Maternal and Environmental Influences on the Fetal Epigenome
Hear about the Harvard Epigenetic Birth Cohort and the epigenetic effects of maternal smoking, BPA exposure, depression, and diet on fetal development and health outcomes. Presented by Dr. Karin B. Michels, Professor & Chair, Department of Epidemiology, Fielding School of Public Health, University of California. [Note: the sound quality improves around 4:00 minutes.] (2016)
We asked Dr. Genelle Healey about emerging research that shows associations between consuming food additives and development or worsening of inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
A healthy diet complete with plenty of fruits and vegetables is an important contributor to reaching and maintaining a healthy body weight. It is also protective against many chronic diseases such as cardiovascular disease, type 2 diabetes, and cancer.
A team of researchers at BC Children's is doing a deep dive into why the immune system attacks islet cells — the cells in the pancreas that produce insulin — and how metabolic pathways are involved. This could lead to new treatments for type 1 diabetes.
Very preterm babies have an increased risk of ongoing medical complications and neurodevelopmental issues throughout their lifespan. New research suggests that a specially designed epigenetic “clock” can indicate abnormally accelerated molecular aging, which may be associated with these long-term impacts and warrants further study.
Lindsay Pallo and Raelyn Gallant were both diagnosed with type 1 diabetes as children. Now they’re conducting diabetes research in Dr. Bruce Verchere’s lab. Read about their lived experience and how that enriches their work.
We believe there’s nothing we can’t do with your support. It can take years to turn scientific breakthrough into new interventions and treatments. Funding helps speed the pace of change. When given the resources, we can bring transformative therapies – and hope – out of the laboratory and into the clinic to save and improve children’s lives.