- Overview
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My research aim is to understand the long-term outcomes of children who need neonatal intensive care, the predictors and exposures that influence these outcomes, and ultimately the modifiable factors that can improve health and developmental outcomes. By identifying strategies to better protect the vulnerable developing brain of these infants, my goal is to improve their care and help each of them live to their fullest potential.
- Publications
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Sociodemographic Characteristics and Behavioral Outcomes in Infants With Hypoxic-Ischemic Encephalopathy Treated With Therapeutic Hypothermia
Pediatric Neurology
Emily S. Taketa and Natalie Chan and Elizabeth E. Rogers and Hannah C. Glass and Patrick J. Heagerty and Sandra E. Juul and Yvonne W. Wu and Marie-Coralie Cornet
DOI: 10.1016/j.pediatrneurol.2025.04.006
07/2025Neuroprotection for neonatal hypoxic–ischemic encephalopathy: A review of novel therapies evaluated in clinical studies
Developmental Medicine & Child Neurology
Natalie H. Chan and Cheryl C. Hawkins and Benjamin V. Rodrigues and Marie-Coralie Cornet and Fernando F. Gonzalez and Yvonne W. Wu
DOI: 10.1111/dmcn.16184
05/2025The impact of a care bundle with an emphasis on hemodynamic assessment on the short-term outcomes in neonates with congenital diaphragmatic hernia
Journal of Perinatology
Mimi T. Y. Kuan and Krishan Yadav and Michael Castaldo and Jason Tan and Natalie H. Chan and Michael Traynor and Martin Hosking and Erik Skarsgard and Joseph Y. Ting
DOI: 10.1038/s41372-023-01807-0
03/2024Utilization of a novel mobile application, “HBB Prompt”, to reduce Helping Babies Breathe skills decay
PLOS Global Public Health
Natalie Hoi-Man Chan and Hasan S. Merali and Niraj Mistry and Ryan Kealey and Douglas M. Campbell and Shaun K. Morris and Santorino Data
DOI: 10.1371/journal.pgph.0000705
05/2023Impact of Differing Language Background Exposures on Bayley-III Language Assessment in a National Cohort of Children Born Less than 29 Weeks’ Gestation
Children
Chan, N.H.-M. and Synnes, A. and Grunau, R.E. and Colby, L. and Petrie, J. and Elfring, T. and Richter, L. and Hendson, L. and Banihani, R. and Luu, T.M.
DOI: 10.3390/children9071048
2022Development of a novel mobile application, HBB Prompt, with human factors and user-centred design for Helping Babies Breathe skills retention in Uganda
BMC Medical Informatics and Decision Making
Chan, N.H.-M. and Merali, H.S. and Mistry, N. and Kealey, R. and Campbell, D.M. and Morris, S.K. and Data, S.
DOI: 10.1186/s12911-021-01406-z
2021Call to Action: Children with Intestinal Failure Deserve Routine Screening for Neurodevelopmental Disabilities
Journal of Pediatric Gastroenterology and Nutrition
Chan, N. and Rogers, E.E. and Glass, H.C.
DOI: 10.1097/MPG.0000000000002570
2020A Simulation-Based Pilot Study of a Mobile Application (NRP Prompt) as a Cognitive Aid for Neonatal Resuscitation Training
Simulation in Healthcare
Chan, N.H. and Mistry, N. and Campbell, D.M.
DOI: 10.1097/SIH.0000000000000353
2019Designing and evaluating a novel mobile application for Helping Babies Breathe skills retention in Uganda: Comparative study protocol
BMJ Paediatrics Open
Merali, H.S. and Chan, N.H.-M. and Mistry, N. and Kealey, R. and Campbell, D. and Morris, S.K. and Data, S.
DOI: 10.1136/bmjpo-2019-000561
2019 - Research
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Feasibility and reliability of applying Prechtl’s Assessment of General Movements for preterm infants through telemedicine
Early identification of neurodevelopmental impairment allows for targeted early interventions that may ultimately improve developmental trajectories. I co-lead an ongoing clinical research study at University of California, Davis comparing standard video review versus real-time telemedicine assessment of Prechtl’s general movements, a validated tool to identify infants at high risk of cerebral palsy in the first months of life. Our work is funded by a grant from the Children’s Miracle Network. By testing the ability to capture recordings through telemedicine, we hope to expand the reach of Prechtl’s assessment to patients who live in remote communities and improve access to early identification of cerebral palsy, thereby improving functional outcomes.GrantsChildren’s Miracle Network Grant
Grand Challenges Canada Stars in Global Health
Honours & AwardsSommer Scholar, Johns Hopkins Bloomberg School of Public Health, Class of 2015
Neonatal Resuscitation Program Young Investigator Award, 2013
Study reveals that sucrose may not reduce the impact of neonatal pain exposure on long-term outcomes
Infants born two to four months early are exposed to mildly painful procedures in the NICU that are essential to monitor their health. As research shows that exposure to daily pain is associated with poorer behavioural and cognitive outcomes later in life, a common pain management strategy is to give those babies sucrose, but a BCCHR study shows evidence that a sugar solution doesn’t reduce these negative effects of pain exposure in the long term.
