Long-term outcomes and disease course of children with juvenile idiopathic arthritis in the ReACCh-Out cohort: a two-centre experience.
Rheumatology (Oxford, England)
Chhabra A and Robinson C and Houghton K and Cabral DA and Morishita K and Tucker LB and Petty RE and Larché M and Batthish M and Guzman J
DOI: 10.1093/rheumatology/keaa118
PubMed: 32402087

Current Approach to the Evaluation and Management of Incomplete Kawasaki Disease in the Emergency Department.
Pediatric emergency care
Morishita KA and Goldman RD
DOI: 10.1097/pec.0000000000002259
PubMed: 33122594

Clinical and associated inflammatory biomarker features predictive of short-term outcomes in non-systemic juvenile idiopathic arthritis.
Rheumatology (Oxford, England)
Rezaei E and Hogan D and Trost B and Kusalik AJ and Boire G and Cabral DA and Campillo S and Chédeville G and Chetaille AL and Dancey P and Duffy C and Watanabe Duffy K and Gordon J and Rosenberg AM
DOI: 10.1093/rheumatology/kez615
PubMed: 31919503

Real-World Effectiveness of Common Treatment Strategies for Juvenile Idiopathic Arthritis: Results From a Canadian Cohort.
Arthritis care & research
Chhabra A and Oen K and Huber AM and Shiff NJ and Boire G and Benseler SM and Berard RA and Scuccimarri R and Feldman BM and Lim LSH and Barsalou J and Bruns A and Cabral DA and ReACCh-Out Investigators
DOI: 10.1002/acr.23922
PubMed: 31074591

Associations of clinical and inflammatory biomarker clusters with juvenile idiopathic arthritis categories.
Rheumatology (Oxford, England)
Rezaei E and Hogan D and Trost B and Kusalik AJ and Boire G and Cabral DA and Campillo S and Chédeville G and Chetaille AL and Dancey P and Duffy C and Duffy KW and Eng SWM and Gordon J and BBOP Study Group
DOI: 10.1093/rheumatology/kez382
PubMed: 32321162

Worse Quality of Life, Function, and Pain in Children With Enthesitis, Irrespective of Their Juvenile Arthritis Category.
Arthritis care & research
Rumsey DG and Guzman J and Rosenberg AM and Huber AM and Scuccimarri R and Shiff NJ and Bruns A and Feldman BM and Eurich DT and Research in Arthritis in Canadian Children Emphasizing Outcomes Investigators
DOI: 10.1002/acr.23844
PubMed: 30740939

Kawasaki disease recognition and treatment
Canadian family physician Medecin de famille canadien
Morishita, K.A. and Goldman, R.D.

Complexity in unclassified auto-inflammatory disease: a case report illustrating the potential for disease arising from the allelic burden of multiple variants.
Pediatric rheumatology online journal
Tucker LB and Lamot L and Niemietz I and Chung BK and Cabral DA and Houghton K and Petty RE and Morishita KA and Rice GI and Turvey SE and Gibson WT and Brown KL
DOI: 10.1186/s12969-019-0374-x
PubMed: 31660995

Identification of novel Adenosine Deaminase 2 gene variants and varied clinical phenotype in pediatric vasculitis.
Arthritis & rheumatology (Hoboken, N.J.)
Gibson KM and Morishita KA and Dancey P and Moorehead P and Drögemöller B and Han X and Graham J and Hancock RE and Foell D and Benseler S and Luqmani R and Yeung RSM and Shenoi S and PedVas investigators network
DOI: 10.1002/art.40913
PubMed: 31008556

Innate Control of Tissue-Reparative Human Regulatory T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Lam AJ and MacDonald KN and Pesenacker AM and Juvet SC and Morishita KA and Bressler B and iGenoMed Consortium and Pan JG and Sidhu SS and Rioux JD and Levings MK
DOI: 10.4049/jimmunol.1801330
PubMed: 30850479

Predicting Which Children with Juvenile Idiopathic Arthritis Will Not Attain Early Remission with Conventional Treatment: Results from the ReACCh-Out Cohort.
The Journal of rheumatology
Guzman J and Henrey A and Loughin T and Berard RA and Shiff NJ and Jurencak R and Huber AM and Oen K and Gerhold K and Feldman BM and Scuccimarri R and Houghton K and Chédeville G and ReACCh-Out Investigators
DOI: 10.3899/jrheum.180456
PubMed: 30647178

Prospective Determination of the Incidence and Risk Factors of New-Onset Uveitis in Juvenile Idiopathic Arthritis: The Research in Arthritis in Canadian Children Emphasizing Outcomes Cohort
Arthritis Care and Research
Lee, J.J.Y. and Duffy, C.M. and Guzman, J. and Oen, K. and Barrowman, N. and Rosenberg, A.M. and Shiff, N.J. and Boire, G. and Stringer, E. and Spiegel, L. and Morishita, K.A. and Lang, B. and Reddy, D. and Huber, A.M. and Cabral, D.A. and Feldman, B.M. and Yeung, R.S.M. and Tucker, L.B. and Watanabe Duffy, K.
DOI: 10.1002/acr.23783

Feasibility and safety of a 6-month exercise program to increase bone and muscle strength in children with juvenile idiopathic arthritis
Pediatric Rheumatology
DOI: 10.1186/s12969-018-0283-4

Natural history and extracutaneous involvement of congenital morphea: Multicenter retrospective cohort study and literature review
Pediatric Dermatology
Mark Mansour and Carmen Liy Wong and Francesco Zulian and Suzanne Li and Kimberly Morishita and Eluen Ann Yeh and Katie Stewart and Ronald M. Laxer and Elena Pope
DOI: 10.1111/pde.13605

Health-Related Quality of Life in an Inception Cohort of Children With Juvenile Idiopathic Arthritis: A Longitudinal Analysis
Arthritis Care & Research
DOI: 10.1002/acr.23236

Trajectories of pain severity in juvenile idiopathic arthritis
DOI: 10.1097/j.pain.0000000000001064

Therapeutic Management of Pediatric Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis
Current Treatment Options in Rheumatology
Kimberly A. Morishita and Georgina Tiller and David A. Cabral
DOI: 10.1007/s40674-017-0077-8

Clinical practice variation and need for pediatric-specific treatment guidelines among rheumatologists caring for children with ANCA-associated vasculitis: an international clinician survey.
Pediatric rheumatology online journal
Westwell-Roper C and Lubieniecka JM and Brown KL and Morishita KA and Mammen C and Wagner-Weiner L and Yen E and Li SC and O'Neil KM and Lapidus SK and Brogan P and Cimaz R and for ARChiVe Investigators Network within the PedVas initiative
DOI: 10.1186/s12969-017-0191-z
PubMed: 28784150

Growth and weight gain in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort.
Pediatric rheumatology online journal
DOI: 10.1186/s12969-017-0196-7
PubMed: 28830457

Early Outcomes in Children With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.
Arthritis & rheumatology (Hoboken, N.J.)
Morishita KA and Moorthy LN and Lubieniecka JM and Twilt M and Yeung RSM and Toth MB and Shenoi S and Ristic G and Nielsen SM and Luqmani RA and Li SC and Lee T and Lawson EF and ARChiVe Investigators Network within the PedVas Initiative
DOI: 10.1002/art.40112
PubMed: 28371513

The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus
Clinical Immunology
Robert J. Ragotte and Anita Dhanrajani and Julian Pleydell-Pearce and Kate L. Del Bel and Maja Tarailo-Graovac and Clara van Karnebeek and Jefferson Terry and Christof Senger and Margaret L. McKinnon and Michael Seear and Julie S. Prendiville and Lori B. Tucker and Kristin Houghton and David A. Cabral and Jaime Guzman and Ross E. Petty and Kelly L. Brown and Jenny Tekano and John Wu and Kimberly A. Morishita and Stuart E. Turvey
DOI: 10.1016/j.clim.2016.12.006

Granulomatosis with Polyangiitis in Children
Pediatric Rheumatology
David A. Cabral and Kimberly Morishita
DOI: 10.1007/978-981-10-1750-6_36

Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study
Arthritis & Rheumatology
David A. Cabral and Debra L. Canter and Eyal Muscal and Kabita Nanda and Dawn M. Wahezi and Steven J. Spalding and Marinka Twilt and Susanne M. Benseler and Sarah Campillo and Sirirat Charuvanij and Paul Dancey and Barbara A. Eberhard and Melissa E. Elder and Aimee Hersh and Gloria C. Higgins and Adam M. Huber and Raju Khubchandani and Susan Kim and Marisa Klein-Gitelman and Mikhail M. Kostik and Erica F. Lawson and Tzielan Lee and Joanna M. Lubieniecka and Deborah McCurdy and Lakshmi N. Moorthy and Kimberly A. Morishita and Susan M. Nielsen and Kathleen M. O'Neil and Andreas Reiff and Goran Ristic and Angela B. Robinson and Angelyne Sarmiento and Susan Shenoi and Mary B. Toth and Heather A. Van Mater and Linda Wagner-Weiner and Jennifer E. Weiss and Andrew J. White and Rae S. M. Yeung and the ARChiVe Investigators Network within the PedVas Initiative
DOI: 10.1002/art.39729

T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression
Journal of Clinical Investigation
Scott J. Patterson and Anne M. Pesenacker and Adele Y. Wang and Jana Gillies and Majid Mojibian and Kim Morishita and Rusung Tan and Timothy J. Kieffer and C. Bruce Verchere and Constadina Panagiotopoulos and Megan K. Levings
DOI: 10.1172/jci83987

Development of System-level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada.
The Journal of rheumatology
DOI: 10.3899/jrheum.150839
PubMed: 26773106

Antineutrophil Cytoplasmic Antibody Associated Vasculitis
Textbook of Pediatric Rheumatology
David A. Cabral and Kimberly Morishita
DOI: 10.1016/b978-0-323-24145-8.00036-3

The risk and nature of flares in juvenile idiopathic arthritis: Results from the ReACCh-Out cohort
Annals of the Rheumatic Diseases
Guzman, J. and Oen, K. and Huber, A.M. and Duffy, K.W. and Boire, G. and Shiff, N. and Berard, R.A. and Levy, D.M. and Stringer, E. and Scuccimarri, R. and Morishita, K. and Johnson, N. and Cabral, D.A. and Rosenberg, A.M. and Larché, M. and Dancey, P. and Petty, R.E. and Laxer, R.M. and Silverman, E. and Miettunen, P. and Chetaille, A.-L. and Haddad, E. and Houghton, K. and Spiegel, L. and Turvey, S.E. and Schmeling, H. and Lang, B. and Ellsworth, J. and Ramsey, S.E. and Bruns, A. and Roth, J. and Campillo, S. and Benseler, S. and Chédeville, G. and Schneider, R. and Tse, S.M.L. and Bolaria, R. and Gross, K. and Feldman, B. and Feldman, D. and Cameron, B. and Jurencak, R. and Dorval, J. and LeBlanc, C. and St. Cyr, C. and Gibbon, M. and Yeung, R.S.M. and Duffy, C.M. and Tucker, L.B.
DOI: 10.1136/annrheumdis-2014-207164

T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression
Journal of Clinical Investigation
Patterson, S.J. and Pesenacker, A.M. and Wang, A.Y. and Gillies, J. and Mojibian, M. and Morishita, K. and Tan, R. and Kieffer, T.J. and Verchere, C.B. and Panagiotopoulos, C. and Levings, M.K.
DOI: 10.1172/JCI83987

The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort.
Annals of the rheumatic diseases
Guzman J and Oen K and Tucker LB and Huber AM and Shiff N and Boire G and Scuccimarri R and Berard R and Tse SM and Morishita K and Stringer E and Johnson N and Levy DM and Duffy KW and ReACCh-Out investigators
DOI: 10.1136/annrheumdis-2014-205372
PubMed: 24842571

Pediatric vasculitis
Current Opinion in Rheumatology
Kimberly Morishita and Kelly Brown and David Cabral
DOI: 10.1097/bor.0000000000000203

The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort.
Annals of the rheumatic diseases
DOI: 10.1186/1546-0096-12-s1-o9
PubMed: 25985972

Pediatric vasculitis: Advances in treatment
Current Opinion in Rheumatology
Morishita, K. and Brown, K. and Cabral, D.
DOI: 10.1097/BOR.0000000000000203

Early Atlantoaxial Subluxation in Enthesitis-related Arthritis
The Journal of Rheumatology
DOI: 10.3899/jrheum.131206

Chylous Pericardial Effusion in Granulomatosis with Polyangiitis
Nicholas Larkins and Kevin C Harris and Kimberly Morishita and Douglas G Matsell
DOI: 10.1111/nep.12262

A13: The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh Out) Cohort: Prospective Determination of the Incidence of New Onset Uveitis in Juvenile Idiopathic Arthritis
Arthritis & Rheumatology
Karen N Watanabe Duffy and Jennifer Lee and Jaime Guzman and Nick Barrowman and Kimberly Morishita and Lynn R. Spiegel and Elizabeth Stringer and Michele Gibbon and Rae SM Yeung and Lori B. Tucker and Kiem Oen and Ciarán M. Duffy and ReACChOut Investigators
DOI: 10.1002/art.38424

Association of health-related quality of life in childhood-onset systemic lupus erythematosus with ethnicity: Results from a multiethnic multicenter canadian cohort
Arthritis Care and Research
Levy, D.M. and Peschken, C.A. and Tucker, L.B. and Chédeville, G. and Huber, A.M. and Pope, J.E. and Silverman, E.D. and Petty, R. and Cabral, D. and Houghton, K. and Morishita, K. and Campillo, S. and Duffy, K. and Scuccimarri, R. and Lang, B. and Ramsey, S. and Warner, A. and Ng, L. and Fortin, P. and Urowitz, M. and Gladman, D. and Albert, L. and Carette, S. and Inman, R. and McKenzie, T. and Clarke, A. and Pineau, C. and Bernatsky, S. and Tobaly, M. and Santopietro, T. and Smith, C.D. and Simpson, S. and Smith, K. and Zummer, M. and Ferland, D. and Arbillaga, H. and Wehlage, A. and Hudson, M. and Baron, M. and Berkson, L. and Bernstein, J. and Hanly, J. and Hewitt, S. and Ouimet, J. and Hitchon, C. and Craig, A. and Moyen, M.
DOI: 10.1002/acr.22363

Severe Vocal Cord Dysfunction: An Unusual Complication of Juvenile Dermatomyositis
The Journal of Rheumatology
DOI: 10.3899/jrheum.121338

Do adult disease severity subclassifications predict use of cyclophosphamide in children with ANCA-associated vasculitis? An analysis of ARChiVe study treatment decisions.
The Journal of rheumatology
Morishita K and Guzman J and Chira P and Muscal E and Zeft A and Klein-Gitelman M and Uribe AG and Abramson L and Benseler SM and Eberhard A and Ede K and Hashkes PJ and Hersh AO and ARChiVe Investigators Network
DOI: 10.3899/jrheum.120299
PubMed: 22859342

Assessing the performance of the Birmingham Vasculitis Activity Score at diagnosis for children with antineutrophil cytoplasmic antibody-associated vasculitis in A Registry for Childhood Vasculitis (ARChiVe).
The Journal of rheumatology
Morishita K and Li SC and Muscal E and Spalding S and Guzman J and Uribe A and Abramson L and Baszis K and Benseler S and Bowyer S and Campillo S and Chira P and Hersh AO and Higgins G and ARChiVe Investigators Network
DOI: 10.3899/jrheum.111030
PubMed: 22337238

Familial Takayasu arteritis - a pediatric case and a review of the literature
Pediatric Rheumatology
Kimberly A Morishita and Karen Rosendahl and Paul A Brogan
DOI: 10.1186/1546-0096-9-6

Mortality in wegener's granulomatosis: A bimodal pattern
Luqmani, R. and Suppiah, R. and Edwards, C.J. and Phillip, R. and Maskell, J. and Culliford, D. and Jayne, D. and Morishita, K. and Arden, N.
DOI: 10.1093/rheumatology/keq351

Musculoskeletal manifestations of mucopolysaccharidoses
Morishita, K. and Petty, R.E.
DOI: 10.1093/rheumatology/ker397

Serious musculoskeletal infections in children receiving anti-tumor necrosis factor-a therapy: a case series
Clinical Rheumatology
Kimberly Morishita and Ross Petty and Robyn Cairns and Roxana Bolaria and David Cabral and Stuart Turvey
DOI: 10.1007/s10067-010-1410-x

Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis.
The Journal of rheumatology
Ortiz-Alvarez O and Morishita K and Avery G and Green J and Petty RE and Tucker LB and Malleson PN and Cabral DA
PubMed: 15570658

Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis
Journal of Rheumatology
Ortiz-Alvarez, O. and Morishita, K. and Avery, G. and Green, J. and Petty, R.E. and Tucker, L.B. and Malleson, P.N. and Cabral, D.A.


The role of T regulatory (Treg) cells in control and remission of JIA.
This study is looking at Treg function in the blood and synovial fluid of children with JIA at different disease states (active, inactive on medications, inactive off medications). The study will evaluate whether there is dysregulation in Treg function that may predict who is in true remission and who may be at increased risk of disease flare.

Predictors of outcomes in pediatric ANCA associated vasculitis.
This study will build on the previous study listed above. Clinical characteristics at baseline will be evaluated as potential predictors of outcome and models will be built so see if a combination of features may better predict certain outcomes compared to individual baseline characteristics.

Early outcomes in pediatric antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV): A Pediatric Vasculitis Initiative (PedVas) Study.
This study reported on 6- and 12-month outcomes in 79 children with AAV. Outcomes included remission rates, relapse rates, medication usage, damage, and rates of dialysis dependence. This was the largest study to date reporting early outcomes in this group of patients.


Training Grants

Canada Graduate Scholarship Master's Award, CIHR, 2010-2011. $17,500. UBC Clinical Investigator Program, 2010-2011. $70,000.

Research Grants

Clinical Translational Research Seed Grant, CFRI, 2014-2015. $5000.

Honours & Awards

Future Leaders in Rheumatology Training (FLIRT) Program. Nominated by peers to participate in this 2-year program. Canadian Rheumatology Association. 2012-2014.

Graduate Entrance Scholarship, University of British Columbia, 2011.

Research Group Members

Angelyne Rivera, Research Manager