmonton Obesity Staging System for Pediatrics: A proposed clinical staging system for paediatric obesity
Paediatrics & Child Health
Stasia Hadjiyannakis and Annick Buchholz and Jean-Pierre Chanoine and Mary M Jetha and Laurie Gaboury and Jill Hamilton and Catherine Birken and Katherine M Morrison and Laurent Legault and Tracey Bridger and Stephen R Cook and John Lyons and Arya M Sharma and Geoff DC Ball
DOI: 10.1093/pch/21.1.21

Cardiac Autonomic Function at Baseline and under Stress and Its Relationship to Circulatory Markers of Inflammation in Obese Compared to Nonobese Children: A Pilot Study.
Hormone research in paediatrics
DOI: 10.1159/000445685
PubMed: 27105080

Conserved Telomere Length in Human Ectopic Thyroids: An Argument Against Premature Differentiation Causing Arrested Migration
Stéphanie Larrivée-Vanier and Fabien Magne and Natalie Patey and Jean-Pierre Chanoine and Jean-Marc Vuissoz and Guy Van Vliet and Johnny Deladoëy
DOI: 10.1089/thy.2015.0204

Individual and household predictors of adolescents' adherence to a web-based intervention.
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
DOI: 10.1007/s12160-014-9658-z
PubMed: 25270826

Use of growth charts in Canada: A National Canadian Paediatric Surveillance Program survey.
Paediatrics & child health
DOI: 10.1093/pch/20.4.185
PubMed: 26038634

Why don't families initiate treatment? A qualitative multicentre study investigating parents' reasons for declining paediatric weight management.
Paediatrics & child health
DOI: 10.1093/pch/20.4.179
PubMed: 26038633

Assessment of a Mobile Game ("MobileKids Monster Manor") to Promote Physical Activity Among Children.
Games for health journal
DOI: 10.1089/g4h.2014.0095
PubMed: 26181809

Alternating hypoglycemia and hyperglycemia in a toddler with a homozygous p.R1419H ABCC8 mutation: an unusual clinical picture.
Journal of pediatric endocrinology & metabolism : JPEM
DOI: 10.1515/jpem-2014-0265
PubMed: 25720052

Acylated ghrelin is not required for the surge in pituitary growth hormone observed in pregnant mice.
DOI: 10.1016/j.peptides.2015.01.005
PubMed: 25645493

Developing and Pilot Testing the Readiness and Motivation Interview for Families in Pediatric Weight Management
Canadian Journal of Dietetic Practice and Research
Josie Geller and Jillian Avis and Suja Srikameswaran and Joanna Zelichowska and Katie Dartnell and Bailey Scheuerman and Arnaldo Perez and Allison Rasquinha and Krista E. Brown and Jean-Pierre Chanoine and Geoff Ball
DOI: 10.3148/cjdpr-2015-024

Canadian Pediatric Weight Management Registry (CANPWR): baseline descriptive statistics and comparison to Canadian norms.
BMC obesity
DOI: 10.1186/s40608-015-0060-6
PubMed: 26417450

Beyond Weight Loss: Experiences and Insights Related to Working Effectively with Families and Operating within the Health Care System to Manage Pediatric Obesity
Metabolic Syndrome and Obesity in Childhood and Adolescence
Geoff D.C. Ball and Jillian L.S. Avis and Annick Buchholz and Tracey Bridger and Jean-Pierre Chanoine and Stasia Hadjiyannakis and Jill K. Hamilton and Laurent Legault and Katherine M. Morrison and Anne Wareham and Mary M. Jetha
DOI: 10.1159/000368136

How can we keep children and families motivated for weight management?
Canadian Journal of Diabetes (Special Primary Care Edition)

Role for Tissue-Dependent Methylation Differences in the Expression of FOXE1 in Nontumoral Thyroid Glands
The Journal of Clinical Endocrinology & Metabolism
Rasha Abu-Khudir and Fabien Magne and Jean-Pierre Chanoine and Cheri Deal and Guy Van Vliet and Johnny Deladoëy
DOI: 10.1210/jc.2013-4414

Quetiapine treatment in youth is associated with decreased insulin secretion.
Journal of clinical psychopharmacology
DOI: 10.1097/jcp.0000000000000118
PubMed: 24633003

The CANadian Pediatric Weight management Registry (CANPWR): study protocol.
BMC pediatrics
DOI: 10.1186/1471-2431-14-161
PubMed: 24957705

Effectiveness of peer-based healthy living lesson plans on anthropometric measures and physical activity in elementary school students: a cluster randomized trial.
JAMA pediatrics
DOI: 10.1001/jamapediatrics.2013.3688
PubMed: 24515353

It’s like rocket science…only more complex: challenges and experiences related to managing pediatric obesity in Canada
Expert Review of Endocrinology & Metabolism
Jillian LS Avis and Tracey Bridger and Annick Buchholz and Jean-Pierre Chanoine and Stasia Hadjiyannakis and Jill Hamilton and Mary M Jetha and Laurent Legault and Katherine M Morrison and Anne Wareham and Geoff DC Ball
DOI: 10.1586/17446651.2014.897605

Baseline Measures of Participants in the Canadian Pediatric Weight Management Registry (CANPWR) Pilot Study
Obesity Reviews

Weight management in Canada: an environmental scan of health services for adults with obesity
BMC Health Services Research
Marie-Michèle Rosa Fortin and Christine Brown and Geoff DC Ball and Jean-Pierre Chanoine and Marie-France Langlois
DOI: 10.1186/1472-6963-14-69

Extending World Health Organization weight-for-age reference curves to older children
BMC Pediatrics
Celia Rodd and the Canadian Pediatric Endocrine Group (CPEG) Working Committee for National Growth Charts and Daniel L Metzger and Atul Sharma
DOI: 10.1186/1471-2431-14-32

Abnormal Blood Glucose as a Prognostic Factor for Adverse Clinical Outcome in Children Admitted to the Paediatric Emergency Unit at Komfo Anokye Teaching Hospital, Kumasi, Ghana
International Journal of Pediatrics
Emmanuel Ameyaw and Kwame Amponsah-Achiano and Peter Yamoah and Jean-Pierre Chanoine
DOI: 10.1155/2014/149070

Overcoming obesity and unhealthy weight in children and youth in BC
BC Medical Journal

Role of Ghrelin and GH in Maintaining Glucose Homeostasis in Pregnant Mice During Calorie Restriction
Canadian Journal of Diabetes
Arjun Trivedi and William Gibson and Sandra Babich and Jean-Pierre Chanoine
DOI: 10.1016/j.jcjd.2013.08.069

Thyroid Function from Birth to Adolescence in Prader-Willi Syndrome
The Journal of Pediatrics
Mohamad Sharkia and Stéphanie Michaud and Marie-Thérèse Berthier and Yves Giguère and Laura Stewart and Johnny Deladoëy and Cheri Deal and Guy Van Vliet and Jean-Pierre Chanoine
DOI: 10.1016/j.jpeds.2013.03.058

Canadian Pediatric Endocrine Group extension to WHO growth charts: Why bother?
Paediatrics & child health
PubMed: 24421695

Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.
American journal of human genetics
DOI: 10.1016/j.ajhg.2013.04.008
PubMed: 23643382

Process Evaluation of the Living Green, Healthy and Thrifty (LiGHT) Web-Based Child Obesity Management Program: Combining Health Promotion with Ecology and Economy
Canadian Journal of Diabetes
Maria Jogova and Joshua Eun-Soo Song and Audrey Clare Campbell and Darren Warbuton and Tom Warshawski and Jean-Pierre Chanoine
DOI: 10.1016/j.jcjd.2013.03.359

Promoting Excellence in the Care of Pediatric Endocrine Diseases in the Developing World
M. Zacharin and J. P. Chanoine and F. Cassorla and S. Brink and R. Hanas and H. L. Fideleff and A. Oduwole and N. Shah and Z. Hochberg and on behalf of all 70 Global Pediatric Endocrinology and Diabetes Active Members
DOI: 10.1542/peds.2012-0848

Healthy Buddies© Manitoba: A Clustered Randomized Controlled Trial of Peer-Based Healthy Living Lessons Plans on Body Weight and Physical Activity in Early Years Students
Canadian Journal of Diabetes
Rob Santos and Anita Durksen and Jean Pierre Chanoine and Andrea Lamboo Miln and Theresa Mayer and Jonathan Mcgavock
DOI: 10.1016/j.jcjd.2012.07.083

Evidence for Calcitonin-Producing Cells in Human Lingual Thyroids
The Journal of Clinical Endocrinology & Metabolism
Isabelle Vandernoot and Hervé Sartelet and Rasha Abu-Khudir and Jean-Pierre Chanoine and Johnny Deladoëy
DOI: 10.1210/jc.2011-2772

Pitfalls in the determination of human acylated ghrelin plasma concentrations using a double antibody enzyme immunometric assay
Clinical Biochemistry
Arjun Trivedi and Sandra Babic and Jean-Pierre Chanoine
DOI: 10.1016/j.clinbiochem.2011.10.023

Should I stay or should I go? Understanding families’ decisions regarding initiating, continuing, and terminating health services for managing pediatric obesity: the protocol for a multi-center, qualitative study
BMC Health Services Research
Geoff DC Ball and Arnaldo Perez Garcia and Jean-Pierre Chanoine and Katherine M Morrison and Laurent Legault and Arya M Sharma and Rebecca Gokiert and Nicholas L Holt
DOI: 10.1186/1472-6963-12-486

GnRH-deficient phenotypes in humans and mice with heterozygous variants in KISS1/Kiss1.
The Journal of clinical endocrinology and metabolism
DOI: 10.1210/jc.2011-0518
PubMed: 21880801

Obesity and physical activity in children.
Canadian family physician Medecin de famille canadien
PubMed: 21753100

Pediatric weight management programs in Canada: Where, What and How?
International Journal of Pediatric Obesity
Geoff D. C. Ball and Kathryn A. Ambler and Jean-Pierre Chanoine
DOI: 10.3109/17477166.2010.512390

Early weight loss and outcome at one year in obese adolescents treated with orlistat or placebo
International Journal of Pediatric Obesity
Jean-Pierre Chanoine and Matthew Richard
DOI: 10.3109/17477166.2010.519387

The Centre for Healthy Weights—Shapedown BC: A Family-Centered, Multidisciplinary Program that Reduces Weight Gain in Obese Children over the Short-Term
International Journal of Environmental Research and Public Health
Constadina Panagiotopoulos and Rebecca Ronsley and Mohammed Al-Dubayee and Rollin Brant and Boris Kuzeljevic and Erin Rurak and Arlene Cristall and Glynis Marks and Penny Sneddon and Mary Hinchliffe and Jean-Pierre Chanoine and Louise C. Mâsse
DOI: 10.3390/ijerph8124662

Transcriptome, Methylome and Genomic Variations Analysis of Ectopic Thyroid Glands
Rasha Abu-Khudir and Jean Paquette and Anne Lefort and Frederick Libert and Jean-Pierre Chanoine and Gilbert Vassart and Johnny Deladoëy
DOI: 10.1371/journal.pone.0013420

In Vitro and In Vivo Effect of Acylated and Unacylated Ghrelin on Neonatal Glucose Homeostasis
Pediatric Research
Hehong Ni and Kathleen De Waele and Pallavi Walia and Jean-Pierre Chanoine
DOI: 10.1203/pdr.0b013e3181da463a

Effects of glucose and insulin on acyl ghrelin and desacyl ghrelin, leptin, and adiponectin in pregnant women with diabetes
William Gibson and Jianhua Liu and Bruce Gaylinn and Michael O. Thorner and Graydon S. Meneilly and Sandra L. Babich and David Thompson and Jean-Pierre Chanoine
DOI: 10.1016/j.metabol.2009.09.033

Ontogeny of acylated ghrelin degradation in the rat
Hehong Ni and Pallavi Walia and Jean-Pierre Chanoine
DOI: 10.1016/j.peptides.2009.11.016

Pharmacotherapy and Weight-Loss Supplements for Treatment of Paediatric Obesity
Alexander L. Rogovik and Jean-Pierre Chanoine and Ran D. Goldman
DOI: 10.2165/11319210-000000000-00000

Promoting optimal monitoring of child growth in Canada: using the new WHO growth charts.
Canadian journal of dietetic practice and research : a publication of Dietitians of Canada = Revue canadienne de la pratique et de la recherche en dietetique : une publication des Dietetistes du Canada
DOI: 10.3148/71.1.2010.54
PubMed: 21815309

Body mass index in children with Prader-Willi Syndrome during human growth hormone therapy: A real world situation
The Journal of Pediatrics
Tammie Dewan and Jean-Pierre Chanoine
DOI: 10.1016/j.jpeds.2008.12.033

Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase.
American journal of physiology. Endocrinology and metabolism
DOI: 10.1152/ajpendo.90866.2008
PubMed: 19240252

Ghrelin and the growth hormone secretagogue receptor in growth and development.
International Journal of Obesity (2005)
DOI: 10.1038/ijo.2009.17
PubMed: 19363508

Efficacy, safety and tolerability of orlistat, a lipase inhibitor, in the treatment of adolescent weight excess
Roberto Bogarin and Jean-Pierre Chanoine
DOI: 10.2217/14750708.6.1.23

Ontogeny of Ghrelin, Obestatin, Preproghrelin, and Prohormone Convertases in Rat Pancreas and Stomach
Pediatric Research
Pallavi Walia and Ali Asadi and Timothy J Kieffer and James D Johnson and Jean-Pierre Chanoine
DOI: 10.1203/pdr.0b013e31818bc134

Fighting Child and Adolescent Obesity: Working Towards National, Integrated Strategies
Canadian Journal of Diabetes
Jean-Pierre Chanoine and Geoff D.C. Ball and Kathryn Hagedorn and Katherine Morrison
DOI: 10.1016/s1499-2671(09)31004-7

Long-acting octreotide treatment causes a sustained decrease in ghrelin concentrations but does not affect weight, behaviour and appetite in subjects with Prader-Willi syndrome.
European journal of endocrinology
DOI: 10.1530/eje-08-0462
PubMed: 18603572

GLP-1 and Appetite Responses to a Meal in Lean and Overweight Adolescents Following Exercise
Jean-Pierre Chanoine and Kerry J Mackelvie and Susan I Barr and Alfred C.K Wong and Graydon S Meneilly and Dariush H Elahi
DOI: 10.1038/oby.2007.39

Elevated free thyroxin levels following low molecular weight heparin treatment in a premature neonate
Acta Paediatrica
Alon Haim and Jean-Pierre Chanoine and Susan Albersheim and Thomas Mock
DOI: 10.1111/j.1651-2227.2008.01047.x

Healthy Buddies: a novel, peer-led health promotion program for the prevention of obesity and eating disorders in children in elementary school.
DOI: 10.1542/peds.2006-3003
PubMed: 17908726

Regulation of Appetite in Lean and Obese Adolescents after Exercise: Role of Acylated and Desacyl Ghrelin
The Journal of Clinical Endocrinology & Metabolism
Kerry J. Mackelvie and Graydon S. Meneilly and Dariush Elahi and Alfred C. K. Wong and Susan I. Barr and Jean-Pierre Chanoine
DOI: 10.1210/jc.2006-1028

Skewed X-chromosome inactivation is associated with primary but not secondary ovarian failure
American Journal of Medical Genetics Part A
Karla L. Bretherick and Daniel L. Metzger and Jean-Pierre Chanoine and Constadina Panagiotopoulos and Spencer K. Watson and Wan L. Lam and Margo R. Fluker and Carolyn J. Brown and Wendy P. Robinson
DOI: 10.1002/ajmg.a.31679

Attention to Sugar and Fat Metabolism
Myositis and you: A Guide to Juvenile Dermatomyositis for Patients, Families and Health Care Providers

Chapter 8: The clinical evaluation of the obese child or adolescent
Canadian Clinical Practice Guidelines on the Prevention and Management of Obesity

Individual Differences in the Hormonal Control of Appetite: A Step toward a (More) Successful Treatment of Childhood Overweight?
The Journal of Clinical Endocrinology & Metabolism
Jean-Pierre Chanoine
DOI: 10.1210/jc.2006-1218

Obestatin, Acylated and Total Ghrelin Concentrations in the Perinatal Rat Pancreas
Hormone Research in Paediatrics
Jean-Pierre Chanoine and Alfred C.K. Wong and Vicente Barrios
DOI: 10.1159/000093585

Genotypic heterogeneity and clinical phenotype in triple A syndrome: a review of the NIH experience 2000-2005.
Clinical genetics
DOI: 10.1111/j.1399-0004.2005.00482.x
PubMed: 16098009

Effect of Orlistat on Weight and Body Composition in Obese Adolescents
Jean-Pierre Chanoine and Sarah Hampl and Craig Jensen and Mark Boldrin and Jonathan Hauptman
DOI: 10.1001/jama.293.23.2873

Ghrelin, Peptide YY, Glucose-Dependent Insulinotropic Polypeptide, and Hunger Responses to a Mixed Meal in Anorexic, Obese, and Control Female Adolescents
The Journal of Clinical Endocrinology & Metabolism
Sue Stock and Pierre Leichner and Alfred C. K. Wong and Mohamed A. Ghatei and Timothy J. Kieffer and Stephen R. Bloom and Jean-Pierre Chanoine
DOI: 10.1210/jc.2004-1251

Iodine overload and severe hypothyroidism in a premature neonate
Journal of Pediatric Surgery
Minesh Khashu and Philippe Chessex and Jean-Pierre Chanoine
DOI: 10.1016/j.jpedsurg.2004.10.028

Ghrelin in growth and development.
Hormone research
DOI: 10.1159/000084688
PubMed: 15795510

Ghrelin is suppressed by glucagon and does not mediate glucagon-related growth hormone release.
Hormone research
DOI: 10.1159/000084569
PubMed: 15775713

Ghrelin Gene Expression Is Markedly Higher in Fetal Pancreas Compared with Fetal Stomach: Effect of Maternal Fasting
Jean-Pierre Chanoine and Alfred C. K. Wong
DOI: 10.1210/en.2004-0053

Selenium deficiency impairs corticosterone and leptin responses to adrenocorticotropin in the rat
Jean-Pierre Chanoine and Alfred C.K. Wong and Jean-Claude Lavoie
DOI: 10.1002/biof.5520200205

Elevated Umbilical Cord Ghrelin Concentrations in Small for Gestational Age Neonates
The Journal of Clinical Endocrinology & Metabolism
Juliet Farquhar and Mark Heiman and Alfred C. K. Wong and Richard Wach and Philippe Chessex and Jean-Pierre Chanoine
DOI: 10.1210/jc.2003-030265

Different Relationship Between Anthropometric Markers and Umbilical Cord Plasma Leptin in Asian and Caucasian Neonates
Pediatric Research
Louisa P K Yeung and Alfred C K Wong and Xiaohui Wang and Carl L Birmingham and Sabrina Lewicka and Jean-Pierre Chanoine
DOI: 10.1203/01.pdr.0000067140.75177.ed

Selenium and thyroid function in infants, children and adolescents
Jean-Pierre Chanoine
DOI: 10.1002/biof.5520190306

Umbilical Cord Ghrelin Concentrations in Asian and Caucasian Neonates
Hormone Research in Paediatrics
Jean-Pierre Chanoine and Louisa P.K. Yeung and Alfred C.K. Wong
DOI: 10.1159/000072522

Immunoreactive Ghrelin in Human Cord Blood: Relation to Anthropometry, Leptin, and Growth Hormone
Journal of Pediatric Gastroenterology and Nutrition
Jean-Pierre Chanoine and Louisa PK Yeung and Alfred CK Wong and Carl Laird Birmingham
DOI: 10.1097/00005176-200209000-00009

High prevalence of celiac disease in patients with type 1 diabetes detected by antibodies to endomysium and tissue transglutaminase.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie
DOI: 10.1155/2001/640796
PubMed: 11381296

Selenium Decreases Thyroglobulin Concentrations But Does Not Affect the Increased Thyroxine-to-Triiodothyronine Ratio in Children with Congenital Hypothyroidism1
The Journal of Clinical Endocrinology & Metabolism
Jean-Pierre Chanoine and Jean Nève and Sy Wu and Jean Vanderpas and Pierre Bourdoux
DOI: 10.1210/jcem.86.3.7312

Lipodystrophy in patients with juvenile dermatomyositis--evaluation of clinical and metabolic abnormalities.
The Journal of rheumatology
PubMed: 11296968

Should the Definition of Micropenis Vary According to Ethnicity?
Hormone Research in Paediatrics
Pik Shun Cheng and Jean-Pierre Chanoine
DOI: 10.1159/000050013

Modulation of steroidogenesis by selenium in a novel adrenal cell line developed using targeted tumorigenesis
Jean-Pierre Chanoine and Nathalie A. Compagnone and Alfred C. K. Wong and Synthia H. Mellon
DOI: 10.1002/biof.5520140129

Increased prevalence of celiac disease in girls with Turner syndrome detected using antibodies to endomysium and tissue transglutaminase.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie
DOI: 10.1155/2000/172914
PubMed: 11125180

Age-Related Perception of Stature, Acceptance of Therapy, and Psychosocial Functioning in Human Growth Hormone-Treated Girls with Turner’s Syndrome1
The Journal of Clinical Endocrinology & Metabolism
Katrien Lagrou and Danielle Xhrouet-Heinrichs and Claudine Heinrichs and Margarita Craen and Jean-Pierre Chanoine and Paul Malvaux and Jean-Pierre Bourguignon
DOI: 10.1210/jcem.83.5.4807

Iodine Intake Is a Main Determinant of Thyroid Hypersensitivity to Acute Iodine Overload
Clinical Pediatrics
Jean-Pierre Chanoine
DOI: 10.1177/000992289803700316

Decreased growth hormone response to glucagon in infants after an apnea of infancy
The Journal of Pediatrics
Jean-Pierre Chanoine and Elisabeth Rebuffat and André Kahn and Guy Van Vliet
DOI: 10.1016/s0022-3476(98)70019-8

Serum iodothyronine concentrations in intestinally decontaminated rats treated with a 5'-deiodinase type I inhibitor 6-anilino-2-thiouracil.
European journal of endocrinology
DOI: 10.1530/eje.0.1340519
PubMed: 8640307

Glucose, growth hormone, cortisol, and insulin responses to glucagon injection in normal infants, aged 0.5-12 months
Journal of Clinical Endocrinology & Metabolism
J. P. Chanoine
DOI: 10.1210/jc.80.10.3032

No apparent mineralocorticoid receptor defect in a series of sporadic cases of pseudohypoaldosteronism.
The Journal of clinical endocrinology and metabolism
DOI: 10.1210/jc.80.3.814
PubMed: 7883835

High-dose growth hormone therapy for short children born small for gestational age. Belgian Study Group for Paediatric Endocrinology.
Acta paediatrica (Oslo, Norway : 1992). Supplement
PubMed: 7949623

Primary ovarian failure after prepubertal marrow transplant in a girl.
Lancet (London, England)
DOI: 10.1016/s0140-6736(94)90860-5
PubMed: 7903766

Placental 5-Deiodinase Activity and Fetal Thyroid Hormone Economy Are Unaffected by Selenium Deficiency in the Rat
Pediatric Research
Jean-Pierre Chanoine and Sharon Alex and Scott Stone and Shih Lieh Fang and Irini Veronikis and Jack L Leonard and Lewis E Braverman
DOI: 10.1203/00006450-199309000-00009

Circulating calcitonin levels in healthy children and subjects with congenital hypothyroidism from birth to adolescence.
The Journal of clinical endocrinology and metabolism
DOI: 10.1210/jcem.77.2.8345063
PubMed: 8345063

The thyroid gland is a major source of circulating T3 in the rat.
The Journal of clinical investigation
DOI: 10.1172/jci116510
PubMed: 8514878

Selenium, Iodine, and the Thyroid
Iodine Deficiency in Europe
Jean-Pierre Chanoine and Jack L. Leonard and Lewis E. Braverman
DOI: 10.1007/978-1-4899-1245-9_8

The postnatal serum 3,5,3'-triiodothyronine (T3) surge in the rat is largely independent of extrathyroidal 5'-deiodination of thyroxine to T3
J. P. Chanoine
DOI: 10.1210/en.133.6.2604

Effects of selenium deficiency on thyroid hormone economy in rats
J. P. Chanoine
DOI: 10.1210/en.131.4.1787

Effect of in vivo administration of recombinant acidic fibroblast growth factor on thyroid function in the rat: induction of colloid goiter.
DOI: 10.1210/en.131.2.729
PubMed: 1379163

Selenium deficiency and type II 5'-deiodinase regulation in the euthyroid and hypothyroid rat: evidence of a direct effect of thyroxine
J. P. Chanoine
DOI: 10.1210/en.131.1.479

Role of transthyretin in the transport of thyroxine from the blood to the choroid plexus, the cerebrospinal fluid, and the brain.
DOI: 10.1210/en.130.2.933
PubMed: 1733735

Acidic fibroblast growth factor modulates gene expression in the rat thyroid in vivo
Journal of Cellular Biochemistry
Jean-Pierre Chanoine and Lewis E. Braverman and William J. DeVito and Gary S. Stein and Victoria Shalhoub and Jane B. Lian and Chris A. Huber
DOI: 10.1002/jcb.240500408

The role of transthyretin in the transport of thyroid hormone to cerebrospinal fluid and brain.
Acta medica Austriaca
PubMed: 1519447

Congenital hypothyroidism and cystic fibrosis.
Acta paediatrica Scandinavica
DOI: 10.1111/j.1651-2227.1991.tb11768.x
PubMed: 1755312

Radionuclide Imaging in Primary Permanent Congenital Hypothyroidism
Clinical Nuclear Medicine
DOI: 10.1097/00003072-199109000-00008

Determination of thyroid volume by ultrasound from the neonatal period to late adolescence.
European journal of pediatrics
DOI: 10.1007/bf02093716
PubMed: 2040346

Smoking during pregnancy: a significant cause of neonatal thyroid enlargement.
British journal of obstetrics and gynaecology
PubMed: 1998635

Growth Hormone (GH) Treatment in Short Normal Children: Absence of Influence of Time of Injection and Resistance to GH Autofeedback*
The Journal of Clinical Endocrinology & Metabolism
DOI: 10.1210/jcem-73-6-1269

Contribution of thyroid ultrasound and serum calcitonin to the diagnosis of congenital hypothyroidism.
Journal of endocrinological investigation
DOI: 10.1007/bf03349517
PubMed: 2184189

Neonatal Echographic Findings in Congenital Hypothyroidism
Research in Congenital Hypothyroidism
Marianne Spehl and Véronique Toppet and Jean-Pierre Chanoine and François Delange
DOI: 10.1007/978-1-4684-7580-7_17

Withdrawal of iodinated disinfectants at delivery decreases the recall rate at neonatal screening for congenital hypothyroidism.
Archives of disease in childhood
DOI: 10.1136/adc.63.10.1297-b
PubMed: 3196066

Increased recall rate at screening for congenital hypothyroidism in breast fed infants born to iodine overloaded mothers.
Archives of disease in childhood
DOI: 10.1136/adc.63.10.1207
PubMed: 3196047

Topical iodine, breastfeeding, and neonatal hypothyroidism.
Archives of disease in childhood
DOI: 10.1136/adc.63.1.106-a
PubMed: 3348642

Unusual ventilation-perfusion mismatch in partial anomalous venous return.
Pediatric radiology
DOI: 10.1007/bf00974090
PubMed: 3186326

Iodine overload and transient hypothyroidism in newborn infants
Revue medicale de Bruxelles
PubMed: 3363253

Unusual ventilation-perfusion patterns in primary lung tuberculosis.
Pediatric pulmonology
DOI: 10.1002/ppul.1950050110
PubMed: 3174274

[Iodine overload and transient hypothyroidism in newborn infants]
Revue medicale de Bruxelles
PubMed: 3363253

Iodine contamination of urine samples by test strips.
Clinical chemistry
PubMed: 3665054

Congenital anomalies associated with hypothyroidism.
Archives of disease in childhood
DOI: 10.1136/adc.61.11.1147-a
PubMed: 3789800

Neonatal cerebral ischaemia: early ultrasound/CT correlation.
Journal of neuroradiology. Journal de neuroradiologie
PubMed: 4009258


Current Projects
LiGHT project (Living Green, Healthy and Thrifty). This is a web-based program that emphasizes the beneficial effects of weight management on health, global environment and personal finances. It is performed in collaboration with the Childhood Obesity Foundation and Ayogo.

Current Project
Promoting education for families and health professionals in Pediatric Endocrinology and Diabetes

Current Projects
Promoting access to medicines in resource-constrained settings. This is a project that is partnership with regional societies for Pediatric Endocrinology and supported by Global Pediatric Endocrinology and Diabetes (GPED;www.globalpedendo.org)

Research Group Members

Jennifer Kwan, Research Coordinator