- Overview
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My research aim is to understand the long-term outcomes of children who need neonatal intensive care, the predictors and exposures that influence these outcomes, and ultimately the modifiable factors that can improve health and developmental outcomes. By identifying strategies to better protect the vulnerable developing brain of these infants, my goal is to improve their care and help each of them live to their fullest potential.
- Publications
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Neuroprotection for neonatal hypoxic–ischemic encephalopathy: A review of novel therapies evaluated in clinical studies
Developmental Medicine and Child Neurology
Chan, N.H. and Hawkins, C.C. and Rodrigues, B.V. and Cornet, M.-C. and Gonzalez, F.F. and Wu, Y.W.
DOI: 10.1111/dmcn.16184
2025Long-term health outcomes of preterm birth: a narrative review
Frontiers in Pediatrics
Gette, F. and Aziz Ali, S. and Ho, M.S.P. and Richter, L.L. and Chan, E.S. and Yang, C.L. and Kieran, E. and Mammen, C. and Roberts, A. and Kang, K.T. and Wong, J. and Rassekh, S.R. and Castaldo, M. and Harris, K.C. and Lee, J. and Lam, C.K.L. and Chan, N.H. and Lisonkova, S. and Ting, J.Y.
DOI: 10.3389/fped.2025.1565897
2025Sociodemographic Characteristics and Behavioral Outcomes in Infants With Hypoxic-Ischemic Encephalopathy Treated With Therapeutic Hypothermia
Pediatric Neurology
Taketa, E.S. and Chan, N. and Rogers, E.E. and Glass, H.C. and Heagerty, P.J. and Juul, S.E. and Wu, Y.W. and Cornet, M.-C.
DOI: 10.1016/j.pediatrneurol.2025.04.006
2025Assessing Early Severity of Hypoxic-Ischemic Encephalopathy: The Role of Electroencephalogram Background in Addition to Sarnat Exam
Journal of Pediatrics
Cornet, M.-C. and Numis, A.L. and Monsell, S.E. and Chan, N.H. and Gonzalez, F.F. and Comstock, B.A. and Juul, S.E. and Wusthoff, C.J. and Wu, Y.W. and Glass, H.C.
DOI: 10.1016/j.jpeds.2024.114411
2025Cumulative caffeine exposure predicts neurodevelopmental outcomes in premature infants
Pediatric Research
Ostrem, B.E.L. and Odell, E. and Grelli, K.N. and Kramer, K. and Chan, N. and Jiang, F. and Xu, D. and Barkovich, A.J. and Barkovich, M.J. and Ferriero, D.M. and Gano, D.
DOI: 10.1038/s41390-025-04387-1
2025Assessing Semiregional Cerebral Oxygen Consumption (CMRO2) in Preterm Neonates: A Quantitative MRI Cohort Study With Exploratory Analysis of Respiratory Support
NMR in Biomedicine
Zhu, C. and Chan, N. and Chacko, A. and Holsti, L. and Grunau, R. and Weber, A.
DOI: 10.1002/nbm.70065
2025The impact of a care bundle with an emphasis on hemodynamic assessment on the short-term outcomes in neonates with congenital diaphragmatic hernia
Journal of Perinatology
Kuan, M.T.Y. and Yadav, K. and Castaldo, M. and Tan, J. and Chan, N.H. and Traynor, M. and Hosking, M. and Skarsgard, E. and Ting, J.Y.
DOI: 10.1038/s41372-023-01807-0
2024Utilization of a novel mobile application, “HBB Prompt”, to reduce Helping Babies Breathe skills decay
Plos Global Public Health
Chan, N.H.-M. and Merali, H.S. and Mistry, N. and Kealey, R. and Campbell, D.M. and Morris, S.K. and Data, S.
DOI: 10.1371/journal.pgph.0000705
2023Impact of Differing Language Background Exposures on Bayley-III Language Assessment in a National Cohort of Children Born Less than 29 Weeks’ Gestation
Children
Chan, N.H.-M. and Synnes, A. and Grunau, R.E. and Colby, L. and Petrie, J. and Elfring, T. and Richter, L. and Hendson, L. and Banihani, R. and Luu, T.M.
DOI: 10.3390/children9071048
2022Development of a novel mobile application, HBB Prompt, with human factors and user-centred design for Helping Babies Breathe skills retention in Uganda
BMC Medical Informatics and Decision Making
Chan, N.H.-M. and Merali, H.S. and Mistry, N. and Kealey, R. and Campbell, D.M. and Morris, S.K. and Data, S.
DOI: 10.1186/s12911-021-01406-z
2021Call to Action: Children with Intestinal Failure Deserve Routine Screening for Neurodevelopmental Disabilities
Journal of Pediatric Gastroenterology and Nutrition
Chan, N. and Rogers, E.E. and Glass, H.C.
DOI: 10.1097/MPG.0000000000002570
2020A Simulation-Based Pilot Study of a Mobile Application (NRP Prompt) as a Cognitive Aid for Neonatal Resuscitation Training
Simulation in Healthcare
Chan, N.H. and Mistry, N. and Campbell, D.M.
DOI: 10.1097/SIH.0000000000000353
2019Designing and evaluating a novel mobile application for Helping Babies Breathe skills retention in Uganda: Comparative study protocol
BMJ Paediatrics Open
Merali, H.S. and Chan, N.H.-M. and Mistry, N. and Kealey, R. and Campbell, D. and Morris, S.K. and Data, S.
DOI: 10.1136/bmjpo-2019-000561
2019 - Research
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Feasibility and reliability of applying Prechtl’s Assessment of General Movements for preterm infants through telemedicine
Early identification of neurodevelopmental impairment allows for targeted early interventions that may ultimately improve developmental trajectories. I co-lead an ongoing clinical research study at University of California, Davis comparing standard video review versus real-time telemedicine assessment of Prechtl’s general movements, a validated tool to identify infants at high risk of cerebral palsy in the first months of life. Our work is funded by a grant from the Children’s Miracle Network. By testing the ability to capture recordings through telemedicine, we hope to expand the reach of Prechtl’s assessment to patients who live in remote communities and improve access to early identification of cerebral palsy, thereby improving functional outcomes.GrantsChildren’s Miracle Network Grant
Grand Challenges Canada Stars in Global Health
Honours & AwardsSommer Scholar, Johns Hopkins Bloomberg School of Public Health, Class of 2015
Neonatal Resuscitation Program Young Investigator Award, 2013
Research holds out hope for improved Rett syndrome treatment
To mark Rett Syndrome Awareness Month, BCCHR contributes to foster understanding about this complex neurological disorder that affects multiple organ systems and can lead to severe impairments that disrupt key aspects of an individual’s life — most of them female patients.
