Indigenous Background Variant Library
Wyeth W. Wasserman
PhD, Executive Director, BC Children’s Hospital Research Institute, Associate Dean for Research, Faculty of Medicine, Senior Scientist, Centre for Molecular Medicine and Therapeutics; Professor, Department of Medical Genetics, University of British Columbia
Co-Project Leader and Team Lead Activity 3
Having worked in the biotechnology and pharmaceutical industry in both North America and Europe, Dr. Wasserman’s research focuses on projects with applied biomedical impacts. His computational biology laboratory develops computer algorithms for the analysis of human DNA sequences. Originally established at Sweden’s Karolinska Institute and since 2002 at the University of British Columbia, Dr. Wasserman’s lab provides international leadership in the identification and engineered design of DNA sequences that control when and where in the body each gene is active – the On and Off switches. With the arrival of low cost DNA sequencing for patients, his team works closely with clinicians at BC Children’s Hospital to discover the genetic causes impacting patients and families. He has published over 150 peer-reviewed papers, participated in over $25-million of funded research, and supervised more than 60 graduate and post-doctoral trainees.
Dora is a Research Manager in the Wasserman and Taubert labs, at the Centre for Molecular Medicine and Therapeutics (CMMT), University of British Columbia situated at the BC Children's Hospital Research Institute, in Vancouver. She has been working in UBC about 20 years, and is responsible for overall finances and works collaboratively on other administrative operations of the Silent Genomes project.
Postdoctoral fellow, Wasserman lab, University of British Columbia
Solenne is a postdoctoral fellow in the Wasserman lab, at the Centre for Molecular Medicine and Therapeutics (CMMT), University of British Columbia situated at the BC Children's Hospital Research Institute, in Vancouver. Trained in genetics, genomics and bioinformatics (University de Rennes, France), she works on the conceptualization and development of the Indigenous Background Variant Library (IBVL).
Bioinformatics Programmer, Wasserman lab, University of British Columbia
Brittany has completed her B.A.Sc. in Biomedical Engineering with a Minor in Computing Science and currently works on various programming projects within the Wasserman lab. As part of the Silent Genomes project, she will help in the development of a web interface to allow physicians access to collected variant and gene information.
is a B.Sc. in Biology and a Master student candidate in Bioinformatics at the CMMT. His previous work experience includes creating databases and analysis pipelines for genomic data, and web development. In the Silent Genomes Project, Alejandro’s participation involves the generation of the database that will store variant and gene information, as well as building a user-friendly web interface that allows physicians readily access and use such data.
PhD candidate, Wasserman lab, University of British Columbia Phillip is studying bioinformatics applied to rare disease genomics. Since 2015, Phillip has been interacting with the BCCHR IT department to establish clinical grade compute clusters for patient genomic data analysis. Within this timeframe he has implemented genomics workflows on several iterations of the BCCHR Genome Analysis Cluster, and currently serves as the manager of the multi-user system. As a member of the Silent Genomes team, his initial role in this project is to help establish a secure compute environment for the processing and storage of Silent Genomes whole genome sequencing data. This includes interacting with BCCHR IT to coordinate cluster purchasing and deployment of the compute server.
PhD, Associate Professor, Anthropology, Carl R. Woese Institute for Genomic Biology, University of Illinois
PhD, Assistant Professor, Department or Human Genetics, McGill University Canada Research Chair in Population and Statistical Genetics
MD, MSc, MSc, FRCPC, FCCMG Professor, Medical Genetics, University of British Columbia; Affiliate Professor, Division of Medical Sciences, University of Victoria