Overview

As part of an inter-disciplinary team of engineers, computer scientists, and health care providers, I am involved in a wide range of projects focusing on the development and application of new technology, primarily in the pediatric anesthesia and intensive care setting. My main goal is to extract clinically-useful information from vital signs and other clinical data, and to transform these data into information for better, more timely, and more efficient decision-making by clinicians.

Publications

Clinician-driven design of VitalPAD – an intelligent monitoring and communication device to improve patient safety in the Intensive Care Unit
IEEE Journal of Translational Engineering in Health and Medicine
Luisa Flohr, Shaylene Beaudry, K Taneille Johnson, Nicholas West, Catherine M Burns, J Mark Ansermino, Guy A Dumont, David Wensley, Peter Skippen, Matthias Gorges
DOI: 10.1109/jtehm.2018.2812162
2018

Feasibility of continuous sedation monitoring in critically ill intensive care unit patients using the NeuroSENSE WAVCNS index
Journal of Clinical Monitoring and Computing
Nicholas West, Paul B. McBeth, Sonia M. Brodie, Klaske van Heusden, Sarah Sunderland, Guy A. Dumont, Donald E. G. Griesdale, J. Mark Ansermino, Matthias Görges
DOI: 10.1007/s10877-018-0115-6
02/2018

Data Access and Usage Practices Across a Cohort of Researchers at a Large Tertiary Pediatric Hospital: Qualitative Survey Study
JMIR Medical Informatics
Hoi Ki Kiki Ho, Matthias Görges, Elodie Portales-Casamar
DOI: 10.2196/medinform.8724
05/2018

Mortality Risk Using a Pediatric Quick Sequential (Sepsis-Related) Organ Failure Assessment Varies With Vital Sign Thresholds
Pediatric Critical Care Medicine
Cheryl Peters, Srinivas Murthy, Rollin Brant, Niranjan Kissoon, Matthias Görges
DOI: 10.1097/pcc.0000000000001598
06/2018

Effect of preoperative warming on intraoperative hypothermia: a randomized-controlled trial
Canadian Journal of Anesthesia/Journal canadien d'anesthésie
Aaron Lau and Nasim Lowlaavar and Erin M. Cooke and Nicholas West and Alexandra German and Dan J. Morse and Matthias Görges and Richard N. Merchant
DOI: 10.1007/s12630-018-1161-8
09/2018

An Ethnographic Observational Study to Evaluate and Optimize the Use of Respiratory Acoustic Monitoring in Children Receiving Postoperative Opioid Infusions
Anesthesia & Analgesia
Matthias Görges, Nicholas C. West, Nancy A. Christopher, Jennifer L. Koch, Sonia M. Brodie, Nasim Lowlaavar, Gillian R. Lauder, J. Mark Ansermino
DOI: 10.1213/ane.0000000000001127
04/2016

Using machine-to-machine / “Internet of Things” communication to simplify medical device information exchange
2014 International Conference on the Internet of Things (IOT)
Matthias Gorges and Guy A Dumont and Christian L Petersen and J Mark Ansermino
DOI: 10.1109/iot.2014.7030114
10/2014

Sequential allocation trial design in anesthesia: an introduction to methods, modeling, and clinical applications
Pediatric Anesthesia
Matthias Görges, Guohai Zhou, Rollin Brant, J. Mark Ansermino
DOI: 10.1111/pan.13088
03/2017

ICU nurses' evaluations of integrated information displays on user satisfaction and perceived mental workload.
Sven H Koch, Dwayne Westenskow, Charlene Weir, Jim Agutter, Maral Haar, Matthias Görges, David Liu, Nancy Staggers
DOI: 10.3233/978-1-61499-101-4-383
PubMed: 22874217
01/2012

Improving alarm performance in the medical intensive care unit using delays and clinical context.
Matthias Görges, Boaz A Markewitz, Dwayne R Westenskow
DOI: 10.1213/ane.0b013e31819bdfbb
PubMed: 19372334
05/2009

Clinician-Driven Design of –An Intelligent Monitoring and Communication Device to Improve Patient Safety in the Intensive Care Unit
IEEE Journal of Translational Engineering in Health and Medicine
Luisa Flohr, Shaylene Beaudry, K Taneille Johnson, Nicholas West, Catherine M Burns, J Mark Ansermino, Guy A Dumont, David Wensley, Peter Skippen, Matthias Gorges
DOI: 10.1109/JTEHM.2018.2812162
2018

Design and Evaluation of a Closed-Loop Anesthesia System With Robust Control and Safety System
Anesthesia & Analgesia
Nicholas West, Klaske van Heusden, Matthias Görges, Sonia Brodie, Aryannah Rollinson, Christian L. Petersen, Guy A. Dumont, J. Mark Ansermino, Richard N. Merchant
DOI: 10.1213/ane.0000000000002663
11/2017

Closed-Loop Control of Total Intravenous Anesthesia During Significant Intraoperative Blood Loss A Case Report
A & A Case Reports
Sonia M. Brodie, Matthias Görges, J. Mark Ansermino, Guy A. Dumont, Richard N. Merchant
DOI: 10.1213/xaa.0000000000000576
07/2017

In Response
Anesthesia & Analgesia
Christian Leth Petersen, Matthias Görges, Roslyn Massey, Guy Albert Dumont, J. Mark Ansermino
DOI: 10.1213/ane.0000000000001957
05/2017

Using physiological monitoring data for performance feedback: an initiative using thermoregulation metrics
Canadian Journal of Anesthesia/Journal canadien d'anesthésie
Matthias Görges, Nicholas C. West, Simon D. Whyte
DOI: 10.1007/s12630-016-0762-3
03/2017

Developing an objective method for analyzing vital signs changes in neonates during general anesthesia
Pediatric Anesthesia
Matthias Görges, Nicholas C. West, Edda Karlsdóttir, J. Mark Ansermino, Myles Cassidy, Gillian R. Lauder
DOI: 10.1111/pan.12994
11/2016

Preoperative warming and undesired surgical and anesthesia outcomes in pediatric spinal surgery-a retrospective cohort study
Pediatric Anesthesia
Matthias Görges, Nicholas C. West, Wesley Cheung, Guohai Zhou, Firoz Miyanji, Simon D. Whyte
DOI: 10.1111/pan.12939
09/2016

A Procedural Electroencephalogram Simulator for Evaluation of Anesthesia Monitors
Anesthesia & Analgesia
Christian Leth Petersen, Matthias Görges, Roslyn Massey, Guy Albert Dumont, J. Mark Ansermino
DOI: 10.1213/ane.0000000000001506
07/2016

Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: a retrospective study
Pediatric Anesthesia
Matthias Görges, Simon D. Whyte, Shubhayan Sanatani, Joy Dawes, Carolyne J. Montgomery, J. Mark Ansermino
DOI: 10.1111/pan.12780
10/2015

Development of mHealth Applications for Pre-Eclampsia Triage
IEEE J. Biomed. Health Inform.
Dustin T. Dunsmuir, Beth A. Payne, Garth Cloete, Christian Leth Petersen, Matthias Gorges, Joanne Lim, Peter von Dadelszen, Guy A. Dumont, J. Mark Ansermino
DOI: 10.1109/jbhi.2014.2301156
11/2014

Dexmedetomidine and hydromorphone: A novel pain management strategy for the oncology ward setting during anti-GD2 immunotherapy for high-risk neuroblastoma in children.
Matthias Görges, Nicholas West, Rebecca Deyell, Pamela Winton, Wesley Cheung, Gillian Lauder
DOI: 10.1002/pbc.25197
PubMed: 25263424
09/2014

No BP During NIBP
Matthias Görges, J. Mark Ansermino
09/2014

Identifying a rapid bolus dose of dexmedetomidine (ED50) with acceptable hemodynamic outcomes in children.
Joy Dawes, Dorothy Myers, Matthias Görges, Guohai Zhou, J Mark Ansermino, Carolyne J Montgomery
DOI: 10.1111/pan.12468
PubMed: 25040186
07/2014

A Scheme-based Closed-Loop Anesthesia System
Christian L Petersen, Matthias Görges, J Mark Ansermino, Guy A Dumont
DOI: 10.1145/2635648.2635651
2014

Evaluation of the effect of information integration in displays for ICU nurses on situation awareness and task completion time: A prospective randomized controlled study.
Sven H Koch, Charlene Weir, Dwayne Westenskow, Matthias Gondan, Jim Agutter, Maral Haar, David Liu, Matthias Görges, Nancy Staggers
DOI: 10.1016/j.ijmedinf.2012.10.002
PubMed: 23357614
08/2013

An Evaluation of an Expert System for Detecting Critical Events During Anesthesia in a Human Patient SimulatorA Prospective Randomized Controlled Study
Anesthesia & Analgesia
Matthias Görges, Pamela Winton, Valentyna Koval, Joanne Lim, Jonathan Stinson, Peter T. Choi, Stephan K. W. Schwarz, Guy A. Dumont, J. Mark Ansermino
DOI: 10.1213/ane.0b013e3182975b63
08/2013

Changes in cardiac index and blood pressure on positioning children prone for scoliosis surgery.
Zoe E Brown, Matthias Görges, Erin Cooke, Stephan Malherbe, Guy A Dumont, J Mark Ansermino
DOI: 10.1111/anae.12310
PubMed: 23710730
07/2013

A retrospective audit to examine the effectiveness of preoperative warming on hypothermia in spine deformity surgery patients.
Matthias Görges, J. Mark Ansermino, Simon D. Whyte
DOI: 10.1111/pan.12204
PubMed: 23738627
06/2013

Experience report: functional programming of mHealth applications
Christian L Petersen, Matthias Görges, Dustin Dunsmuir, Mark Ansermino, Guy A Dumont
DOI: 10.1145/2500365.2500615
2013

Mobile Patient Monitoring for the Pediatric Intensive Care Unit: Work Domain Analysis and Rapid Prototyping Results
Matthias Görges, Plinio P. Morita, Catherine M. Burns, J. Mark Ansermino
DOI: 10.1109/SMC.2013.642
2013

Evaluation of an integrated intensive care unit monitoring display by critical care fellow physicians.
Matthias Görges, Dwayne R Westenskow, Boaz A Markewitz
DOI: 10.1007/s10877-012-9370-0
PubMed: 22588528
12/2012

Intensive care unit nurses' information needs and recommendations for integrated displays to improve nurses' situation awareness.
Sven H Koch, Charlene Weir, Maral Haar, Nancy Staggers, Jim Agutter, Matthias Görges, Dwayne Westenskow
DOI: 10.1136/amiajnl-2011-000678
PubMed: 22437074
07/2012

University of Queensland Vital Signs DatasetDevelopment of an Accessible Repository of Anesthesia Patient Monitoring Data for Research
Anesthesia & Analgesia
David Liu, Matthias Görges, Simon A. Jenkins
DOI: 10.1213/ane.0b013e318241f7c0
03/2012

A Far-View Intensive Care Unit Monitoring Display Enables Faster Triage
Dimensions of Critical Care Nursing
Matthias Görges, Kai Kück, Sven H. Koch, Jim Agutter, Dwayne R. Westenskow
DOI: 10.1097/dcc.0b013e31821b7f08
07/2011

Medical device alarms
Biomedizinische Technik/Biomedical Engineering
Matthias Borowski, Matthias Görges, Roland Fried, Olaf Such, Christian Wrede, Michael Imhoff
DOI: 10.1515/bmt.2011.005
01/2011

A tool predicting future mean arterial blood pressure values improves the titration of vasoactive drugs.
Matthias Görges, Dwayne R Westenskow, Kai Kück, Joseph A Orr
DOI: 10.1007/s10877-010-9238-0
PubMed: 20559863
06/2010

Evaluation of an Ambient Color-Coded Display to Communicate Changes in the Patient’s Condition to ICU Nurses and Improve the Therapeutic Environment
Sven H Koch, Matthias Görges, Charlene Weir
DOI: 10.1177/154193121005401944
2010

Evaluations of physiological monitoring displays: a systematic review.
Matthias Görges, Nancy Staggers
DOI: 10.1007/s10877-007-9106-8
PubMed: 18064532
02/2008

Research

VitalPAD: an intelligent monitoring and communication device to optimize safety in the pediatric intensive care unit (PICU)
The goal is to develop a unified, portable and intelligent device that integrates information from multiple patient monitors, mechanical ventilators, infusion pumps and clinical information systems. It will allow PICU healthcare team members, on or off-site, to monitor critically ill patients continuously. The project involves two components: a) We will use feedback obtained in a participatory design process to guide the development of the VitalPAD, and b) We will use simulated ICU scenarios, to evaluate whether clinicians will prioritize the care of critically ill patients more rapidly and more accurately with the use of VitalPAD than without it.

Sepsis modeling and outcome prediction
Severe sepsis and septic shock are associated with a high burden of morbidity and mortality among critically ill children. Through improvements in supportive care, secular trends reveal a gradual decline in mortality. In collaboration with our critical care colleagues, our goal is to use a large North-American registry cohort to validate and compare the performance of existing risk score, identify new combinations of risk factors, and to develop novel outcome prediction tools.

Automated intravenous anesthesia delivery to improve outcomes
As a highly experienced, interdisciplinary team of engineers and clinician-scientists, we have developed a system that automatically adjusts drug dosing. It does so by comparing feedback on anesthesia depth, using processed electrical activity from the patient's brain to a clinician-selected target. By administering the right amount of anesthesia drugs to patients, it minimizes side effects of these drugs, and allows clinicians to focus on optimizing patient safety through complex, high-level decision making. We are currently evaluating the performance of this system during general anesthesia for both adults and children. Future work includes expanding this work towards other users, such as nurses, and settings, such as intensive care unit sedation.

Grants

2016-07, Project Grant, Canadian Institutes of Health Research

2016-04, Residents' Research Grant [PI: Terri Sun], Canadian Anesthesiologists' Society

2017-03, Evidence to Innovation Seed Grant, BC Children’s Hospital Research Institute (BCCHR)

2018-03, Evidence to Innovation Seed Grant, BC Children’s Hospital Research Institute (BCCHR)

2018-06, Designing for People (DFP) Project Origination Fund, University of British Columbia

Honours & Awards

2018-06, DFP Design Showcase Unicorn award. [KT Johnson presented the work], Designing for People – Human Computer Interaction @ UBC Initiative

2017-05, 2017 Abstract Scholarship award. [C Peters presented the work], American Thoracic Society

2018-05, 2nd place - Poster Presentations. [R Ridgeway presented the work], Anesthesiology Pharmacology & Therapeutics Research Day, University of British Columbia

2018-01, Best Clinical Application Award. [D Dunsmuir presented the work], Society for Technology in Anesthesia

2017-09, Research Day 2017 Award of Excellence - Outstanding Research Poster Presentation [KT Johnson presented the work], Evidence to Innovation Theme, BC Children's Hospital Research Institute

2018-01, Best of Show Award. [K Allen and I co-presented the work], Society for Technology in Anesthesia

Research Group Members

Nicholas West
Cynthia Liu
Luisa Flohr
Jasper Yoo, Project Assistant
Andrew Poznikoff, Clinical Research Coordinator
Rosa Hillgruber
Celine Hügel
Niema Ghanad Poor
Taneille Johnson